A subsequent biopsy revealed a malignant tumor in her uterus.
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It was a malignant tumor in her abdomen, not breast cancer.
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It was a malignant tumor from a type of cancer called sarcoma.
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It said she had started treatment for "a malignant tumor" that was discovered early.
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Winnie Palmer died of a malignant tumor in her abdomen in 1999 at 65.
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The image revealed a mass on her right lung that turned out to be a malignant tumor.
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I've never fallen out of love with anyone and must be extracted carefully like a malignant tumor.
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The court said in a statement that a biopsy performed July 31 confirmed a localized malignant tumor.
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The military section of China's Global Times newspaper on Thursday referred to THAAD as "a malignant tumor".
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The bump swelled into a lump and, later, a malignant tumor, a carcinoma the size of Cleveland.
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In August, the Supreme Court announced that she was treated for a malignant tumor on her pancreas.
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" Palma, though, believed the risk was worth it, "given that it was supposed to be a malignant tumor.
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After posting a 2.01 E.R.A. in 1962, Umbricht was found to have a malignant tumor in his leg.
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Justice Ginsburg, 86, underwent treatment for a malignant tumor that was discovered after a blood test in July.
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Those who are diagnosed with the malignant tumor have a median survival rate of about 14 to 14.5 months.
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Since leaving office, the man widely known as simply Lula underwent chemotherapy to treat a malignant tumor in his larynx.
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In April, Carrie was diagnosed with glioblastoma, an aggressive, rapidly growing malignant tumor that can affect the brain and spinal cord.
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An assessment this spring revealed a recurrence of a malignant tumor that had been operated on in the summer of 2015.
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"Instead of welcoming the cultural diversity of Uighurs, China labeled it a malignant tumor," said Mr. Yalqun, who lives in Philadelphia.
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Even though they were dealing with a malignant tumor, he said, it was considered low intensity, meaning no chemotherapy will be needed.
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When a malignant tumor appeared on Tika's leg, Kobuk wouldn't leave Tika's side, even after she had to have her leg amputated.
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"I was told that it was most likely a malignant tumor which would require radiation and chemo even after the surgery," said Palma.
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In the new study, all 25 patients were hospitalized for abdominal surgeries, about 224 percent of them involving removal of a malignant tumor.
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Armstrong's daughter Karen dies early on in the film, taken from the Armstrongs as a child due to a malignant tumor and pneumonia.
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To treat the malignant tumor, Ginsburg underwent three weeks of radiation therapy, completed on Friday at Memorial Sloan Kettering Cancer Center in New York.
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Kim Vaillancourt was diagnosed with glioblastoma – an aggressive, rapidly-growing malignant tumor affecting the brain or spine – in December, she told the Associated Press.
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Since then, he underwent chemotherapy to treat a malignant tumor in his larynx before revealing, in February 2012, that his cancer was in remission.
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According to the American Brain Tumor Association, glioblastoma is an especially malignant tumor that forms in the tissue of the brain and spinal cord.
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Of a patient's malignant tumor, the Greek physician wrote: it had "veins stretched on all sides, as the animal the crab has its feet".
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The unnamed Company, like a malignant tumor, has spread across and corrupted not only the surrounding City but branching timelines, alternate versions of the world.
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Despite suffering from ductal carcinoma, a malignant tumor that affects his prostate, Dr. NakaMats looked in good health, if a little sullen, when I met him.
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Ginsburg disclosed her most recent brush with cancer last summer, completing a three-week course of radiation therapy to treat a malignant tumor on her pancreas.
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As Simone Giertz continues to recover from brain surgery she underwent to remove a non-malignant tumor, she's updating fans on her progress as honestly as possible.
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I said that I'd become interested in Dan's accounts of cancer—the claim that he'd had a malignant tumor, and that his mother had died of cancer.
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The abnormality was first detected after a routine blood test in early July, and a biopsy performed on July 31 at Sloan Kettering confirmed a localized malignant tumor.
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After he was taken in for an examination, doctors found a malignant tumor growing on his spine, a form of bone cancer called osteosarcoma which required urgent surgery.
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Now, a study reveals a malignant tumor in the foot of a 1.7 million-year-old hominin, an extinct human species—the oldest known case of human cancer.
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" The Supreme Court announced in August that Ginsburg had undergone the three weeks of radiation treatment for a malignant tumor on her pancreas, saying she "tolerated treatment well.
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Ginsburg completed a three-week course of radiation therapy in August to treat a malignant tumor on her pancreas that was detected in early July after a blood test.
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He finished his second term in January 2011 with a 90% approval rating, just months before it was announced he would undergo chemotherapy for a malignant tumor in his larynx.
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Lula finished his second term in January 2011 with a 90% approval rating, just months before it was announced he would undergo chemotherapy for a malignant tumor in his larynx.
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Her doctors discovered the tumor in July after a routine blood test, and a biopsy at Memorial Sloan Kettering Cancer Center in New York City confirmed a localized malignant tumor.
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An M.R.I. of his brain seemed redundant but confirmed the diagnosis: A four-centimeter malignant tumor was invading his right frontal cortex, the seat of his personality, where "Dad" lived.
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In February 2014, Mr. Hamm was found to have a large malignant tumor behind his left eye, filling the socket where the nerves from his brain went into his eye.
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Despite undergoing three weeks of radiation treatment for a malignant tumor on her pancreas in August, Ginsburg was on the bench earlier this month as the court began the latest term.
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Dr. Delaney's team identified it as a malignant tumor and diagnosed adenocarcinoma, a type of cancer that develops from the body's mucus-secreting glands, like the salivary glands or mammary glands.
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While we're on the topic of double standards, the conflicts of interest juxtaposition of the Clinton and Trump foundations alone is like comparing apples to a malignant tumor shaped like an orange.
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Justice Ginsburg, 86, one of four liberal justices on the nine-member court, told CNN in a wide-ranging interview on Tuesday that treatment for a malignant tumor on her pancreas had been successful.
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The players and coaches formed an "instant bond" with the personable and upbeat Stone — and their support helped him stay positive when doctors told him his malignant tumor had only a 50 percent survival rate.
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I tapped out around the two-hour mark when the goblin king of the uncanny valley entered the film, swinging his malignant tumor of a chin into my personal space, courtesy of 3D movie magic.
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This is the first time she's spoken out this candidly since she criticized President Trump and described him as a "malignant tumor eating its way through our constitution" back in April in a since-deleted tweet.
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Scientists have identified a malignant tumor in a foot bone of a 1.6-1.8 million-year-old hominin fossil from South Africa, and a benign tumor in a 2 million-year-old hominin at a nearby site.
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Carrie DeKlyen, 37, was diagnosed with glioblastoma in April — an aggressive, rapidly growing malignant tumor that can affect the brain and spinal cord — but opted to avoid experimental treatment to save her baby, whom her family named Life Lynn DeKlyen.
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" According to Cincinnati Children's Hospital, the type of tumor McKenna had is "a rare, malignant tumor of cells that line the yolk sac of the embryo" and is "most often found in children before the ages of 1 to 2.
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Ginsburg, the oldest member of the high court and a favorite on the left, has faced multiple bouts of cancer during her time on the bench, most recently undergoing radiation treatment for a malignant tumor on her pancreas last month.
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"CJ was diagnosed with Hodgkin's lymphoma initially, if that isn't bad enough they were just given the news that he has a malignant tumor in his abdomen, [and] gastroperisis," reads the page's description, written as if it were posted by a family friend.
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The LaFrances, both 35, allegedly began publicizing the ruse in the spring of 2017 and started a GoFundMe account claiming CJ had been diagnosed with Hodgkin lymphoma, a malignant tumor in his abdomen and gastroparesis, a condition that affects the stomach muscles.
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He used a cocktail called Coley's toxins to create infections in his cancer patients in an effort to trigger their immune systems to attack not only those bacterial infections but other parts of the body that appeared foreign, such as a malignant tumor.
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Even incidental exposure to asbestos, a fireproof fiber material once used to insulate buildings before we became aware of its risks, can cause cancers of the lung and mesothelioma, a malignant tumor of the tissue that lines the lungs, stomach, heart, and other organs.
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Now, the Michigan mother of five who was diagnosed with glioblastoma — an aggressive, rapidly growing malignant tumor that can affect the brain and spinal cord — lies in a "vegetative state" in a Michigan hospital, inching toward death so her unborn child can have a chance at life.
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The Alice onstage is given, in addition to Calvin's words, some of her own, drawn from two of her published works about illness: "Dear Bruno," a letter to a 12-year-old boy hospitalized with a malignant tumor, and "Of Dragons and Garden Peas," an influential essay about the patient's experience of cancer treatment.
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On Friday, less than 24 hours later, the court announced that Ginsburg had secretly finished a three-week course of radiation therapy at Memorial Sloan Kettering Center in New York City for a localized malignant tumor on her pancreas — the second time within a year Ginsburg has had cancer and the second time she has had pancreatic cancer.
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With that said... Seeing a doctor is the only way to diagnose breast cysts Unless you have X-ray vision (and if you do, please drop us a line to let us know how that's working out for you!), you can't differentiate between a benign cyst and a malignant tumor just by feeling it under your skin.
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Justice Ruth Bader GinsburgRuth Bader GinsburgGinsburg makes first public appearance since cancer news David Axelrod after Ginsburg cancer treatment: Supreme Court vacancy could 'tear this country apart' Ginsburg again leaves Supreme Court with an uncertain future MORE on Friday completed three weeks of radiation treatment for a malignant tumor on her pancreas, the Supreme Court announced.
