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"foci" Definitions
  1. a plural of focus.

721 Sentences With "foci"

How to use foci in a sentence? Find typical usage patterns (collocations)/phrases/context for "foci" and check conjugation/comparative form for "foci". Mastering all the usages of "foci" from sentence examples published by news publications.

Their foci include addressing environmental sustainability, racial and gender equity, economic development concerns, etc.
FOCI was created with machine learning and cognitive biometrics after two decades of research.
Join thousands of people regaining unadulterated concentration by picking up FOCI, now on sale for $69.
The World Health Organization says the coronavirus outbreak is not a pandemic, but an epidemic with multiple foci.
TL;DR: Get your attention span back on track with the FOCI wearable for $69, a 42% savings during this sale.
Seemingly oblivious that he's the foci of a very important pop culture subgenre, Thompson is not getting a warm welcome for this post.
The majority of AF points are centered in the frame, allowing the joystick to become the perfect precision tool for picking your foci.
It's been almost a decade since anyone watched TRL and since then everything about its primary foci—music videos, celebrity culture, TV consumption—has changed.
While her opponents maintained singular foci, she was more like the Chinese-Indian-burger joint, equally attentive to a grab bag of (critically important) issues.
FOCI is a focus-boosting wearable that clips to your waist and keeps tabs on your cognitive state, alerting you when your focus is waning.
Other aspects of Google's business, such as data privacy issues or its licensing policies for the Android operating system, aren't foci of the investigation, for now.
SEO is one of our core foci, and it is shocking how little supply there is of SEO talent relative to the size of this channel.
The outbreak did not constitute a pandemic but an epidemic with "multiple foci," WHO director of global hazard preparedness Sylvie Briand told a news conference in Geneva.
The next best thing to do is find a way to become more focused, and the FOCI has a science-backed approach on how to accomplish that.
In the early days, the service only operated in a few cities, included a hefty surcharge, and dispatched sleek Town Cars and limos instead of Foci and Priui.
I've seen so many people this week talk about games as self care, or games as foci for thinking about tough personal and social issues, or game-making as therapeutic practice.
Although I agree with Gingrich that the "Starman" photos are cool, they hardly will provide the impetus for a major shift in educational foci and career paths for a new generation of young people.
Spoilers ahead for Game of Thrones season 7, episode 2 One of the bigger foci in tonight's episode was on Jorah Mormont's developing greyscale infection, which was teased last week in one of our favorite scenes.
By analyzing a density plot of the transformed trajectories, we found the vast majority are fully contained within an ellipse that has the same shape independent of the scale, with the start and endpoints as foci.
While most black metal bands shy away from politics (or, as part of an outcast minority, embrace the far right), Book of Sand veers sharply—and vocally—left, citing anarchism, feminism, anti-racism, and veganism as its core lyrical foci.
Consider how the principal foci of TV seemed to shift when he became president—figuratively bullhorning his way into TV's domestic interior in a way that has clogged the thematic daring on a number of shows across network, cable, and streaming platforms.
The episode, much like life, keeps moving to the real foci: Issa (Rae's fictional self), who continues to flounder at the education nonprofit she works for, and Lawrence (Jay Ellis), who's making his way through a post-breakup haze and into newfound bachelorhood.
Have a wander below: Karl Meyer, 'Foci' (22017) Karl Meyer, 'Foci' (20173) Britt Mikkelsen, 'Ocean Lace' (22017) Stephen Marr, 'Under One Sky' (22017) Stephen Marr, 'Under One Sky' (22017) James Dive, 'What a Tasty Looking Burger' (2017) Elyssa Sykes-Smith, 'Stagnation' (2017) Harrie Fasher, 'The Last Charge' (2017) Harrie Fasher, 'The Last Charge' (2017) John Petrie, 'Space' (2017) Winner, David Ball 'Orb' (2017) Simon Hodgson, 'Melencolia' (20173) Xia Hang, 'Rangerer' (2017) Lucy Barker, 'Sea Through' (2017) Fatih Semiz, 'Curious Dream of an Architect' (2017) Kathy Allam, 'Plastic Paradise' (2017) Linton Meagher, 'Look out for Me' (2017) Yoshio Nitta, 'I Put a Moon on the Table But it Has a Hole and is Lacking' (2017) Sonia Payes, 'Littoral Echo' (2017) Tetsuro Yamasaki, 'Circle on the Earth' (2017) Tango Conway & Amelia Skelton, 'White Wash (2017) Jock Clutterbuck, 'Song of the Aisors' (2017) April Pine.
These points of intersection are the defined to be the foci of C. In other words, a point P is a focus if both PI and PJ are tangent to C. When C is a real curve, only the intersections of conjugate pairs are real, so there are m in a real foci and m2−m imaginary foci. When C is a conic, the real foci defined this way are exactly the foci which can be used in the geometric construction of C.
Zinder and Maradi are two foci of leatherwork and trade.
The chords of an ellipse which are perpendicular to the major axis and pass through one of its foci are called the latera recta of the ellipse. The interfocal segment connects the two foci.
In third-order astigmatism, the sagittal and transverse rays form foci at different distances along the optic axis. These foci are called the sagittal focus and the transverse focus, respectively. In the presence of astigmatism, an off-axis point on the object is not sharply imaged by the optical system. Instead, sharp lines are formed at the sagittal and transverse foci.
This aggregation of DDR factors and concentration of phosphorylated and ubiquitinated histones is called a DNA damage foci or ionizing radiation-induced foci and the main role of MDC1 is to coordinate the creation of DNA damage foci. This protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage.
Point F is a focus point for the red ellipse, green parabola and blue hyperbola. In geometry, focuses or foci (, ), singular focus, are special points with reference to which any of a variety of curves is constructed. For example, one or two foci can be used in defining conic sections, the four types of which are the circle, ellipse, parabola, and hyperbola. In addition, two foci are used to define the Cassini oval and the Cartesian oval, and more than two foci are used in defining an n-ellipse.
The M115 was shown to establish 100,000 foci of infection over a area.
Rosai (2004).Rosai and Ackerman's Surgical Pathology. Philadelphia, Mosby, p.1128. Hyperchromatic and bizarre nuclei in neuroblasts and ganglion cells in undifferentiated or poorly differentiated foci are far too pathognomonic, although anaplastic expressions can be found in differentiating foci alike.
As pregnancy progresses, Gata 5 is involved in the specification of the heart tissue that becomes the ventricles. Problems can arise when Gata5 is overexpressed. This overexpression can lead to ectopic foci. Ectopic foci are also known as ectopic pacemakers.
Aberrant crypt foci (ACF) are clusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before colorectal polyps and are one of the earliest changes seen in the colon that may lead to cancer. ACF are, as opposed to normal epithelial cells, apoptosis resistant. When looking for aberrant crypt foci with microscopy, methylene blue is used as a staining agent.
The group's main foci are the prediction and monitoring of worldwide weather and climate extremes.
Di Nicola's career has shown several foci, examining children, families and culture in various combinations.
Materials, Drama, Visual Arts). The final aspect was Foci. Foci's are where students can enhance a deeper understanding/knowledge into a particular interest of two subjects (e.g. A "Board Gaming" foci can focus on the Mathematical and Social Science sides of "gaming", and interest "gaming" students.
An incident laser beam is deflected by grooved diffraction pattern into axial diffraction orders along its optical axis. The foci appear around the far field position. With an additional focusing lens, foci from multifocal lens will appear at certain distances from the focal point of the lens.
The foci of an ellipse (purple crosses) are at intersects of the major axis (red) and a circle (cyan) of radius equal to the semi-major axis (blue), centred on an end of the minor axis (grey) An ellipse can be defined as the locus of points for each of which the sum of the distances to two given foci is a constant. A circle is the special case of an ellipse in which the two foci coincide with each other. Thus, a circle can be more simply defined as the locus of points each of which is a fixed distance from a single given focus. A circle can also be defined as the circle of Apollonius, in terms of two different foci, as the set of points having a fixed ratio of distances to the two foci.
They finally relocate to N/M/R where they form the foci at the site of damage.
The revolution had two main foci in Macedonia, one was on Olympus, and the other in Vourinos.
A parabola is a limiting case of an ellipse in which one of the foci is a point at infinity. A hyperbola can be defined as the locus of points for each of which the absolute value of the difference between the distances to two given foci is a constant.
Sometimes unusual activity of the red blood cells, white blood cells, or platelets is seen.The liver is often moderately enlarged, with foci of extramedullary hematopoiesis. Microscopically, lymph nodes also contain foci of hematopoiesis, but these are insufficient to cause enlargement. There are also reports of hematopoiesis taking place in the lungs.
Among the foci of the study are the impact of Ebola and interactions with other species (chimpanzees and humans).
Together with senescence-associated heterochromatin foci (SAHF), DNA-SCARS are one of the most prevalent nuclear markers of cellular senescence.
A line segment can be viewed as a degenerate case of an ellipse, in which the semiminor axis goes to zero, the foci go to the endpoints, and the eccentricity goes to one. A standard definition of an ellipse is the set of points for which the sum of a point's distances to two foci is a constant; if this constant equals the distance between the foci, the line segment is the result. A complete orbit of this ellipse traverses the line segment twice. As a degenerate orbit, this is a radial elliptic trajectory.
In Prehistory of Oklahoma pp. 45–63: Academic Press. & Charles L. Rohrbaugh 1984, Arkansas Valley Caddoan: Fort Coffee and Neosho Foci.
The concerto is one of the main foci of the 1996 film Shine, based on the life of pianist David Helfgott.
Puente had four foci during his term as APA president: improving governance, membership engagement, psychology's international presence, and the APA Convention.
The organic structure, as expounded by Jon Franklin, is composed at its most basic level of visual imagery that provides a cinematic feel. These are linked into "foci" that detail an action, which are in turn linked by "transitions in time, mood, subject and character". A typical sequence of foci may be complication, development, and resolution.
Multiple instruments are available on standby, mounted at unusually high weight-capacity Nasmyth foci and two lower capacity bent-Cassegrain foci. Switching is accomplished within a few minutes by rotating the 45° tertiary mirror. The pointing of this mirror is adjusted at high speed to prevent image blur from vibrations induced by wind-shake of the telescope structure.
Such foci are sharply circumscribed, firm, gray-white to yellow areas that have a variable amount of central caseation and peripheral fibrosis.
142–146 With respect to the beginnings of projective geometry, Kepler introduced the idea of continuous change of a mathematical entity in this work. He argued that if a focus of a conic section were allowed to move along the line joining the foci, the geometric form would morph or degenerate, one into another. In this way, an ellipse becomes a parabola when a focus moves toward infinity, and when two foci of an ellipse merge into one another, a circle is formed. As the foci of a hyperbola merge into one another, the hyperbola becomes a pair of straight lines.
A Cartesian oval is the set of points for each of which the weighted sum of the distances to two given foci is a constant. If the weights are equal, the special case of an ellipse results. A Cassini oval is the set of points for each of which the product of the distances to two given foci is a constant.
In the theory, the focus of infection might lead to secondary infections at sites particularly susceptible to such microbial species or toxin. Commonly alleged foci were diverse—appendix, urinary bladder, gall bladder, kidney, liver, prostate, and nasal sinuses—but most commonly were oral. Besides dental decay and infected tonsils, both dental restorations and especially endodontically treated teeth were blamed as foci.
Once a week, magnetoencephalography is dedicated to serving the community by providing clinical and diagnostic services, such as localization of epileptic foci, via BrainMap.
His particular research foci are aerobatic control of unmanned aerial vehicles, multi-agent operations, including air traffic control systems and aerospace software system certification.
The Lanzou brand uses Citrus (ju hong). The Lanzhou Foci Min Shan brand and the Plum Flower brand do not, but use Ginger (sheng jiang).
The 5 year survival is 49-69%. Atypical carcinoid tumors have increased mitotic activity (2-10 per 10 HPF), nuclear pleomorphism or foci of necrosis.
It is a particular case of the first family described in #2. # The Apollonian circles are two families of mutually orthogonal circles. The first family consists of the circles with all possible distance ratios to two fixed foci (the same circles as in #1), whereas the second family consists of all possible circles that pass through both foci. These circles form the basis of bipolar coordinates.
These heteroplatic elements may include hyaline cartilage, rhabdomyoblasts, and neuroglial tissue. Sarcomatous elements may be seen in malignant tumors. Foci of dystrophic calcifications may be present.
One of Kroll's research foci has to do with language selection in bilingual speech. She discovered that when one language is spoken, both languages are active.
Thus, if BCF2 is a right-angle triangle with integral sides, the separation of the foci, linear eccentricity, minor axis and major axis are all also integers.
In addition, BDBT was shown to rhythmically accumulate in PER and DBT-dependent cytosolic foci in the fly eye. Price's lab established BDBT as a mediator of DBT's effects on PER, which regulates PER nuclear accumulation in discrete foci In photoreceptors. In 2015, Price's lab noted that DBT proteins lacking a nuclear localization signal (NLS) failed to interact with BDBT, suggesting that this interaction is mediated by the NLS.
In vertebrate cells, replication sites concentrate into positions called replication foci. Replication sites can be detected by immunostaining daughter strands and replication enzymes and monitoring GFP-tagged replication factors. By these methods it is found that replication foci of varying size and positions appear in S phase of cell division and their number per nucleus is far smaller than the number of genomic replication forks. P. Heun et al.
The others would frequently pernoctate and, as with the other fellows, their rooms were the natural and welcome foci of enormously diverse social, literary, scientific and musical activities.
In physics, a quantum mirage is a peculiar result in quantum chaos. Every system of quantum dynamical billiards will exhibit an effect called scarring, where the quantum probability density shows traces of the paths a classical billiard ball would take. For an elliptical arena, the scarring is particularly pronounced at the foci, as this is the region where many classical trajectories converge. The scars at the foci are colloquially referred to as the "quantum mirage".
Distance dependence of adolescent friendships. Social Networks, 34, 18-31. Through the completion of their study, the researchers concluded that social foci that provide constant and continual interaction among the same participants yielded a strong effect on friendship formation. The most notable social foci included attending the same school or one's own neighborhood, as these are both settings in which one is within a close proximity to the same people on numerous occasions.
The cause is unknown, but this condition has been associated with testicular cancer in a small group of individuals, cryptorchidism, mumps, infertility and intraepithelial germ cell neoplasia. Classic testicular microlithiasis is defined as five or more echogenic foci per view in either or both testes, and limited testicular microlithiasis defined as one or more echogenic foci that do not satisfy the criteria for classic testicular microlithiasis. In 80% of cases, both testicles are affected.
The fibrosing pattern displays interstitial fibrosis with various inflammation levels. Both patterns are uniform and lack the prominent fibroblastic foci that are found in other types of idiopathic interstitial pneumonia.
Adaptive optics, especially wavefront-coding spatial light modulators, are frequently used in optical trapping applications to multiplex and dynamically reconfigure laser foci that are used to micro- manipulate biological specimens.
The Orr Focus is distinctive from other Oneota Foci mainly in terms of the pottery which is based on rectilinear (instead of curvilinear) decoration and frequent notching on the lip.
GalR exists in only one to two foci in cells and can self- assemble into large ordered structures. Therefore, it appears that DNA-bound GalR multimerizes to form long-distance interactions.
In the summer of 1967, Monthly Review published an English translation of Régis Debray's Revolution In The Revolution?, which argued in support of Che Guevara's "foci theory of revolution". Near the end of the summer, a New York SDS regional organizer named Halliwell appeared at one meeting to make the case for applying Debray's theory of "mobile tactics" to Columbia University conditions, with Columbia SDS acting as the non-violent equivalent of Che's "guerrilla foci group". According to Halliwell's analogy, the mass of Columbia students, like the mass of Latin American peasants, could only be aroused if Columbia SDS developed the capacity to act on an off-campus level as a mobile non-violent guerrilla foci at anti-war demonstrations.
B. turicatae is predominant in the Southwestern United States. Endemic foci for B. turicatae occur in Texas and Florida, where clinical isolates have been obtained from sick dogs, suggesting a role for wild canids in the maintenance of the spirochaetes in nature. O. turicata has also been reported to be distributed in Mexico and Central and South America, yet given the absence of Latin American isolates for B. turicatae, the identification of endemic foci is unclear.
A Simon focus is a tuberculosis (TB) nodule that can form in the apex of the lung when a primary TB infection elsewhere in the body spreads to the lung apex via the bloodstream. Simon focus nodules are often calcified. The initial lesion is usually a small focus of consolidation, less than 2cm in diameter and located within 1 to 2 cm of the apical pleura. In adolescence, Simon foci may become reactivated and develop into Assmann foci.
Some of the cultures designated as Upper Mississippian are the Oneota complex with its various foci. The Fisher and Huber pottery types are the most common encountered during the Griesmer excavations. Fisher and Huber are either considered foci of the Oneota complex by archaeologists, or closely related to Oneota. Charles Faulkner in 1972 developed a typology of pottery descriptions for these two types based on specimens from the Griesmer site and comparisons with other nearby sites with similar pottery.
Pencils of confocal ellipses and hyperbolas In geometry, two conic sections are called confocal, if they have the same foci. Because ellipses and hyperbolas possess two foci, there are confocal ellipses, confocal hyperbolas and confocal mixtures of ellipses and hyperbolas. In the mixture of confocal ellipses and hyperbolas, any ellipse intersects any hyperbola orthogonally (at right angles). Parabolas possess only one focus, so, by convention, confocal parabolas have the same focus and the same axis of symmetry.
Love 2007, pp. 293, 297. Popenoe de Hatch and Schieber de Lavarreda 2001, p. 991. Within this extended trade route, Takalik Abaj and Kaminaljuyu appear to have been the two principal foci.
Frequently, caseous necrosis is encountered in the foci of tuberculosis infections. It can also be caused by syphilis and certain fungi. A similar appearance can be associated with histoplasmosis, cryptococcosis, and coccidioidomycosis.
In the gravitational two-body problem, the orbits of the two bodies about each other are described by two overlapping conic sections with one of the foci of one being coincident with one of the foci of the other at the center of mass (barycenter) of the two bodies. Thus, for instance, the minor planet Pluto's largest moon Charon has an elliptical orbit which has one focus at the Pluto-Charon system's barycenter, which is a point that is in space between the two bodies; and Pluto also moves in an ellipse with one of its foci at that same barycenter between the bodies. Pluto's ellipse is entirely inside Charon's ellipse, as shown in this animation of the system. By comparison, the Earth's Moon moves in an ellipse with one of its foci at the barycenter of the Moon and the Earth, this barycenter being within the Earth itself, while the Earth (more precisely, its center) moves in an ellipse with one focus at that same barycenter within the Earth.
