CBD helps to calm and relax you if you're overstimulated.
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I likened myself to an overstimulated, slightly warped Manic Pixie Dream Girl.
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So now instead of being overstimulated and awake, I'm bored and awake.
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The positive impulses created by the food can help when you feel overstimulated.
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We're overwhelmed, and overstimulated, and over adapting way more rapidly than we can.
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People across the political spectrum could be excused for feeling a bit … overstimulated.
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"This thing happens when you're like grossly overstimulated, your memory changes," she said.
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"When I feel overstimulated by the world, I lean on my family," she says.
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But if you leave feeling simultaneously exhausted, overstimulated, and strangely bored, you aren't alone.
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Any time you're consuming cannabis, your body's cannabinoid receptors are being activated and, essentially, overstimulated.
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I get that we are overstimulated, but stop scrolling and show someone you care. 2.
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The overstimulated mice take more risks and find it harder to learn and stay attentive.
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Instead, as a consummately overstimulated person, he dreads a world where devices start sending you odors.
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She warned me to avoid hot peppers and pickles, in order to spare my overstimulated tongue.
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Is this overstuffed rendering of an overstimulated culture what they call the fallacy of imitative form?
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The overstimulated American economy will run off the cliff on its own momentum, Mr. Bernanke fears.
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First, people were overstimulated by other forms of entertainment, and lost the ability to concentrate on books.
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Maybe I'll always want a "bigger, brighter" TV. Maybe I want to be perpetually overstimulated by entertainment technology.
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But in an overstimulated economy, you get soaring prices and may need higher rates to slow things down.
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They each recall the atmosphere of hysteria, the heavy, overstimulated mood that clung to everything surrounding the case.
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In this overstimulated world full of screens and social networks, it's necessary to cultivate our minds with deeper things.
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While I felt somewhat aroused, I was too overstimulated to focus intently on what was happening in my jorts.
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Sitting with other reporters and Alibaba communications staffers, I was immediately overstimulated, even without the ability to shop online.
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During the musical numbers, which feel relentless, the ensemble comes off as a troupe of overstimulated mimes playing charades.
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Almost 20 years after Messages to the Public, this new series could not be more relevant to our overstimulated society.
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Ross, a 22-year-old in Las Vegas, told me that he gets overstimulated when being intimate with his boyfriend.
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But will today's overstimulated 2- to 5-year-olds find a springy dog and her human sidekick a little basic?
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All these forces tried to get our collective attention, but collective attention is a rare commodity in our overstimulated environment.
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How can a regular overstimulated and underactualized person survive in this reality show that has so clearly jumped the shark?
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"They are overstimulated and don't have enough mental downtime; even three minutes of mindful meditation twice a day can help."
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This definitely does sag in the middle and I'm sorry but in my defense I am enormously overstimulated at the minute.
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If you're feeling overstimulated by materialistic concerns, you can lean into your immaterial, priceless treasures like sex, art, friendship, and community.
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But will today's overstimulated preschooler find a springy dog and her human sidekick a little basic in a noisier digital age?
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In other words, neurasthenia was thought to be a disease of nerves overstimulated by the pressures of work, leading to fatigue.
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"WE, THE OVERSTIMULATED CHILDREN OF THE NIGHTLIFE, ARE BEGINNING TO FEEL THE WAVE DISTORTIONS FROM GENERATIONS OF SUBTLE STRUCTURAL MANIPULATIONS," he wrote.
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When given the option to dose themselves with cocaine, the overstimulated mice were much more prone to addiction than the control group.
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There have been some exceptions—I had trouble sleeping after reading the original Amityville Horror novel—but frankly, I've grown up overstimulated.
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Be careful not to put younger babies in the outward-facing position for very long because they can get overstimulated very easily.
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After about five minutes, our vaginas were tired and overstimulated; both of our minds had decided that it wasn't going to happen.
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Spending too much time around other people can leave you overstimulated and without the time you need to set your own goals.
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We constantly try to feed our mind new hits of distraction when really we should be lowering how overstimulated our mind is.
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I'm going through IVF and recently had my egg retrieval, but I ended up having to freeze all the eggs due to being overstimulated.