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Supreme Court Justice Ruth Bader GinsburgRuth Bader GinsburgGinsburg says O'Connor once shared advice on working while getting cancer treatment Ginsburg after cancer treatment: 'I am pleased to say that I am feeling very good tonight' McConnell: GOP would 'absolutely' fill Supreme Court seat next year MORE said Tuesday night she is feeling "very good" after completing three weeks of radiation treatment for a malignant tumor on her pancreas.
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In 1976, Stanphill was diagnosed with "a malignant tumor in the right front quadrant of the brain." He underwent successful surgery, living for 17 more years.
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On 2015, after he got injured on his left knee ligament, doctors found a malignant tumor os his left leg. Later on, he won the battle against cancer.
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Adenosquamous lung carcinoma (AdSqLC) is a biphasic malignant tumor arising from lung tissue that is composed of at least 10% by volume each of squamous cell carcinoma (SqCC) and adenocarcinoma (AdC) cells.
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Now retired, is engaged in volunteer work, after having fought since 2006 to eradicate a malignant tumor. Along with Corinna Andreatta, is among the founders of Chiliamacisegua, partnership non-profit for the protection of animals.
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A malignant tumor was found in Bliss's throat in early 1959. He died in his sleep on January 22, 1960, at the age of 94. His wife, May Bortz Bliss, died seven years later in 1967.
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Karcioglu Z, Semeren A, Mathes SJ (1977) Ectomesenchymoma. A malignant tumor of migratory neural crest (ectomesenchyme) remnants showing ganglionic, schwannian, melanocytic and rhabdomyoblastic differentiation. Cancer 39:2486-2496. 6\. Cozzutto C, Comelli A, Bandelloni R (1982) Ectomesenchymoma.
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Reports from C.I.M. state that he died from a malignant tumor (cancer). William had suffered head injuries since he first arrived in China. Malignant had a different meaning than we know it today. It meant chronic or continuous.
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Tumor antigens are antigens produced by tumor cells and can be common among patients with the same cancer-type, or unique to a particular patient. Their specificity to malignant tumor cells makes tumor antigens ideal candidates for vaccination.
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Renal oncocytoma is considered benign, cured by nephrectomy. There are some familial cases in which these tumors are multicentric rather than solitary.Robbins pathology, page 1015 However, they may be resected to exclude a malignant tumor, e.g. renal cell carcinoma.
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CADs can be used to identify subjects with Alzheimer's and mild cognitive impairment from normal elder controls. In 2014, Padma et al. used combined wavelet statistical texture features to segment and classify AD benign and malignant tumor slices. Zhang et al.
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Pinealoblastoma is a malignant tumor of the pineal gland. A pinealoblastoma is a supratentorial midline primitive neuroectodermal tumor. Pinealoblastoma may occur in patients with hereditary uni- or bilateral retinoblastoma. When retinoblastoma patients present with pinealoblastoma this is characterized as "trilateral retinoblastoma".
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29, 1575-1591. doi:10.1128/MCB.01300-08 Endotrophin, a peptide generated by ColVI in white adipose tissue, has been shown to promote the growth of breast cancer cells.Park, J. and Scherer, P. E. (2012). Adipocyte- derived endotrophin promotes malignant tumor progression.
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On October 27, 1966, shortly after he had undergone a routine physical, Erdelatz had surgery to remove a malignant tumor from his stomach. His cancer spread and caused his death two weeks later. His funeral was attended by more than three hundred people.
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The malignant tumor that cost Bader his eye eventually resurfaced. Bader/Johnson died on September 16, 1966, at St. Joseph's Medical Hospital in Omaha. His death meant that the question of whether he was an amnesiac or a hoaxer was never resolved.
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Neuroendocrine carcinoma of the cervix is best defined separately:Neuroendocrine: Of, relating to, or involving the interaction between the nervous system and the hormones of the endocrine glands.Carcinoma: An invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body.
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After suffering shortness of breath at a Teamsters executive board meeting, Fitzsimmons underwent surgery in late December 1979 which removed a non-malignant tumor in his bronchial passage."Fitzsimmons, Teamsters Chief, Is Back on the Job After Surgery." New York Times. January 7, 1980.
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Pradel was admitted to Edward Hospital in Naperville in the summer of 2018 for back pain. While there, doctors found a malignant tumor that spread across his body. He entered hospice care on September 2, 2018, and died one day shy of his 81st birthday.
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In 2010, while writing the book Half Empty, Rakoff was diagnosed with a malignant tumor and Hodgkin's lymphoma, and later developed a post-radiation sarcoma behind his left collarbone and began chemotherapy.Interview on the Daily Show, October 14, 2010 He died in Manhattan on August 9, 2012.
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Differentiation therapy is an approach to treating advanced cancers in which malignant cells are encouraged to differentiate into more mature forms using pharmacological agents. The basis of the therapy stems from the tendency of malignant tumor cells to assume a less specialized, stem cell-like dedifferentiated state.
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The presence of chromosomal aberrations has been demonstrated in every type of malignant tumor. Since the role of the BFB cycle in inducing chromosomal instability in tumors has been well established, it is believed to play a significant part in the genesis of various tumor types.
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Secondary malignant neoplasm is a malignant tumor whose cause is the treatment (usually radiation or chemotherapy) which was used for a prior tumor. It must be distinguished from Metastasis from the prior tumor or a relapse from it since a secondary malignant neoplasm is a different tumor.
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Biphenotypic sinonasal sarcoma is a newly recognized, very rare, low grade malignant tumor of the nasal cavity which was formerly probably included in fibrosarcoma and synovial sarcoma cases. It was incorporated into the fourth edition of the World Health Organization Classification of Head and Neck Tumours, published in 2017.
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Specific active immunotherapy administers a specific antigen as the therapy. The therapy allows the host to create an antigen-specific response with the development of antibodies, proliferation of cytotoxic T lymphocyte responses, or both, directed at the desired pathogen or malignant tumor cell in the case of cancer therapy.
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In December 2007, Copeland began treatment for a malignant tumor of the salivary glands, caused by Merkel cell carcinoma, a rare form of cancer. Copeland had sought experimental treatments in Germany but died in Munich on Easter Sunday, March 23, 2008, aged 64. He was buried in Metairie Cemetery.
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Anderson was diagnosed with testicular cancer at the age of 36. He was diagnosed after recognizing his symptoms while reading a medical magazine. Because of a malignant tumor, he had to have his left testicle removed. Anderson died on May 5, 2002 as a result of the testicular cancer.
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The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.
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In 1993, he was also battling against "Hodgkin's disease" which is, a malignant tumor of the lymphatic system. He had several chemotherapy treatments. Five years later, he had defeated the cancer, he states "I've been cancer-free for 25 years" in 2015. He owns a boot from Frida of ABBA.
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Büşra Ün was born in Izmir. At the age of six-and- half-months, her parents noticed that she has no feeling at her feet. She was diagnosed with neuroblastoma having a malignant tumor in her right abdomen. After one-and-half-year-long chemotherapy and two surgeries, the tumor was removed.
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In 1876 he began law studies in Kristiania. In 1882 he developed a malignant tumor in the palate. He was operated on, both in Norway and in Germany, but died the following year. His musical compositions were modest in number consisting of 15 songs and 9 piano pieces besides an orchestra overture.
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Foster was sentenced to 60 years in prison for Rich's murder, and Prince was sentenced to 50 years. The murder prompted Rush to prioritize efforts to reduce gun violence. In 2008, Rush had a rare type of malignant tumor removed from his salivary gland. Rush is a member of Iota Phi Theta.
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Michael Richard (1948 – August 28, 2006) was an American professional rock musician and amateur photographer. In 2002, surgery to remove a malignant tumor behind his right eye left him legally blind, and he began taking abstract photos of urban scenes. Those images have been exhibited at galleries in San Francisco and Los Angeles.
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LIM-kinase, a member of one of the protein families, plays a role in the development of collective migration by tumor cells. This protein is known to be involved in the regulation of developing invadopodias, which are structures typical of malignant tumor cells and responsible for the destruction of the surrounding extracellular matrix.
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In extremely rare cases, a malignant tumor may develop within the parathyroid gland. They can be detected intraoperatively, imaging, or through blood testing. A thick fibrous capsule is usually present around the gland, as opposed to the thin capsule present in benign adenomas. Parathyroid hormone level is often greater in carcinomas than in benign disorders.
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Vaginal cancer is a malignant tumor that forms in the tissues of the vagina. Primary tumors are most usually squamous cell carcinomas. Primary tumors are rare, and more usually vaginal cancer occurs as a secondary tumor. Vaginal cancer occurs more often in women over age 50, but can occur at any age, even in infancy.
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A thymoma is a tumor originating from the epithelial cells of the thymus that may be benign or malignant. Thymomas are frequently associated with the neuromuscular disorder myasthenia gravis; thymoma is found in 20% of patients with myasthenia gravis. Once diagnosed, thymomas may be removed surgically. In the rare case of a malignant tumor, chemotherapy may be used.
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Esthesioneuroblastoma is a slow developing but malignant tumor with high recurrence rates because of its anatomical position. The tumor composition, location and metastatic characteristics as well as the treatment plan determine prognosis. Common clinical classification systems for esthesioneuroblastoma include the Kadish classification and the Dulguerov classification. Histopathological characteristics on top of Kadish classification can further determine cancer prognosis.
