REMODELLING OUR STORES, WE'LL REMODEL ABOUT 300 STORES THIS YEAR.
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HONG KONG, June 26 (Reuters) - Takata's failure is remodelling the auto-safety industry.
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Matsuya Foods Holdings Co is remodelling some of its beef bowl restaurants to self-service.
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The team suspect that the remodelling of the gut microbiota was the cause for this drop.
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So last year it was a little bit of a drag because we were remodelling so many restaurants.
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Lian Li has just started shipping the DK-04X, so start thinking about remodelling your office right now.
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But his remakes are less like remodelling old structures than like raising entirely different buildings on their foundations.
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The firm used this approach when remodelling the Royal Court in London, a Victorian playhouse dating back to 193.
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There she finds the old version of the family bar, untouched: Oscar's remodelling only went halfway across the room.
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DJing is about the creation of the new from the existing, remodelling disparate sounds and corralling them into something approaching cohesion.
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She misses the practice of making clothes, which she discovered while in high school, first by deconstructing existing garments and remodelling them.
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Enrique's rainbows, displays, and castles lost the splendor of those first days, when almost all the toys participated in his radical remodelling.
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"Taken together, these observations are suggestive of a compensatory/remodelling process contributing to the cortical thickness variations in schizophrenia," the paper concludes.
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YOU'RE REMODELLING STORES, YOU'RE ADDING NEW STORES, EXPANDING YOUR FULFILLMENT CAPABILITIES, BUT YOU'RE ALSO, IN A WAY, PUTTING A STRAIN ON THE STORES.
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Marked by a stunning glass facade and three glazed steel structures, Gulita has seen hectic remodelling work in the months leading up to the wedding.
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In all, he'd had half a dozen procedures on his eyes, and, just a week before the conference, had completed a third remodelling of his nose.
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Houzz, the home remodelling site with a focus on giving you house envy, today announced that it is opening up its Commerce API for third-party developers.
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If Europe's single currency is to survive a global slowdown or another crisis it will require a remodelling that politicians seem unwilling or unable to press through.
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Sprint has plans to strategically improve its distribution through targeting increased store densification in underpenetrated areas, relocating poorly performing stores, remodelling/updating certain retail locations and migrating to more sophisticated prepaid dealers.
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WHAT WE LAID OUT A YEAR AGO, THE $7 BILLION INVESTMENT PLAN, WE ALREADY MADE THE COMMITMENTS TO ACCELERATE OUR CAPITAL EXPENDITURES, REMODELLING OUR STORES, BUILDING NEW CAPABILITIES, INVESTING IN OUR BRANDS.
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In July, police raided the headquarters of Korean Air Lines Co Ltd as part of an investigation into the suspected use of corporate money for remodelling work at the home of Chairman Cho Yang-ho.
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After the 2015 Memorial Day floods devastated her house in Houston's Meyerland neighborhood, she took her time remodelling the house that her parents had bought in 1969, the house that she had grown up in.
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Standalone Coach FCF is expected to be about $120 million in FY 13 and increase to $350 million to $400 million annually over the next two to three years as remodelling activity moderates and capex declines to about $200 million.
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These initiatives include the launch of all-day breakfast, menu strategies that focus on core equities such as the limited time offering of a Grand Mac and Mac Jr. sandwich, remodelling associated with the company's EOF initiative, and a renewed focus on value.
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ONE, WE WANT TO MAKE SURE WE PROVIDE A GREAT EXPERIENCE THAT'S REALLY INSPIRING WHEN YOU ARE IN OUR STORES, SO THAT'S WHY WE ARE REMODELLING, OPENING UP NEW STORES LIKE WE DID HERE IN HERALD SQUARE, OFFERING NEW BRANDS TO OUR GUESTS.
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BMW is now remodelling the southern section of the Dadong plant to increase the factory's flexibility, while another plant in Tiexi in the west of Shenyang, builds a long-wheelbase version of the X1 offroader, a 2 series, a long-wheelbase 3 series and a 1-series sedan.
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While you may mostly look at Houzz as a mobile app and website that features beautiful home remodelling photography in an effort to connect you to the professionals behind these projects, the service also features a thriving marketplace that aims to sell you the products needed to complete your next kitchen or bathroom remodel.
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KEY ASSUMPTIONS Fitch's key assumptions within our rating case for the issuer include: - moderate like-for-like sales growth driven by management's initiatives to support French like-for-like sales in a highly competitive environment, and cautious expansion pace; - EBITDA margin sustainable at 14.2% over FY18-FY20; - capex average 3% of sales per annum, reflecting continual investments in store remodelling, IT, as well as moderate expansion through owned stores; - no dividend payments; - average annual FCF at 3.8% of sales over FY18-FY19.
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KEY ASSUMPTIONS Fitch's key assumptions within our rating case for the issuer include: - Moderate like-for-like sales growth, driven by management's initiatives to support French like-for-like sales in a highly competitive environment, and cautious expansion pace; - EBITDA margin sustainable at or above 7503% over FY18-FY21; -Capex averaging 3% of sales per annum, reflecting continual investments in store remodelling, IT, as well as moderate expansion through own stores; -No dividend payments and no M&A activity; and -Average annual FCF at 4.3% of sales over FY18-FY21.
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Beuckers dated this remodelling to the time of Abbess Sophia.Beuckers, Marsusschrein, p. 112. In this remodelling, the collars of the ends of the cross became pointless and the goldsmith responsible for the remodelling concealed them with spiral-shaped filigree wire, known as ' (beehives). This ornamental motif came into vogue in the reign of Henry II (r.
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The total cost of the remodelling and amplification was €242 million.
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The architect for the remodelling and extension was the NER's William Bell.
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Both in vivo study and modelling are necessary tools to understand this complex process. Vascular remodelling is pertinent to wound healing and proper integration of tissue grafting and organ donations. Promoting an active remodelling process in some cases could help patients recover faster and retain functional use of donated tissues. However, outside of wound healing, chronic vascular remodelling in the adult is often symptomatic of cardiovascular disease.
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It owes its current look to a 19th-century remodelling in the historicist style.
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The remodelling in 1972 introduced film projection facilities, which have been used regularly since 1987.
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Herald Sun. Published 24 November 2011. Retrieved 24 November 2011. and remodelling his bowling action.
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It is a 15th-century church with major 17th-century remodelling in the Baroque style.
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Matrix-remodelling associated 5 is a protein in humans that is encoded by the MXRA5 gene.
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In 2018, a spokesman for Network Rail said remodelling the station could be complete by 2022.
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The hormone estrogen is also important for osteoblast regulation. In postmenopausal women estrogen levels are decreased which has negative effects on bone remodelling. Homocysteine further exacerbates this problem by reducing estrogen receptor α mRNA transcription. Thus reducing any beneficial effect that estrogen plays on bone remodelling.
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Moggerhanger House in Bedfordshire (1809) Country homes for the landed gentry included: new rooms and remodelling of Wimpole Hall and garden buildings, (1790–94) for his friend Philip Yorke whom he met on his Grand Tour; remodelling of Baronscourt, County Tyrone, Ireland (1791);Tyringham Hall (1792–1820); and the remodelling of Aynhoe Park (1798). In 1804, he remodelled Ramsey Abbey (none of his work there now survives);Stroud, 1984, p. 189 the remodelling of the south front of Port Eliot and new interiors (1804–06); the Gothic Library at Stowe House (1805–06); Moggerhanger House (1791–1809); for Marden Hill, Hertfordshire, Soane designed a new porch and entrance hall (1818);Stroud, 1984, p. 209 the remodelling of Wotton House after damage by fire (1820); a terrace of six houses above shops in Regent Street London (1820–21), demolished;Stroud, 1984, p.
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He also designed the parterres below the house.Bisgrove, P.181 Little of Barry's interior design survived later remodelling.
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Blood vessels form that penetrate the Haversian system. Remodelling of lamellar bone results in healing without callus formation.
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This remodelling was made possible by the realignment of Landesstraße (State Road) 160, which now bypasses the village.
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HAND domain-containing proteins include proteins involved in nucleosome remodelling, an energy-dependent process that alters histone-DNA interactions within nucleosomes, thereby rendering nucleosomal DNA accessible to regulatory factors. The ATPases involved in nucleosome remodelling belong to the SWI2/SNF2 subfamily of DEAD/H-helicases, which contain a conserved ATPase domain characterised by seven motifs. Proteins within this family differ with regard to domain organisation, their associated proteins and the remodelling complex in which they reside. The ATPase ISWI is a member of this family.
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J Card Fail 2009; 15:S34 These two proposed mechanisms illustrate therapeutic potential for the reduction of fibrotic remodelling in the hypertensive heart. Through combined effects of CNP and DNP, CD-NP treatment results in a reduction in stress on the heart (through natriuresis/diuresis) and inhibition of pro-fibrotic, remodelling pathways.
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A large maintenance was undertaken by Alexander_Ross_(architect) which included adding skews. In the final remodelling a gallery was placed at the opposite end to the pulpit. Under the gallery are two vestry rooms, steps up to the gallery and a passageway to the porch. The entrance porch was an addition during the remodelling.
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Hargreaves also investigates epigenetic chromatin remodelling with a goal of identifying therapeutic targets that harness the immune system to defend against tumors.
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The house was built in 1753 and incorporated some features from a previous building. It underwent significant remodelling in the 19th century.
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Although some remodelling of individual offices has occurred, the interior public spaces remain substantially intact and sustain the ambience of a 1930s building.
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Finally, in the field of heritage site restoration, the company rehabilitated the Roman Forum and the remodelling of La Seo Cathedral in Zaragoza.
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The Homestead became the CIty Museum, and a number of changes have been made, most notably the remodelling of the ell in 1966.
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Although the methods of action are not yet completely understood, it is hypothesized that medication-associated osteonecrosis of the jaw is related to a defect in jaw bone healing and remodelling. The inhibition of osteoclast differentiation and function, precipitated by drug therapy, leads to decreased bone resorption and remodelling. Evidence also suggests bisphosphonates induce apoptosis of osteoclasts.Lindsay R, Cosman F. Osteoporosis.
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Around the end of the 18th century, the church was constructed within the remodelling of the Largo Marquês de Pombal by Joaquim Guilherme d'Oliveira.
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At 36 months FU, the improvement on infarct size persisted, as well as the effect LV function. A progressive improvement of cardiac remodelling was noted.
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Furthermore, the use of latrunculin A was able to impair late phase LTP in this model, again suggesting that actin remodelling is necessary for LTP.
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The Rio Earth Summit in 1992 led to the remodelling of chemical assessment regimes under cooperative agreements with New Zealand, Canada and the United States.
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Taber, L.A. (June, 2001). Biomechanics of Cardiovascular Development. Annual Review of Biomedical Engineering 3: 1 – 25. Angiogenesis is also known to occur during vascular remodelling.
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The abnormalities seen in the great arteries of mice deficient of Tbx1 are a consequence of abnormal formation and remodelling of the aortic arches during early development. The role of Tbx1 for correct formation and remodelling of the aortic arches has been extensively studied in various mouse models suggesting the key role of Tbx1 for cardiovascular development and the phenotypes seen in DiGeorge syndrome.
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In 2009, the new Towner Gallery was opened, abutting the listed Congress Theatre built in 1963. In 2016–19 extensive remodelling work was undertaken to the prominent Arndale Centre, which takes up most of the town centre, and was originally built by Legal & General Assurance in the 1980s. This was then renamed The Beacon. The remodelling including the addition of a brand new cinema run by Cineworld.
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Cytotoxic cells expressing granzyme B have been identified close to hair follicles linking a possible role in hair loss. The ECM remodelling properties of granzyme B have also implicated its involvement in left ventricular remodelling, which increases the subsequent chances of myocardial infarction. The weakening of the fibrous cap of atheromatous plaques by apoptosis of smooth muscle cells has also been linked to granzyme B.
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It is known that mechanical forces can have a dramatic impact on the morphology and complexity of the vascular tree. However, these forces have comparably little impact on the diffusion of nutrients, and it therefore seems unlikely that acquisition of nutrients and oxygen plays a significant role in embryonic vascular remodelling. It is now widely accepted that vascular remodelling in the embryo is a process distinct from vasculogenesis; however these two processes are inextricably linked. Vasculogenesis occurs prior to vascular remodelling, but is a necessary step in the development of the blood vessel network and has implications on the identification of vessels as either arterial or venous.
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The main difficulty in the in vivo study of embryonic vascular remodelling has been to separate the effects of physical cues from the delivery of nutrients, oxygen, and other signalling factors which may have an effect on vascular remodelling. Previous work has involved control of blood viscosity in early cardiovascular flow, such as preventing the entry of red blood cells into blood plasma, thereby lowering viscosity and associated shear stresses. Starch can also be injected into the blood stream in order to increase viscosity and shear stress. Studies have shown that vascular remodelling in the embryo proceeds without the presence of erythrocytes, which are responsible for oxygen delivery.
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In this sense, embryonic vascular remodelling can be considered a model of the same pathways which are activated in tumour growth, and increased understanding of these pathways can lead to novel therapeutics which may inhibit tumour formation. Conversely, angiogenesis and vascular remodelling is an important aspect of wound healing and the long-term stability of tissue grafts. When blood flow is disrupted, angiogenesis provides sprouting vessels which migrate into deprived tissues and restore perfusion. Thus, the study of vascular remodelling may also provide important insight into the development of new techniques to improve wound healing and benefit the integration of tissues from transplants by lowering the incidence of rejection.
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The Biologische Station Initiative Oberhundem e.V. occupies itself with conservation. It supports schools, holds exhibitions and acts as adviser in the remodelling of the spa gardens.
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Mechanotherapy was defined in 1890 as “the employment of mechanical means for the cure of disease”. Mechanotherapy employs mechanotransdution in order to stimulate tissue repair and remodelling.
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The Staircase Hall is of 1810–11, while the Library was decorated in 1820. The Long Gallery and the Great Drawing Room are part of Prichard's remodelling.
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The equilibrium of these forces plays a major role in vascular remodelling, but although the angiogenic mechanisms required to trigger the sprouting of new vessels have been studied, little is known about the remodelling processes required to curb the growth of unnecessary branches. Examples of biomechanical forces acting on connective tissue. From Gray's Anatomy. As blood perfuses the system, it exerts shear and pressure forces on the vessel walls.
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The local church is dedicated to John the Baptist and belongs to the Parish of Šentvid pri Stični. It dates to the 15th century with some 17th-century remodelling.
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It interacts with Mi-2/NuRD complex (nucleosome remodelling and histone deacetylase) complex, giving an instance where methylation and acetylation are not discrete and mutually exclusive, but intertwined processes.
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London: HMSO.Stevenson, pp. 11–28 Today the site includes the two 6-inch gun positions and associated magazines, but the Napoleonic blockhouse was mostly demolished during the 1890s remodelling.
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20, St Andrewgate, York - the house that Atkinson built for himselfThomas Atkinson (1729–1798) was an English architect, best remembered for remodelling Bishopthorpe Palace in the Gothic Revival style.
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After remodelling, it served as Osaka City Museum. Transformed again, the former army headquarters building now functions as a dining and shopping space, under the moniker MIRAIZA Osaka-jo.
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Recently, a collection of Sir Henry's letters and drawings has come to light revealing a great deal about these buildings and gardens at Newton. One of the earliest is a builder's final account for the main construction work dated 5 November 1717. The resultant remodelling was very successful, as the Hall's handsome west front would show. During this remodelling it was decided to install new sash windows, something of a contemporary design statement.
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This is scheduled to commence in 2011 with remodelling of the track layout in the Faversham, Margate and Ramsgate areas. Later the route through the Medway towns will be remodelled.
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The porch has open sides with turned rails, and the original inner door. The remodelling included the typical Severn Valley lobby- entry central chimney, with its triple-moulded brick stacks.
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RNA polymerase II transcription of ncRNAs is required for chromatin remodelling in the Schizosaccharomyces pombe. Chromatin is progressively converted to an open configuration, as several species of ncRNAs are transcribed.
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The former third platform track was taken out of use during the remodelling so that trains can no longer overtake at the station. Later, the third track was completely dismantled.
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The original configuration of suites has been retained, despite some remodelling of individual offices. The interior public spaces sustain the 1920s ambience. Ballow Chambers continues as a specialist medical office building.
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The remodelling includes meandering and reprofiling the riverbed, banks and adjacent land to create a more natural setting, in order to create a wetland habitat that will encourage a diverse wildlife.
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These studies confirmed that pRNA has a role gene silencing by targeting chromatin remodelling complex to a rDNA gene promoters where both pRNA sequence and structure are crucial for its function.
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As of 2017, All Saints Day School serves preschool through 8th grade, with 175 students and 30 teachers. In the summer of 2017 the school commenced remodelling its 13,000+ volume library.
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40.24) and rivalling Giambologna as the foremost sculptors of the late 16th century in Italy.Thomas Martin, Alessandro Vittoria and the Portrait Bust in Renaissance Venice: Remodelling Antiquity (Oxford University Press) 1998.
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St Peter's on North Hill In origin a Medieval church, St Peter's is on North Hill and largely consists of later Georgian material due to a major remodelling in 1758, but the building retains mediaeval fabric and underwent a further remodelling in 1895–96. During the Medieval period the church yard contained a large stone cross from which gospels were read during the Palm Sunday procession.Ashdown-Hill, John (2009) Mediaeval Colchester's Lost Landmarks. Published by Breedon Books.
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In September 2013, the MMRDA invited agencies to prepare a Detailed Project Report (DPR) for three proposed bridges. The first flyover is planned from Bandra-Kurla Link Road to CST Junction in Kurla, and the second will be from Mumbai University junction in Kalina to CST Road. The third DPR concerns the remodelling of the existing CST Bridge. After remodelling, the and 30 m wide bridge would be 100 m long and will 45 m wide.
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He performed remodelling of the royal palace according to the design of Karl Gotthard Langhans (1732–1808). The remodelling took place in 1795 to 1796 in the classical style. As a result, the wings surrounding the northern courtyard, a new staircase and utility rooms were added. In March 1813, during the War of the Sixth Coalition with Napoleon, King Frederick William III of Prussia announced two famous manifestos: "To My People" and “To My Military Commanders”.
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The inventory of equipment includes automotive, bike, carpentry and woodworking, electrical and soldering, home maintenance, metalworking, plumbing, remodelling, and yard and garden. The types of equipment include: hand tools, and power tools.
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He resumed playing in December 2001 after remodelling his action and having it cleared by Sri Lanka Cricket.(6 December 2001). "Perera back for Sri Lanka" – BBC News. Retrieved 13 May 2014.
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Due to the turbulence, France Soir was not published for a month and a half. Brunois brought in bi-lingual British photographer Jason Fraser to lead the tabloid remodelling of the paper.
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Once contraction of the heart begins, vascular remodelling progresses via the interplay of forces resulting from biomechanical cues and fluid dynamics, which are translated by mechanotransduction to changes at cellular and genetic levels.
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She particularly liked Greece, where she lived for many years and worked as an art dealer and interior decorator, remodelling homes and travelling the world to select antiquities for museums and art dealers.
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Sharer & Traxler 2006, pp.475-6. Martin & Grube 2000, p.189. In 799 he rededicated the tomb of Ruler 1. Ruler 8 oversaw an extensive remodelling of the upper levels of the Acropolis.
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Though probably first built in the 12th century, the interior dates from the 13th-century remodelling. The tracery and delicate decoration is a sophisticated example of Gothic architecture, probably dating from the 1230s.
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His designs for public houses, shops, and hotels tended to be Neoclassical. He also designed 16 schemes for remodelling or building new warehouses, and created workhouses in Whiston, Ormskirk, Runcorn, and West Derby.
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Rather than the individual houses, Berriew is best remembered for its half timbered cottages which cluster around the churchyard and along the banks of the river Rhiew. There are further examples in the township of Refail. These can probably be attributed to the architect Thomas Penson. In the late 1830s, at the same time as Penson was working on remodelling Vaynor Park in Berriew for John Winder Lion-Winder, he was also remodelling and building houses in Berriew for the Vaynor estate.
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Therefore, vascular remodelling does not depend on the presence of oxygen and in fact occurs before perfused tissues require oxygen delivery. However, it is still unknown whether or not other nutrients or genetic factors may have promotional effects on vascular remodelling. Measurement of parabolic velocity profiles in live embryo vessels indicate that vessel walls are exposed to levels of laminar and shear stress which can have a bioactive effect. Shear stress on embryonic mouse and chicken vasculature ranges between 1 – 5 dyn/cm2.
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Lastly, due to recent experiments, it seems that Nox2 also plays an important role in angiotensin II-mediated inward remodelling in cerebral arterioles due to the emittance of superoxides from Nox2-containing NADPH oxidases.
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LAGs may have been truly absent, or were possibly erased by extensive remodelling of the bone into adulthood, both of which would support permanently rapid growth in Lisowicia, similar to mammals and some dinosaurs.
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This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y.
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Around 1740 the buildings underwent extensive alterations, giving them a Georgian remodelling that is mostly intact today. The Cary family invested in further reconstructions throughout the 19th century, including the construction of a small brewery.
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These have included the remodelling of the churches, a new cemetery, Casa do Povo, children's playground and primary school, and the construction of the Centro de Dia de Nossa Senhora da Saúde (seniors day centre).
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He was also a tutor of J.M.W Turner and he helped start Turner's illustrious career in art. Both father and son did a great deal of remodelling and rebuilding on the church of St Laurence.
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By the end of 2010, attendance to the park was up to 144,000 people annually. This figures are based on the actual park admittance and ticket sales. The park underwent an internal remodelling in 2011.
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The three- story bay window which rises to an octagonal turret at the west end of the house was built as part of the 1895 remodelling. The south-facing two-story facade, made of locally cut red sandstone, remains substantially unchanged from the original 1800–05 construction. The wooden porch running the length of the facade appears to be a reconstruction, as part of the 1895 remodeling, of a similar original porch. The entire west end of the house went through substantial changes in the 1895 remodelling.
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From the middle of 1926 the name "Opportunity Schools", rather than Backward Schools, was adopted for these centres. Additions and remodelling were carried out at the school in 1961, and in 1962 the school was renamed the Baroona Opportunity School. A new toilet block was erected in 1964. Further remodelling of the school commenced in the early 1970s, and in 1975 a new amenities block was erected in place of the 1964 block, and a covered play area and new administration block were constructed.
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The inventory of equipment includes automotive, bike, carpentry and woodworking, electrical and soldering, home maintenance, metalworking, plumbing, remodelling, sustainable living, and yard and garden. The types of equipment include: sensors, serving, hand tools, and power tools.
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In 1871 the Lancaster architects Paley and Austin carried out further alterations, including the removal of the gallery, adding a north vestry and organ chamber, replacing the seating, remodelling the pulpit, and adding a new font.
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The inventory of equipment includes automotive, bike, carpentry and woodworking, electrical and soldering, home maintenance, metalworking, plumbing, remodelling, sustainable living, and yard and garden. The types of equipment include: microcontrollers, signage & displays, hand tools, and power tools.
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Her husband William Deane Barnes-Brand died on 30 December 1945. Oliver Hill carried out the remodelling of Madgehole Farm, Shamley Green, for her around 1957. She died in London in 1974 at the age of 84.
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The inventory of equipment includes bike, carpentry and woodworking, electrical and soldering, home maintenance, ladders, measuring, metalworking, plumbing, remodelling, yard and garden. The types of equipment include: hand tools, power tools, propane & gas power tools, wheelbarrows & wagons.
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Outside of the city, he was responsible for the remodelling of Peckover House in Wisbech, the enlargement of Coltishall Primary School and in 1873, the building of the Dereham Congregational Church are among his most notable works.
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History Press. 2010. p. 62 by a fire which caused substantial damage to several other buildings on Broadway. An extensive remodelling occurred at Trinity in 1978, during which the building was subdivided horizontally by Wyn Thomas & Partners.
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The nave and the chancel of the church date from the 14th century. A major remodelling of the church took place in the early 16th century. It was restored in the 19th century by E. F. Bishopp.
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Since the remodelling, the church has hosted a wider range of community activities. The current minister is Rev. John Gleghorn and its associate minister is Rev. Oliver McMullen both of whom joined the church in autumn 2019.
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The low Reynolds number present in all early vessels means that flow can be considered creeping and laminar. A low Womersley number means that viscous effects dominate flow structure and that boundary layers can be considered to be non-existent. This allows the fluid dynamic computations to rest upon certain assumptions which simplify the mathematics. During the first stages of embryonic vascular remodelling, high-velocity flow is not present solely in large-diameter vessels, but this corrects itself due to the effects of vascular remodelling over the first two days of blood flow.
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Human HGF plasmid DNA therapy of cardiomyocytes is being examined as a potential treatment for coronary artery disease (a major cause of myocardial infarction (MI)), as well as treatment for the damage that occurs to the heart after MI. After MI, the myocardium suffers from reperfusion injury which leads to death of cardiomyocytes and detrimental remodelling of the heart, consequently reducing proper cardiac function. Transfection of cardiac myocytes with human HGF reduces ischemic reperfusion injury after MI. The benefits of HGF therapy include preventing improper remodelling of the heart and ameliorating heart dysfunction post-MI.
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In 1979 Pascal Lamy was appointed to the post of Secretary General of the “Mayoux Committee”. During 1979-1981 he worked as Deputy Secretary General, then Secretary General of the Interministerial Committee for the Remodelling of Industrial Structures (CIASI) in the Treasury Department. In 1981 Pascal Lamy was technical Adviser, then Deputy Director (June 1982), Office of the Ministers for Economic and Financial Affairs (Mr Jacques Delors). Lamy became Deputy Secretary General, then Secretary General of the Interministerial Committee for the Remodelling of Industrial Structures (CIASI) in the Treasury Department.
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16, p. 699, May 1701]. Scarsdale died childless in 1707 and his titles passed to his nephew, Nicholas; a member of the Tory administration who spent large sums of money remodelling the family home of Sutton Scarsdale Hall.
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In 1752 Curzon acquired Hagley Hall, near Rugeley in Staffordshire, remodelling the house and redesigning the grounds. In 1760 he built Penn House near Amersham in Buckinghamshire, replacing an earlier Tudor building with a red brick country mansion.
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1850 and 1855.Dictionary of Irish Architects 1720 - 1940, Irish Architectural Archive In 1864 the third Earl began further remodelling, with some fitting being installed from the family's Dublin home, Charlemont House. The architect this time was William Barre.
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Following the remodelling and centralisation of the University campus in 2007, a new £2.5 million Social Learning Zone for student study and Students' Union bar was built. The building also houses the university library, student services and coffee shop.
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The signalling of the station is controlled from Siemens all-electric power frame of 1935. The cabin was closed and demolished in August 2002 during remodelling of the station layout in view with the gauge conversion of the lines.
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This led to a complete remodelling of the gas network in Retkinia.Odgłosy 21/1986, p. 4. Following the construction of the housing district, the church, which by the late 1970s was too small for the growing congregation, was expanded.
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The house is a two- story classic box house designed by Omaha architects Fisher and Lawrie. It underwent a remodelling in 1923, directed by Omaha architect F. A. Henninger. The frame building faces south. It has a footprint of .
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Nicolson, pp. 128–9; Rowse, p. 95. William III commissioned Nicholas Hawksmoor and Sir Christopher Wren to conduct a large, final classical remodelling of the Upper Ward, but the king's early death caused the plan to be cancelled.Robinson, p.
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The chapel has always been galleried, but the original gallery which had wooden Doric columns was replaced in the remodelling of about 1900 with the present gallery on iron columns. The chapel is part of the United Reformed Church.
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From 1997 to 2007, the Casón building was closed for remodelling and enlargement.The Casón del Buen Retiro: History Museo del Prado. Retrieved 25 May 2013. Projects included the excavation of two new floors, resulting in almost double the preexisting space.
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Given its status as a Bien de Interés Cultural, it is unlikely to ever be finished due to the restrictions placed on the remodelling of such buildings. The architects also reorganized the interior around two courtyards and a grand staircase.
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Christ Church, Bundaberg, John H. Buckeridge (1857–1934) was an English-born Australian architect, who built about sixty churches in Queensland and is also remembered for remodelling the interior of the Macquarie era church of St James', King Street, Sydney.
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Binstead has two churches the Methodist Church, built in 1889,Binstead Methodist Church and the Church of the Holy Cross, constructed around 1150 (though went through remodelling in the 13th and 19th centuries). The monastery Quarr Abbey is also located nearby.
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Internal renovations of the buildings focused on the remodelling of the existing atrium cores with the extensive use of Cross-laminated timber. British artist Scott King (artist) designed the building's facade, referencing the socialist Project Cybersyn and pictorial depictions of Utopia.
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However, this model does not take into effect the diffusion of oxygen or signalling factors which may play a role in embryonic vascular remodelling. These models consistently reproduce most aspects of the vasculature seen in vivo in several different specialized cases.
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A partial remodelling took place in 1971, and in 1980 the Polish Ministry of Internal Affairs decided to rebuild it for use as a rest area for officers. This work was halted in 1981, when martial law was imposed in Poland.
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Cânâ Bilsel. Remodelling the Imperial Capital in the Early Republican Era: the Representation of History in Henri Prost’s Planning of Istanbul. In: Power and culture : identity, ideology, representation / edited by Jonathan Osmond and Ausma Cimdiņa. – Pisa : Plus-Pisa university press, 2007.
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A study showed a significant association of a specific polymorphism of the EDN2 gene with increased incidence of atrial fibrillation in patients with hypertrophic cardiomyopathy. Overall, the evidence suggests that ET-2 could modulate vascular tone, tissue morphology and remodelling.
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The Tea Room Drill Hall was demolished in the 1950s. Remodelling of the main entrances took place in 1988. Columns and whole entry complex was remodelled in 1990 following damage to the overhead sign and pillars by heavy and high trucks.
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On 22 September 1716, he married Lady Mary Finch, a daughter of Daniel Finch, 2nd Earl of Nottingham, and his second wife, Ann Hatton. He succeeded his father to Wentworth Woodhouse in 1723, remodelling the house to its present form.
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She also bought much land surrounding the hôtel and considerably enlarged the property. In 1744, she bought the estates and lordships of Villegénis and Igny. She remodelled the château de Villegénis in 1755. The cost of the remodelling was 430,000 livres.
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Yet, it was the nearby hermitage of Nossa Senhora do Rosário that functioned as the parochial church of Lagoa, suggesting that Santa Cruz was under construction or remodelling. On 3 January 1692, vicar Salvador de Sousa suggested constructing a clock for the church, and during the 1844 remodelling, the frontispiece and tower were extended to make way for such a project. The Fazenda Real (Royal Treasury) paid 112$000 in 1731 for paintings and gilding of interior woodwork. This saw the beginning of expenses on the church, and included a similar payment of 1785 for 42$000 reis, worth of improvements.
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Several studies have shown that pRNA is vital in the recruitment and localization of the chromatin remodelling complex which is needed for gene silencing. EMSA supports the idea that pRNA is involved in heterochromatin formation as it showed that pRNA from a number of different species interacted with TIP5, the large subunit of the chromatin remodelling complex NoRC. Mutagenesis of pRNA showed that RNA secondary structure is vital for TIP5 binding as mutations that altered secondary structure prevented TIP5 binding. TIP5 binds to pRNA by an induced fit mechanism as TIP5 showed a greater sensitivity to protease digestion in the presence of pRNA.
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The inventory of equipment includes automative, bike, carpentry and woodworking, electrical and soldering, home maintenance, metalworking, plumbing, remodelling, safety equipment, sustainable living, yard and garden. The types of equipment include: network equipment, books, camping, cars, googles, helmets, handtools, packages, power tools, wheelbarrows & wagons.
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Pregnancy begins the physiological changes through a pattern of hormonal secretion and signal transduction thus initiating the remodelling of soft tissues, cartilage and ligaments. Over time, the ligaments could be stretched either by injury or excess strain and in turn may cause PGP.
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Dictionary of Ohio Historic Places. Vol. 1. St. Clair Shores: Somerset, 1999, 122. Its style is comparable to that of several other Gothic Revival churches in Mechanicsburg that were built in the late nineteenth century, despite a remodelling project conducted in 1901.
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Arteriogenesis is the process of flow- related remodelling of existing vasculature to create collateral arteries. This can occur in response to ischemic vascular diseases or increase demand (e.g. exercise training). Arteriogenesis is triggered through nonspecific factors, such as shear stress and blood flow.
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Continuous minor changes were implemented until, in 1926 it underwent improvements with expansion, remodelling and refurbishment. The Lion Brand was adopted as the company logo in 1910. Subsidiaries were then formed in South Africa, Australia, New Zealand and elsewhere (thirteen countries in all).
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Granzyme B has shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodelling. Elevated levels of granzyme B are also implicated in a number of autoimmune diseases, several skin diseases, and type 1 diabetes.
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View of the nave after the 2016 restoration. The altar is remodelled, the cathedra was put back to pre-1960 sanctuary remodelling and a new altar rail to match the new style of the sanctuary is installed. Saint Laurent-Marie-Joseph Imbert.
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BMC Cancer 2009 9:220. Vascular remodelling in non-embryonic tissues is considered to be symptomatic of disease progression. Cardiovascular disease remains one of the most common causes of death globallyMendis, S. et al. (2011). Global Atlas on Cardiovascular Disease Prevention and Control.
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In 2001, the Chaves city council began archeological prospecting during the remodelling work in the historic centre of Chaves. Under the Polis program, in 2008, there was work to repair and improve the bridge, along with improving the riverbanks near the bridge.
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The Valley Library In 1999, OSU finished a $40 million remodelling of the campus library. Known as the Valley Library, the totally remodelled building was selected by The Library Journal as their 1999 Library of the Year, the first academic library so named.
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Though his parentage and early career are unknown, he was established in independent practice in London by 1851. His works include Milner Field in Bingley (demolished), Bedstone Court and Stokesay Court in Shropshire and the remodelling of St Marylebone Parish Church in London.
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Marshall's Works steam engines were sold all over the world until it closed in the 1980s. The site has now been split among many different companies, Tesco on Beaumont Street and Dransfield's remodelling about nine acres. The remainder is occupied by local companies.
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During the remodelling, spiral arteries undergo structural changes to allow adequate nutritional substances to supply the growing foetus. In the mouse uNK cells were also found to produce growth-promoting factors which are important in early development before the placenta is fully formed.
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The Buquoys, whose main residence was in Nové Hrady, repaired and altered their family seat (1840–57), remodelling the building in the style of Romantic Neo-Gothic, and keeping it until 1945 when it was nationalised after the end of World War II.
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Fabyan Villa was the home of George and Nelle Fabyan from c. 1908 to 1939. The house is notable because of its remodelling in 1907 by Frank Lloyd Wright. It was the centerpiece of the Fabyans country estate, which they named Riverbank.
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Abbotswood Estate Abbotswood is a country house and estate near Lower Swell in Gloucestershire, England. It is a grade II listed building and estate, of medieval origins and with remodelling and garden work to the designs of Sir Edwin Lutyens from 1901 onwards.
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He undertook extensive remodelling of Compton Verney House to give it a more classical appearance. On his death on 26 December 1728 he was buried at Compton Verney and the title passed to his second son Richard, his eldest son having died.
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At this time Milthorpe had an area of .Branch Manager, 1986, p.5. Milthorpe is thought to have been built in 1872 by Richard Sim as a fourteen-room stone house. The building was given a Federation style appearance after remodelling around 1900.
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Ward, Julian. "The Remodelling of a National Cinema: Chinese Films of the Seventeen Years (1949–66)", in The Chinese Cinema Book, edited by Song Hwee Lim and Julian Ward (2011). BFI: Palgrave Macmillan, p. 90. The first widescreen Chinese film was produced in 1960.
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Ward, Julian. "The Remodelling of a National Cinema: Chinese Films of the Seventeen Years (1949–66)", in The Chinese Cinema Book, edited by Song Hwee Lim and Julian Ward (2011). BFI: Palgrave Macmillan, pp. 92–93.The Unfinished Comedy was only screened after Mao's death.
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This house has a datestone which may read 1694. It is built of coursed squared ironwork, with a tile roof and brick and stone stacks. The bay window on the left-hand side has a datestone reading 1925, when extensions and internal remodelling took place.
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In 1915, a permanent building replaced temporary accommodation in the Methodist Church. Citizen donations provided a $15,000 community hall. In 1920, the premier opened the two-storey hospital, which provided 15 beds on remodelling. Smithers became the first incorporated village for BC in 1921.
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Isolated examples included Logan House, designed by David Style in the 1950s. In the 1960s there was Basil Hughes's design at Snaigow for the earl of Cadogan and the remodelling of Gask House by Claude Phillimore. This period also saw considerable restoration of existing houses.
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The Estates Gazette, vol. 216, p. 261 In 1999, the property was acquired by Ryan Hotels for £16.9 million.Irish Times, 17 July 1999 Following further remodelling, it was operated as the Hyde Park Gresham Hotel until 2007 when it became the Park Inn Hotel.
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The SpåraKoff has an area of . It has seats for 24 customers, a counter and a lavatory. The lavatory is so small it had to be ordered from a company that builds cabins for cruise ships. The remodelling was done by Helsinki City Transport.
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In 2008 Tong High School went through a major remodelling. A new building was built and after vacating, the old building was demolished. In December 2016, the school converted to academy status, joining Tauheedul Education Trust (now Star Academies), and was renamed Tong Leadership Academy.
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The traction change meant that the number of employees in the depot dropped from 269 to 170.For statistics see Böttcher, Durchgangsbahnhof, p. 337. The total cost in 1972 of the remodelling of the station was DM 39.7 million.For statistics see Böttcher, Durchgangsbahnhof, p. 329.
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On his death it passed to his brother, Major John Grant of Dawlish, Devon. In 1830 a north wing was added. Subsequently there has been restoration work in 1890, remodelling other floors under the supervision of Alexander Marshall Mackenzie, and in the early 1980s.
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On the other side, the ballroom was connected to the Buffet Hall through three doors. Photos made after the war show the room with its vaulted ceiling collapsed. The ballroom was not restored but totally destroyed in the course of the post-war remodelling.
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Up-regulation of activin A works in conjunction with Fibrillin-1 and TGF-ß signalling molecules to produce a fibroproliferative response. CYR61 induction also functions to support cell adhesion and regulate matrix remodelling and is fundamental in the formation of large vessels and their integrity.
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Morris designed Combe Bank, Kent, in the second quarter of the century. John Harris has demonstrated that Morris made a design for the Porter's Lodge at Wilton House, ca. 1733.Harris 1984:231f. Remodelling of Lydiard Park, Wiltshire, in the 1740s is attributed to Morris.
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Some years the theatre was closed during which period it fell into a dirty and dilapidated state until March 1869 when it was bought by a Mr J. Fremantle who renovated and altered the theatre under the direction of the architect George Somers Leigh Clarke. In his remodelling Clarke added a Royal Box in the expectation that Queen Victoria and other members of the Royal Family would visit the theatre. The theatre was put up for auction in October 1869. Under the lesseeship of John Restall the theatre underwent further remodelling in 1900 by which time it was named the Theatre Royal and Opera House.
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Around 1600, a Jacobean mansion had been dovetailed around the pele, but today's hall is re-design of the house, using the original Elizabethan style. Cliveden House as seen from its lawn Barry's last major remodelling work was Cliveden House,Crathorne, PP.94–96 which had been the seat of the Earl of Orkney from 1696 till 1824. Barry's remodelling was again on behalf of the 2nd Duke of Sutherland. After the previous building was burnt down (1850–51), Barry built a new central block in the Italianate Style, rising to three floors, the lowest of which have arch headed windows, and the upper two floors have giant Ionic pilasters.
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Following the completion of her Doctoral work, Hargreaves joined the lab of Dr. Gerald Crabtree where she and others uncovered that the genes encoding subunits of the BAF Chromatin remodelling subunits are mutated in ~20% of all human cancers and uncovered mechanisms of BAF complex tumor suppression. Hargreaves was appointed professorship at the Salk Institute for Biological Studies in 2015 where she continues her focus on the chromatin remodelling complex BAF. Her lab has recently discovered a specific subunit of BAF that is responsible for maintaining cellular pluripotency, an unbiased differentiation state. Hargreaves' work holds potential in the realm of regenerative medicine for use in treating tissue damage and disease.
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These were elaborated the following year with upgrades to dressing rooms, the stage, washrooms and remodelling of the electrical systems, which included the installation of an electrical generator. Two years later (23 November) a proposal was issued by the DRPorto, to reclassify the Theatre as a Portuguese National Monument. Following a period of remodelling, the theatre began to function regularly, under the designation the Teatro Nacional de São João (São João National Theatre). In addition to general cleaning, the work included the consolidation and restoration of the exterior facades, recuperation of the decorative sculptures, treatment of surfaces in pigmented mortar and the installation of new woods and iron.
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Piazza Santa Maria Novella Giorgio Vasari was the architect, commissioned in 1567 by Grand Duke Cosimo I, for the first remodelling of the church, which included removing its original rood screen and loft, and adding six chapels between the columns. An armillary sphere (on the left) and a gnomon (on the right) were added to the end blind arches of the lower façade by Ignazio Danti, astronomer of Cosimo I, in 1572. The second remodelling was designed by Enrico Romoli, and was carried out between 1858 and 1860. The square in front the church was used by Cosimo I for the yearly chariot race (Palio dei Cocchi).
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They rebuilt much of the castle in the late 15th century, including remodelling the pele tower, the great hall and the gateway, complete with a polygonal barbican.Pettifer, p.47. The pele tower formed a substantial fortification, about by across, with three floors and thick walls.Taylor, p.345.
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The church was remodelled twice during the 19th century. The first took place in 1811–12. This was carried out either by Robert Smirke, or by George Gibson advised by Smirke. Remaining from this remodelling are the south porch and the south doorway of the chancel.
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Electronic interlocking and massive yard remodelling has been commissioned at Dadri station. Dadri is a complex yard in North Central Railway spread over six kilometres on busiest route of Delhi- Howrah section and also having connectivity with National Thermal Power Corporation Power Plant and Container Depot.
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The café reopened in 2009, following extensive remodelling begun in September 2008, under the auspices of ASAE Autoridade para a Segurança Alimentar e Económica (Food and Economic Security Authority); the renovation included work in kitchen and necessary replacement of the old wood beams with stainless steel frames.
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Lochnaw Castle was home to the Agnew family. The ruins of the Old Castle stand on an island in Lochnaw Loch, and date to the 13th century. The present castle incorporates a 16th-century tower house, but is largely the result of remodelling in the 18th century.
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During the Inquirições (inquiries/inventory) of King Afonso III of Portugal the church was referenced in its construction, noting the involvement of the stonemason Garcia Petrarius, who was likely a Moor.Carlos Almeida (1978), p.227-228 An inscription relating to later remodelling was unveiled in 1664.
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Among his legacies is the formal flower garden at Drummond Castle, for which he worked on the scheme with the architect and landscape designer Sir Charles Barry.Sir Charles Barry showed his watercolours of a scheme for remodelling Drummond Castle itself at the Royal Academy in 1828.
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Parish records for the Church of All Saints, Clifton are held at Bristol Archives (Ref. P.St ASC) (online catalogue) including baptism and marriage registers and plans of the remodelling from 1963. The archive also includes records of the incumbent, churchwardens, parochial church council, charities and choir school.
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The developer initially implemented the database as a triplestore, being a Semantic Web pioneer in Russia. Remodelling into a multi-model database was supported by the Skolkovo Innovation Center in 2017. The database is used in information systems that support the health-care reform in modern Russia.
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Sutton United play their home games at Gander Green Lane, officially the Knights Community Stadium for sponsorship reasons. Sutton United received the seats for the grandstand at Gander Green Lane from the remodelling of Stamford Bridge and were given to them by the Chelsea F.C. Pitch Owners.
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Mark Richard Rosenzweig (September 12, 1922 - July 20, 2009) was an American research psychologist whose research on neuroplasticity in animals indicated that the adult brain remains capable of anatomical remodelling and reorganization based on life experiences, overturning the conventional wisdom that the brain reached full maturity in childhood.
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The northern approach (NSW end) has been removed and replaced with a staircase that is considered to be unsympathetic and intrusive. Future remodelling of stairs or replacement would be recommended. The integrity has been spoilt by removal of northern approach spans but the remaining components are largely intact.
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Also in 1896, Brutton designed the St James's Tavern in Denham Street, in central London. In 1897, Brutton was responsible for the remodelling and extension of the Alhambra Theatre in Leicester Square, now the site of the Odeon Leicester Square. Brutton also designed the Princess Victoria in Shepherd’s Bush.
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In order to start a long-needed renovation of the church and the remodelling of its immediate neighbourhood, the Stiftung Heilige Elisabeth foundation was established in 2004 and supports the City of Marburg and the Protestant Church of Hesse-Kassel and Waldeck in the financing of the repair measures.
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The Malani Express is an express train belonging to Northern Railway zone that runs between Old Delhi and Barmer in India. It is currently being operated with 14659/14660 train numbers on daily basis.Mega Traffic Block For RRI Commissioning and Remodelling of Jodhpur Yard from 16.05.2016 to 09.06.
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Upon resolution of the type 2 junction, a new type 3 junctions forms perpendicular to the original type 1 configuration. During this process the two dorsal- ventral cells have become neighbors.Bertet, C., Sulak, L. & Lecuit, T. (2004). Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation.