Furthermore, photoacoustic microscopy is especially useful in the field of biomedical imaging due to its scalability. By adjusting the optical and acoustic foci, lateral resolution may be optimized for the desired imaging depth.
However, each Iranian dynasty had its own particular foci, building upon the previous dynasty's, all of which during their times were heavily influential in shaping the cultures of the world then and today.
After England graduated from the school, she taught economics as an assistant professor there. The majority of England's works were published before 1915. Her main scholarly foci were monetary economics and economic fluctuations.
CSM is an effective treatment for focal epilepsy and bilateral or multiple seizure foci. It is an effective treatment option when resective surgery to remove the affected area is not an option, generally seen with bilateral or multiple seizure foci. CSM is routinely utilized for patients with epilepsy in order to pin point the focal point of the seizures. It is used once there is a testable hypothesis regarding brain location for the epileptogenic zone, determined through a less invasive procedure, electroencephalography.
However, the term bipolar coordinates is reserved for the coordinates described here, and never used for systems associated with those other curves, such as elliptic coordinates. Geometric interpretation of the bipolar coordinates. The angle σ is formed by the two foci and the point P, whereas τ is the logarithm of the ratio of distances to the foci. The corresponding circles of constant σ and τ are shown in red and blue, respectively, and meet at right angles (magenta box); they are orthogonal.
There is often presence of Rosenthal fibers, eosinophilic granular bodies, and microcysts. Myxoid foci and oligodendroglioma-like cells may also be present, though non-specific. Long- standing lesions may show hemosiderin-laden macrophages and calcifications.
By far the predominant foci of Regulatory Science pertain to human health and well-being. This realm covers a broad range of scientific areas – including pollution and toxicology, work safety, food, drugs, and numerous others.
However, as demand for longer-lasting flats grew, the council decided that it these were necessary and that the five redevelopment areas, designated by Manzoni, were to be the key foci for modern housing provision.
The most common locations are the shaft and epyphises of long bones (fibula and humerus) but the spine, metatarsal bones, and ilium have been involved as well. Radiologic examination evidences osteolytic areas with a lobulated framework comprising radiolucent and radiodense foci admixed to speckled calcification. Cortical destruction is a common finding with no soft tissue expansion in many cases. Histopathology of the lesion shows large areas of mature fibrous stroma undergoing hyaline cartilage metaplasia resulting in conspicuous lobules or gradual transformation into chondroid foci.
The flow-line (or Winston-Welford) design method typically leads to optics which guide the light confining it between two reflective surfaces. The best known of these devices is the CPC (Compound Parabolic Concentrator). These types of optics may be obtained, for example, by applying the edge ray of nonimaging optics to the design of mirrored optics, as shown in figure "CEC" on the right. It is composed of two elliptical mirrors e1 with foci S1 and R1 and its symmetrical e2 with foci S2 and R2.
The mirror of the 2.4-meter Hiltner Telescope is aluminum-coated Cer-Vit, and usable foci include f/7.5 and f/13.5 Cassegrain foci. The telescope was built in 1986 and the mirrors were re-polished in 1991. It was named after astronomer W. Albert Hiltner (1914-1991). The Hiltner was one of the telescopes that observed the turn on a nuclear transit, along with the Swift space telescope (aka Neil Gehrels Swift Observatory since 2018) and the Gemini observatory (8 meter ground observatory).
DNA-SCARS (short for DNA segments with chromatin alterations reinforcing senescence) are nuclear substructures with persistent DNA damage and DNA damage response proteins found in senescent cells. DNA-SCARS are associated with PML nuclear bodies and the accumulation of activated ATM, ATR, CHK2 and p53 proteins. DNA-SCARS lack most of the characteristics of transient, reversible DNA damage foci, such as single-stranded DNA, active DNA synthesis, and DNA repair proteins RPA and RAD51. Telomere dysfunction-induced foci (TIF) are generally associated with DNA-SCARS.
In 2005 the landscape of the mammalian genome was described as numerous 'foci' of transcription that are separated by long stretches of intergenic space. While long ncRNAs are located and transcribed within the intergenic stretches, the majority are transcribed as complex, interlaced networks of overlapping sense and antisense transcripts that often include protein-coding genes, giving rise to a complex hierarchy of overlapping isoforms. Genomic sequences within these transcriptional foci are often shared within a number of different coding and non-coding transcripts in the sense and antisense directions For example, 3012 out of 8961 cDNAs previously annotated as truncated coding sequences within FANTOM2 were later designated as genuine ncRNA variants of protein-coding cDNAs. While the abundance and conservation of these interleaved arrangements suggest they have biological relevance, the complexity of these foci frustrates easy evaluation.
The midpoint of any segment which is an area bisector or perimeter bisector of an ellipse is the ellipse's center. The ellipse's center is also the midpoint of a segment connecting the two foci of the ellipse.
Tuija I. Pulkkinen (born 1962) is a Finnish space physicist. Her primary research foci are studying the energy flow from the solar wind to the near- Earth space environment and the energy dissipation processes in the magnetosphere.
J. W. Downs, Practical Conic Sections, Dover Publ., 2003 (orig. 1993): p. 26. Let f be the distance from the vertex V (on both the hyperbola and its axis through the two foci) to the nearer focus.
I. persulcatus ticks transmit Lyme disease, relapsing fever (Borrelia miyamotoi), babesiosis, and Siberian (TBEV-Sib) and Far Eastern (TBEV-FE) tick-borne encephalitis, and probably human granulocytic anaplasmosis as well. A recent study of the northernmost tick-borne encephalitis focus in Simo, Finnish Lapland, found I. persulcatus ticks in scattered foci along the western coast, including the Kokkola archipelago and Närpes municipality, demonstrating a northward movement of foci and an unusual combination of the TBEV-Eur strain and I. persulcatus ticks in an area with no evidence of cocirculation of tick species or TBEV subtypes.
The Consensus Model for APRN Regulation is a model and document created by the National Council of State Boards of Nursing to create consensus on licensure, accreditation, certification, and education for advanced practice registered nurses (APRNs). The model has four roles: nurse practitioner, nurse anesthetist, nurse-midwife, and clinical nurse specialist. There are six population foci: family/individual across the lifespan, adult-gerontology, pediatrics, neonatal, women’s health/gender-related, and psych/mental health. APRNs are educated and certified in one of the four roles and one or more of the population foci.
A new multi-object optical spectrograph, WEAVE, is expected to be installed during 2019. In addition the WHT is a popular telescope for single-purpose visitor instruments, which in recent years have included PAUCam, GHαFaS, PNS, INTEGRAL, PLANETPOL, SAURON, FASTCAM and ULTRACAM. Visitor instruments can use either the Cassegrain focus or one of the Nasmyth foci. A common set of calibration lamps (Helium and Neon arc lamps, and a Tungsten flat-field lamp) are permanently mounted at one of the broken- Cassegrain foci, and can be used for any of the other instruments.
The characterization of an ellipse as the locus of points so that sum of the distances to the foci is constant leads to a method of drawing one using two drawing pins, a length of string, and a pencil. In this method, pins are pushed into the paper at two points, which become the ellipse's foci. A string is tied at each end to the two pins; its length after tying is 2a. The tip of the pencil then traces an ellipse if it is moved while keeping the string taut.
To achieve the high accuracy, the following steps are carried out: Small radio opaque markers are introduced in the bone and attached to the prosthesis to serve as well-defined artificial landmarks. Two synchronised x-ray foci are used to obtain a stereo image of the bone and the prosthesis. The positions of the foci are assessed using a calibration object that holds tantalum markers at accurately known positions. The coordinates of the bone and prosthesis markers are accurately measured and the three-dimensional position of the markers is reconstructed using software.
After a 1993 PhD titled 'Primary and secondary epileptic foci from hippocampus and neocortex in the tetanus toxin model of chronic epilepsy' at the University of London, Empson moved to the University of Otago, rising to full professor.
Mining is among the first steps of producing metal and as such is one of the foci of experimental archaeometallurgy. However, experimental research on mining is mostly limited to firesetting and the reproduction and use of mining tools.
The first law was "The orbit of every planet is an ellipse with the Sun at one of the two foci." On 7 January 1610 Galileo used his telescope, with optics superior to what had been available before.
Further more: r^2_y = r^2_x - c^2. From the upper diagram one gets: S_1, S_2 are the foci of the ellipse (of the ellipsoid) in the x-z-plane and the equation r^2_z = r^2_x - a^2.
In its sixth decade, Eisenhower Fellowships developed additional programs and foci. In 2003, EF celebrated its 50th Multi Nation Program and 50th Anniversary Conference in Philadelphia called “Connecting Global Leaders.”Perrone, Marguerite. "Eisenhower Fellowship: A History 1953-2003". 2003.
It has been associated with several conditions, such as temporal and frontal lobe lesions, tumors, atrophy, tuberous sclerosis, hemangiomas, and post-infectious foci, but mainly hypothalamic hamartomas. The term "gelastic" originates from the Greek word "gelos", which means laughter.
Image quality is important in applications that require excellent robotic vision. Algorithm based on wavelet transform for fusing images of different spectra and different foci improves image quality. Robots can gather more accurate information from the resulting improved image.
Figure 2. A set of Apollonian circles. Every blue circle intersects every red circle at a right angle, and vice versa. Every red circle passes through the two foci, which correspond to points A and B in Figure 1.
In plant cells, microtubules gather at opposite poles and begin to form the spindle apparatus at locations called foci. The mitotic spindle is of great importance in the process of mitosis and will eventually segregate the sister chromatids in metaphase.
"Naranian v. Besant". [Letters to the Editor]. The Times (London). p. 7. . Until Besant's presidency, the society had as one of its foci Theravada Buddhism and the island of Sri Lanka, where Henry Olcott did the majority of his useful work.
Apollonius discovered that a circle could be defined as the set of points P that have a given ratio of distances k = to two given points (labeled A and B in Figure 1). These two points are sometimes called the foci.
Every triangle has a unique Steiner inellipse – an ellipse inside the triangle and tangent to the midpoints of the three sides of the triangle. The foci of a triangle's Steiner inellipse can be found as follows, according to Marden's theorem: Denote the triangle's vertices in the complex plane as , , and . Write the cubic equation \scriptstyle (x-a)(x-b)(x-c)=0, take its derivative, and equate the (quadratic) derivative to zero. Marden's Theorem says that the solutions of this equation are the complex numbers denoting the locations of the two foci of the Steiner inellipse.
A complicating factor is that the majority of patients have multiple independent tumor foci upon diagnosis, and these foci have independent genetic changes and molecular features. Because of this extensive inter-focal heterogeneity, it is a risk that the prognostication is set based on the wrong tumor focus. Androgen ablation therapy causes remission in 80–90% of patients undergoing therapy, resulting in a median progression- free survival of 12 to 33 months. After remission, an androgen-independent phenotype typically emerges, wherein the median overall survival is 23–37 months from the time of initiation of androgen ablation therapy.
The Hh gene is the other element that has been functionally tested in the formation of eyespots. Investigating genes involved in wing development and morphogenetic activity has led to the discovery that Hh has a primary role in the morphogenetic signaling center of the foci. In a manner that is similar to the development of Drosophila fruit flies, Hh is expressed in all cells in the posterior compartment of the developing butterfly wing during the mid fifth instar of butterfly wing development. However, in butterflies, Hh expression is significantly higher in those cells that flank the potential foci.
Lung tissue from people with IPF usually show a characteristic histopathologic UIP pattern and is therefore the pathologic counterpart of IPF. Although a pathologic diagnosis of UIP often corresponds to a clinical diagnosis of IPF, a UIP histologic pattern can be seen in other diseases as well, and fibrosis of known origin (rheumatic diseases for example). There are four key features of UIP including interstitial fibrosis in a 'patchwork pattern', interstitial scarring, honeycomb changes and fibroblast foci. Fibroblastic foci are dense collections of myofibroblasts and scar tissue and, together with honeycombing, are the main pathological findings that allow a diagnosis of UIP.
Sculpture of a Gönnersdorf venus figurine Particularly relevant research foci in the study of the behavioural development of early humans and hominids are the processes relating to subsistence patterns, mobility, settlement behaviour, and land-use patterns of Palaeolithic and Mesolithic hunter-gatherers.
Daniel Cremers is a computer scientist, Professor of Informatics and Mathematics and Chair of Computer Vision & Artificial Intelligence at the Technische Universität München. His research foci are computer vision, mathematical image, partial differential equations, convex and combinatorial optimization, machine learning and statistical inference.
Singapore's grading system in schools is differentiated by the existence of many types of institutions with different education foci and systems. The grading systems that are used at Primary, Secondary, and Junior College levels are the most fundamental to the local system used.
In an interview with Pesti Foci, Strebek said that he hopes that his team will prosper in the second half of the 2016–17 BLASZ season. Strebek's team won two consecutive matches in the 2017–18 Nemzeti Bajnokság III season with THSE Sashalom.
An example of a ribonucleoprotein-motif protein. From PDB entry 1IBM. A ribonucleoprotein particle or RNP is a complex formed between RNA and RNA- binding proteins (RBPs). The term RNP foci can also be used to denote intracellular compartments involved in processing of RNA transcripts.
42; citing Varro, Lingua Latina, 6. 16; Varro's explicit denial that the festival belongs to Venus implies his awareness of the opposite opinion. Lipka offers this apparent contradiction as an example of two Roman cults that offer "complementary functional foci" within a single festival.
In normal, non-mutant, cells FANCD2 is mono-ubiquinated in response to DNA damage. Activated FANCD2 protein co-localizes with BRCA1 (breast cancer susceptibility protein) at ionizing radiation-induced foci and in synaptonemal complexes of meiotic chromosomes (see Figure: Recombinational repair of double strand damage).
The TNG is an altazimuthal reflecting telescope with a Ritchey-Chretien optical configuration and a flat tertiary mirror feeding two opposite Nasmyth foci. It has a design derived from the New Technology Telescope (NTT), an ESO 4-meters class telescope located in La Silla (Chile). Therefore, the optical quality of the telescope is ensured by an active optics system performing real-time corrections of the optical components and compensating, in particular, for the deformations of the primary mirror, which is too thin to be completely rigid. The interface between the telescope fork and the instruments at both Nasmyth foci is provided by two rotator/adapters.
1874: Lithographie d'Ali Gouli Khan. The first Iranian physician who registered his observations about plague using modern medical science was Mohammad Razi Tabatabai, the senior physician in Naser al-Din Shah's army; his book was published under the title "Plague" in 1875. Dr. Joseph Desire Tholozan, (1820 to 1897), the royal physician of Naser Al-din Shah and the head of the ministry of health at that time, evaluated the main and natural foci of plague in Kurdistan between 1870 and 1882 and found certain foci for the disease in various villages of that area.Theodorides, J., Un grand épidémiologiste franco-mauricien: Joseph Désiré Tholoza (1820-1897).
A lemniscate of Bernoulli and its two foci F1 and F2 The lemniscate of Bernoulli is the pedal curve of a rectangular hyperbola In geometry, the lemniscate of Bernoulli is a plane curve defined from two given points F1 and F2, known as foci, at distance 2c from each other as the locus of points P so that PF1·PF2 = c2. The curve has a shape similar to the numeral 8 and to the ∞ symbol. Its name is from lemniscatus, which is Latin for "decorated with hanging ribbons". It is a special case of the Cassini oval and is a rational algebraic curve of degree 4.
This lemniscate was first described in 1694 by Jakob Bernoulli as a modification of an ellipse, which is the locus of points for which the sum of the distances to each of two fixed focal points is a constant. A Cassini oval, by contrast, is the locus of points for which the product of these distances is constant. In the case where the curve passes through the point midway between the foci, the oval is a lemniscate of Bernoulli. This curve can be obtained as the inverse transform of a hyperbola, with the inversion circle centered at the center of the hyperbola (bisector of its two foci).
Necrotic foci on liver In acute cases, a green diarrhea can be an early symptom. The most typical symptom, in chronic cases, is the swelling of the wattles. It is more frequent in resistant local breeds. Rather than a general infection, localized infections are more characteristic.
Nash et al. (1995) studied the spread of this species in Great Britain. Besides the "natural" spread of the insect, they found several foci of colonization outside the main distribution range that were undoubtedly due to human activities. Damage The wingspan is 6 to 8 mm.
Peritoneal and thoracic cavities contains a great quantity of fluids, as does the pericardial sac. The liver is sometimes swollen with perihepatitis. There appear a great number of necrotic foci, 3 to 4 mm diameter, which extend deeply in the organ. Hepatic lymph nodes are enlarged.
Ives/1920 German optics was overwhelmingly superior, as exemplified by Carl Zeiss lenses and optical glass. The Allies had to quickly learn to make lenses especially for long foci. In the meantime they had to make do with such short-focus lenses as could be found.
Anhalt is one of the earliest serious composers of electronic music. His music underwent changes over the years, and can be divided into four periods.Applebaum, p.3 Anhalt has a librettist for his dramatic works, beginning in 1969 with Foci, and ending in 1999 with Millennial Mall.
It is a very common finding in bladder biopsies and cystectomies, and most often found in the trigone area. Cystitis glandularis lesions are usually present as small microscopic foci; however, occasionally it can form raised intramucosal or polypoid lesions. The cystitis glandularis lesions are within the submucosa.
On CT scan, it may show rosary sign, showing mucosal epithelium with intramural diverticula. Magnetic resonance imaging also plays an important role in the diagnosis of Rokitansky–Aschoff sinuses. In fat-suppression MRI, RAS present with small, rounded, high signal intensity foci, called “pearl necklace sign”.
On 1 August 2010, the area of the forest fires was . The Central Regional Center MOE Russia website reported that in Moscow Oblast 130 foci of natural fires were detected, covering the area of 880 hectares. Of those, 67 fires covered an area of 178 hectares.
Cultivation is best in hardiness zones 5-9 and trees take 7-8 years from seedling to fruiting. KYSU has created the three cultivars KSU-'Atwood', KSU-'Benson', and KSU-'Chappell', with foci on better flavors, higher yields, vigorous plants, and low seed-to-pulp ratios.