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These ovarian tumors are usually multi-septated, cystic masses with thin walls. They also contain varying amounts of solid tissue which consists of proliferating stromal tissue, papillae, or malignant tumor cells. Benign mucinous cystadenomas compose 80% of mucinous ovarian tumors and 20–25% of benign ovarian tumors overall. The peak incidence occurs between 30 and 50 years of age.
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After one semester, they moved into a house in Antelope Valley, near Edwards AFB. Janet did not finish her degree, a fact she regretted later in life. The couple had three children: Eric, Karen, and Mark. In June 1961, Karen was diagnosed with a diffuse intrinsic pontine glioma, a malignant tumor of the middle part of her brain stem.
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The most common bacterial isolates from anal gland infection are E. coli, Enterococcus faecalis, Clostridium perfringens, and Proteus species. Increasing dietary fiber is also commonly recommended. Anal sacs may be removed surgically in a procedure known as anal sacculectomy. This is usually done in the case of recurrent infection or because of the presence of an anal sac adenocarcinoma, a malignant tumor.
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In August 2010, after a medical screening he has been diagnosed with a malignant tumor on right scapula that had threatened to end his playing career. After a surgical intervention in Bologna, and a period of recovery, during which he had the undivided support of the public in Serbia, in January 2011 doctors confirmed that he could play professional football again.
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Kyle's mother takes Rose's job at the doll factory and Kyle's humdrum life working two jobs continues as it did before. The DVD release of the film also contains a deleted scene in which Martha has a CAT scan revealing that she has a severely malignant tumor in her brain. The doctor explains that the tumor could cause blackouts and highly abnormal behavior.
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The BCG vaccine has been used against tuberculosis, mycobacteria, and various cancers in the form of vaccination as an initial immune system stimulant. In cancer, the anti-tumor immunological effects are elicited by the host's immune response and the BCG infection against the tumor cells, most commonly in bladder cancer. The immune activation allows for further recognition and elimination of malignant tumor cells.
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Combined small cell lung carcinoma (or c-SCLC, and rarely rendered as "small- cell lung carcinoma") is a form of multiphasic lung cancer that is diagnosed by a pathologist when a malignant tumor arising from transformed cells originating in lung tissue contains a component of small cell lung carcinoma (SCLC) admixed with one (or more) components of non-small cell lung carcinoma (NSCLC).
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Michael J. Reardon is an American cardiac surgeon and medical researcher. He is known for his work in heart autotransplantation for malignant heart tumors, an operation in which the surgeon removes the patient's heart, cuts out the malignant tumor, and reimplants the heart back in the patient's chest. He performed the first successful heart autotransplantation for a cancerous heart tumor in 1998.
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The Shibutanis are not competing in the 2019-2020 season. This is the second season the Shibutanis have not competed in since the 2017–2018 season. On December 16, 2019, Maia revealed that she had a successful surgery to remove a malignant tumor on her kidney. It was unsure at the time how the tumor would affect her ability to compete.
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An ultrasound revealed a malignant tumor in his bladder, which was removed. This resulted in several postponed shows, and Gahan underwent cancer treatments during the remaining three months of the tour. Gahan later suffered a torn calf muscle while performing in Bilbao, Spain, on 9 July 2009, resulting in two further cancellations."Dave Gahan injured – Depeche Mode Cancel Final 2 Shows in Europe" Side-Line.com.
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Malignant tumor cells perform glycolysis at a rate that is ten times faster than their noncancerous tissue counterparts. During their genesis, limited capillary support often results in hypoxia (decreased O2 supply) within the tumor cells. Thus, these cells rely on anaerobic metabolic processes such as glycolysis for ATP (adenosine triphosphate). Some tumor cells overexpress specific glycolytic enzymes which result in higher rates of glycolysis.
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John Neir, the founder of Medicare Resources Ltd, suffered from a malignant tumor in 1993. After exhausting chemotherapy, Neir left Evangel Hospital of Hong Kong in which he was the former Premier. Neir and his wife, being US missionaries of Evangelical Free Church, have strong collaboration with other missionaries. Mrs Neir got in touch with a missionary whose wife is a Chinese coming from Wuhan.
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On May 13, 2013, Schmidt had brain surgery to excise a malignant tumor. At first, nobody knew about it except for his family. The press found out about the disease fifteen days after the surgery at a dinner celebrating the 50th anniversary of the two-time World Champion senior men's Brazilian National Team. Schmidt did not appear as he was recuperating from daily chemotherapy sessions.
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Gumbel raised two children with his wife, June, in semi-rural Waccabuc, north of New York City. In 2001, he divorced her to marry Hilary Quinlan. Around 2002, he shed 55 pounds of weight in seven months after he stepped on the scale to find out he was 240 pounds. In October 2009, he had surgery to remove a malignant tumor near one of his lungs.
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The hallmark of a malignant tumor is its tendency to invade and infiltrate local and adjacent structures and, eventually, spread from the site of its origin to non-adjacent regional and distant sites in the body, a process called metastasis. If unchecked, tumor growth and metastasis eventually creates a tumor burden so great that the host succumbs. Carcinoma metastasizes through both the lymph nodes and the blood.
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In September 1964, Cole began to lose weight and he experienced back problems. He collapsed with pain after performing at the Sands Hotel in Las Vegas. In December, he was working in San Francisco when he was finally persuaded by friends to seek medical help. A malignant tumor in an advanced state of growth on his left lung was observed on a chest X-ray.
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After doctors found a malignant tumor under his sternum, Linville underwent surgery in February 1998 to remove part of his lung. He received further treatment, but had continuing health problems over the next two years. Linville died of pneumonia in New York City on April 10, 2000, after complications from cancer surgery. His ashes were scattered at sea off the coast of Bodega Bay, California.
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The intellectual engagement between Kant and Garve extended up to Garve's death of cancer"In his letter to Kant, September 1798 [819], Garve movingly depicts his agonizing illness, a malignant tumor of the face, and expresses his astonishment that he is still living and thinking." (Kant: Philosophical Correspondence 1759-99, Edited and translated by Arnulf Zweig, University of Chicago Press, 1967, p. 250, note 2) in 1798.
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Cytology of an anal sac adenocarcinoma An anal sac adenocarcinoma is an uncommon and aggressive malignant tumor found in dogs that arises from the apocrine glandular tissue of anal sac. The disease exists in cats as well, but is much less common in that species. They are the second most common cancerous cause of hypercalcaemia (high serum calcium) in dogs, following T-cell lymphoma.
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This condition is associated with a high risk of developing osteosarcoma (malignant tumor of the bone). RECQL4 gets its name from being homologous (sharing sequence) with other members of the RecQ helicase family. Two other genetic diseases are due to mutations in other RECQ helicases. Bloom syndrome is associated with mutations in the BLM gene and Werner syndrome is associated with mutations in the WRN gene.
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A Vaccine- associated sarcoma (VAS) is a type of malignant tumor found in cats (and rarely, dogs and ferrets) that has been linked to certain vaccines. Concern about VAS has resulted in changes in recommended vaccine protocols to limit the type, frequency, and sites of vaccinations. Owners are advised to monitor injection sites for signs of tumors and contact their veterinarian immediately if one develops.
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In 1971, Halprin was diagnosed with a malignant tumor in her colon; this sudden shift in her life inspired her to investigate and create associations to make a personal ritual that helped her healing process. She used the investigative and therapeutic tools she had learned from Fritz Perls in order to understand and duplicate the psychological behaviors put into performances.Ross, Janice. Anna Halprin: Experience as Dance.
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He received a teaching degree and then studied law at the University of Buenos Aires. He left in the third year and joined a political union. La Porta married Silvia Ines Foster and had three children: Mary Florence, Natalia and Nicholas. He died on April 1 of 2007 at the Italian Hospital, where he remained hospitalized for two weeks because of a malignant tumor.
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Adenosarcoma (also Mullerian Adenosarcoma) is a rare malignant tumor that occurs in women of all age groups, but most commonly post-menopause. Adenosarcoma arises from mesenchymal tissue and has a mixture of the tumoral components of an adenoma, a tumor of epithelial origin, and a sarcoma, a tumor originating from connective tissue.NCI Dictionary of Cancer Terms: Adenosarcoma.” National Cancer Institute, National Institutes of Health, www.cancer.gov/publications/dictionaries/cancer-terms/def/adenosarcoma.
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In 2015, Faria was diagnosed with an aggressive stomach cancer. In August 2015, a doctor of conventional medicine, Raul Cutait, extracted a malignant tumor of 6 cm - a gastric adenocarcinoma. The surgery and follow-up of 5 months of chemotherapy took place at the Hospital Sírio-Libanês in São Paulo. Faria did not report these facts to the public, originally saying he was being hospitalised for a stomach hernia.
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S100 is integral in the fight against cancer, S100 induces phagocytes that phagocytize malignant tumor cells which results in apoptosis. Proteoglycans are another class of molecules that display this duality, under certain chemical conditions these molecules can emerge as inhibitors or promoters. Recent studies have shown that proteoglycans can play an integral role in the metastasis of cancer. Another molecule that falls within this class of molecules is DKK1.