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It has been described as one of the oldest stone castles in Scotland.Ewart; Triscott: pp. 555-556. The original castle was a simple enclosure, and was abandoned by the MacSweens in the 13th century. The Castle underwent extensive remodelling while in the possession of the Stewart earls of Menteith.
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The Thameslink Programme (formerly Thameslink 2000) is a £5 billion major project to expand the Thameslink network from 51 to 172 stations spreading northwards to Bedford, Peterborough, Cambridge and King's Lynn. The project includes the lengthening of platforms, station remodelling, new railway infrastructure (e.g. viaducts) and additional rolling stock.
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Sulfatases play important roles in the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodelling sulfated glycosaminoglycans in the extracellular space. Together with sulfotransferases, sulfatases form the major catalytic machinery for the synthesis and breakage of sulfate esters.
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Eighteen rooms were available for rental in the main building at 41st street in 1911. When demand exceeded availability, those seeking accommodation were sent to the Murray Hill Hotel. A restaurant served the needs of residents and visitors at the Club. Later remodelling increased the number of available rooms.
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The site of the station in the remodelling plan was designated as the site of the Führermuseum, with the station to be moved four kilometers to the south at the opposite end of a new main boulevard.Plaut (1946) However, these remodelling plans never came to fruition, and with the rebuilt station building damaged by Allied bombing during World War II, the station was rebuilt for a second time from 1949-1955 in the sober style of that time. By the end of the twentieth century, it was no longer appropriate to the increasing requirements of contemporary public transport. In 2002-2004, the rebuilt station building was completely replaced with a new building designed by Wilhelm Holzbauer.
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Nasir ad-Din Shah Qajar undertook the latest remodelling of the shrine in 1868, with the golden dome added in 1905. Covered in 72,000 gold pieces and surrounded by walls of light blue tiles, the dome was a dominant feature of the Samarra skyline. It was approximately in diameter by high.
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Ultimately, repeated acute episodes lead to wider scale damage of pulmonary structures (parenchyma) and function via irreversible lung remodelling. Left untreated, this manifests as progressive bronchiectasis and pulmonary fibrosis that is often seen in the upper lobes, and can give rise to a similar radiological appearance to that produced by tuberculosis.
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There are many other factors to consider. In healthy bone tissue there is a homeostasis between bone resorption and ossification. Diseased or damaged bone is resorbed through the osteoclasts mediated process while osteoblasts form new bone to replace it, thus maintaining healthy bone density. This process is commonly called remodelling.
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Hopetoun House, near Edinburgh, was completed in 1702, and represents Bruce's grandest country house design. The master mason was again Thomas Bauchop, and the inspiration was again Anglo-Dutch, with French rustication. The bulk of Bruce's work is now obscured by 18th-century remodelling, carried out by William Adam.Gifford (1989), p.
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William Courthope (Ed.), Debrett's Complete Peerage of the United Kingdom of Great Britain and Ireland (J. G. & F. Rivington, 1838), p.629-30 (Retrieved 5 October 2016). Powerscourt was responsible for commissioning the German architect, Richard Cassels, to carry out extensive remodelling work on Powerscourt House between 1731 and 1741.
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His achievement included remodelling Kirkleatham Hall, as well as providing for the further development of the hospital, school, and a library. He also built the adjoining village of Yearby. In 1894 Kirkleatham became an urban district, but was annexed by Redcar in 1899, after just five years as an independent authority.
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The mill maintained its own fire brigade with steam fire engine. By the end of the nineteenth century, Nash Mill, which was small and had a reputation for independence, experienced a drop in profitability. Continuous minor changes were implemented until, in 1926 it underwent improvements with expansion, remodelling and refurbishment.
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In the remodelling of the sanctuary a new wood panelled reredos was fitted and the communion rails extended forward at the sides. The pulpit was retained in its original position, but the babtismal font was reset. The choir was enlarged to accommodate 42. The architect was N. S. W. McPherson.
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At the end of the 20th century, remodelling continued with conservation, cleaning and restoration, including the main chapel in 1999 and the cloister in 1998–2002. On 13 December 2007, the Treaty of Lisbon was signed at the monastery, laying down the basis for the reform of the European Union.
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244 (3), 308 -14 The underlying mechanism is that BBP blocks the calcium signaling that is coupled with P2X receptors. Calcium signaling, mediated via P2X, eventually has an influence in cell proliferation and bone remodeling. During developmental phases of bone remodelling, high environmental exposure of BBP might therefore pose a problem.
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Siegen Pedestrian zone Siegen Town hall Apollo-Theater. Oberen Schloss Part of Unteres Schloss with "Fat Tower". 2006 World Cup match. In the Apollo-Theater (a downtown former 1930s cinema that underwent remodelling and opened in mid-2007), Siegen has one of the current decade's most important newly built theatres.
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John Mossman was an Edinburgh-based goldsmith who is most famous for remodelling the Scottish crown in 1540. He made a reliquary for a bone of St Adrian of May for James V from Scottish gold.James Balfour Paul, Accounts of the Treasurer of Scotland, vol. 7 (Edinburgh, 1907), p. 396.
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The spire was donated by William Pearce JP, a 19th-century Mayor of Poole, who resided at nearby Springfield House.Springfield, Parkstone, Poole, Dorset at www.flickr.com. Accessed on 11 September 2012. There was further remodelling in 1915 which saw the nave rebuilt with aisles and transepts by Herbert Kendell of Poole.
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All the other windows in the building are square-headed. The porches and first-floor balconies were removed in Hastings' remodelling. The first floor has four windows; over each of these is a pediment containing decorative plasterwork. The second floor has four windows, while the third floor has six windows.
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Victoria & Albert Museum, London. Her Majesty's Stationery Office (HMSO), p. 1. Much of his work consisted of remodelling existing houses, as well as contributions to Edinburgh's townscape and designing romantic pseudo-mediaeval country houses in Scotland. He served as the member of Parliament for Kinross-shire from 1768 to 1774.
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Ross Priory has been described as a Scottish Gothic style country house. It was designed in 1812 by Dunblane-born architect James Gillespie Graham (1776-1855) as an extensive remodelling of the site's existing farmhouse. Ross Priory comprises approximately of land and includes a formal garden, parkland, a burial ground and golf course.
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New York: McGraw- Hill. Additionally, chronic increase in production of AII is associated with structural changes to the myocardiumYamagishi H., Kim S., Nishikimi T., Takeuchi K., Takeda T. (1993). Contribution of cardiac renin-angiotensin system to ventricular remodelling in myocardial-infarcted rats. Journal of Molecular and Cellular Cardiology, 25(11):1369-80.
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The second remodelling took place over a period extending from 1848 to 1887. It was commissioned by the incumbent Revd George F. Weston, and carried out by J. S. Crowther. New furnishings were introduced in 1850, and the whitewash was removed. In 1854 the chancel arch was installed, and a vestry was added.
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As the 19th century progressed, the destruction and remodelling of the town walls continued. The upper stories of Polymond Tower were demolished in the 1820s, to be rebuilt by 1846 as a shorter, two-storey tower.MSH36, Southampton HER, accessed 14 October 2011. The remains of the South Gate were turned into a hotel.
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The Museum is part of the Barcelona Provincial Council Local Museum Network. Currently, the Ca n’Ortadó central building is closed to the public, immersed in an intense remodelling process in relation to the 2009 opening of the Cerdanyola Art Museum and that of the Ca n'Oliver Iberian Settlement and Museum, in 2010.
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View from the southwest The Wabash County Courthouse is a historic governmental building in downtown Mount Carmel, Illinois, United States. Built in the late nineteenth century as the fifth courthouse in Wabash County, it has experienced a series of extensive remodelling projects that have left it with virtually nothing of the original building.
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853, . The individual wings may directly adjoin the main building or may be built separately and joined to it by a connecting structure such as a colonnade or pergola. New buildings may incorporate wings from the outset or these may be added at a later date as part of an expansion or remodelling.
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In the 1890s the house underwent considerable remodelling. It was rendered in stucco, resashed, the front door replaced, the chair boards and other original joinery details removed inside. C.1900 the roof, originally shingled, was replaced by corrugated iron. The interior walls were wallpapered (and remained so until the 1970s)(Kemp,2001).
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The first event of biomechanical-driven hierarchal remodelling occurs just after the onset of heart beat, when the vitelline artery forms by the fusion of several smaller capillaries. Subsequently, side branches may disconnect from the main artery and reattach to the venous network, effectively changing their identity.le Noble, F. et al. (October, 2003).
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Representation of laminar flow between two walls. The pressure gradient at the fluid boundary layer (green) is transmitted to the walls by shear stress. Fluid dynamics also plays an important role in vascular remodelling. The shear stress applied to vessel walls is proportional to the viscosity and flow patterns of the fluid.
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World Health Organization: Geneva. and is often associated with the blockage or stenosis of blood vessels, which can have dramatic biomechanical effects. In acute and chronic remodelling, the increase in shear stress due to the decreased diameter of a blocked vessel can cause vasodilation, thereby restoring typical shear stress levels.Castier, Y. et al.
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According to Spang et al. Lokiarchaeota forms a monophyletic group with eukaryotes in phylogenomic analyses. The associated genomes also encode an expanded repertoire of eukaryotic signature proteins that are suggestive of sophisticated membrane remodelling capabilities. This work suggests a two-domain system as opposed to the near universally adopted three-domain system.
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This ultimately leads to airway remodelling and difficulty of breathing. Eosinophils can also cause tissue damage in the lungs of asthmatic patients. High concentrations of eosinophil major basic protein and eosinophil-derived neurotoxin that approach cytotoxic levels are observed at degranulation sites in the lungs as well as in the asthmatic sputum.
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De Brome's chapel has a two-bay arcade with continuous hollow chamfered arches with Perpendicular windows. The tall arch in this aisle, connecting with the tower is a 15th- century remodelling of a late 13th century window. Adam de Brome's tomb, the 14th century slab rests on a modern chest. Church's canopied pulpit.
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Victoria Gate is now directly across the road2016 update: from late 2016 Victoria Gate will be trading next to the market, and the Council plans to capitalise on this change in focus include remodelling to provide a new fresh and street food market area including an event space open from June 2016.
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The GRg1 affected three metabolic pathways: the metabolism of lecithin, amino acids and sphingolipids, while GRb1 treatment affected lecithin and amino acid metabolism. It was reported in 2017 that GRb1 improved cardiac function and remodelling in heart failure in mice. The treatment of H-ginsenoside Rb1 potentially attenuated cardiac hypertrophy and myocardial fibrosis.
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Crystals do not always cause acute inflammation but instead lead to chronic tissue remodelling. This process is possible because crystals get shielded from pro- inflammatory processes by compartmentalization (e.g. granuloma formation, fibrosis, and wound-healing) or molecular coating, or because inflammatory responses are suppressed with direct anti-inflammatory signalling (e.g. CLEC12A and NETosis).
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During this period, she also designed the interior of Houston's Central Public Library, a design lost through a remodelling project in 2008. From 1980, she worked independently. In 1986, she was inducted in the Interior Design Hall of Fame, the first Houstonian to be admitted. She died from leukaemia on January 12, 1992.
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It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling. CXCL5 has been also described to regulate neutrophil homeostasis.
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She found that this development of cell identity begins with heterogeneity in epigenetic regulation at the 4-cell stage that directs a molecular cascade establishing cell polarity, position and fate. Her recent development of systems permitting both mouse and human embryogenesis during implantation and early post-implantation stages in vitro allowed her to reveal that mouse and human embryo remodelling at implantation is done autonomously by the embryo. She uncovered the mechanism underlying embryo remodelling between the blastocyst and gastrula stages that has led to a change in the textbook model. Her demonstration of the self-organisation of human embryos developing in vitro until day 13/14, gastrulation, has provided an unprecedented opportunity to study human development at previously inaccessible and critical stages.
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The most famous historical instance of quo warranto was the action taken against the Corporation of London by Charles II in 1683.. The King's Bench adjudged the charter and franchises of the City of London to be forfeited to the Crown, though this judgment was reversed by the London, Quo Warranto Judgment Reversed Act 1689 shortly after the Glorious Revolution. But the remodelling of the City of London was only part of a wider remodelling of some forty chartered parliamentary boroughs by the CrownJ. H. Plumb, The Growth of Political Stability in England (London 1986) pp. 55-6. – a policy taken up again in 1688 by James II, when some thirty-five new charters were issued after quo warranto produced the surrender of the old ones.
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Hendon then became interested in exploring the structure-function relationship of the cervix and how characterizing this relationship could provide insight into causes of preterm birth and possible prevention strategies. Hendon first found that collagen fiber dispersion and directionality had an impact on cervical remodelling and thus propensity for preterm birth. Since this remodelling results in shortening of the cervix, which is thought to result in preterm birth, Hendon sought to further understand the structural properties that underlie shortening and elucidate approaches to prevent preterm birth. By assessing the collagen fiber orientation through her material modelling framework, Hendon was able to determine the basis for cervical deformation using OCT and biomechanically explore the causes of preterm birth at the level of tissue microstructure.
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The Chapel of Santo António was built in order to support the local garrison: its interior, although simple, was covered in artistic azulejo tile. After its remodelling, the pousada included 28 rooms and two suites, restaurant with esplanade, bar, conference and reading room (in addition to pool) was created from the main garrison's barracks.
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From 1998 until 2001, Ruf was the director of Kunsthaus Glarus. In 1999, she joined the board of the Schweizerische Graphische Gesellschaft (SGG). Ruf replaced Bernhard Bürgi in 2001 as director at Kunsthalle Zurich. In 2012, she completed the acquisition, remodelling and extension of the Kunsthalle Zürich building at the Löwenbräu building in Zürich.
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Webb was also responsible for the remodelling of Crewe station which involved the building of four tracks in underpasses on the west side of the station to carry freight trains. He made numerous inventions and received over 80 patents. He was Vice-President of the Institution of Civil Engineers and the Institution of Mechanical Engineers.
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Potter LR, Yoder AR, Flora AR, Antos LK, Dickey DM. Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications. Handb Exp Pharmacol 2009; 191:341-366 Fibrotic heart tissue is associated with an increase risk of ventricular dysfunction which can ultimately lead to heart failure.Kenchaiach S, Pfeffer MA. Cardiac remodelling in systemic hypertension.
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An up- regulation of egfl7 is observed in endothelial cells during vascular remodelling tissues, such as in reproductive organs during pregnancy, in regenerating endothelium following arterial injury, in atherosclerotic plaques, and in growing tumours. Expression of egfl7 has also been reported in primordial germ cells and in adult ovaries and testes and in neurons.
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The estate was subsequently acquired by the banker and archaeologist John Lubbock, 1st Baron Avebury (1834-1913), who enlarged Kingsgate Castle as his residence.John Guy. Kent Castles Meresborough Books 1980 p141 Holland House's surviving façade dates from a remodelling circa 1850-40. The original central portico was removed to the Sea Bathing Hospital at Margate.
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Under the remodelling, the old grandstand stand was refurbished to house the VIS and included a state of the art gym, swimming pool and clubrooms. A blue running track in reference to the home colour of the club was also constructed for the Athletics division. Today, Lakeside Stadium is one of Australia's premiere stadiums.
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Other commercial spaces were eventually opened on the ground floor. By the 1990s, a library existed in the location. The construction company, Lucios, demolished the interiors in 2004, transforming the spaces into 10 residential apartments (between T0 and T2 configurations). The project also included the remodelling of the roof and construction of an elevator.
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Their brother was John Heneage (1484-1557), a member of Parliament, and their nephew was Sir George Heneage (c. 1520-1595), also a member of Parliament. It seems likely that the church was demolished at an early stage of remodelling the site, churches being generally seen as a profitable source of lead and building materials.
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This remodelling occurred in 1942 at a cost of and involved limiting access to Richmond Street, removing internal partitions on the ground floor level and removing six fireplaces. Also new stairs were constructed in three of the four corners of the building and a stables was demolished to make way for an air raid shelter.
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In January 2018, it was announced that half the station would close for 3 months from January to March 2020 for remodelling work to the station and its approach, expected to cost £237 million. This includes rationalisation of the tracks, reopening the third tunnel to the approach of the station and closure of platform 10.
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On site facilities include a swimming pool, a library, and a cashless vending system operated by the user's thumbprint. The school retains all of its original 1950s structures, but renovation work has been put into the Science rooms, giving them a complete refit, the Art and Design & Technology rooms (in some cases completely remodelling them).
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In addition to a remodelling of the mine building, a new shaft was sunk in 1959. It descended to the 15th level at a depth of 460 metres; 80 metres deeper than before. Three existing shafts were thus replaced by it. Above ground, a treatment plant with crushers and a flotation facility were built.
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The school building lies on the grounds of the former Llwyn Hall that was demolished. The school was built in the 1950s to replace an earlier building and was considerably extended in the early 1970s. The school completed a £2.2 million extension and remodelling programme in 1998 providing a high standard of accommodation and resources.
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A number of housing subdivisions have also been initiated, as well as rural residential subdivision on the fringes of the town. The construction of a freeway bypassing Drouin allowed the remodelling of the shopping centre. By 1981, the population was 3,492 and in 1991 was 4,100. The Victorian Municipal Directory described the town in 1994.
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The deposition then influences the airway remodelling in asthmatic patients. Dupilumab is a monoclonal antibody IL-13 and IL-4 modulator that targets the shared receptor of IL-4 and IL-13, IL4Rα. Since IL-4 and IL-13 have similar biological activities, dupilumab may be an effective form of treatment for asthmatic patients.
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This remodelling was carried out by J Anthony Lewis of architects Michael Tapper & Lewis, who commissioned the sculptor Don Potter to create "The Four Evangelists" on the outside of the building (c.1957). Potter also created a font in Clipsham stone.Light (2002), p.166Lewis and Don Potter also worked on St Matthew Bethnal Green.
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Cancer Biother. Radiopharm.32, 327–334 (2017). Expression of ETS1was increased in cancer tissues as compared with the expression in corresponding non-neoplastic tissues. Finally, USF is an upstream stimulating factor, which is involved in mediating recruitment of chromatin remodelling enzymes and interacting with co-activators and members of the transcription pre-initiation complex.
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Within the Kennedy Centre, there is currently 48 stores. Some of these stores include Iceland, Costa Coffee, Greggs and 26 West Bar & Grill. Other stores include Boots UK, Peacock, O'Neills, DV8, JD Sports, Home Bargains, CEX & Poundland. Post-remodelling, the Kennedy Centre now hosts a foodcourt in the upstairs area opposite the Omniplex cinema.
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In 2016 the purchase went ahead, and detailed redevelopment plans were drawn up during 2017 and the planning application for the redevelopment was approved by Bath and North East Somerset Council in September 2017. Remodelling and refurbishment was again designed by Grimshaw Architects, and the building was opened as the Locksbrook Campus in October 2019.
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This interaction is vital in controlling the local immune systems which in turn is vital for maintaining a semi-allogeneic fetus. At the end of gestation, a 'weak zone' develops in the foetal membrane overlying the cervix due to collage remodelling. This eventually leads to rupture of the fetal membrane and the onset of labour.
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Adriaen van Stalbemt's A View of Greenwich, c. 1632. Royal Collection, London. James I carried out the final remodelling work on Greenwich Palace, granting the manor to his wife Queen Anne of Denmark. In 1616 Anne commissioned Inigo Jones to design and build the surviving Queen's House as the final addition to the palace.
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As a result, he is often overlooked today, remembered principally for his Palladian remodelling of numerous country houses, many of them situated in the East Anglia area of Britain. As Brettingham neared the pinnacle of his career, Palladianism began to fall out of fashion and neoclassicism was introduced, championed by the young Robert Adam.
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The response of naked carp to cold and low-oxygen conditions seem to be at least partly mediated by hypoxia-inducible factor 1 (HIF-1). It is unclear whether this is a common characteristic in other high altitude dwelling fish or if gill remodelling and HIF-1 use for cold adaptation are limited to carp.
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The dome is large enough to fit the Leeds Corn Exchange under it. Major works started at Trinity West in 2011 to remodel the centre's interior. Boar Lane Bus Point closed to create a new pavement and external remodelling involved removing cladding. A tower crane facilitated upward extensions to accommodate the flagship Primark store.
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Technological developments in the twentieth century enabled scientists to analyse the chemical changes in the plaque biome from healthy to diseased environments, which then brought several problems to light. The recently posited keystone-pathogen hypothesis holds that certain malignant pathogens can control the inflammatory disease by proliferating, remodelling and disproportionate a normally benign microbiome.
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In 1247, the church had its first priest, and in 1519, it acquired its first bell. In 1609, a massive fortress church was built in the Romanesque style with defensive towers, parapets and battlements. Between 1895 and 1897, the church underwent remodelling, giving it its current appearance. In 1949, the church acquired four bells.
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The recuperation of the windmills was only possible after the original property-owners had ceded the structures to the municipality for five years.Associated with this remodelling project, the village of Corvo had also purchased a small whaling launch from Graciosa, which was recuperated and transported to the parish, to preserve the island's whaling tradition.
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By 1959 the Coins and Medals office suite, completely destroyed during the war, was rebuilt and re- opened, attention turned towards the gallery work with new tastes in design leading to the remodelling of Robert Smirke's Classical and Near Eastern galleries.Wilson, David, M. (2002). The British Museum: A History. London: The British Museum Press, p.
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George Webster (1797–1864) was an English architect who practised in Kendal, Cumbria. He worked mainly in domestic architecture, designing new houses, and remodelling older houses. His early designs were mainly in Neoclassical (Greek Revival) style. He later pioneered the use of the Tudor Revival style, and in some of his latest designs he incorporated Italianate features.
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The walls were constructed in brick- faced concrete, thick and high, with a square tower every 100 Roman feet (). In the 5th century, remodelling doubled the height of the walls to . By 500 AD, the circuit possessed 383 towers, 7,020 crenellations, 18 main gates, 5 postern gates, 116 latrines, and 2,066 large external windows.Claridge, Amanda (1998).
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The inventory of equipment includes automotive, bike, carpentry and woodworking, electrical and soldering, home maintenance, metalworking, plumbing, remodelling, yard and garden, Electronics and Kitchen. The types of equipment include: garden tools, kitchen tools, hand tools, and power tools. The OTL is seeking cash donations as well as: hand tools, power tools, garden tools and kitchen tools.
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Sir Henry married Alice Pye of the Mynnd. (Both were later interred in the Church at Stoke Edith but during remodelling of the Church their monuments were lost). With the Restoration he became a member of parliament for Herefordshire but died of smallpox in Gloucester on his way back from a sitting in London in 1662.
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Hoskins, p.338 John Widgery, 1st Baron Widgery Grilstone in the parish of Bishop's Nympton in north Devon, England, is an historic estate. The present grade II listed house, situated about 1 1/4 miles south-east of the market town of South Molton, is Georgian, an 1834 extension and remodelling by Rev. William Thorne of an earlier building.
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In 2015 the front of the theatre underwent a £1m refurbishment which included the complete remodelling of the front of house areas, the introduction of a coffee shop and the installation of a lift to the first floor bar. The refurbishment also included the redecoration of the auditorium, which had not been renovated since the early 1990s.
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Pier forecourt with the protected sculpture of Vater und Sohn ("Father and Son") The remodelling of the pier forecourt was carried out in phases. The Kopfsituation, with its Forum and Bastion, was built in 1992. The forecourt was designed in 1991. The running area (Laufachse) and ramps, the pavements and the play area (Spielachse) were added in 1995.
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Anton Erhard Martinelli (1684 – September 15, 1747) was an Austrian architect and master-builder of Italian descent. Martinelli was born in Vienna. He was the son of architect Franz Martinelli. Anton Erhard Martinelli supervised the construction of several important buildings in Vienna, such as the Karlskirche and the Palais Schwarzenberg or the remodelling of the Deutschordenskirche.
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The tower rises in three stages, of which the lower two are supported by corner buttresses. Above these, there is a belfry stage with lancet and round windows. A prominent parapet separates the belfry from the spire. Inside, the 12th-century arcades show some remodelling, and the capitals at the top of the piers may be entirely Burton's work.
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Tendon, as a tissue is mechanoresponsive. Various academic studies show that tendons can respond well to controlled loading, post-injury. Loading of a tendon results in up regulation of insulin-like growth factor, in addition to other cytokines and growth factors. This up regulation results in proliferation at the cellular level and remodelling of the tendon matrix.
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It incorporates an effigy executed by Henry Apperley (1824-1887). Patteson had visited Christ Church on several occasions. Blacket was a parishioner of Christ Church from 1848, serving as churchwarden for 22 years (1851-1873). Blacket's sons were responsible for remodelling the sanctuary and chancel in 1884–5 to reflect the parish's adoption of Anglo-Catholic liturgy.
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ET receptors are G protein coupled receptors and, when activated, lead to an increase in intracellular calcium levels via the Gαq signaling pathway. The rise in intracellular calcium leads to contraction of the arterial smooth muscle, as well as vascular remodelling due to cell proliferation. Prolonged constriction and fibrosis are factors in the pathogenesis of PAH.
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Shaw worked with Humphrey Repton, remodelling Lord Uxbridge's property at Beaudesert, and was later employed to redesign parts of Newstead Abbey in Nottinghamshire by Colonel Thomas Wildman who had just bought the estate from Lord Byron. Between 1821 and 1826 he rebuilt Ilam Hall in Staffordshire in the Gothic style for the manufacturer Jesse Watts Russell.
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Crowd at the Estadio Nuevo Arcángel Match of Segunda División between Córdoba C.F. and C.D. Leganés (2:3), January 2016. Córdoba currently plays at the Estadio Nuevo Arcángel, opened in 1993. Since 2004 the stadium has been going through a remodelling, converting it to a pure football stadium. Three of the four sides have been rebuilt.
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Wolryche-Whitmore continued to support liberal political campaigns after leaving parliament, particularly the Anti-Corn Law League. His wife died in 1840. He spent heavily on remodelling the house and the estate on more modern lines, diversifying the economic activities and improving conditions for his workers and tenants. He left mortgages totalling £60,000 to his nephew, Rev.
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FSTL1 protein seems to have a cardioprotective role. FSTL1 attenuated hypertrophy following pressure overload and prevented myocardial ischemia/reperfusion injury in a mouse or pig model of ischemia/reperfusion. Muscle-derived Fstl1 modulates vascular remodelling in response to injury. FSTL1 has been shown to have a pronounced ability as a possible therapeutic to stimulate regeneration following myocardial infarction.
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The local church is dedicated to Saint Anthony of Padua and belongs to the Parish of Preloka. It was first mentioned in written documents dating to 1526, but owes its current Baroque look to a remodelling in the 18th century. In 1888 it also underwent a major rebuilding. The main altar dates to the late 19th century.
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The Bliss Institute in Belize City after its remodelling in 2003 The Bliss Institute is a theatre, museum, and National Arts Council in the cultural centre of Belize City. It is named after Baron Bliss. The original construction started in 1953 and finished one year later. The architectural design was done in a modernist international style.
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Kenton Couse (1721 – 10 October 1790) was an English architect. He was apprenticed to Henry Flitcroft whose patronage obtained him posts in the Office of Works. Couse subsequently became Secretary to the Board of Works from 1775 to 1782. His most famous work as an architect was the remodelling of 10 Downing Street from 1766 to 1775.
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Ljubljana: Državna založba Slovenije. p. 21. The local parish church is dedicated to Saint Nicholas () and belongs to the Roman Catholic Diocese of Novo Mesto. It was first mentioned in written documents dating to 1334, but owes its current Baroque look to a major remodelling in the second half of the 18th century. The main altar dates to 1782.
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The house is built of rubble limestone with roughcast render and a stone slate roof. It is a two-storey building with attic and cellar. The house of 1590 had a three-room plan but later additions in the seventeenth century and around 1780 enlarged this, and internal remodelling was done in the late nineteenth and early twentieth centuries.
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Katia Dandoulaki has a theatre named after her in Athens. The modern theatre of Katia Dandoulaki resulted from the remodelling of the third floor of a commercial complex of entertainment halls built in the 1960s. In particular, the 1000 m2 area of the Superstar Theatre was completely remodelled. It is a work by architect Katerina Thanou.
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Lally has published over 50 papers, receiving over 1800 Citations. Her research focuses on arterial tissue mechanics, vascular imaging, vascular mechanobiology and tissue engineering. In 2014, she secured an ERC (European Research Council) Starting Grant for a five-year €1.5m project that will advance research in arterial fibre remodelling for vascular disease diagnosis and tissue engineering.
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During the remodelling of the chapel, Archbishop Diogo de Sousa also commissioned a stone altar, but most of it has been lost. The part still preserved is used as altar table and has beautiful reliefs of Christ and the Apostles. The choir stalls are neogothic. The other chapels of the apse are decorated in baroque or neoclassical styles.
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Clinical Calcium, 16(10), 1632. Direct effects have been identified between MBP and strengthening of bones, through its influences on bone remodelling (formation and resorption) and enhancement bone mineral density. These actions may be beneficial for pre-menopausal and menopausal women in particular, as increased bone mineral density decreases the risk of fractures associated with osteoporosis.
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The plans for an atmospheric auditorium were very much like Eberson's Riviera at Omaha, Nebraska. The conversion involved remodelling the interior and raising the roof trusses to make room for the atmospheric ceiling and extended slope of the new gallery. In May 1927, the Sydney City Council approved Wirth's proposed alterations. The Capitol opened on 7 April 1928.
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He renamed the building Denville Hall and created a charity in the same name. It was opened formally as a rest home in July 1926 by Princess Louise, the then Princess Royal. The building, heavily extended in the intervening years, is locally listed. A further remodelling and expansion project with landscaping, by Acanthus LW Architects, was completed in 2004.
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Verdi's Macbeth was given its premiere performance at the Pergola in 1847. The Pergola's present appearance dates from an 1855–57 remodelling; it has the traditional horseshoe-shaped auditorium with three rings of boxes and topped with a gallery. It seats 1,000. It was declared a national monument in 1925 and has been restored at least twice since.
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József Hild (born as Josef Hild, , 8 December 1789 in Pest – 6 March 1867 in Pest) was a Hungarian -German architect.Hild József, Hungarian Electronic Library, retrieved 11 May 2012 One of the major exponents of neoclassical architecture of the time, he played an important part in the remodelling of Pest during the so-called reform era (early 19th century).
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The unit was supposed to be ready on 20 November, but delays occurred. At that time Tyrconnell's remodelling of the Irish army had advanced so far that few units still had significant numbers of Protestant soldiers. One of those was the regiment of Viscount Mountjoy, a Protestant loyal to James. This unit was in garrison at Derry.
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The maxillary sinusitis as evidenced by the amount of lesions and remodelling on bone are suggestive of chronic infections. Though not generally of cause of death on its own, the prevalence of maxillary sinusitis did predispose the Moatfield inhabitants to other respiratory infections such as tuberculosis, which was found to be a common cause of death.
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The two wings post-date May's frontage, being of the late 18th century. The roof is of slate with a parapet, and the house is of two storeys, with cellars and attics. The interior contains two rooms which retain the original decorative schemes from May's time, the drawing room and the hall. The rest date from Sarel's remodelling.
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As a result, the Adventists built Florida Hospital Heartland Medical Center in Sebring, which opened in 1997. The old Walker Hospital remained vacant, although at least two remodelling projects were considered. In 2004 the building was severely damaged by the triple blows of Hurricanes Charley, Frances and Jeanne. Another hurricane passed over the area in 2005.
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The noted theatrical architect Frank Matcham was engaged to build the new Empire Palace of Varieties next door. The Theatre Royal was closed between the end of April and September 1897 for remodelling. The works included building new dressing rooms at the rear to clear part of the site for the Empire. Matcham also refashioned the existing auditorium.
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Other large crusader castles were also surrounded by great Zwinger systems. The outer ring wall of the castle of Tartus (Syria) could have been built at the same time as the Zwinger at Krak, i.e. in the middle of the 13th century. By shortly before 1168 the Knights of St. John began remodelling Belvoir Castle in present-day Israel.
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Vickroy, Donna. "Throwing the book at library scofflaws," Southtown Star (Chicago). February 1, 2009. The house has remained largely untouched, having remained "unimproved" despite the Victorian passion for remodelling and redecorating, due to the fact that for most of the 19th century the family lived mainly at Cholmondeley Castle in Cheshire, and only stayed at Houghton for the shooting.
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He was murdered in Los Angeles in September 1929. Ada McDonald, sister of the McDonald boys, became a premier receiver of stolen goods. According to Detective Superintendent George Cornish of Scotland Yard, she provided services for five major London gangs, including the Forty Elephants. She specialised in fencing expensive furs for remodelling by East End tailors.
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One hundred half- timbered buildings were torn down as part of this renovation and were replaced by new buildings that were not always agreeable. The remodelling did, however, contribute to improving the town's economic situation considerably. Frankenberg has become a shopping town, inviting people to take a walk and visit the Old Town and New Town.
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The gardens of the Buen Retiro stretched to the Paseo del Prado. The so-called gardens of San Juan seemed to be the site for the construction of the new building. The architect José Grases Riera had previously carried out studies for the remodelling of the area and had one of them published.Grases Riera, José (1905).
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He also intended the zoo to be cheaply and quickly accessible via public transport. The society secured an option to purchase the Corstorphine Hill House estate for £17,000. The house had been built in 1793 as the home of Scottish accountant William Keith. Its current Scottish Baronial architecture is mostly thanks to remodelling by the Macmillan family in 1891.
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Formosa Boulevard () is a station of Kaohsiung MRT located in Sinsing District, Kaohsiung. It is the sole interchange station between metro lines in Kaohsiung. Formosa Boulevard station is named after the Formosa Boulevard project, a remodelling of Kaohsiung's Jhongshan Road in preparation for the 2009 World Games. Formosa Boulevard is in turn named after the Formosa Incident.
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The arena floor has an area of . The flooring material was originally beechwood, but it was replaced in 2013 with palmate maple. Jeonju Gymnasium is the only large-scale indoor sports arena in the city, though there have been multiple proposals to build a second one. Despite the remodelling, public perceptions of safety issues in the gymnasium have persisted.
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Further afield his works included workhouses at Calne, Wiltshire (1847) and in Liverpool, design of the William Brown Library also in Liverpool, (1857–1860), and the tower of St. Leodegarius Church, Basford near Nottingham (1860). He also worked with Sir Charles Barry on numerous projects, including the Houses of Parliament and the remodelling of Highclere Castle.
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The bronchoalveolar lavage (BAL) fluid of patients with idiopathic pulmonary fibrosis contains a higher concentration of ATP than that of control subjects. Persistently elevated concentrations of adenosine beyond the acute-injury phase leads to fibrotic remodelling. Extracellular purines modulate fibroblast proliferation by binding onto adenosine receptors and P2 receptors to influence tissue structure and pathologic remodeling.
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The Community Centre, along with a new library, including a toy library for children was opened by Princess Alexandra in November 1973 in Whitehawk Road. At the time it was the largest in Brighton. From 1975, the Council started a remodelling exercise in Whitehawk. Initially, houses were left empty as they became vacant, and were boarded up.
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The current building dates from the end of the 19th century, with the first stone placed in 1893. Known originally as the Torres de Meirás, it was built on the ruins of an old military fortification, built on land owned by the Patiño de Bergondo since the 16th century, that had been destroyed by Napoleonic French troops in 1809 during the Spanish War of Independence. Through marriage, the property was transferred to the Pardo de Lama, and then through direct inheritance to the writer Emilia Pardo Bazán, who undertook major remodelling to create the current building layout. The writer married in the chapel - which she called "Granja de Meirás" - 5 on 10 July 1868 and, once the remodelling was complete, spent more than four months there every year.
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It was not until 1783 that Soane received his first commission for a new country house, Letton Hall in Norfolk.Darley, 1999, pp. 64–65 The house was a fairly modest villa but it was a sign that at last Soane's career was taking off and led to other work in East Anglia: Saxlingham Rectory in 1784, Shotesham Hall in 1785,Darley, 1999, p. 68 Tendring Hall in 1784–86,Stroud, 1984, p. 124 and the remodelling of Ryston Hall in 1787.Stroud, 1984, p. 131 Bank of England Entrance facade, 1818–1827 At this early stage in his career Soane was dependent on domestic work, including: Piercefield House (1784), now a ruin;Stroud, 1984, p. 138 the remodelling of Chillington Hall (1785);Stroud, 1984, p. 246 The Manor, Cricket St Thomas (1786);Stroud, 1984, p.
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The hall consists of a central block of three storeys flanked by two pavilions, both of two storeys. The building is built in the neo-classical style, with the central block featuring a large pediment. The majority of the work is in brick, with stone dressings. There is some evidence that the upper floor may have been rebuilt during extensive 19th century remodelling.
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The pediment has a central lunette, and each side consists of two bays in which the windows have wide flat surrounds. There are four parapet vases. The steps originally had low flank walls perpendicular to the facade, which were removed in the later remodelling. On the southeast facade, the centre has a Doric temple front with open pediment, which surrounds the doorway.
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At the time of its opening, all Argyle Line trains towards Uddingston and Bellshill stopped at Newton. Since the 1990/91 remodelling Argyle Line trains toward Bellshill no longer stop at the station. Shotts Line services via and Intercity services pass the station on the main lines. The 2010/11 service had most trains passing through the station without stopping.
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Scientists Turn Skin Cells into Heart Cells and Brain Cells Using Drugs. Gladstone Institutes. News Center In another study, ischemic cardiomyopathy in the murine infarction model was targeted by iPS cell transplantation. It synchronized failing ventricles, offering a regenerative strategy to achieve resynchronization and protection from decompensation by dint of improved left ventricular conduction and contractility, reduced scarring and reversal of structural remodelling.
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The museum is located in the old residence of Pere Turull i Sallent, a well-known industrialist from the textile era of the city and co-founder of the Caixa d'Estalvis de Sabadell savings bank. The building was constructed between 1812 and 1819 and was purchased by the Sabadell Town Council in 1964. It underwent remodelling between 1993 and 1997.
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The operational part of the station is being remodeled as well; the old signal box has been recently replaced with an electronic signal box. This was vital to improve capacity of the station. The new signal box became operational in late 2005 and will allow faster speeds into the station (up to 60 km/h) after the remodelling of the tracks.
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Following this remodelling, the St. Sunniva entered service as a mail steamer on the Lerwick route, operating a weekly service from Leith and Aberdeen. She remained on this demanding service until 10 April 1930 when, while sailing north in fog, she ran aground on the uninhabited island of Mousa, Shetland. All passengers and crew were rescued but the ship was a complete loss.
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The building that houses the museum was built by a Lisbon lawyer, Augusto Vítor dos Santos, in 1896. In 1921, it was sold to Eduardo Guedes de Sousa who added the two upper floors. In 1927 it was sold to the Vatican to become the Apostolic Nunciature. Medeiros e Almeida and his wife purchased it in 1943, moving into it after extensive remodelling.
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The full circuit ran for surrounding an area of . The walls were constructed in brick-faced concrete, thick and high, with a square tower every 100 Roman feet (). In the 4th century, remodelling doubled the height of the walls to . By 500 AD, the circuit possessed 383 towers, 7,020 crenellations, 18 main gates, 5 postern gates, 116 latrines, and 2,066 large external windows.
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Heat shock serpin 47 is a chaperone, essential for proper folding of collagen. It acts by stabilising collagen's triple helix whilst it is being processed in the endoplasmic reticulum. Some serpins are both protease inhibitors and perform additional roles. For example, the nuclear cysteine protease inhibitor MENT, in birds also acts as a chromatin remodelling molecule in a bird's red blood cells.
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In 1997 extensive work was done on the church's exterior. Moreover, the rectory and sacristy were remodelled. In 2006 came a radical renovation and remodelling of the church's interior. A decisive architectural feature resulting from this is the shifting of the altar from the sanctuary forwards to the centre of a half-circle consisting of four segments, made out of old pews.
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97-98 The square house seen today is a Georgian remodelling of the first house by Hugh Percy, 1st Duke of Northumberland (1714–1786), in about 1760. The first Duke was born Hugh Smithson, and married Lady Elizabeth Seymour (daughter and heiress of Algernon Seymour, 7th Duke of Somerset (d.1750), a direct descendant of Protector Somerset), whose grandmother Lady Elizabeth Percy (d.
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After Gorakhpur, and Kollam junction in Kerala, Kharagpur has the world's third longest railway platform with a length of . Remodelling of Gorakhpur railway station was completed and the new platform inaugurated on 6 October 2013. Till then Kharagpur boasted of the longest platform in the world for many years. Kharagpur also has the Asia's largest Railway Solid State Interlocking (SSI) system.
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In 1479, the provincial governor Půta Švihovský of Rýzmberk became the owner of the estate and began with a thoughtful remodelling of the castle under the guidance of famous master Benedict Rejt. New living quarters and service buildings were constructed, the castle was enlarged and the fortifications heightened. Rabí Castle was, from the very start, envisioned as a donjon-type castle.
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75, It was later modified by comprehensive Late Gothic remodelling by the Lords of Donin.Klára Benešovská (2001), Architecture of the Gothic, Prague Castle Administration, p. 211. In 1518, during the reign of Bořitas of Martinice, the castle was turned into a residence in the Renaissance style. During the Thirty Years' War the castle was heavily damaged and then restored in the Baroque style.
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However, a complete renovation of the station would be necessary after this "small solution" was carried out. Planning for more extensive remodelling continued. In 1957, the construction of a second Ringbahn platform west of the existing platform to relieve congestion was considered. In 1959, it was announced that the reconstruction of the railway station would begin in 1962 or 1963.
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The present tower was designed by French architect Gastón Lelarge, the result of remodelling in the early twentieth century. Construction began in 1577, replacing a humble cathedral of straw and reeds. In 1586, while the church was still under construction, it was attacked by the English privateer Francis Drake, which caused severe damage and delayed its completion. The building was finished in 1612.
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Adams & Kelly employed, as an assistant, John Leeming (1849–1931), who in 1872 went into partnership with his brother Joseph as Leeming & Leeming, and was responsible for the partial remodelling of the interior of Kinloch Castle on the Isle of Rùm in Scotland. In 1886, three years after the death of Adams, Kelly went into partnership with Edward Birchall as Kelly & Birchall.
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Binding of growth factors is clearly an important role of perlecan in wound healing and angiogenesis. Poor wound healing in diabetes mellitus may be related to perlecan expression. High levels of glucose can decrease perlecan expression in some cells probably through transcriptional and post- transcriptional modification. Wound healing phases especially, granulation, re-epithelization and remodelling exhibit controlled turnover of extracellular matrix components.
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A Pioneer's memorial was erected on Big Hill in 1938. The town hall underwent significant postwar remodelling, culminating in the addition of the landmark clock tower in 1939. The Quartz Gold Memorial and Dane Memorial seat were erected on Big Hill in 1953 out of local quartz stone. Stawell's historical association with gold-mining was revived when full-scale mining recommenced in 1981.
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Now in working condition and repainted in BR green, it was regularly used to haul normal passenger trains in the hope of attracting enthusiasts, as well as special trains. In addition, four locomotives were temporarily returned to service as Class 97 departmental locomotives, numbered 97 405–408. They were used to work engineering trains for a remodelling project at Crewe station.
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Bodrhyddan Hall is a country house in Rhuddlan, Denbighshire, Wales. It is a Grade I listed building. The present building is a 1690s remodelling of an earlier building dating from the 16th century. It was later upgraded by the architect William Eden Nesfield, who in 1875 added a new west facing entrance front and a service wing and refaced the east front.
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The larger windows on the lower level were topped by pediments with shell design. The southern and northern side doors had red marble frames decorated with crosses. A few old gravestones were immured into the outer walls. The facades were enriched by the Neo-Baroque remodelling with new decorative elements like the heavy cornice and the railings of the balconets.
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In response to oxygen levels 95% lower than normoxic conditions, apoptosis of ILCM increases lamellar surface area by up to 60% after just 24 hours. However, this comes at a significant osmoregulatory cost, reducing sodium and chloride levels in the cytoplasm by over 10%. The morphological response to hypoxia by scaleless carp is the fastest respiratory surface remodelling reported in vertebrates thus far.
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Conradin Kreutzer Monument Western aspect seen from the Hofgarten Plan of the second storey around 1820 The castle's origins go back to around 1400. Froben Christoph von Zimmern reported in the Zimmern Chronicle on the remodelling that his uncle, Gottfried Werner had carried out to the old castle beginning in 1520. These measures come in for heavy criticism.Zimmern Chronicle, Vol. 4, p. 148.
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When diplomatic relations between the US and China fizzled out, it was turned into a low-rent apartment building. When they tried to evict the residents to raise the rents, they were sued, leading to a US$1.7 million settlement. It is owned by the Chetrit Group, chaired by Joseph Chetrit. They have been remodelling it into a hotel since 2012.
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The courtroom was remodelled after World War II. More recent remodelling in 1973-1974 included an enclosed counter on the main floor hallway. The jail has been moved to a separate structure. The long twin stairways, one on each end of the main hall, have not been modified. These curving wood stairways with their ornamental stringers are in excellent condition.
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Asgard members encode many eukaryotic signature proteins, including novel GTPases, membrane-remodelling proteins like ESCRT and SNF7, a ubiquitin modifier system, and N-glycosylation pathway homologs. Asgard archaeons have a regulated actin cytoskeleton, and the profilins and gelsolins they use can interact with eukaryotic actins. They also seem to form vesicles under cryoEM. Some may have a PKD domain S-layer.