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We're constantly overstimulated, and online languages are becoming even more fractured by the day, divided along the same lines as our pop culture consumption.
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If he tried to watch a movie, he'd fall asleep within the first five minutes, as if his overstimulated brain were powering itself down.
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"For a person who is easily overstimulated, like an autistic individual can be, the commotion of an airport can elicit tremendous anxiety," she said.
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Jorien has returned from a shopping trip with a type of fruit she was unfamiliar with; she bought it while feeling overstimulated in the store.
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The mental cues that the day was done and it was time to relax have helped reinforce a balance that helps me from getting overstimulated.
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"First, I always assess which senses are being overstimulated while eating," says Ilse van Heumen, a dietician who specializes in food issues among people with autism.
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The back-carry position is also much more appropriate for her now that she has full head control and she's not as prone to getting overstimulated.
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The apparatus has been designed to find out what happens to the rodents' brains when they are overstimulated by media during a critical window for their development.
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If you can think straight while being bombarded with Ryan Trecartin's barrage of overstimulated narrative, it's possible to see the politics of the post-post-internet emerging.
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This presidential campaign is more than a shitshow, an authoritarian fit, or a clash between the identity politics of socially isolated white people and socially overstimulated snake people.
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"It's hard not to have sympathy for somebody who experienced that level of childhood trauma: An overstimulated medulla looks for and perceives danger everywhere," he told Indie Wire.
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With both devices, I felt exhausted and overstimulated after 20-minute sessions — virtual reality feels like media designed to be consumed in small doses, not hours at a time.
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Click here to view original GIFWe are all overstimulated automatons making our way through the day, just moving from one screen to the next in a sleep-deprived stupor.
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The most important reason they don't do so right now is because they're afraid of being overstimulated: What if they don't like the food or if makes them vomit?
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" He compared the mood here with Shenzhen, where "people are constantly overstimulated, staring at their phones on the subway, craning their necks downward to watch some imported soap opera.
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Overstimulated by the cafeteria and the food, Aza goes into a "thought spiral," stream-of-conscious concerns reminiscent of Mark Haddon's The Curious Incident of the Dog in the Night-time.
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"The little dudes at our wedding were selected for being especially social, there were volunteers making sure they were handled safely and not overstimulated, and they left after about an hour," they said.
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A cat who bites when being petted likely doesn't hate you—he would probably not let you pet him in the first place, and was likely touched in the wrong place or overstimulated.
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"The UK economy appears to be solid enough on key economic criteria, and even 'overstimulated' by others, such that a moderate reduction in the substantial amount of monetary stimulus ... makes sense," Forbes said.
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Roger Ailes, one-time boss of Fox News, gets a cameo in the film, and it caters to the overstimulated mediaverse he helped to create, in which short attention spans require constant jolts.
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They were circling around a kind of overstimulated numbness, considering everything from what it meant to call something "interesting"—a hedge against actual judgment—to the relationship between economic anxiety and mental health.
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Although Sepah says he's created "the antidote to our overstimulated age," in reality he seems to have created something more like a stopgap measure, one prone to being misinterpreted in harshly ascetic ways.
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Because the Great Inflation was seen as partly resulting from mid-22019th Century Keynesian economic policies that had overstimulated spending, Volcker began considering alternative ideas being promoted by monetarists such as Milton Friedman.
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After a couple of singles indulging his more chart-ready impulses, your favorite masked marauder Marshmello's back with another track that feels as wonderfully oversaturated and overstimulated as a colorized black-and-white film.
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These molecules, in turn, may disrupt the amygdala, a region near the base of our brain that contributes to anxious feelings when overstimulated, according to a 2016 study published in the Journal of Neuroscience.
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Endocannabinoids are the only neurotransmitters that engage in such 'retrograde signaling,' a form of intracellular communication that inhibits immune response, reduces inflammation, relaxes musculature, lowers blood pressure, dilates bronchial passages, and normalizes overstimulated nerves.
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With too much of modern day-to-day life spent being chronically online, overstimulated, and filled with anxiety, the good-natured humor in Joe Pera Talks With You provides a brief but deserved respite.