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1 (1987), pp. 2–9. In 1982, he moved into the newly built Indiana University Retirement Community, an assisted living facility. A heavy smoker, he suffered a heart attack in June 1984 and was diagnosed with a malignant tumor at the beginning of October; he died nine weeks later. In accordance with his wishes, his mortal remains were interred alongside those of Dieter Cunz at the Walnut Grove Cemetery in Worthington.
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He was born in Zaragoza, in Aragon, Spain on 7 January 1916 and died at Hospital Militar Gómez Ulla in Madrid on 31 July 1990 from a liver failure during or following surgery to remove a malignant tumor in the pancreas. He was interred in Madrid. Fernando Sancho fought in the spanish Civil War on the rebel side, being wounded several times and achieving the rank of lieutenant in the Legion.
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In 1976 Johnson was diagnosed with cancer and had a malignant tumor removed from his lung.Associated Press, "LBJ's Brother Has Surgery", Aiken Standard, 9 December 1976 His lung cancer returned, and Johnson died at Holy Cross Hospital in Austin, Texas on December 11, 1978.Associated Press, "Sam Johnson is Dead at Age 64", Spartanburg Herald- Journal, 12 December 1978 He is buried in the Johnson Family Cemetery in Stonewall, Texas.
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Tennis announced in his column of November 19, 2009, that he has been diagnosed with a chordoma, a rare malignant tumor that usually occurs in the spine and base of the skull. On Monday, September 30, 2013 Tennis posted on his Facebook page that he had been fired by Salon. He also noted this in the comments section to his column on that date. No explanation for the firing was provided.
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In 1982, Yellowman was diagnosed with skin cancer, and was told that he only had three more years to live. However, this prognosis proved to be inaccurate, and after several surgeries Yellowman was able to continue his career. The cancer went into apparent remission during this time. In 1986 it was diagnosed that the cancer had spread to his jaw; Yellowman underwent very invasive jaw surgery to remove a malignant tumor.
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A carcinoid (also carcinoid tumor) is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases, metastasis may occur. Carcinoid tumors of the midgut (jejunum, ileum, appendix, and cecum) are associated with carcinoid syndrome. Carcinoid tumors are the most common malignant tumor of the appendix, but they are most commonly associated with the small intestine, and they can also be found in the rectum and stomach.
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After inflammation, restoration of normal tissue integrity and function is preserved by feedback interactions between diverse cell types mediated by adhesion molecules and secreted cytokines. Disruption of normal feedback mechanisms in cancer threatens tissue integrity and enables a malignant tumor to escape the immune system. An example of the importance of the wound healing response within tumors is illustrated in work by Howard Chang and colleagues at Stanford University studying Breast cancers.
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On March 7, Mancini left the Orioles during spring training to undergo a non- baseball medical procedure. On March 12, it was revealed that the procedure was the removal of a malignant tumor from his colon. On April 28, Mancini revealed he had stage 3 colon cancer and will begin chemotherapy ongoing for six months to treat his cancer. Mancini said if baseball resumed in 2020, it would probably be without him.
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Several sons went on to become successful stallions while his daughters also became successful producers, causing Deputy Minister to be the leading broodmare sire of 2007. His stud fee reached $150,000 for the years 1999 to 2002. In 1988, he was inducted into the Canadian Horse Racing Hall of Fame. Deputy Minister died of a malignant tumor at the Ohio State University veterinary hospital in Columbus, Ohio, and was buried at Brookdale Farm.
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He left in 1981 to join International Gold and Minerals Limited as vice president for financial and corporate affairs. In February 1982, Swigert left International Gold and Minerals Limited to run for U.S. Congress in the newly-created 6th district as a Republican. Swigert developed a malignant tumor in his right nasal passage, which he disclosed to voters. Doctors told him he would finish radiation treatments June 15 and make a complete recovery.
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Along with single cell migration, collective cell migration can occur when groups of firmly interconnected tumor cells are migrating. This type of migration indicates tissue rearrangement, underlies the processes of embryonic morphogenesis, and also is an essential component in the healing of wound surfaces. Therefore, the key is that malignant tumor cells extensively use the mechanisms of both collective and single cell migration as physiological prototypes in the process of invasive growth and metastasis.
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August 31, 2015 Shortly after returning from Virginia, doctors diagnosed a malignant tumor on the right side of her brain. She underwent brain surgery at Graduate Hospital in Philadelphia on January 13, 1968. After recovering from her first surgery, Terrell returned to Hitsville studios in Detroit and recorded "You're All I Need to Get By". Both that song and "Ain't Nothing Like the Real Thing", reached No. 1 on the R&B; charts.
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In February 2014, Hamm, who was still on death row, was diagnosed with lymphatic and cranial cancer. Doctors discovered a large malignant tumor behind his left eye and determined that Hamm suffered from B-cell lymphoma. Doctors also discovered “numerous abnormal lymph nodes” in Hamm's abdomen, lungs, and chest. Hamm underwent years of cancer treatment, including radiation therapy, but the treatments did not eliminate the cancer entirely and, by late 2017, Hamm's cancer had worsened.
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In his research of renal tumors, he proposed that tumor cells originate during the development of the embryo. He published his findings in an influential 1899 monograph titled Die Mischgeschwülste der Niere. As a result of his extensive work involving renal tumors, another name for "nephroblastoma" is Wilms' tumor, a malignant tumor of the kidney. Wilms made several contributions as a surgeon, and is credited for introducing a partial rib resection used in the treatment for pulmonary tuberculosis.
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Theodora's death is recorded by Victor of Tonnena, with the cause uncertain but the Greek terms used are often translated as "cancer." The date was 28 June 548 at the age of 48. Later accounts frequently attribute the death to breast cancer, although it was not identified as such in the original report where the use of the term "cancer" probably referred to "a suppurating ulcer or malignant tumor". Other sources report that she died at 51.
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Oral squamous cell carcinoma is the end product of an unregulated proliferation of mucous basal cells. A single precursor cell is transformed into a clone consisting of many daughter cells with an accumulation of altered genes called oncogenes. What characterizes a malignant tumor over a benign one is its ability to metastasize. This ability is independent of the size or grade of the tumor (often seemingly slow growing cancers like the adenoid cystic carcinoma can metastasis widely).
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Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be primary (starts within the eye) or metastatic cancer (spread to the eye from another organ). The two most common cancers that spread to the eye from another organ are breast cancer and lung cancer. Other less common sites of origin include the prostate, kidney, thyroid, skin, colon and blood or bone marrow.
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In Latin, cancer translates to "malignant tumor" or literally "crab" (related to the likening of sectioned tumors to the limbs of a crab). The closely related word in Middle English and Old North French, chancre, now more usually applied to syphilis, is also thought to be involved. Despite this etymology, aphthous stomatitis is not a form of cancer but rather entirely benign. An aphtha (plural aphthae) is a non specific term that refers to an ulcer of the mouth.
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High amount of aerobic glycolysis (also known as the Warburg effect) distinguishes cancer cells from normal cells. The conversion of glucose to lactate rather than metabolizing it in the mitochondria through oxidative phosphorylation, (which can also occur in hypoxic normal cells) persists in malignant tumor despite the presence of oxygen. This process normally inhibits glycolysis which is also known as Pasteur effect. One of the reasons it is observed is because of the malfunction of mitochondria.
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Gliomatosis cerebri is a rare primary brain tumor. It is commonly characterized by diffuse infiltration of the brain with neoplastic glial cells that affect various areas of the cerebral lobes. These malignancies consist of infiltrative threads that spread quickly and deeply into the surrounding brain tissue, or into multiple parts of the brain simultaneously, making them very difficult to remove with surgery or treat with radiation. Gliomatosis cerebi behaves like a malignant tumor that is very similar to Glioblastoma.
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Some anticancer drugs target mtDNA and have shown positive results in killing tumor cells. Research has used mitochondrial mutations as biomarkers for cancer cell therapy. It is easier to target mutation within mitochondrial DNA versus nuclear DNA because the mitochondrial genome is much smaller and easier to screen for specific mutations. MtDNA content alterations found in blood samples might be able to serve as a screening marker for predicting future cancer susceptibility as well as tracking malignant tumor progression.
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A vaccine-associated sarcoma (VAS) or feline injection-site sarcoma (FISS) is a type of malignant tumor found in cats (and often, dogs and ferrets) which has been linked to certain vaccines. VAS has become a concern for veterinarians and cat owners alike and has resulted in changes in recommended vaccine protocols. These sarcomas have been most commonly associated with rabies and feline leukemia virus vaccines, but other vaccines and injected medications have also been implicated.
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It is a rare malignant tumor that primarily develops in children, and accounts for approximately 1% of all cancers in children and 79% of all primary liver cancers under the age of 15. Most hepatoblastomas form in the right lobe. Liver cancer can also come from other structures within the liver such as the bile duct, blood vessels and immune cells. Cancer of the bile duct (cholangiocarcinoma and cholangiocellular cystadenocarcinoma) account for approximately 6% of primary liver cancers.
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A liver metastasis is a malignant tumor in the liver that has spread from another organ affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary tumors. In 50% of all cases the primary tumor is of the gastrointestinal tract, other common sites include the breast, ovaries, bronchus and kidney.
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The zoo once had seven elephants with a mix of African and Asian. Limba was the lone Asian elephant at the zoo, arrived in 1989 and was euthanized in late 2013 at the age of 50 after a malignant tumor was found in her abdomen. The pachyderm was well known for appearing in Bowmanville's annual Santa Claus Parade and several movies. With her death and closure of Toronto Zoo's elephant exhibit, the only zoo in Ontario with elephants is the African Lion Safari.