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The human body is in a constant state of bone remodeling.Guyton and Hall Textbook of Medical Physiology, 12th Edition. Bone remodelling is a process which maintains bone strength and ion homeostasis by replacing discrete parts of old bone with newly synthesized packets of proteinaceous matrix. Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification.
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A 1778 report recommended alterations to the blockhouse and its defences, leading to the remodelling of the gun platforms and the construction of the new, larger New Tavern Fort alongside it. In the 1830s the government decided to rely entirely on the newer fort and the old blockhouse was demolished in 1844. Its remains were uncovered in archaeological excavations between 1975 and 1976.
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Casa Bonet was built in 1887 by Jaume Brossa and was known as the Casa Torruella. In 1915, Delfina Bonet commissioned the architect Marcel·lí Coquillat to redesign the facade, remodelling it in an Italianate Neo-Baroque style with a two-storey loggia and neo-baroque ornamental details decorating the upper floor lintels. Today the building is occupied by the Barcelona Perfume Museum.
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The remodelling by Humphrey Sturt involved moving the village of Moor Crichel a mile to the south and many of the villagers were moved to Witchampton. This was so that the parkland could be landscaped and the original site of Moor Crichel is now submerged beneath the lake. Humphrey Sturt stopped short of moving St Mary's Church, which remains today.
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When the scheme was first proposed, the golf club was one of the main objectors to it, as it would require alterations to the 16th and 17th holes, and during a flood event, when water from the beck was impounded in the reservoir, three further holes would be under water. However, agreement was reached on remodelling the golf course following consultation.
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Between 20 July and 25 August 2013, the services from the station were reduced because of the Nottingham remodelling and resignalling scheme. It acted as a terminus for trains from London via East Midlands Parkway and from Derby, with a frequent rail-replacement shuttle bus running to and from Nottingham while the western end of the station and approach lines were remodelled.
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The alterations included an almost complete remodelling of the interior and the replacement of the Gothic Revival pointed arch windows with new round arched stained glass replacements. Having outgrown the original building by the 1960s, the congregation had a new 687-seat capacity sanctuary constructed adjacent to the original. It was built to the designs of Montgomery architect Tom B. Kirkland.
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Logan, 1983 75 architectural drawings prepared for William Wyndham between 1812 and 1817 have been located in the drawings collection of the Royal Institute of British Architects at the Victoria and Albert Museum in London. Drawings prepared for William Wyndham between 1812 and 1817. They include the initial proposals for remodelling the Dinton house, by architect Jeffry Wyatt (later Sir Jeffry Wyatville).
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The Congregationalists recommended the appointment of Trevor Dannatt, the architect who had been responsible for the remodelling of their church in 1957. Ted Happold of Ove Arup was the structural engineer. Dannatt (a Congregationalist) and Happold (a Quaker) had recently worked together on the new assembly hall (also Grade II listed) at Bootham School. The job architect was David Greenwood.
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Warnford Place is a country house, southeast of the church, with grounds overlooking the River Cole. One wing of an 18th-century house survives, following remodelling by Lord Banbury in 1904. The house, then known as Sevenhampton Place, was owned by Ian Fleming and his wife Ann from 1960 until her death in 1981. Central Hall Cricket Club is based in the village.
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Roope went bankrupt in 1800; Burdett opines that this could have been because of the amount of money spent on rebuilding Greenway. 1854 Ordnance Survey map showing the house at Greenway The Elton family developed the garden, with some remodelling by the landscape gardener Humphry Repton. At some point in the late 18th century the Tudor house was entirely demolished.
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This home is separated into 14 rooms and six common areas, in which various new art pieces and decorations are showcased. The remodelling in 2010 added specific studied reproductions of the original family's artefacts. The wallpaper, the kitchen, the bathroom, and bedroom closet were remodelled. Stuffed wolves found in the family's archives are now placed at the entryway of the museum.
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Dictionary of Ohio Historic Places. Vol. 1. St. Clair Shores: Somerset, 1999, 26. Austin's house is a brick structure in the Italianate style. Its appearance is radically different from that of its earliest years; it appears that the present appearance was the result of an extensive remodelling project conducted under the auspices of Austin's grandson Louis B. Austin during the 1860s.
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The area became the focus of a targeted regeneration initiative, led by the Castle Vale Housing Action Trust (CVHAT) from 1993 to 2005, where the estate witnessed the demolition of many of its housing stock and facilities, the refurbishment of remaining properties, and the construction of new housing and facilities along with the remodelling of the estate, funded both privately and publicly.
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The successful tenderer was the firm of Charles Davis and Son, which submitted the lowest tender of 82,927 pounds. Among the firm's larger contracts were the AMP block, remodelling of the Council's market street buildings, the Commercial Bank, and several hotels including the Crown and Anchor. His domestic work included Braeside at Waratah, designed by Frederick Menkens.Conservation Management Plan, pp.
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Sorn Castle He was born in Glasgow on 21 July 1896, the son of Thomas McIntyre and Jeanie Paterson. He had three sisters. His father purchased Sorn Castle in 1908 and began remodelling it in 1909. His father owned a shipping line and was Chairman of Lloyds Register but abandoned many of his business activities to concentrate on the estate.
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He was the son of Hugh Cholmley MP and his wife Catherine, the daughter of Sir John Wentworth, 1st Bt. He was elected to Parliament for the constituency of Aldborough from 1756–1768 and for Boroughbridge from 1768–1774. He commissioned the remodelling of his seat at Howsham Hall in North Yorkshire, employing Capability Brown to lay out the parkland.
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In the early 20th century a five-storey addition was built, completely enclosing the southeastern tower. The castle fell into a state of dereliction by the 1960s, but it was renovated for use as a private family home from about 1968–1998 by a series of owners. As part of the remodelling, all of the external additions, except for the office, were demolished.
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He was responsible for the remodelling of Capel Als, Llanelli. Secular buildings produced by his firm include the Albert Hall, Llandrindod Wells. Many of his chapels are in the Italianate style, occasionally freely mixed with Classical elements, and often feature stair towers. Roberts, who was a prominent member of the Liberal Party and a councillor for Merioneth, died in Porthmadog in 1896.
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1890 The interior has relatively modest Federal styling, most of which it has retained. The original pulpit and box pews remain, although the doors of the latter have been removed. The balcony level was removed during remodelling in 1902. Major settlement of the town of Bingham began in the early 19th century, with early church congregations meeting in the local schoolhouse.
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She was skilled at architecture, watercolor; engraving; designing objects of ivory and amber; and horticulture. The palaces of Pavlovsk, Gatchina, Tsarskoe Selo, the Winter Palace in St. Petersburg and The Hermitage were remodelled and furnished under her personal guidance. Her efforts would produce some of the most beautiful estates in all of Russia. Maria Fedorovna and Paul began remodelling Pavlovsk.
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The interior of the house is well preserved despite extensive remodelling in the 20th century. It has original doors and door hardware, including latches and strap hinges of wrought iron. The narrow entry hall includes a winding staircase with original handrail, balustrade, and newel post. In the older rear ell, the heavy post and beam framing is exposed in many places.
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Other than this, the Chapel has remained unchanged for over 800 years. Bishop Robert Sherborne undertook major construction projects at the Palace, including the remodelling of the south-west and south-east wings. Bishop Sherborne also had a wing built to the north of the west end. Bishop Edward Waddington restored the Palace from a supposedly ruinous condition in 1727.
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John Archibald, the proprietor of the Dominion Milling Company and a Member of the Queensland Legislative Council. After Archibald's death in 1907, it remained the home of his widow until 1929. In May 1929, the Archibald family gave Glenugie to the Presbyterian and Methodist Churches for use as a girls hostel known as Archibald House. After some remodelling, the hostel opened in July 1930.
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A stone church was mentioned as standing on this site in c. 973. The 1086 Domesday Book recorded the church, on land held by Westminster Abbey. Small amounts of Anglo-Saxon stonework survive in the present building, in particular in the south wall of the nave. The north arcade was added in the late 12th century, while the south arcade is from a remodelling in the 13th.
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The Laird's House The fine Georgian dwelling house was built in 1782-4 and cost £45.12.7, not an inconsiderable sum for the time, paying for a Laird's home of almost miniature classical country house appearance. An extension to the house was built in 1906 allowing for remodelling of the interior layout. Electricity was installed in the 1950s, replacing the use of oil lamps and candles.
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In 1841 appeared Ogle's only publication, A Letter to the Reverend the Warden of Wadham College, on the System of Education pursued at Oxford; with Suggestions for remodelling the Examination Statute. This pamphlet made the first suggestion of a natural science school at Oxford, established by a statute brought forward in 1851. He anticipated also a change, by his proposal for an admission examination.
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The design on the torc can be studied easily by imagining the hollow tube as straightened and flattened. This was done in the first study of the hoard by Arthur Evans and his drawing can be seen here. The design matches other Irish pieces, and may have been a remodelling of a plainer British or Rhineland torc (the Rhineland is one possible source of the gold).
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Int J Biochem Cell Biol 1999. 31:395–403Swaney JS, Roth DM, Olson ER, Naugle JE, Meszaros JG, Insel PA. 2005. Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase. Proc. Natl. Acad. Sci. U. S. A. 102:437–442 TGF-β1 plays an important role in cardiac remodelling through the stimulation of fibroblast proliferation, ECM deposition and myocyte hypertrophy.
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The SOAS Centenary Masterplan conceived the development of two new buildings and a substantial remodelling of existing space to realign and develop the entrance and two areas within the Old Building. The cost estimates for the Centenary Masterplan settle at around £73m for the total project. The full implementation of the School's Centenary Masterplan would deliver approximately 30% additional space, approximately 1,000 sq metres.
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The arch to the stable block is dated 1807. The bay window was added in 1833 and in 1841 the Edward Haycock took over as architect, remodelling the interior after a fire and adding a Neo-Norman porch to the rectangular tower. He continued expanding the house until 1867. The work was for the Rogers family who followed Thomas Johnes of Hafod as the owners of Stanage.
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Both the front and rear facades are all-header bond, while the remaining sides are English bond. The present roof form was built in 1894 during a significant remodeling. The large brick wing to the rear was an addition that replaced a wooden structure during the 1894 remodelling, as was the addition of the roof-top balustrade. The interior features a central hall plan.
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Trentham Hall, demolished A major focus of his career was the remodelling of older country houses. His first major commission was the transformation of Henry Holland's Trentham HallGirouard, P.422 in Staffordshire, between 1834 and 1840. It was remodelled in the Italianate style with a large tower (a feature Barry often included in his country houses). Barry also designed the Italianate gardens, with parterres and fountains.
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On 21 April 1935, celebrations marking the 20th anniversary of the Theatre Circo was inaugurated. Similar festivities were celebrated on 21 April 1940, marking the silver anniversary of the institution, that include performances by tenor Ascenso de Siqueira Freire. Between 1943 and 1950, the prosperity of the theatre reached its peak, and were then followed by a period of remodelling in order to beautify the structure.
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Angela Singer (born 1966 in Essex) is an artist of British and New Zealand nationality who lives in Wellington, New Zealand. An animal rights activist, she addresses the way in which people exploit animals and the environment through the repurposing and remodelling of vintage taxidermy, a process she calls "de-taxidermy". Since the 1990s her work has been exhibited both in New Zealand and internationally.
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Training and sleeping facilities were added through the early 1970s. The Boy Scout Association was renamed The Scout Association in 1967. During the 1970s, two key and popular facilities were built: the Dorothy Hughes Pack Holiday Centre for Cub Scouts and the Colquhoun International Centre for training Scouters, originally called The International Hall of Friendship. In the 1980s extensive remodelling of the White House was done.
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Since then continuous two-way working has been possible, using only Kombinationsignale (combination signals). During the remodelling of Muldenstein station, moveable point frogs were inserted into the continuous track at the northern end of the station. In addition, all level crossings were eliminated and new bridges were built. These included the northern Mulde flood bridge near Muldenstein, the Mulde bridge and the Leine bridge.
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On the northeast the wall was moved forward during nineteenth-century remodelling, destroying an aesthetically significant alignment between wall projections and the break in the roof arcade, which had been present in Vanbrugh's design.Gomme, Jenner and Bryan, p. 111 Visitors to the house as it stood after the completion of Vanbrugh's design would have first encountered a huge entrance saloon, two stories high.Gomme, Jenner and Bryan, p.
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But, by 1362, the project had not been concluded:Mario Jorge Barroca (2000), p.205 Álvaro Gonçalves Pereira had taken a lot of pacience in the construction and evolution of the castle, until his death in 1375. The fortress suffered various modifications over the centuries. During the reigns of King John II and King Manuel, there were remodelling to adapt the structure to the new military requirements.
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Lazar Lazaryan, russified as Lazarev, acquired the land near the corner of present-day Krivokolenny and Armyansky lanes in 1758. Between 1758 and 1812 the main house was gradually expanded, notably by Ovakim Lazarev, son of Lazar and founder of the Institute. Armyansky Lane area was spared by the Fire of 1812. In 1814 Ovakim Lazarev commissioned remodelling of the facade in Empire style.
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St John's is the oldest church in the city centre of Leeds. It was begun in 1631 and was consecrated in 1634, at a time when few churches were being built. It was paid for by John Harrison, who was a wealthy wool merchant and local benefactor. The church was altered between 1830 and 1838; this included remodelling of the tower by John Clark.
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The present house is a remodelling of an older house known as Neuadd Pergwm.Lloyd, T., ‘The Lost Houses of Wales: A Survey of Country Houses in Wales Demolished Since c.1900 The house came into the ownership of the Williamses of Blaen Baglan in around 1560. It is said that Oliver Cromwell was related, and so the house was saved from pillage during the English Civil War.
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After the damage Stella Solaris suffered in 2001, she was planned for yet another remodelling and further cruise service. However, in the years following, modern cruise ships began to overtake older ships in popularity. Maintenance costs rose and Stella Solaris was taken out of service in 2002. Along with hundreds of other relatively old ocean liners, she was sold for scrap around late 2003.
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John Newman considers the oldest part of the house to be the rear cross-wing. Cadw suggests that the five-bay frontage was added in the mid-18th century, intended to unify the appearance of the house. Newman calls it a, "typical 18th century manoeuvre". The interior was significantly remodelled at the same time, and Cadw considers that the extensive cellars were constructed during this remodelling.
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H3K4me3 is commonly associated with the activation of transcription of nearby genes. H3K4 trimethylation regulates gene expression through chromatin remodeling by the NURF complex. This makes the DNA in the chromatin more accessible for transcription factors, allowing the genes to be transcribed and expressed in the cell. More specifically, H3K4me3 is found to positively regulate transcription by bringing histone acetylases and nucleosome remodelling enzymes (NURF).
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In 2009/2010 Beefeater implemented a remodelling and retraining programme similar to the Brewers Fayre programme. All sites received a partial refurbishment, which featured a new colour scheme, carpets and furniture. In late 2009, the brand became known as Beefeater Grill. In September 2013, Beefeater began a partnership with the Gourmet Society, offering their members discounts on production of a Gourmet Society restaurant discount card.
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He was twice chairman of the foundation of Memorials and Museums Working Group of the International Holocaust Remembrance Alliance (IHRA). Goethe-Institute Washington DC, 2007\. Photo: Goethe-Institute As participant of the International Forum Mauthausen he is advising the Austrian Federal Ministry of the Interior on the remodelling of the Mauthausen-Gusen concentration camp memorial. He is also in the board of trustees of the ARSP.
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George Combe began the remodelling of the course in 1900, and was Convenor of the Green from 1900 to 1913. He was made an honorary life member in 1909 and continued making improvements to the course. Harry Vardon modified the course in 1908, the same year King Edward VII bestowed royal patronage on the club. In 1926, the Club brought Harry Colt in to make further improvements.
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Further remodelling in the 1990s and 2000s has seen the ticket office moved twice, accompanied by the opening, closing and re-opening of retail areas. A small, general corner store was also opened. The building is located at one side of the road bridge (now Railway Street) over the track, with a taxi rank located between the road and the building. Stairs lead down to the platforms.
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The frontage of the house carries a date of 1742 but this indicates the date of the house's remodelling. Its origins are earlier, dating from the late 17th century. A door lintel in the kitchen is dated 1684. The mid-18th century alterations gave the house a "Renaissance" façade, with a forecourt and a decorative gate and railings of ironwork, which are included in the house's listing.
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In Madrid, Antonio Lamela concluded two reference works. The first was the remodelling and extension in 1988 of the Santiago Bernabéu Stadium (Lamela holds membership number 59 for Real Madrid Football Club).Antonio Lamela. Detail of the extension of the Santiago Bernabéu Stadium The second is the award-winning Terminal 4 of the Barajas Airport (since 2014, the Adolfo Suárez Madrid-Barajas Airport), along with Richard Rogers.
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On March 15, 1922 approval was given for further alterations to the building. The name of the architect of these modifications cannot be ascertained. It is possible, however, that the work included a remodelling of the second floor accommodation spaces. In 1931 Tooth and Co. Ltd who were leasing the hotel, reported considerable losses in trade due to the high rent payable to the Sydney Harbour Trust.
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The MSB authorised the alterations and granted Tooth and Co. Ltd a twenty-year lease of the premises from the date of completion of the remodelling. In August 1938 bulk and bottled beer refrigeration equipment was installed. Later in 1947, the refrigeration system was to be replaced, and again in 1956. In 1941 part of the cellar was partitioned off to form a spirit room.
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An osteoclast () is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodelling of bones of the vertebral skeleton. The osteoclast disassembles and digests the composite of hydrated protein and mineral at a molecular level by secreting acid and a collagenase, a process known as bone resorption. This process also helps regulate the level of blood calcium.
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The family had the original Gothic castle rebuilt and the basic Renaissance remodelling carried out between 1542-1555, and the château acquired the name Nová Lhota.Tomaš Ehrenberger, The 88 Most Beautiful Castles, pg. 33-34, Kartografie Praha a.s., In 1597, the château was sold to Vilém Růt of Dírná who had the building rendered with red plaster, from which it got its name Červená Lhota.
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Julie Mundy is a British writer who focuses on 20th century history and pop culture, most notably Elvis Presley. She also runs Elvis Presley fansite Elvis fan club website, elvis.co.uk, "one of the main Elvis websites" in the UK, and acts as a judge at Elvis tribute act competitions. She also appeared on home improvement show 60 Minute Makeover getting an Elvis-themed remodelling.
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The rest of the building has been rebuilt and remodelled over the centuries. In the 18th century Sanderson Miller enlarged the nave and added two transepts. A further remodelling campaign, which transformed the building into its current form, took place in the 19th century. Pittern Hill Windmill In 2008, three new bells were cast to augment the bells to eight, one replacing an existing bell.
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Both ballcourts appear to have been remodelled after the Kaqchikel fashion, with thick coatings of stucco.Fox 1987, 2008, pp.187, 190–191. Around the 13th century, Group A underwent a major remodelling, including the construction of a new retaining wall and the infilling of the wide area between the old and new walls, creating a much expanded terrace for the construction of the group's architecture.
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Kirby started his career when he left school at the age of 16, initially on a YTS scheme at Leicestershire County Cricket Club having been discovered in his native Lancashire. While at Leicestershire he had to overcome sacroiliac instability, a chronic bad back, remodelling his action to learn to bowl fast again, but the county released him after five seasons without making an appearance.
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Also on the first floor are a kitchen pantry, a refrigeration area, and the servants' dining room. A bathroom was added below the central stair in the course of the 1923 remodelling. The second floor is taken up with four bedrooms, a sleeping porch, and two bathrooms. Servants' quarters, consisting of a single large room with several closets, occupied the whole of the attic.
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This initial "woven" bone does not have the strong mechanical properties of mature bone. By a process of remodelling, the woven bone is replaced by mature "lamellar" bone. The whole process may take up to 18 months, but in adults, the strength of the healing bone is usually 80% of normal by 3 months after the injury. Several factors may help or hinder the bone healing process.
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Christ Church Cathedral, New Zealand, constructed in the 1880s. The Cathedral of Tampico, Tamaulipas, completed in the late 19th century with additional remodelling. A tile floor at Hereford Cathedral in England is laid out in a swastika like pattern with arms pointed to the right. The floor at Amiens Cathedral in France features a right-facing swastika pattern with shortened arms, similar to the St. Cloud tiles.
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Southwestern portal of tunnel no. 1, the twin tunnels, of which only one is in use The tunnel scheme was briefly resuscitated in 1965 but was deferred once again in 1966. Work was eventually resumed in 1974 and included the remodelling of the lower section of the deviation between De Doorns and Osplaas stations as well as the construction of tunnel no. 1, the twin tunnels.
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Work was eventually resumed in 1974 and included the remodelling of the lower section of the deviation between De Doorns and Osplaas as well as the construction of the short twin tunnels. This was completed in 1976, at which point financial constraints resulted in yet another postponement. Authority to proceed was only given once again in late 1979.South African Construction World, July 1990, pp.
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After he became chancellor, Hitler drew up plans for expansion and remodelling of the main house and put Bormann in charge of construction. Bormann commissioned the construction of barracks for the SS guards, roads and footpaths, garages for motor vehicles, a guesthouse, accommodation for staff, and other amenities. Retaining title in his own name, Bormann bought up adjacent farms until the entire complex covered .
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In late 2015, the government of Basel-Landschaft canton approved a plan to convert the line from 750 mm gauge to meter gauge in 2023.. This will involve new passing loops and extensive reconstruction at Liestal and Waldenburg. The first step was the remodelling of Talhaus station (finished in 2018). Fully automatic operation is also being contemplated. Waldenburgerbahn AG merged into Baselland Transport in 2016.
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The Tivoli Theatre was a major performing arts venue in Melbourne's East End Theatre District, located at 249 Bourke Street. The theatre's origins dated from 1866, with various remodelling and rebuilding throughout its history. Its final building opened as the New Opera House in 1901, and was renamed the Tivoli in 1914 when it joined the Tivoli circuit. The Tivoli eventually closed in 1966.
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A projecting teacher's room was added to both the southerly and northerly verandah but otherwise it remained unaltered. The fence dividing the school was removed. Although the remodelling thoroughly updated the school buildings it did not increase the accommodation significantly. In 1928 a large timber Dux Board was installed in the school, recording the names of the boys, girls, and junior dux of the high school.
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Remodelling of the mall's façade and interior was performed in 2011 through 2012. In June 2013, Kitsap Mall and its surrounding properties (NorthPoint, Kitsap Place) were bought by Starwood Capital Group from Macerich. Dick's Sporting Goods was added in 2016. On August 31, 2019, it was announced that Sears would be closing this location a part of a plan to close 85 stores nationwide.
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On his return to England, he also acted as an interior designer, medal designer, and architect, creating the first tripod in metal since antiquity, building and remodelling country houses, garden buildings, and town houses (e.g. Shugborough Hall, Hagley Hall, Spencer House, and the Temple of the Winds), creating book illustrations, designing commemorative medals and tomb monuments, and being appointed Surveyor to the Royal Naval Hospital, Greenwich.
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In 2015 it was closed to visitors for major restoration works. During the 17th century various improvements were made to the court. One of the first acts of Charles II after his restoration in 1660 was to order the extensive refitting of the Tudor tennis court. This included the laying of a new tile floor, the remodelling of the galleries and repairs to the roof.
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There are several other places called Twyford. Twyford Hall is a Grade II listed 17th-century country house, situated on the A1067 to the north of the hamlet. St Nicholas's Church dates from Saxon times with a tower and porch from 1732 and later remodelling. The church is run as part of the heart of Norfolk group of rural parishes, with clergy based in North Elmham.
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After the season had finished, Gardner redesigned some sections of the car, altering the airbox, remodelling the nose section, lengthening the wheelbase and slightly narrowing the monocoque. The redesigned car became known as the 002 and 003, which were chassis numbers given to each of the cars made for the season. The team also switched tyre supplier to Goodyear after Dunlop withdrew from F1.
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Structural changes in T-tubules can lead to the L-type calcium channels moving away from the ryanodine receptors. This can increase the time taken for calcium levels within the cell to rise leading to weaker contractions and arrhythmias. However, disordered T-tubule structure may not be permanent, as some suggest that T-tubule remodelling might be reversed through the use of interval training.
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Anthropologists are also able to see other markers present on the bones. Past fractures will be evident by the presence of bone remodeling but only for a certain amount of time. After around seven years, bone remodelling should make the presence of a fracture impossible to see. The examination of any fractures on the bones can potentially help determine the type of trauma they may have experienced.
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On Sir Charles' death in 1906 the estate passed to his son Edward (1859–1920), who was created Baron Glenconner in 1911. Following a fire at The Glen in 1905, Robert Lorimer was commissioned to oversee repairs and remodelling of the interior. Formal gardens were also added at this time, to Lorimer's design. Further interior decoration was carried out by family friend Syrie Maugham in the 1920s.
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The modern wooden bridge over the neck ditch in front of the main castle was built as part of the remodelling in the 16th century. You enter the courtyard of the inner ward by the remains of the gateway. In the north are the ruins of the main building with three cellar rooms on the ground floor. The wooden fixtures and galleries are modern additions.
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Katapult roller coaster was also introduced that year. In 1998 a major remodelling of the park was carried out at a cost of 8,000 million pesetas (48 million euros). The work included dividing the park into 5 zones and adapting the appearance and name of each attraction to match their respective zone. The park was also decorated, more souvenir shops added and the number of shows increased.
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Craftsmen use them to mark clapboard and brick courses so that, for example, a course ends neatly below a window sill or at a door's architrave. They are used in remodelling so that, for example, the new coursing of exterior siding on a wing will match the existing. There is evidence of 'boning-rods' being used in building Egypt's Great Pyramid as counterparts of modern storey poles.
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This work included internal partitioning, boarding up of the skylight, installation of a suspended ceiling, re- concreting the floor, and the remodelling of the front awning. In 1977 the property was transferred to the present owners, who operate a real estate office. Alterations were carried out to enable the letting of various parts of the building. Existing tenants include a coffee shop and a hairdresser.
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The total number of theatres Matcham designed is unknown and has been the subject of much speculation. The architect Victor Glasstone estimated the architect's work to include 66 new theatres and the remodelling and restoration of 58 others, between 1879 and 1910;"King Kong versus Godzilla: The Competition for the Royal Opera House at The Hague, 1910–11" by Iain Mackintosh; Wilmore, p. 143.
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Therefore, this is not a valuable factor for early diagnosis of peri- implant mucositis. Alveolar bone loss following implant placement after first year in function should not exceed 2mm as generally between 0.5 – 2 mm of crestal bone height is lost during remodelling/healing process. As such changes ≥ 2mm during or after the first year should be considered as pathologic. Ie Peri-implant disease-induced.
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The Burrough's Building is situated at the front of the college, parallel to the Chapel. It is named after its architect, Sir James Burrough, the Master of Caius, and was built in 1736. It is one of several Cambridge neo-Palladian buildings designed by Burrough. Others include the remodelling of the Hall and Old Court at Trinity Hall and the chapel at Clare College.
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71 A sign commemorates acrimony around its restoration or remodelling, stating "Building restored November 2003. Despite the best efforts of The National Trust and Mrs Patrica Woods.". Patrica Woods was as the time president of the National Trust of Australia (Tasmania). The main street has a surveyor's cottage that was built around 1840 The Chudleigh show, run by the Agricultural and Horticultural society, is held each February.
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Nevertheless, the freight services operated never included the city of Santa Fe so the station continued with no use and entering into a deterioration process. Upper facade of Santa Fe building in 2013. Halls after remodelling. In 2008, the Cencosud consortium featured a project to build a shopping mall in the former station, with a cost of A$ 100 million and the creation of 1,200 job positions.
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The future of non-surgical care for partial patella tendon ruptures is likely bioengineering. Ligament reconstruction is possible using mesenchymal stem cells and a silk scaffold. These same stem cells have been shown to be capable of seeding repair of damaged animal tendons. In 2010, a clinical study proved that mechanical loading of the tendon callus during the remodelling phase leads to healing by regeneration.
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West Island Line Environmental Impact Assessment. Final Environmental Impact Assessment Report. Appendix 6.1: "Reclamation History", May 2008Kwok, Ka-chun, Peter, "Remodelling U.C. Complex in Kennedy Town", University of Hong Kong, 1995 In 1903, the Hong Kong Government erected seven boundary stones for the city, inscribed "City Boundary 1903". One of them is located at the Kennedy Town Temporary Recreation Ground at Sai Ning Street ().
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LeJeune's Bakery is a historic bakery located at 1510 Main Street in Jeanerette, Louisiana. Opened in 1884 by Oscar J. LeJeune as the Old Reliable City Bakery, the building underwent a major remodelling in 1918, when O.A. LeJeune and Walter LeJeune, Sr. purchased the bakery from Oscar. The building was renamed LeJeune's some time between 1918 and 1934. with five photos and a map With .
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Cine Latino was one of the largest cinemas in Mexico City, located on the south side of Paseo de la Reforma, the city's signature boulevard, at #296, in the Zona Rosa district of the Colonia Juárez neighborhood. It opened in 1960. It had two floors and a capacity of 1,850 spectators originally, and after remodelling could hold 2,500. It often hosted premieres such as "Lola la Trailera".
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The building will be extended to accommodate it. On 31 January 2007, the city council voted to accept this plan, with Greens, Citizens' Coalition, CDU and SPD members voting for it. The cost of the necessary remodelling and renovations is expected to exceed €19 million. An architectural contest concluded in October 2008; the entry of the Alexander Koblitz architecture firm of Berlin was chosen.
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The National Centre for Cell Science is a National Level, Biotechnology, Tissue Engineering and Tissue Banking research center located at Savitribai Phule Pune University campus in Pune, city of western indian state of Maharashtra. The institute formerly known as "National Facility for Animal Tissue and Cell Culture", is one of the premier research centers in India, which works on cell-culture, cell-repository, immunology, chromatin- remodelling.
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These join to form small vesicles called angiocysts which join up to form long vessels called angioblastic cords. These cords develop into a pervasive network of plexuses in the formation of the vascular network. This network grows by the additional budding and sprouting of new vessels in the process of angiogenesis. Following vasculogenesis and the development of an early vasculature, a stage of vascular remodelling takes place.
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This was changed by Hastings' remodelling of the façade. The house as a whole now has four bays with rusticated quoins on both corners. On the ground floor, from the east there are two round-headed windows, then the entrance door with a round arch, and then another round-headed window. The keystone of each of these arches bears the image of a Native American.
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The new castle was completed in 1823 in the Tudor style. Robert Fairfax owned the castle for 46 years until 1793 when it passed to the Wykeham Martins. Sale of the family estates in Virginia released a large sum of money that allowed extensive repair and the remodelling of the castle in a Tudor style, completed in 1823, that resulted in the appearance today.
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The one that stands now was built in the late 15th century; in 1895 it was remodelled and enlarged. Like all the municipality’s foregoing churches, it is consecrated to Saint Lawrence. The lovely Baroque altar from 1630 was sold to Schloss Gondorf at the time of the remodelling, but in 1968 it was bought back for DM 30,000. Beginning in 1794, Bremm lay under French rule.
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The hospital introduced a children's ward in 1929, by remodelling the male ward in the main block. It also built a new kitchen behind the tower block above the nurses' bedrooms. Additions to the 1921 "Record Plan" by the Government Architect's Office record the arrangement of buildings 1933. Where the ground sloped away to the east, a wing was added to the central block at basement and ground floor level.
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Attractions include the Sandy Lane Aqua Park with ferry to Meadows, Caldy Nature Reserve and Boughton Hall Cricket Club. Great Boughton came into the news when a controversial development at the disused Saighton Camp caused the remodelling of a roundabout. The new design features a hamburger roundabout which has also proved controversial and the roundabout now creates delays especially on the A41 where tailbacks frequently reach 2 miles.
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Miniature of the Supreme Parish Church in Berlin, as built by J. Boumann the Elder in 1750. Schinkel's remodelling, around 1830 On 6 September 1750, the new baroque Calvinist Supreme Parish Church was inaugurated, built by Johann Boumann the Elder in 1747–1750. The electoral tombs were transferred to the new building. The new structure covered a space north of the palace, which is still covered by the present building.
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After the marriage of Pedro I and Archduchess Maria Leopoldina of Austria in 1817, the Imperial couple resided in the palace. The future Queen of Portugal, Maria II, and the future Emperor of Brazil Pedro II were born here. Empress Maria Leopoldina died in the palace in 1826. Pedro II, future Emperor, grew up and was educated in the palace, and in 1869 ordered the remodelling of the gardens.
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In addition to tours, the museum hosts art classes and concerts. Malcolm Munthe spent much of his life after the second world war remodelling the family's two mansions in England. His children formed the Pennington-Mellor-Munthe Charity Trust which maintains both Southside and Hellens Manor and operates them as museums, also hosting cultural events such as concerts, lectures and literary events. Members of the family still sometimes reside at them.
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The church has a narrow façade ingeniously modelled into three bays on two levels with the centre bays projecting slightly. The composition gives the impression that the façade is larger than it actually is. In the remodelling of the church Carapecchia accentuated the vertical dimension of the façade by having superimposed pilasters of equal heights. The upper columns and pilasters are slightly more slender than the lower ones.
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By the 1930s, the main school building was badly in need of repair. In 1932-1933, Works Department prepared a remodelling scheme to cost approximately . This comprised partitioning each floor into seven classrooms and teachers' rooms; walls were remodelled to permit maximum light and ventilation; and two sets of concrete stairs were constructed from the first floor, at the rear of the building. The building was rendered at this time.
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Huggins supplied stone quarried from his own land at Hadlow Grange. Fellowes Prynne studied architecture in Canada and later worked with George Edmund Street. He was responsible for St Wilfrid's Church at Bognor Regis and the fittings (especially reredoses) of many other churches in Sussex. There is uncertainty over how extensive his work at St Mark's Church was, and whether it can be considered a mere remodelling or a complete reconstruction.
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The show began on BBC Two, at 9pm on 4 September 1996, before transferring to BBC One for the start of the third series in 1998. The final edition was broadcast on 22 November 2004 after a successful 8 year, 17 series run. The cancellation was announced on 27 August 2004. Changing Rooms was originally hosted by Carol Smillie, and assisting with the remodelling was a Cockney carpenter, "Handy" Andy Kane.
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He attended the Vienna University of Technology and earned a doctorate in architecture in 1919. His daughter Judith Holzmeister was born in Innsbruck in 1920. After submitting a prize-winning design, he became the Head of the Architecture Department of Austria's Academy of Fine Arts in 1924. In 1926 he oversaw the remodelling of the Festival Theatre in Salzburg, then spent several years erecting government buildings in Ankara, Turkey.
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The first of the grand "original six" department stores was built in Calgary in 1913. The other department stores that followed were in Edmonton, Vancouver, Victoria, Saskatoon, and Winnipeg. The First World War interrupted a major remodelling and restoration of retail trade shops planned in 1912. Following the war, the company revitalized its fur- trade and real-estate activities, and diversified its operations by venturing into the oil business.
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Electrification on the railway system in the eastern region required major repair and overhaul facilities for Electric Locos, EMU Rolling Stocks since the early 60's. Kanchrapara was selected to play the key role in all these spheres. In 1962 a decision was taken for remodelling Kanchrapara Workshop in order to make it a base workshop for electric locos, EMU rolling stocks of Eastern and South Eastern Railways.
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Outside, the aisles were covered with a terrace punt, the roof being reserved for the nave: thus there was the effect of a basilica on two levels. This silhouette disappeared with the Gothic remodelling. A deambulatory with radiating chapels developed around the church which preserved a part of its murals. A crypt of the 11th century, dug a posteriori under the choir, also preserves frescos of the time.
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During periods when they have lost their digestive tracts, sea cucumbers live off stored nutrients and absorb dissolved organic matter directly from the water. The regeneration of lost parts involves both epimorphosis and morphallaxis. In epimorphosis stem cells—either from a reserve pool or those produced by dedifferentiation—form a blastema and generate new tissues. Morphallactic regeneration involves the movement and remodelling of existing tissues to replace lost parts.
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Its interior retains elaborate decorations, including plaster cornices and marble chimneypieces, dating from Robertson's remodelling. In the grounds is an 18th-century garden house, octagonal in shape with a pyramid roof, which contains a sundial dated to 1661. The grounds are accessed by two gates, which have square ashlar gatepiers with carved ball finials, which are included in the listing for the building. The house has been praised for its elegance.
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Bohun swan supporters with arms of George Fownes Luttrell (1826–1910) impaling Hood, 19th century remodelling of main entrance door to Dunster Castle The Luttrell family, feudal barons of Dunster, of Dunster Castle in Somerset, also used the Bohun swan as supporters. This was due to their descent from the Courtenays. Sir Andrew Luttrell (d.1378/81) of Chilton, in the parish of Thorverton, Devon, married Elizabeth Courtenay (d.
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The deeper layers, if reshaped by a laser or cut by a microtome, will remain that way permanently with only limited healing or remodelling. With PRK, the corneal epithelium is removed and discarded, allowing the cells to regenerate after the surgery. The procedure is distinct from LASIK (laser-assisted in-situ keratomileusis), a form of laser eye surgery where a permanent flap is created in the deeper layers of the cornea.
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Further alterations were made to the church in 1885–6 by Matthew Ellison Hadfield and George Webster. The confessionals were removed providing space for two new chapels, and the remodelling of the chancel. The altar was raised and a new super altar made from Hopton Wood stone placed on it. New confessionals were built outside the walls and a third chapel, of the Sacred Heart, was added at the north end.
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Chacarita estrenó su nuevo estadio The new stadium was erected in the same location where the old one was, in the Villa Maipú neighborhood, General San Martín Partido. The last game played by Chacarita before the remodelling had been on 21 October 2005, during a match for the Primera B Nacional championship. The rival was Tigre (which has a strong rivalry with Chacarita) and El Funebrero won 3–0.
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A base batter is present, and can be attributed to the earlier structure. The conversion to a castle/towerhouse has resulted in a rectangular shape to the castle which is 11×15 metres. By 1299, the Cantwell family were tenants, with Thomas Cantwell paying taxes on the castle. The building then fell into Gaelic hands, and the Ormond O’Kennedys were responsible for the remodelling of the building into a tower house.
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Prolonged usage of loop diuretics will also contributes to resistance through "braking phenomenon". This is the body physiological response to reduced extracellular fluid volume, where renin- angiotensin-aldosterone system will be activated which results in nephron remodelling. Nephron remodeling increases the number of distal convoluted cells, principle cells, and intercalated cells. These cells have sodium- chloride symporter at distal convoluted tubule, epithelial sodium channels, and chloride-bicarbonate exchanger pendrin.
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There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing.
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The palace fell out of use in the Stuart period in favour of nearby Theobalds. In 1608 James I had it partly demolished and the materials used for extensions there. The remaining part, including the gatehouse and hall, was occupied from 1616 to 1623 by Philip Herbert, Earl of Montgomery. By 1630 however he had succeeded his brother as Earl of Pembroke and was busy remodelling Wilton House.
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A range of government departments occupied The Mansions until the 1970s. The Government Statistician's Office was located on the ground floor from and by 1961 the Medical boards, Licensing Commission, Prices Branch, Department of Public Works and Probation Office occupied the first floor. Replanning of the Medical boards' offices took place in 1967 and remodelling of the ground floor for the Comptroller-General of Prisons occurred in 1972.
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A Conservative, he was opposed to the re-imposition of a duty on foreign corn, and generally all duties on "the necessaries of life". He opposed the Maynooth Grant and taxes upon income, but not on property. He was in favour of remodelling the Boards of Custom and Excise, extensive Chancery reform and a moderate Parliamentary reform. In later years Horsfall owned and resided at Bellamour Hall, Colton, Staffordshire.
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The Roman baths incorporated a reused inscription of the Gallic Emperor Postumus, dating from AD 262–266. The 3rd-century fort was garrisoned by the ala Sebosiana and the numerus Barcariorum Tigrisiensium.Birley, CW- XXXIX, p. 222. The ancient Wery Wall was identified in 1950 as the north wall of the 4th-century fort, which constituted a drastic remodelling of the 3rd-century one, while retaining the same orientation.
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Its famous garden is walled about, like a medieval garden, overlooked by the upper-storey loggias, with which Michelozzo cautiously opened up the villa's structure. Michelozzo's Villa Medici in Fiesole has a more outward-looking, Renaissance character. The property was purchased in 1417 by Cosimo de' Medici brother, Lorenzo. At the death of Giovanni di Bicci, Cosimo il Vecchio set about remodelling the beloved villa around its loggia-enclosed central courtyard.
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Ethan and Casey were childhood sweethearts. They first met at a school dance in 7th Grade in Denton, Texas, and married at the age of 23 at Grace Temple Baptist Church in Denton, on June 19, 1999. Ethan owns the remodelling company Eliot J Construction and attended Executive MBA program by Baylor University, graduating in May 2010. Since 2005, the couple has lived in the Steiner Ranch community of Texas.
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West Croydon (2008 image) with Southern branding The main entrance is on London Road, a short distance from the main shopping area. There are ticket barriers protecting the platforms. Trains run to London Victoria, , , and Sutton and from there to west Surrey and West Sussex. By December 2009 station remodelling and tracklaying were completed for the southern extension of the East London Line, of which West Croydon is a terminus.
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Dossier, pp. 19-20 and 22, with pictures. Remodelling in the 1770s involved the destruction of some medieval parts, but greater destruction followed the French Revolution. The monastery was suppressed in 1791, and on May 4, five days after the monks departed, the buildings and land were bought by Emmanuel Crétet (1747–1808), later to be Minister of the Interior under Napoleon with the title Comte de Champmol.
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The west side wing comprises a lobby area, and the offices of the court of petty sessions and the police magistrate. Behind the court room, the Judges chamber and the office of the Attorney General are located. No room is larger than the central courtroom. The 1973 remodelling of the court room space created a clerk of the court public office that occupies the front section of the building.
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The nave was extended westwards with the bell tower at the west end of the church left standing on four oak posts so that the bells are now rung from the centre of the aisle. During the enlargement and remodelling of the chancel, the remains of twenty burials were found, as was a brass plate engraved with the date 1440 which still had a bunch of lavender placed underneath it.
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Congestion relief at King's Cross Being addressed by the major redevelopment already envisaged. Congestion relief at Finsbury Park This station suffers from severe congestion at peak times, and services are set to expand. Various options were to be examined, but would probably include re-instating of a disused platform (see Option A below). Congestion relief at Peterborough To be taken forward in conjunction with partial remodelling (see Option C below).
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In September 1688, his nephew Lord Norreys treated some of the country gentlemen of Oxfordshire to solicit support for Henry in the anticipated elections. He was reinstated at Oxford in October when the King began to reverse the program of remodelling the corporations. By this time, the Glorious Revolution was already in train. Early in November, Abingdon was the first of the peers to openly take arms for William of Orange.
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Angiogenesis, the formation of new blood vessels, is often critical for tumour cells to survive and grow in nutrient-depleted conditions. Akt is activated downstream of vascular endothelial growth factor (VEGF) in endothelial cells in the lining of blood vessels, promoting survival and growth. Akt also contributes to angiogenesis by activating endothelial nitric oxide synthase (eNOS), which increases production of nitric oxide (NO). This stimulates vasodilation and vascular remodelling.
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These features, again greatly rebuilt, still survive today. The castle was reconstructed by Sir William Brabazon in 1547. The external walls and towers came under heavy fire during the Sieges of Athlone in 1690-91 and were later destroyed when lightning struck the castle in 1697. The castle as we view it today shows signs of extensive remodelling during the Napoleonic era when it was modernised and adapted for artillery.
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In preparation for building the Northwest Runway, the substation was being moved and modernized with gas insulated switchgear, power lines undergrounded or removed. Kelsterbach has at its disposal a combination indoor and leisure swimming pool. Remodelling and modernization are planned for 2007. Furthermore, also at hand are one of Groß- Gerau district's biggest and most modern town libraries, an integrated comprehensive school, several primary schools, and a special school.
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He ordered Alexander MacDonnell, Earl of Antrim, a Catholic nobleman of Scottish origin, to raise the Ulster regiment. Antrim, already in his seventies, hired 1,200 Scottish mercenaries (called redshanks), making sure they were all Catholics. The unit was supposed to be ready on 20 November, but delays occurred. At that time Tyrconnell's remodelling of the Irish army had advanced so far that few units still had significant numbers of Protestant soldiers.
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The ornate coat-of-arms of the Canto e Castro family, still retained on the structures. The building experienced several remodelling projects and extensive alterations associated with the 1980 Azores earthquake, which resulted in major damage, in particular to the chapel annex. Over the main doorway of the manorhouse are the coat-of- arms for the Canto e Castro family, the principal descendants and property- owners until the late 20th century.
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A first castle was built on the ruins of an earlier Gallo-Roman structure. The present Château de la Muyre was constructed from limestone by an unknown architect at the start of the 15th century.Ministry of Culture Inventaire général du patrimoine culturel: Domblans Over the years, there have been important additional works and remodelling, in particular in the 19th century. Recycled stones bear the dates 1581 and 1616.
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Disturbed flow patterns can promote the formation of valves and increasing pressure can affect the radial growth of vessels. The primitive heart within the first few days of contraction is best described as a peristaltic pump, however after three days the flow becomes pulsatile. Pulsatile flow plays an important role in vascular remodelling, as flow patterns can affect the mechanotransduction of stress to endothelial cells.Buschmann, I. et al.