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Unlike Netflix with its hated "are you still watching" (yes, yes I am) popover, YouTube's autoplay function will theoretically play forever, making it something of a godsend for the chronically overstimulated trying to get some shuteye.
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I felt alternatively overstimulated or oppressively lonely, going between parties where I had nothing to say because my life was chaos and days of minimal human contact that only revolved around different ways to drink coffee.
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So even though the boy is slow to talk, uncommonly afraid of new situations and flaps his arms when overstimulated, she chooses to think that his behavior is normal and will go away on its own.
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Employees at Sesame Place, in Langhorne, Pa., for example, recently completed training on autism sensitivity and awareness, and the park has two quiet rooms with adjustable lighting for those who are getting overstimulated and need some downtime.
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They also tapped painter and VICE contributor Theresa Chromati to turn her paintings of black women with mouths for vaginas into an animated woman that takes her overstimulated heart to a zen river comically accompanied by her talking vagina.
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" When I ask Klemanski about my compression pants specifically, he says that it's actually along the same lines as using compression vests for kids who are feeling overstimulated from symptoms of ADHD—"using tight clothing to make them feel swaddled.
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The fidget spinner is nothing but nervous energy rendered in plastic and steel, a perfect metaphor for the overscheduled, overstimulated children of today as they search for a way to unplug between jujitsu lessons, clarinet practice and Advanced Placement tutoring.
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Even if the baby isn't directly looking at the screen -- for example, if a mother is nursing her child on the couch while watching TV -- the baby can be overstimulated by the lights and sounds, which may cause distress and sleep problems.
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It was a welcome respite from the chaos and constant change built into childhood, and today feels almost otherworldly — and necessary — considering how overstimulated most of us are, juggling smartphones and laptops while watching TV, toggling between two gears: sleep and go-go-go.
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Surrounded by potential mates, his libido is a little overstimulated (or understimulated, I suppose, depending on his lifestyle.) In the same segment, Viall cops to farting on camera — again, obvious — and having hooked up with another member of Bachelor nation outside of any show.
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As New York Times reporter C.J Hughes notes, visitors are already overstimulated by the barrage of stores and flashing signs in the area, not to mention that they may be disenchanted by recent endeavors that failed to stay afloat longterm, such as The N.F.L. Experience Times Square.
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Instead, Bailey's overarching thesis is that tech companies are really, really good at getting you to stop whatever most important thing you're doing and spend time on whatever dumb app or website they're making gargantuan sums of money on, and therefore our brains are constantly overstimulated.
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And he didn't produce brilliant work in spite of the more conventional folks surrounding him in Illinois; as his essays and books like "The Pale King" reveal, he was inspired by the Midwest's sincerity to go beyond America's cultural snark for truth about its contemporary life, which he found rushed, overstimulated and lonely.
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For example, a blog post about having a designated place for your child to do schoolwork leads to half a dozen adorable wood desks but also includes a few words from a psychologist — "Neuroimaging clearly shows that individuals" with attention deficit disorder or attention deficit hyperactivity disorder "have different pathways of communication in the brain when compared with 'typical' individuals" — and an explication of the importance of modeling organization to children with A.D.D. or A.D.H.D. The swings on the site are just swings, but the text explains how they can calm a child who's overstimulated.
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However, they may become overstimulated and upset if they hear something for which they are unprepared.
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The subsequent lack of acetylcholine hydrolysis causes accumulation of acetylcholine at cholinergic synapses. This in turn causes cholinergic receptors to become overstimulated.
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Gonadotropes appear basophilic in histological preparations. Gonadotropes have insulin receptors, which can be overstimulated by too high insulin levels. This may lead to infertility as hormone release levels are disrupted. Gonadotropes are feedback inhibited by specific hormones, including estradiol.
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In The Rolling Stone Album Guide, Sheffield describes it as "the music of an overstimulated mind in an exhausted body", showcasing Bowie as he "sashays through some serious emotional wreckage". Susie Goldring of BBC Music praised the album, calling it "ambitious" and complimenting Bowie's artistic growth, having turned 30 on its release.