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Malignant transformation of cells in a benign tumor may be detected by pathologic examination of tissues. Often the clinical signs and symptoms are suggestive of a malignant tumor. The physician, during the medical history examination, can find that there have been changes in size or patient sensation and, upon direct examination, that there has been a change in the lesion itself. Risk assessments can be done and are known for certain types of benign tumor which are known to undergo malignant transformation.
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Crypt of Milton Berle, at Hillside Memorial Park Berle guest-starred as Uncle Leo in the Kenan & Kel special "Two Heads Are Better than None", which premiered in 2000. This would be his last acting role. In April 2001 Berle announced that a malignant tumor had been found in his colon, but he had declined surgery. Berle's wife said the tumor was growing so slowly that it would take 10 to 12 years to affect him in any significant or life-threatening way.
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Although no proof establishes that PIN is a cancer precursor, it is closely associated with cancer. Over time, these cells multiply and spread to the surrounding prostate tissue (the stroma) forming a tumor. Eventually, the tumor may grow large enough to invade nearby organs such as the seminal vesicles or the rectum, or tumor cells may develop the ability to travel in the bloodstream and lymphatic system. Prostate cancer is considered a malignant tumor because it can invade other areas of the body.
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Kisspeptin plays a role in tumor suppression. In a study where malignant tumor cells were injected into a model system, the system was then tested for genes involved in the injected chromosome 6. KISS1 was discovered to be the only gene expressed in non- metastatic cells and absent in metastatic, metastatic meaning the ability for cancer to spread to unconnected areas. This suggested that there Kisspeptin is an essential regulation factor in whether or not a cell will be metastatic or not.
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Two months later, on the day his Iowa State team lost at Drake, John was told he had an inoperable malignant tumor at the base of his esophagus. "It was a bolt out of the blue for someone who lived his life free of smoking or drinking," His son John said later. "There was high stress. But he was always healthy." John was optimistic about returning to Iowa State in 1974-75, but his health worsened and he resigned on July 30, 1974.
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Largely unknown by her husband, she had a vast spiritual correspondence for many years. She was concerned about the "poor" or the "least," but her deteriorating health restricted her ability to respond to this concern. In 1907 her health deteriorated to the extent that she was forced to lead a primarily sedentary life, receiving visitors and directing her household from a chaise longue. In 1911 she had surgery and radiation for a malignant tumor, recovered, and then was bedridden by July 1913.
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Targeted molecular therapy for neuroblastoma involves treatment aimed at molecular targets that have a unique expression in this form of cancer. Neuroblastoma, the second most common pediatric malignant tumor, often involves treatment through intensive chemotherapy. A number of molecular targets have been identified for the treatment of high-risk forms of this disease. Aiming treatment in this way provides a more selective way to treat the disease, decreasing the risk for toxicities that are associated with the typical treatment regimen.
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Transplantation of pluripotent/embryonic stem cells into the body of adult mammals, usually leads to the formation of teratomas, which can then turn into a malignant tumor teratocarcinoma. However, putting teratocarcinoma cells into the embryo at the blastocyst stage, caused them to become incorporated in the cell mass and often produced a normal healthy chimeric (i.e. composed of cells from different organisms) animal iPSc were first obtained in the form of transplantable teratocarcinoma induced by grafts taken from mouse embryos. Teratocarcinoma formed from somatic cells.
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Cooper's grave in Sacred Hearts Cemetery in Southampton, New York On April 14, 1960, Cooper underwent surgery at Massachusetts General Hospital in Boston for an aggressive form of prostate cancer that had metastasized to his colon.Meyers 1998, p. 304. He fell ill again on May 31 and underwent further surgery at Lebanon Hospital in Los Angeles in early June to remove a malignant tumor from his large intestine. After recuperating over the summer, Cooper took his family on vacation to the south of FranceJanis 1999, p. 163.
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Without angiogenesis a tumor cannot grow beyond a limited size Cancer cells are cells that have lost their ability to divide in a controlled fashion. A malignant tumor consists of a population of rapidly dividing and growing cancer cells that progressively accrues mutations. However, tumors need a dedicated blood supply to provide the oxygen and other essential nutrients they require in order to grow beyond a certain size (generally 1–2 mm3). Tumors induce blood vessel growth (angiogenesis) by secreting various growth factors (e.g.
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Normal tissue integrity is preserved by feedback interactions between different cell types that express adhesion molecules and secrete cytokines. Disruption of these feedback mechanisms in cancer damages a tissue. When TGF-β signaling fails to control NF-κB activity in cancer cells, this has at least two potential effects: first, it enables the malignant tumor to persist in the presence of activated immune cells, and second, the cancer cell outlasts immune cells because it survives in the presence of apoptotic, and anti-inflammatory mediators.
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Synthetic inhibitors of Cdc25 could also be useful for the arrest of cell cycle and therefore be useful as antineoplastic and anticancer agents. In often cases, many human cancers possess the hyper-activated Cdk 4/6 activities. Given the observations of cyclin D-Cdk 4/6 functions, inhibition of Cdk 4/6 should result in preventing a malignant tumor from proliferating. Consequently, scientists have tried to invent the synthetic Cdk4/6 inhibitor as Cdk4/6 has been characterized to be a therapeutic target for anti-tumor effectiveness.
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Further clonal expansions have been observed in the stomach, bladder, colon, lung, hematopoietic (blood) cells, and prostate. These clonal expansions are important for at least two reasons. First, they generate a large target population of mutant cells and so increase the probability that the multiple mutations necessary to cause cancer will be acquired within that clone. Second, in at least one case, the size of the clone with loss of p53 has been associated with an increased risk of a pre-malignant tumor becoming cancerous.
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In 1989, he was diagnosed with a malignant tumor in his throat which Ray attributed to excessive smoking and drinking. His last film was Shock 'Em Dead which was filmed in mid-1990 appearing with Traci Lords and Troy Donahue. The same year he was interviewed and said about his cancer: > I regret that I don't have more control of my tongue and thoughts--because I > speak too frankly and too honestly, and this world is not meant for frank > and honest people. They don't mix.
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Early in 2002, Robinson was diagnosed with a malignant tumor in his sinuses, which was removed in April of the same year. He began performing again four days later in celebration of his 71st birthday at the Deep Blue Club. However, the cancer had already spread to the rest of his body, and his health deteriorated to the point of no recovery. On July 6, 2002, he was found dead in his car in Chicago with a self-inflicted gunshot wound to the head.
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The presence or absence of oxygen has a strong influence on ionizing radiation to cause cell death of tumour and normal cells. This is called the oxygen effect. Under hypoxic conditions it has been shown that cells obtain radioresistance through HIF-1 mediated mechanisms. To overcome this problem, radiation oncologists have developed powerful tools and approaches such as simultaneous integrated boost intensity-modulated radiation therapy (SIB-IMRT), which enables a booster dose of radiation to be delivered to small target fractions in a malignant tumor, hypoxia-selective cytotoxins/drugs, and HIF-1 inhibitors.
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Like many of the young protagonists of his films, Eloy de la iglesia became addicted to drugs such as heroin and he stopped making films for fifteen years. Claiming that his addiction to cinema was stronger than his drug problems, de la Iglesia eventually kicked his habit and resumed his career making Los novios bulgaros (The Bulgarian Lovers) (2003), a film based on the novel of the same title written by Eduardo Mendicutti. Stricken with kidney cancer, he died on March 24, 2006, age sixty two, after surgery to remove a malignant tumor.
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Jin Jing's parents are wage earners. Her father, Jin Jiansheng (Chinese: 金建生), is a sent-down youth who moved from Shanghai to Anhui during the Cultural Revolution, where he met and married Liu Huayao (Chinese: 刘华瑶). Jin was born in 1981, in Hefei, Anhui, She has a younger sister, Jin Renyu (Chinese: 金任钰). Jin had part of her right leg amputated in 1989 when she was in elementary school after a malignant tumor was found on her ankle and later underwent a year of chemotherapy.
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DFSP is a malignant tumor diagnosed with a biopsy, when a portion of the tumor is removed for examination. In order to ensure that enough tissue is removed to make an accurate diagnosis, the initial biopsy of a suspected DFSP is usually done with a core needle or a surgical incision. Clinical palpation is not entirely reliable for ascertaining the depth of a DFSP infiltration. Magnetic resonance imaging (MRI) is more sensitive addressing the depth of the invasion on some types of DFSP, particularly large or recurring tumors.
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While a member of the house of representative, Moffitt spearheaded a project to build a cancer treatment center in Florida. Moffitt had been diagnosed with a malignant tumor in his left knee at age 29, for which he did a tumor resection. It was this experience, along with the death of friends, Joseph Lumia, Judy Barnett and George Edgecomb, from cancer, that motivated Moffitt to lobby for a cancer treatment center in Tampa. He secured an initial $70-million via the Legislature for the commencement of the construction.
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For example, some previous diagnoses of stomach and small bowel leiomyosarcomas (malignant tumor of smooth muscle) would be reclassified as GISTs on the basis of immunohistochemical staining. All GIST tumors are now considered to have malignant potential, and no GIST tumor can be definitively classified as "benign". Hence, all GISTs are eligible for cancer staging in the AJCC (7th edition) / UICC.AJCC manual Nonetheless, different GISTs have different risk assessments of their tendency to recur or to metastasize, dependent on their site of origin, size, and number of mitotic figures.