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Sources differ as to whether this was a new building, or remodelling of an earlier Brunel building. In 1898 the single sided station layout was replaced by a conventional design with 'up', 'down' and 'relief' platforms linked by a pedestrian subway. Access to the station from Broad Street was not direct, until Queen Victoria Street was built in 1903. This provided a route through to Friar Street and Station Road.
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Architect Anna Meszaros from firm Cameron Chisholm and Nicol was responsible for this refurbishment. Most recently, the building was refurbished from 2001 to 2002, which also involved remodelling of the three-storey building adjacent to the tower. This involved an upgrade of some floors, the lobby and the adjoining ANZ Bank branch. The outdoor plaza was also to be revamped for the first time since the building was opened in 1976.
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Under the new Crown ownership, the building was originally intended as a private retreat for King George III's wife, Queen Charlotte, and was accordingly known as The Queen's House. Remodelling of the structure began in 1762.Harris, p. 24. In 1775, an Act of Parliament settled the property on Queen Charlotte, in exchange for her rights to Somerset House, and 14 of her 15 children were born there.
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John Elliott had four children, two from his first marriage to Lisbet Frolich, Timo and Maja, and two children from his marriage to Erika Grohmann, Kelsey and Yolande. John and Erika raised Kelsey and Yolande in Hong Kong before moving back to the UK, where they lived in Sandbanks, Dorset. Two years later they moved to their 1930s Art Deco home in London, which John spent several years remodelling.
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In 1608 it was sold to Thomas Stephens whose son demolished the southern gatehouse and some of the outbuildings. He also installed a new staircase and continued the remodelling of the interior. Robert Packer of Donnington Castle bought Little Sodbury Manor in 1728, following further storm damage in 1703 after which the house was remodelled. It then passed down through absentee landlords and by the 19th century had fallen into disrepair.
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The Church of St Mary Magdalene in Great Elm, Somerset, England, dates from the 12th century and is a Grade I listed building. In the 13th century the two-bay nave was lengthened, possibly when the tower was added around 1240. The chancel was widened around the same period. Some of the Romanesque fabric of the original Norman building can be seen despite the remodelling in the early 17th century.
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These consist of angels bearing torches above a pendant showing the Pelican in her piety. During the remodelling of the east end in 1939, a new lamp was supplied by Charles Henshaw of Edinburgh. Over the years, the pendants went missing and one lamp was stolen; in 2006, Powderhall Bronze of Edinburgh manufactured replacements. The Bromsgrove Guild also produced the handles and keyhole escutcheon for the Chapel door.
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Marbury Hall c. 1819 The Marbury Hall of 1714 was a vernacular building in brick, which Lord Barrymore extended with side wings and a portico. In 1837, Thomas Moule described the hall before Salvin's remodelling as "a spacious building with a Doric corridor on the entrance front". The hall was enlarged and remodelled in around 1856 by architect Anthony Salvin, based on the great French château of Fontainebleau.
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Yu & Fellows et al. (2018) demonstrated that FOXO3a activation in vascular smooth muscle cells induces prominent apoptosis and extracellular matrix breakdown in vitro and exacerbates atherosclerosis and vascular remodelling in vivo. Also, these processes were at least partially dependent on MMP-13, as shown by siRNA knockdown and specific pharmacological inhibition. Further experiments also revealed MMP-13 as a novel, bona fide transcriptional target gene of FOXO3a in VSMCs.
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Wightlink planned to spend £17.5 million on improving its Portsmouth to Fishbourne route. This involved remodelling the terminal facilities at both Fishbourne and Portsmouth. The flagship was to have its upper car deck adjusted so vehicles access it directly from on-shore ramps. Two of the older ferries were to be stretched in length by 12 metres, with upper car decks similar to St Clare's being added, replacing movable mezzanine decks.
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The palace was built in 1530 by Philip of the Palatinate in the Renaissance style. From 1716 to 1724, it was transformed by Johann Franz Eckher into the Baroque style. In 1816, it was taken over by Napoleon's stepson, Eugène de Beauharnais, and his wife, Princess Augusta of Bavaria. According to the neoclassical plans of the court architect Leo von Klenze, the palace experienced further remodelling in 1836.
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By the 18th century, the Great Hall must have seemed old fashioned, and a surviving design of suggests that Cuthbert Constable intended to completely remodel the interior. However, it appears that remodelling was not undertaken until the 1760s when his son William Constable commissioned a number of architects for designs. These included John Carr, Timothy Lightoler and Capability Brown. The decorative plasterwork was executed by James Henderson of York.
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Isaac's father, William Carothers, was a Streets and Sanitation ward superintendent. William Carothers replaced his father-in-law, Isaac "Ike" Sims as committeeman in 1976. While alderman, William Carothers and his assistant Ozzie Hutchins threatened to block a $14.5 million Bethany Hospital expansion unless they received $15,000 worth of remodelling in their ward office. Both William Carothers and Hutchins were convicted of conspiracy and extortion on August 23, 1983.
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Integrin αvβ6 is found exclusively on epithelial cells. In most resting normal cells, little ITGB6 is produced, however the highest levels are found in the stomach, gall bladder and lung. ITGB6 levels increase in cells remodelling tissues so αvβ6 expression is increased in development, wound healing, but also in fibrosis and cancer. The principal function of αvβ6 is the activation of cytokine transforming growth factor-b1 (TGF-β1).
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It is renewed about every 16 years, most recently in May 1986, August 2003 and August 2019.Around the Regions Rail Enthusiast issue 59 August 1986 page 55July start for King’s Cross throat remodelling work The Railway Magazine issue 1419 June 2019 page 89 During the August 2019 renewal the wooden bearers were replaced with Fiber Form Urethane (FFU) which is expected to have a 30-40 year working life.
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There was a freestanding bell tower behind the church. In 1905 a three-story square belltower with a pyramidal roof surmounted by a decorative finial was added. In 1905-06 a two-story flat- roofed addition was added. A further addition of a one-story flat-roofed brick section for offices was added much later, probably during remodelling in the 1950s, which also covered the original brick building with stucco.
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Gerlach was born in Spandau. In 1707, he succeeded Martin Grünberg as royal director of building (königlicher Baudirektor und Leiter des Bauwesens) in Berlin. King Frederick William I of Prussia promoted him to Oberbaudirektor der königlichen Residenzen in 1720, making him responsible for all building of the state including bridges and fortifications. Gerlach directed the remodelling of the Kronprinzenpalais in 1733, and built the Kollegienhaus/Kammergericht in 1734/35.
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In the summer of 1859, Boucicault and William Stuart became joint lessees of Burton's New Theatre (originally Tripler's Theatre) on Broadway just below Amity Street. After extensive remodelling, he renamed his new showplace the Winter Garden Theatre. There on 5 December 1859, he premiered his new sensation, the anti-slavery potboiler The Octoroon, in which he also starred. This was the first play to treat seriously the Black American population.
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This places the chambers and major vessels into the correct alignment for the developed heart. Further development will include the septa and valves formation and remodelling of the heart chambers. By the end of the fifth week the septa are complete and the heart valves are completed by the ninth week. Before the fifth week, there is an opening in the fetal heart known as the foramen ovale.
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The house was set in 6 acres of grounds with three bedrooms, with an apple and pear tree orchard with two water wells. The house is symmetrical, white and surrounded by gardens, with a brick wall along the perimeter of the property to the road. The design of the house has been likened to an "18th-century doll's house". The house required extensive renovations and remodelling, and the installation of electricity.
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The Ice House was built in 1772 by ‘Capability’ Brown during the extensive remodelling. An Ice House was a ‘must have’ accessory of the day amongst leading gentry, with growing demand for refrigerated food, sorbets and ice creams. Ice was cut in blocks from the lake during the winter and dragged up to the Ice house. A drain at the bottom allowed water from the melted ice to escape.
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The grindstones were excavated so that the block of stone was in one piece and more or less already shaped underneath on the outside. Thus each of them left a round or oval hollow, or imprint, on the surface of rock it came from. These "negative imprints" are found all over the surface of the stone quarried, following the relief and remodelling it. Thus their disposition varies with said relief.
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The TNFRSF11A gene is present in chromosome locus 18q21.33, which encodes for the receptor activator of NF-κB (RANK). RANK is expressed in immature osteoclasts, which facilitates osteoclasts maturation upon binding of RANK ligand (RANKL). Binding of RANK ligand mediates the RANK/RANKL/OPG signalling pathway. The pathway mediates osteoclast differentiation and activation by promoting differentiation of precursors into multinucleated osteoclasts, and activating osteoclasts, thereby contributing to bone resorption and remodelling.
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The monarch first set about rebuilding Ujazdów Castle which he chose as his summer residence. Work was begun in the castle's forefield, where a series of straight paths converging at circles was laid out. The remodelling of the old Ujazdów Castle, which received an additional storey and new wings, dragged on without producing the expected results. The king became discouraged, abandoned further work and shifted his attention to the surrounding gardens.
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Downregulation of miR-590 by nicotine has been found to play a key part in the generation of atrial fibrosis by atrial structural remodelling. This downregulation sees the removal of post-transcriptional repression of TGF-β1 and TGF-β receptor type II (TGF-βRII), and consequent collagen production. miR-590 downregulation has further been shown to be mediated by activation of alpha-7 nicotinic acetylcholine receptors (α7-nAChRs).
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In 1988, the municipal council acquired the building of the Teatro Circo for 30,0000 contos. Around 2000,The first phase of the remodelling and requalification project, began with the restoration and safeguarding of elements considered more significant to the property, specifically the public areas, great hall, foyer, roof and two principal facades (with the maintenance of existing decorations. new remodelling under the supervision of Sérgio Borges (budgeted at around 2.6 million contos) with funds from European Union and Ministry of Culture (Rede Nacional de Teatros e Cine-Teatros and Rede Municipal de Espaços Culturais) partnerships: the rejuvenated Circo was re-inaugurated on 27 October 2006,with an expansion project, interior and exterior remodeling by Architect Sérgio Borges, serving the municipality of Braga. with profound changes in terms of interior compartmentation, colors and finishes, both interior and exterior, recreating elements and decorative friezes sought to resume the original work after consecutive years of alterations and adaptations, which made the original building uncharacteristic.
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Joaquim Possidónio Narciso da Silva, one of the many architects that were involved in the construction, remodelling and renovations at the Ajuda Palace over time Following the tragic deaths of members of the Royal Family in 1861 from typhoid fever, there were many who counselled King Luís to abandon the Palace of Necessidades. After being acclaimed King (22 December 1861), Luís moved temporarily with to the Palace of Paço de Arcos, while remodelling occurred at Ajuda to adapt the building to become the new Royal Residence. At the same time, a match was made between Luís and Maria Pia of Savoy, daughter of King Victor Emmanuel II of Italy, who were married in 1861; on 16 April 1862, the new King and his wife, moved into the Palace transforming it into the formal Royal Residence. In order to become liveable, the King directed Possidónio da Silva and Costa Sequeira to renovate and remodel the building, primarily based on the tastes of the Queen.
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Longrich admitted that the fact that Horner in his histological study could only find Triceratops subadults was suggestive, but offered the alternative explanation that Triceratops differed from its relatives in retaining a relative young bone structure until old age. On the other hand, bone remodelling is not a reliable estimator of maturity, in view of experimental studies demonstrating that differences in the mechanical strain conditions of various bones can significantly alter the rate or degree of such remodelling and may generate the illusion of old bone tissue. Longrich foresaw that Scanella and Horner would respond to his second test of their hypothesis by claiming that its results were caused by individual variation. According to Longrich, the importance of this factor was limited however: e.g. the size difference between ANSP 15192 and YPM 1831 had better been explained by sexual dimorphism, the former possibly being a young adult female, the latter a subadult male.
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They function as regulators of vesicular traffic and actin remodelling. The small ADP ribosylation factor (Arf) GTP-binding proteins are major regulators of vesicle biogenesis in intracellular traffic. They are the founding members of a growing family that includes Arl (Arf-like), Arp (Arf-related proteins) and the remotely related Sar (Secretion-associated and Ras-related) proteins. Arf proteins cycle between inactive GDP-bound and active GTP-bound forms that bind selectively to effectors.
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In 1958 the owners opened the state's first drive- through bottle shop with vehicular access from Stirling Highway. It was designed with a modern butterfly roof by Bill Evans, from Marshall Clifton's architectural practice. In 1986 Marie Wordsworth, the daughter of Bertie Johnston, commissioned architects, Overman & Ziudeveld, to undertake extensive remodelling of the building, which included landscaping works and the expansion of the ground floor space to make it larger and more viable for functions.
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The present house was built by the 3rd Earl of Bute to the designs of the neoclassical architect Robert Adam. Work commenced in 1767. The original plan had been for a grand and magnificent new house, but the plan was never fully executed and much of the work was a remodelling of the older house. Building work was interrupted by a fire in 1771 but by 1774 the house, though incomplete, was inhabited.
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House number 18 was the location of the prison prefect. The demolition of the shabby stalls by the cathedral occurred at this time. The Gothic palace which dated from 1293 was largely in disrepair by 1816 and a Stadthaus was built on its location by 1818, according to the plans of Nicolaus Blohm. In 1823 the building inspector Friedrich Moritz Stamm submitted a design for the complete remodelling of the square, which was accepted.
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In the mid 19th century, Hospitalfield House was expanded by Patrick Allan-Fraser, a patron of the arts. Allan-Fraser, the son of an Arbroath weaving merchant, studied art in Edinburgh and was once president of the British Academy of Art in Rome. In Arbroath, he completed a series of paintings for an edition of Scott's The Antiquary. After acquiring the Hospitalfield estate through marriage he embarked on a substantial remodelling programme.
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A remodelling in 1925 increased the capacity of the building to 1,250 from 800, increasing the length of the building by 40 feet. At the same time, classrooms were built at the sides, a choir loft added in the rear, and the organ loft rebuilt. Formerly a member of the Presbyterian Church in the United States, it seceded in 1983 and joined the Associate Reformed Presbyterian Church. The current pastor is Derek Thomas.
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Barrier activity has been linked to the disruption of specific processes in the heterochromatin formation pathway. These types of insulators modify the nucleosomal substrate in the reaction cycle that is central to heterochromatin formation. Modifications are achieved through various mechanisms including nucleosome removal, in which nucleosome-excluding elements disrupt heterochromatin from spreading and silencing (chromatin-mediated silencing). Modification can also be done through recruitment of histone acetyltransferase(s) and ATP-dependent nucleosome remodelling complexes.
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Blackadder North Lodge, undergoing restoration in 2007 The original peel tower was probably relatively unchanged until the mid eighteenth century. Around then James Playfair drew up plans for substantial rebuilding and remodelling of the earlier house, but these were not undertaken. Later, Robert Adam drew up plans which were carried out. In 1842 the house was described as an elegant modern edifice with extensive shrubberies and greenhouses and a beautiful Gothic conservatory.
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It is not known exactly when Ye Olde Man & Scythe was originally built, but a charter of 1251 permitting the market mentions it by name. It has been rebuilt at least once (1636 according to the datestone inside), and only the vaulted cellar remains of the original structure, though some internal beams remain from 1636. The frontage of the building is an early 20th-century remodelling. It is a Grade II listed building.
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In the 1950s, Bunshaft was hired by the State Department's Office of Foreign Building Operations as a collaborator on the design for several U.S. consulates in Germany. Bunshaft's only single- family residence was the 2300 square foot (210 m²) Travertine House, built for his own family. On his death he left the house to MoMA, which sold it to Martha Stewart in 1995. Her extensive remodelling stalled amid an acrimonious planning dispute with a neighbour.
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He became an adviser to King John II of Portugal and later Manuel I, being successively appointed Bishop of Tanger (1491–1500), Bishop of Ceuta (1500–1504) and Bishop of Viseu (1505–1519). During his rule, he led a comprehensive artistic remodelling of Viseu Cathedral. Ortiz advised the Portuguese kings on matters related to astronomy and navigation during the Age of Discovery. Manuel I named him tutor of his heir, future John III of Portugal.
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From September 2009, the school became an academy sponsored by the Ormiston Academies Trust. The school was then renamed Ormiston Sandwell Community Academy. Today, the school mostly serves pupils living in the Oldbury, Tipton and Rowley Regis areas of Sandwell. In 2013 the academy started a two-year build programme which saw over £10 million spent on a mixture of new build, remodelling and refurbishment as well as enhancing IT provision and student areas.
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As Heidermanns observes, this exclusion is based solely on the external circumstances of preservation and not on the internal features of the language. The end of the period is less controversial. The sound changes reflected in spelling during the 11th century lead to the remodelling of the entire system of noun and adjective declensions. There is also a hundred-year "dearth of continuous texts" after the death of Notker Labeo in 1022.
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The Wilgartaburg is one of the oldest castles in the Palatinate region, probably dating to the 8th or 9th century. According to an unverified source it was built in the late 10th or early 11th century by an abbot of Hornbach Abbey, initially as a wooden castle. In the Salian era (11th century) it was rebuilt in stone. This was expanded in the 12th century and a final remodelling took place in the 13th century.
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In 1540 he was associated with Thomas Cranmer, Lord Chancellor Rich, and other commissioners in the work of remodelling the foundation of Canterbury Cathedral, ousting the monks and supplying their place with secular clergy. He profited largely by the dissolution of the monasteries, obtaining many grants of land which had belonged to them in Kent.Dictionary of National Biography, Hales, Sir Christopher (d 1541), master of the rolls, by J. M. Rigg. Published 1890.
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After the Georgian remodelling of the castle, it was decided it would be more convenient to perform executions nearer the castle. The spot chosen became known as Hanging Corner. Lancaster has a reputation as the court that sentenced more people to death than any other in England. This is partly because until 1835 Lancaster Castle was the only Assize Court in the entire county and covered rapidly growing industrial centres including Manchester and Liverpool.
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In 1946 he restored the house for himself, remodelling the kitchen to the servantless times (though he continued to be looked after by housekeeper friends). His parents' bedroom was added to his office space. Murals by Peter Thompson and Stephan Knapp, and furniture to Gwynne's own design, were added over the years. He continually modified the house over time so that it represents design from the 1930s and 1950s to the 1970s.
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During this period he contributed greatly to civic improvements in the city, overseeing the redesign of North Bridge, and remodelling of Parliament Square. In 1865 he moved to new offices in Pitt Street (now renamed Dublin Street). In 1843 he, and his family, left the established Church of Scotland and joined the Free Church of Scotland. This led to his involvement in the new headquarters for the Free Church Offices on the Mound.
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From 1931 to 1937, the church was reconstructed to a design by architect Francisco Porrata Doria. The current facade bears a French neoclassical style. Among these improvements were the addition of two new chapels, a new roof, the remodelling of the upper storey of the facade and the construction of two new, richly decorated square towers. A pipe organ was installed in 1934 and re-inaugurated in 1989 after a nine- year restoration.
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After taking over as Brentford manager in January 1987, Steve Perryman continued the remodelling of his squad through the 1987 off-season.White, p. 334-336. Transferred out were defender Phil Bater, midfielder Paul Maddy and forward Francis Joseph, with the deals raising £37,000. In came a number of players on free transfers or a trial basis, the most notable of whom being former Chelsea midfielder Colin Lee, in a dual player/Youth Development Officer role.
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The large shaped gables feature theatrical masks of comedy and tragedy. Bryden also designed the nearby Old Clubhouse (originally the Union Club), Solomon's Temple and the remodelling of the Thermal Baths in the 1880s. When Buxton Cinema opened in 2017, it marked the end of three decades for the town without a cinema and a return to the original cinema venue in the town. Buxton's first cinema was The Hippodrome in 1903.
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This was because of high demand from away supporters, who had previously had to pay for a seating ticket, even though they preferred to stand. Even before this remodelling was complete, Malmö FF lowered the away ticket prices to match the price of a home terracing ticket. This restructuring was completed before the 2010 season. The terracing for the home supporters was also modified to ease mobility, and combat safety issues in the stands.
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In 1832, the schoolhouse got a belltower. Since classes in Nanzweiler were also attended by schoolchildren from neighbouring villages, the single classroom became too small, for a time even housing 100 pupils. In 1894, the municipality had the old schoolhouse torn down, and on the same spot arose a new one with more room and also a teacher's dwelling. The dwelling, however, was converted into another classroom in remodelling work done in 1936.
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In the 14th century a new inner ward was built along with Late Gothic fortifications. The Lords of Bítov became the new owners of the castle and based themselves here for four centuries. They carried out further improvements to the defensive capabilities of the castle. Bítov finally underwent Baroque remodelling, and gained its present form at the beginning of the 19th century, when it passed into the hands of the Counts of Daun.
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The house incorporates a three-storey tower of medieval origins. The central two-storey block of five bays dates from the early 18th century. Substantial additions were made in the Gothic Revival style in about 1862, but much of the 19th-century work has not survived a remodelling of the property in 1980. Structures of the North East In 2005 the east wing was occupied by the Turnbulls and in 2010 by the Rogers family.
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"Illinois Historic Sites Survey Inventory: Courthouse". Springfield: Illinois Historic Preservation Agency, n.d. With the state planning to convert the courthouse into a museum, Fayette County officials purchased the former Remann House in 1932 and began remodelling it for their own purposes; offices moved into the new courthouse in the following year. As the twentieth century passed, the Remann House gradually became too small for the county's needs, so several adjacent buildings were purchased or constructed.
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Loton Hall, 1796 The estate is mentioned in the Domesday Book. The core of the present house dates from the 17th century, though significant remodelling was carried out throughout the 19th century. The ruins of an earlier castle, built in 1340, survive in the grounds. The north front was built in 1712 by Sir Edward Leighton, 2nd Baronet, who moved his family seat here from Wattlesborough Castle, and was High Sheriff of Shropshire for 1727.
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Grant regained the castle, and was also awarded Cameron lands as recompense. The Great Raid proved to be the last raid. In 1527, the historian Hector Boece wrote of the "rewinous wallis" of Urquhart, but by the close of the 16th century Urquhart had been rebuilt by the Grants, now a powerful force in the Highlands. Repairs and remodelling continued as late as 1623, although the castle was no longer a favoured residence.
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There are ceilings by Robert AdamLord Coventry also employed Adam in the country, at his seat of Croome Court, Worcestershire. in rooms on the piano nobile. Thomas Cundy the Elder effected some remodelling, probably in 1810-11.Pevsner, ibid.. According to Charles Dickens, Jr., writing in 1879:Charles Dickens, Jr., Dickens's Dictionary of London (1879) During the Second World War, the club was briefly the home of Ian Fleming, the creator of James Bond.
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Monuments and monumental inscriptions in Scotland: The Grampian Society, 1871 This remodelling featured major new tree-planting which took many years to re-establish. The central open space is a private garden, available to owners of the surrounding properties. For the last three weeks in August each year Charlotte Square gardens are the site of the Edinburgh International Book Festival. The railings around the gardens were removed in 1940 as part of the war effort.
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The Peacock Room was originally designed as a dining room in the townhouse located at in the neighbourhood of Kensington in London, and owned by the British shipping magnate Frederick Richards Leyland. Leyland engaged the British architect Richard Norman Shaw to remodel and redecorate his home. Shaw entrusted the remodelling of the dining room to , another British architect experienced in the Anglo-Japanese style. Jeckyll conceived the dining room as a Porsellanzimmer (porcelain room).
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He was subsequently replaced by Samuel Barret, who constructed the towers in the extreme western end of the dormitories. Similarly and inexplicably, Barret was replaced by the Italian scenery designers Rambois and Cinatti, who had worked on the design of the São Carlos Theatre, to continue the remodelling within the monastery in 1867. Between 1867 and 1868, they profoundly altered the annex and façade of the Church, which then appeared as it does today.
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Gage's wife died on 25 July 1749, and on 26 December 1750 he married secondly Jane Godfrey, a Gloucestershire heiress.Alden (1948), p. 8 He had extensive remodelling work done on Firle Place and between 1743 and 1753, and was involved in a number of land rights disputes regarding windfall trees, soil rights, and manorial waste. Gage also spent considerable time collecting paintings which are still housed in the Long Gallery of Firle Place today.
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Another staircase, developed on one wall of the battery, leads to a paved terrace and parapet, which served as a musket firing line. The remodelling that occurred at the 18th century, altered the interior plan of the fort. Public works expanded the central compartment, reorganized the main courtyard and enlarged the cistern. Similarly, these public works were responsible for the construction of a breakwater on the rocky outcrops to protect the foundations of the fort.
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The rectangular detention block in the middle of the castle commons originally had three levels, but the two upper levels were destroyed in the 1531 earthquake. Remodelling completed in the 19th century took from the character of the façade. The first line of walls are reinforced by cylindrical towers and interrupted by vertical openings. The castle's bastions, completed in the 18th century, are distributed around the older part of the settlement of Abrantes.
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The screw-root form design is directly threaded into bone and has macroscopic retentive elements for initial bone fixation. A direct connection between bone and the implant provides high initial stability. Over time, screw-root form designs experience bone resorption and “bone modelling and remodelling at the bone to implant interface”. Plateau-root form dental implants of 3 different sizes Plateau-root form designed implants have a different healing process to screw-root form designs.
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Wilhelminische Veste (1860) Already as crown prince in Landshut, William V patronised the arts. His court architect Friedrich Sustris was in charge of the decoration and remodelling of Trausnitz Castle in Landshut. Later when he ascended to rule, Sustris also undertook the expansion of the Munich Residenz, the construction of the adjoining college, the palace Wilhelminische Veste (the so-called Maxburg) in Munich, and St. Michael's Church. In 1589, William V built the Hofbräu Brewery.
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Today's appearance of the oval and round Chinese Cabinet are closely connected to the remodelling of the palace initiated by the Austrian empress Maria Theresia. In 1743 she took the decision to change the former Schönbrunn hunting lot in the Habsburgian summer residence. This brought a change in the interior design from baroque to the nowadays-Rococo decoration. The architect Nikolaus Pacassi was responsible for three phases of reconstruction between 1743 and 1764.
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Homocysteine, a non-protein amino acid and analogue to the protein amino acid cystine, has been shown to have negative effects on bone health. Higher homocysteine concentrations are likely a result of folate, vitamin B12 B6 deficiencies. In addition, it was found that homocysteine concentration was significantly affected by physical activity. The stimulation of the skeleton through physical activity promotes positive bone remodelling and decreases levels of homocysteine, independently from nutritional intake.
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The fire opened the way for a more formal completion of the Scottish Law Courts in Parliament Square. This had been proposed as early as 1807, but blocked since 1810 by owners on the east side of the square. The fire destroyed the buildings they had been trying to retain and may have been viewed as a "happy accident". The remodelling of the buildings was completed to the original plan in 1829.
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The school had a £15m remodelling in 2011, as part of the London Borough of Newham’s Building Schools for the Future Programme. This included the introduction of a new four court sports hall, an open plan breakout space and a new passenger lift and staircase. The school also has an on-site fitness suite/gym, including separate facilities for muscular and cardio workouts. It is open to the public outside of school hours.
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The terminal opened officially March 15, 1979. The airport had been known simply as the Lagos International Airport. It was, however, renamed for the late Nigerian Head of State, General Murtala Muhammed, who died in 1976. The airport terminal has been renovated several times since the 1970s but its most radical makeover began in 2013, following the launch of the Federal government's multi-billion naira Remodelling/ Rehabilitation Programme for its airports nationwide.
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The church stands in the Exchequer near the site of a Saxon church, St Mary's, (which is believed to be under the present cathedral building) mentioned in the Domesday book. The current building dates from the late twelfth/early thirteenth century, was opened in 1317 and was rebuilt in 1695, following damage by the Parliamentary forces in 1644. In 1882 George Frederick Bodley undertook some remodelling work including a chancel screen and organ case.
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The specialisms of the new school would be Mathematics, and Design and Technology. Amongst changes made on Academy formation was the remodelling of the house system, five houses each with ten vertical tutor groups. There was uniform change from green sweatshirts to black blazers, the introduction of Head boy and girl along with a prefect system (year 10, 11 and 16+ students). The academy also has an academy council for years 7–11.
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It is no longer used and it is heritage-listed along with an outbuilding. Before the remodelling, the station had a platform next to the station building and an island platform, which was offset to the north. On the east side of the tracks, there were facilities for freight transport. For a short time in the 1940s there was a suburban platform on the west side of the station built on an embankment.
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António Santos Júnior became director general of the Coliseu dos Recreios in the same year. On the death of António Santos (1920), the direction of the Coliseu was assumed by Ricardo Covões. A major refurbishment of the installations was completed in February 1994, that included remodelling of the hall and stage, and reconstruction of the surrounding spaces. On 22 August 2006, the Coliseu (owing to its stylistic, typological and historic importance) was designated for preservation.
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The organ is built by the John Compton Organ Company, and arguably their finest work. It was ready for the rededication of the church in November 1957. It has recently been completely overhauled and cleaned by Keith Bance, who has carried out some modest tonal updating. This included remodelling the positive division, adding new mixture stops to the great and pedal divisions and the provision of a new Vox Humana for the solo division.
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The interior, designed by Guy Allbut, originally comprised a demonstration theatre, showroom, offices and staff accommodation. In 1959, when Shortland County Council became responsible for electricity supply in the Hunter Region, they constructed a three-storey extension at the back of the building. A tower was added in 1967 and remodelling was carried out in 1969 and 1970. After the council vacated the building in 1987, a radio station and an architectural practice moved in.
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This work started in the winter of 1999-2000 but was not complete when the 2000 Season started, so a temporary terminus - Kingsway Halt - was used to enable services to start. The terminus had no nameboard, just a stretch of gravel and a handwritten notice on a chalkboard. The line's overall length became . 08: With the remodelling complete the temporary northern terminus closed and its permanent replacement opened on 11 July 2000.
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Pancreatic stellate cells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. PaSCs are mediated by paracrine and autocrine stimuli and share similarities with the hepatic stellate cell. Pancreatic stellate cell activation and expression of matrix molecules constitute the complex process that induces pancreatic fibrosis. Synthesis, deposition, maturation and remodelling of the fibrous connective tissue can be protective, however when persistent it impedes regular pancreatic function.
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Rubin designed numerous residential complexes in Tel Aviv. One of these buildings, Rothschild Boulevard 85, designed in 1932, sold for 7 million dollars in 2007. One of Rubin's important designs was his remodelling of the building that became Israel's Independence Hall (at Rothschild Boulevard 16). In 1932, Rubin resigned the home of Mayor of Tel Aviv Me'ir Dizengoff, who donated it to the city as the first home of the Tel Aviv Museum of Art.
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He sailed from Southampton on 21 September 1907 to take up a professional position in America. Barker served as head professional at Garden City Golf Club in Garden City, New York, from 1908 to 1911. He found golf to be more competitive in America and failed to win any events. But he also discovered less challenging courses and soon began designing and remodelling layouts with the intention of elevating the game in the United States.
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Electrification on the Railway system in the eastern region necessitated major repair and overhaul facilities for Electric Loco, EMU Rolling Stock from early 60's. Kanchrapara was selected to play the key role in these spheres. In 1962 a decision was taken for remodelling Kanchrapara Workshop in order to make it a base workshop for electric locos, electrical multiple unit stocks of Eastern and South Eastern Railways. With this, the station was established.
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The central tower appears to date from the early 13th century. It was substantially reconstructed in the early 14th century during the remodelling of the east end, necessitating the internal bracing of the piers a decade or so later. In the 14th century the tower was given a timber and lead spire which burnt down in 1439. The exterior was then reworked in the Perpendicular style and given the present parapet and pinnacles.
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59 According to speculation, the sale was motivated by financial issues and a personal distaste of the building.Dean, p.58 It remained empty until 1882 when it was purchased by Thomas Nevill, a local industrialist whose wealth came from calico printing, for his son, Charles.Riley, p.29 While living in the house, Charles Nevill carried out substantial restoration and remodelling, making the interior more comfortable while retaining most of the building's external features.
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Troisi's design was chosen, and the ceremony was held on 30 June 1720. Zondadari was succeeded by Vilhena in 1722, and Troisi was once again commissioned to design a triumphal arch which was to be made by remodelling the 1720 arch. Troisi made the designs and supervised its construction, while the woodwork was done by Andrea Camilleri and the painting was renewed by Aloisio Buhagiar. Vilhena's possesso was held on 20 September 1722.
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On 13 June 2011, M&M;'s World store in London opened to the public, in Leicester Square. The site was formerly occupied by the Swiss Centre. It is the world's largest candy store, at 35,000 sq ft (3,250 sq metres). The retail space was built as part of Westminster City Council's regeneration of the local area, to create a "world class destination", based on the similar remodelling of Times Square New York.
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Elizabeth line trains will call at Hanwell, with services through Central London to Southeast London and Essex planned to commence in mid-2022. Selective Door Opening will be used because the platforms are shorter than the Crossrail trains will be. Full step-free access from street to platform level will be realised in 2020 with the completion of work (including remodelling of the station forecourt) by Ealing Council, following a consultation in 2019.
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Joanna Martin (London: Hambledon Press, 1998), p. 346. in 1815 he assumed the additional name of Wyndham in right of his wife, becoming Windham Wyndham-Quin. Caroline began remodelling the building in 1858; the central tower was replaced by a conservatory and the north and south wings were enlarged by Egbert Moxham. It was inherited by Edwin Wyndham-Quin, 3rd Earl of Dunraven and Mount-Earl, MP for Glamorganshire 1837–1851, and descendants.
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He was behind a remodelling of the store which took place between 1939-40. A further store was opened in Newton Abbot. In 1948, D H Evans purchased the business for £259,556 but continued to operate the business as a separate entity from the Oxford Street store. In 1954, however, Harrods completed the purchase of the entire preference share capital of DH Evans (they had owned the entire ordinary share capital since 1928).
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The house was built in the early 17th century, when the manor was owned by the Earls of Suffolk. In 1641, it was sold to Sir John Strangways. It remained in the possession of the Strangways, who in 1756 became Earls of Ilchester, until 1911 when it was sold to Captain Gerald Carter. The gardens were laid out by Percy Richard Morley Horder when he undertook remodelling of the house in 1911.
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The State of Berlin hired a consortium composed of Walter Bau AG and DYWIDAG that won the €45 million franchise. The consortium took charge of the operation of the facilities together with Hertha BSC and the Government of Berlin after the remodelling. On 3 July 2000, the renovation began with a ceremony presided over by the Chancellor Gerhard Schröder, accompanied by Eberhard Diepgen (Mayor of Berlin), Franz Beckenbauer and Prof. Dr. Ignaz Walter.
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View of the Hudson River from Wilderstein The mansion commissioned for the site was a two-storey Italianate villa designed by architect John Warren Ritch. In 1888, Thomas Suckley's son Robert Bowne Suckley and his wife, Elizabeth Philips Montgomery, undertook a remodelling and enlargement of the house. This work was carried out by the local architect Arnout Cannon from Poughkeepsie. The style of the mansion was changed to a Queen Anne style country house.
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Matcham rarely ventured away from theatres, but did on occasion. He was commissioned by the Blackpool Tower Company, a Standard Contract & Debenture Corporation, to design the decoration for the ballroom, which formed part of their entertainment complex in Blackpool, Lancashire.Walker, p. 127. The ballroom's interior was Matcham's only design for the complex, although Historic England consider it probable that he was also responsible for the remodelling of the circus, also within the complex, in 1900.
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Before that time he had been working in Arnstadt, where he played the Wender organ of the Neue Kirche. After he moved to Weimar in mid 1708, he revisited Mühlhausen several times in the next few years, for instance supervising the remodelling of the organ of the Divi Blasii according to his design, which was completed in 1709, and performing cantatas he composed for council election in 1709 and 1710 (BWV 1138.1 and 1138.2).
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Most passenger services passing Banbury stop at the station, and heritage trains stop here to fill up on water. Many redundant loops and sidings surround the station: most of these were for goods services stopping at Banbury, which have all disappeared. Two goods loops survive to allow the stoppage of goods trains for the uninterrupted passage of passenger trains. The station is being considered for remodelling to improve operational flexibility by Network Rail.
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The roofline is lower than that of the Great hall section, which is partly covered with slabs of Horsham stone, a material used often in the area. The 18th-century work added a new wing on the west side; changes were made at the northern end in the following century; and the most recent remodelling in 1936 resulted in more changes on this side. The windows were, until recently, boarded up but most were modern.
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The tower is thought to have been constructed in the 13th century AD, although the additional two storeys with corner fireplaces that were subsequently added to it, date from a 1574 remodelling by Sir John MacOliver Burke. There are loops in the battered base, and the entrance has a drawbar slot. The castle was mortgaged to the Blakes in 1629, and leased by them to John Darcy in 1668. The present tower house was built in the 16th century.
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Further renovations were done in 1952 and the 1960s, adding verandahs to the two clubhouses (one of which dates to 1808 and was used as a warden's house) and remodelling their interiors. Though the club's lease was initially year-to- year, in 1956 it began a 99-year lease from the Department of National Defence. The club dredged Melville Cove, added a "marine railway", and created a large marina, at which dozens of boats are now docked.
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From 1970, Madresfield Court was the home of Rosalind, Lady Morrison, William and Mona's niece and, as of 2012, it is run and lived in by her daughter, Lucy Chenevix-Trench. In 2014, an extensive remodelling of the interior of the house was undertaken by the interior designers Todhunter Earle. Madresfield Court has never been sold or bought in its history, passing by inheritance through the Lygon family, although on three occasions this has been through the female line.
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The town had a similar though smaller role during the Second World War and, in recognition of this, the Royal Engineers were presented with the Freedom of the City in 1947. Since the War, Ripon has gone through some remodelling and has grown in size; it attracts thousands of tourists each year who come to see its famous buildings with their long Christian heritage, nearby Studley Park, Ripon Racecourse, and in recent times the theme park Lightwater Valley.
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During pregnancy relaxin has a diverse range of effects, including the production and remodelling of collagen thus increasing the elasticity of muscles, tendons, ligaments and tissues of the birth canal in view of delivery. Although relaxin's main cellular action in pregnancy is to remodel collagen by biosynthesis (thus facilitating the changes of connective tissue) it does not seem to generate musculoskeletal problems. European Research has determined that relaxin levels are not a predictor of PGP during pregnancy.
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Similar to the room running off the Dining Room on the ground floor and part of the same remodelling undertaken by the 1st Viscount Preston. The mezzotint female portraits are late eighteenth century after the style of Reynolds and form part of a collection given to the National Trust by Kathleen Cooper-Abbs owner and donor of Mount Grace Priory. The miniature walnut-veneered bureau is likely to be either an apprentice's masterpiece or a furniture's salesman's showpiece.
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Cysteine protease ATG4A is an enzyme that in humans is encoded by the ATG4A gene. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodelling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.
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On 12 January 1791, Pierre Leon and Kléber were both called as expert witnesses for a remodelling project in the secularized Masevaux Abbey.Pirmin Tresch: Histoire de Masevaux: Abbaye et Sanctuaires, Oberlin, Strasbourg 1987, p.214. Strolz's parents had Jean- Baptiste trained for a career as a lawyer,Robert, Adolphe, Bourloton, Edgar, Cougny, Gaston: Dictionnaire des Parlementaires Français, Bourloton (ed.), Paris 1889, p. 414 but he gave up his studies when called home by his parents during the French Revolution.
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Scarring takes place in response to damaged or missing tissue following injury due to biological processes or wounding: it is a process that occurs in order to replace the lost tissue. The process of scarring is complex, it involves the inflammatory response and remodelling amongst other cell activities. Many growth factors and cytokines are also involved in the process, as well as extracellular matrix interactions. Mast cells are one cell type which act to promote scarring.
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Demolition of blocks built in the 1950s and remodelling of the remainder created the Bursar Primary Academy, replacing Bursar Primary School.Note: Relative locations of the two sites can be seen in Google Maps here. The buildings were significantly modified for the new use, while retaining much of the character of the old school. The primary school opened in September 2018 on the site of what used to be Humberstone Foundation School with an initial capacity of 315 pupils.
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He drafted plans, proposing a potential Neoclassical remodelling of the structure. Burdon in the end chose not to commission him. The Nimmo family would go on in 1826 to found what would come to be known as the Castle Eden Brewery, trading as J. Nimmo and Son Limited. Other families such as the Savilles owned their rope works and bleachery for sail cloth manufacturing, making the village, at the start of the 19th century, a fairly industrious one.
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The tithe barn in Amorbach, built in 1488, has for five hundred years played a central role in the town. Originally built to store tithes in the form of produce for the prince, it was – after extensive remodelling in the 1960s – run as a cinema. The Kulturkreis Zehntscheuer Amorbach e.V. (“Amorbach Tithe Barn Cultural Circle”), which outfitted the building in 1991 as a cabaret theatre maintains and renovates the building, which stands in the historical town centre.
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At the heart, AT1 blockage decreases contractility and the stimulatory effects of the sympathetic nervous system. Collectively, fimasartain leads to a reduction in blood pressure and alleviation of hypertensive symptoms. ARBs like fimasartan have also shown to be protective against stroke, myocardial infarction, and heart failure. Fimasartan has been shown to reduce cardiac hypertrophy, fibrosis, remodelling, and unnecessary cell proliferation via blockage of AT1 activation conceivably through decreased Endothelin 1 production, a result of AT1 activation.
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The BCL11A gene encodes for a regulatory C2H2 type zinc-finger protein, that can bind to the DNA. Five alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been reported. The protein associates with the SWI/SNF complex, that regulates gene expression via chromatin remodelling. BCL11A is highly expressed in several hematopoietic lineages, and plays a role in the switch from γ- to β-globin expression during the fetal to adult erythropoiesis transition.
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The current Romantic Gothic appearance dates from 1849 to 1860, when partial remodelling in this style was carried out according to plans by Bernard Gruber. The Early Gothic style castle of Orlík was confiscated by the Communist Regime after 1948, but in 1990s was reverted to the Schwarzenbergs. Access to the chateâu is by a stone bridge across the moat. Three round towers rise above the main façade, one of them being the original, built in the 14th century.
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Cambodge, however, was bought by Sun Lines, a Greek cruise line, for conversion into a cruise ship. In 1970 Cambodge sailed to La Spezia in northern Italy, where she was renamed Stella V and her interiors were partially gutted for a massive planned remodelling. When plans were completed, Stella V sailed to Perama, in southern Greece for conversion into Stella Solaris. Her passenger accommodations were revised to 765—all first class—and nearly twice the original capacity.
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The structural arrangement of the castle through remodelling, which was carried out several times later on, is an example of the Czech Early Gothic castle architecture. The arrangement is highly intricate and leads in one direction towards the front moat, to which both the wedge-shaped round towers pointed. The outer tower, above the moat, was later merged with the body of the castle, while the other tower stands alone at the rear of the inner court.
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Additions were made to the house, including the south-west wing to designs by David Hamilton, completed in 1831. In 1847 Sir William Stirling Maxwell inherited the estate, and began a remodelling of the house and grounds. Architects Alfred Jenoure and William Stirling II worked on the house, while formal gardens were laid out by James Niven. A chapel was added in 1912, designed by Rowand Anderson and Paul, and with interior mosaic decoration by Boris Anrep.
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Lanrick was the property of the Haldane family. In the 19th century it belonged to the MacGregors, and was owned in the later 19th century by Robert Jardine of Castlemilk, MP. The house was probably built around 1790, and Gothic additions in the style of James Gillespie Graham were made in around 1815. Further alterations were made in the later 19th century, and parts of the building underwent internal remodelling in 1900. Alistair Dickson inherited Lanrick in 1984.
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Lipson passed the RIBA entrance examination in 1924, and in the following year migrated to Australia. Following his arrivals in Sydney, Lipson was employed for a while in the Commonwealth Department of Works and Railways. During his tenure here he worked on a number of Commonwealth Bank buildings erected around the county at this time. Connected with this work was the remodelling of the bank's head office at the corner of Pitt Street and Martin Place.
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Lipson was retrenched from government employment in the early 1930s and went into private practice. One of the early significant commissions was the remodelling of The Daily Telegraph Building in 1933 for the Bank of New South Wales (extant and now known as the Trust Building). From the mid-1930s Lipson was in practice with Peter Kaad. The work of this firm was heavily influenced by the Dutch School of Architecture, in particular by the work of Willem Dudok.
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Investigation of the history of Nelson's Staircase Award-winning work at Brinton Hall includes remodelling of the west front and renovation of all interior rooms. In the grounds there are formal gardens, the hall also has a walled kitchen garden with a hot greenhouse. The property is surrounded by parkland with ha-ha wall, lake, woods and meadows. The village and some of its houses were once used as a backdrop for the BBC television series Dangerfield.
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The original spiral staircase was also removed as well as the projection box, which was moved to another part of the basement with an entrance right next to the auditorium entrance. The cash desk in the upper foyer was divided into two.Novák, s. 400–401. The cinema obtained equipment allowing panoramic 70mm film projection during the next round of remodelling and repairs, which took place in 1971–1973 based on a project prepared by architect Jaroslav Šmídek.
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There has been a school in Ellington for 156 years;, it now offers education for children aged 3 to 11. The original school building of 1837 is now the village library. To serve the ever-growing population a new school was built in 1976; it soon proved to be too small and remodelling and extension work took place in 1986. At that time the nursery accommodation was added, which facilitated the later provision of the Early Years Unit.