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Some of the nerve agents attack and destroy acetylcholinesterase by phosphorylation, so the action of acetylcholine becomes excessive and prolonged. Pralidoxime (2-PAM) can be effective against organophosphate poisoning because it can re-cleave this phosphorylation. Atropine can be used to reduce the effect of the poisoning by blocking muscarinic acetylcholine receptors, which would otherwise be overstimulated, by excessive acetylcholine accumulation.
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The adrenal cortex is hyperplastic and overstimulated, with no impairment of the mineralocorticoid pathway. Consequently, levels of DOC, corticosterone, and 18-hydroxycorticosterone are elevated. Although these precursors of aldosterone are weaker mineralocorticoids, the extreme elevations usually provide enough volume expansion, blood pressure elevation, and potassium depletion to suppress renin and aldosterone production. Some persons with 17α-hydroxylase deficiency develop hypertension in infancy, and nearly 90% do so by late childhood.
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The qualitative division of the activity is completely different from the two quantitative divisions. It occurs when color is presented to the eye. Schopenhauer described the way in which various points or places on the retina become fatigued from being overstimulated. After staring at a black figure on a white background, the overactive and excited retinal points become exhausted and do not react to stimulation when the eye finally looks away.
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To keep them subservient, they must not drink alcohol, miss the medication, or be overstimulated, or the women will become hostile and potentially violent. Kaye is discovered and narrowly escapes, and the men set out to track her down. Kaye shows up at Megan's house, throws out her pills and compels her to down some vodka. At first, Megan attempts to stab Kaye and manically clean the house.
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In order to explore the influences of the hypothalamus as a drive on the four Fs, researchers lesioned the lateral areas of the hypothalamus of rats. This resulted in a reduction in the interest of eating (feeding). If these animals were not fed or cared for, they starved to death, even when enough food was present around them. The influence of the hypothalamus is also clear when researchers overstimulated the hypothalamus.
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Lisa considers asking Dr. Hibbert for help, but realizes that would ruin her reputation as a babysitter. Instead she takes Bart to Dr. Nick Riviera's clinic in a wheelbarrow, bringing Maggie along in a pet carrier because the coffee ice cream has overstimulated her. Lisa is unable to see the doctor due to a long queue in the waiting room. Frantic, Lisa tries to wheel Bart and Maggie to the hospital.
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Transmarginal Inhibition Additional research on these phases was done by William Sargant in his work on shell-shocked servicemen. An organism can progress through these stages by increased stimulation, random negative stimulation, reversing positive and negative stimulation, or physically debilitating the organism. As observed by Pavlov, tolerance of stimulation varies greatly between individuals. Highly sensitive persons may be overstimulated by the loud volumes in a movie theater or the background confusion of a large social gathering.
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Hedonic adaptation can occur in a variety of ways. Generally, the process involves cognitive changes, such as shifting values, goals, attention and interpretation of a situation. Further, neurochemical processes desensitize overstimulated hedonic pathways in the brain, which possibly prevents persistently high levels of intense positive or negative feelings. The process of adaptation can also occur through the tendency of humans to construct elaborate rationales for considering themselves deprived through a process social theorist Gregg Easterbrook calls "abundance denial".
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Increased insulin secretion leads to hyperinsulinemia, but blood glucose levels remain within their normal range due to the decreased efficacy of insulin signaling. However, the beta cells can become overworked and exhausted from being overstimulated, leading to a 50% reduction in function along with a 40% decrease in beta-cell volume. At this point, not enough insulin can be produced and secreted to keep blood glucose levels within their normal range, causing overt type 2 diabetes.
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Northrup also suggested his frequent collaborator Ron Hippe as a keyboard player. "Frederick Babyshirt" and "Ronald Babyshoes" were the Caspar Babypants live band from May 2009 to April 2012. Both Northup and Hippe appear on some of his recordings but since April 2012 Caspar Babypants has exclusively performed solo. The reasons for the change were to include more improvisation in the show and to reduce the sound levels so that very young children and newborns could continue to attend without being overstimulated.
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The Anatolian is also a bold, confident dog that does not become overstimulated easily. It is generally curious but aloof with guests, not an outgoing dog that wants to make friends with everyone and can dislike strangers who are too forward or excited. It is calm and observant of its surroundings and may not go looking for trouble, but may not back down if challenged. An Anatolian that has been agitated or ill-trained may become aggressive and not easily controlled or restrained on command.