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Despite having dated a number of women, professional baseball player Dong Chi-sung has never had a first love. "I always think it's love, but sooner or later I find out it's not..." Sure enough, his latest girlfriend dumps him, and then on the same day, he goes to the doctor and finds out he has a malignant tumor, with only three months to live. It's September now, so he won't even live to see the new year. With his mind in a tailspin, he goes to a friend's bar to drink away his pain.
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The order received approval from the diocese on 2 February 1942 as being only that of a "pious union". But difficulties with the order saw the local bishop order that the congregation be disbanded and forbidden to any form of apostolate until 1942 when the bishop approved a second form of its work. She fell ill once more in 1944 and later on 9 November 1944 was travelling to San Sebastián and fractured her leg in a car accident on a snow-covered road. Albero died on 27 August 1945 due to a malignant tumor.
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Lula in June 2015 On 29 October 2011, through the Syrian-Lebanese Hospital of São Paulo, it was announced that Lula had a malignant tumor in his larynx. He elected chemotherapy to counteract the tumor, and on 16 November, his press office released photos of his wife shaving his beard and hair, leaving him bald, although he retained his moustache. It was the first time that he had been seen without his beard since he left office. He was treated with radiation, and the cancer went into remission.
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Despite being assigned to take Mitsuki's soul, he is moved by her plight and transforms her into Full Moon. Takuto falls in love with Mitsuki as the series progresses, and he remembers his past as , the lead singer of ROUTE:L, the band that both Mitsuki's father and her doctor were in. After a malignant tumor in his throat took his voice, he attempted suicide and remained in a coma for the next two years. At the end of the series, Takuto saves Mitsuki's life, violating fate and his duty as a shinigami.
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However, in contrast to α-catenin, heightened β-catenin levels may be associated with carcinogenesis. In particular, abnormal interactions between epithelial cells and the extracellular matrix are associated with the over-expression of these β-catenins and their relationship with cadherins in some cancers. Stimulation of the Wnt/β-catenin pathway, and its role in promoting malignant tumor formations and metastases, has also been implicated in cancers. The role of catenin in epithelial-mesenchymal transition (or EMT) has also received a lot of recent attention for its contributions to cancer development.
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Nanobiotix is currently in the clinical stage of developing NBTXR3, a “radioenhancer” that uses nanotechnology to make cancer cells more receptive to radiotherapy. NBTXR3 is an aqueous suspension of crystalline metallic nanoparticles approximately 50 nanometers in diameter, designed for injection directly into a malignant tumor. When exposed to ionizing radiation, NBTXR3 amplifies the localized, intratumoral killing effect. Upon activation by a standard dose of radiation, they release free radicals that destroys cancer cells, whilst the surrounding healthy tissues are preserved and receive the same dose of radiation as in standard radiotherapy.
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Alexia González-Barros González (7 March 1971 - 5 December 1985) was a Spanish Roman Catholic child. González-Barros studied in school in Madrid and in her childhood received a papal blessing from Pope John Paul II during her trip to Rome. But in late 1984 she began feeling pains in her arm and back that led to a diagnosis two months later as being a malignant tumor in the vertebral column transforming into spinal cancer. Her siblings and friends remembered her for her piousness and her dedication to practicing holiness in all aspects of life.
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Debulking is the reduction of as much of the bulk (volume) of a tumour without the intention of a complete eradication. It is usually achieved by surgical removal. When performed for curative intent, it is a differente procedure, which is called surgical debulking of tumors is known as cytoreduction or cytoreductive surgery (CRS); "cytoreduction" refers to reducing the number of tumor cells. Debulking is used with curative intent in only some types of cancer, as generally partial removal of a malignant tumor is not a worthwhile intervention for curative purposes (because malignant cells left behind soon multiply and renew the threat).
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In molecular ultrasonography, the technique of acoustic radiation force (also used for shear wave elastography) is applied in order to literally push the targeted microbubbles towards microvessels wall; firstly demonstrated by Dr Paul Dayton in 1999. This allows maximization of binding to the malignant tumor; the targeted microbubbles being in more direct contact with cancerous biomolecules expressed at the inner surface of tumoral microvessels. At the stage of scientific preclinical research, the technique of acoustic radiation force was implemented as a prototype in clinical ultrasound systems and validated in vivo in 2D and 3D imaging modes.
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Incisional biopsies are obtained through diagnostic surgical procedures that remove part of a suspicious lesion, whereas excisional biopsies remove the entire lesion and are similar to therapeutic surgical resections. Excisional biopsies of skin lesions and gastrointestinal polyps are very common. The pathologist's interpretation of a biopsy is critical to establishing the diagnosis of a benign or malignant tumor, and can differentiate between different types and grades of cancer, as well as determining the activity of specific molecular pathways in the tumor. This information is important for estimating the patient's prognosis and for choosing the best treatment to administer.
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These lesions continued to attract and accumulate macrophages as the disease progressed, and cellular changes within the lesion culminated in a morphologically malignant tumor. Experimental evidence suggests that asbestos acts as a complete carcinogen with the development of mesothelioma occurring in sequential stages of initiation and promotion. The molecular mechanisms underlying the malignant transformation of normal mesothelial cells by asbestos fibers remain unclear despite the demonstration of its oncogenic capabilities (see next-but-one paragraph). However, complete in vitro transformation of normal human mesothelial cells to a malignant phenotype following exposure to asbestos fibers has not yet been achieved.
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Precautions are undertaken to eliminate the risks associated with transgenesis. Progress in genomics and proteomics should help us in identifying the cancer specific biomarkers and metabolic pathways for developing new strategies towards clinical trials of targeted and personalized gene therapy of cancer. By introducing the gene into a malignant tumor, the tumor would reduce in size and possibly disappear completely, provided all the individual cells have received a copy of the gene. When the DNA sample in the virus is taken from the patient's own healthy cells, the virus does not need to be able to differentiate between cancer cells and healthy ones.
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Cancer is a disease which is highly diverse not only its pathology, but in the initiation and progression from non-cancerous tissue to malignant tumor tissue . Cancer is considered to be stochastic in nature, in that there are many variables and probabilities that contribute to how a cell or tissue progresses from a state of non- cancerous, to cancerous, and eventually to metastasis. Cancer differs from many other diseases due to the uniquely long lifespan of the disease which contributes to the diversity of cancer cells both within a tumor and between related tumors in a host.
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The second most common malignant tumor in women is invasive cervical cancer (ICC) and more than 50% of all invasive cervical cancer (ICC) is caused by oncongenic human papillomavirus 16 (HPV16). Furthermore, cervix intraepithelial neoplasia (CIN) is primarily caused by oncogenic HPV16. As in many cases, the causative factor for cancer does not always take a direct route from infection to the development of cancer. Genomic methylation patterns have been associated with invasive cervical cancer. Within the HPV16L1 region, 14 tested CpG sites have significantly higher methylation in CIN3+ than in HPV16 genomes of women without CIN3.
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A surgical operation to remove a malignant tumor, 1817 In the 16th and 17th centuries, it became more acceptable for doctors to dissect bodies to discover the cause of death. The German professor Wilhelm Fabry believed that breast cancer was caused by a milk clot in a mammary duct. The Dutch professor Francois de la Boe Sylvius, a follower of Descartes, believed that all disease was the outcome of chemical processes, and that acidic lymph fluid was the cause of cancer. His contemporary Nicolaes Tulp believed that cancer was a poison that slowly spreads, and concluded that it was contagious.
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Large cell lung carcinoma with rhabdoid phenotype (LCLC-RP) is a rare histological form of lung cancer, currently classified as a variant of large cell lung carcinoma (LCLC). In order for a LCLC to be subclassified as the rhabdoid phenotype variant, at least 10% of the malignant tumor cells must contain distinctive structures composed of tangled intermediate filaments that displace the cell nucleus outward toward the cell membrane. The whorled eosinophilic inclusions in LCLC-RP cells give it a microscopic resemblance to malignant cells found in rhabdomyosarcoma (RMS), a rare neoplasm arising from transformed skeletal muscle. Despite their microscopic similarities, LCLC-RP is not associated with rhabdomyosarcoma.
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Now rendered ajanib (foreigners in Arabic), they could not vote, own land or any other kind of property, work for the government or marry legally. Furthermore, stateless Kurds had no passports, disabling them to travel, were not admitted to public hospitals and were not able to apply for food subsidies. According to several researchers and organizations, the number of stateless Syrian Kurds has increased since 1962 to over 300.000 stateless Kurds, because all children of stateless Kurdish fathers inherit the same status. This discriminatory policy towards the Kurds was partly influenced by Mohammed Talib Hilal, chief of police in the 1960s, who referred to the Kurds as a “malignant tumor” .
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Another common bone graft, which is more substantial than those used for dental implants, is of the fibular shaft. After the segment of the fibular shaft has been removed normal activities such as running and jumping are permitted on the leg with the bone deficit. The grafted, vascularized fibulas have been used to restore skeletal integrity to long bones of limbs in which congenital bone defects exist and to replace segments of bone after trauma or malignant tumor invasion. The periosteum and nutrient artery are generally removed with the piece of bone so that the graft will remain alive and grow when transplanted into the new host site.