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Initially the coal was supplied from the Nottingham coalfields then latterly from South Wales or Avonmouth when the Northern coal pits were closed. The service from South Wales was usually operated by one Class 66 locomotive pulling 25 EWS Coal Cars. The service ran from Avonmouth in Bristol, down the main line, reversing at Didcot Parkway and into the power station. The connections to the main line were severed in mid-2018 in association with the Oxford area remodelling.
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Since 1973, there has existed a partnership between Ebernhahn and the French community of Marolles-les-Braults in the department of Sarthe. The official partnership meetings take place each year on Whitsun weekend, in Ebernhahn in even-numbered years and in Marolles- les-Braults in odd-numbered years. On 22 April 2007, the square outside the multi-purpose hall in Ebernhahn, after a thorough remodelling, was given the name Place Marolles as an expression of the partnership.
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Remodelling and reconstruction was only completed in 1726. The writings of friar Bartolomeu Ribeiro, around 1740, indicate that the population around São Roque had hardily grown in the intermediary. After the forced extinction of religious orders, during the Liberal government, the monks left the convent, and the building began to serve the state in various forms, including prison, courts, finance offices, theatre and cinema, as well as cultural and sports associations and the municipal office buildings.
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Loss of spine clustering is also a possibility as shown in some fear conditioning experiments, leading to the net loss of spines in the frontal association cortex, a region strongly associated in fear conditioning, which strongly correlates with memory on recall. Once spines were added after fear extinction had a similar orientation to the spines lost during the original fear conditioning.Lai, C. S. et al. Opposite effects of fear conditioning and extinction on dendritic spine remodelling.
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Cochrane was created Baron Cochrane of Cults in 1919. Further remodelling was undertaken in the 1920s by Reginald Fairlie, including the removal of the porte cochere to the west front. After the death of the 2nd Baron in 1968 the house was closed, and gradually fell into disrepair and ruin. There are no significant remains of the internal gothic design save a cast iron balustrade in the D-shaped main stairhall in the east side of the building.
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Eaglesfield is of ancient origin, and Blacket Tower is the former seat of an old Scottish Borders family, Clan Bell,a sept of Clan Douglas. There is some debate about the origin of the first element of the name which may derive from the Celtic word for a church, eglwys in modern Welsh, or eaglais in modern Scottish Gaelic. Springkell House, Palladian mansion of 1734. Additions of 1818 by architect Alexander Johnstone, alterations and interior remodelling in 1894.
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Broadbent contributed to the remodelling of Bridge Street in Warrington town centre, the site of the 1993 Warrington bomb attacks that killed two young children with a 'River Of Life' memorial. The design is intended to give hope for the future, and takes the form of a fountain - a "river" running down the street bringing healing and refreshment. He has created two versions of the 'Reconciliation Triangle'. The first, in 1989, represented connections between Liverpool, Glasgow and Dublin.
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RNA silencing-based resistance is a powerful tool for engineering resistant crops. The advantage of RNAi as a novel gene therapy against fungal, viral and bacterial infection in plants lies in the fact that it regulates gene expression via messenger RNA degradation, translation repression and chromatin remodelling through small non-coding RNAs. Mechanistically, the silencing processes are guided by processing products of the double-stranded RNA (dsRNA) trigger, which are known as small interfering RNAs and microRNAs.
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The area is part of the traditional region of Lower Carniola and is now included in the Southeast Slovenia Statistical Region.Črnomelj municipal site The local church, built on the southern outskirts of the village, is dedicated to Saint Oswald () and belongs to the Parish of Dragatuš. It was first mentioned in written documents dating to 1526, but owes its current Baroque look to a major remodelling in the 18th century. The main altar dates to 1876.
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On first appearances the building appears to be entirely medieval, but in fact some of the exterior is a Victorian reconstruction. The remodelling of the house was undertaken at the end of the nineteenth century and the original bricks were restored to the front facade of the house. The interior layout of the house is little changed from 1500. The oldest part of the house is the panelled parlour, which contains some very fine examples of antique furniture.
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The original terminus of the line was in the western part of present-day Hanau West station, north-west of Philippsruher Allee. The entrance building was on the eastern side of the line, close to central Hanau. In the 1960s an underpass was constructed creating the current bridge over Philippsruher Allee which also supports the double track with one platform in the centre. During this remodelling the original entrance building designed by Julius Eugen Ruhl was demolished.
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The result was the identification of BAY 41-2272 and BAY 41-8543. Both compounds were tested in various preclinical studies on different animal models and appeared to improve systemic arterial oxygenation. To improve the pharmacologic and pharmacokinetic profile an additional 1000 compounds were screened leading to the discovery of riociguat. Riociguat was tested in mouse and rat disease models, where it effectively reduced pulmonary hypertension and reversed the associated right heart hypertrophy and ventricular remodelling.
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The old residence theatre, built in the Classicist style, stands opposite the park. It was probably built from 1819 to 1821 under the direction of the prince's master architect, W. Steinbach. In 1826 a remodelling was carried out under Schinkel's pupil, Johann Gottlieb Steinmeyer, in which gables were added above the ends of the building and over the portico. It was painstakingly restored from 1992 to 1998 and is one of the most dominant buildings in the town.
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Walter Dunch's widow, Deborah, subsequently married Sir James Mervyn (who served as High Sheriff of Wiltshire in 1596), and the couple were responsible for a major extension or remodelling of the house around 1601. In 1640 the Dunch family sold it to John Stawell, and the estate was sequestered when he was accused of treason in 1646. It was sold to George Long in 1652 but restored to Stawell in 1660 on his release from the Tower of London.
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He must have resealed it, hid the entrance and kept its location a secret, for whatever reasons, as it disappeared from public knowledge and was lost again, despite publication of the inscription. In 1780 the then owners of the vineyard, the brothers Sassi, who apparently had no idea it was there, broke into the tomb again during remodelling of their wine cellar.Lanciani (1897) pp. 322-324. They opened it to the leading scholars of the day.
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Research on the role of TRPC channels in cardiomyopathies is still in progress. An upregulation of TRPC1, TRPC3, and TRPC6 genes are seen in heart disease states including fibroblast formation and cardiovascular disease. The TRPC channels are suspected of responding to an overload of hormonal and mechanical stimulation in cardiovascular disease, contributing to pathological remodelling of the heart. TRPC1 channels are activated by receptors coupled to phospholipase C (PLC), mechanical stimulation, and depletion of intracellular calcium stores.
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NFAT translocate into the nucleus and induce gene transcription of more TRPC genes. This creates a positive feedback loop, leading to a state of hypertrophic gene expression and thus, cardiac growth and remodelling of the heart. TRPC channel's involvement in well studied signaling pathways and significance in gene impact on human diseases make it a potential target for drug therapy. TRPC has been shown to potentiate inhibition in the olfactory bulb circuit, providing a mechanism for improving olfactory abilities.
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In 2009, Sainsbury's became the new anchor tenant, replacing Curleys Supermarket that had been present since 1981. This led to a remodelling of the supermarket area of the shopping centre, leading to a Sainsbury's store that is approximately , and is its largest supermarket in Northern Ireland. There is also a Sainsbury's petrol filling station on the site at the Kennedy Centre. In October 2017 Sainsbury's opened their largest Argos concession in Northern Ireland within their West Belfast store.
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In 2018 The House of Garrard continued its rich legacy of sapphire jewellery creations with the unveiling of a 118.88ct royal blue Burmese sapphire presented in a brooch that features the House’s signature cluster setting. The jewel was named in honour of the 65th anniversary of Queen Elizabeth II’s coronation, a date traditionally marked by the gift of a sapphire, and pays tribute to the House’s role in remodelling the Imperial State Crown for the occasion.
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Inside the embryo, the dorsal aorta forms and eventually connect the heart to the capillary plexus of the yolk sac. This forms a closed-loop system of rigid endothelial tubing. Even this early in the process of vasculogenesis, before the onset of blood flow, sections of the tube system may express ephrins or neuropilins, genetic markers of arterial or venous identities, respectively. These identities are still somewhat flexible, but the initial characterization is important to the embryonic remodelling process.
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Additionally, biomechanic forces inside embryonic vessels have important remodelling effects. Pressure fluctuations lead to stress and strain fluctuations, which can "train" the vessels to bear loads later in the organism's development. The fusion of several small vessels can also generate large vessels in areas of the vascular tree where blood pressure and flow rate are larger. Murray's law is a relation between the radius of parent vessels to the radius of branches which holds true for the circulatory system.
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Between 1996 and 1998, the mausoleum was again renovated at a cost of about 27.5 million. When the Indian Ocean tsunami struck the seafront in December 2004, the memorial was damaged. Repair works cost approximately 13.3 million. Dr MGR Memorial in Kamarajar Promenade MGR's tomb and memorial at Marina beach before renovation In 2012, the memorial was again renovated at a cost of 43 million, including 34 million for remodelling the facade and the surrounding walll.
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In 1959 Shortland County Council assumed control of power supplies for the Hunter Region. In their new role they oversaw the construction of a three-story addition to the rear of N.E.S.C.A House. During their tenure they also added a decorative tower in 1967 and in 1969 the theatre and demonstration centre were remodelled. Further remodelling occurred in 1970 when two floors were added to the 1959 addition and the original council chamber was revitalised for new purposes.
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At the behest of The Prince of Wales, the artist Felix Kelly created an artist's impression of a remodeled Highgrove with neo-classical additions. Kelly had previously painted a vision of Henbury Hall in Henbury, Cheshire based on Andrea Palladio's Villa Rotonda. Kelly's artwork had formed the basis for the construction of Henbury Hall, and a similar painting of Highgrove subsequently formed the basis for a remodelling of the house in December 1987, undertaken by architect Peter Falconer.
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M. Ashley, The Glorious Revolution (London 1966) p. 112 This Quo Warranto remodelling or 'dissolution' of the parliamentary corporations gave point to the claim by William III that "our expedition is intended for no other design but to have a free and lawful parliament assembled", and underpinned the charge in the Bill of Rights that James had been "violating the freedom of election by members to serve in parliament".M. Ashley, The Glorious Revolution (London 1966) pp. 205–207.
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By mid-1998, the programme's middling ratings prompted the show's makers to drastically revamp the series. Brian Park, famous for his overhaul of ITV's Coronation Street, was appointed as Family Affairs' new producer and was tasked with remodelling the series. It was decided that the majority of the regular characters would be written out – including all members of Hart and Gates families. Throughout 1998, Tim, Susie and Liam departed, and the recurring Cockerill couple was phased out.
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The campus encompasses , 20 buildings, a fishing lake, a fitness trail, basketball, tennis and racquetball courts, and a rodeo arena. The Student Union is the heart of the campus. It contains the Conq Corral (snack bar, computer center, 4 satellite televisions, and entertainment center), Conq Shop Bookstore (currently in the upper level), Journalism Department, Student Government Association, and Information Center. It is currently under remodelling and its services are currently located in the Learning Resource Center. See www.dc3.
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Eukaryotic genomes are ubiquitously associated into chromatin; however, cells must spatially and temporally regulate specific loci independently of bulk chromatin. In order to achieve the high level of control required to co-ordinate nuclear processes such as DNA replication, repair, and transcription, cells have developed a variety of means to locally and specifically modulate chromatin structure and function. This can involve covalent modification of histones, the incorporation of histone variants, and non-covalent remodelling by ATP-dependent remodeling enzymes.
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New houses included Oak Lea for Henry Schneider (1874, since demolished), Witherslack Hall (1874), and Hampsfield House (1880–82). Their last major work on a country house was the remodelling of Thurland Castle (1879–85) following severe damage by fire. The practice continued to design new schools, and in the 1870s they began to design new buildings for Sedbergh School, creating an association with the school that was to produce commissions throughout the remaining life of the practice.
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Following the rebellion against Queen Mary by Sir Thomas's son, Thomas Wyatt the younger, the property was forfeited back to the crown. Possession was later granted to Sir John Sedley by Mary's half- sister Queen Elizabeth. The Sedleys sold the estate to Sir Peter Ricaut and his family. Although the Sedley family made some changes to the priory, it was the next owner, Sir John Banks, in the 1670s, who was responsible for the remodelling of the buildings.
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This comprised the extension of the northern and southern wings of the building and the remodelling of the existing portions of these wings. In the following year, a further worth of additions was authorised; this consisted of an extra storey erected over the central block, and alterations to the lower level of this block. The extensions were completed in 1939. The changing character of Brisbane's inner suburbs away from family homes has resulted in falling enrolments.
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In the 1880s it was determined that the land where Ingelside Cemetery was located could be better used for housing. Most of the bodies there were moved up the mountain to Mount Moriah and re-interred. However, since many graves were unmarked or unknown some were not moved. Today it is not uncommon for people working in their garden or remodelling a basement or shed to find human bones as a leftover from the Ingelside Cemetery days.
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The monastery was expanded in the twelfth century. Several kings of Navarre were buried there. Since then it has been in various states of repair, undergoing many expansions and remodelling (the most extensive carried out in the sixteenth century, when almost the entire monastery was rebuilt). Romanesque architecture pieces have survived until the present day (such as the church, with its Porta Speciosa), as well as parts that are even more ancient such as the notable crypt.
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The IPPAR consultative council favoured its establishment as a Imóvel de Interesse Público (Property of Public Interest) pm 24 March 1994. In 1995, Lello & Irmão created a new society: Prólogo Livreiros S.A., which preceded its reopening on 15 March 1995, following a period of restoration and remodelling. The Secretary-of-State for Culture solicited a presentation on 14 March 201 to establish a special protection zone (ZEP) the site, which was supplemented by the DRCNorte (on 12 April).
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The Thameslink Programme (formerly known as Thameslink 2000), is a £3.5 billion major project to expand the Thameslink network from 51 to 172 stations extending northwards to Bedford, Peterborough, Cambridge and King's Lynn and southwards to Guildford, Eastbourne, Horsham, Hove to Littlehampton, East Grinstead, Ashford and Dartford. The project includes the lengthening of platforms, station remodelling, new railway infrastructure (e.g. viaducts) and additional rolling stock. The new Thameslink timetable for Norwood Junction started 20 May 2018.
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The raids by the Picts and Scots in the late 4th and early 5th centuries (the so-called 'Pictish Wars'), meant increasing strain. For example, between 385 and 398 (when Stilicho cleared the raiders out), Cumbria was 'left to its own devices'.Higham (1986), p. 240. The various phases of remodelling of the Birdoswald fort in the second half of the 4th century suggest that it was becoming more like a local warlord's fortress than a typical Roman fort.
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It was added to in 1690 (with stone quarried from Dryburgh Abbey), in 1761 (West wing), and 1796 (East wing). Further alterations in 1841 and 1859 (the replacement of the West wing) were followed by alterations in 1923. Between 1959-61 what has been described as a "fashionable reduction and remodelling" took place which removed the servants wing to the north and modified that to the West, restoring more of the dominant character of the Great Tower.
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His lavish spending was immortalized by Augustus' reported question to the viceroy "Brühl, do I have money?" By 1748 Augustus III completed extending the Saxon Palace in Warsaw and made significant contributions in remodelling the Royal Castle. In 1750, von Brühl purchased a residence adjacent to the larger Saxon Palace and transformed it into a rococo masterpiece, which later became known as the Brühl Palace. Both buildings were completely destroyed by the Nazis during World War II.
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Here he advised on the rehabilitation of the county's older schools and added library and drama facilities. He also worked on several historic buildings, adapting All Saints, Lewes, in East Sussex, into a theatre; a school in Dulwich, London, into housing; and remodelling Chelsea Town Hall. Still active well into his 70s, Finch formed a professional practice with his then partner, Kate Macintosh. In 2005 Finch Macintosh designed the Weston Adventure Playground, Southampton, a charity lottery project.
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Kirti Nagar is one of the most affluent neighborhoods in all of Delhi, India. Part of the Punjabi Bagh subzone of West Delhi, it primarily a residential colony. Kirti Nagar is home to India's largest furniture market housing showrooms of multi-national home remodelling and fittings companies, the most reputed interior design boutiques, imported kitchen and bath brands as well as traditional carpentry furniture makers. Kirti nagar also hosts the biggest golf course and country club in North India.
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Extracted from "Brooks Green", GetOutside, Ordnance Survey. Retrieved 13 June 2020Extracted from Brooks Green,Google Maps 2020. Retrieved 13 June 2020 Approximately south-east from the central junction, and south off Lackenhurst Lane, is the farmhouse of Lackenhurst, Grade II listed in 1959, which dates to the 16th century and is timber-framed, of two storeys, with a half-hipped gabled roof of Horsham Stone slabs."Renovation and Remodelling a C16 Sussex Farmhouse" (Lackenhurst), Pullen Architecture.
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The White House in the background of The Family of Frederick, Prince of Wales, a 1751 group portrait of Frederick's widow and children by George Knapton. Frederick began remodelling the gardens associated with the White House, but "after staying all day in the garden till night, in the damp rain and hail to look at his workmen" in 1751 he caught a chill which – combined with a pulmonary embolism – proved fatal.BBC4 – Frederick, Prince of WalesNatalie Livingstone, The Mistresses of Cliveden (Random House, 2015), chapter 6 His widow Augusta continued living at the White House with their children and remodelling the gardens. She was advised by her husband's friend John Stuart, 3rd Earl of Bute and assisted by Sir William Chambers, one of the greatest masters of ornamental English gardening. Frederick's sister Amelia was probably still in the Dutch House throughout the 1730s and 1740s, but seems to have moved out in 1751 when she was made ranger of Richmond Park, which came with a residence at White Lodge.
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The official picture taken after the signing of the Lisbon Treaty in front of the South Portal The Minister of Public Works (Ministério das Obras Públicas) opened a competition to finish the annex, which would serve as the National Museum of Industry and Commerce (Museu Nacional da Indústria e Comércio), but the project was canceled in 1899, and the Ethnological Museum of Portugal (Museu Etnológico Português) was installed. Further remodelling of the monastery was begun in 1898 subsequent to the work done by Parente da Silva in 1895 on the central annex, now simplified, as well as restoration of the (the chairs used by the clergy in religious services), which were completed in 1924 by sculptor Costa Mota. In 1938 the organ in the high choir was dismantled at the same time that a series of stained-glass windows, designed by Abel Manta and executed by Ricardo Leone, were replaced in the southern façade. As part of the celebrations marking the centenary of modern Portugal in 1939, yet more remodelling was completed in the monastery and tower.
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Since 2001, Thomas Lecuit has been studying how genes orchestrate the cellular movements that cause changes in the shape of embryonic tissues. His research includes characterization of the physical principles of morphogenesis, along the lines of the work begun by d'Arcy Thompson in On Growth and Form (1917)D’Arcy Wentworth Thompson, On Growth and Form, 1re éd., Cambridge (UK), Cambridge university Press, 1917; Forme et croissance, trad. de Dominique teyssié, seuil, coll. « science ouverte » 2009.His team first discovered the nature of the mechanical forces that cause tissue plasticity, namely the contractile forces that reshape the shape and cellular interactionsBertet C, Sulak L, Lecuit T, « Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation », Nature, 2004 jun 10;429(6992), p. 667-71Rauzi, M., Verant, P., Lecuit, T. and Lenne, PF, « Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis », Nature Cell Biology, 2008 dec;10(12), p. 1401-10Rauzi, M., Lenne PF., and Lecuit, T, « Planar polarized actomyosin contractile flows control epithelial junction remodelling », Nature, 2010.
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Argentina and Ghana in 2009. This picture was taken before remodeling. During 2010 and 2011 the stadium went through a remodelling process. The field was sunken 4 meters, the iconic Autotrol scoreboards installed for the 1978 World Cup were replaced with modern video screens, new bleachers were built in order to improve the poor view caused by the shallow shape of the stadium and the capacity was increased to 57,000, becoming the third largest stadium in Argentina by seating capacity.
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Immature dendritic cells (DCs) can phagocytose, but mature DCs cannot due to changes in Rho GTPases involved in cytoskeleton remodelling. The phagosomes of DCs are less hydrolytic and acidic than those of macrophages and neutrophils, as DCs are mainly involved in antigen presentation rather than pathogen degradation. They need to retain protein fragments of a suitable size for specific bacterial recognition, so the peptides are only partially degraded. Peptides from the bacteria are trafficked to the Major Histocompatibility Complex (MHC).
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The cost of the remodelling was reported as exceeding £25,000. The largest of the new buildings, built to receive, process and churn cream, was constructed of reinforced concrete with a tubular truss roof, crowned by a lantern roof. The engine/plant room was built to the rear of the larger structure. The new buildings were officially opened on 9 March 1929 by William Forgan Smith, Minister for Agriculture and Stock, with over 1000 invited guests and the township "en-fete" for the occasion.
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The Astor Theatre remodelling was Village Theatres' first Queensland venture and second twin cinema complex, and possibly the third multi-screen cinema to be constructed in Australia. In the conversion, Monsborough economically adapted the existing volume of the early cinema to create two smaller yet spacious theatres under the one roof. The cinemas are located back-to-back with a shared projection box between them. Drawings from the 1970 conversion indicate that the new ceilings were fixed to the existing curved, timber truss.
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Being crowned King of Sicily in Palermo in December 1713, he returned to Turin in September 1714. From Palermo he brought back Filippo Juvarra, an Italian architect who had spent many years in Rome. Juvarra was patronised by Victor Amadeus and was the mind behind the remodelling of the Royal Palace of Turin, Palace of Venaria, Palazzina di caccia of Stupinigi as well as building the Basilica of Superga. The architect was also responsible for various roads and piazza's in Turin.
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This was the first bank in Toodyay. The manager of the Northam Branch, James Mitchell, who later became the Premier of Western Australia and Governor of Western Australia, rode over twice a week to also manage the Toodyay branch. In 1898 the bank vacated the premises, moving into a newly constructed premises on Stirling Terrace, and the Monger family resumed occupancy. In 1910 the residence was acquired by Mr Angus and Mrs Emma Butterly (née Monger), who undertook extensive remodelling of the dwelling.
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Additional expansion occurred between 1937 and 1938 by James Forbes of Forbes and Tate. Hill's remodelling was carried out for the amateur architect Colonel Reggie Cooper and his wife. The house was the subject of the main article in the 4 June 1932 issue of Country Life, which included extensive photographs of the interior and exterior. The art historian and administrator Kenneth Clark and his family moved to the house in 1946 having previously lived at nearby Capo Di Monte on Judge's Walk.
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Boudewijn de Cock sold the castle in 1643 to Nicolaas Rubens, Lord of Rameyen, the second son of the famous painter Pieter Paul Rubens. The castle stayed as a property of the Rubens family until 1759. During the 17th century the castle underwent major restorations and remodelling but at the end of the same century the castle stood empty and decay started. The restoration took place in the 19th century when Esquire Nicolaas Joseph Alphonse de Cock came in possession of the castle.
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In medieval times Northwick was a collection of smallholder's cottages surrounding a mansion owned by the Childe family. In 1683 it was bought by Sir James Rushout, Bt, the son of a rich Flemish merchant, who carried out extensive remodelling in 1686. The 4th Baronet continued the work, commissioning the architect Lord Burlington to design a Palladian east front and entrance hall in the 1730s. The 5th Baronet, later Baron Northwick, employed architect John Woolfe to carry out further improvements c.
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Trail 1: Goddards Green and Church Wood, Historic landscape trails in Benenden, Benenden Amenity and Countryside Society. Retrieved 2017-12-02. The house, which featured a prominent tower and was described as having "alarming vitality", was built in an Elizabethan style and was subsequently remodelled in 1912 by Herbert Cescinsky at the behest of its new owner, newspaper magnate and later Lord Rothermere, Harold Harmsworth. The remodelling saw the "vitality" toned down and the upper levels of the tower removed.
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In the First World War the Royal Flying Corps had an airfield on the Westwood. The site is now Beverley Racecourse The Second World War saw the nearby city of Hull suffer significantly from aerial bombardment: however, Beverley was more fortunate and did not endure such heavy attacks. Since the war, Beverley has gone through some remodelling, and has grown in size. It attracts thousands of tourists each year who come to view the religious buildings and visit Beverley Racecourse.
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In 1490 Landgrave William I (1466–1515) "built a fine hunting lodge on the foundation walls of the original site, which was to be a venue for innumerable prestigious festivals and gatherings for 300 years". After this rebuilding or remodelling there was a significant requirement for drinking water for people and animals. This was the catalyst for the construction of a water pipe. In 1508 construction began on the palas, which was finished under his nephew Philip I (1504–1567) in 1519.
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Laporte and Fialko 1994, p.339. The deceased was interred upon the east–west axis running through the centre of the E-Group during the transition between the Late Preclassic and the Early Classic periods. The tomb was elite-status and was perhaps the earliest royal burial in the Mundo Perdido. Any funerary offerings were removed during the 6th century AD during remodelling of the temple, at which time the offerings were redeposited under the third chamber of the shrine.
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The current Georgian house is Grade II listed. It was originally built in 1725, but was later restored and remodelled by the architect Basil Ionides in 1940 following a fire. As part of the remodelling, Ionides introduced many original 18th century features salvaged from other properties including West Harling Hall in Norfolk and Chesterfield House, off Park Lane, London. During the Second World War, the Royal Society of Arts relocated its valuable library of books and records to Buxted Park for safekeeping.
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Around this time, William Adam was engaged on his first major commission, the remodelling of Hopetoun House for the Earl of Hopetoun. Clerk and Adam collaborated on the design of Mavisbank, which was based on the 1698 proposal. Each claimed the greater part of the credit for the design. Clerk wrote in a letter that he designed the house "under the correction of Mr Adam, a talented architect", while Adam credited the design to himself in his book, Vitruvius Scoticus.
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The Gasometers are four cylindrical telescopic gas containers, each with a volume of about 90,000 m³ seated in a water basin; each is enclosed by a red-brick facade. They are each 70 meters tall and 60 meters in diameter. The Gasometers were gutted during the remodelling and only the brick exterior and parts of the roof were left standing. Coal gas was dry-distilled from coal and was stored in these containers before it was distributed into the city gas network.
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25 By 1872, the Hope Valley Reservoir in the foothills of the Adelaide Hills was completed as a storage reservoir, supplied via an aqueduct and tunnel. Public baths were built in 1861 just north of the current Parliament House. They were supplied with reticulated water from the Torrens and progressively upgraded with the last change a 1940 remodelling including an Olympic size swimming pool and diving tower. The baths were demolished in 1970 to make way for the Adelaide Festival Centre.
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More changes were made in 1887, with several new interior fittings added, although a major remodelling and redesign proposed during the same year was not carried out. The designs were displayed at the Royal Academy, however. The church has seen little change since then, although a set of 17th-century altar rails taken from a Belgian church were installed in 1957. The church is licensed for worship in accordance with the Places of Worship Registration Act 1855 and has the registration number 8131.
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The descendants of Marshal Daun, the famous military leader, rebuilt the castle in the spirit of the Romantic style. Between 1811 and 1845 the richly-decorated state rooms were created, on the basis of proposals of Anton Schuler. The culmination of the re-Gothicising work was the remodelling of the Church of the Assumption of the Virgin (kostel Nanebevzetí Panny Marie) by Viennense architect Anton Rucker, who left the original Gothic furnishings. At the end of the 20th century, Bítov underwent extensive refurbishment.
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The abbey was partly destroyed in the Swedish invasion of Poland, and soon afterwards was rebuilt, with a new library. Further destruction took place during the Bar Confederation, when Polish rebels turned the abbey into their fortress. In 1816, Austrian authorities liquidated the abbey, and in 1821–1826, it was the seat of the Bishop of Tyniec, Grzegorz Tomasz Ziegler. The monks, however, did not return to the abbey until 1939, and in 1947, remodelling of the neglected complex was initiated.
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Bretton also has a water pump on a roadside green. The disappearance of the pump during remodelling of the road junction was a source of concern to local residents in the 1970s, until it was traced to a council storage yard and reinstated. Bretton Wood (south east of the village) is marked on Ordnance Survey maps of the area, in past times it was referred to as Bretton Forest,Page 22 The Place-names of East Flintshire. Hywel Wyn Owen.
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On 23 November 2006 Marks & Spencer announced a £35 million investment in its Northern Ireland business, £8 million of which was invested in its Forestside store. This involved remodelling, the addition of a second floor to add and a multi-storey car park. In 2012 Game closed its branch in Forestside along with many others across the UK after the company entered administration. In 2013 HMV closed its branch in Forestside along with 65 others across the UK after the company entered administration.
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Commemorative plaques of 1728 and 1731, translated from old to new Jerusalem Church The old church building housed a famous organ, a masterpiece built by Wilhelm Sauer and often played in concerts, which burnt on 3 February 1945. The typical Protestant Kanzelaltar, combining pulpit and altar table, was removed in the remodelling for orthodox liturgy, needing an iconostasis. Other, movable furnishings were translocated, when the church was closed in 1941. The carrara statue of Jesus of Nazareth, created in 1898 by Prof.
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Plan to build a new line between Beach and Egmore and two lines between Egmore and Tambaram was announced as part of the suburban remodelling initiative of South Indian Railways. On 27 December 1930, the first consignment of 25 electric carriages from England was received by the railway. The trains were painted in dull green with a black wheel base and featured wide sliding doors, a better-designed seating arrangement, and thick glass fronts. The new carriages were parked in Tambaram station.
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Other alternative injection routes have been studied, namely injection via sternotomy, endomyocardial and intracoronary routes. Nevertheless, all methods aforementioned have been associated with limited cardiac function improvements and limited cell survival once implanted in the fibrous myocardium. To resume, stem cells and delivery routes aforementioned are suitable for cardiomyoplasty as demonstrated safe with some degree of benefit for the patient. However, cardiac remodelling remains limited due to limited cell residency, impact of mechanical forces onto cell survival and tissue hypoxia.
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The hall was built in 1846 from Carn Brea granite and originally housed the town hall, magistrates and stannary courts, police offices, cells and the fire brigade. In 1909 plans were drawn up to change the building into a public hall. This culminated in it being leased for a skating rink and occasional picture house. In 1914 a fire gutted most of the building and in 1925 remodelling took place to accommodate a stage "suitable for the presentation of plays".
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In 1829, he prepared the design for the original Osgoode Hall; some remodelling and additions occurred later. He continued to operate a building yard and was a director on the boards of several institutions in the city after 1830, although he had retired as an architect. His daughter, Jane, was wife of Sir Oliver Mowat, and his son, Thomas Ewart, was married to Catherine Seaton Skirving, a noted philanthropist. He died in Toronto in 1856 of gangrene, brought on by arteriosclerosis.
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In three years the number was raised to 150 and Hartley was getting on so well with the staff and the boys that it appeared as though the college had found its ideal principal. However, in 1875 Hartley resigned to become president of the newly appointed council of education. Some four years later the council was abolished, and Hartley was appointed inspector-general of schools and permanent head of the South Australian Education Department. He immediately began remodelling the whole system.
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The area is part of the traditional region of Lower Carniola and is now included in the Southeast Slovenia Statistical Region.Črnomelj municipal site The local church is dedicated to Saint Roch () and belongs to the Parish of Vinica. It was first mentioned in written documents dating to 1526, but owes its current Baroque look to a major remodelling in the 18th century. The main altar dates to the 17th century, but was renovated and remodelled in 1825 and again in 1889.
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Pyramid A1, one of the principal structures of Group A Group A is located on the northern end of the ridge.Lehmann 1968, p.10. The group was extended during major remodelling work that included the building of the final versions of Platforms A2 and A3 on the north side; this involved building a new retaining wall some further north, east and southeast and filling in the area between the new and old walls to create a greatly expanded terrace.Lehmann 1968, pp.
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The Brandon-Bell-Collier House is a house in Fulton, Callaway County, Missouri, in the state of Missouri in the central United States. It was built in stages between about 1862 and 1917. From 1900 to 1902, it was owned by Fulton architect Morris Frederick Bell, who undertook a major remodelling, expanding the house to two stories and incorporating elements of the Queen Anne and Colonial Revival architectural styles. The house was listed on the National Register of Historic Places in 1998.
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He was the second surviving son of Samuel Child MP, and younger brother of Francis Child. In 1763, he succeeded his brother as nominal head of the family's bank, Child & Co., bringing him an annual income of over £30,000 (£ in ). He also inherited the estate of Osterley Park in Middlesex, where he continued his brother's project of remodelling the house to the designs of Robert Adam. Child contested Aylesbury at a by-election in 1764, but withdrew due to ill- health.
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Nairn, Pevsner and Cherry, The Buildings of England: Surrey, pp. 91, 166, 255–256, 273, 465, 484–485, 529. Numerous medieval churches exist in Surrey, but the county's parish churches are typically relatively small and simple, and experienced particularly widespread destruction and remodelling of their form in the course of Victorian restoration. Important medievalSee their highest grade I listings when searching for the places on the English Heritage Listed Buildings map church interiors survive at Chaldon, Lingfield, Stoke D'Abernon, Compton and Dunsfold.
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The Main Building reached its current form during a development program that commenced in the mid-1980s. At the beginning of the 1980s, the ever-increasing size of the school and the perennial problem of inadequate funding led to the remodelling of the administration of the school. A business manager was appointed and an Advisory Board established. In 1984, Civil & Civic commenced work on a Campus Development Strategy and a Foundation was established to raise funds for the proposed developments.
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51 Other historically significant details include a Norman window in the main bedroom, a 17th-century kitchen, and an "imposing" Tudor fireplace in the sitting room. Architectural historian Anthony Emery believes that the house originally consisted of a large single room on each floor with a vaulted chamber on the ground floor.Discovering medieval houses, Anthony Emery, Osprey Publishing, 2007, p. 30 Major remodelling was carried out in the 17th century being undertaken during the ownership of two generations of the Flower family.
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The side bays originally had four openings which were later replaced with false windows (these were also removed during the Neo-Baroque remodelling). The heavy cornice was supported by large projecting modillions. The western entrance was protected by an aedicular porch with two Ionic columns and a triangular pediment. The lower level of the tower was flanked by voluted gables with crosses, while the belfry on the upper level had four arched windows on each side with arched pediments and balconets.
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From 1989 to 1995 the corporation considered office or retail possibilities, until in 1995 it decided on a mixed-use development, to also include residential use, and named it Temple Quay. In December 1995, not yet having found a developer for the site, and about to be wound down, the corporation transferred its rights on the site to English Partnerships. In 1998 work began on remodelling the road access via Temple Gate. The developer eventually found for Temple Quay was Castlemore Securities.
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Founded in 1956, KORAY Holding is one of Turkey’s leading construction companies. With finished projects in Turkey, Jordan, Saudi Arabia, Azerbaijan, Libya, Kazakhstan and the Russian Federation, KORAY’s scope of work ranges from architectural design and turnkey construction of individual buildings to the master planning, architectural design and construction of entire communities, with special emphasis on turnkey construction of high-rise office buildings, commercial centers, headquarter buildings, 5 star hotels, university campuses and remodelling/renovation of bank branches according to changing corporate images.
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Residential design is the design of the interior of private residences. As this type design is very specific for individual situations, the needs and wants of the individual are paramount in this area of interior design. The interior designer may work on the project from the initial planning stage or may work on the remodelling of an existing structure. It is often a very involved process that takes months to fine-tune and create a space with the vision of the client.
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In 1993, a high-speed TGV train line was opened connecting Paris with Lille in one hour. This, with the opening of the Channel Tunnel in 1994 and the arrival of the Eurostar train put Lille at the centre of a triangle connecting Paris, London and Brussels. Work on Euralille, an urban remodelling project, began in 1991. The Euralille Centre was opened in 1994, and the remodeled district is now full of parks and modern buildings containing offices, shops and apartments.
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Palazzo Clary's facade on the fondamenta Zattere. Originally built in the late 17th century, during the vogue of the late Venetian Renaissance revival architecture, the palazzo underwent later remodelling in the 19th century but has kept its original style unchanged. The late Renaissance palace's façade onto the Zattere has become a very recognizable landmark of Dorsoduro: it is one of the most magnificent of the district and surely the most noticeable of the Zattere. The palazzo's architecture is typical of the Venetian Revival.
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The 1750s saw an extensive remodelling of the house with a new sitting room and staircase built and sash windows installed. Additional buildings were also built to the north but have since been demolished. From the late 18th century the estate was rented out to a number of merchants and farmers. By 1796 it had settled on the modern spelling of Sinai Park, apparently coined by William Burton in 1622 as an allusion to the Biblical wilderness which he alleged the estate resembled.
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Clarence House was also the official residence of Prince William from 2003 until April 2011, and of Prince Harry from 2003 until March 2012.Prince Harry moves into Kensington Palace It is open to visitors for approximately one month each summer, usually in August. The four-storey house is faced in pale stucco. Over the years, it has undergone extensive remodelling and reconstruction, most notably after the Second World War, and little remains of the original structure as designed by John Nash.
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Sikandar Jah shifted his residence to the Khilwat complex from the Purani Haveli in 1803 and was responsible for the first major constructions. The Gagan Mahal, Bijapur The plan of the Durbar Hall is in traditional Moghul style. Subsequent remodelling, at a time when European architecture was gaining acceptance, resulted in a unique and harmonious mix of diverse architectural styles. European architectural influences, although dominant, blend smoothly with the vernacular, to create one of the best examples of Inde European architectural synthesis.
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Volkmar Machado was educated in Rome. On his return to Portugal, he attempted to create the 'Nude Academy'. He painted panels and ceilings in churches, palaces, noble houses, and public buildings. He is the author of the project of the Oporto Relationship Chain and also produced some paintings in the remodelling of Palácio Nacional de Mafra, Palacio do Grilo, and Palácio Nacional da Ajuda, namely his exquisite frescos on the ceilings regularly exhibiting his tromp l'oeil technique in framings and other archtechtonic elements.
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During 2015 a series of improvement works were conducted and completed on the line. These included remodelling stations, new signaling and other infrastructure improvements such as replacing track and third rail segments, as well as the refurbishing of workshops. The works, which also included the installation of a communications-based train control system, meant that the line was closed on Sundays from February to June of that year on its electrified segment, with replacement bus services operating during that time.
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There are square headed windows on the ground floor, and arched windows above. The house is topped by a low pitched slate roof to give a castle-like feel on approach, behind parapets with balustrades and urn finials. There is also a tall belvedere tower rising at the rear. Remodelling the gardens, behind the house sat a kitchen garden with pergola and associated small orchard, with access to glasshouses, stables and coachhouse beyond (now converted to council offices and storage).
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O'Connell Street, William Street, Bedford Row and Thomas Street) are also retail streets within the city. The city centre saw some works on remodelling in the early 21st century, with pedestrianisation works on Bedford Row, Thomas Street and parts of Catherine Street, as well as widening footpaths on William Street. These works have sought to address a reduction of footfall in the city centre (in turn influencing the closure of many city centre retail businesses) which occurred from the recession of 2008 onwards.
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The small semicircle in front of the building was dedicated at some point during remodelling, and is known as "Canal Square Plaza". Being the only building on the semicircle, the building's address is therefore "1 Canal Square Plaza". However, because AT&T;, the local phone company, has a computer system that does not recognize that address, they cite the building's address as "80 West Center Street" (the old address). Every other service, including the US Post Office, recognizes the Canal Square Plaza address.
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After World War Two a shortage of building materials further reduced the number of large luxury houses. Isolated examples included Logan House, designed by David Style in the 1950s. In the 1960s there was Basil Hughes's design at Snaigow for Earl Cadogan and the remodelling of Gask House by Claude Phillimore. This period also saw considerable restoration of existing houses. During the First World War the government became increasingly aware of Scotland's housing problems, particularly after the Glasgow rent strike of 1915.
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Between 1796-1798 he was the High Sheriff for Denbighshire. George Herbert Kitchin (1870-1951) Between 1907 -1912 George Herbert Kitchin was the architect responsible for remodelling the Hall into a Jacobean style and laid out the formal gardens. Amongst other places, he was the architect for developments at Lygrove House, also known as Lyegrove House, Sodbury, and Compton End, Winchester. Lord Wavertree (Colonel Hall Walker) In 1917, Colonel Hall Walker (later Lord Wavertree), became the owner of the hall.
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Substantial interior remodelling of the main building, discussed since 1906, was finally carried out in 1924 and a new manual training building near the southern building was also erected. Secondary education was available at Crown Street from 1881 to 1960. The school was made a Superior Public School from 1881, and from 1913 to 1947 the school had a boys commercial secondary department and a girls domestic science department form 1913 to 1928. From 1929 to 1960 a girls intermediate high school operated.
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At this time, during the 9th century AD, a three-chambered building with a perishable roof was built upon the upper platform of the structure; the chambers were linked by doorways. The only access to the building was via a narrow, sunken stairway built directly over the earthquake fissure. In its final form Structure 218 stood high, with four stepped platforms supporting the superstructure. The final remodelling of the building resulted in the blocking of the top of the stairway with a wall.
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Jagd- und Lustschloss Wabern The local stately home, Landgrave Karl von Hesse's Jagd- und Lustschloss Wabern (roughly "Wabern Hunting and Delight Palace"), was built in 1701, mainly so that the Landgrave could practise falconry in the nearby Reiherwald (forest). In 1770 some remodelling work was done under the well known Baroque architect Simon Louis du Ry. The Schloss nowadays houses a youth centre. The Evangelical Church was likewise built in the 18th century. It has a Rococo organ worth seeing.
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In fact, the remnants encountered confirm the existence of three periods of construction, starting with the first, which corresponds to the pre-thermae period of Julius Caesar and Claudius. The second cycle occurred during the reigns of Flavius and Anthony, represented by the presence of the public baths, which used the pre-existing structure. Finally, the third phase was initially marked by the remodelling of the building, with its courtyard dramatically reduced. By the 5th century, the building and thermal baths were abandoned.
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Detail of the water channels supporting the baths The plan of the building, located on one of the higher hilltops in the municipality of Braga, has not still be completely uncovered. The complex is of a reasonably large dimension, constructed in the second half of the 1st century, which functioned until the 5th century. Its initial layout included two hot areas and, likely, two areas for autonomous services. These spaces were considerably restricted during the Dicoletian remodelling between the 3rd and 4th centuries.
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Another pupil was John Douglas (1830–1911), who created a successful practice in Chester. Sharpe's architectural works were not limited to churches, nor was his practice confined to architecture. His most important architectural work in the domestic field was his remodelling of Capernwray Hall (1844–48), and in Knutsford he designed a house for the governor of the gaol (1844). In 1838 he was appointed as architect to what was then called the County Lunatic Asylum (later Lancaster Moor Hospital).
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Cherry and Pevsner 1998, p. 11 Henry Hare, 2nd Baron Coleraine (1635–1708) oversaw a substantial remodelling of the house in 1684, and much of the existing south facade dates from that time. The end bays were heightened, and the central porch was rebuilt with stone quoins and pilasters, a balustraded top and a small tower and cupola. A plan from 1684 shows the hall in the house's centre, with service rooms to the west and the main parlour to the east.
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Immediately after his purchase of Trysull Manor House in 1894, Howard Mander commenced its remodelling, transforming it into an exemplar for the Arts and Crafts movement. By 1900, or soon after, he had endowed the village with an institute (now The Thatchers) complete with a billiards room and library. It was lost to the people of the village when the deed of gift was lost or misplaced. He also built neighbouring housing along Trysull Holloway and the fine Manor Farm.
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AAA ATPases assemble into oligomeric assemblies (often homo-hexamers) that form a ring-shaped structure with a central pore. These proteins produce a molecular motor that couples ATP binding and hydrolysis to changes in conformational states that can be propagated through the assembly in order to act upon a target substrate, either translocating or remodelling the substrate. The central pore may be involved in substrate processing. In the hexameric configuration, the ATP-binding site is positioned at the interface between the subunits.
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Navajo Preparatory School is a college preparatory school located in Farmington, New Mexico. The school is fully sanctioned by the Navajo Nation since 1991 when the previous Navajo Academy closed due to lack of funding. The campus is currently undergoing a remodelling project for the past few years that includes new dormitories, classrooms, and an athletic sports complex. The school colors are black, turquoise, yellow, and white which represent the four seasons in Navajo Culture and the mascot is the eagle.
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From 1568 to 1823 the old castle became the head office of the Amt of Hardegsen, headed by a Drost or Amtmann. From 1725 to 1780 major remodelling work was carried out on the castle in order to turn it into domestic buildings for the future estate (Domäne). Of the old castle, only the Muthaus, the Hagenhaus and parts of the castle wall remain. In 1972 the estate and castle site were sold to the town of Hardegsen, who then rented it out.
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The church combines the Decorated and Early English Gothic styles and is built entirely of stone, mostly rubble laid out in courses. Teulon's typical style was "vigorous and idiosyncratic Gothic", and he had a "highly individual command" of that architectural movement. Inside, the roof of the chancel is intricately carved (especially on its corbels), and similar work above the organ chamber and chancel arch was added during the late 19th- century remodelling. All of the carvings were by Thomas Earp.
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A cancer-associated fibroblast (CAF) (also known as tumour-associated fibroblast; carcinogenic- associated fibroblast; activated fibroblast) is a cell type within the tumor microenvironment that promotes tumorigenic features by initiating the remodelling of the extracellular matrix or by secreting cytokines. CAFs are a complex and abundant cell type within the tumour microenvironment; the number cannot decrease, as they are unable to undergo apoptosis. CAFs have been found to be abundant in a tumour stroma. Myofibroblasts and fibroblasts make up CAFs.