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Warren "Grizz" Griswold (Grizz Chapman) is another member of Tracy's entourage. A recurring character during the first two seasons, he is credited as a series regular in seasons three and four. Grizz is the most physically imposing member of Tracy's entourage and the cast; referencing their long friendship in "Argus", Tracy tells him "I've known you since you were six feet tall!" Within the entourage, Grizz is charged with "sitting on" Tracy when he is overstimulated, in addition to a very fluid list of other responsibilities.
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Babies and toddlers will play with their genitals in much the same way as they play with their ears or toes. If such play becomes all-consuming, it may be necessary to look for an underlying cause of this, such as the child being tense and in need of comfort, or that others may be overreacting and thus reinforcing the habit. It could be caused by a low-grade urinary tract or yeast infection. The child may be overstimulated and in need of soothing, or understimulated and bored.
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Although the cause of klazomania is unknown, it is considered to be associated with encephalitis lethargica; a 2006 journal review by Jankovic and Mejia attributes klazomania to tourettism (tics not due to Tourette syndrome), widely seen after the encephalitic lethargica pandemic of 1916 to 1927. Wohlfart (1961) hypothesized that klazomania is caused by an irritating lesion in the mesencephalon and a malfunction in the control of the motor circuit from the substantia nigra in the mesencephalon to the globus pallidus in the striatum (mesostraital pathway). This circuit becomes overstimulated during a mesencephalic "fit". In a 1996 report of one case, Bates et al.
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Transneuronal degeneration is the death of neurons resulting from the disruption of input from or output to other nearby neurons. It is an active excitotoxic process when a neuron is overstimulated by a neurotransmitter (most commonly glutamate) causing the dysfunction of that neuron (either damaging it or killing it) which drives neighboring neurons into metabolic deficit, resulting in rapid, widespread loss of neurons. This can be either anterograde or retrograde, indicating the direction of the degeneration relative to the original site of damage (see types). There are varying causes for transneuronal degeneration such as brain lesions, disconnection syndromes, respiratory chain deficient neuron interaction, and lobectomies.
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" The Boston Globes Peter Keough criticized the film, "It's not so much untold as rewritten—if not by J. R. R. Tolkien than by some clever 12-year-old overstimulated by The Lord of the Rings." Film critic Ben Kenigsberg reviewed the film for The New York Times, "The movie is the latest multiplex filler to co-opt a classic tale only to drown it in computer-generated murk. Even the title has the ring of something created by committee." James Berardinelli reviewed for website ReelViews, "A generic vampire tale in the Underworld vein that comes closer to the infamous Van Helsing than a memorable re- interpretation of a legendary monster.
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Sam, states Heyne, despises his bourgeois life, but surrenders to it, perhaps making him the object of Mailer's derision. "The Man Who Studied Yoga" is perhaps Mailer's sole excursion into middle-class normalcy: Sam and Eleanor seem to have a successful, if somewhat boring, suburban life, but it is soon interrupted by watching a pornographic movie with friends. Overstimulated by the movie, Sam dreams of Louis XV's garden of virgins called the Deer Park which becomes the title of Mailer's third novel about Hollywood. In fact, Mailer writes in his journal that finishing "Yoga" gave him the necessary drive and confidence to write The Deer Park.
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This commonly occurs with G protein coupled receptors (see Protein kinase C#Function); cytokine and other non-G protein couple receptor types may also become heterologously desensitized by agents that activate protein kinase C but, perhaps more commonly, by agents that activate other protein kinases such as mitogen-activated protein kinase (p38 MAP kinase). Heterologous desensitization may occur in cells that are grossly overstimulated for prolonged times by a certain agents. Receptor desensitization, whether heterologous or homologous, may contribute to human pathology. For example, excessive desensitization due to the overexpression of GRK2 leads to the loss of β-adrenergic receptor signaling in hearts (see Adrenergic receptor#β receptors].