Logo The International Polar Years (IPY)Barr, Susan and Lüdecke, Cornelia (Eds.), 2010, The History of the International Polar Years (IPYs). Series: From Pole to Pole, Vol. 1, Springer-Verlag, Berlin, Heidelberg, XI, 319 pp. , are collaborative, international efforts with intensive research foci on the polar regions.
Beyond population foci, APRNs can focus on and become certified in a specialty. The model establishes education standards for programs that prepare APRNs as well accreditation of certification boards. Individual state boards of nursing have either adopted or in the process of adopting the model for APRN regulation.
Fish demonstrated signs of lethargy and disoriented swimming. There were ulcerative lesions, multiple dark foci in the gills, and non-ulcerative dermal masses found. In critical cases, some fish showed a variety of inflammatory responses including the formation of microabscesses. Lesions in the brain and kidneys were also found.
The protozoa are transmitted by the bite of the insect vector. The sporozoites migrate to the liver where they typically form merocysts within the liver parenchyma. These may also develop in the spleen and lungs. Macroscopically these may appear as white to gray nodular foci within the tissue.
The degree is awarded by the University of the West Indies. Minors in Theology. It is also possible to take a minor in theology in one of three foci: Biblical Studies, Historical & Pastoral Studies, or Systematic & Religious. The degree is awarded by the University of the West Indies.
The function of macroH2A has generally been assumed to be transcriptional silencing; most recently, it has been suggested that macroH2A is important in repressing transcription at Senescence-Associated Heterochromatin Foci (SAHF). Chromatin that contains macroH2A is impervious to ATP-dependent remodeling proteins and to the binding of transcription factors.
Blocking the toxic gain of RNA foci to prevent RNA sequestration might be helpful as well as making up for the lack of C9ORF72. Either of these targets as well as a combination of them might be promising future targets in minimizing the effects of the C9ORF72 repeat expansion.
Baird, A.D., Wilson, S.J., Bladin, P.F., Saling, M.M., & Reutens, D.C. (2002). Hypersexuality after temporal lobe resection. Epilepsy & Behavior, 3(2), 173-181. Due to limited cases studying the connection between witzelsucht and hypersexuality, studies concerning epileptic foci on the temporal lobe could be looked at to gain more information.
It later became more practical after they were equipped with professional cars. Although Kurdistan had a history of plague, it was due to the plague outbreak in Kurdistan in the same year that for the first time the research teams were dispatched to an area in which they could control the outbreak via quarantining the foci and epidemiological procedures on the humans and rodents. Studies of the plague foci in this region and the importance of this disease motivated Dr. Baltazard, Dr. Shamsa, Dr. Karimi, Dr. Habibi, Dr. Bahmanyar, Dr. Agha Eftekhari, Dr. Farhang Azad, Dr. Seyyedian and Dr. Majd Teymouri to conduct extensive scientific and epidemiologic studies after educating expert technicians and providing sufficient facilities.Rezvan H, et al.
More generally, for any collection of points Pi, weights wi, and constant C, one can define a circle as the locus of points X such that :\sum w_i \, d^2(X,P_i) = C. The director circle of an ellipse is a special case of this more general construction with two points P1 and P2 at the foci of the ellipse, weights w1 = w2 = 1, and C equal to the square of the major axis of the ellipse. The Apollonius circle, the locus of points X such that the ratio of distances of X to two foci P1 and P2 is a fixed constant r, is another special case, with w1 = 1, w2 = −r2, and C = 0\.
The obelisk marked a centre, and a granite fountain by MadernoIt was set up in 1613 by order of Paul V stood to one side: Bernini made the fountain appear to be one of the foci of the ovato tondoThe actual foci are marked in the paving by roundels of stone six or seven metres beyond the outer ring of the compass rose centered on the obelisk, on either side. When the visitor stands on one, the ranks of columns line up perfectly behind one another. (Touring Club Italiano, Roma e Dintorni). embraced by his colonnades and eventually matched it on the other side, in 1675, just five years before his death.
The Hawaiian Harbors department has now filed for a "disposal" notice to the state department of historic artefacts. As the ship has been in Hawaii for over 50 years, it is now considered to be of cultural and historic importance, and the department has advised FOCI that the easiest way to take control of the Falls of Clyde is to bid as part of the "disposal" process. FOCI intends to bid, and has advised DOT harbours accordingly. Their proposal is to remove the FOC and repurpose her in a way that protects her heritage, but also offers a future that will support the marine environment and serve future generations of communities around the world.
On the process of new dialect formation', in: Raymond Hickey (ed.) Motives for Language Change. Cambridge: University Press, 2003, pp. 213-239. Among his recent research foci have been life-span‘Twentieth-century Received Pronunciation: Stop articulation’, in: Raymond Hickey (ed.) Listening to the Past. Audio Records of Accents of English.
Sharer and Traxler 2006, p.321. During the Early Classic period (c. 250–600) the Mundo Perdido became one of the twin foci of the city, the other being the North Acropolis.Martin and Grube 2000, p.29. From AD 250 to 378 it may have served as the royal necropolis.
In subsequent years both organizations have flourished, with somewhat separate restoration foci. The Guthries continued to run Save Venice successfully until their joint retirements in 2006. The biennial galas still take place in Venice, linked to important Venetian festivals such as Carnevale, Regatta Storica, Feast of the Redentore, or the Biennale.
Rasmus Carl Stæger 1861 by Rudolph Striegler Rasmus Carl Staeger (1800–1875) was a Danish entomologist. Staeger was born and died in Copenhagen, over the course of his life serving as a judge, financial advisor to the Danish government, and entomologist, focusing on Diptera. His foci were Dolichopodidae, Sepsidae and Chironomidae.
Mitochondrial DNA is the small circular chromosome found inside mitochondria. These organelles found in cells have often been called the powerhouse of the cell. The mitochondria, and thus mitochondrial DNA, are passed almost exclusively from mother to offspring through the egg cell. Electron microscopy reveals mitochondrial DNA in discrete foci.
Confocal ellipsoids share the same foci, which are given for the example above by : f_1^2=a^2-b^2=(a^2+\lambda)-(b^2+\lambda), \, : f_2^2=a^2-c^2=(a^2+\lambda)-(c^2+\lambda), \, : f_3^2=b^2-c^2=(b^2+\lambda)-(c^2+\lambda).
Steifel, p. 7-8. Stiefel wrote that it was by then "nonexistent" in the City of Detroit. Suburban municipalities defined by Stiefel as foci included Bloomfield Hills, Farmington Hills, Oak Park, Royal Oak, Southfield, and West Bloomfield. Smaller congregations of Jewish people existed in other municipalities such as Livonia and Trenton.
In this case, it is said that often, e.g. in breast and prostate cancer, the tissue structure in distant metastatic foci is similar to the primary tumor structure. According to Friedl and Gilmour, several assumptions can be made based on these data. First, invasion and metastasis can occur without EMT.
Since the formal management ordinance of August 2010, the Preserve's has been sub-divided into three management zones. A core zone comprising is strictly protected; a buffer zone where limited use is permitted with educational and experimental foci comprises ; and a third area open for public use comprises an additional .
Novosibirsk, Nauka, 1985 .- 96 p. in 1985 published the world's first monograph devoted to PVL. Vlasyuk (1981) first revealed the high incidence of optic radiation lesions and demonstrated that PVL - a persistent process that the old necrosis can join a new, foci of PVL may be at different stages of development.
Depth of earthquake foci in cross section, modified from Obana, et al., 2002 The Nankai Trough is the near-surface extension of a zone of active seismicity that dips beneath SW Japan. The rupture zone has been subdivided into five areas with respect to seismic modelling (Mitsui et al., 2004).
A alt= Choriocarcinomas are exceptionally rare which account for 2.1%-3.4% of all OGCTs. Under gross examination, the syncytiotrophoblast cells are aligned in a plexiform arrangement with the mononucleated cytotrophoblast cells surrounding the foci of the hemorrhage. Choriocarcinomas can be divided into gestational choriocarcinomas and non-gestational choriocarcinomas which have immunohistochemical differences.
MTOCs can be freely dispersed throughout the cytoplasm or centrally localized as foci. The most notable MTOCs are the centrosome at interphase and the mitotic spindle poles. Centrioles can act as markers for MTOCs in the cell. If they are freely distributed in the cytoplasm, centrioles can gather during differentiation to become MTOCs.
This perception is subject to what foci the observer has selected, along with the information provided before or after the observation. Second, the linking is initiated by a statement response, "painting a picture" to make sense of what was observed. This retrieval process results in either an accurate memory or a false memory.
Its strength and specificity can detect the small foci of neuroblastic tumors metastatic to the bone marrow, an identification critical for determining disease staging. PHOX2B staining also overcomes frequent obstacles to neuroblastoma detection in post-treatment samples, which frequently exhibit dense fibrosis, prominent inflammatory infiltrates, and/or diffuse calcification.Hata et al. (2015).
43 of the 74 foci in the U.S. were traced to contact with Amazon parrots. Links were traced to Japan, Caribbean, Germany, Central America and South America. Between November 1929 and May 1930, the U.S. recorded 169 cases, of which 33 died. New York was the centre of the East Coast bird trade.
Thus one can speak of the construction of Antarctica as a continent by and for science. In connection with the Fourth International Polar Year (2007–2009) worked on the history of the four international polar years to highlight changing foci, conditions of research, logistics and epistemological characteristics over the past 125 years.
They are pathognomic foci of fibrinoid necrosis found in many sites, most often the myocardium. Initially they are surrounded by lymphocytes, macrophages, and a few plasma cells, but they are slowly replaced by a fibrous scar. Aschoff bodies are found in all the three layers of the heart, least chance in the pericardium.
In this pattern, hepatocellular necrosis is associated with infiltration of inflammatory cells. There can be three types of drug-induced hepatitis. (A) viral hepatitis is the most common, where histological features are similar to acute viral hepatitis. (B) in focal or non-specific hepatitis, scattered foci of cell necrosis may accompany lymphocytic infiltration.
The most famous spiric section is the Cassini oval, which is the locus of points having a constant product of distances to two foci. For comparison, an ellipse has a constant sumfocal distances, a hyperbola has a constant difference of focal distances and a circle has a constant ratio of focal distances.
The municipality is formed by the city of Colle di Val d'Elsa and the towns and villages (frazioni) of Bibbiano, Borgatello, Campiglia dei Foci, Castel San Gimignano, Collalto, Gracciano dell'Elsa, Le Grazie, Mensanello and Quartaia. Other notable villages within the comune include Boscona, Buliciano, Coneo, Lano, Montegabbro, Onci, Partena, Paurano, Sant'Andrea and Scarna.
The neighbourhood more resembles an ellipse, with this location and city hall the foci. Existing bus destinations became Brighouse Station. The Richmond-Brighouse Station bus loop, originally scheduled to open in 2019, should be completed in 2020. Although outside the original Sam Brighouse landholding, some regard Lansdowne Centre as part of Brighouse.
With La Peau de chagrin, on the other hand, the talisman represents Valentin's soul; at the same time, his demise is symbolic of a greater social decline.Dedinsky, p. 36. Balzac's real foci in the 1831 novel are the power of human desire and the nature of society after the July Revolution.Hunt, p.
Lipka, Michael, Roman Gods: A Conceptual Approach, Brill, 2009, p. 42; citing Varro, Lingua Latina, 6. 16; Varro's explicit denial that the festival belongs to Venus implies his awareness of opposite scholarly and commonplace opinion. Lipka offers this apparent contradiction as an example of two Roman cults that offer "complementary functional foci".
It oscillated no more than 1 to 2 degrees over much of the region. With the cooperation of many of his squadron teammates in obtaining many hundreds of statistical readings, startling results were revealed: The center of the north magnetic dip pole was on Prince of Wales Island some NNW of the positions determined by Amundsen and Ross, and the dip pole occupied a larger elliptical area, with foci about apart on Boothia Peninsula and Bathurst Island. Klein called the two foci local poles, for their importance to navigation in emergencies when using a "homing" procedure. About three months after Klein's findings were officially reported, a Canadian ground expedition was sent into the Archipelago to locate the position of the magnetic pole.
A more general version of the theorem, due to , applies to polynomials whose degree may be higher than three, but that have only three roots , , and . For such polynomials, the roots of the derivative may be found at the multiple roots of the given polynomial (the roots whose exponent is greater than one) and at the foci of an ellipse whose points of tangency to the triangle divide its sides in the ratios , , and . Another generalization () is to n-gons: some n-gons have an interior ellipse that is tangent to each side at the side's midpoint. Marden's theorem still applies: the foci of this midpoint-tangent inellipse are zeroes of the derivative of the polynomial whose zeroes are the vertices of the n-gon.
265 with her sacred hearth being named Iliaci foci (Trojan hearth).The Classical Journal, Volume 15 p.214 The priestesses of Vesta, known as Vestal Virgins, administered her temple and watched the eternal fire. Their existence in Alba Longa is connected with the early Roman traditions, for Silvia the mother of Romulus was a priestess.
Orrego Corzo and Schieber de Lavarreda 2001, p. 788. The early Maya style of monument at Takalik Abaj is closely linked to the style of monument at Kaminaljuyu, showing mutual influence. This interlinked style spread to other sites that formed part of the extended trade network of which these two cities were the twin foci.
Lipka, Michael, Roman Gods: A Conceptual Approach, BRILL, 2009, p. 42; citing Varro, Lingua Latina, 6. 16; Varro's explicit denial that the festival belongs to Venus implies his awareness of the opposite opinion. Lipka offers this apparent contradiction as an example of two Roman cults that offer "complementary functional foci" within a single festival.
Mt. Hamilton Telescopes: Carnegie Double Astrograph It was then transported to Mount Hamilton, where the blank was ground and polished by the observatory. The telescope is noted for having three foci, prime focus, Cassegrain focus, and coudé focus. After several decades of celebrated use, it was also fitted with an early adaptive optics system.
The skin is edematous, hyperemic, with small focal hemorrhages, which are covered with dry crusts. Subsequently, on the fingers, ears and tail, foci of necrosis are formed, covered with dark brown crusts, which then disappear. Sometimes amputation of limbs or phalanges of the fingers and tail occurs, thus the name ectromelia given to this virus.
In March 1886, she stopped at Hong Kong and Canton. On 19 April, the warship returned to Japan at Yokohama. That port and Hakodate served as the foci of her operations until the first week in August. Alert put to sea from the latter on 5 August, beginning a voyage back to the United States.
In pre-historic times Galicia was one of the primary foci of Atlantic European Megalithic Culture.Benozzo, F. (2018): "Uma paisagem atlântica pré-histórica. Etnogénese e etno-filologia paleo-mesolítica das tradições galega e portuguesa", in proceedings of Jornadas das Letras Galego- Portugesas 2015-2017. Università de Bologna, DTS and Academia Galega da Língua Portuguesa. pp.
Mff is an outer mitochondrial membrane protein that binds to the GTPase Drp1; the Mff-Drp1 complex is what promotes mitochondrial fission. Knockdown of Mff causes the mitochondrial network to expand (by releasing the Drp1 foci from the outer mitochondrial membrane), while Mff overexpression causes it to become fragmented (by stimulating mitochondrial recruitment of Drp1).
At Breitenbach there is evidence for spatially differentiated activity zones, with foci of specific activities. This is suggested by the presence of large stone manuports, imported and intentionally arranged sandstone slabs, pits and hearths. The sandstone slabs in particular hint at repeated longer-term occupations. Four high-lithic concentrations were tentatively labelled as “lithic workshops”.
JCT is morphologically characterized by multiple foci malignant mesenchymal epithelioid cells with, often with admixed necrosis, and a perivascular growth pattern. The immunophenotype is rather characteristic, as the neoplastic cells express renin, CD34, smooth muscle actin, CD138, vimentin, collagen IV and is negative for cytokeratins as well as for S100, c-Kit and desmin.
CASA de Maryland (CASA) (English: CASA of Maryland) is a Latino and immigration advocacy-and-assistance organization based in Maryland. It is active throughout the state, but has major foci in Prince George's County, Montgomery County and Baltimore. CASA influences Maryland politics on a wide range of policies, ranging from law-enforcement to education.
Examples include the hippopede and the Cassini oval and their relatives, such as the lemniscate of Bernoulli. The Cassini oval has the remarkable property that the product of distances to two foci are constant. For comparison, the sum is constant in ellipses, the difference is constant in hyperbolae and the ratio is constant in circles.
Even Price was cited as an authoritative source espousing conservative intervention at focal infections.Journal of the Canadian Dental Association, 1935;1:451. Kells, too, advocated conservative dentistry. Many dentists were "100 percenters", extracting every tooth exhibiting either necrotic pulp or endodontic treatment, and extracted apparently healthy teeth, too, as suspected foci, leaving many persons toothless.
AllMusic critic Ned Raggett wrote that Remnants of a Deeper Purity "succeeds like no other Black Tape release before it, the logical extension of Rosenthal's musical and lyrical foci into a lengthy, commanding, and beautiful experience." He ranked it at number 93 on his list of the best albums of the 1990s for Freaky Trigger.
SII contains two more sensory homunculi. Information from one side of the body is generally represented on the opposite side in SI, but on both sides in SII. Functional MRI imaging of a defined stimulus (for example, stroking the skin with a toothbrush) "lights up" a single focus in SI and two foci in SII.
123I-labelled iomazenil can be used to image epileptic seizure foci as an alternative to 18F-fludeoxyglucose PET imaging. The effect of iomazenil of reducing levels of GABA in the brain was used by researchers to exacerbate symptoms in patients with schizophrenia in a laboratory study, supporting the theory that a GABA deficiency underlies that disease.
On July 2, 2011, the telescope operator in Hilo noted an anomaly from the top unit of the telescope. Upon further examination, coolant from the top unit was found to have leaked over the primary mirror and other parts of the telescope. Observation using Nasmyth foci resumed on July 22, and Cassegrain focus resumed on August 26.
Div.) Concentrations in: Chaplaincy Pastoral Counseling Pastoral Ministry General Pastoral Studies Doctor of Ministry (D.Min.) With Foci in: Preaching, Leadership, Marketplace Ministry, or Urban Ministry. Charlotte Christian College and Theological Seminary operates on a semester system. The institution focuses on practical training for inner-city ministers; most courses are held in the evening to accommodate working adults.