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Charged multivesicular body protein 2b is a protein that in humans is encoded by the CHMP2B gene. It forms part of one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane remodelling. CHMP2B forms long chains that spiral around the neck of a budding vesicle. Along with the other components of ESCRT-III, CHMP2B constricts the neck of the vesicle just before it is cleaved away from the membrane.
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When actors refused to participate in the play, the National Assembly and other political organizations intervened, defying the Chapelier law that outlawed government intervention in theatre.Freidland (2002, 263). Critics of the theatre argued that the divide between spectators and performers not only reflected, but encouraged the separation between citizens and government. The remodelling of the Théâtre Feydeau in 1789, for example, removed audience boxes on-stage so that the audience was more confined to an area separate from the stage.
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During mammalian heart induction, a mammalian homologue, Cer1, is associated with the coordinated suppression of the TGFbeta superfamily members Nodal and BMP. This induces Brahma-associated factor 60c (Baf60c), one of three Baf60 variants (a, b, and c) that are mutually exclusively assembled into the SWI/SNF chromatin remodelling complex. Blocking Nodal and BMP also induces lineage-specific transcription factors Gata4 and Tbx5, which interact with Baf60c. Collectively, these proteins redirect SWI/SNF to activate the cardiac program of gene expression.
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On 23 June 1960, the Lyric theatre reopened as the Forum Cinema, with a reduced seating capacity, opening with the film "Porgy and Bess". The cinema underwent extensive remodelling including the closure of its gallery to accommodate the screening of this and other 70mm films. The Forum Theatre was the default epic house for Samuel Bronston's film presenting films such as 55 Days At Peking. The Forum Cinema presented Earthquake in Sensurround showcasing it in 70mm on 20 December 1974.
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Originally, the park had a mascot called Napy, who appeared on the park tickets. He was a bear characterized and dressed in a jacket and beret with a white handkerchief around his neck. After the remodelling in 1998, Napy was replaced by Trasto, an orange alien similar to a bear with a T inside a circle on its stomach. Trasto was used in promotions and appeared on a TV program called CyberClub, but was phased out by 2007 and not replaced.
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Based on studies using mouse models, both tissue resident Natural Killer (NK) cells and cNK cells are thought to contribute to the uNK cell population during pregnancy. The origin of uNK cells has been suggested to occur in two phases dependent on the stage of uterine tissue remodelling. At the onset of decidualisation, local proliferation of tissue resident NK cells occurs with little involvement from circulating NK cells. During the formation of the placenta (placentation), circulating NK cells are recruited.
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The placement of a repressive mark on lysine 27 requires the recruitment of chromatin regulators by transcription factors. These modifiers are either histone modification complexes which covalently modify the histones to move around the nucleosomes and open the chromatin, or chromatin remodelling complexes which involve movement of the nucleosomes without directly modifying them. These histone marks can serve as docking sites of other co-activators as seen with H3K27me3. This occurs through polycomb mediated gene silencing via histone methylation and chromodomain interactions.
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"Carte, Richard D'Oyly (1844–1901), theatre impresario", Oxford Dictionary of National Biography, Oxford University Press. Retrieved 12 May 2020 Having failed to commission an opera to replace it, Carte eventually sold the theatre, at a loss, to a company formed by Harris to run it as a music hall. It re-opened in December 1892, after some remodelling, as The Palace Theatre of Varieties. After running it for a year, Harris appointed the veteran Charles Morton – "the father of the halls"Trussler, p.
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Roberts had originally been a ship's carpenter, but subsequently took over his father's joinery business, studied art and geometry with John Cambrian Rowland, and trained himself to become an architect.Jones, Anthony (1996) Welsh Chapels, NMW, p.87 He went on to design a large number of chapels, particularly in North Wales, and other public buildings. Roberts' surviving work includes Capel Moreia, Llangefni; remodelling of the now-listed Plough Lane Chapel, Brecon and the Rundbogenstil-inspired facade of Capel Bach, Rhos.
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5 The occupation is constantly changing and evolving with the rest of the education workforce in the country. Teaching assistants are increasingly being given more and more responsibility within schools, and it remains to be seen how this "remodelling of the workforce" will alter the occupation. Some additional responsibilities may include supporting with behaviour intervention, running extracurricular activities, lunchtime supervision, and covering teaching staff in their absence. In the EYFS, TA's are sometimes included in adult to child ratios as per government guidelines.
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The remodelling of the State Theatre left it structurally intact but altered its appearance, "dispensing with the arches and pediments and imposing a simple restrained facade". The alterations included the entrance to the picture garden, and made provision for a grocery store on the corner, a millinery shop, and refreshments in the cinema vestibule. Leighton's Art Deco design introduced the Mayan flower to the Theatre. The Art Deco theme runs from the Main Auditorium through the external facades to Beaufort and Walcott Streets.
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The building of the Món Casteller. The Human Tower Museum of Catalonia is one of the actions promoted by Valls City Hall in order to regenerate the city's Old Town. Following the example set by other European cities, the aim is to carry out urban remodelling by creating new places and the enhancement of the urban fabric. Likewise, there will be the installation of new civic and cultural facilities in newly built buildings or reforms will be carried out on existing properties.
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The yellow brick was used but Gutch changed the style to Gothic. Within 40 years the congregation had outgrown its church building, and an enlarged church was required. The noted Gothic Revival architect G.E. Street planned extensive rebuilding, which involved retaining part of Goldicutt & Gutch's structure and remodelling the church in a 14th-century Gothic style. Unusually, Street reversed the traditional orientation of the church so that the chancel faced west rather than east, as is traditional in church architecture.
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'Milton school alterations', Telegraph, 25 January 1935, p.6DPW Plan 202-18-1/1, "Milton State School Brisbane Site Plan" July 1935 (plan shows the location of previous school buildings under the new brick school's footprint) Approval for remodelling Block B for vocational training, at a cost of £913, was given in August 1936.'£9152 approved for hospital at Cracow', Telegraph, 20 August 1936, p.2 Students from Sherwood State School were travelling to Milton for vocational training once a week, prior to 1951.
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Ross Priory is an early 19th-century country house located west of Gartocharn, West Dunbartonshire, on the south shore of Loch Lomond, Scotland. From the 14th century the estate, known as The Ross, was owned by a branch of the Buchanan family of Buchanan Castle, who built a house here in 1695. The present house is the result of remodelling by James Gillespie Graham and was complete in 1816. The term "priory" does not imply ecclesiastical provenance, but is simply a 19th-century romantic affectation.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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Victoria Square, where The River artwork and water feature is located, was once one of the busiest interchanges in Birmingham. By the mid-1900s, plans were drawn up for the remodelling of Victoria Square in a bid to open up Colmore Row to more cars, but those plans were subsequently quashed. By the 1990s, a completely different set of plans were put in place. An international design competition was held for a central water feature in the square, which was won by Dhruva Mistry.
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Hence, the reason why this method is considered the gold-standard technique for measuring bone remodelling. Patients undergo double tetracycline labelling, and then samples of bone are collected using trephine under local anesthetic from the iliac crest as it is the only readily accessible site for bone biopsy. This technique is subject to large measurement errors; it is complex and costly to perform and is invasive, meaning that it is painful to the patients. For these reasons, a bone biopsy is not readily acceptable to patients.
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In 1011, Sophia was also granted Essen Abbey on the death of her cousin Mathilde. The succession had initially been reserved for her younger sister Matilda, who nevertheless had married Count Palatine Ezzo of Lotharingia instead. According to the local historian Georg Humann (1847–1932), Essen was always secondary for Sophia, and the importance of the abbey declined somewhat under her rule. The rebuilding of Essen Minster was delayed, though recent research suggests that it was Sophia who initiated the remodelling of the Enamel Cross.
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Standing slightly forward of Royal Crescent immediately to the east, the building now known as Royal Crescent Mansions was originally built as a two-storey house in the early 19th century. Former Foreign Secretary and Prime Minister George Canning once lived there; this is commemorated by a heritage plaque designed by Eric Gill in the 1920s. Extension to five storeys and conversion into a hotel began in 1848, and it opened in its new form in 1857. Some remodelling took place later in the 19th century.
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Major Brazilian airlines handled by Congonhas Airport and Guarulhos Airport include TAM Airlines, Gol Transportes Aéreos, and Azul Brazilian Airlines. Campo de Marte airport handles some private and small- sized airplanes. In 2006, about 34.3 million people used the city's airports (mainly from Congonhas and Guarulhos International Airport, the only two operating commercial flights). Infraero, Brazil's main aviation authority, estimates that with the remodelling of Guarulhos Airport, São Paulo's airports will be able to handle about 45 million passengers a year within the next five years.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The posttranslational modification of histone tails by either histone-modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to the complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The centre has an attic as its upper storey, topped by a blocking course with scrolled supports at each end. A design with a pediment was prepared for this front, but is thought never to have been built. Though the only decoration is the rustication on the Doric temple's pilasters, a remarkably rich effect is achieved. The northeast and northwest facades of Vanbrugh's original design were entirely undecorated, and a consequent lack of popular appeal may be the reason why they were largely destroyed in later remodelling.
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All CAPs appear to contain a C-terminal actin-binding domain that regulates actin remodelling in response to cellular signals and is required for normal cellular morphology, cell division, growth and locomotion in eukaryotes. CAP directly regulates actin filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localisation and the establishment of cell polarity. Actin exists both as globular (G) (monomeric) actin subunits and assembled into filamentous (F) actin. In cells, actin cycles between these two forms.
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Elina Mottram also worked as an architect in Longreach between 1926-1928 and Rockhampton from 1928-1929. Masonic Temple (1930) Longreach, QLD In Longreach, she designed civic public buildings that include the Masonic Temple, Longreach Motors and the office of Winchcombe Carson Ltd. Evidence of her work also include the remodelling of the Australian Workers' Union building and the School of Arts. Her architecture career was stalled during the 1930s depression shortly after Mottram registered as an architect with the Royal Australian Institute of Architects in 1930.
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An increase in arterial stiffness also increases the load on the heart, since it has to perform more work to maintain the stroke volume. Over time, this increased workload causes left ventricular hypertrophy and left ventricular remodelling, which can lead to heart failure. The increased workload may also be associated with a higher heart rate, a proportionately longer duration of systole and a comparative reduction of duration of diastole. This decreases the amount of time available for perfusion of cardiac tissue, which largely occurs in diastole.
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The Harse Chhina Mogha Morcha was an agrarian revolt in Punjab, that took place 1946–1947. The campaign was launched in 1946, under the leadership of the Communist Party. The movement had been launched in response to a decision from the Punjab Government to decrease the supply of water irrigation to farmers, by remodelling the moghas (canal outlets). The campaign was headed by Comrade Achhar Singh Chhina, Sohan Singh Josh, Mohan Singh Batth, Baba Karam Singh Cheema, Jagbir Singh Chhina, and Gurdial Singh Dhillon.
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Construction in stone would have been a costly and time-consuming exercise, taking around five years and costing about £1,000. The medieval hall stood south-west of the keep and was dismantled in 1796 during the remodelling of the castle. The late-18th- to early-19th-century Shire Hall next to the keep is a large ten-side room. In the south-west corner of the castle is a cylindrical tower named Adrian's Tower from the popular legend that it was built by the Roman Emperor Hadrian.
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The church did not have a baptismal font until 1664 when it was provided by visiting parish priest António Pires de Serpa. On 4 October 1945, the church was damaged by an ocean swell (some say tsunami). Major damage also occurred on 1 January 1980 as a result of the Azores earthquake which affected many of the islands of the Central Group, destroying much of Angra do Heroísmo. Plans for remodelling were prepared in the late 1980s and the church was reopened in 1991.
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In 2003, she was responsible for setting up the Leadership Strategy of the London Challenge and directed the Financial Management in Schools Project. In September 2002, Pat Collarbone was seconded from the Institute of Education as Director of Leadership Development Programmes at NCSL, a post she held until December 2005. During her tenure she oversaw the development of a number of leadership programmes. She was a Director of NCSL and the Director of the National Remodelling Team (NRT) within NCSL, and later, TDA until August 2006.
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The front portal is one of the oldest and most richly ornamented in the country. It takes the form of three winged dragons, one on each side of the arch and pilasters of the entrance and one above, all elaborately intertwined in a tendril and leaf pattern. The remodelling and expansion of original building into a cruciform church is believed to have been completed in 1699, although some sources claim 1738. Restoration work was done during 1902 under direction of architect Carl Berner (1877–1943).
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Brown (2006), 36 One drawing, for example, shows the remodelling of the Irnham parish church, emphasizing how he was preoccupied with his activities in preparation for his death. The miniature of Sir Geoffrey Luttrell mounted on the horse wearing full armour beside his wife and daughter-in-law is a very powerful image in the Luttrell Psalter. It suggests that he wanted to be remembered for his youth and for his time spent in the military. The image also shows the Luttrell's family heraldry.
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Once out of prison, Echols had few job skills and did not apply for a driver’s license because he worried he would be stopped by police and sent back to prison. In 2000, Echols was arrested in Memphis for being outside of his parole. Although he had been allowed to move to Mississippi to set up a home remodelling business, he had not reported to his parole officer for two years and an arrest warrant was issued. Echols claims that he thought his parole had ended.
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310Giulia Foscari, Elements of Venice, 2014, , p. 150Egle Trincanato, Umberto Franzoi, Venise au fil du temps, Éditions Cuénot:1971, index The façade of the church San Moisè has been called "the busiest façade in town" and contrasts with the travertine cladding and light-colored marble columns of the Bauer, "brutally modernist in its plainness";Margaret Plant, Venice: Fragile City, 1797-1997, 2002, , p. 353 Joseph Brodsky described the juxtaposition as "Albert Speer having a pizza capricciosa". The hotel underwent a major remodelling in 1999, under Bortolotto Possati.
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The former Queensland National Bank is a simple single-storey rendered brick building with a corrugated galvanised iron roof behind a raised parapet. The symmetrical main facade facing Brisbane St has a central doorway with a modern glass door, surmounted by a pediment and flanked by a pair of rectangular openings which still contain early double- hung timber windows. The facade is decorated with simple pilasters and imitation block quoins. Beneath each window is a decorative motif consistent with the 1930s date of the building's remodelling.
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The ecclesiastical focus of Balmaghie was Balmaghie Kirk, until its closure in 2015. Plans to sell the church for housing conversion were withdrawn following widespread protests and a petition and it has now been taken over by the Balmaghie Sacred Landscape Trust and the building is now in community use. The church was built in 1794 and set on a small hillock in Balmaghie overlooking Loch Ken and opposite Crossmichael Kirk on the far bank. Remodelling was carried out by Peddie and Kinnear in 1891-94.
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When insufficient oxygen is available, vascular remodelling occurs and poorly remodelled blood vessels leak, causing edema. The conversion of all-trans- retinol to 11-cis-retinal is a very oxygen intensive process. By blocking the isomerisation of retinol, emixustat hydrochloride may decrease the oxygen demand of the retina and therefore liberate large amounts of oxygen for other processes. In a completed Phase 1a study, the drug was "well tolerated" by male and female human participants, and demonstrated dose-dependent modulation of electroretinogram (ERG) signals.
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Linz's original central station building. The first Linz central station building was completed in 1858, to coincide with the arrival of the Empress Elisabeth Railway company's Western Railway from Vienna. The station was rebuilt from 1936 by the Nazi's - being the closest city to Adolf Hitler's birthplace - in a severe modernist style characterized by a reinforced concrete frame, high ceilings, and elongated windows. But by the time of its completion, Linz had already been designated one of five Fuhrer Cities, where complete remodelling would take place.
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Sword Pommel from the Bedale Hoard Before the Harrying of the North Bedale was held by Torpin (Thorfinn), a patronym retained by the infamous Dick Turpin. The parish church also dates from this time (as evidenced by its crypt), before significant remodelling. The original 9th century church escaped destruction in the Harrying of the North and was recorded in the Domesday Book. The recent discovery of the Bedale Hoard provides further evidence of high-status Anglo-Saxon and Viking Age activity in the area.
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Planning for Arrowe Park Hospital began in the 1960s, although building did not start until the late 1970s. The facility was built to replace Birkenhead General Hospital in Birkenhead, Highfield Maternity Hospital in Wallasey, Leasowe Hospital in Leasowe, St Catherine's Hospital in Birkenhead and Victoria Central Hospital in Wallasey. The hospital was officially opened by the Queen on 4 May 1982. In March 2011, following remodelling work at a cost of £11.5 million, the maternity and gynaecology unit was renamed Wirral Women and Children's Hospital.
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When the Christchurch Central Development Unit released plans in 2014 for a NZ$7–8 million remodelling as part of the Avon River precinct upgrade, a huge public outcry was the result. Government's announcement was not consultation, but was issued for information, and the resulting calls for a consultation exercise were initially denied. In February 2015, the project was put on hold and a public consultation period started. In July 2015, draft plans were released for some restoration work that will see Victoria Square largely unchanged.
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The issue with the lack of wildlife now is that as the beck was culverted, it runs very fast through concrete and stone channels and as such the water flow is too fast to sustain much of the wildlife that would normally inhabit a beck of this size. The Friends of Bradford's Becks are wanting to rectify this by remodelling some of the lower reaches of the beck where it is exposed to daylight and slowing the water flow down by adding in bends.
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Prince Henry's Battery was an artillery battery built in Gibraltar during the Anglo-Spanish War of 1762–63, adjoining the Prince of Wales Lines. They mounted three 32-pdr guns with two more 18-pdrs, six 12-pdrs and three 4-pdrs on the Lines. After 1841, the battery was rebuilt as a retired battery as part of a mid-19th century remodelling of Gibraltar's southern defences. They were eventually built over in 1859–60 when the Prince of Wales Batteries were constructed on the same site.
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From the end of World War I the building was being leased as shops and offices. Major remodelling took place to accommodate the change in use. Occupants of the building from this time included American Bag Stores Ltd, NSW Blinded Soldiers Tea Co. Ltd, Thompson Silk Stores, Californian Chocolate Shop, and Sellor's Silk Store. In the 1970s the building was occupied by the Grahame Book Company, a well known bookshop which in the 1950s was regarded in a class with Dymocks and Angus & Robertson.
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Between the two platforms tracks there are two further lines, used by fast trains not booked to call here. Prior to the remodelling of the station, the two lines crossed at a flat crossing with a curve connecting the northern and eastern tracks, allowing trains on the Sheffield-Gainsborough line to call at the station. There were two northbound platforms - platform 2 (now closed) was on the eastern side of an island platform and platform 3 on the opposite side (still in use, now renumbered 2).
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Approximately two-thirds of human serpins perform extracellular roles, inhibiting proteases in the bloodstream in order to modulate their activities. For example, extracellular serpins regulate the proteolytic cascades central to blood clotting (antithrombin), the inflammatory and immune responses (antitrypsin, antichymotrypsin, and C1-inhibitor) and tissue remodelling (PAI-1). By inhibiting signalling cascade proteases, they can also affect development. The table of human serpins (below) provides examples of the range of functions performed by human serpin, as well as some of the diseases that result from serpin deficiency.
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Other orders sprang up which followed the Rule of St. Augustine and the canonical life. As canons regular became separated into different congregations they took their names from the locality in which they lived, or from the distinctive habit they wore, or from the one who led the way in remodelling their lives. Hence we have the White Canons of Prémontré; the White Canons of Saint John Lateran; the Black Canons of St. Augustine; the Canons of St. Victor at Paris and also at Marseilles.
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119 The 8th century is normal used as a reference, suggesting a construction based on the reuse of existing Roman-era elements. The actual configuration of the temple is difficult to catalog. On one hand, the constructors reused the capitals, presupposing a public construction that occurred in the High Middle Ages. On the other hand, successive remodelling, painting and lack of prior archaeological excavations has made rigorous analysis impossible; this lack of information has contributed to the difficulty in dating and contextualizing the style of architecture.
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Excessive collagen degradation may be associated with cancer metastasis, skin ageing, arthritis, and osteoporosis. CHPs can target tissues undergoing remodelling based on their ability to bind to degraded and unfolded collagen strands through triple helix formation. As a targeting moiety, CHPs offer great potential in histopathology, diagnostics, and drug delivery for a wide range of diseases. Most methods for the evaluation of collagen denaturation in disease states are indirect, such as detecting matrix metalloproteinase (MMP) activity or quantifying collagen peptide fragments in urine, serum, or synovial fluid.
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He said: "various evidences are at hand of the transformation or remodelling of individual chambers," such as walls of gypsum blocks. In short, Evans had discovered archaeologically a "first palace" under the Mycenaean, which was now the "second palace." Deep test pits to the virgin soil under the hill had revealed many meters of Neolithic habitation; i.e., before the "Palace Period,", the Neolithic people had an ancient city at that location (modern studies have shown it to have been the most ancient city of the Mediterranean).
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The previous Marshgate Junction allowed for a maximum speed of 60 mph on the Doncaster - York main lines with diverging speeds of 25 mph on the main lines to and from Leeds and Thorne. Other speeds were 15 mph. The remodelling of the layout in association with other improvements in the Doncaster station area allowed speeds of 105 mph through the Doncaster section of the East Coast Main Line route. The divergence to and from the Leeds Line allowed a maximum speed of 70 mph.
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The Anton Karg Haus has a long tradition. In 1882 the borough of Kufstein lent the Kufstein Branch an alpine hut which, after remodelling, was opened as the Hinterbärenbad Hut on 25 July 1883. After a further expansion in 1884 the house, together with a second, newly built wooden building, was transferred to the full ownership of the Kufstein Branch. After the construction of a veranda and the conversion of the second building into sleeping accommodation the Hinterbärenbad Refuge House was open for guests from 1887.
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Around 1546, Spytek Jordan ordered the remodelling of the Gothic keep, turning it into a Renaissance residence. After the marriages of his two daughters, Melsztyn became the property of the Tarło family, and in 1744, it came into the hands of the Lanckoroński family. Ruins of the Melsztyn Castle Melsztyn Castle was destroyed by the Russians in 1771, during the Bar Confederation, and has been a ruin since. In 1789–1796, parts of the complex were pulled down, for building material for a church at Domosławice.
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Granzyme B can also mediate the death of cells after spinal cord injury and is found at elevated levels in rheumatoid arthritis. COPD (Chronic Obstructive Pulmonary Disease) has been attributed to granzyme B secreted from NK and T cells causing the apoptosis of bronchial epithelial cells. Matrix destabilisation and remodelling by granzyme B is also linked to asthma pathogenesis. Granzyme B can kill melanocytes causing the skin condition vitiligo and granzyme B overexpression is found in contact dermatitis, lichen sclerosus and lichen planus cases.
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At the end of the gallery is a closet with a domed circle supported by eight columns; halfway through the columns is a doorway imitating a niche. In the 1820s the north range of the house that was not completed by Adam was redesigned by the 3rd Duke. At this time the house was also refaced in Bath stone and the porch rebuilt. This remodelling is thought to have been done by the architect Thomas Cady, who had worked on other estates belonging to the Percy family.
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These changes were primarily due to the increase use of the palace. In 1828 Miguel of Portugal was acclaimed by the Portuguese Estates General in the Cortes Hall (today the Dining Room). Miguel also inhabited the palace for six months as the royal residence, the Palace of Necessidades, underwent remodelling. The move of the Royal Court to Queluz in 1829, and the death of the architect Rosa, resulted in a slowing of the project, and the affected the north wing which fell into ruin.
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The domestic structures of Freiha appear typical of the Persian Gulf region and the time period. They consist of small stone built rooms, frequently with small open courtyards attached to them. Where excavations have been carried out, these structures appear to undergo constant remodelling throughout their lifespan, often with small rooms and sub divisions being added. Finds evidence in the form of stone fishing weights, large amounts of fish bones and the presence of extensive tidal fish traps suggests a primarily marine based economy.
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The Abbey community is under the charge of an Abbess who is elected by the members and holds the position for life, since 1624 twenty-two Lady Abbesses have held the post, those in recent history are listed below: 17\. Dame Juliana Forster (1837-1869) - Bought the community to Oulton and oversaw the building of the church 18\. Dame Mary Catherine Beech (1869-1899) - Oversaw the extensions and remodelling of Oulton House 19\. Dame Laurentia Ward (1900-1921) - The daughter of William George Ward 20\.
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The extended EGL-27 and MTA1 homology domain, or EELM2 domain, is a protein domain that occurs in proteins from apicomplexan parasites. Part of the EELM2 domain is homologous to the ELM2 domain, but is 'extended' in that its boundaries (the region of conservation) are longer than in the ELM2 domain. Currently (as of 2012), little is known about the function of this domain. However, some proteins that contain an EELM2 domain also contain a PHD finger domain, which is thought to be involved in chromatin remodelling.
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Prior to migration, during a process known as epithelial-mesenchymal transition, there is a loss of cell contact, remodelling of the cytoskeleton and increased motility and interaction with extracellular components in the matrix. An important step in this process is the suppression of adhesion protein E-cadherin present on epithelial cells to initiate the migration process. This suppression mechanism occurs via the growth factor BMP signalling to turn on a transcriptional repressor Smad-interacting protein 1 (Sip1) and marks the beginning of the epithelial-mesenchymal transition.
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This later undergoes remodelling to form the left-sided aortic pattern present in adult hearts. The group of cells found in the third aortic arch gives rise to common carotid arteries. Cells found in the fourth aortic arch differentiates to form the distal aortic arch and right subclavian artery, whilst cells in the sixth aortic arch develops into the pulmonary arteries. Cardiac neural crest cells express Hox genes that supports the development of arteries 3, 4 and 6 and the simultaneous regression of arteries 1 and 2.
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Brick schools were all individually designed and were built in areas where a large population justified their construction. Brick schools were not commonplace which makes the Ipswich West State School buildings a good example of the type of school buildings erected in an established urban area during the period. In 1934 the Boys' and Girls' Schools again became coeducational, occupying only the brick buildings, with C.W. Munro as the Headmaster. At this time pupils numbered 232 and remodelling of the school was undertaken at a cost of .
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According to an inscription above the doorway of the south aisle, remodelling and expansion were undertaken in 1497 that led to the church being transformed into a three- aisled Gothic hall church with an irregular transept and an eight-sided choir area. Since the Reformation's introduction in Hesse in 1526, Evangelical services have been held there. The 36-m-high tower, the town's landmark, is built as a mighty military tower. The tower's roof is ringed with a walk with a tracery gallery from about 1500.
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Nebe and Widmann concluded that killing with explosives was impractical, while gassing "held promise", as vehicles were readily available and could be used as needed. After these experimental killings, Nebe thought of remodelling a vehicle with a hermetically sealed cabin for killing. The carbon monoxide from the vehicle's exhaust would be channelled into the sealed cabin in which the victims stood. He discussed the technical aspects of the idea with a specialist from Kripo's Technology Institute and together they brought the proposal before Heydrich, who approved it.
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Beckett's wealth and reputation gave him considerable status in Leeds, and in 1832 he bought an estate called New Grange in Headingley and renamed it Kirkstall Grange. The estate comprised large house on a hill and an extensive private park. He carried out extensive improvements and remodelling to the house and park, hoping at one point to have Queen Victoria as house guest when she visited Leeds in 1858. The park became Beckett Park, a public park, and the house a building within Leeds Beckett University.
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The cupola from one of the Wren pavilions was removed and mounted on the stable block designed by James Gibbs. The cottage still stands today and is partially visible from London Road, beyond a tall brick wall from the same period. Other alterations to the house included the remodelling of the entrance (east) front where the portico, which had originally faced onto the former Aylesbury to Berkhamsted road through the park, was demolished and a new porte-cochère was built on the north front.
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An alternative method, using limb length and body mass, found Apatosaurus grew per year, and reached its full mass before it was about 70years old. These estimates have been called unreliable because the calculation methods are not sound; old growth lines would have been obliterated by bone remodelling. One of the first identified growth factors of Apatosaurus was the number of sacral vertebrae, which increased to five by the time of the creature's maturity. This was first noted in 1903 and again in 1936.
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The changing fashions in the Victorian period led to the church being re-modelled by Edward Haycock Jnr, the grandson of John Hiram Haycock, in 1876. The doorway in the west tower was blocked, stone facing for brick, and Gothic revival windows, except for the circular ones on its second stage. Ashlar quoins all the way up to the steeper-than-traditional pyramid of the remodelling. Ashlar quoins also at the NW, SW, and SE angles of the nave, which is of C18 proportions.
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Besides the new sports arena, the remodelling included the construction of a police station for the city police, a new bus station and a new park, the Parc de l'Estació del Nord. The sports facilities were first used for an Olympic test event in 1991, whilst the bus station was commissioned after the completion of the games. In 2008, works were undertaken at Arc de Triomf station to improve access exchange with the bus station, including the provision of a new entrance facing the Estació del Nord.
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Over 100 years ago, Thoma observed that increases in local blood flow cause widening of the vessel diameter and he even went so far as to postulate that blood flow might be responsible for the growth and development of blood vessels Thoma, R. (1893). Untersuchungen ü ber die Histogenese und Histo- mechanik des 1186 Gefä ßsystems. Stuttgart, Germany: Ferdinand Enke . Subsequently, Chapman in 1918 discovered that removing a chick embryo's heart disrupted the remodelling process, but the initial vessel patterns laid down by vasculogenesis remained undisturbed.
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The remains of the motte, now wooded, with the River Clun in flood around it. Broadward Hall is a Grade II Listed building, largely a 19th-century remodelling of an 18th-century house, with a castellated Gothic appearance.British Listed Buildings Broadward Hall, Clungunford Broadward dates back much earlier however, and was a medieval settlementHistoric Houses Association Broadward Hall with township status within the Clungunford parish.GENUKI The National Gazetteer of Great Britain and Ireland (1868) The hall is a private residence and is not open to visitors.
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According to Hertzen (2002), a common characteristic of asthmatic patients is to have epithelial cells that respond to injury by enhancing the capability of producing proinflammatory and profibrogenic cytokines, instead of repairing the injured epithelial layer. As a result, inflammation and associated healing process leads to scar formation and tissue remodelling, which are symptoms that can be found in almost all asthmatics patients. Thus, asthma is a chronic inflammatory disorder of the airways. Asthma is divided into two subgroups: atopic (extrinsic) and non-atopic (intrinsic).
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A collector since childhood, in 2009 he formed the museum to place his antiquity and classical art collection on public display. The Musée de Mougins was created by remodelling a 600m2 medieval edifice to house his collection. The building itself used to be the village prison in medieval times, it was then turned into a mill before becoming a private residence in the 1950s. The interior was entirely renovated to display the collection while the façade remains in its original style. The museum’s director is Leisa Paoli.
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The mountain-top stadium at Delphi, far above the temples-theater below The stadium is located further up the hill, beyond the via sacra and the theatre. It was originally built in the 5th century BC but was altered in later centuries. The last major remodelling took place in the 2nd century AD under the patronage of Herodes Atticus when the stone seating was built and (arched) entrance. It could seat 6500 spectators and the track was 177 metres long and 25.5 metres wide.
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Colvin 1995, s.v. "Wakefield, William". Minor alterations were made in the 1750s by John Carr, who was engaged in remodelling the interior of the prominent Fairfax seat in York, Fairfax House, in Castlegate.Colvin 1995, s.v. "Carr, John". On the death of Mrs Barnes (Lavinia Fairfax) in 1885, this branch of the family became extinct and the castle, after passing through several hands, was bought by Ampleforth Abbey in 1929. The vendor, however, retained the panelling and glass of the Great Chamber and sold it separately.
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The aortic arches or pharyngeal arch arteries (previously referred to as branchial arches in human embryos) are a series of six paired embryological vascular structures which give rise to the great arteries of the neck and head. They are ventral to the dorsal aorta and arise from the aortic sac. The aortic arches are formed sequentially within the pharyngeal arches and initially appear symmetrical on both sides of the embryo, but then undergo a significant remodelling to form the final asymmetrical structure of the great arteries.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The track engineering works are visible behind the (now abolished) signal box at Huyton, in December 2013. Work is complete to re-instate the four track layout which was originally in place between Huyton and Roby stations until the 1970s. This is part of the Electrification/Northern Hub improvement. It provides passing tracks to allow for slow and fast traffic plus a remodelling of the Huyton Junction turnout towards Prescot in order to avoid substantial interaction with the Liverpool–Manchester line, which was previously the case.
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Prince, p.395, 1810 footnote 5 (1810) The present mansion house is Tudor (16th century) with refurbishment from the late 17th century and further remodelling from about 1800.Listed building text The prefix "Great" dates from the late 17th century and served to distinguish it from the mansion house known as "Little Fulford"later known as Shobrooke Park, which was destroyed by fire in 1947.(Pevsner, p.729) in the parish of Shobrooke, Devon, about 8 miles to the north-east, also owned briefly by Col.
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The current house was remodelled in 1783-1785 in Palladian style by John Soane, who also added stables and lodge. It is, however, possible that the quite conservative interior remodelling work was done by Norwich builder and sculptor John de Carle (1750-1828) and Lord Camelford to Soane's designs: de Carle supplied at least one of the fireplaces. It has been considered a smaller version of Holkham Hall nearby. Soane also added a split cantilevered staircase, and the piano nobile on the first floor.
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Bardon Park ChapelBardon Park Chapel is a 17th-century nonconformist chapel in the southernmost part of the parish, close to the main A511 road (formerly the A50) between M1 Junction 22 and Coalville. The chapel was built in about 1694 and altered in about 1830, 1877 and about 1900. A number of original 17th- century features survive, including the roof trusses and the wooden pulpit, which is octagonal and has fluted Doric pilasters. A wooden screen and doors date from the remodelling of about 1830.
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For example, CNCCs are required for the formation of the aorticopulmonary septum (APS) that directs cardiac outflow into two tracts: the pulmonary trunk and the aorta of the developing heart. This is an example of remodelling which is dependent on signalling back and forth between CNCCs and the cardiogenic mesoderm. If this signalling is disrupted or there are defects in the CNCCS, cardiovascular anomalies may develop. These anomalies include persistent truncus arteriosus (PTA), double outlet right ventricle (DORV), tetralogy of Fallot and DiGeorge syndrome.
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Immediately behind the facade is the Great Hall, , with three galleries. Beyond this are the two courtrooms: Court 1 (now open to the public, with displays of museum artefacts related to crime and policing) for the High Court and Court 2, the magistrates' court. The latter has many original fittings, but the former was enlarged by the county surveyor, Charles Trubshaw, and refitted by local joiner Thomas Bull, in 1854. The 1854 remodelling extended the building over a market for dairy produce, The Butter Market.
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Villani boasts of Florence's pristine architecture in its monasteries and churches, as well as its ornate houses and beautiful palaces.Spilner, 459. His opinion is clear even in the title of the chapter he devotes to this topic, "More on the greatness and status and magnificence of the city of Florence". However, Villani is quick to add that those who spent too much on the lavish excesses of continuous remodelling and refurnishing of homes were sinners and could be "considered crazy because of their extravagant spending".
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A new transport interchange was developed which included a coach station and an underground fast tram line. A new shopping centre (Galeria Krakowska, Kraków Gallery) opened in September 2006. The construction of the Galeria Krakowska and remodelling of the area in front of the main station building means that taxis are no longer able to drive up to the station building, instead they can drive to the parking situated directly above railway tracks and connected by lifts and steps with platforms and underground ticket hall.
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Precise documentation of the remodelling is not extant, but numerous details are typical of the 1860s, and no extant building anywhere in the United States is known to have employed the Italianate style before 1844.Sheridan, Ellen M., and Marlene H. Lentz. '. National Park Service, 1987-12-15, 3. In 1975, Austin's house was listed on the National Register of Historic Places, qualifying for inclusion both because of its historically significant architecture and because of its place as the home of a regionally significant man.
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In later years, a gymnasium/canteen complex was constructed, being partially funded by the former City of Nunawading as well as a football/cricket oval and soccer field. The school changed its name to Vermont Secondary College in 1991. Vermont Secondary College school provides education for years 7-12 in the VCE system. The school has recently undergone significant renovations with 2 of the 3 LTC wings undergoing significant remodelling and partial demolition and a 4th wing consisting of 12 portable class rooms being added.
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The original staging of Cats at the New London Theatre was considered revolutionary and "one of the first truly immersive theatrical experiences". Instead of a conventional proscenium, the theatre was quasi-in-the-round with a central revolving stage. Nunn and Napier had sought to create "an environment rather than a set", and around $900,000 was spent remodelling the New London in preparation for the show. This included mounting sections of the stalls onto the theatre's revolve such that the audience moved along with the stage.
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The post-translational modification of histone tails by either histone modifying complexes or chromatin remodelling complexes are interpreted by the cell and lead to complex, combinatorial transcriptional output. It is thought that a Histone code dictates the expression of genes by a complex interaction between the histones in a particular region. The current understanding and interpretation of histones comes from two large scale projects: ENCODE and the Epigenomic roadmap. The purpose of the epigenomic study was to investigate epigenetic changes across the entire genome.
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The new house incorporated part of the 15th-century castle. In 1796, the 15th Earl of Glencairn Lord Kilmaurs, Chief of Clan Cunningham, died without issue, and Finlaystone passed to a cousin, Robert Graham of Gartmore, whose family took the name Cunninghame Graham. The Cunninghame Grahams sold Finlaystone in 1862 to Sir David Carrick-Buchanan, who in turn sold it in 1882 to George Jardine Kidston. Kidston commissioned the architect John James Burnet to carry out a Scots Baronial style remodelling of the house, completed in 1903.
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Rental notice for Deer Park in1846 Nicholas Fry (1676-1714) built the present houseBridget Cherry, Nikolaus Pevsner, “Devon”, p. 221. Online reference which is possibly a remodelling of an older residence that was on the site.English Heritage Register “The Deer Park Hotel” Online reference He inherited the property in 1707 from his uncle Richard FryThe National Archives; Kew, England; Prerogative Court of Canterbury and Related Probate Jurisdictions: Will Registers; Class: PROB 11; Piece: 500 whose grave is in the churchyard at Buckerell.Find A Grave website.
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Excavation has revealed that a large stone cross, like a market cross, stood just west of the main building. The abbey gatehouse. Though Cleeve was by no means a wealthy house, the monks were able to make significant investment in remodelling their home so as to match the rising living standards of the later mediaeval period. In the fourteenth-century elaborate polychrome tiled floors (an expensive and high status product) were laid throughout the abbey and in the mid-fifteenth century radical works were undertaken.
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Many common building materials used before 1975 contain asbestos, such as some floor tiles, ceiling tiles, shingles, fireproofing, heating systems, pipe wrap, taping muds, mastics, and other insulation materials. Normally, significant releases of asbestos fiber do not occur unless the building materials are disturbed, such as by cutting, sanding, drilling, or building remodelling. Removal of asbestos-containing materials is not always optimal because the fibers can be spread into the air during the removal process. A management program for intact asbestos- containing materials is often recommended instead.
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Many of these adaptions and remodelling continued on until 1790, when José António's son, Manuel José da Matta Sousa Coutinho took up the title of the 11th and last official High Courier. After this, the title was reincorporated by the Crown, and Manuel José received a rent and noble peerage (1st Count of Penafiel), while renting out the estate until 1812. In 1833, he returned from self-imposed exile (owing to the Napoleonic conflicts), where he yielded the residence to shelter the injured from the Liberal Wars.
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The architect Louis Parant was commissioned for the reconstruction, who decided to build an entirely new building with a self-supporting steel structure built inside the shell of the ruins. This new building was modelled after the city hall of the French city of Tours.City of Montreal Web site (in French) Other changes included a remodelling of the Mansard roof into a new Beaux-Arts inspired model, with a copper roof instead of the original slate tiles. The new building opened on February 15, 1926.
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Both designers got along well and set-up a partnership under the name Simpson & Arana with the goal of initiating reconstruction work at a national scale. Thus started an intense relationship that would result in the remodelling of Lasarte (1946), Pedreña (1946), Sant Cugat (1946), Terramar (1947) Málaga (1949) and Pedralbes (1949). The main project of this time was the construction of the first 9 holes of the Real Club de Golf Cerdaña, in Puigcerdá, Javier's first solo design. Simpson's influence over Javier was very relevant.
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He died without issue and bequeathed Kettlethorpe to his half-brother's son, Charles Amcotts, MP of Harrington Hall. He in turn left it to his sister Anna-Maria, who had married Sir Wharton Emerson, who changed his name to Amcotts. After passing by marriage to Sir William Amcotts-Ingilby it was inherited by Weston Cracroft Amcotts, MP, who carried out extensive remodelling of the house in 1863. It then further passed down in the family to Sir Weston Cracroft-Amcotts, who sold it in 1961.
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' ("'Font Santa's Well", also known as ' or 'Information Board, Ajuntament de Campos) is an historic building, housing a rainwater storage well, in the municipality of Campos, Majorca. It was built in 1671–1673, during the restoration of the adjacent Church of , by remodelling the bathing room of a house known as . It used a double filter system and delivered water to external and internal wash basins, as well a drinking troughs for animals. It had a capacity of and was in use until the late nineteenth century.
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The remodelling was done by architects James Pain and his brother George Richard Pain. During the War of Independence (1919–21), Clare County Council held their meetings at Knappogue Castle where they were guarded by the East Clare Flying Column. Michael Brennan, Commander of the East Clare Brigade also used the castle as his headquarters during that time.Framed and Glazed photograph, East Clare Brigade In 1927, Knappogue demesne was purchased by the Irish Land Commission and the castle became the possession of the Quinn family .
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While the new residence in Cuttack was under construction, the Raj Bhavan at Puri underwent remodelling at a cost of Rs. 158,000 to "make it suitable and comfortable for the imperial dignity of His Majesty's representatives in India" with improvements including rewiring, updating of the plumbing system and the creation of a garden. The building remained in use as the summer residence for governors until 1973, then in 1983 part of the grounds were sold off for the construction of a hotel to boost state tourism.
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Saint Philip's and Saint James's Church (Kirche St. Philippus und Jakobus) was built between 1766 and 1769 and cost, according to a surviving request document sent to the then Prince-Archbishop-Elector of Trier, Johann Phillip von Walderdorf, 2,000 Reichsthaler. The first work to strengthen the church's structure was undertaken as early as 1777. Further work needed to be done in 1845, 1861, 1863, 1881 and 1883. Remodelling between 1959 and 1962 fundamentally altered the church, with the chancel and quire being completely changed.
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G Logan and E Clarke, State Education in Queensland: a brief history, a report for the Department of Education, Queensland, 1984, pp.3-5Burmester et al, Queensland Schools A Heritage Conservation Study, p.58. The remodelling of Block B included altering the internal partitions and partially enclosing the verandahs to create woodwork and sheet metalwork rooms and a teachers room on the ground floor, and cookery, dining and dressmaking rooms, a lecture room and a laundry on the first floor. The ground floor of Block B sat lower than the undercroft level of the new brick building, and the only access to the first floor was via an L-shaped staircase on the southwest side.DPW Plan 180-22-8, "Milton State School - remodelling 2 storey building for domestic science & manual training", July 1936. The new school, with a total cost of £30,000, was in use from March 1937, and was officially opened in May by the Minister for Public Instruction, Frank Cooper. By this time 833 students were enrolled. Minister Cooper said that the new school "would stand for the next century or more".
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The interior houses the Benton Fletcher collection of early keyboard instruments, some of which are often played for visitors during operational hours, and collections of paintings (including the collection of Peter Barkworth and loans of Sir William Nicholson paintings), Meissen, English and Chinese porcelain, 17th-century needlework pictures and Georgian furniture. It also has fine portraits of King William IV (when Duke of Clarence) and his mistress Dorothea Jordan, as well as portraits of two of their illegitimate sons, Frederick FitzClarence and Adolphus FitzClarence, and one of William IV's brother George IV. The brick mansion, with 1693 inscribed on its chimney breast which is consistent with the date of its core and most of its walls, has a 300-year-old orchard, where around 30 types of apple trees flourish. Apple day, held in late September every year, gives members of the general public the opportunity to savour some of its rare and delicious apples, along with other goodies like apple-blossom honey. ;19th century remodelling by a Riga merchant PI Fenton, a Riga merchant, bought the house in 1793 and in the 19th century ordered much of the remodelling.
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The façade (completed 1612) is constructed to allow for Papal blessings from the emphatically enriched balcony above the central door. This forward extension of the basilica (which grew from Michelangelo's Greek cross to the present Latin cross) has been criticized because it blocks the view of the dome when seen from the Piazza and often ignores the fact that the approaching avenue is modern. Maderno did not have as much freedom in designing this building as he had for others structures. Most of Maderno's work continued to be the remodelling of existing structures.
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Glenn Maxwell was born in Kew, Victoria, and played his junior cricket for South Belgrave CC. He began his cricket as a pace bowler, before remodelling his run-up and becoming an off spin bowler. Despite that, he also has a deceptively powerful and accurate throw to effect run-outs. Maxwell's teammates and the media gave him the nickname "The Big Show" due to his confidence and his tendency to play extravagant shots, especially a wide array and variations of sweep shots. He however prefers the nickname "Maxi".
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There is evidence that a pub has been on the site since 1533, and that it was named The Ram Inn from at least 1581. The current building is a Grade II listed building, constructed in 1883, with remodelling in the 1930s. It formed part of the brewery complex of the former Young's brewery and although it was historically known as the Ram Inn, in the twentieth century its name was changed to The Brewery Tap. Controversially, the pub closed in 2006 when Young's closed the Ram Brewery.