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PopMatters placed it at #5 of "The Best Metal Albums of 2007". Reason magazine chose it as one of the "Best Albums of 2007" though they were more severe than other critics about the lyrical content saying that "Lyrically, it's ridiculous" and "if your grandma was theming a prog rock album, it'd come out something like this". Dan LeRoy from Alternative Press announced it "as heavy as P-Tree have ever been" but "wistfully, sprawlingly melodic as well-sometimes in the same tune" and concluded that "if Wilson's vision of today's kids as overmedicated, overstimulated robots seems like a blatant appeal to the over-30 crowd, it's still worth setting the Xbox aside to listen".
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Reagan launched his campaign with an indictment of a federal government that he believed had "overspent, overstimulated, and overregulated." After receiving the Republican nomination, Reagan selected one of his opponents from the primaries, George H. W. Bush, to be his running mate. His relaxed and confident appearance during the televised Reagan–Carter debate on October 28 boosted his popularity and helped to widen his lead in the polls. On November 4, Reagan won a decisive victory over Carter, carrying 44 states and receiving 489 electoral votes to Carter's 49 in six states plus D.C. He also won the popular vote, receiving 50.7 percent to Carter's 41.0 percent, with independent John B. Anderson garnering 6.6 percent.
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Jackson Galaxy believes that he can help any "problem cat"—provided that its human guardians follow the advice he provides—and that most behavioral problems result either from triggers in the cat's environment, medical issues with the animal, or mishandling of the cat by humans. Jackson teaches that cats are territorial, needing spaces within homes to call their own and that they send signals when they no longer desire petting, a condition he refers to as "overstimulation." Cats do not like being cornered and lash out when overstimulated. Certain cats (whom he calls "tree- dwelling cats") behave better when they have access to above-ground perches, and he often instructs owners of such cats to install an above-the-floor walkway with no dead ends, in order to provide these cats with the psychological comfort of escape routes.
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These levels are maintained via the recycling of glutamate molecules in the neuronal-glial cell process known as the glutamate–glutamine cycle, in which glutamate is synthesized from its precursor glutamine in a controlled manner in order to maintain an adequate supply of the neurotransmitter. However, when glutamate molecules in the synaptic cleft cannot be degraded or reused, often due to dysfunction of the glutamate–glutamine cycle, the neuron becomes significantly overstimulated, leading to a neuronal cell death pathway known as apoptosis. Apoptosis occurs primarily via the increased intracellular concentrations of calcium ions, which flow into the cytosol through the activated glutamate receptors and lead to the activation of phospholipases, endonucleases, proteases, and thus the apoptotic cascade. Additional sources of neuronal cell death related to excitotoxicity involve energy rundown in the mitochondria and increased concentrations of reactive oxygen and nitrogen species within the cell.
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A further demonstration that macrophages could be activated by lymphokines in vivo was important in the laboratory's subsequent clinical efforts to treat diseases in which macrophages achieve both intracellular and extracellular killing." Cohn called macrophages the "versatile element of inflammation," with some of their secretions resulting in the healing of wounds, the repair of tissues, or the destruction of microbes and tumors, while excessive amounts of secretions from overstimulated microphages can intensify various diseases, including rheumatoid arthritis and atherosclerosis. An interview with Cohn described the discovery of the secretory role of macrophages as follows: "A major immunological finding, which has come primarily from work in Dr. Cohn's laboratory, is that macrophages are not just eaters. In addition to the chemicals they make to kill and degrade the cells they ingest, they also secrete many molecules into their surrounding environment, affecting the activity of other cells.
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By 1965, the band was deeply intertwined in the Strip's live scene, appearing regularly at venues such as Pandora's Box, the Hullabaloo, and the Whisky a Go Go, and sharing the bill with highly-influential Los Angeles acts, including the Seeds, the Doors, and Love. Later in the year, Impression Records approached the Sloths to record their debut single at CBS Studios. Described by music critic Jonny Whiteside as a "masterpiece of overstimulated teenage arousal", it featured the two original songs "Makin' Love" and "You Mean Everything to Me". Although the single was not too commercially successful, largely due to a lack of promotional support, another garage band, the Dirty Shames, covered "Makin' Love" a year later on the same record label. In 1966, Briskin left the band to enroll in law school; thus, causing the Sloths to disband by the end of year.
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