As of 2011 five cases had been reported, involving rib, tibial epiphysis, ulna, distal tibia and femur. Young individuals are prevalently affected but one case involved a 50-year-old woman. Pain, swelling of possibly long duration, fever and increased ESR are some of the main clinical findings. X-ray examination shows lytic foci with sclerotic margins.
The mature merocysts are visible to the naked eye on the hepatic surface. These appear as raised, grayish-white to translucent foci with a central accumulation of fluid. Multiple, depressed areas of fibrosis with calcification representing healed lesions may also be found. Microscopically the liver cysts have an irregular central space filled with faintly eosinophilic, acellular, flocculent material.
Corvino is Professor and Chair of Philosophy at Wayne State University in Detroit, Michigan.Profile at Wayne State University He began teaching there in 1998 and received tenure in 2007. His foci are ethics, applied ethics, and early modern philosophy. Other areas in which he has concentrated include the philosophy of religion, social philosophy, and political philosophy.
Alongside those household gods was Vesta, who has been referred to as Vesta Iliaca (Vesta of Troy),Ovid Fasti vi. 265 with her sacred hearth being named Ilaci foci (Trojan hearth). Worship of Vesta, like the worship of many gods, originated in the home, but became an established cult during the reign of either Romulus, vol. 1, note no.
Breeding then begins anew, occurring in dense, harem-structured population foci within a narrow band of preferred habitat, from April through October. Young females often continue to live near their birthplace, while young males often disperse, due to the presence of other dominant males. The young males remain near their original colony, probably in suboptimal habitat.
The Chinese Future Giant Telescope has a primary focal ratio of 1.2. Its primary mirror is segmented with 1020 annular submirrors arranged in 17 concentric annuli. Each segment has average length and width both of 0.8 m. Apart from a conventional Cassegrain focus, four Nasmyth foci on two double-deck platforms on both sides are also present.
Discrete foci of pyknotic and karyorhectic nuclei and inflammation are seen within the cuticular tissues. The lymphoid organ might display spheroids, but is otherwise unremarkable. The genome of the virus has been cloned and cDNA probes are available for diagnosis. Reverse transcriptase polymerase chain reaction (RT-PCR) methods have been developed for detection of TSV and are very sensitive.
In March 2017 Anke Grotlüschen organised a conference in honour of Peter Faulstich together with Silke Schreiber-Barsch, Christine Zeuner and Sabine Schmidt-Lauff as well as Hannelore Faulstich-Wieland about the political aspects in Adult Education, one of the main foci of the work of Peter Faulstich. Anke Grotlüschen is married and lives in Hamburg.
Ultrasound is the recommended diagnostic modality used to diagnose cervical ectopic thymus. The thymus has a unique appearance on ultrasound which allows for specific diagnosis. Upon ultrasound, ectopic thymus appears hypoechoic with characteristic linear echogenic foci. However, MRI can and has been utilized as well to better characterize and identify the location of the ectopic thymus.
The Geballe Laboratory for Advanced Materials (G-LAM) at Stanford University supports research on advanced materials. Major research foci include information storage materials. G-LAM is an Independent Laboratory that was established on September 1, 1999. Its mission is to support collaborative research programs on advanced materials and foster interdisciplinary research and education for undergraduate, graduate, and postdoctoral students.
Oncogenic properties of PLK1 are believed to be due to its role in driving cell cycle progression. Supporting evidence comes from the overexpression studies of PLK1 in NIH3T3 cell line. These cells become capable of forming foci and growing in soft agar and more importantly, these cells can form tumors in nude mice due to PLK1 overexpression.
In August 2019, Veress was loaned out from Sepsi Sfântu Gheorghe to Hungarian club Mosonmagyaróvári TE for the 2019-20 season.NB III foci - A Sepsitől igazolt támadót a Credobus Mosonmagyaróvár, kisalfold.hu, 28 August 2019 However, the club's manager announced in January 2020, that Veress had left the club.Az ősz értékelése, tervek és célok tavaszra – Varga Lászlóval beszélgettünk, mte1904.
As discussed above, every triangle has a unique inscribed circle (incircle) that is interior to the triangle and tangent to all three sides. Every triangle has a unique Steiner inellipse which is interior to the triangle and tangent at the midpoints of the sides. Marden's theorem shows how to find the foci of this ellipse.Kalman, Dan.
Chondrocalcinosis can be visualized on projectional radiography, CT scan, MRI, US, and nuclear medicine. CT scans and MRIs show calcific masses (usually within the ligamentum flavum or joint capsule), however radiography is more successful. At ultrasound, chondrocalcinosis may be depicted as echogenic foci with no acoustic shadow within the hyaline cartilage.Arend CF. Ultrasound of the Shoulder.
While at the National Museum of Korea, she propagated cultural diversity in collection, exhibition, and education programs, creating Department of Asian Art and Department of Education and improving Asian art collection and galleries. Another of her foci was to increase the number of foreign visitors, which dropped radically with the museum's move to its new facilities.
Previous human studies have shown an association between temporal lobe dysfunction and altered sexual behavior. There has also been evidence of hypersexual behavior after epileptic seizures. Epileptic foci can be found on the temporal lobe, near the amygdala. It has been postulated that there is an increased likelihood that a patient would exhibit hypersexuality directly after a seizure.
In case of c=0 the ellipse is a circle and the cyclide a torus of revolution with d the radius of the generating circle (generatrix). In the diagram: \; a=1,\; b=0.99,\ d=0.25\; . Maxwell: Property of the foci of the directrix ellipse. The ellipse is the equidistant set of the blue and purple circles.
Environmental factors seem to promote deposition of iron in the vulnerable brain foci, and Aaseth has studied and discussed the role of iron chelation in the disease- modifying treatment of Parkinson's disease.Dusek, P., Schneider, S. A., & Aaseth, J. (2016). Iron chelation in the treatment of neurodegenerative diseases. Journal of Trace Elements in Medicine and Biology, 38, 81-92.
The figures to which they apply require also an areal center (Greek kentron), today called a centroid, serving as a center of symmetry in two directions. These figures are the circle, ellipse, and two-branched hyperbola. There is only one centroid, which must not be confused with the foci. A diameter is a chord passing through the centroid, which always bisects it.
The idea for the name and logo comes from the astronomical term Apoapsis: An apsis (Greek apsis) is the point of greatest or least distance of a body from one of the foci of its elliptical orbit. The point of farthest excursion is called the Apoapsis (Greek apó, “from”). It’s actually the point in an orbit farthest from the body being orbited.
The Well (Quantum Corral) (2009) by Julian Voss-Andreae. Created using the 1993 experimental data by Lutz et al., the gilded sculpture was pictured in a 2009 review of the art exhibition "Quantum Objects" in the journal Nature. The mirage occurs at the foci of a quantum corral, a ring of atoms arranged in an arbitrary shape on a substrate.
Cozzutto C(1981). Uterus-like mass replacing ovary: Report of a new entity. Arch Pathol Lab Med 105: 508-514. Different pathogenetic views have been suggested for this anomaly: a) a metaplastic change in endometriosis foci bringing about smooth muscle hyperplasia; b) a congenital anomaly due to fusion defects of the Muellerian ducts; and c) a sub-coelomic transformation of the mesenchyme.
David Starr Newbury (born 1942) is the Gwendolen Carter professor of African studies at Smith College, Massachusetts. He received his PhD from the University of Wisconsin–Madison in 1979 for thesis titled Kings and clans on Ijwi Island (Zaire), c. 1780-1840 under the supervision of Jan Vansina. His academic work has three major foci within East and Central Africa.
MRI of a child experiencing seizures. There are small foci of grey matter heterotopia in the corpus callosum, deep to the dysplastic cortex. (double arrows) Gray matter heterotopias are neurological disorders caused by clumps of gray matter (nodules of neurons) located in the wrong part of the brain. A grey matter heterotopia is characterized as a type of focal cortical dysplasia.
Filion et al., 1988Tremblay et al. 1989 Focusing is not a property of the striatopallidal system. But, the very particular and contrasted geometry of the connection between striatal axons and pallidonigral dendrites offers particular conditions (the possibility for a very large number of combinations through local additions of simultaneous inputs to one tree or to several distant foci for instance).
Students complete four units of study per year and are grouped according to their age. Major foci for the next three years include the development of whole school approaches to Gifted Education, ICT, Literacy and Outcomes planning. Students may also elect to participate in the school sport and music programs. Annandale participates in many sports including Soccer, Netball, Rugby League and Hockey.
The ventricular beats typically have a right axis deviation. Multiple morphologies of ventricular tachycardia may be present in the same individual, suggesting multiple arrhythmogenic foci or pathways. Right ventricular outflow tract (RVOT) tachycardia is the most common VT seen in individuals with ACM. In this case, the EKG shows a left bundle branch block (LBBB) morphology with an inferior axis.
Catheter ablation may be used to treat intractable ventricular tachycardia. It has a 60–90% success rate. Unfortunately, due to the progressive nature of the disease, recurrence is common (60% recurrence rate), with the creation of new arrhythmogenic foci. Indications for catheter ablation include drug-refractory VT and frequent recurrence of VT after ICD placement, causing frequent discharges of the ICD.
All the departments of AITM have their student forums and conduct several events to provide students with the finest opportunities to showcase their skills. The departmental student forums are Technovate (Department of Electronics and Communication Engineering), Mecsico (Department of Mechanical Engineering), Synergy (Department of Electrical and Electronics Engineering), Continua (Department of Civil Engineering) and Foci (Department of Computer Science and Engineering).
All potential foci of infection should be intercepted; these include periodontal and endodontic lesions, residual roots, partially erupted and malpositioned third molars, peri-implantitis, and mucosal lesions. When periodontitis is suspected, a periodontal chart should be recorded. Orthodontic appliances can be maintained if they do not interfere with oral hygiene. Uremia is commonly seen in patients who undergo dialysis due to renal insufficiency.
His television writing credits include Star Trek: Voyager, JAG, Xena: Warrior Princess, The Pretender, and The Outer Limits. He also created the comedy/action series Jack of All Trades. Morris' primary research foci are transportation, land use and well-being; transportation history; and transportation and disadvantaged populations. In addition to teaching and research at Clemson, Morris writes about transportation for the "Freakonomics" blog.
Therefore, IRS-1 acts as major regulator of PI3K in lung adenocarcinoma. Some evidence shows role of IRS-1 in hepatocellular carcinoma (HCC). In rat model, IRS-1 focal overexpression is associated with early events of hepatocarcinogenesis. During progression of preneoplastic foci into hepatocellular carcinomas expression of IRS-1 gradually decreases, which is characterises a metabolic shift heading towards malignant neoplastic phenotype.
Demodecosis in cattle caused by Demodex bovis can occur as dense, localized infestations with inflammation of the epidermis in hair follicles. This leads to pustular folliculitis and indurated (thickened) plaques within the skin. On cattle, these localized foci of infestation can become so large as to be clearly visible externally. The value of the hides from cattle infested this way is reduced.
Familial hypertriglyceridemia can follow an autosomal dominant monogenic inheritance pattern. The frequency of heterozygous carriers of certain pathologic mutations in the LPL gene can range from 0.06% to 20%. It is important to note that dissimilar mutations can confer varying degrees of underlying pathology. However, most cases of familial hypertriglyceridemia follow a polygenic inheritance pattern involving mutations in multiple genetic foci.
Harbors were important foci of early European American settlement of California; and cities have developed adjacent to the larger ones.Donley, Allan, Caro and Patton Atlas of California (1979) Pacific Book Center pp.12&13 Unique aquatic ecosystems of limited geographical extentReid, George K. Ecology of Inland Waters and Estuaries (1961) Van Nostrand pp.69-80 have been impacted by waste disposal practices.
MR appearance depends on composition of the intra-articular body. Entirely cartilaginous bodies will appear isointense to muscle on T1 and hyperintense to muscle on T2 weighted images. Partly calcified intra-articular bodies demonstrate foci of absent signal on all pulse sequences. Like CT arthrography, MR with gadolinium may be used to detect intra-articular bodies that have not yet calcified.
Symptoms in these male rats included: bloody eyes, ataxia, cramps, diuresis, weight loss. Another study found an LD50 of 770 mg/kg (male) and 702 mg/kg (female) after administering these rats with benzoyl chloride in corn oil. Besides the same symptoms described earlier, upon necropsy lung congestion, thymus with red foci and yellow stained urogenital region and fluid filled intestines were found.
Alticola argentatus is effected by the plague, a bacterial infection caused by Yersinia pestis. It is enzootic in wild rodent populations over large rural areas of Mongolia, and has the most active natural plague foci in the westernmost regions. The marmot flea Oropsylla silantiewi is considered the primary vector for the plague. Human cases of plague have been recorded in Mongolia since 1897.
Around the strands calcium and phosphate precipitate on the surface of these strands, within days to weeks becoming crystals of hydroxyapatite. In order to mineralise the bone, the osteoblasts secrete vesicles containing alkaline phosphatase. This cleaves the phosphate groups and acts as the foci for calcium and phosphate deposition. The vesicles then rupture and act as a centre for crystals to grow on.
In 1985, Dr. Goodman founded and served as Chief of the OCD Clinic at Yale University. During this time, along with his colleagues Lawrence Price and Steven Rasmussen, he developed the Y-BOCS, which is widely used in research and clinical practice to determine the severity of OCD and to monitor improvement during treatment. It has since been translated into numerous languages. Goodman and his colleagues have also developed the Yale-Brown Obsessive-Compulsive Scale—Second Edition (Y-BOCS-II) in an effort to modify the original scale. Other rating scales developed by Goodman and his colleagues include: the Children’s Yale-Brown Obsessive Compulsive Scale (CY- BOCS), Florida Obsessive Compulsive Inventory (FOCI), the Children's Florida Obsessive Compulsive Inventory (C-FOCI), Level 2—Repetitive Thoughts and Behaviors (Cross-cutting symptom measure used in the DSM-5),American Psychiatric Association.(2013).
ASEN has multiple campaign foci including climate change, coal mining, green jobs, campus sustainability (energy/emissions & recycled paper), nuclear power, Gold and Uranium mining and the genocide of Indigenous peoples. In addition, the network builds and lives-out alternative ideas and lifestyles through community projects such as co-operatives (food, housing and transport), on-campus permaculture gardens and by investing in community supported agriculture.
There are several dozen ideas contemplated in the book altogether. They gravitate toward two main foci: First, all types of intellectual property treat cultural, or spiritual, for that matter, phenomena as material things, which, according to the author, is nonsense in principle. Second, the analysis of how IP works shows that it actually does exactly the opposite to what it supposed to do. It suppresses creativity.
The predominant subtype is prognostic for survival after complete resection. To reveal the adenocarcinomatous lineage of the solid variant, demonstration of intracellular mucin production may be performed. Foci of squamous metaplasia and dysplasia may be present in the epithelium proximal to adenocarcinomas, but these are not the precursor lesions for this tumor. Rather, the precursor of peripheral adenocarcinomas has been termed atypical adenomatous hyperplasia (AAH).
The ACLS guidelines were updated by the American Heart Association and the International Liaison Committee on Resuscitation in 2010. New ACLS guidelines focus on BLS as the core component of ACLS. Foci also include end tidal monitoring as a measure of CPR effectiveness, and as a measure of ROSC. Other changes include the exclusion of atropine administration for pulseless electrical activity (PEA) and asystole.
Plague has endemically resided in Madagascar since it was first brought to the island from India in 1898, on the central high plateau of Madagascar, usually occurring every year as a seasonal upsurge during the rainy season.Andrianaivoarimanana, V., Kreppel, K., Elissa, N., Duplantier, J. M., Carniel, E., Rajerison, M., & Jambou, R. (2013). Understanding the persistence of plague foci in Madagascar. PLoS Neglected Tropical Diseases, 7(11), e2382.
This has motivated researchers to develop senolytic drugs to kill and eliminate senescent cells to improve health in the elderly. The nucleus of senescent cells is characterized by senescence-associated heterochromatin foci (SAHF) and DNA segments with chromatin alterations reinforcing senescence (DNA-SCARS). Senescent cells affect tumor suppression, wound healing and possibly embryonic/placental development, and play a pathological role in age-related diseases.
There are an infinite number of refractive-index profiles that can produce this effect. The simplest such solution was proposed by Rudolf Luneburg in 1944. Luneburg's solution for the refractive index creates two conjugate foci outside of the lens. The solution takes a simple and explicit form if one focal point lies at infinity, and the other on the opposite surface of the lens.
Echinostomiasis is endemic in South East Asia and the Far East, in countries including China, Korea, Taiwan, Philippines, Malaysia, Indonesia and India. Echinostomiasis has also been reported in Japan, Singapore, Romania, Hungary and Italy. The prevalence of echinostomiasis varies between countries but there tend to be foci of infection in areas where raw or undercooked hosts of Echinostoma, such as snails or fish, are widely consumed.
I-143, Page 5 The general lack of collaboration between Pers Z S and Inspektorate 7 did not point to lack of coordination at senior administrative function, nor to professional jealously between the two agencies. Essentially the two agencies had two distinct operational foci. Pers Z S was diplomatic and OKH/Chi was a military agency. Therefore, there was little need for detailed collaboration.
Channel 24 airs two live interactive sports bulletins, called Sports 24, four times a day. The primary foci of the night bulletin are local and international sports events, including daily events, special reports, analyses and investigative reports. Match previews, point tables (graphics), key factors (graphics) and other analyses are displayed and discussed graphically. Each day includes a dedicated segment for one of the seven divisions of Bangladesh.
Diadenylate cyclase , DNA integrity scanning protein DisA is a DNA binding protein participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Catalytic activity : 2 ATP \rightleftharpoons 2 diphosphate + cyclic di-3',5'-adenylate. This enzyme has diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).
Chanel No. 19 contains fragrant notes of galbanum, neroli, bergamot, jasmine, rose, lily of the valley, iris, vetiver, sandalwood, leather and musk. The galbanum and leather on a musky base makes the scent very difficult to classify. Some call it a green floral, others a chypre. The different foci of each concentration (eau de cologne, eau de toilette, eau de parfum, parfum/extrait) also make classification difficult.
Single- unit recordings have provided tools to explore the brain and apply this knowledge to current technologies. Cognitive scientists have used single-unit recordings in the brains of animals and humans to study behaviors and functions. Electrodes can also be inserted into the brain of epileptic patients to determine the position of epileptic foci. More recently, single- unit recordings have been used in brain machine interfaces (BMI).