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Ermine, on a chief azure 5 bezants Sutton Place remained in the Weston family and families related to it by marriage until 1919, although let out for part of the time. The family was recusant from Tudor times, which precluded it from taking an active part in public life. Successive occupants thus lived as retiring country gentlemen of reduced means, which meant that the house escaped remodelling through the ages. A collection of portraits of the Weston, Webbe and Webbe-Weston family was sold at auction on 13 July 2005 by Sotheby's Olympia, London.
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The feature was accused in an anonymous article in People's Daily in May 1951 of spreading feudal ideas. After the article was revealed to be penned by Mao Zedong, the film was banned, a Film Steering Committee was formed to "re- educate" the film industry and within two years, these private studios were all incorporated into the state-run Shanghai Film Studio.Ward, Julian. "The Remodelling of a National Cinema: Chinese Films of the Seventeen Years (1949–66)", in The Chinese Cinema Book, edited by Song Hwee Lim and Julian Ward (2011).
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Henrico County Courthouse Shenadoah Apartments Maury Place Stokes House Carl Ruehrmund (1855–1927) was a German-born architect who worked briefly in Germany and then immigrated to the United States, establishing a successful practice and legacy in Richmond, Virginia. Ruehrmund was born in Berlin, Germany and studied Architecture and Engineering at the Royal Academy in Berlin. He began his career working on German government projects before immigrating to the United States in 1881. Ruehrmund came to Richmond around 1882 to oversee the remodelling of the Central Post Office.
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Wu JI, Lessard J, Crabtree GR. Understanding the words of chromatin regulation. Cell. 136(2): 200-206, 2009. . In 2009 he worked with post doctoral fellow, Andrew Yoo to discover a genetic circuitry controlling the assembly of specialized, brain-specific chromatin regulatory complexes necessary for the development of the mammalian nervous system and demonstrated that recapitulating this circuitry in mammalian cells converts human skin cells to neurons.Yoo AS, Staahl BT, Chen L, Crabtree GR. MicroRNA- mediated switching of chromatin-remodelling complexes in neural development. Nature. 460(7261): 642-646, 2009. .
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This remodelling led to the covering of the oak beams with a curved plaster ceiling, "a most barbarous innovation". The weight of the plaster created the risk that the roof would collapse, and between 1924 and 1927 Sir John Simpson dismantled the entire hall, straightening warped timbers, removing the plaster, replacing any unserviceable sections and then putting the entire hall back together. It was reopened on 22 November 1928 by Queen Mary. As well as its use for revels, moots and feasts, the Old Hall was also used as a court.
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Dendritic branching is important during prenatal and neonatal development, is involved in plasticity induced by lesions, but is not involved in experience- dependent plasticity. In vivo two-photon microscopy reveals that dendritic spines in mouse barrel cortex are highly dynamic and subject to continuous turnover, and may be associated with formation or deletion of synapses. It is likely that spine turnover is necessary but not sufficient to produce experience-dependent plasticity, and other mechanisms such as axonal remodelling are also needed to explain features such as savings from prior experience.
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The Thameslink Programme, originally Thameslink 2000, is a £6 billion project in south-east England to upgrade and expand the Thameslink rail network to provide new and longer trains between a wider range of stations to the north and to the south of London. The development will facilitate cross-London journeys, which means that passengers will no longer have to change trains in London. Work includes platform lengthening, station remodelling, new railway infrastructure, and new rolling stock. The project was originally proposed in 1991 following the successful introduction of the initial Thameslink service in 1988.
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Despite having a number of names - Trufumena, Trefonia, Febronia – on 21 January 1673 the Sacred Congregation of Rites in Rome confirmed that the saint would be known henceforth in the martyrs calendar as Trofimena. In 1694 the Neapolitan playwright Carmino Scassafer published a "sacred tragedy" entitled L'Innocenza per seguitata overo Santa Trofimena, dealing dramatically with the life of the saint. Bishop Silvestro Stana began the remodelling of the cathedral in the late-18th century, and a few years later the relics were rediscovered on the night of 27 November 1793.
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Supported by a very large annual income of £22,000, he performed a major remodelling of the Castle to the designs of Anthony Salvin (1799–1881), which cost £25,350, and involved much demolition work (for example of the Chapel built in about 1716) and resulted in the addition of modern Victorian servants' quarters, a massive new block for the kitchens, and the installation of central heating, gas lighting and a bathroom with running hot water.Douglas, pp.8–11 He added a library, gun room, billiards room, "Justice Room" and many other major changes.
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Netherton syndrome is an autosomal recessive disorder associated with mutations in the SPINK5 gene, which encodes the serine protease inhibitor lympho-epithelial Kazal-type-related inhibitor (LEKTI). These mutations result in a dysfunctional protein that has a reduced capacity to inhibit serine proteases expressed in the skin. Potential endogenous targets of LEKTI include KLK5, KLK7 and KLK14. These enzymes are involved in various aspects of epidermal remodelling, including desquamation, PAR-2 activation and degradation of lipid hydrolases, suggesting a potential mechanism for the development of atopic manifestations characteristic of Netherton syndrome.
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The main Neo-Georgian school building was extensively refurbished both internally and externally, restoring it back to its former elegance with the integration of new technology. A new two-storey rear extension, connected to the existing main building, was constructed. This encloses the two quad areas, one of which is covered with an ETFE transparent roof and became the school's new dining facility. The Dearing Centre, which was built in 2001 to house Science and Geography, was internally remodelled, the remodelling started in the 2012 October half term.
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Mr & Mrs Hope made it their home, she died in 1916 and the Estate was then sold to Richard Calvert who in 1919 had the Bristol Architect Sir George Oatley do remodelling work on the property. In World War II it was taken over by the Royal Air Force and used as the headquarters for No. 955 Squadron, which was a barrage balloon unit and part of Balloon Command. The gatehouse was used by the local Air Raid Precautions. In 1963 the Estate was sold to Simon and Phillipa Wills (of W.D. & H.O. Wills).
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Known as the "Gilbert Scott of the Dissenters", he was the first architect to design a spire for a nonconformist church in London, and is thought to have influenced the Baptists and Congregationalists to begin building churches in the Gothic style. Most of his commissions were nonconformist churches, although he had one remodelling commission of an Anglican chapel. In 1856 he rebuilt George Whitefield's chapel in Tottenham Court Road. The site had recently been bought by the London Congregational Building Society, following the destruction of the existing chapel by fire.
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Another major remodelling was carried between 1907 and 1920 under the supervision of "Puck" Chaudoir, a wealthy banker from Liège and the then owner. Of the important outbuildings and supporting structures of the medieval and 18th century phases there now remain only the stables and barns surrounding a courtyard. The least modernised parts of the principal building are the river frontage and the donjon. As well as a small internal chapel set up in 1633 by the de Maillen family, there is a chapel dedicated to Saint Peter opposite the castle, founded in 1396.
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Best Overend was born in Launceston, Tasmania on 15 October 1909. He was the son of Harold Acheson Overend, a Methodist minister and Emily Trahair, a businesswoman, and was educated at Wesley College, Melbourne. In 1926 he became an articled pupil in the practice of architect H. Vivian Taylor, who was an expert in acoustics and specialized in the design of theatres and broadcasting stations. During this time, he worked on the additions of Station 2AY Broadcasting Studio in Albury, 1930, the remodelling of the Crown theatre for HO Peterson Esq.
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The Federal government is also remodelling and expanding the Makurdi Airport to become the largest agricultural cargo airport in the country. The rivers Benue and Katsina-Ala only need to be dredged and a modern river port built at Makurdi, Turan, Buruku and Katsina-Ala to transport goods all over the nation since the state is at the middle of the country. Ships are sighted very occasionally offloading cargo for Benue company at the Abinsi jetty. The eastern rail line connects Makurdi, Otukpo, Taraku, Utonkon and Igumale with the rest of the country.
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This large burst of thrombin is responsible for fibrin polymerization to form a thrombus. Factor Xa also plays a role in other biological processes that are not directly related to coagulation, like wound healing, tissue remodelling, inflammation, angiogenesis and atherosclerosis. Inhibition of the synthesis or activity of Factor X is the mechanism of action for many anticoagulants in use today. Warfarin, a synthetic derivative of coumarin, is the most widely used oral anticoagulant in the US. In some European countries, other coumarin derivatives (phenprocoumon and acenocoumarol) are used.
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Following the war a Canon Monument was installed in the park . There is no known connection between Redfern Park and this canon, nor with local servicemen, etc. In 1946 the South Sydney Rugby League Club approached Redfern Council about making Redfern Oval their home ground if suitable improvements were carried out. Construction works to upgrade the oval, including the upgrading of the oval surface, the construction of new embankments and facilities, and the remodelling of the original pavilion to function as a larger grandstand, commenced the following year.
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The Harsha Chhina Mogha Morcha was an agrarian revolt in Harsha Chhina, Punjab, India, that took place in 1946 under the leadership of the Communist Party. Harsha Chhina is a village near RajaSansi Airport, Amritsar.The Morcha started in response to a decision taken by the British Government to decrease the supply of irrigation water to farmers by remodelling the moghas (canal outlets). The Morcha was headed by Comrade Achhar Singh Chhina, Sohan Singh Josh, Mohan Singh Baath, Baba Karam Singh Cheema, Jagbir Singh Chhina, and Gurdial Singh Tapiala.
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In 1982, the United Reformed Church voted in favour of a covenant with the Church of England, the Methodist Church and the Moravian Church, which would have meant remodelling its moderators as bishops and incorporating its ministry into the apostolic succession. However, the Church of England rejected the covenant.The Rev Caryl Micklem: Obituary in The Independent, 18 June 2003Tony Tucker (2003) Reformed Ministry: Traditions of Ministry and Ordination in the United Reformed Church. In 2012, the United Reformed Church voted to allow the blessing of same-sex civil partnerships.
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In the remodelling the building to the west of City Tower, Eagle Star House, was replaced by a building whose roofs are a pale echo of the swooping roofs of the original. It is currently the fourth tallest building in Manchester. The Tower has retail and leisure units on the ground floor and is Manchester's main radio transmitting station, which is located on the roof. The developer Bruntwood sold City Tower to the asset management company Schroders for £132 million in 2014 but kept their headquarters in the building.
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Referred to as Smart Lipo™ uses laser technology to coagulate and tighten the skin and boost collagen performance.Leclère FM, Moreno-Moraga J, Mordon S, et al. Laser-assisted lipolysis for cankle remodelling: a prospective study in 30 patients. Lasers Med Sci. 2014;29(1):131-136. doi:10.1007/s10103-013-1279-4 Uses include "cankles", debulking surgery for elephantiasis nostras Wollina U, Heinig B, Schönlebe J, Nowak A. Debulking surgery for elephantiasis nostras with large ectatic podoplanin-negative lymphatic vessels in patients with lipo-lymphedema. Eplasty. 2014;14:e11.
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The common function which applies to all bisphosphonate drugs is a physicochemical interaction with the bone mineral to prevent the physical resorption of the bone by the osteoclasts. This is especially relevant at sites where bone remodelling is most active. The bisphosphonates have an intrinsic affinity for the calcium ions (hydroxyapatite) of the bone mineral just as the endogenous pyrophosphates. The difference lies in the non- hydrolysable carbon-phosphorus bond of the bisphosphonates which prevents their metabolism and at the same time ensure an effective absorption from the gastrointestinal tract.
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Old turntable and Rurtalbahn train in the station The great destruction of Düren during World War II reduced the city's financial resources. Decades old plans for remodelling the tracks and the construction of a new station building were therefore not implemented. Nevertheless, on 15 May 1949, D-Züge (express trains operated using coaches with corridors) began serving Düren station again. There were two express services: one from Brussels via Aachen, Cologne and Wiesbaden to Frankfurt, the second from Aachen via Cologne, Wiesbaden, Heidelberg, Stuttgart and Ulm to Munich.
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John Riley. The Star of the Order of the Garter was added after 1707. Marlborough's first official act was to assist in the remodelling of the army – the power of confirming or purging officers and men gave the Earl the opportunity to build a new patronage network which would prove beneficial over the next two decades. His task was urgent, for less than six months after James II's departure, England joined the war against France as part of a powerful coalition aimed at curtailing the ambitions of Louis XIV.
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The line was built by consortium LISEA consisting of (Vinci SA subsidiary) - 33.4%, Caisse des dépôts et consignations - 25.4%, Meridiam - 22.0% and Ardian - 19.2%. The consortium will operate and maintain the line until 2061, and charges tolls to train companies. The consortium invested €3.8 billion, French government, local authorities and the European Union paid €3 billion and €1 billion was contributed by (subsidiary of SNCF). Another €1.2 billion was spent by SNCF Réseau on the construction of interconnecting lines, control centres, capacity enhancements at Bordeaux and remodelling the track layout at Gare Montparnasse.
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It is of dark brick, in the English Gothic style and has a tower and spire. Buckeridge also built the Quetta Memorial Church, now All Souls and St Bartholomew's Memorial Cathedral, on Thursday Island, in memory of the lives lost in the wreck of the RMS Quetta.Hidden Treasure, (retrieved 27 September 2013) In 1892 Buckeridge commenced work in Sydney, remodelling the interior of St James' Church, King Street, removing the galleries, creating an apse and a raised platform for the choir. At this time he was also employed on work at Christ Church Cathedral, Newcastle.
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Mutations of genes involved in transcription regulation, chromatin remodelling, α-dystroglycan glycosylation, cytoskeleton and scaffolding protein, RNA splicing, and the MAP kinase signalling pathway are currently known to cause ONH. Many transcription factors for eye development are also involved in the morphogenesis of forebrain, which may explain why ONH is commonly a part of a syndrome involving brain malformations. ONH impacts all ethnic groups, although in the United States, occurrence is lower in persons of Asian descent.Ahmad, Tariq, Pamela Garcia-Filion, Mark Borchert, Francine Kaufman, Linda Burkett, and Mitchell Geffner.
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The site was converted into a parcels depot, which opened on 6 July 1970. Royal Mail constructed a sorting office on the opposite side of the main line and connected it to Mayfield with an overhead conveyor bridge, which crossed the throat of Piccadilly station. The depot closed in 1986, following the decision by Parcelforce, Royal Mail's parcels division, to abandon rail transport in favour of road haulage. The building has remained disused since then, with the tracks into Mayfield removed in 1989, as part of the remodelling of the Piccadilly station layout.
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Each round of decoration required stripping of earlier finishes. In the same 1794 Sheremetev realized that the palace fails to accommodate all the guests and ordered another round of expansion and remodelling. Giacomo Quarenghi and Pyotr Argunov presented their ambitious expansion drafts, however, actual expansion carried out by (most likely) Ivan Starov was quite modest and did not change palace exterior - at least, its southern facade. Subsequent expansion concentrated on the sprawling side wings, most notably the Italian rotunda (1796) that would become a study of Alexander II sixty years later.
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Ogilvy logo used until 2019 In 2000, the retailer again changed hands, this time acquired by Pyxis Real Estate Equities Inc. In 2004, the store underwent another remodelling at a cost of $12 million. In 2010, it was bought by a Quebec-based consortium but within a year was sold again, this time to the Selfridges Group Limited, chaired by W. Galen Weston, a subsidiary of Wittington Investments Limited. Wittington's other holdings include upscale retailers Selfridges in the United Kingdom, Brown Thomas in Dublin, Ireland, de Bijenkorf of the Netherlands, and Holt Renfrew in Canada.
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Consequently, should an individual remain in a region for 10 years or longer, the isotopic oxygen ratios in the bone hydroxyapatite would reflect the oxygen ratios present in that region. Teeth are not subject to continual remodelling and so their isotopic oxygen ratios remain constant from the time of formation. The isotopic oxygen ratios, then, of teeth represent the ratios of the region in which the individual was born and raised. Where deciduous teeth are present, it is also possible to determine the age at which a child was weaned.
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Even after the making of a video for "Proof" (by Krishna Stott, featuring Christopher Eccleston), their then record label, Echo, subsequently shelved the release of the single. "Proof" was released on 21 June 2004 as a download-only single,I Am Kloot favouritesky – discography but it did not receive its intended, full release. Finally, in 2010, a remodelling of the song was produced for their fifth studio album, Mercury nominated Sky at Night. This new version of "Proof" was released as a download-only single on 6 September 2010 – the second single, following "Northern Skies".
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Between 1741-1742 the existing one-story outbuilding was connected with the main outbuilding of the palace complex, and between 1771-1790 another wing was erected to connect the inhabited corps de logis with the second outbuilding. In 1818–1820 the palace was converted into the Sapieha Barracks (Koszary sapieżyńskie) for the use of the army. The Neo- Classical remodelling in the early 19th century was the work of Wilhelm Henryk Minter. During the November Uprising of 1830–1831 it served as the barracks for the famous Polish 4th Infantry Regiment (Czwartacy).
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The building, work of architect Gaietà Buïgas and Eduard Maria Balcells, dates back to 1894. It is one of the most noteworthy constructions of local Art Nouveau.Diari de Sabadell, El museu aspira a formar part de la vida quotidiana dels Cerdanyolencs. 10/03/2009 In 2003, the building was approved for remodelling with the help of sponsorship from individuals and entities such as the Government of Catalonia, Barcelona Provincial Council, the Barcelona Metropolitan Area Municipal Association, the Banc de Sabadell Foundation, Obra Social Caixa Sabadell and Obra Social Caixa Catalunya.Cerdanyola.
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In addition, granzymes may also be expressed in non- immune cells such as keratinocytes, pneumocytes and chondrocytes. As many of these cell types either do not express perforin or do not form immunological synapses, granzyme B is released extracellularly. Extracellular granzyme B can accumulate in the extracellular space in diseases associated with dysregulated or chronic inflammation leading to the degradation of extracellular matrix proteins and impaired tissue healing and remodelling. Extracellular granzyme B has been implicated in the pathogenesis of atherosclerosis, aneurysm, vascular leakage, chronic wound healing, and skin aging.
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Beaumont Hotham, 3rd Baron Hotham was a general in the British Army who fought at Salamanca, Vitoria and Waterloo. He was MP for Leominster from 1820 to 1841 and for the East Riding of Yorkshire from 1841 to 1868. The building was then remodelled in 1872–77 by Payne & Talbot of Birmingham for the 5th Baron Hotham, involving the addition of balustrades and the replacement of Atkinson’s east entrance porch with a colonnade. In 1954–45 further extensive remodelling of the hall took place during the tenure of the 8th Baron.
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The following years were characterised by renovation and remodelling works to turn the house into a memorial site. At the time, major parts of the building were still as they had been in the second half of the 18th century. In order to preserve spacious museum rooms, the floor plans of the main house were changed and an office for the association, plus a library and a flat for the janitor were installed. Construction changes in Beethoven's flat were limited to the stairs and the passageways to the front building.
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In 1674, some workmen remodelling the Tower of London dug up a wooden box containing two small human skeletons. The bones were found buried under the staircase leading to the chapel of the White Tower. They were not the first children's skeletons found within the tower; the bones of two children had previously been found "in an old chamber that had been walled up", which Pollard suggests could equally well have been those of the princes. The reason the bones were attributed to the princes was because the location partially matched that given by More.
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Bohun swan supporters survive on the Easter Sepulchre monument of Hugh Luttrell (died 1522) of Dunster, in St Mary's Church, East Quantoxhead, Somerset. A modern example is on the huge stone sculpted heraldic achievement of George Fownes Luttrell (1826–1910) above the new main entrance door to the castle,Maxwell Lyte, Sir Henry, A History of Dunster and of the Families of Mohun and Luttrell, London, 1909, Part 2, p.551 Part 2 built as part of his remodelling. The Bohun swan also features in the centre of the "Luttrell Table Carpet" (c.
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In the 1960s the Methodist Church of Great Britain made ecumenical overtures to the Church of England, aimed at church unity. These formally failed when they were rejected by the Church of England's General Synod in 1972. In 1981, a covenant project was proposed between the Church of England, the Methodist Church in Great Britain, the United Reformed Church and the Moravian Church. In 1982 the United Reformed Church voted in favour of the covenant, which would have meant remodelling its elders and moderators as bishops and incorporating its ministry into the apostolic succession.
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Stained glass by C E Kempe in the Grundy Library at Abingdon School, containing the name of George William Hall He became Master of Pembroke College, Oxford in 1809 and remained until his death in the third quarter of 1843. He was responsible for overseeing the remodelling of several of the College's features including Broadgates Hall, the Old Quad and the frontage of St. Aldates. He was also Vice Chancellor at Pembroke, from 1820–1824. He was rector of Taynton, Gloucestershire and canon of Gloucester from 1810 until his death in 1843.
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Miners' Bridge over Hebden Beck As the Hebden Trust Lords shared the mineral royalties, the mines brought prosperity which gave rise to the remodelling and redevelopment of much of the village. Green Terrace, which includes the old post office, was built in the 1870s, and Main Street was transformed from a back lane into the high street.Joy (2002), pp. 69-70. The village school, with working clock and bell tower, was built by the community in 1874, and the Methodist Chapel was rebuilt in 1876 to front onto Main Street.
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Embankments exist of the left bank of the Mechi River for in West Bengal. These need remodelling to prevent floods in the Naxalbari area of Darjeeling district. There also is a need for new embankments. As the Mechi forms the international border, it was agreed at a meeting of the Nepal-India Joint Standing Technical Committee to take due care in aligning the embankments so that they would be at identified distance from the border and the top levels of the embankments should be kept same on both sides, as far as practicable.
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It was first necessary to create additional space and to dehumidify the crypt. After completion of the New Vault in 1960 and the transfer of 26 tombs from the overflowing Tuscan Vault, the work of dehumidification could begin. Also, a workshop was created in the south end of the Tuscan Vault where highly skilled artisans could work on selected tombs temporarily moved there for restoration. In 2003 remodelling of the ground-level visitor facilities took place to create a new visitor entrance and make the crypt accessible to disabled visitors.
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This gene encodes a member of the human ARF gene family, which is part of the Ras superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP- ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. ARF6 can interact with βarrestin upon receptor activation.
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Upregulation of PDE5 gene expression has been observed in animal models of pulmonary hypertension, and is thought to contribute to vasoconstriction in the lung. Several randomised controlled trials investigating PDE5 inhibitors use in pulmonary arterial hypertension, a subtype of pulmonary hypertension, have demonstrated their potent effects in reducing pulmonary hypertension and vascular remodelling and improving symptoms and mortality in patients with the condition. Long-term treatment with a PDE5 inhibitor has been shown to enhance natriuretic peptide-cGMP pathway, downregulate Ca2+ signaling pathway and alter vascular tone in pulmonary arteries in rat models.
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PDE5 inhibitors have shown promise in the treatment of heart failure with reduced ejection fraction through several beneficial effects on lung vasculature, cardiac remodelling and diastolic function. A study showed that effective treatment of pulmonary arterial hypertension with sildenafil improved functional capacity and reduced right ventricular mass in patients. The effects on right ventricular remodeling were significantly greater in comparison with the non- selective endothelial receptor antagonist bosentan. However, PDE5 inhibitors may be harmful in patients with heart failure with preserved ejection fraction due to potential negative inotropic effects.
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The tissue that surrounds the infarct (stroke damaged area) has reduced blood flow and is called the penumbra. Though the dendrites in the penumbra have been damaged due to the stroke, they can recover during the restoration of blood flow (reperfusion) if done within hours to a few days of the stroke due to time sensitivity. Due to reperfusion in the peri-infarct cortex (found next to the infarct), the neurons can help with active structural and functional remodelling after stroke. Initial stages of cortical development Cortical remapping is activity-dependent and competitive.
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To the north of the village in the area known as "Church End" stands the (now redundant) parish church of St Andrew, clearly visible from passing trains. The church was listed as one of Songs of Praise's favourite churches. The church dates from around 1200 and is layered in history: the south aisle was added in 1250, a clerestory was added in the 16th century, and it received a major remodelling in the 1850s.The Nation's Favourite Churches, Andrew Barr It is now in the keeping of the Friends of Friendless Churches.
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The reconstruction works included construction of a stage, remodelling the street façade into the Spanish Mission Style, a new dance floor, new northern entrance, a projection room above the foyer and seating arrangement for 400. It retains the simplicity of a Picture Theatre built in a small country town during the Great Depression. The building is architecturally significant as one of only four Picture Theatres in the New South Wales with Spanish Mission Style facades. The James Theatre Dungog Community Centre has been owned by the Dungog Shire Council since 1979.
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The bromodomain is a motif that is responsible for acetylated lysine recognition on histones by nucleosome remodelling proteins. Posttranslational modifications of N- and C-terminal histone tails attracts various transcription initiation factors that contain bromodomains, including human transcriptional coactivator PCAF, TAF1, GCN5 and CREB-binding protein(CBP), to the promoter and have a significance in regulating gene expression. Structural analysis of transcription factors has shown that highly conserved bromodomains are essential for protein to bind to acetylated lysine.This suggests that specific histone site acetylation has a regulatory role in gene transcriptional activation.
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Both cell types produce IFN-γ as their principle cytokine and require the transcription factor T-bet to do so. The cells can also produce IFN-γ when the cytokines IL-15 or IL-12 are up-regulated in tissues after infection or injury, and secrete TGFβ1 in tandem with IFN-γ when stimulated which drives gut epithelial and extra-cellular matrix remodelling. IL-18 co-stimulation also significantly increases IFN-γ levels. The release of IFN-γ stimulates macrophages, and other mononuclear phagocytes, to induce an antimicrobial effect to eradicate intracellular infections.
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He also represented Blekinge County in the parliamentary First Chamber 1891–1899, and Karlskrona in the Second Chamber 1900–1902. After the resignation of Erik Gustaf Boström in 1900, Otter was offered the premiership by the king and formed a cabinet which would remain in office for two years. As Prime Minister he was responsible for carrying through the remodelling of the military system and the final abolition of the allotment system introduced by Charles XI more than 200 years earlier. In connection with the new military organization, a progressive taxation system was introduced.
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This includes an irregular large reflecting pool, that is navigable and includes a small island connected by metal bridges. On this island is a metal shelter from the rain, similar to two others in the garden: one, a smaller shelter, similar to that on the island and another building in masonry situated alongside the wall, that acted as a porch to the Estrada de Benfica. Following all the renovations and remodelling, the palácio acquired one of the largest collections of Portuguese Romantic and naturalist art and the grounds were opened to the public.
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The temple suffered significant damage during medieval times, particularly c. 1300 (under Pope Boniface VIII), and in Pope Nicholas V's remodelling of the Forum (which involved the demolition of both angles of the temple on the Forum side and the reconstruction of its front as a fortress with corner towers). All that survives today is the podium's core (with some of its peperino lining), parts of the cella (two fragments of its travertine wall and part of the pedestal at its back for the cult statues), and three Corinthian columns at pronaos's south-east corner.
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Assembly Hall website During the Second World War, the theatre was used for dances for troops, film shows and events to raise money for the war effort.Kent and Sussex Courier By 2001, the theatre was attracting audiences of over 150,000 each year. The theatre was refurbished in 2001 with works including the provision of additional dressing rooms, remodelling the bar, repainting of the foyer and front of house areas, and new seating, air conditioning and other facilities. The auditorium closed again in August 2015 for a £1.5 million refurbishment.
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Errekaleor Bizirik stated that this was another attempt to evict the self-managed project. In the following days, the mayor released a statement that he had ordered Ensanche 21 to begin planning an eviction for the neighbourhood. Following the power cut and removal of electrical cable by the company Iberdrola, Errekaleor Bizirik made a callout for electric generators. Since Iberdrola refused to reconnect the electricity, Errekaleor Bizirik installed a sustainable and independent electric grid, installing bicycle electricity generators and solar panels, as well as remodelling the communal showers and washing facilities to function without electricity.
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The Domhnach Airgid (the Silver church) was made to enclose a manuscript that consists of fragments of 39 sheets of the Gospels, written in the distinctively Irish lettering of the eighth or ninth century. On the cover of the Domhnach Airgid is one of the earliest surviving metalwork images of St. Patrick. Traditionally, the book was claimed to be that given by St Patrick himself to his companion St Macartan, making it an object of great veneration. Around 1350, the abbot of Clones, John O Carbry, commissioned a substantial remodelling of the Domhnach Airgid.
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They embraced the addition of a nave and bell-tower, and the remodelling of the interior, in which handsome modern benches took the place of the old 'box- pews.' The lighting of the church has been much improved by the new windows in the nave and the enlargement of the old windows in the transepts. A fine-toned bell, which cost about £100, and weighs 8.5 cwts., has been presented to the church by Mr Edward W. Sprot, younger son of the late Mr Mark Sprot of Riddell.
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The area is part of the traditional region of Lower Carniola and is now included in the Southeast Slovenia Statistical Region.Črnomelj municipal site The local parish church is dedicated to the Holy Cross () and belongs to the Roman Catholic Diocese of Novo Mesto. It was built in the early 16th century, but owes its current Baroque look to a major remodelling in the first half of the 18th century.Slovenian Ministry of Culture register of national heritage reference number ešd 2656 Vinica was the birthplace of the Slovene poet, translator, and playwright Oton Župančič.
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Orchard's other projects in the Cairns region included: Tobruk Memorial Pool (in partnership with Jack McElroy), St David's Anglican Church at Mossman, motor showrooms and a hotel in Atherton, the Tinaroo Dam lookout shelter, the Great Northern Hotel at Mareeba, the remodelling of the Courthouse Hotel in Cairns, and the Australian Hotel in Mackay. Much of his north Queensland work was influenced by the work of Dutch- born modernist architect Willem Marinus Dudok, whose use of dramatic massing, asymmetry, and overhanging eaves achieved international recognition and influence in the 1920s and 1930s.
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For teeth to move, a force must be applied to them in the direction of the desired movement. The force stimulates cells in the periodontal ligament to cause bone remodeling, removing bone in the direction of travel of the tooth and adding it to the space created. In order to generate a force on a tooth, an anchor point (something that will not move) is needed. Since implants do not have a periodontal ligament, and bone remodelling will not be stimulated when tension is applied, they are ideal anchor points in orthodontics.
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There are eight basement rooms, including a coal room, laundry room, vegetable cellar, and bathroom. A frame carriage house at the rear of the property has been converted to a five-stall garage with a one-bedroom apartment above it. As of 1987, the house and carriage house were assessed as having retained their historic integrity. It was decided that the 1923 remodelling had not significantly changed the character of the 1923 house; many of the original interior furnishing were still present, including hardwood floors, fireplaces, woodwork, and lighting fixtures.
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This included the construction of a striking three-story bay window rising to an octagonal turret with a patterned roof, and a two-story bay window near the southwest corner. The most significant additions made during the 1895 remodelling are located at the rear (north) of the house. These include a conservatory with a polygonal glass dome, a greenhouse just east of the conservatory, and an enlarged kitchen. The eastern end of the house was also remodeled in 1895, in locally cut red sandstone to match the facade.
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The appearance of the early vertebrate jaw has been described as "a crucial innovation" and "perhaps the most profound and radical evolutionary step in the vertebrate history". Fish without jaws had more difficulty surviving than fish with jaws, and most jawless fish became extinct during the Triassic period. However studies of the cyclostomes, the jawless hagfishes and lampreys that did survive, have yielded little insight into the deep remodelling of the vertebrate skull that must have taken place as early jaws evolved. The customary view is that jaws are homologous to the gill arches.
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The line between Stirling and Kincardine has reopened; an hourly passenger service operates between Stirling and Alloa only, and freight runs over the whole route. The current remodelling of Edinburgh Waverley station is complete; further improvement in pedestrian access is planned.Waverley Steps project Revamped, electrified line, double- tracked throughout, between Airdrie and Bathgate, including reopening the Drumgelloch to Bathgate route, is to be completed by late 2010. The Edinburgh Airport Rail Link has been suspended and mothballed,EARL project suspended in favour of a tramlink interchange and extension.
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Hilliard, c.1600 Two portraits of Elizabeth in her coronation robes survive, both dated to 1600 or shortly thereafter. One is a panel portrait in oils (above) and the other is a miniature by Nicholas Hilliard. The warrant to the queen's tailor for remodelling Mary I's cloth of gold coronation robes for Elizabeth survives, and costume historian Janet Arnold's study points out that the paintings accurately reflect the written records, although the jewels differ in the two paintings,Arnold 1978 suggesting two different sources, one possibly a miniature by Levina Teerlinc.
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In 1983 Hele's was merged with Bishop Blackall school on the Quarry Lane site and was renamed St Peter's (called St Peter's Church of England Aided School). Considerable remodelling of the school building took place and the Annex was abandoned and later demolished to make way for a housing development. The main school buildings were demolished in 2005 to make way for a brand new St Peter's School building. The War Memorial was relocated to the balcony of the new school hall, along with a series of portraits of previous headmasters.
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When at Aberdeen he sought recreation in the game of golf. In February 1637 he took some part in furthering John Durie's plans for uniting the reformed and Lutheran churches. Forbes, though he deplored Charles I's measures for remodelling the church of Scotland, considered the National Covenant an unlawful bond, and in April 1638 he published a tract against it entitled A Peaceable Warning to the Subjects in Scotland. In July 1638 the Earl of Montrose, Alexander Henderson, and other covenanting leaders visited Aberdeen to make converts to their cause.
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In 1951 Sherwood Washburn, a former student of Hooton, introduced a "new physical anthropology."Washburn, S. L. (1951) “The New Physical Anthropology”, Transactions of the New York Academy of Sciences, Series II, 13:298–304. He changed the focus from racial typology to concentrate upon the study of human evolution, moving away from classification towards evolutionary process. Anthropology expanded to include paleoanthropology and primatology.Haraway, D. (1988) “Remodelling the Human Way of Life: Sherwood Washburn and the New Physical Anthropology, 1950–1980”, in Bones, Bodies, Behavior: Essays on Biological Anthropology, of the History of Anthropology, v.
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In January 1976, Eaton's announced that they would discontinue printing their coloured catalogues in Winnipeg and would close down the catalogue and mail order building as of March 1st. All unclaimed stock at the Catalogue Office would be sold at discount. This sale went on into the Summer of '76. Remodelling construction began in November, 1977 with the Clearance Salesroom demolished to make way for the spiral parkade. Eaton Place opened on October 11, 1979 as Downtown Winnipeg's first indoor shopping mall, after Eaton's closed down its Catalogue and Mail-order operations three years earlier.
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The Disruption of 1843 caused an inevitable loss of congregation. However the church recovered and reconstruction (and restoration) of the building took place 1847–48 included the installation of a magnificent hammerbeam nave roof, together with an entire remodelling of the exterior, including a new square tower, all of which was designed by the architect Thomas Hamilton. The church is a category A listed building. The roof design is said to be based on St Isaac's in St Petersburg. During this restoration the west window was salvaged and re-used at St Conan’s Kirk.
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Most of the building's interior was stripped out and sold for parts, and the building fell into disrepair due to lack of proper maintenance. After the war, the building was bought by singer and evangelist Aage Samuelsen with the intent of restoring the hotel to its former glory. Though Samuelsen failed to raise the necessary funds to renovate the building, he gave the hotel significant press exposure, and towards the end of the 1980s restoration efforts began in earnest. The hotel was reopened once the remodelling finished in 1992.
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Shear stress is proportional to the speed inside the vessel as well as the pressure drop between two fixed points on the vessel wall. The precise mechanism of vessel remodelling is believed to be high stress on the inner wall of the vessel which can induce growth, which heads toward uniform compressive and tensile stress on both sides of the vessel wall. Generally, it has been found that circumferential residual stress is compressive and tensile, indicating that inner layers of the endothelial tube grow more than outer layers.Chuong, C.J. and Fung, Y.C. (1986).
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Blockage of blood vessels is currently treated by surgically inserting stents to force vessel diameters open and restore normal blood flow. By understanding the implication of increased shear stress on homeostatic regulators, alternative, less-invasive methods may be developed to treat vessel blockage. The growth of tumours often results in reactivation of blood vessel growth and vascular remodelling in order to perfuse the new tissue with blood and sustain its proliferation. Tumour growth has been shown to be self-organizing and to behave more similarly to embryonic tissues than to adult tissues.
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The South Wing officially became the Sydney branch of the Royal Mint in 1854. Its establishment required the extensive internal remodelling of the former hospital wing for accommodation for the Mint Master, administrative offices and receiving and storage rooms for bullion. Land to the rear of the building was also developed, with prefabricated industrial buildings for rolling, assaying and coining imported from England and erected around a courtyard directly behind the former hospital building. The Mint was shut down in 1926 when the Royal Melbourne Mint became the mint of the Commonwealth.
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The north-west range dates from the early-16th century; the north-east range is of the late-15th century as is the great hall on the south side of the court. The double-height bay windows date from Bodley and Garner's remodelling for Morgan Williams. Alan Hall describes the inner court as having a "peaceful and domestic" appearance having been constructed in the more settled Tudor period under the later Stradlings. The exterior walls of the inner ward are decorated with a set of terracotta medallions or busts.
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Alfred Nicolas Rambaud was born in Besançon. After studying at the École Normale Supérieure, he completed his studies in Germany. He was one of that band of young scholars, among whom were also Ernest Lavisse, Gabriel Monod and Gaston Paris, whose enthusiasm was aroused by the principles and organization of scientific study as applied beyond the Rhine, and who were ready to devote themselves to their cherished plan of remodelling higher education in France. He was appointed répétiteur at the École des Hautes Études on its foundation in 1868.
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The foundation of the monastery is attributed to D. Afonso Henriques in the second half of the 12th century. The only enduring element of the primitive medieval construction with its clearly Romanesque style is the main chapel, the remainder of the group was subjected to remodelling work when it passed into the hands of the Society of Jesus. Nowadays, the monastery is private property, with the exception of the church which continues to be part of the parochial headquarters of the parish. It is classified by IPPAR as a National Monument since 1926.
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Structural evidence shows that this work was a remodelling rather than a total rebuilding. New choirstalls with carved misericords and canopy work were installed beneath the octagon, in a similar position to their predecessors. Work was resumed on the Lady Chapel, and the two westernmost bays of Northwold's presbytery were adapted by unroofing the triforia so as to enhance the lighting of Etheldreda's shrine. Starting at about the same time the remaining lancet windows of the aisles and triforia of the presbytery were gradually replaced by broad windows with flowing tracery.
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Over time, the skin will reform over the puncture site, but the hole in the skull will remain. The location of the trepanation on the skull varies by geographical region and period, common locations are the frontal and the occipital bones. In most cases, trepanation was a one-off operation, with only a small percentage of the trepanned skulls having undergone more than one surgery. In those with multiple openings, the extent of bone remodelling indicate whether the opening was done at around the same time or at different times during the individual's life.
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After surgery, hyperemia and osteoclastic activity are seen on the necrotic bone surrounding the trepanation site, due to loss of blood supply. The perforations were found with the growth of fine bone spurs, which indicate that trepanation had been carried out on live subjects, rather than being a ritual conducted after death. There is evidence that some individuals survived multiple skull surgeries. There is evidence of bone remodelling around the skull defects, corroborated by the smooth borders around the opening, sealed by a dense cortex of bone, denoting procedural success after trepanation.
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156–7 Under the Pomeroys the castle consisted of a dry moat (now mostly infilled), gatehouse and ramparts surmounted by the curtain wall with buildings disposed around the wall on the inside. Due to the extensive remodelling that took place later, very few archaeological remains survive to show the exact placement of these original buildings. In 1978, a wall painting was discovered in the upper storey of the gatehouse, hidden behind a thick layer of vegetation. It is a representation of the Adoration of the Magi and has been dated to c.
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Of the Hussite era, only the eastern part remains; the western area of the castle, with its plain corbels dates to a remodelling in 1567. Behind the gateway rise the ruins of the late Romanesque bergfried or keep, whose north wall still reaches a height of about 10 metres. The originally square main tower had sides 9.8 metres long. Only parts of the outer shell have survived; the wall being constructed of closely packed rusticated ashlars with narrow channels the remains of the infill being made of herringbone pattern bricks (Opus spicatum).
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Increase expression of MMP1 and MMP9 led to degradation of collagen fibres, and subsequently dilatation of the heart. Several signal pathways such as Angiotensin II, Transforming growth factor beta (TGF-beta), and Endothelin 1 are known to trigger synthesis and degradation of collagen fibres in the heart. Other factors such as high blood pressure, activation of sympathetic system which releases norepinephrine, activation of renin–angiotensin system which releases renin and anti-diuretic hormones are important contributors of cardiac remodelling. However, atrial natriuretic peptide is thought to be cardio- protective.
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From 1999 to 2001 the building served as the Federal Chancellery (Berlin) under former German Chancellor Gerhard Schröder. Since its renovation, it has acted as a venue for seminars, lectures, conferences, and social events for academic institutions, government agencies, as well as groups and companies. The building received further improvements in 2017, with the remodelling of the third floor conducted to accommodate the significant increase in the number of students. This led to the creation of the new library, four seminar rooms, the ESMT research lab, eleven group study rooms and a student lounge.
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Causey Park House is a 16th-century former manor house with Grade II listed building status situated at Causey Park, Northumberland, England. The Manors of Ogle (owned by the Ogle family), and Causey Park and Bothal (owned by the Bertrams) were merged by the marriage of Robert Ogle and Ellen Bertram in the 14th century. The house was built in 1589 for James Ogle on the site of an earlier Bertram house which incorporated a pele tower. Early masonry remains evident despite considerable extension and remodelling during the 18th and 19th centuries.
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His grandson Sir John Dawnay was the first of several Dawnays to serve as High Sheriff of Yorkshire. Cowick Hall was built in the late 17th century for John Dawnay, 1st Viscount Downe. The original architect is unknown, but the main house was significantly altered from 1752 to 1760 by James Paine for the third Viscount, including internal remodelling, rebuilding the south entrance and resetting the roof balustrade. Italian architect Joseph Bonomi designed additional alterations in the 1790s for the fifth Viscount, including redesigning the west staircase and an addition of the external south gallery.
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Plans for the work were completed by Henry Eli White in February 1927 for "Capitol Theatre Sydney Limited" and the same month Wirths wrote to the Sydney City Council requesting a "remodelling" of the building for its proposed new function. Henry White was a very experienced theatre designer and in 1927 visited America with Stuart Doyle, the managing director of Union Theatres Ltd., to review the latest developments in theatre design. Whilst in the United States, architect John Eberson was engaged to provide White with designs for the conversion of the Hippodrome.
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In November 2011, Lord Foster published proposals to improve the transport system of south east England. Under these proposals, called the Thames Hub, new high-speed rail lines would be built connecting Kent and Europe with north London, and the north east and north west of England. The scheme would also involve the remodelling of the Thames Estuary, by the construction of a four-runway airport on the Isle of Grain, partially on land reclaimed from the estuary but including land at Allhallows and Lower Stoke. This plan is controversial.
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151 showing a half dressed King George IV embracing Nash's wife with a speech bubble coming from the King's mouth containing the words "I have great pleasure in visiting this part of my dominions". Whether this was based on just a rumour put about by people who resented Nash's success or if there is substance behind is not known. Further London commissions for Nash followed, including the remodelling of Buckingham House to create Buckingham Palace (1825–1830),Mansbridge 1991 p. 274 and for the Royal Mews (1822–24)Mansbridge 1991, p.
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In November 2011, Lord Foster published proposals to improve the transport system of South East England. Under these proposals, called the Thames Hub, new high-speed rail lines would be built connecting Kent and Europe with North London, and the North East and North West of England. The scheme would also involve the remodelling of the Thames Estuary, by the construction of a four-runway airport on the Isle of Grain, partially on land reclaimed from the estuary but including land at Allhallows and Lower Stoke. This plan is controversial.
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In 1997, the Prime Minister of Lower Saxony, Gerhard Schröder, inaugurated the new facilities of the Kestner Gesellschaft at Goseriede 11. Simultaneously, the Munich Abendzeitung declared the remodelled exhibition facility "Germany’s most beautiful exhibition house." The remodelling of the former Goseriede Aquatic Center into an up-to-date exhibition house not only incorporates the high technical demands of modern exhibition operations but also preserves and showcases the Jugendstil features of this historic landmark. With its five halls on two levels, the house has at its command more than 1,500 square meters of exhibition surface.
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He was the Chief Engineer of the London and South Western Railway, overseeing the remodelling of Clapham Junction railway station and the reconstruction of London Waterloo station. He was later appointed Chief Engineer of Southern Railway. Tailor and fashion designer Timothy Everest began his professional career working as a sales assistant at a branch of Hepworths in the town.Bespoke Tailor Fan Of PM's Style BBC News. Retrieved 3 July 2011 Sporting figures include Robert Hughes, who in 2005 won the Wales National Darts Championship,Profile – Robert Hughes Lakeside World Professional Darts Championship.
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For scenes shot on location, all pupil roles that were not leads were played by real Rugby School students. The school all but ground to a halt for a fortnight as a large portion of the school grounds were used for shooting and the majority of male pupils were involved in taking part as extras. Several interior scenes were shot at Aldenham School in Hertfordshire, which was founded in 1597, a contemporary of Rubgy. Extensive cosmetic remodelling took place in some parts of the school so as to render the set historically accurate.
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His first known commission was for the design of Montacute Housepage 11, Malcolm Rogers, Montacute House, 1991, National Trust in c1598. This is one of the finest Elizabethan mansions in the country and was designed for Sir Edward Phelips. Other works include the remodelling of a hunting lodge at Cranborne to form the Manor House for Robert Cecil, 1st Earl of Salisbury in 1607–1610. He was then commissioned in 1610–1613 by Dorothy Wadham, a Somerset resident, to design and oversee the building of Wadham College, Oxford.