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The man identifies the presence of a malignant tumor and the woman, unable to deal with this confirmation of her worst fears, faints. The man catches her to keep her from injury but suffers burns to his arms as she discharges into him. When the woman regains consciousness, the man tells her that she has been cured of her cancer. She begins to thank him, but he suddenly becomes angry saying that he does not want to hear speeches about how he owes it to the world to share his cure and warns her against telling anyone or he will take legal action to save himself from accusations of medical malpractice.
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The reactivity of magnetic particles depends on their spin state. The experimental data was received about correlation between the frequency of electromagnetic field radiation with magnetic properties and quantity paramagnetic centres of complex. It is possible to control the kinetics of free-radical reactions by external magnetic fields and modulate the level of oxidative stress (local toxicity) in malignant tumor. Cancer cells are then particularly vulnerable to an oxidative assault and induction of high levels of oxidative stress locally in tumor tissue, that has the potential to destroy or arrest the growth of cancer cells and can be thought as therapeutic strategy against cancer.
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Excisional biopsies of skin lesions and gastrointestinal polyps are very common. The pathologist's interpretation of a biopsy is critical to establishing the diagnosis of a benign or malignant tumor, and can differentiate between different types and grades of cancer, as well as determining the activity of specific molecular pathways in the tumor. Surgical resection specimens are obtained by the therapeutic surgical removal of an entire diseased area or organ (and occasionally multiple organs). These procedures are often intended as definitive surgical treatment of a disease in which the diagnosis is already known or strongly suspected, but pathological analysis of these specimens remains important in confirming the previous diagnosis.
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Rodriguez was born in Houston, Texas. In 1985 a low speed motorcycle accident revealed a malignant tumor in his right hip resulting in resection, removal, and reconstruction that ultimately failed ending in eventual amputation of his right hip & leg or hip-disarticulation/semi-hemipelvectomy in April, 1992. In 2002 and 2003 respectively he won 3 bronze medals in three different world cups in men's category A foil in Austin, Texas, United States; Madrid, Spain; and Warsaw, Poland. In 2010 he was a gold medalist at the North American Cup for sabre and in 2011 won another gold for foil at the Parapan American Games.
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Lymphoepithelioma-like carcinoma (LELC) is a medical term referring to a histological variant of malignant tumor arising from the uncontrolled mitosis of transformed cells originating in epithelial tissue (or in cells that display epithelial characteristics) that bear microscopic resemblance to lymphoepithelioma (nasopharyngeal carcinoma). There is considerable variation in the classification of LELC—while it is perhaps most commonly considered a subtype of squamous cell carcinoma, it can also be classified as a form of large cell carcinoma (i.e. when occurring in the lung), and can be considered as a separate, unique entity. In most anatomical sites, many cases are associated with the Epstein-Barr virus.
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Hexokinases I and II can associate physically to the outer surface of the external membrane of mitochondria through specific binding to a porin, or voltage dependent anion channel. This association confers hexokinase direct access to ATP generated by mitochondria, which is one of the two substrates of hexokinase. Mitochondrial hexokinase is highly elevated in rapidly growing malignant tumor cells, with levels up to 200 times higher than normal tissues. Mitochondrially bound hexokinase has been demonstrated to be the driving force for the extremely high glycolytic rates that take place aerobically in tumor cells (the so-called Warburg effect described by Otto Heinrich Warburg in 1930).
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The unanimous decision of the convent's leadership saw her made abbess on 12 August 1920 and she held that post until her death. In 1923 she began the circulation of the newsletter "Dalle Api alle Rose" (first edition published 22 May 1923) in order to promote the almost unknown chapel that contained the remains of Rita of Cascia and desired bringing people to God through the saint she admired. Fasce suffered from a malignant tumor on her right breast and had to undergo two operations on it. She referred to her tumor as her "treasure" that was the most beautiful gift that Jesus Christ had given her.
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Small-cell lung carcinoma can occur in combination with a wide variety of other histological variants of lung cancer, including extremely complex malignant tissue admixtures. When it is found with one or more differentiated forms of lung cancer, such as squamous cell carcinoma or adenocarcinoma, the malignant tumor is then diagnosed and classified as a combined small cell lung carcinoma (c-SCLC). C-SCLC is the only currently recognized subtype of SCLC. Although combined small-cell lung carcinoma is currently staged and treated similarly to "pure" small-cell carcinoma of the lung, recent research suggests surgery might improve outcomes in very early stages of this tumor type.
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Rous was involved in the discovery of the role of viruses in the transmission of certain types of cancer. On October 13, 1966, he was awarded a Nobel Prize in Physiology or Medicine for his work. In 1911, as a pathologist, he made his seminal observation that a malignant tumor (specifically, a sarcoma) growing on a domestic chicken could be transferred to another fowl simply by exposing the healthy bird to a cell-free filtrate. This finding, that cancer could be transmitted by a virus (now known as the Rous sarcoma virus, a retrovirus), was widely discredited by most of the field's experts at that time.
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He organized more than 200 of the Saint Rita Workshops which attracted poor people to make clothing that the poor could afford. He was often seen walking down the streets of São Paulo to pastoral visits though even as he aged and his strength waned and his vision grew dim he still made this a practice. He had his sight diminishing due to cataracts which he removed but had his eyes covered for a little while despite his evident frustration at being unable to do things. He was diagnosed with cancer in January 1983 and underwent an operation to remove a malignant tumor in the pancreas but the cancer continued to spread at a rapid pace.
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After an international campaign that included his designation as an Amnesty International prisoner of conscience and a request by France Libertés, the organization founded by former French first lady Danielle Mitterrand, Arcos was released in 1995. A few weeks after his release, Arcos was diagnosed with a malignant tumor in the rectum, for which he had previously been denied medicine and treatment in prison. After a Cuban doctor was fired from his post for treating Arocs, he traveled to Miami for further care. In 1996 he testified before the UN Human Rights Commission in Geneva, Switzerland, and in 1997 was awarded the first Human Rights Award given by the Spanish-Cuban Foundation (Fundación Hispano-Cubana).
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370 BC) described several kinds of cancer, referring to them with the Greek word καρκίνος karkinos (crab or crayfish). This name comes from the appearance of the cut surface of a solid malignant tumor, with "the veins stretched on all sides as the animal the crab has its feet, whence it derives its name".Paul of Aegina, 7th Century AD, quoted in Referenced from Michael Shimkin, Contrary to Nature, Washington, DC: Superintendent of Document, DHEW Publication No. (NIH) 79–720, p. 35. Galen stated that "cancer of the breast is so called because of the fancied resemblance to a crab given by the lateral prolongations of the tumor and the adjacent distended veins".
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Khrushchev (right) with U.S. Vice President Richard Nixon, 1959 Khrushchev sought to find a lasting solution to the problem of a divided Germany and of the enclave of West Berlin deep within East German territory. In November 1958, calling West Berlin a "malignant tumor", he gave the United States, United Kingdom and France six months to conclude a peace treaty with both German states and the Soviet Union. If one was not signed, Khrushchev stated, the Soviet Union would conclude a peace treaty with East Germany. This would leave East Germany, which was not a party to treaties giving the Western Powers access to Berlin, in control of the routes to the city.
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Lumpectomy (sometimes known as a tylectomy, partial mastectomy, breast segmental resection or breast wide local excision) is a surgical removal of a discrete portion or "lump" of breast tissue, usually in the treatment of a malignant tumor or breast cancer. It is considered a viable breast conservation therapy, as the amount of tissue removed is limited compared to a full-breast mastectomy, and thus may have physical and emotional advantages over more disfiguring treatment. Sometimes a lumpectomy may be used to either confirm or rule out that cancer has actually been detected. A lumpectomy is usually recommended to patients whose cancer has been detected early and who do not have enlarged tumors.
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The inhibition of COX-2 is paramount for the anti-inflammatory and analgesic function of the selective COX-2 inhibitor celecoxib. However, with regard to this drug's promise for the therapy of advanced cancers, it is unclear whether the inhibition of COX-2 plays a dominant role, and this has become a controversial and intensely researched issue. In recent years, several additional intracellular components (besides COX-2) were discovered that appear to be important for mediating the anticancer effects of celecoxib in the absence of COX-2. Moreover, a recent study with various malignant tumor cells showed that celecoxib could inhibit the growth of these cells, even though some of these cancer cells didn't even contain COX-2.
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Certainly, the inhibition of COX-2 is paramount for the anti-inflammatory and analgesic function of celecoxib. However, whether inhibition of COX-2 also plays a dominant role in this drug's anticancer effects is unclear. For example, a recent study with malignant tumor cells showed celecoxib could inhibit the growth of these cells in vitro, but COX-2 played no role in this outcome; even more strikingly, the anticancer effects of celecoxib were also obtained with the use of cancer cell types that do not even contain COX-2. Additional support for the idea that other targets besides COX-2 are important for celecoxib's anticancer effects has come from studies with chemically modified versions of celecoxib.
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Winovich works with Tammi Carr and The ChadTough Foundation to raise awareness of and money for research on diffuse intrinsic pontine glioma (DIPG), an inoperable malignant tumor of the brainstem. (Carr's son, Chad, the grandson of former Michigan head football coach Lloyd Carr, died of DIPG in November 2015 at age 5.) Since teaming up with The ChadTough Foundation prior to the 2017 Michigan football season, Winovich has worked to increase awareness about DIPG. In December 2017, Winovich and several of his teammates and coaches dyed their hair orange for the 2018 Outback Bowl in order to raise over $200,000 for the ChadTough Foundation. He has also participated in Dancing with the Michigan Stars, which raised over $143,000.