The granulomatous tissue largely comprises foam cells of monocyte/macrophage origin positive for KP1, HAM56, CD11b and CD68. Neutrophils, hemorrhagic foci and numerous plasma cells are additional findings. Staphylococcus aureus was isolated in the case reported by Kamat et al. A delayed type hypersensitivity reaction in cell-mediated immunity has been suggested in this type of infiltrate that is composed of macrophages and T cells.
As is evident from the characterization above, the field is not strictly limited to learning aspects; it is equally concerned with reasoning (specifically probabilistic inference) and knowledge representation. Therefore, alternative terms that reflect the main foci of the field include statistical relational learning and reasoning (emphasizing the importance of reasoning) and first-order probabilistic languages (emphasizing the key properties of the languages with which models are represented).
Only a small fraction of the estimated 1543 proteins in tears are differentially deficient or upregulated in dry eye, one of which is lacritin. Topical lacritin promotes tearing in rabbit preclinical studies. Also, topical treatment of eyes of dry eye mice (Aire knockout mouse model of dry eye) restored tearing, and suppressed both corneal staining and the size of inflammatory foci in lacrimal glands.
EBV positivity is more common in the plasmacytoma rather than bone marrow infiltration form of PCM. Tissues involved in EBV+ PCM typically show foci of EBV+ cells with the appearance of rapidly proliferating (e.g. high mitotic index) immature or poorly differentiated anplastic plasma cells. The cells express products of EBV genes such as EBER which suggest that EBV is in a restricted latency II phase.
Different foci in their extended foreign relations, however, did not preclude Iraq and Turkey from cooperating in common areas of interest. The Baghdad Pact is the evidence of the cooperation between two countries. On 24 February 1954, Iraq and Turkey signed a mutual- defense pact intended to contain the growth of Soviet influence in the region. Later, in 1955, Iran, Pakistan, and Britain had joined the pact.
The telescope is a 0.9 meter classical Cassegrain but with a third rotatable plane mirror sending light to one of the two Nasmyth foci. The effective system is an f/10 but the primary mirror is an f/3. The telescope was built by Astro Optic and there is a sibling telescope at Albonova in Stockholm. The telescope is one of the largest optical telescopes in Sweden.
The same zone plate will focus light of many wavelengths to different foci, which means they can also be used to filter out unwanted wavelengths while focusing the light of interest. Other waves such as sound waves and, due to quantum mechanics, matter waves can be focused in the same way. Wave plates have been used to focus beams of neutrons and helium atoms.
Histopathology of bronchopneumonia, showing neutrophils filling a bronchiole. Bronchopneumonia may sometimes be diagnosed after death, during autopsy. On gross pathology there are typically multiple foci of consolidation present in the basal lobes of the human lung, often bilateral. These lesions are 2–4 cm in diameter, grey-yellow, dry, often centered on a bronchiole, poorly delimited, and with the tendency to confluence, especially in children.
Accrington is a hill town located at the western edge of the Pennines within a bowl and largely encircled by surrounding hills to heights of 300-400m. The Hyndburn or Accrington Brook flows through the centre of the town. Hill settlements origins were as the economic foci of the district engaging in the spinning and weaving of woolen cloth. Wool, lead and coal were other local industries.
Mouse mutants with homozygous defects in Ku80 experience an early onset of senescence. Ku80(-/-) mice exhibit aging-related pathology (osteopenia, atrophic skin, hepatocellular degeneration, hepatocellular inclusions, hepatic hyperplastic foci and age-specific mortality). Furthermore, Ku80(-/-) mice exhibit severely reduced lifespan and size. Loss of only a single Ku80 allele in Ku(-/+) heterozygous mice causes accelerated aging in skeletal muscle, although post natal growth is normal.
The maximum field-of-view (at Nasmyth foci) is around 27 arcminutes diameter, slightly smaller than the full moon, though most instruments view a narrower field. Each telescope has an alt-azimuth mount with total mass around 350 tonnes, and uses active optics with 150 supports on the back of the primary mirror to control the shape of the thin (177mm thick) mirror by computers.
An optical system with astigmatism is one where rays that propagate in two perpendicular planes have different foci. If an optical system with astigmatism is used to form an image of a cross, the vertical and horizontal lines will be in sharp focus at two different distances. The term comes from the Greek α- (a-) meaning "without" and στίγμα (stigma), "a mark, spot, puncture".
But DNMT1 is unable to methylate cytosines during days 9.5 to 12.5 because the UHRF1 gene (also known as NP95) is repressed and UHRF1 is an essential protein needed to recruit DNMT1 to replication foci where maintenance DNA methylation takes place. This is a passive, dilution form of demethylation. In addition, from embryo day 9.5 to 13.5 there is an active form of demethylation.
The Hall of Ceremonies and the Neue Burg make up the backdrop of the square. Equestrian statues of the two most important Austrian field marshals, Prince Eugene of Savoy and Archduke Charles, stand at the foci of Heroes Square. On 15 March 1938 Adolf Hitler proclaimed from the balcony of the New Castle onto Heroes' Square the "Anschluss" of Austria into the Nazi Third Reich.
Proliferating cell nuclear antigen (PCNA) is a protein involved in post-replication MMR. It has been shown that PCNA binds to the MutSβ heterodimer via a binding motif in the N-terminal domain of MSH3. Bound PCNA then localizes the MutSβ complex to replication foci, indicating that PCNA assists in initiating repair by guiding MutSβ and other repair proteins to free termini in recently replicated DNA.
The main complex of FA contains a nuclear multi- subunit complex of notably 8 FA proteins. This adds a single ubiquiting chain to the FANCD2 following DNA damage or duplicative pressure. For the collection of FANCC, FANCE is important in the nucleus and gathering of the core complex. Some characteristics of FANCE is that it can set itself with ubiquitinated FANCD2, BRCA2 and constructed nuclear foci.
In Drosophila, anillin is necessary to organize myosin into rings in the cellularization front. Depletion of anillin in Drosophila and humans leads to changes in the spatial and temporal stability of myosin during cytokinesis. In C. elegans, ANI-1 organizes myosin into foci during cytokinesis and establishment of polarity, whereas, ANI-2 is a requirement for the maintenance of myosin-rich contractile lining of oogenic gonads.
Following the successful coup by the coalition of Bolingbroke and the Arundels, Burley's long-term client Hugh Burnell was one of the barons who accepted the surrender of Richard II at the Tower of London. Prestbury, the new abbot, and his abbey were to become foci for Burley's generosity as he prospered under the new Lancastrian régime and the restored Arundel supremacy in Shropshire.
Acute erosive gastritis typically involves discrete foci of surface necrosis due to damage to mucosal defenses. NSAIDs inhibit cyclooxygenase-1, or COX-1, an enzyme responsible for the biosynthesis of eicosanoids in the stomach, which increases the possibility of peptic ulcers forming. Also, NSAIDs, such as aspirin, reduce a substance that protects the stomach called prostaglandin. These drugs used in a short period are not typically dangerous.
Structured meanings allow for a compositional semantic approach to sentences that involve single or multiple foci. This approach follows Frege's (1897) Principle of Compositionality: the meaning of a complex expression is determined by the meanings of its parts, and the way in which those parts are combined into structured meanings. Krifka’s structured meaning theory represents focus in a transparent and compositional fashion it encompasses sentences with more than one focus as well as sentences with a single focus. Krifka claims the advantages of structured meanings are twofold: 1) We can access the meaning of an item in focus directly, and 2) Rooth's alternative semantics can be derived from a structured meaning approach but not vice versa. To see Krifka’s approach illustrated, consider the following examples of single focus shown in (10) and multiple foci shown in (11): (10) John introduced Bill to [SUE] f.
The top of the dome is 50m above ground level. The telescope tube structure is supported inside a massive 12m diameter horseshoe, which rotates around the polar axis (parallel to Earth's axis) for tracking the sky. Total moving mass is 260 tonnes. The telescope has various foci for flexible instrumentation: originally there were three top-end rings which can be exchanged using the dome crane during the daytime.
The tissues involved in EBV+ plasmacytoma typically show foci of EBV+ cells with the appearance of rapidly proliferating immature or poorly differentiated plasma cells. These cells express products of EBV genes such as EBER1 and EBER2. EBV-positive plasmacytoma(s) is more likely to progress to multiple myeloma than EBV-negative plasmacytoma(s) suggesting that the virus may play a role in the progression of plasmacytoma to multiple myeloma.
Arabidopsis thaliana cell in preprophase, prophase and prometaphase. Preprophase band is present along the cell wall from images 1-3, is fading in image 4, and disappears by image 5. The most notable difference between prophase in plant cells and animal cells occurs because plant cells lack centrioles. The organization of the spindle apparatus is associated instead with foci at opposite poles of the cell or is mediated by chromosomes.
Studies have found no role for antiarrhythmic agents, cardioversion, or anticoagulation. In the absence of underlying pulmonary disease, the first- line agent is beta-blockers. A beta-blockers act to suppress ectopic foci by reducing sympathetic stimulation and decreasing conduction through the atrioventricular node, thereby slowing the ventricular response. Studies have found an average decrease in heart rate of 51 beats per minute and 79% of patients reverted to sinus rhythm.
In 1996, the center was opened as the Advanced Engineered Wood Composites Center. In 2012, the organization formally underwent a name change as approved by the University of Maine System Board of Trustees to the Advanced Structures and Composites Center. This name change was a reflection of research foci expanded beyond wood composites to include other areas such as: ocean energy, defense and aerospace composites, civil infrastructure, and nanocomposites.
These two divisions of attention are continuously competing to be the momentary foci of attention. Selection models of attention theorize how specific stimuli gain our awareness. Early selection models emphasize physical features of stimuli are attended to, while late selection models argue that semantic features are what determine our current focus of attention. These selection models are utilized by researchers to propose when stimulus information is attended to.
Eastern civilization broadly includes Asia, and it also includes a complex tradition of art making. One approach to Eastern art history divides the field by nation, with foci on Indian art, Chinese art, and Japanese art. Due to the size of the continent, the distinction between Eastern Asia and Southern Asia in the context of arts can be clearly seen. In most of Asia, pottery was a prevalent form of art.
Writing in the Stanford Encyclopedia of Philosophy, Thomas D. Williams and Jan Olof Bengtsson cite a plurality of "schools" holding to a "personalist" ethic and "Weltanschauung", arguing: Thus, according to Williams, one ought to keep in mind that although there may be dozens of theorists and social activists in the West adhering to the rubric "personalism," their particular foci may, in fact, be asymptotic, and even diverge at material junctures.
SCCWRP’s research foci include collaborative regional environmental monitoring, development of assessment tools to characterize environmental conditions, and modeling and analysis to answer relevant environmental management questions. Significant research topics include regional monitoring of the Southern California Bight, beach water quality, hydromodification, wetlands, eutrophication, marine debris, and contaminants of emerging concern.Panel on Southern California Bight of the Committee on a Systems Assessment of Marine Environmental Monitoring (1990). Monitoring Southern California's Coastal Waters.
The Lohrer Schloss Small churchyard gate The ' houses the Spessartmuseum. It deals mainly with economics and handicrafts, but also with the Spessart's regional history. In the outlying centre of Sendelbach is a school museum with the foci '"Imperial Germany" (1871-1918) and "Third Reich" (1933-1945). Germany's smallest museum is to be found on Haaggasse in a former transformer hut under monument protection, it shows all kinds of insulators.
The Elginfield Observatory is an astronomical observatory located in the township of Middlesex Centre, Ontario (Canada), about north of London, Ontario. The observatory is owned and operated by the University of Western Ontario, and opened in 1969. The observatory features a Ritchey–Chrétien telescope built by Boller and Chivens which is used for spectroscopy and photometry. The telescope can be configured to feed instruments at the Cassegrain, Nasmyth, and Coudé foci.
However, if it's caused by problems with development in the heart – if Gata5 did not express properly in the embryo- then this can lead to constant ectopic foci problems. These problems include tachycardia (the heart beating too fast), bradycardia (the heart beating too slow), or ventricular fibrillation which is a serious condition where the ventricles of the heart aren't pumping consistently and can't get blood out to the body.
716-731 Considerable debate continues in anthropology over the role of postmodernism and reflexivity, but most anthropologists accept the value of the critical perspective, and generally only argue about the relevance of critical models that seem to lead anthropology away from its earlier core foci. The second kind of reflexivity studied by anthropologists involves varieties of self- reference in which people and cultural practices call attention to themselves.BARBARA A. BABCOCK.
There are several subtypes of endometrioid adenocarcinoma with similar prognoses, including villoglandular, secretory, and ciliated cell variants. There is also a subtype characterized by squamous differentiation. Some endometrioid adenocarcinomas have foci of mucinous carcinoma. The genetic mutations most commonly associated with endometrioid adenocarcinoma are in the genes PTEN, a tumor suppressor; PIK3CA, a kinase; KRAS, a GTPase that functions in signal transduction; and CTNNB1, involved in adhesion and cell signaling.
The primary focus is located 15 metres from the parabolas vertex and is coincident with one of the foci of the secondary. The entire primary reflector and support structure weighs 200 tons. The Secondary Reflector :M2 is the hyperbolic sub-reflector of the dual reflector Cassegrain system and has a diameter of 3.28 metres. It is made from a carbon fibre shell covered in a thin layer of aluminium foil.
The ship is a registered National Historic Landmark. In Honolulu, Foss Marine, The Honolulu Pilots Association and others are offering their services and staff to support the operation. FOCI currently have an agreement in place with another lift ship company (Roll Dock) to take the FOC home in June 2020. However, due to the coronavirus outbreak, this is unlikely and the job has been pushed back to September 2020.
The catchment area is composed of gently undulating saline stony plains with associated internal drainage lines and several scattered drainage foci. The lake is situated on major ancient drainage lines and has massive supplies of saline water from sand aquifers at the base of the paleochannels from depths of . Annually the catchment receives rainfall of and has an evaporation rate . The main land uses around Lake Austin are mining and pastoralism.
CLOCK protein has been found to play a central role as a transcription factor in the circadian pacemaker. In Drosophila, newly synthesized CLOCK (CLK) is hypophosphorylated in the cytoplasm before entering the nucleus. Once in the nuclei, CLK is localized in nuclear foci and is later redistributed homogeneously. CYCLE (CYC) (also known as dBMAL for the BMAL1 ortholog in mammals) dimerizes with CLK via their respective PAS domains.
It was during the time the timber trackway was built that the local environment began to change. Previous paleo-environmental studies on the moor indicate peat growth began around 3000BC. The radiocarbon date from the east of the site of 5470-5220 cal. BC is the earliest available on Hatfield Moor for wetland inception and indicated the northern part of Hatfield Moor was one of the earliest foci for peat formation.
This is followed by a thorough explanation of each aspect (aṅga) of the four absorptions (catvāri dhyānāni). Also, various related terms from the scriptures are discussed.Kragh 2013, pp. 80-81. The third section provides a classification of the various types of meditation, these types are either divided into different forms of 'observation' (manasikāra) or classified according to the various foci (ālambana) on which one concentrates, which are called the 'images' (nimitta).
The Decca Navigator principle. The phase difference between the signals received from stations A (Master) and B (Slave) is constant along each hyperbolic curve. The foci of the hyperbola are at the transmitting stations, A and B. The Decca Navigator System consisted of a number of land-based radio beacons organised into chains. Each chain consisted of a master station and three (occasionally two) secondary stations, termed Red, Green and Purple.
The website publishes many submitted news and press releases due to their permissive policy. Their website states: "If it's a press release issued in New Zealand, is legible, legal, sane, not hateful and not defamatory we will most probably publish it." In addition to being a general news website, Scoop also contains sub-sites with specific foci: Wellington.scoop, which aggregates Wellington-specific news with editorial comment, and also Pacific.
Naidu, R., & Venugopal, M. N. (2007). Epidemiology of'Katte'virus disease of small cardamom-II: Foci of primary disease entry, patterns and gradients of disease entry and spread. Along with P. caladii, various other species of aphid have been reported to transmit the virus. The virus can be transmitted by both the nymphal and the adult stages, but efficiency increases with age of the vector; alate and apterous form are the most efficient.
To date, hundreds of studies on miscue analysis have been conducted from different perspectives to explore the reading process, to evaluate readers, and to improve reading instruction (Brown, Goodman, & Marek, 1996). Although their foci are different, these studies have generally confirmed Goodman's model and theory of reading view that reading is a meaning-seeking process in which readers use graphic, phonemic, syntactic, and semantic cues to make sense of texts.
It also publishes Earth Surface Exchanges which include commentaries on issues of particular geomorphological interest, discussions of published papers, shorter journal articles suitable for rapid publication, and commissioned reviews on key aspects of geomorphological science. Foci include the physical geography of rivers, valleys, glaciers, mountains, hills, slopes, coasts, deserts, and estuary environments, along with research into Holocene, Pleistocene, or Quaternary science. The editor-in-chief is Stuart Lane (University of Lausanne).
Metanephric adenoma is diagnosed histologically. The tumours can be located at upper pole, lower pole and mid-hilar region of the kidney; they are well circumscribed but unencapsulated, tan pink, with possible cystic and hemorrhagic foci. They show a uniform architecture of closely packed acinar or tubular structures of mature and bland appearance with scanty interposed stroma.Bostwick DG, Eble JN (2008) Urologic Surgical Pathology. St Louis, Mosby, p118.
Chandra is one of the Great Observatories, along with the Hubble Space Telescope, Compton Gamma Ray Observatory (1991-2000), and the Spitzer Space Telescope (2003-2020). The telescope is named after the Nobel Prize-winning Indian astrophysicist Subrahmanyan Chandrasekhar. Its mission is similar to that of ESA's XMM-Newton spacecraft, also launched in 1999 but the two telescopes have different design foci; Chandra has much higher angular resolution.
Cellular DNA is regularly exposed to DNA damaging agents. A DNA damage response (DDR) that is well regulated and intricate is usually employed to deal with the potential deleterious effects of the damage. When DNA damage occurs, SUMO protein has been shown to act as a molecular glue to facilitate the assembly of large protein complexes in repair foci. Also, SUMOylation can alter a protein's biochemical activities and interactions.