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Adam also made many designs for remodelling the interiors, which are now in the collection at the Sir John Soane's Museum, but only a few of them were carried out. The Duke of Cumberland died in 1790, and in 1800, the widowed Duchess surrendered it to the banks who held mortgages on it. This map of circa 1870 shows Cumberland House as the central element of the War Office. The house was sold to the Union Club in 1801 and in 1806 it was purchased by the Board of Ordnance.
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The first significant building to occupy the site of the castle was a timber-framed dwelling, inhabited from the early 16th century by Richard Streatfeild, an iron master and wool merchant. Little remains of this first structure as, in 1679, Henry Streatfeild (1639–1719) had the house rebuilt in red brick in the Restoration style. The building was known as High Street House or High Street Mansion since it fronted the village high street. Remodelling of the house's grounds in the 19th century resulted in the current diversion of the road through the village.
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Following extensive adaptation and remodelling, the highlights of the collections of medieval and Baroque art (previously in the Lower Belvedere) have been placed on display at the Upper Belvedere since spring 2008. For the first time, the entire scope of the permanent collection, from the Middle Ages to the mid-twentieth century, can now be seen under one roof. The adapted rooms in the Lower Belvedere and Orangery now provide space for temporary exhibitions. Moreover, a study collection of the medieval holdings was set up in the former Palace Stables.
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On 9 August 1991, the museum that was established was integrated into the administration of the Instituto Português de Museus (Portuguese Institute of Museums), under decree 278/91 (Diário da República, Série-1A). By the end of the 20th century, there was further work completed in the interior on the staircases, vertical accesses and washrooms, along with remodelling of the galleries on the first floor occupied by the secretariat and administration of the museum, as well as the warehouse in 1993. This culminating in the third- phase expansion of the spaces between 1994 and 1999.
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Das Pferdegrab wird aufgehübscht. In: Taunus Zeitung. 5. April 2011, S. 19. The replica and original both bear an inscription, which translates as: In the early Strawberry Hill variant of Gothic Revival architecture, the Gothic House's designer is unknown, but Friedrich Lotz argues it was Jeffry Wyatville, who had designed the remodelling of Windsor Castle for Elizabeth's elder brother George IV of the United Kingdom - Jeffry's uncle James Wyatt had also worked in the Gothic Revival style at Windsor and at the Castellated Palace at Kew for George and Elizabeth's father George III.
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In 1897 he was promoted again to divisional engineer for London and in 1914 he became Chief Engineer of the railway, replacing J.W. Jacomb-Hood. He oversaw the building of the Bordon Light Railway in 1902, the remodelling of Clapham Junction station which was carrying over 1,000 trains a day, and the first electrification scheme carried out by the L&SWR; between 1913 and 1916. He also completed the major reconstruction of Waterloo station in 1914-15. During the First World War, Szlumper also worked for the War Office and the Admiralty.
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During the 1930s extensive remodelling of Victoria Park were completed including the lake, lawns, pathways, plantings, filling in of small pond (near current swimming pool), removal of iron railing surrounding the Park and creation of fence between the park and the University. Between 1924 and 1946 the University exchanged of lake and main drive with the Sydney City Council for of Victoria Park in the Eastern Avenue area. In 1955 the Victoria Park Swimming Pool (named in honour of King George VI) opened. The pool was the first in-ground public swimming pool in Sydney.
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The replacement statue being hoisted onto the base A passenger ship deftly steers round the Deutsches Eck With German Reunification in 1990, the German Corner no longer served as a symbol of the aspiration for a united Germany. Thus, a discussion arose regarding a remodelling of the plaza. Critics considered the reinstallation of the equestrian statue of Wilhelm I as anachronistic and improper, whereas promoters saw the opportunity for tourist benefits. As the owner of the site, any decision to reinstall a statue of Wilhelm I rested with the government of the Rhineland-Palatinate.
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In 1982, the Dresden Railway was electrified with overhead wire. This fact complicates plans to restore S-Bahn services to the station, which have been discussed repeatedly since 1990 without resolution. In the course of the project to develop the Berlin–Dresden railway for speed of up to 200 km/h that began in May 2013, an extensive remodelling of Rangsdorf station was approved by the Federal Railway Authority on 19 March 2013. In the summer of 2013 the station building, the footbridge, the loading platform, the loading dock and the pumping station were demolished.
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The former site architect of the Hope House, Helena Arghuete, managed the remodelling of the house following its 2016 sale. The modernist interior of the house as envisioned by Lautner was created by stripping the interiors and replacing the décor with natural materials. Arghuete was assisted by Lorenzo Jauregui, whose mother was the Hope's maid for 34 years. The father and son woodworkers Brian Cooney Sr. and Brian Cooney Jr. constructed 12 new doors at the house to Lautner's design and installed African mahogany on the house's interior walls.
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Piccadilly Plaza was originally built by Covell Matthews and Partners from 1959 to 1965 and has been recently re-modelled by Leslie Jones Architects in 2001 (this mainly involved replacing the old Chinese style-roofed towers of Bernard House). Piccadilly Plaza contains the renovated Mercure Hotel (formerly known as the Ramada Manchester Piccadilly and Jarvis Piccadilly Hotel); the refurbishment was completed in 2008. The huge tower block, originally known as Sunley Tower, was renamed City Tower. In 2005 the Plaza underwent large-scale remodelling with recladding of the tower and cleaning of concrete façades.
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A local builder, Wally Saunders, helped Dahl with much of the work of remodelling the house. Saunders provided the inspiration for Dahl's BFG character. Elizabeth Day, writing in The Guardian, described the house as "an oversized cottage with low ceilings and yellow- and rose-painted rooms". Dahl's widow, Felicity Dahl, said in a 2008 interview with The Guardian that "people have strong reactions" to the house; the film director Tim Burton cried on the lawn of Gypsy House after coming there to research for his film adaptation of Charlie and the Chocolate Factory.
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Six ground floor shops were constructed, designed by architect RF Franklin, and built by contractor TP Turner. A further modernisation of the shop fronts was undertaken in 1976-77, as well as extensive interior remodelling by architects Lumley and Tait Pty Ltd. On 4 November 1996 the Ipswich and West Moreton Building Society merged with the First Provincial Building Society which in turn was taken over by the First Australian Building Society in December 1997 both of which occupied the old East Street building. The building was later owned and occupied by the Bendigo Bank.
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However, before the development began, Swasey abruptly cancelled the contract and moved his practice to New York City. Two young associates in his St. Louis practice took it over and implemented some of his designs, all of which were in the Colonial Revival style. Once established in New York, Swasey began designing new theatres or remodelling existing ones for the Shubert family. He also designed the rebuilding of George C. Tillou's Steeplechase Amusement Park at Coney Island in 1907 and the Lido Club Hotel at Lido Beach during the same period.
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John Foster Sr. (1758–1827) was an English engineer, father of John Foster Jr. He was Senior Surveyor to the Corporation of Liverpool succeeding Henry Berry. In the early 1820s he was responsible for the extensive remodelling of Liverpool's Blue Coat School, adding the curved wall and new chapel to the rear. In 1824 he was succeeded as Senior Surveyor by his son while Jesse Hartley replaced him as dock engineer at Liverpool Dock Trustees.John Foster, dock engineer (1759–1827) During his time as dock engineer, Foster completed only one dock (Prince's Dock).
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The Museum of Anatolian Civilizations () is located on the south side of Ankara Castle in the Atpazarı area in Ankara, Turkey. It consists of the old Ottoman Mahmut Paşa bazaar storage building, and the Kurşunlu Han. Because of Atatürk's desire to establish a Hittite museum, the buildings were bought upon the suggestion of Hamit Zübeyir Koşay, who was then Culture Minister, to the National Education Minister, Saffet Arıkan. After the remodelling and repairs were completed (1938–1968), the building was opened to the public as the Ankara Archaeological Museum.
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Alterations were made to the station building as changing requirements necessitated them. However, insufficient attention seems to have been paid to routine maintenance, and action was often taken in response to complaints from the public. In 1957 a remodelling plan was proposed, which was expected to remedy all of the major maintenance issues at a cost of £2530. It was not until 1963 that money was set aside for the renovations in the working estimates, by which time the District Engineer was in favour of replacing the building.
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In 2009, the passenger building underwent a radical redesign, involving the remodelling of the interior without damage to the existing structures. As at 2010, it had a modern and streamlined appearance, with a new ticket office, a shopping mall and a new entrance facing Piazza Aldo Moro. The station yard has nine tracks and two passing loops. The station is connected by a double-track line with the Savona Parco Doria goods yard, workshops (OMR), a locomotive depot, and Savona Marittima railway station, the latter being situated within the port area.
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In 1991, she was appointed professor of Art History at South Korea's prestigious Ewha Women's University. In 1995 she began a five-year tenure as Director of the Ewha Womens University Museum.Kbs Global In 2003 she was selected as Director of the National Folk Museum of Korea, a position she held until be selected in August 2006 to head the nation's premiere museum. Her legacy at the National Folk Museum includes the expansion of the museum's coverage to the field of folk art and full-remodelling of buildings and modernization of exhibitions.
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Following the fashion for house renovations and keen to commission a design that would be conspicuously different from his neighbours' properties, Batlló appointed the audacious Catalan Modernista architect Antoni Gaudí to carry out the work. Gaudí's redesign drew on Modernisme and Art Nouveau, creating a dramatic facade of flowing, sculpted stonework and a colourful, organic roof in the form of a dragon's arched back. The last house to undergo remodelling was Casa Torruella at number 37, now known as Casa Bonet. It was altered by Marcel·lí Coquillat in 1915.
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A passenger lift was installed in the 1890s and electricity replaced gas for the building lighting around the same time. Manuel Hornibrook, Master Builder, was contracted for the carrying out of extensive additions and the remodelling of the banking chamber during the early months of 1924. Honour boards were installed in the bank after World War I and World War II, to commemorate employees who served in the wars. Despite the 1890s economic depression and a major political scandal late in the same decade, the QN Bank prospered, retaining the Queensland Government accounts until 1920.
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Finally in July 2010 both, the ADIF and the municipality reached an agreement by which the municipal government received the station in concession for a term of 10 years (with the possibility to be extended). By October that year, A$3,000,000 had been investing in remodelling the station. The remodelled Belgrano station building was put into service again as multi- purpose building that included both, convention and administrative centres, and the seat of local Secretary of Tourism. A parking lot with capacity for 200 vehicles was also built.
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Local supersaturation is a common trigger of crystallization, and when the nucleus of the crystalline structure is formed, crystals can self-perpetuate and cause more crystallization and aggregation. Main mechanisms by which the formed crystals and aggregates cause pathological states and ultimately disease are acute necroinflammation, chronic tissue remodelling, and mechanical obstruction. Necroinflammation is an autoamplifying process where crystals are toxic to cells (cytotoxicity) and cause cell death (necrosis and regulated cell death) and a local and systemic inflammatory response. Cytotoxicity includes actin depolymerization, free radical and reactive oxygen species synthesis, and autophagy.
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The Russian Orthodox Cathedral of the Dormition of the Mother of God and All Saints is the cathedral of the Russian Orthodox Diocese of Sourozh. It holds the diocese's administrative meetings as well as weekly, seasonal and special services. Its building is the Victorian former church of a wealthy parish of its era that faces the north-east green of Ennismore Gardens, Knightsbridge, London, England. The main (western) façade is a very close copy of that of the Basilica of San Zeno, Verona, in Verona, Italy since remodelling in 1891.
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A carriage storage siding was originally provided between Platforms 1 and 2, explaining the wide gap between the current lines in this location. The facing crossover was finally installed during the remodelling of the station approaches in 1983, thus allowing terminating trains to directly access Platform 2. The through lines were served by Platforms 3 (in the down direction) and 4 (up). The lines continued through the back wall of the station and immediately crossed over Brook Street by way of a bowstring girder bridge with an span.
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Henry Clutton was the lead architect but Burges, as assistant, contributed to the restoration of the sculpture and to the general decorative scheme. Much was lost in restorations of the 1960s. More lasting was Burges's work of 1858 onwards in the substantial remodelling of Gayhurst House, in Buckinghamshire, for Robert Carrington, 2nd Baron Carrington. Rooms there contain some of his large signature fireplaces, with carving by Burges's long- time collaborator Thomas Nicholls, in particular those in the Drawing Room which include motifs from Paradise Lost and Paradise Regained.
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Skilbeck's Warehouse, formerly at 46 Upper Thames Street, London, and now demolished, was a drysalter's warehouse constructed by Burges in 1866 and is important as his only foray into industrial design. Burges was commissioned by the Skilbeck Brothers to remodel an existing warehouse; the result was influential, Eastlake describing it as, "one of the very few instances of the successful adaptation of Gothic for commercial purposes". Bradley writes of Burges's remodelling as using "twin pointed bays under a single Gothic relieving arch and gable". The use of exposed cast iron was revolutionary.
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It appears to be a small tower house from the late 16th century, but a blocked door of 15th century type at first floor level, seems to indicate the remodelling of an earlier tower. The current entrance, in the north-east wall, is a reconstruction, positioned by the surviving corbelled machicolation above and a socket from a draw-bar to secure the original door. The original entrance may have been on the first floor. It is a small, rectangular, three-storey tower house with no vault or stone stairway.
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He gave his work the form of a dialogue. The two conflicting Christian parties were represented by Capnio (Reuchlin) and the Inquisitor Jacob van Hoogstraaten, O.P. In conciliatory terms, Galatino responded to the queries and suggestions of the former, and refuted the objections of the latter. He had borrowed largely from the Pugio Fidei of the Dominican Raymond Martini, remodelling, however, the material and supplementing it with copious quotations from the Zohar and the Iggeret ha- sodot of the Jewish convert Pablo de Heredia. In a long letter to Paul III (MS. Vat. Libr.
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Laurie and Heath 1971 Prior to its construction, the Congregationalists of colonial Sydney met in a building called the Independent Chapel, located on the western side of Pitt Street between Market and Park Street. This was opened as a place of public worship in 1833, but the rapidly growing congregation soon necessitated the erection of a larger building. The foundation stone was laid in 1841, but economic recession meant it wasn't completed until 1846.Stapleton 1983 The Church took its present form in 1867 after extensive remodelling by architect George Allen Mansfield.
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Utah Opera purchased its production studios in 1995, using the building for rehearsals, administration, and costume/set design and storage. In subsequent years, the Production Studios were expanded; remodelling the existing 38,700 square feet, and building on an additional 30,000 square feet. It boasts a very large rehearsal space, an equally large space for set- building/design, a shop for costume and wigs design/construction, extensive costume and sets storage, a dance rehearsal space, and administrative offices. Sets and costumes are regularly rented from Utah Opera by opera companies around the US.
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Currently, Lea Manor High School is undergoing building and refurbishing work under the government's Building Schools for the Future Programme (BSF) and is one of the first schools in Luton to be transformed. The building firm Wates Group won the contract to rebuild or remodel every secondary school in Luton. The school will be more student-friendly and modern, including a brand new community library and community theatre which will become the biggest in Luton. Phase one of the remodelling has been completed and was opened to students in Autumn 2009.
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Borromini facade facing the Tiber. The Palazzo Falconieri is a palace in Rome, Italy formed in the seventeenth century as a result of remodelling by the Baroque architect Francesco Borromini. It is the home of the Hungarian Academy Rome (which is the Rome office of the Balassi Institute), since its foundation in 1927. It is located between Via Giulia and Lungotevere, with entrances to both; it is near Palazzo Farnese and a few houses down and across Via Giulia from the church of Santa Caterina della Rota in the Rione of Regola.
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Restaurant Jammet was popular amongst artists, writers, actors, and business owners. Amongst the patrons of the restaurant were Orson Welles, Tyrone Power, Peter Ustinov, W. B. Yeats, Jack Butler Yeats, Harry Kernoff, and Seán O'Sullivan. As an artist, and patron and arts, Jammet decorated the restaurant, most notably the remodelling of the upstairs in 1946 with architect Noel Moffet to a minimalist looks with curved glass-block screens and exposed steelwork. Through his staging of a number of French plays in autumn 1938 at the Gate Theatre, Micheál MacLiammóir became close friends with the Jammets.
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Stadium from air The Waldstadion (), currently known as the Deutsche Bank Park for sponsorship purposes, is a retractable roof sports stadium in Frankfurt, Hesse, Germany. The home stadium of the football club Eintracht Frankfurt, it was opened in 1925. The stadium has been upgraded several times since then; the most recent remodelling was its redevelopment as a football-only stadium in preparation for the 2005 FIFA Confederations Cup and 2006 FIFA World Cup. With a capacity of 51,500 spectators for league matches and 48,500 for American Football and International Football matches, it is among the ten largest football stadiums in Germany.
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The following lines from the poem are carved into a stone tablet on Prebends Bridge: The old commercial section of the city encompasses the peninsula on three sides, following the River Wear. The peninsula was historically surrounded by the castle wall extending from the castle keep and broken by two gatehouses to the north and west of the enclosure. After extensive remodelling and "much beautification" by the Victorians the walls were removed with the exception of the gatehouse which is still standing on the Bailey. The medieval city was made up of the cathedral, castle and administrative buildings on the peninsula.
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The Elizabethan property was demolished in 1860 following the acquisition of the estate by Lord Cranbrook. He commissioned the building of a new house, the extant Hemsted House, employing David Brandon, president of the Royal Institute of British Architects to design the new mansion. The house, which featured a prominent tower and was described as having "alarming vitality" was subsequently remodelled in 1912 by Herbert Cescinsky at the behest of its new owner, newspaper magnate and later Lord Rothermere, Harold Harmsworth. The remodelling saw the "vitality" toned down and the upper levels of the tower removed.
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In 1587, was the last reference to the work on the Casa da Moeda, but a few years later (1607), a royal letter extinguished the institution. In 1628, there were new references to work in the old House of Coin. The Finance inspector issued an order in 1656 to move the customshouse to the remnants of the House, and to promptly complete its reuse; starting in the 15th century, the customshouse underwent several expansions and re-modellings that altered its original structure. The most important remodelling occurred in 1677, under the reign of King D. Peter II, when the building was virtually rebuilt.
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An early success of the Centre was the "Picasso's Croydon Period" exhibition of March–May 1995. The Croydon Tramlink began operation in May 2000 (see Transport section below). The Prospect West office development was built in 1991 to 1992, and its remodelling planned in 2012 has now been completed. Renamed Interchange Croydon when it was reopened in 2014, the 180,000 square foot office development was the first new grade A office development of its size to open in Croydon for more than 20 years. Another large shopping centre, Centrale, opened in 2004 opposite the Whitgift Centre, and adjoining the smaller Drummond Centre.
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These results suggest that divergent neuroanatomic mechanisms in the EPN and STN, upon DBS stimulation, lead to similar behavioral outcomes. In her postdoctoral work, Creed studied DBS in the context of drug addiction in the Lüscher Lab at the University of Geneva. In the context of cocaine addiction, drug-adaptive behavior is driven by remodelling of the brain’s reward circuitry, specifically plasticity of the excitatory inputs onto dopaminergic ventral tegmental area neurons. Creed and her colleagues found that cocaine administration leads to long-lasting increases in burst firing due to impaired function of calcium activated small conductance potassium channels (SK channels).
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Although the stone castle was begun in the 1230s, there were three main building phases plus several periods of remodelling. The earliest part of the masonry castle is the inner ward which was started by Llywelyn the Great. Unlike most other Welsh native strongholds, the inner ward at Criccieth was protected by a gatehouse with twin D-shaped towers that was protected by a gate and portcullis, with murder holes in the passage, and outward facing arrowslits in each tower. This design might have been copied from English designs on the Marches at Beeston Castle, Cheshire or Montgomery Castle, Powys.
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Canal Tunnels northern entrance at Belle Isle Until summer 2018 there were major track, signalling and station remodelling works at London Bridge station as part of the Masterplan project (some works within the station building started during Key Output 1). A grade-separated junction was created at Bermondsey. New permanent way (track level, in this case including both plain rail and junctions) and overhead line equipment were laid out in the new Canal Tunnels just north of St Pancras between the Thameslink route and the East Coast Main Line,Network Rail (2004a), p. 61, paragraph 2.14.4.
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Vanbrugh's northwest facade consisted of a single flat surface, in which a Venetian window on each floor filled the central space between two shallow projections. Perhaps to improve the view down to Avonmouth, the centre was remodelled by Mylne with a canted bay window, at odds with the tautness of Vanbrugh's overall design of the house, in which all planes were parallel or perpendicular to the walls. On the northeast the wall was moved forward during nineteenth-century remodelling, destroying an aesthetically significant alignment between wall projections and the break in the roof arcade, which had been present in Vanbrugh's design.
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The panelling in this room dates back to the Norcliffe family's occupation of the house (1583–1643) but the corner fireplace was put in during Lord Preston's remodelling in the late seventeenth century. In front of the fireplace is a painted leather firescreen made from a piece of a set of leather wall hangings which according to a local historian, the Rev. Eastmead once decorated a room at Nunnington but which were shreds relegated to an attic room by 1824. The oak bed is an example of an old stretcher base being updated at intervals by the addition of later posts and canopy.
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Major road projects including the remodelling of St Kilda Junction, the widening of Hoddle Street and then the extensive 1969 Melbourne Transportation Plan changed the face of the city into a car- dominated environment. Australia's financial and mining booms during 1969 and 1970 resulted in establishment of the headquarters of many major companies (BHP Billiton and Rio Tinto, among others) in the city. Nauru's then booming economy resulted in several ambitious investments in Melbourne, such as Nauru House. Melbourne remained Australia's main business and financial centre until the late 1970s, when it began to lose this primacy to Sydney.
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Like many New Zealand secondary schools built in the 1960s, Aorere College was constructed to the Nelson Two-Storey standard plan, distinguished by its two-storey H-shaped classroom blocks. Subsequently, new buildings have been added to accommodate increased student numbers. Developments include a second gymnasium, the Colin Pascoe Gymnasium opened in 2010 and named after the school's second principal, and remodelling of and extension to the hard technology facility in 2018. On-going renovations and upkeep to school buildings and infrastructure underpin the aim to provide a safe and state-of-the-art learning environment for students.
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In 1909, for example, when an enquiry was undertaken about remodelling the Parliamentary Buildings in Macquarie Street it was reported that "the external work, excepting the southern flank, was to be carried out in Sydney sandstone and the main flight of steps in stone obtained from the Purgatory quarry". Many of Sydney's early sandstone buildings remain but many have been demolished. Demolished buildings include: Vickery's Warehouse, Pitt Street; Robert C. Swan & Co warehouse, Pitt Street, Mason Bros stores, Spring Street; Harrison Jones & Devlin warehouse, Macquarie Place; Mutual Life building, George Street; The Union Club, Bligh Street.
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Electric operations commenced on the Berlin–Halle railway in 1978 and on the Roßlau–Falkenberg railway in 1985. In the spring of 1996, extensive remodelling of the station began as part of the German Unity Transport Projects (Verkehrsprojekts Deutsche Einheit): 8.3 (upgrading of the Berlin–Leipzig/Halle line). Three platforms on the Berlin–Halle railway and a 42 m long pedestrian tunnel were completely rebuilt up to 1998. While previously access to the station had only been possible by a road running between the tracks of the lines to Bitterfeld and Dessau, there has since been a direct western exit to the town.
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The Estadio El Arcángel is a multi-use stadium in Córdoba, Spain. It is currently used primarily for football matches and it is the home ground of football club Córdoba CF. Originally the stadium had 15,425 seats and was roughly oval shaped, with an athletics track between the pitch and the stands. Since 2004 the stadium has undergone a remodelling to convert it into a pure football stadium. Three of the four sides of the original ground were demolished and the pitch was moved to be closer to the west stand, removing the gap from the previous athletics track.
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In the early 1930s, Morison joined the Poster Studios, a commercial art business established by architects Harold Krantz, John Oldham and Colin Ednie- Brown. She then undertook the design of the Myola Club in Claremont with Krantz in 1934. During the following years, she worked mainly for Oldham, Boas and Ednie-Brown, where she did the interior detailing of the Adelphi Hotel, the remodelling of the Karrakatta Club in 1936 and the detailing of the Emu Brewery from 1936 to 1938. In the late 1930s, she established herself as an architectural designer and set up her own practice with Heimann (Heinz) Jacobsohn.
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A bus station was created with the remodelling of the station environment around track 1 (the “home” platform) and 2, so today it only has three of its original five through platform tracks. Even the two bay platforms connecting to platform 1 and 2 were removed. Part of the extensive system of freight tracks that connected Südzucker operations in Grünstadt to Worms were acquired for the construction of a park-and-ride area. The two mechanical signal boxes at the northern and southern ends of the station were replaced in 2004 by an electronic interlocking, which is controlled from Neustadt an der Weinstraße.
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Little is known of the Klfs in the myocardium. Klf5 activates the promoter of the hypertrophic agonist platelet derived growth factor (PDGFA) in cardiac fibroblasts a factor previously identified as being upregulated by ET-1, and Klf5+/- transgenic mice heterozygotes (described earlier) exhibited less cardiac fibrosis and hypertrophy when stimulated with angiotensin II compared with controls. Klf5 is itself regulated by the immediate early gene egr-1 in VSMCs, which, if similarly regulated in the cardiomyocyte, places Klf5 potentially in a position to co-ordinate the acute response to external stress and tissue remodelling in the myocardium.
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The statue in 2011 Rhinocéros is a 1878 sculpture by Henri Alfred Jacquemart; a life-sized depiction of a rhinoceros in cast iron. Commissioned to stand outside the Trocadéro Palace for the 1878 Exposition Universelle, it was completed quickly to be ready in time for the opening of the fair. Well received at the time, it was moved in 1935 to allow for the remodelling of the palace and grounds for the 1937 Exposition Internationale des Arts et Techniques dans la Vie Moderne. The sculpture was sited near to the before being acquired by the Musée d'Orsay in 1985.
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Bruce, working with King's master mason Robert Mylne, extended the building with new corner pavilions and a new entrance, and re-planned the interior. Lauderdale continued to employ Bruce, often working closely with Lord Haltoun, Lauderdale's brother, during the 1670s, on his homes at Brunstane near Edinburgh, and Lethington (later renamed Lennoxlove), as well as commissioning a design for new gates at his English property, Ham House, near London, in 1671. At Ham Bruce may have had further involvement with the remodelling works going on there, under the direction of the English architect William Samwell.Gifford (1989), p.
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112 Beyond this was a stair hall of three storeys in height, with arched openings to the entrance saloon at first-floor height, so that the upper part of the entrance saloon could be seen from within it. These arches were filled in as part of Mylne's remodelling, which though it increased the comfort and charm, reduced the spatial drama. The additional wall space in the entrance saloon was designed to display Southwell's recently inherited collection of ancestral portraits, and Thomas Stocking was employed to execute a scheme of plaster framing for these to Mylne's design.Gomme, Jenner and Bryan, p.
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In 537 CE, the Goths besieging Rome tried to use this underground channel as a secret route to invade Rome according to Procopius. After deteriorating with the fall of the Western Roman Empire, the Aqua Virgo was repaired by Pope Adrian I in the 8th century. In 1453, Pope Nicholas V made a complete restoration and extensive remodelling from its source to its terminus points between the Pincio and the Quirinale and within Campo Marzio and consecrated it Acqua Vergine. This also led the water to the Trevi Fountain and the fountains of Piazza del Popolo, which it still serves today.
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The Lady Chapel was built later that century at the east end of the south aisle and was linked to the holders of the manor, at that time the Brounckers; the chapel was refitted in 1909. Extensive remodelling in 1845 by T.H. Wyatt included moving the four-stage 16th-century tower from the crossing to the west end, and adding a vestry and chapel on the north side. In 1881 the chancel was restored. The fine carved limestone reredos of 1894 is by C.E. Ponting, and the carved oak chancel screen is of the same date.
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The 4th century fort constituted a drastic remodelling of the 3rd-century one, while retaining the same orientation as its predecessor. The only surviving ruined wall of the 4th century fort, identified as part of the fort in 1950, is now known as Wery Wall. The evidence suggests that the fort remained active up to the end of Roman occupation of Britain in the early 5th century, being used as an early Saxon shore fort. The Roman baths, of the second fort, were discovered in 1812 and can be seen near the junction of Bridge Lane and Church Street.
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She acted as Regent of Savoy from 1675 in the name of her son Victor Amadeus II, who was her husband's successor. Her regency officially ended in 1680, but she maintained power until her son banished her from further influence in the state in 1684. She left a considerable architectural legacy in Turin, and was responsible for the remodelling of the Palazzo Madama, which was her private residence. At the time of her death she was the mother of the King of Sardinia as well as great grandmother of two other kings, Louis I of Spain and Louis XV of France.
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The first station at Abergavenny Junction lasted only until 20 June 1870 when it was relocated further north. The L&NWR; had sought to improve access to the Merthyr branch by remodelling the junction which became a north-facing triangular junction with the provision of a north-to-east spur from a new Abergavenny Junction station. This avoided the need for reversal required by the old junction which faced the GWR's Monmouth Road station. The east-to-south arm of the junction, which had been the original connection, was rarely used for passenger services, but was useful for turning engines.
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Although called Old Beaupre Castle the structure is seen as a fortified manor house. The original house was an L-shaped building, now located within the inner courtyard, built circa 1300 and from this period until the 18th century it was owned by the Basset family. During the 16th century intensive remodelling was undertaken, started by Sir Rice Mansel, continued by William Basset and completed by William's son, Richard. This additional work added the impressive outer gatehouse, completed in 1586 and a three-storeyed Renaissance porch, completed 1600, along with the buildings around the middle court.
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The first step of the project will be to open the "Tren del Valle" that will connect cities of Neuquén (of the homonymous province) and Cipolletti in Río Negro Province. Rolling stock used will be provided by local company Materfer, that was committed to build 20 CMM 400-2 railcars to run on the line. There is no time limit for the reopening. Works for the reopening include repair of the bridge that crosses the river and the remodelling of Neuquén station, apart of the installation of six warning devices on six level crossings along the route.
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Despite modernization in the 1960s the interior has maintained some of its original features, including marble wainscoting and some woodwork. The post office was built in 1940 to a design by Leon Pernice, an architect based in West Springfield. It was built at a time when the federal government was emphasizing simplified styles whose designs could be approved and executed rapidly, providing jobs to the community. The building underwent a substantial remodelling and enlargement in 1968, when a large ell was added to its rear, and glass-and-aluminum partitions and fluorescent lighting were added to its lobby area.
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The 1950s wing's rooms, from the south, included: dressmaking, with a staff room and fitting room to the north; then another fitting room, for a second dressmaking room to the north.DPW Plan A50/353, "Bundaberg High & Interme [sic] School, domestic science building, additions and remodelling", July 1955Project Services, 'Bundaberg State High School'Bundaberg State High School: 75th Anniversary Celebrations, 1912-1987, p.11 (extension completed 1956). The staff room was removed from west end of the original verandah. Workshop No.2 (Block M in 2017), for Motor Engineering, was planned in 1955, south of Block R, but was not built until 1958-9.
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By 1842 the heralds were reconciled with their location and once again commissioned Abraham to build a new octagonal-shaped Record Room on the site of the old Sugar House. In 1861 a proposal was made to construct a road from Blackfriars to the Mansion House; this would have resulted in the complete demolition of the College. However, protests from the heralds resulted in only parts of the south east and south west wings being sliced off, requiring extensive remodelling. The College was now a three-sided building with an open courtyard facing the New Queen Victoria Street laid out in 1866.
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Abdominal ultrasound can be used to visualize the insertion site of the umbilical cord. Overall, visualization is most successful in the second trimester, however routine ultrasound examination in the second trimester may not detect velamentous cord insertion if the condition develops after the remodelling of the placenta as gestation advances. Visualization becomes increasingly difficult in the third trimester as the fetus may obscure the insertion site. The umbilical cord and its insertion site may be obscured by the fetus, such as in posterior placenta or in low-lying placenta, or may be difficult to visualise due to conditions such as maternal obesity.
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The crown of the west entrance has been lowered to admit of the insertion of a large 'churchwarden' window and the external jambs have been replaced with plain cut stone. 250px It is probable that the Dillingtons were responsible for the churchwarden creations in the north transept, and the west wall, and the final remodelling of the tower. There are two small chapels succeeding the two transepts. Over the gable of the south transeptal chapel, a "singular SAINTS or SANCTE BELL turret" has been erected (the bell was first struck when the image of the Saint was deified).
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Double decker carriages made by Emfer for TBA. TBA was established in 1995 after the Carlos Menem's administration privatised all the railway network, giving the company concession to operate the metropolitan Mitre and Sarmiento railway lines by Decree N° 730/95. The company took over both lines on 27 May. During the first two years of concession, TBA met the requirements specified on the contract, about the frequency of the service, with an average of 98%. By February 1999 the consortium had invested US$200 million, which included the reconstruction of 220 Toshiba carriages and the remodelling of 13 stations and workshops.
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This property is observed in histone fold-domain containing transcription factors (fork head box (FOX) and NF-Y) and other transcription factors that use zinc finger(s) for DNA binding (Groucho TLE, Gal4, and GATA). The eukaryotic cell condenses its genome into tightly packed chromatin and nucleosomes. This ability saves space in the nucleus for only actively transcribed genes and hides unnecessary or detrimental genes from being transcribed. Access to these condensed regions is done by chromatin remodelling by either balancing histone modifications or directly with pioneer factors that can loosen the chromatin themselves or as a flag recruiting other factors.
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In September 1996, Your Channel Television Inc., a company majority owned by Atlantis Communications with minority partner E. W. Scripps Company, was granted a television broadcasting licence by the Canadian Radio-television and Telecommunications Commission (CRTC) for a channel called HGTV-TV Canada, described at the time as broadcasting "programming that presents practical, hands-on advice and instruction about homes and gardens. The programming will revolve around five key themes: building and remodelling, decorating and interior design, gardening and landscaping, crafts and hobbies and special interests."Decision CRTC 96-607 CRTC 1996-09-04 HGTV Canada logo used from 1997 to 2012.
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Chakeres Theatres operated the Fairborn Theatre from 1948 until the early 1970s, when it was temporarily closed to be remodelled into a two-screen operation. Following remodelling, the theater ran until January 2000, when Chakeres ceased operating it; the company retained ownership until 2002, when it donated the building to a Fairborn arts organization. Soon afterward, more than ten years of renovation began; carried on largely by volunteers with a small budget, renovations have included ridding the building of asbestos, roof maintenance, and removing the wall separating the two theater rooms to restore them to their original one- room format.Crowe, Amanda.
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During 1959, county officials spent large sums of money on an extensive remodelling project, followed by another project in 1963; the resulting two-story building features a main entrance inside an ell, a few tall rectangular windows on all sides, and a flat roof. Although the current courthouse is technically the same building as the one constructed in 1881, absolutely nothing remains of the original construction, and the courthouse's record in the Illinois Historic Sites Survey Inventory refers to it strictly as "2 story ugly brick (recent)" without any additional comment.Urbane, Christine. "Illinois Historic Sites Survey Inventory: Wabash County Court House Site".
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The line is strategically important, as electrification and junction improvements would mean that High Speed 1 trains could travel directly from to Hastings. In 2015, Amber Rudd, Member of Parliament for Hastings, campaigned for electrification works to start within the next two years. The aim is to reduce times to London from Hastings to 68 minutes, and from Rye to under an hour. This would require remodelling Ashford International station so the existing Marshlink line could connect to HS1, installing power systems, and adding a grade-separated diversion from Rye to the west, all in addition to requiring new trains.
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It was suppressed in 1825. At the same time a Catholic Relief Bill passed the House of Commons, but was thrown out in the Lords, and all that Ireland got from Parliament was the act suppressing the Association, or the Algerine Act, as it was often called. The Catholic Association, changing its name into the New Catholic Association and remodelling its constitution, continued its work. It was to build churches, obtain cemeteries, defend Catholic interests, take a census of the different religions, and for these the "New Catholic Rent" was subscribed, and meetings were held in Dublin, where Catholic grievances were discussed.
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The town with Citadel in 1786. Also shown is the first town dock on the line of the north walls, and the western walls and Bush Dike. (survey by A. Bower) The Citadel was a result of extensive remodelling and civil engineering work on the former Hull Castle and South Blockhouse (1680s); a triangular artillery fort was created at the western bank of the Hull at its confluence with the Humber. Beckmann estimated the cost of the improvements at over £74,000 and eventually over £100,000 was expended on the works, was acquired by the Crown for the expanded work.
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Once the remodelling is totally finished, the stadium will be able to host an attendance of 35,000.Chacarita anuncia inauguración del nuevo estadio The Governor of Buenos Aires Province, Daniel Scioli, was the most notable presence in the event and was the person who cut the ribbon to declare the stadium officially reopened. This act was made in front of the Isaac López stand, named as a tribute to the legendary goalkeeper who played the most games for Chacarita (343 matches, from 1937 to 1952).Aniversario del fallecimiento de Isaac López Finally, a colorful set of fireworks closed the ceremony in Villa Maipú.
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Hagia Sophia of Nicaea (İznik) in 1962 (photo by Paolo Monti) A timber-roofed basilica with a central nave and side aisles, it was built shortly after 1065, but extensively remodelled after its conversion into a mosque. Before the remodelling it had two rows of triple arcades on columns that carried a clerestory wall with five windows.Richard Krautheimer, Early Christian and Byzantine Architecture, 4th edition, 1986, p365. It was converted to a mosque after the fall of the city to the Ottoman Turks in 1337, and functioned as such until it was converted into a museum in 1935.
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On 24 June 1858, Parthenope married her sister's rejected suitor, Harry Verney, 2nd Baronet, MP for Buckingham, a supporter of liberal causes and possessor of the family seat, Claydon House. After marriage, the new Lady Verney was able to develop her own talents independent of the shadow of her more famous sister; she soon turned Claydon House into a salon for interesting people, and was responsible for extensively remodelling and restoring Claydon House. She preserved and catalogued the family papers, and began scholarly research into the Verney family. She began writing stories and articles for Fraser's Magazine, Cornhill Magazine, and Macmillan's Magazine.
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The Morning Post dated 28 December 1835, Page 3 The 2nd Marquess continued with the improvements to the castle by the remodelling of William Adam's West Wing, which was enlarged and refaced to match the main block. This time, the architect was James Gillespie Graham, with interiors designed by A. W. N. Pugin. The ceilings of the West Wing are described by Historic Scotland as the "finest of their period in the UK". It took an Italian painter nearly ten years to paint the ceilings with the various coats of arms of the Breadalbane family and their flags.
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Mills Observatory, 1935 James MacLellan Brown (21 September 1886 – 25 December 1967) was a Scottish architect who was the city planner of Dundee, Scotland, known for remodelling of Sir John James Burnet's designs (1931) and designing the Mills Observatory (1935). Brown was born in 1886, the son of David Brown, a weaver, and Janet MacLellan Brown. Brown was the assistant to the City Architect, James Thomson, who had originally planned an immense Beaux-Arts style Civic Centre covering the centre of Dundee. When the First World War intervened, his plans were scaled down and he retired in 1924.
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They demolished the gallery and Hall of the Kings, constructed the towers of the eastern dormitory, the rose window of the upper choir and substituted the pyramid-shaped roof of the bell tower with the mitre-shaped design. The remodelling was delayed by the 1878 collapse of the central dormitory. After 1884, Raymundo Valladas began to contribute, initiating in 1886 the restoration of the cloister and the Sala do Capítulo, including construction of the vaulted ceiling. The tomb of Alexandre Herculano, designed by Eduardo Augusto da Silva, was placed in the Sala do Capítulo in 1888.
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During the 15th and the early 16th centuries, extensive construction work was carried out, including a chapel for Isabeau de la Tour du Pin at the end of the 15th century. The Duke of Sully took ownership of the dilapidated castle in 1606 and embarked on a programme of improvements which included remodelling the residence, strengthening the fortifications, digging moats and creating a garden. Between 1621 and 1652, the architect Jean Sarrazin completed fortifications for Henri II de Condé and his son Louis II le Grand Condé. The castle was besieged for eleven months to September 1652; twenty starving survivors surrendered with honour.
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Following the Williamite confiscations, which saw the Flemings dispossessed, the present form of the Castle and the village centre were re-cast and in the latter case, laid out as a model British village by the Ulster plantation family of the Conynghams, in what is considered a typical example of 18th- century town planning. As part of this remodelling, today in the centre of the village stand four nearly identical Georgian houses. The four houses stand at the intersection of the two main streets in the village. While the four faces of the houses and the four open streets form an octagon.
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Little Pheasant Castle Fasanenschlösschen around 1790 with miniature mock battles at sea Lighthouse with jetty Shortly after the remodelling of Moritzburg Castle as the country seat of August the Strong, a single-story pavilion was built just away by the architect Johann Christoph Knöffel. The pavilion's foundation was later used for the Chinese-style Little Pheasant Castle (Fasanenschlösschen) in 1770. Elector Frederick Augustus III of Saxony had the pavilion built in the middle of the gardens. Johann Daniel Schade who had been the architect in charge of the royal building projects, received the commission for the Rococo design.
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The sermon was preached by Rev. Leon Adams, incumbent at Combermere and scoutmaster of the Combermere troop who thanked the St. Matthew's Group for its good deed. "All scouts", he said, "were members of the 'Good Deeders Club' and must show a good deed to the world at this time in remodelling it into the new order for which men were living and dying for today". Rev. Eric Osborne, assistant at St. Matthew's, dedicated the flag and presented it to King's Scout Fred Kempster who in turn presented it to the scoutmaster of the new Combermere troop.
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In March 1660, Sir William Davenant contracted to lease Lisle's Tennis Court in order to renovate it into a theatre, and he bought adjoining land to expand the building into the garden area. Killigrew's theatre on Vere Street (Gibbon's Tennis Court) opened first, in November 1660. Davenant apparently spent more time in his remodelling: Lincoln's Inn Fields opened on 28 June 1661, with the first "moveable" or "changeable" scenery used on the British public stage, and the first proscenium arch. Wings or shutters ran in grooves and could be smoothly and mechanically changed between or even within acts.
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Westcott Lodge Westcott Lodge is a Grade II listed house in Lower Mall, Hammersmith, London. It was originally St Paul's Vicarage, and built in 1746, with some later remodelling, and restoration after damage during World War II. In 1962, it was the first home of the Hammersmith Chess Club, which met there until 1970, when it had grown too large, and moved to St Paul's Church Hall. The first president was the eccentric Lady Herbert, wife of A. P. Herbert from 1966. 1968 saw the British champion, Dr. Jonathan Penrose, play a simultaneous display at the club, winning 17 games and drawing two.
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Southern Railway 'N-15/King Arthur' at Gilberdyke station with a charter train prior to the station remodelling (1982) The station is operated by Northern. The station is served hourly in each direction on weekdays by local trains between Hull and Doncaster and by the to Hull via service, along with a limited service (one departure per day) to and Manchester Piccadilly operated by TransPennine Express. This is the 1K04 service leaving Hull at 05:06 Monday to Saturday calling at Gilberdyke at 05:25 in the December 2019 timetable. On Sundays there is an hourly service to Hull and Doncaster.
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Hibbert, pp. 503–504; St Aubyn, p. 624 Victoria Memorial in front of Buckingham Palace was erected as part of the remodelling of the façade of the Palace a decade after her death. Victoria was physically unprepossessing—she was stout, dowdy and only about five feet tall—but she succeeded in projecting a grand image.Hibbert, pp. 61–62; Longford, pp. 89, 253; St Aubyn, pp. 48, 63–64 She experienced unpopularity during the first years of her widowhood, but was well liked during the 1880s and 1890s, when she embodied the empire as a benevolent matriarchal figure.
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CPAT was established in 1975 along with three other Welsh Archaeological Trusts. It emerged from the ‘Rescue Archaeology Group’ (RAG) which was set up in 1970 by Chris Musson, who became the first Chief Executive of CPAT. The Trust undertook pioneering work on prehistoric sites in mid-Wales, beginning with the excavation of the Breidden hillfort (Powys) which was being destroyed by quarrying. This was followed by the excavation of a late Iron Age hillslope enclosure at Collfryn (Powys), which found evidence for intensive occupation and remodelling of the site, including round-houses and ‘four-poster’ structures that were probably granaries.
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The purpose of this proposal is to provide a flyover for this line to clear all the other lines north of Hitchin station on the main route (direction of Stevenage). Additionally, the junction of the merging (southbound) line from Cambridge would be remodelled to provide access to the fast line before reaching Hitchin station. Partial remodelling of Peterborough and Doncaster layouts There would be a requirement to alter the arrangements at both ends to facilitate the use of the alternative route. At Peterborough this will be combined with arrangements to provide better accommodation for other passenger services off the ECML.
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This analysis only helped to confirm the decision of the Administrator General of the district of Viana do Castelo in 1838: a majority of the Misericórdias were badly administrated, resulting in the loss of funds, that was treated by their administration with little zeal. In 1839, the same administrator sent a financial commissioner to reform the bureaucracy, examine the errors and clean up the sloppiness in the Misericórdia of Valadares. In 1848, a tender was issued to many of the masons for the remodelling of the exterior walls of the church. In 1855, the municipality of Valadares was extinguished.
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