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The future of contrast ultrasonography is in molecular imaging with potential clinical applications expected in cancer screening to detect malignant tumors at their earliest stage of appearance. Molecular ultrasonography (or ultrasound molecular imaging) uses targeted microbubbles originally designed by Dr Alexander Klibanov in 1997; such targeted microbubbles specifically bind or adhere to tumoral microvessels by targeting biomolecular cancer expression (overexpression of certain biomolecules occurs during neo-angiogenesis or inflammation processes in malignant tumors). As a result, a few minutes after their injection in blood circulation, the targeted microbubbles accumulate in the malignant tumor; facilitating its localization in a unique ultrasound contrast image. In 2013, the very first exploratory clinical trial in humans for prostate cancer was completed at Amsterdam in the Netherlands by Dr Hessel Wijkstra.
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Poster advertising Pausch's lecture "Really Achieving Your Childhood Dreams" (also referred to as "The Last Lecture") was a lecture given by Carnegie Mellon University computer science professor Randy Pausch on September 18, 2007, that received a large amount of media coverage, and was the basis for The Last Lecture, a New York Times best-selling book co-authored with Wall Street Journal reporter Jeffrey Zaslow. Pausch had been diagnosed with pancreatic cancer in September 2006. On September 19, 2006, Pausch underwent a pancreaticoduodenectomy to remove the malignant tumor from his pancreas. In August 2007, after doctors discovered that the cancer had recurred, Pausch was given a terminal diagnosis and was told to expect a remaining three to six months of good health.
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CTLM is a non-invasive practical system that uses near- infrared laser light propagation through the tissue to assess its optical properties. It is based on two basic principles: different tissue components have unique scattering and absorption characteristics for each wavelength and the malignant tumor growth requires neovascularization to grow beyond 2 mm in size. In new forming tumors, the blood flow increases and the CTLM then looks for high hemoglobin concentration (angiogenesis) in the breast that are structurally and functionally abnormal, and to detect neovascularization, which may be hidden in mammography images especially in dense breast. This neovascularization, which results in a greater volume of hemoglobin in a confined area, can be visualized using absorption measurements of laser light.
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Dysgerminoma accounts for 35% of ovarian cancer in young women and is the most likely germ cell tumor to metastasize to the lymph nodes; nodal metastases occur in 25–30% of cases. These tumors may have mutations in the KIT gene, a mutation known for its role in gastrointestinal stromal tumor. People with an XY karyotype and ovaries (gonadal dysgenesis) or an X,0 karyotype and ovaries (Turner syndrome) who develop a unilateral dysgerminoma are at risk for a gonadoblastoma in the other ovary, and in this case, both ovaries are usually removed when a unilateral dysgerminoma is discovered to avoid the risk of another malignant tumor. Gonadoblastomas in people with Swyer or Turner syndrome become malignant in approximately 40% of cases.
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Neutron cross section of boron (top curve is for 10B and bottom curve for 11B) Enriched boron or 10B is used in both radiation shielding and is the primary nuclide used in neutron capture therapy of cancer. In the latter ("boron neutron capture therapy" or BNCT), a compound containing 10B is incorporated into a pharmaceutical which is selectively taken up by a malignant tumor and tissues near it. The patient is then treated with a beam of low energy neutrons at a relatively low neutron radiation dose. The neutrons, however, trigger energetic and short-range secondary alpha particle and lithium-7 heavy ion radiation that are products of the boron + neutron nuclear reaction, and this ion radiation additionally bombards the tumor, especially from inside the tumor cells.
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In subsequent issues, Adam joins supervillain Johnny Sorrow's Injustice Society after Sorrow removes a malignant tumor from Adam's brain. He is sent to battle Wildcat, and easily defeats him, showing how easily he could kill him by taking him about 25,000 feet above the ground—just high enough for them to talk while unable to go any higher without the human Wildcat freezing or suffocating—explaining the different ways he could kill him, and asking what he will give for his life. He shows him the Rock of Eternity where Sorrow has turned Shazam to stone with his cursed face that usually kills those that see him, also making contact with the Spectre, who provides them with additional information. Adam soon betrays Sorrow, and he and the JSA defeat the Injustice Society.
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For a martyr, the Pope has only to make a declaration of martyrdom, which is a certification that the Venerable died voluntarily as a witness of the Faith or in an act of heroic charity for others. The Archbishop of Westminster, then Cardinal William Godfrey, sent a description of 24 seemingly miraculous cases to the Sacred Congregation. Out of 20 candidate cases for recognition as answered prayers, the alleged cure of a young mother from a malignant tumor was selected as the clearest case. In light of the fact that Thomas More and John Fisher, belonging to the same group of Martyrs, had been canonized with a dispensation from miracles, Pope Paul VI, after discussions with the Sacred Congregation for the Causes of Saints, considered that it was possible to proceed with the Canonization on the basis of one miracle.
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It has been suggested that Dutch Old Master Rembrandt may have been stereoblind, which would have aided him in flattening what he saw for the production of 2D works.Marmor M. F., Shaikh S., Livingstone M. S., Conway B. R., Rembrandt (van Rijn) Scientists have suggested that more artists seem to have stereoblindness when compared with a sample of people with stereo-acuteness (normal stereo vision). New York Times: A defect that may lead to a masterpiece (June 13, 2011) British neurologist Oliver Sacks lost his stereoscopic vision in 2009 due to a malignant tumor in his right eye and had no remaining vision in that eye."The Man Who Forgot How to Read and Other Stories", BBC accessed 30 June 2011 His loss of stereo vision was recounted in his book The Mind's Eye, published in October 2010.
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He has published over thirty peer-reviewed original research articles (Google Scholar) in the specialty of mitochondrial bioenergetics and molecular biology. His largest contribution to biochemistry and cell biology was to demonstrate that the mitochondrial hexokinase is the enzyme responsible for driving the high rates of glycolysis that occur under aerobic conditions characteristic of rapidly growing malignant tumor cells. Since then, aerobic glycolysis by malignant tumors is utilized clinically to diagnose and monitor treatment responses of cancers by imaging uptake of 2-18F-2-deoxyglucose (a radioactive modified hexokinase substrate) with positron emission tomography (PET). In 2005, he published a research article that demonstrates that the functional association of glucokinase (a hexokinase isoform) to mitochondrial metabolism and intracellular signaling of apoptosis in normal liver is actually not mediated by a physical association of this enzyme with mitochondria or either their inner membrane or outer membrane as proposed by others.
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On 5 March 2011, after undergoing a routine check-up due to back problems, Roqué was diagnosed with pelvic cancer, undergoing surgery to excise a malignant tumor the following day. Betis' fan clubs raised funds for his treatment, while Carles Puyol, of the same province, financed €30,000 for specialist private treatment. On 24 June 2012, after just over a year of illness, Roqué lost his battle against cancer and died, two weeks before his 24th birthday. His death prompted a series of tributes on Twitter, including from several international players competing in UEFA Euro 2012, and on 1 July, after the final of the continental competition, Spain goalkeeper Pepe Reina (his former Liverpool teammate) wore a Betis shirt featuring Roqué's name during the players' victory lap of the Olympic Stadium in Kiev; also, Cesc Fàbregas wore a shirt with the names of Roqué, Dani Jarque, Manolo Preciado and Antonio Puerta.
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The results of numerous experimental and clinical studies of malignant neoplasms have indicated that invasive growth and metastasis are the main manifestations of tumor progression, which represent two closely related processes. A malignant tumor is characterized by the possibility to implement such a biological phenomenon as the metastatic cascade that is a unique multi-stage “program” where cell invasion is a trigger and a key factor for further cancer progression and metastasis in distant organs and tissues. Massive metastatic lesions lead to the development of severe organ failure and, therefore, a patient’s death. The range between “end” points of a complex invasive metastatic process –invasion of the primary tumor into surrounding tissues and the formation of metastatic foci –comprises several stages, the passage of which is strictly necessary for the successful development and subsequent progression of tumor growth: intravasation, survival and presence in the systemic circulation, extravasation with subsequent colonization of organs by tumor cells, and the formation of clinically detectable metastasis.
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In 1929, the Fascist regime briefly gained what was in effect a blessing of the Catholic Church after the regime signed a concordat with the Church, known as the Lateran Treaty, which gave the papacy state sovereignty and financial compensation for the seizure of Church lands by the liberal state in the nineteenth century, but within two years the Church had renounced Fascism in the Encyclical Non Abbiamo Bisogno as a "pagan idolotry of the state" which teaches "hatred, violence and irreverence". Not long after signing the agreement, by Mussolini's own confession, the Church had threatened to have him "excommunicated", in part because of his intractable nature, but also because he had "confiscated more issues of Catholic newspapers in the next three months than in the previous seven years”.Denis Mack Smith, Mussolini, New York: Vintage Books, 1983, p. 162 By the late 1930s, Mussolini became more vocal in his anti-clerical rhetoric, repeatedly denouncing the Catholic Church and discussing ways to depose the pope. He took the position that the “papacy was a malignant tumor in the body of Italy and must 'be rooted out once and for all,’ because there was no room in Rome for both the Pope and himself".
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