The extrafascial part is composed of fatty overgrowth, phlebectasia, and occasional lymphatic malformation. The histopathologic findings in FAVA include dense fibrous tissue, fat, and lymphoplasmacytic aggregates within atrophied skeletal muscle. Adipose tissue within skeletal muscles are associated with large, irregular, and sometimes excessively muscularized venous channels and smaller, clustered channels. Organizing thrombi, lymphatic foci and enlarged nerves encircled by dense fibrous tissue are also frequently noted in FAVA.
In an early article, Holloway and Valentine termed these 'spatial discourses' Children's geographies can be observed through the various lenses provided by foci, thus the plurality inspired by post-modern and post-structural social geographers (Panelli, 2009)., Panelli, 2009. Approaches to Human Geography. These foci include, but are not limited to: the history of its emergence (key authors and texts), the nature of the child (geographical concepts, family contexts, society contexts, gender variation, aged-based variation, cultural variation), children in the environment (home, school, play, neighbourhood, street, city, country, landscapes of consumption, cyberspace), designing environments for children (children as planners, utopian visions), environmental hazards (traffic, health and environment, accidents), indirect experience of place (not medium specific, literature, T.V. and cyberspace), social issues (children's fears, parent's fears for their children, poverty and deprivation, work, migration, social hazards, crime and deviance), citizenship and agency (environmental action, local politics, interest in the environment), and children's geographical knowledge (environmental cognition, understanding the physical environment) (McKendrick, 2000).
Focal degeneration causes a localized attack of the host cell monolayer. Although this type of CPE may eventually affect the entire tissue, the initial stages and spreading occur at localized viral centers known as foci. Focal degeneration is due to direct cell-to-cell transfer of the virus rather than diffusion through the extracellular medium. This different mode of transfer differentiates it from total and subtotal destruction and causes the characteristic localized effects.
Although the products of this metabolism are mostly safe, there are some toxic byproducts that can damage DNA. In the promotion phase, tumors grow from tiny clusters of cells called foci. This phase is reversible, depending on the balance between promoters that feed growth and anti-promoters that inhibit it. Finally, progression is the spreading of the cancer from its source to neighboring parts of the body, at which point it is considered malignant.
Along with the Koshkonong and Green Bay Foci, the Grand River Focus is considered part of the Developmental Horizon of the Oneota Aspect, dating to approximately A.D. 1000-1300. The radiocarbon dates obtained from the Walker-Hooper site accordingly range from A.D. 1200-1240. The site is thought to have been occupied during a relatively short interval. Based upon the animal and plant remains, it is thought to have been a summer seasonal agricultural village.
A nuclear complex containing FANCL (as well as FANCA, FANCB, FANCC, FANCE, FANCF, FANCG and FANCM) is essential for the activation of the FANCD2 protein to the mono-ubiquitinated isoform. In normal, non-mutant, cells FANCD2 is mono-ubiquinated in response to DNA damage. Activated FANCD2 protein co-localizes with BRCA1 (breast cancer susceptibility protein) at ionizing radiation-induced foci and in synaptonemal complexes of meiotic chromosomes (see Figure: Recombinational repair of double strand damage).
L. Xiang, L. Ji, T. Zhang, B. Wang, J. Yang, Q. Zhang, M.S. Jiang, J. Zhou, P.R. Carney, H. Jiang, "Noninvasive real time tomographic imaging of epileptic foci and networks", Neuroimage 66 (2013) 240-248.S. Gottschalk, T. Felix Fehm, X. Luís Deán-Ben, D. Razansky, "Noninvasive real-time visualization of multiple cerebral hemodynamic parameters in whole mouse brains using five-dimensional optoacoustic tomography", J. Cereb. Blood Flow Metab. 35 (2015) 531-535.
The RNS System was evaluated in a multi-center, prospective, randomized, controlled, double-blinded clinical study. The study included adults who have medically refractory, partial onset seizures with up to two localized seizure foci, and who had failed at least two medications. In total, 191 patients were randomized 1:1 to either treatment with the RNS System or sham stimulation. After the four month blinded period, stimulation was turned on for all patients.
This has been generally based on the clinical appearance of the inflamed mucosa seen under maxillary complete dentures. The classification of Newton (1962) has been the most widely used. He proposed three types: (1) Pinpoint hyperaemic foci, (2) Diffuse hyperaemia of denture-supporting tissues, and (3) Papillary hyperplasia. Budtz-Jorgensen & Bertram (1970) used different terminology for the same changes: (1) Simple localized inflammation, (2) Simple diffuse (generalized) inflammation, and (3) Granular inflammation.
He was appointed Full Professor of Biomedical Image Processing in the Departments of Radiology and Medical Informatics at the Erasmus University Medical Center in 2005. His research foci include computer vision, biomedical image analysis, and computer assisted interventions. He was also appointed Professor at Delft University of Technology at the faculty of Applied Sciences the same year. In 2017 he was elected a member of the Royal Netherlands Academy of Arts and Sciences.
Flunixin is administered at a dose of 1.1 mg/kg. The full analgesic and antipyretic effects usually occur 1–2 hours following treatment, but there is often an effective analgesic effect within approximately 15 minutes. Despite its short plasma half life of 1.6-2.5 hours, effects can persist for up to 30 hours, with maximal effects occurring between 2 and 16 hours. This is likely due to accumulation of the drug at inflammatory foci.
Also, Four Star Productions leased the lot for many of its series like The Rifleman, Dick Powell's Zane Grey Theater, and The Big Valley. Republic Pictures ceased production in 1958 and Victor M. Carter became its president in 1959. Carter built Republic into a diversified business with foci outside of the television and film business, and so began leasing its lot to CBS. In 1963, CBS Television became the primary lessee of the lot.
From 1962 until 1971 Anhalt reworked, consolidated and expanded his experiences during the two previous periods. He combined electronic sounds with the sounds of the chorus or the orchestra in his Symphony of Modules, Foci, and Cento. Anhalt also adopted a more flexible syntax, as well as a larger musical vocabulary to create new vocal and instrumental sounds. He began to use timbre, timing, and musical densities in new ways in his compositions.
Adenomyomatosis of the gallbladder as seen on ultrasound Non-contrast abdominal ultrasound and contrast-enhanced ultrasound (CEUS) of adenomyomatosis of the gallbladder: a The fundus of the gallbladder wall was thickened and the GB wall was obscure. b The intramural echogenic foci were detected by high frequency transducer. c CEUS—arterial phase (22 s) —heterogeneous hyper-enhancement and wall was intact. d CEUS—venous phase (34 s) the anechoic spaces were more clear.
According to Kozinets, any netnography will fall into one of four categories: auto, symbolic, digital or humanist. These types of netnography are defined by distinctive axiologies and foci. In order to visualize how a netnography is defined one should Imagine a simple 2X2 figure. Along the figure's x-axis we see that a netnography can be defined by whether or not it supports or challenges the status quo of business and management.
The Steiner inellipse of a triangle can be generalized to n-gons: some n-gons have an interior ellipse that is tangent to each side at the side's midpoint. Marden's theorem still applies: the foci of the Steiner inellipse are zeroes of the derivative of the polynomial whose zeroes are the vertices of the n-gon.Parish, James L., "On the derivative of a vertex polynomial", Forum Geometricorum 6, 2006, pp. 285–288: Proposition 5.
His foci are on affordances of communication and in older and newer media, which he studies in contexts of contemporary travel, tourism, museums, and political activism. Noy has written three books, published over 80 academic publications, as well as contributed numerous conference papers. For his book, Thank You for Dying for Our Country: Commemorative Texts and Performances in Jerusalem (Oxford University Press, 2015), Noy received the Best Book Award by the Israeli Communication Association.
In the initial phase of the infection, early transformed schistosomula are localised in the skin. Information about pathology in the skin of birds has not been completed yet. In mice, immediate oedema and thickening of the site appear as early as 30 minutes after the penetration of cercariae; erythema is evident as well. Within 48 hours, inflammatory foci containing neutrophils, eosinophils, macrophages, CD4+ lymphocytes and degranulating mast cells develop around the parasites.
The principle of ellipsographs were known to Greek mathematicians such as Archimedes and Proklos. If there is no ellipsograph available, one can draw an ellipse using an approximation by the four osculating circles at the vertices. For any method described below, knowledge of the axes and the semi-axes is necessary (or equivalently: the foci and the semi-major axis). If this presumption is not fulfilled one has to know at least two conjugate diameters.
The principal points are the points where the principal planes cross the optical axis. If the medium surrounding the optical system has a refractive index of 1 (e.g., air or vacuum), then the distance from the principal planes to their corresponding focal points is just the focal length of the system. In the more general case, the distance to the foci is the focal length multiplied by the index of refraction of the medium.
This exemplifies the shift away from the earlier focus on burial mounds as the monumental foci of communities lacking large settlements to the later emphasis on platform mounds at the center of towns. Mississippians decentralized cemeteries, making their communities rather than their burial places the center of their lives. "One group of four Mississippian people buried together appear to have been sacrificed at the Dickson Site". Their heads were removed and replaced by pots.
T. cacao is widely distributed from southeastern Mexico to the Amazon basin. There were originally two hypotheses about its domestication; one said that there were two foci for domestication, one in the Lacandon Jungle area of Mexico and another in lowland South America. More recent studies of patterns of DNA diversity, however, suggest that this is not the case. One study sampled 1241 trees and classified them into 10 distinct genetic clusters.
A short History of the development of Ultrasound in Obstetrics and Gynecology With the Center for Bioengineering, Dr. Rushmer aimed to develop a joint research enterprise of the UW College of Engineering and UW School of Medicine to study the cardiovascular system. As its research foci expanded, the Center received the ability to grant PhD degrees in 1984. Undergraduate courses were added in 1985. The Center became the Department of Bioengineering in 1997.
Like many neighbourhoods found within Toronto, there is always a correlation between districts as well as nodes. In other words, where there are nodes, then there most likely will be a district. In further depth, a node can be defined as strategic foci into which the observer can enter, typically either through junctions of paths, or concentrations of some characteristic. On the other hand, districts can be defined as areas that have some common character.
Micrograph of a H&E; stained tissue section showing a non-absorbable multi- filament surgical suture with a surrounding foreign-body giant cell reaction Suture thread is made from numerous materials. The original sutures were made from biological materials, such as catgut suture and silk. These absorbed bodily fluids and could be foci of infection. Founder of gynecology J. Marion Sims invented the use of silver wire, which is anti-bacterial, for a suture.
He contributed to structural operational semantics and verification technology. His particular contributions include the tyft/tyxt format for operational rules, the first algorithm to determine branching bisimulation and the cones and foci method to prove correctness of protocols and distributed algorithms. He is the founding godfather of the process modelling language and analysis tool sets muCRL and mCRL2. He began working in 2000 as a full professor in verification technology at Eindhoven University of Technology.
Each Comunidad is a territorial and political unit. At the center of a Comunidad is a main town that is the religious-political center for the surrounding anexos (named villages) and isolated rancherías belonging to the Comunidad. A ranchería consists of clustered houses surrounded by widely scattered small farm plots. The towns act as central foci for government, social, and religious rituals and are official headquarters for holding elections and discussing matters affecting the Comunidad.
No hinterland creates for low archaeological visibility. The settlement must also have access to both easy transportation and major interregional trade routes, crucial in a region with few resources. Access to the former and later played a major role in the creation of an extreme economic surplus in the absence of an exploited hinterland. The urban center must be able to organize politically without the need for ceremonial foci such as temples, monuments and inscriptions.
The first reported human infection was in Taiwan in 1929. The prevalence of Echinostoma revolutum trematodes in Taiwan during 1929–1979 varied from 0.11% to 0.65%. Small Echinostoma revolutum–endemic foci or a few cases of human infection were discovered in the People's Republic of China, Indonesia, and Thailand until 1994. However, no information is available about human Echinostoma revolutum infection after 1994, even in areas where the parasite was previously endemic.
It is regarded, along with Takka Takka as "successful in their combination of brilliant color and narrative situation". Blam is a jest with the viewer that uses an exclamation without narrative context. Like Blang (1962) and Varoom (1963), Blam's onomatopoeia explodes "like a violent central sun over the entire composition". Lichtenstein has revised the original source so that the aircraft and its explosion are the joint foci from which the painting radiates.
During the late 1970s, the Abalone Alliance organized protests in San Luis County and regularly picketed PG&E; offices across the state. The Alliance published a newspaper, It's About Times, which provided a forum for activist debate. Separate groups within the Abalone coalition "developed their own foci and protest styles". On August 7, 1977, 1,500 people demonstrated at the gate of Diablo Canyon, resulting in 47 arrests. The next year, 5,000 people rallied and 487 were arrested.
Ectopic beats are more common during periods of stress, exercise or debility; they may also be triggered by consumption of some food like alcohol, strong cheese, or chocolate. It is a form of cardiac arrhythmia in which ectopic foci within either ventricular or atrial myocardium, or from finer branches of the electric transduction system, cause additional beats of the heart. Some medications may worsen the phenomenon. Ectopic beats are considered normal and are not indicative of cardiac pathology.
Ellipsoidal coordinates The parametric latitude can also be extended to a three-dimensional coordinate system. For a point not on the reference ellipsoid (semi-axes and ) construct an auxiliary ellipsoid which is confocal (same foci , ) with the reference ellipsoid: the necessary condition is that the product of semi-major axis and eccentricity is the same for both ellipsoids. Let be the semi-minor axis () of the auxiliary ellipsoid. Further let be the parametric latitude of on the auxiliary ellipsoid.
Johannes Kepler extended the theory of conics through the "principle of continuity", a precursor to the concept of limits. Kepler first used the term foci in 1604. Girard Desargues and Blaise Pascal developed a theory of conics using an early form of projective geometry and this helped to provide impetus for the study of this new field. In particular, Pascal discovered a theorem known as the hexagrammum mysticum from which many other properties of conics can be deduced.
This resulted in suppression of lytic infection. Ezh1/2 inhibitors also activate cellular antiviral pathways. Specifically, in cells treated with Ezh1/2 inhibitors, greater numbers of promyelocytic leukemia (PML) foci, which are involved with repression of gene expression, were seen, along with upregulation of interferon-alpha (IFN-α) and interleukin-8 (IL-8). These pathways are not specific to HSV; treatment with Ezh1/2 inhibitors reduced infection of multiple viral pathogens, including human cytomegalovirus, adenovirus, and Zika virus.
The plague resurfaced for a third time in the mid-19th century. Like the two previous outbreaks, this one also originated in Eastern Asia, most likely in Yunnan Province of China, where there are several natural plague foci. The initial outbreaks occurred in the second half of the eighteenth century. The disease remained localized in Southwest China for several years before spreading. In the city of Canton, beginning in January 1894, the disease killed 80,000 people by June.
In 1920, after the establishment of Soviet power in Azerbaijan, the Main Railway Workshops were transferred to the administration of the Transcaucasian Railway. The production of oil equipment ceased and the factory became an enterprise working for the railway. Its main foci became locomotive repair, production of spare parts for rolling stock and repair of line equipment, subordinated to servicing enterprise-pumping stations, power stations and locomotive depots. After 1933, the factory specialized in the repair of oil tankers.
A wide variety of curricula are employed in the service of each of these rubrics. Occasionally, the gap between American Studies and Ethnic Studies can be productively bridged, especially in departments where the bulk of faculty focus on race and ethnicity, difference and power. But that bridgework can be troublesome, obscuring one foci and sharpening the emphasis on another. As a consequence of this great variation, though, ethnic studies needs to be understood within its specific institutional context.
Philadelphia: Saunders Elsevier. pp. 500–501. . Foam cells form the fatty streaks of the plaques of atheroma in the tunica intima of arteries. Foam cells are not dangerous as such, but can become a problem when they accumulate at particular foci thus creating a necrotic centre of atherosclerosis. If the fibrous cap that prevents the necrotic centre from spilling into the lumen of a vessel ruptures, a thrombus can form which can lead to emboli occluding smaller vessels.
The principal possible indicators of movement toward an individualized conception of security lie in the first place in the evolution of international society's consideration of rights of individuals in the face of potential threats from states. The most obvious foci of analysis here are the UN Charter, the UN Declaration of Human Rights (1948) and its associated covenants (1966), and conventions related to particular crimes (e.g.,genocide) and the rights of particular groups (e.g., women, racial groups, and refugees).
During the first two years as president there were two main foci of violence in the country; in Boyaca and Santander initially motivated by political reasons. The towns with most problems were Chiquinquirá, the towns of western Boyaca, the Garcia Rovira Province in Santander Department and some towns in the areas of Norte de Santander Department, where conservative public employees resisted being in charge of liberals until the end of his government on August 7, 1934.
An article also ran in The Heights profiling a college student from Iran at Boston College, and a campus meeting about the religion. In 1988 the national assembly of the United States picked Boston among its four foci for expansion of the religion and a conference of some 800 Baháʼís gathered. In 1990 the Boston Baháʼís move their Center to 495 Columbus Avenue and it is moved again in 1993 to its current location at 595 Albany Street.
The width and height parameters a,\; b are called the semi-major and semi-minor axes. The top and bottom points V_3 = (0,\, b),\; V_4 = (0,\, -b) are the co-vertices. The distances from a point (x,\, y) on the ellipse to the left and right foci are a + ex and a - ex. It follows from the equation that the ellipse is symmetric with respect to the coordinate axes and hence with respect to the origin.
Given two points p1 and p2 and two lines l1 and l2, there is a fold that places p1 onto l1 and p2 onto l2. Image:Huzita axiom 6.png This axiom is equivalent to finding a line simultaneously tangent to two parabolas, and can be considered equivalent to solving a third-degree equation as there are in general three solutions. The two parabolas have foci at p1 and p2, respectively, with directrices defined by l1 and l2, respectively.
The genesis of their cooperation is unclear, but it may have started before mid-1911. Tri and Hiep were said to have been in awe when Sanh produced a golden plaque that read "heir to the throne". The men agreed that the geographical foci of their movement would be in Cholon and Tan An in Vietnam and Kampot in Cambodia. The trio decided to model their actions on an uprising that had occurred in Kampot in 1909.
A circular orbit is a special case, wherein the foci of the ellipse coincide. The point where the orbiting body is closest to Earth is called the perigee, and is called the periapsis (less properly, "perifocus" or "pericentron") when the orbit is about a body other than Earth. The point where the satellite is farthest from Earth is called the apogee, apoapsis, or sometimes apifocus or apocentron. A line drawn from periapsis to apoapsis is the line-of-apsides.
Reaction to Danish and French nationalism provided foci for expressions of German unity. Military successes—especially those of Prussia—in three regional wars generated enthusiasm and pride that politicians could harness to promote unification. This experience echoed the memory of mutual accomplishment in the Napoleonic Wars, particularly in the War of Liberation of 1813–14. By establishing a Germany without Austria, the political and administrative unification in 1871 at least temporarily solved the problem of dualism.
For any given elapsed time difference, there is an infinite number of locations that match that delay. When plotted, these points form an ellipse with the CH station at one foci and the KH receiver at the other. Today, this is known as the bistatic range. To aid plotting these locations, each set of ten numbers on the circular scale, say 100 to 110, was assigned to a pre-calculated ellipse, in this case "ellipse 10".
However, exactly the same is reported of Dale (Stanley Park) Abbey, where the abbot's jurisdiction over probate and marriage were inherited, asserted and exercised after the dissolution by lay lords of the manor, who took the title "lay bishop," until the mid-19th century. The jurisdiction was rooted in the Premonstratensian privilege of independence from the local bishop. See . However, the foci of conflict were generally not related to the abbots' ecclesiastical authority but to their practices as landlord.
Hypatia theorizes that the Earth orbits around the Sun in an elliptic orbit, not a circular orbit, with the Sun at one of the foci. Cyril convinces a mob of Christians that Hypatia is a witch, and they vow to kill her. Davus tries to run ahead to warn Hypatia, but she is captured. They strip Hypatia and are about to skin her alive until Davus persuades the mob otherwise, and they decide to stone her instead.
In 1979, Exodus International's co-founder Michael Bussee and his partner, Gary Cooper quit the group and held a life commitment ceremony together.Their story is one of the foci of the documentary One Nation Under God (1993), directed by Teodoro Maniaci and Francine Rzeznik. On June 27, 2007, Bussee, along with fellow former Exodus leaders Jeremy Marks and Darlene Bogle, issued a public apology for their roles in Exodus. Exodus disbanded as an organization on June 20, 2013.
Otosclerosis is a condition where one or more foci of irregularly laid spongy bone replace part of normally dense enchondral layer of bony otic capsule in the bony labyrinth. This condition affects one of the ossicles (the stapes) resulting in hearing loss, tinnitus, vertigo or a combination of symptoms. The term otosclerosis is something of a misnomer. Much of the clinical course is characterized by lucent rather than sclerotic bony changes, so the disease is also known as otospongiosis.
It seems that the lesions go through an active "spongiotic" or hypervascular phase before developing into "sclerotic" phase lesions. There have been many genes and proteins identified that, when mutated, may lead to these lesions. Also there is mounting evidence that measles virus is present within the otosclerotic foci, implicating an infectious etiology (this has also been noted in Paget's Disease). CHL in otosclerosis is caused by two main sites of involvement of the sclerotic (or scar-like) lesions.
Ductal carcinoma in situ (DCIS) literally means groups of "cancerous" epithelial cells which remained in their normal location (in situ) within the ducts and lobules of the mammary gland. Clinically, it is considered a premalignant (i.e. potentially malignant) condition, because the biologically abnormal cells have not yet crossed the basement membrane to invade the surrounding tissue. When multiple lesions (known as "foci" of DCIS) are present in different quadrants of the breast, this is referred to as "multicentric" disease.
He noted that the center of a circle tangent to both given circles must lie on a hyperbola whose foci are the centers of the given circles. To understand this, let the radii of the solution circle and the two given circles be denoted as rs, r1 and r2, respectively (Figure 3). The distance d1 between the centers of the solution circle and C1 is either or , depending on whether these circles are chosen to be externally or internally tangent, respectively.
Inbound ships, cargo and personnel require clearance by four main government bodies: China Customs for customs declaration, Border Inspection for migration formalities, China Inspection and Quarantine for quarantine and fumigation, and the MSA for ship and crew safety regulations. Obtaining clearance from these so-called "One Customs Three Inspections" (一关三检) used to be a protracted process, and one of the continued foci of port reform is to speed up the clearance procedures and reduce their (still significant) burden.
But DNMT1 is unable to methylate cytosines during days 9.5 to 12.5 because the UHRF1 gene (also known as NP95) is repressed and UHRF1 is an essential protein needed to recruit DNMT1 to replication foci where maintenance DNA methylation takes place. This is a passive, dilution form of demethylation. In addition, from embryo day 9.5 to 13.5 there is an active form of demethylation. As indicated below in "Molecular stages of active reprogramming," two enzymes are central to active demethylation.
In 1985, a planning committee recommended the creation of a new college at UC San Diego focused on comparative cultural and historical studies to augment its four existing undergraduate colleges and their different general education foci. The Academic Senate approved the proposal in May 1986 and James Lyon was appointed founding provost of Fifth College in March 1987. UCSD's colleges receive a numeric designation until a permanent name is later chosen. In fall 1988, Fifth College welcomed its inaugural class.
1) complex, one of the central factors of the replication checkpoint. This interaction is mediated by the binding of the RAD1 subunit to the N-terminal region of WRN and is instrumental for WRN relocalization to nuclear foci and its phosphorylation in response to replication arrest. (In the absence of DNA damage or replication fork stalling, WRN protein remains localized to the nucleoli.) The interaction of WRN with the 9.1.1 complex results in prevention of DSB formation at stalled replication forks.
In this process, an ATP dependent DNA strand exchange takes place in which a single strand invades base-paired strands of homologous DNA molecules. RAD51 is involved in the search for homology and strand pairing stages of the process. This gene encodes a protein that functions in genome maintenance (double strand break repair). This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.
Paternal transmission of the congenital form is uncommon (13%), possibly due to selection pressures against sperm with expanded repeats, but juvenile or adult onset is equally transmitted from either parent. Anticipation tends to be less severe than in cases of maternal inheritance. The RNA from the expanded trinucleotide repeat region forms intranucleoplasmic hairpin loops due to the extensive hydrogen bonding between C-G base pairs, and it has been demonstrated that these sequester the splicing regulator MBNL1 to form distinctive foci.
The 60-inch Hale telescope (1.5 m), Hooker Telescope, 200-inch Hale Telescope, Shane Telescope, and Harlan J. Smith Telescope all were built with coudé foci instrumentation. The development of echelle spectrometers allowed high- resolution spectroscopy with a much more compact instrument, one which can sometimes be successfully mounted on the Cassegrain focus. Since inexpensive and adequately stable computer-controlled alt-az telescope mounts were developed in the 1980s, the Nasmyth design has generally supplanted the coudé focus for large telescopes.
The Agora Virtual Environment Center (AVEC) conducts research in the fields of computer graphics and virtual reality. It also offers visualisation and graphics programming services to various departments within the University of Jyväskylä and to companies. AVEC also arranges seminars and lecture courses. The foci of AVEC are virtual reality applications, interactions in virtual environments, and programming architectures for virtual reality applications. When selecting and implementing research topics, AVEC’s management emphasizes issues that have technical, financial, and/or scientific significance.
The original magic system had specific formulae for each spell that the caster had to discover through trial and error. Magic was challenging and rare. This system of spell components was later phased out and replaced with a simpler system wherein magic casters would carry a "foci" for each of the magic schools they were trained in (creature, item, life and war) and a series of taper candles and scarabs. Each spell is learned from a scroll, either purchased or found as treasure.
Diagram of brain – topography of the main groups of foci in the motor field of chimpanzee Chimpanzees make tools and use them to acquire foods and for social displays; they have sophisticated hunting strategies requiring cooperation, influence and rank; they are status conscious, manipulative and capable of deception; they can learn to use symbols and understand aspects of human language including some relational syntax, concepts of number and numerical sequence; and they are capable of spontaneous planning for a future state or event.
When there are multiple epileptic foci or the focus cannot be localized, and drug therapy is not effective, vagus nerve stimulation is another option for treating PTE. People with PTE have follow-up visits, in which health care providers monitor neurological and neuropsychological function and assess the efficacy and side effects of medications. As with sufferers of other types of epilepsy, PTE sufferers are advised to exercise caution when performing activities for which seizures could be particularly risky, such as rock climbing.
Alpha-synuclein modulates DNA repair processes, including repair of double-strand breaks (DSBs). DNA damage response markers co-localize with alpha-synuclein to form discrete foci in human cells and mouse brain. Depletion of alpha-synuclein in human cells causes increased introduction of DNA DSBs after exposure to bleomycin and reduced ability to repair these DSBs. In addition, alpha- synuclein knockout mice display a higher level of DSBs, and this problem can be alleviated by transgenic reintroduction of human alpha-synuclein.
British Archaeology The role of megaliths as monuments and foci of ceremony and celebration, as well as markers on the landscape is emphasised by archaeologists such as Richard Bradley; but they were also memorials to particular lineages and possibly individuals from elite groups. Carrowmore represents a foundation point and a centre point in a Neolithic landscape.Hensey, Robert; Meehan, Pádraig; Dowd, Marion and Moore, Sam. A century of archaeology—historical excavation and modern research at the Carrowkeel passage tombs, County Sligo.
Uncle William Creech donated of land to establish Pine Mountain Settlement School, the first educational institution in the area. The school was co-founded in 1913 by Katherine Pettit and Ethel de Long Zande and was designed by architect Mary Rockwell Hook. Pine Mountain Settlement School has served many purposes, though its current foci are Appalachian cultural education and environmental education. As Creech said in a letter from 1915, > I have heart and cravin' that our people may grow better.
Throughout his life, Flanders underwent changes to his political affiliations and foci. His political and intellectual development began with a focus on socialism, so much so that he migrated to Germany to join the ISK and pursue his interest in the topic through learning at the organization’s Walkemuhle, or training school at 18, in 1929.Kelly, 7. He continued to pursue and write on anti- Marxist, Leninist socialism for decades until the postwar 1940s when he worked for the UK government.
The framework is infilled with face brick, except in the sanctuary where marble is used. The building finishes were left unpainted to reduce future maintenance liability and the flooring chosen was durable marble, terrazzo, mosaic and linoleum. Liturgical foci – the altar, baptismal font and holy water fonts – are constructed in solid Botticeno marble. The canopy over the high altar is constructed of edge-grained Oregon Pine with Sapele Mahogany fascias, in the form of a hyperbolic paraboloid supported on laminated Sapele Mahogany columns.
The WHT is equipped with a wide range of scientific instruments, providing astronomers with the capabilities to conduct a large variety of scientific investigations. , the current common-user instrumentation is: ;ACAM :Auxiliary-port CAMera – optical imager/spectrograph, with broad- and narrow-band imaging over an 8' field and low-resolution (R < 900) spectroscopy. Permanently mounted at one of the broken-Cassegrain foci. ;ISIS :Intermediate dispersion Spectrograph and Imaging System – medium resolution (R = 1,800-20,000) long-slit dual-beam optical spectrograph.
The work, of 1846, "On the description of oval curves and those having a plurality of foci" \- accessed 2020-03-12 was presented to the Royal Society of Edinburgh by James Forbes, a professor of natural philosophy at the University of Edinburgh, because Maxwell was deemed too young to present the work himself. The work was not entirely original, since René Descartes had also examined the properties of such multifocal ellipses in the 17th century, but he had simplified their construction.
His son, inevitably, was called "Sau Doo Pei" – "Young Hunchback." Wagstaff had two sons – Don, killed in Naval service in the war, and Alex, killed while interned in Shanghai by the Japanese. Chou Yin Hsiang himself came to Hong Kong in 1935, and by 1977 was the proprietor of Jeh Hsing Metal Works – and still casting bronze for HSBC. Like the Shanghai lions, the Hong Kong lions became objects of veneration, and foci of the Bank's perceived excellent feng shui.
This plaque incorrectly credits the sculptor of the statue as being "Sir Bertram Macenell". The statue was actually sculpted by renowned artist, "Sir Bertram Mackennal" and is noted as being Mackennal's fiftieth sculpture. The strength of the central path as an axial feature has been diminished by the loss of its relationship with the stone remnants of the Holy Name Cathedral site. Thus the northern end of the central path lacks the strong foci provided elsewhere by the archway and the two statues.
The Institute grants the following degrees in sacred music: Bachelor (3 years), Licentiate (2 years) and a Doctorate. The degrees are offered with one of the following foci: Gregorian chant, composition, choral direction, musicology, pipe organ and pianoforte. Instruction in Italian is offered in harmony, counterpoint, fugue, composition, acoustics, music history and analysis, musicology, bibliography, research methods, ethno-musicology, editing of music, notation, Gregorian chant, liturgics, piano, pipe organ, score reading, continuo (figured bass), keyboard improvisation, choral conducting and Latin.
Occasionally, several adjacent glands will coalesce into a larger cauliflower-like cluster similar to sebaceous hyperplasia of the skin. In such an instance, it may be difficult to determine whether or not to diagnose the lesion as sebaceous hyperplasia or sebaceous adenoma. The distinction may be moot because both entities have the same treatment, although the adenoma has a greater growth potential. Sebaceous carcinoma of the oral cavity has been reported, presumably arising from Fordyce granules or hyperplastic foci of sebaceous glands.
The geometrical focus of a point seen by reflection or refraction is defined; and it is explained that the image of an object is the locus of the geometrical foci of every point on it. Barrow also worked out a few of the easier properties of thin lenses, and considerably simplified the Cartesian explanation of the rainbow. Barrow was the first to find the integral of the secant function in closed form, thereby proving a conjecture that was well- known at the time.
The lemniscate of Bernoulli and its two foci In algebraic geometry, a lemniscate is any of several figure-eight or -shaped curves. The word comes from the Latin "lēmniscātus" meaning "decorated with ribbons", from the Greek λημνίσκος meaning "ribbons",. or which alternatively may refer to the wool from which the ribbons were made. Curves that have been called a lemniscate include three quartic plane curves: the hippopede or lemniscate of Booth, the lemniscate of Bernoulli, and the lemniscate of Gerono.
His studies on motor response to faradic electrical stimulation of the cerebral cortex, internal capsule and spinal cord became classics of the field. These studies were later translated to his pioneering work in the neurosurgery for epilepsy. Horsley was also the first to use intraoperative electrical stimulation of the cortex for the localization of epileptic foci in humans, between 1884 and 1886, preceding Fedor Krause and Wilder Penfield. He was also a pioneer in the study of the functions of the thyroid gland.
See ), has two companion stars, pō tolo (the Digitaria star), and ęmmę ya tolo, (the female Sorghum star), respectively the first and second companions of Sirius A. Sirius, in the Dogon system, formed one of the foci for the orbit of a tiny star, the companionate Digitaria star. When Digitaria is closest to Sirius, that star brightens: when it is farthest from Sirius, it gives off a twinkling effect that suggests to the observer several stars. The orbit cycle takes 50 years.
The main features of this tumor is to comprise either ectodermal derivatives (neuroblasts and ganglion cells) or mesenchymal components mostly represented by plump, elongated cells in interlacing bundles often showing rhabdomyoblastic differentiation, including strap-like and racket-shaped cells (2-6). A myofibril-like structure and cross striations can be identified. Liposarcoma-like and chondroid foci can be an additional finding. Fibrosarcoma-like and fibrous histiocytoma-like areas can be observed as well as neurofibromatous and neuroblastic components with rosette formation.
Typical gross features include large size (mean diameter 11.3 cm), a mucoid texture, foci of necrosis, and prominent cyst formation.Argani, Pedram M.D.; Perlman, Elizabeth J. M.D.; Breslow, Norman E. Ph.D.; Browning, Nancy G. M.S.; Green, Daniel M. M.D.; D'Angio, Giulio J. M.D.; Beckwith, J. Bruce M.D., Clear Cell Sarcoma of the Kidney: A Review of 351 Cases From the National Wilms Tumor Study Group Pathology Center, American Journal of Surgical Pathology, Jan 2000, 24(1), p. 4, journals.lww.com. Accessed 2012-5-21.
During the Late Preclassic and Early Classic La Milpa was a small site located on a hilltop consisting of a few pyramids, one reservoir, and a few stelae. Excavations within Plaza A revealed a few monuments that date to this period indicating a growing population and therefore a need for increased space. The northern plaza was also occupied during this period. It was the foci of funerary monumental construction, which has led to the interpretation the dead were buried near the main population.
Relationship between Pythagorean triples and ellipses with integral linear eccentricity, and major and minor axes, for the first 3 Pythagorean triples With reference to the figure and the definition of the foci of an ellipse, F1 and F2, for any point P on the ellipse, F1P + PF2 is constant. As points A and B are both on the ellipse, F1A + AF2 = F1B + BF2. Due to symmetry, F1A + AF2 = F2A' + AF2 = AA' = 2 AC, and F1B + BF2 = 2 BF2. Hence, AC = BF2.
In 1988, the IFF had premises in Klagenfurt, Bregenz, Graz, St. Pölten, Stadtschlaining and Vienna. Ten years later, the IFF was serving more than 1,000 distance learning students via study centres in Klagenfurt, Bregenz and Vienna. In addition, the IFF developed new courses for Austria-wide teacher training programmes and began to establish its own research foci, centred on themes such as the environment, peace studies, social learning, regional development or technology and scientific research.Markus Arnold, Gert Dressel: iff – Geschichte einer interdisziplinären Institution.
Studies pointed out the permanence of infection in these foci, and the role played in this permanence by the presence of rodents showing a high resistance to infection. He came to the conclusion that it was necessary to look for a real plague reservoir not among sensitive species eradicated by infection, but among the semi-resistant species that survive. To prove this theory, WHO set up a research campaign associated with Institut Pasteur of Iran. In 1950, he became WHO' rabies committee expert.
Destiny is nearly completely new material offering three new character types: Arkus, Delve, and Wright, new descriptors and new foci. The book also emphasizes crafting along with community protection and development with these character types taking lead positions in such an endeavor. A major section on crafting mechanisms and a major section on communities are provided. The manner of running a community game can be described as treating the community as an NPC in the game with stats that the player characters enhance.
The school has eight "arts foci," or areas of study, including Dance, Writing And Publishing, Media Arts, Music, Vocal, Health Science and the Arts, Pre-Law And the Arts, Theatre, and Musical Theatre. The school's enrollment was 501 students in 2010.National Center for Education Statistics, Common Core data - Lincoln Park Performing Arts Charter School, 2010 Enrolled students included 87 pupils eligible for a federal free or reduced-price lunch. The school employed 26 teachers, yielding a student–teacher ratio of 20:1.
Ghising was appointed the mananging director of NEA on 14 September 2016 by a cabinet decision. He had been associated with NEA for over two decades prior to the appointment. At the time of the appointment, he was serving as the project chief of Rahughat Hydroelectricity Project, having been managing director of the Chilime Hydropower Company before that. Experienced in power trade and distribution, he said eliminating load shedding would be one of his main foci, in an interview following his appointment.
Tom Joyner is a writer and academic. Joyner received his B.A. in English from Rollins College and his M.A. and Ph.D. (both in Theater) from the University of Colorado Boulder. His research foci included 20th Century Irish drama, post-colonial theaters, and theaters of social justice. He has worked as a performer, dramaturg, educational outreach writer, and director with university, community, and professional theaters in Florida and Colorado and was part of the inaugural class for Naropa University's Actor-created Physical Theater program.
Bipolar coordinate system Bipolar coordinates are a two-dimensional orthogonal coordinate system based on the Apollonian circles.Eric W. Weisstein, Concise Encyclopedia of Mathematics CD-ROM, Bipolar Coordinates, CD-ROM edition 1.0, May 20, 1999 Confusingly, the same term is also sometimes used for two-center bipolar coordinates. There is also a third system, based on two poles (biangular coordinates). The term "bipolar" is further used on occasion to describe other curves having two singular points (foci), such as ellipses, hyperbolas, and Cassini ovals.
Gerstein does research in the field of bioinformatics. This involves applying a range of computational approaches to problems in molecular biology, including data mining and machine learning, molecular simulation, and database design. His research group has a number of foci including annotating the human genome,Gina Kolata, (Sept. 5, 2012) 'Bits of Mystery DNA, Far From Junk, Play Crucial Role,' NY Times personal genomics, cancer genomics, building tools in support of genome technologies (such as next-generation sequencing), analyzing molecular networks, and simulating macromolecular motions.
Natural springs were foci for healing cults: Sulis was prayed to as a healer at Aquae Sulis and the goddess Arnemetia was hailed as a healer at Aquae Arnemetiae. Nemausus, for example, was not only the Gallic name for the town of Nîmes but also that of its presiding spring-god. He had a set of three female counterparts, the Nemausicae. In the same region, the town of Glanum possessed a god called Glanis: an altar from a sacred spring is inscribed to Glanis and the Glanicae.
Rose's primary foci are Martin Heidegger, to whom she devotes three chapters, and Gilles Deleuze, Michel Foucault, and Jacques Derrida, to whom she devotes one chapter apiece. In addition, however, she scrutinises a few of the neo- Kantians (Emil Lask, Rudolf Stammler, and Hermann Cohen), Henri Bergson, and Ferdinand de Saussure and Claude Lévi-Strauss. Her central argument is that with the post-structuralists a "newly insinuated law [is] dissembled as a nihilistic break with knowledge and law, with tradition in general."Rose (1984). p. 7.
In everyday use, the term "circle" may be used interchangeably to refer to either the boundary of the figure, or to the whole figure including its interior; in strict technical usage, the circle is only the boundary and the whole figure is called a disc. A circle may also be defined as a special kind of ellipse in which the two foci are coincident and the eccentricity is 0, or the two-dimensional shape enclosing the most area per unit perimeter squared, using calculus of variations.
The initial step in field cancerization is associated with various molecular lesions such as acquired genetic mutations and epigenetic changes, occurring over a widespread, multi- focal "field". These initial molecular changes may subsequently progress to cytologically recognizable premalignant foci of dysplasia, and eventually to carcinoma in situ (CIS) or cancer. The image of a longitudinally opened colon resection on this page shows an area of a colon resection that likely has a field cancerization or field defect. It has one cancer and four premalignant polyps.
Planetary health aims to seek out further solutions to global human and environmental sustainability through collaboration and research across all sectors, including the economy, energy, agriculture, water, and health. Biodiversity loss, exposure to pollutants, climate change, and fuel consumption are all issues that threaten human and climate health alike, and are, as such, foci of the field. A number of researchers think that it is actually humanity's destruction of biodiversity and the invasion of wild landscapes that creates the conditions for new diseases such as Covid-19.
The neoplastic neuronal components are often clustered or irregularly oriented. Fibrovascular stroma confined to the neuronal component, perivascular lymphocytic infiltrates, and small foci of calcification are common, as is immunopositivity for synaptophysin, neuron-specific enolase, and chromogranin A. Elevated Ki-67 and p53 labeling index is associated with more aggressive tumor behavior in both children and adults with gangliogliomas. The rare occurrence of malignant transformation is confined to the glial cell population, and is characterized by increased cellularity and mitotic activity, endothelial proliferation, and necrosis.
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
The current control method of Chagas disease is to control the vector populations. The control strategies against this vector are very complex due to its capacity to infest natural and artificial environments presenting high levels of population density. Simple spraying methods are not as effective for T. brasiliensis as they are for other Triatoma species. Suggested methods of control currently include spraying more frequently with higher surveillance or to devise a strategy that attacks T. brasiliensis in sylvatic foci such as spraying palm trees.
Giant-cell carcinomas of the lung frequently show extensive necrosis and myxoid degeneration. A trend toward less vascularity and tissue density (with lower contrast enhancement on CT) has been noted toward the center of these lesions, especially in larger tumors, and even in tumors without a significant volume of gross necrosis. Grossly, the cut surfaces of these malignancies are often gray-white or tan, and frequently show myxoid, necrotic, and/or hemorrhagic foci. These sorts of areas often show low levels of contrast enhancement on CT scanning.
The first scholarly journal dedicated to Healthcare Engineering, Journal of Healthcare Engineering, was launched in 2010 by Dr. Ming-Chien Chyu, focusing on engineering involved in all aspects of healthcare delivery processes and systems. In the meantime, a number of companies with various foci have adopted “Healthcare Engineering” in their names. Healthcare Engineering was first defined in a white paper published in 2015 by Dr. Chyu and 40 co-authors who are active members of and contributors to the Healthcare Engineering community all over the world.
The flexure in the horizontal position of the tube was determined by two collimators – telescopes placed horizontally in the meridian, north and south of the transit circle, with their objective lenses towards it. These were pointed at one another (through holes in the tube of the telescope, or by removing the telescope from its mount) so that the crosshairs in their foci coincided. The collimators were often permanently mounted in these positions, with their objectives and eyepieces fixed to separate piers.Bond, Bond and Winlock (1876), p.
Gods also require statues of themselves as foci to enter the material world. Demons can, and often are, summoned from other planes of existence, which Novarians number in relation to their own (which to them is the Prime Plane). Novaria itself is a broad isthmus joining two continental masses to the north and the south. The northern continent consists primarily of the steppe country of Shven, with the pirate isles of Algarth off its western coast and the land of Hroth to the north.
Parish closes today form the foci for pardons, the annual Breton pilgrimage festivals, which can attract thousands of worshippers. The parish close of Guimiliau is situated at the upper end of the main village street, with the entrance dominating the village. The calvary or crucifix is the centre piece of the church yard, surrounded by a fine and complex retelling of the Passion in statuary. See Calvary at Guimiliau The church contains many fine examples of polychrome sculpture from the sixteenth century onwards, including several large retables.
Fort Ancient culture is divided into four distinct local variations known as foci (plural of focus). They are the Madisonville Focus, the Baum Focus, the Feurt Focus, and the Anderson Focus. Fort Ancient culture can be subdivided into at least 8 phases that fall into different time periods and different areas of southern Ohio and adjacent states. There was increasing similarity between Fort Ancient phases leading up to 1650 CE, characterized by the native artifacts and European trade goods found at the Madisonville site.
Recently the foci of research have expanded from the localization of brain area(s) for specific functions in the adult brain using a single technology, studies have been diverging in several different directions: exploring the interactions between different brain areas, using multiple technologies and approaches to understand brain functions, and using computational approaches. Advances in non-invasive functional neuroimaging and associated data analysis methods have also made it possible to use highly naturalistic stimuli and tasks such as feature films depicting social interactions in cognitive neuroscience studies.
This occurs mainly in severe infection following injection of viral particles and has not been reported from naturally infected P. vannamei. Shrimp that survive the acute stage enter a transitional stage. Shrimp in the transitional phase show randomly distributed, melanized (brownish/black) lesions within of the cuticle of the cephalothorax and tail region. These foci are the sites of acute lesions which have progressed onto subsequent stages of hemocytic inflammation,hemocytic – Biology Online cuticular epithelium regeneration and healing and which might be secondarily infected with bacteria.
By the Gauss–Lucas theorem, the root of the double derivative must be the average of the two foci, which is the center point of the ellipse and the centroid of the triangle. In the special case that the triangle is equilateral (as happens, for instance, for the polynomial ) the inscribed ellipse degenerates to a circle, and the derivative of has a double root at the center of the circle. Conversely, if the derivative has a double root, then the triangle must be equilateral .
Quetelet, Adolphe (1819) "Dissertatio mathematica inauguralis de quibusdam locis geometricis nec non de curva focali" (Inaugural mathematical dissertation on some geometric loci and also focal curves), doctoral thesis (University of Ghent ("Gand"), Belgium). (in Latin) The Dandelin spheres can be used to give elegant modern proofs of two classical theorems known to Apollonius of Perga. The first theorem is that a closed conic section (i.e. an ellipse) is the locus of points such that the sum of the distances to two fixed points (the foci) is constant.
Heath, Thomas. A History of Greek Mathematics, page 119 (focus-directrix property), page 542 (sum of distances to foci property) (Clarendon Press, 1921). Neither Dandelin nor Quetelet used the Dandelin spheres to prove the focus-directrix property. The first to do so may have been Pierce Morton in 1829,Numericana's Biographies: Morton, Pierce or perhaps Hugh Hamilton who remarked (in 1758) that a sphere touches the cone at a circle which defines a plane whose intersection with the plane of the conic section is a directrix.
The Fresnel zone was initially used to study the interference and diffraction of the light, which is later used to construct the wireless signal transmission model. Fresnel zone is a series of elliptical intervals whose foci are the positions of the sender and receiver. When a person is moving across different Fresnel zones, the signal path formed by the reflection of the human body changes, and if people move vertically through Fresnel zones, the change of signal will be periodical. In the paper,D.
Her habilitation was about the development of interest. In 2008 Anke Grotlüschen became Professor for Adult Education in Cultural and Social Contexts, before changing the position within the Institute for Education at the University of Hamburg, to become a professor for Lifelong Learning. The research foci of Anke Grotlüschen are educational interests, addressee research and interest research, literacy, learning resistance and E-Learning. In the area of higher education she focuses especially on public science and didactic as well as research of higher education.
The Bachman's bundle receives its blood supply from the sinoatrial nodal artery (right, left or both). Besides Bachmann's bundle, the other three conduction tracts that constitute the atrial conduction system are known as the anterior, middle, and posterior tracts, which run from the sinoatrial node to the atrioventricular node, converging in the region near the coronary sinus. Atrial automaticity foci are within the atrial conduction system. The concentration of converging conduction tracts near the coronary sinus results in considerable automaticity activity originating in that area.
FA-DLBCL is an incidental finding made by histological examination of tissues obtained at surgery conducted for reasons not related to FA-DLBCL. Microscopically, these tissues are composed of small foci of infiltrates composed of large lymphoid cells embedded in a background of fibrin or debris. Immunohistochemistry analyses reveals that the large neoplastic cells are B-cells by their expression of B-cell marker proteins (e.g. CD20, CD30, CD45, CD79a, PAX5, and MUM1) and are infected with the EBV by their expression of this virus's proteins, e.g.
Optics The telescope is a Ritchey–Chrétien f/11 which provides unvignetted 20 arcmin field of view at the main Cassegrain focus. In addition, 3 broken side foci are also provided, each with a field of view of 8 arcmin. The main mirror (M1) is a single segment fast f/1.5 mirror with a diameter of 3.4m, which makes INO340 one of the most compact telescopes for its size. M1 is a meniscus shape 18cm thick made of a Zerudor ceramic with a 700mm central hole.
In November 2008, the Conservancy started the Rare Breed Swine Initiative, which, in cooperation with other organizations, assists in training breeders and cultivating the rare breed pig market. The three main foci of the initiative are marketing breeding stock and products, conserving bloodlines and supporting breed associations. As of 2010, proposals were in place for the funding of a study of porcine genetics, including variability and relationships among breeds, with the aims of maintaining genetic variability among rare pig breeds and releasing a definition of heritage pork.
Kuskova was one of the founders and editors of the journal Nasha Zhizn (Our Life), which became the official organ of the KDP. She became associated with Father Gapon, an Orthodox priest and social reformer who led the unarmed demonstration on Bloody Sunday, January 9, 1905 (OS), that sparked the Revolution of 1905. Because of her association with Gapon, Kuskova was briefly arrested. Upon her release, she helped organise the Union of Unions, one of the principal foci of liberal opposition to the régime.
The International Summer University started as one of the Hessen International Summer Universities that have been designed to attract international students to Hessen.See the Hessen International Summer Universities (ISU) homepage for reference. Established in 2001, ISU offers short-term credit-bearing academic program featuring the strengths of University Kassel in the areas of Environmental Sciences and German Language & Culture studies. Apart from the academic components with specific foci, ISU is unique in its host-family program for students to experience first-hand German lifestyle.
The development of computational sociology involves such scholars as Nigel Gilbert, Klaus G. Troitzsch, Joshua M. Epstein, and others. The foci of methods in this field include social simulation and data-mining, both of which are sub-areas of computational sociology. Social simulation uses computers to create an artificial laboratory for the study of complex social systems; data-mining uses machine intelligence to search for non-trivial patterns of relations in large, complex, real-world databases. The emerging methods of socionics are a variant of computational sociology.
If one of the short (uncrossed) edges of an antiparallelogram linkage is fixed in place, and the remaining linkage moves freely, then the crossing point of the antiparallelogram traces out an ellipse that has the fixed edge's endpoints as its foci. The other moving short edge of the antiparallelogram has as its endpoints the foci of another moving ellipse, formed from the first one by reflection across a tangent line through the crossing point.. For both the parallelogram and antiparallelogram linkages, if one of the long (crossed) edges of the linkage is fixed as a base, the free joints move on equal circles, but in a parallelogram they move in the same direction with equal velocities while in the antiparallelogram they move in opposite directions with unequal velocities.. As James Watt discovered, if an antiparallelogram has its long side fixed in this way it forms a variant of Watt's linkage, and the midpoint of the unfixed long edge will trace out a lemniscate or figure eight curve. For the antiparallelogram formed by the sides and diagonals of a square, it is the lemniscate of Bernoulli., pp. 58–59.
Neuroscience Stanley Institute for Cognitive Genomics employs deep sequencing and other tools to study genetics underlying schizophrenia, bipolar disorder, and major depression. Swartz Center for the Neural Mechanisms of Cognition studies cognition in the normal brain as a baseline for understanding dysfunction in psychiatric and neurodegenerative disorders. Other research foci: autism genetics; mapping of the mammalian brain; neural correlates of decision making. Plant biology Plant genome sequencing; epigenetics and stem cell fate; stem cell signaling; plant-environment interactions; using genetic insights to increase yield of staple crops, e.g.
Construction grammar is a similar foci of cognitive approaches to grammar. While cognitive grammar emphasizes the study of the cognitive principles that give rise to linguistic organization, construction grammar aims to provide a more descriptively and formally detailed account of the linguistic units that comprise a particular language. Langacker first explicates the system of cognitive grammar in his seminal, two-volume work Foundations of Cognitive Grammar. Volume one is titled "Theoretical Prerequisites", and it explores Langacker's hypothesis that grammar may be deconstructed into patterns that come together in order to represent concepts.
Plates are subsequently probed with fluorescently labeled antibodies against a viral antigen, and fluorescence microscopy is used to count and quantify the number of foci. The FFA method typically yields results in less time than plaque or fifty-percent-tissue-culture-infective-dose (TCID50) assays, but it can be more expensive in terms of required reagents and equipment. Assay completion time is also dependent on the size of area that the user is counting. A larger area will require more time but can provide a more accurate representation of the sample.
The Military History of Russian Troubles of the Early 17th Century. Moscow: Quadriga, 2014 – Page 134 The infantry rushed into the resulting gaps, which soon recaptured the Chudintsev Gates from the defenders and opened them to Delagardi's strong cavalry. From the towers of Okolny City, the Russians methodically fired on the Swedes, however, after the cavalry attack, which began to quickly take over the streets, the fate of the city, despite the stubborn foci of resistance, was a foregone conclusion. A fire and general panic began in the city.
The 3D trap itself generally consists of two hyperbolic metal electrodes with their foci facing each other and a hyperbolic ring electrode halfway between the other two electrodes. The ions are trapped in the space between these three electrodes by AC (oscillating) and DC (static) electric fields. The AC radio frequency voltage oscillates between the two hyperbolic metal end cap electrodes if ion excitation is desired; the driving AC voltage is applied to the ring electrode. The ions are first pulled up and down axially while being pushed in radially.
The classical theory developed in the early 70's anticipated that metastasis is due to genetically determined subpopulations in primary tumours. The genetic variance between metastatic foci is significant for only particular locus and within specific cell populations or only one-cell population shows differences and some loci are divergent only in one cell subpopulation. This explains the concept of tumour heterogeneity and the order of genetic events during tumor evolution. Many of the genes driving the growth at primary site can determine the dissemination and colonization at the ectopic site.
Senescent cells can undergo conversion to an immunogenic phenotype that enables them to be eliminated by the immune system. This phenotype consists of a pro-inflammatory secretome, the up-regulation of immune ligands, a pro-survival response, promiscuous gene expression (pGE) and stain positive for senescence-associated β-galactosidase activity. The nucleus of senescent cells is characterized by senescence-associated heterochromatin foci (SAHF) and DNA segments with chromatin alterations reinforcing senescence (DNA-SCARS). Senescent cells affect tumour suppression, wound healing and possibly embryonic/placental development and a pathological role in age- related diseases.
Rats were fed aflatoxin and varying amounts of protein (between 5% and 20% of their diet). A low-protein diet greatly reduced tumor initiation by several mechanisms; for example, enzyme activity dropped and fewer toxins binded to DNA. In the promotion phase, the development of foci was "almost entirely dependent on how much protein was consumed, regardless of how much aflatoxin was consumed." They developed if the protein content exceeded the amount (12%) that their bodies required to grow, and focal growth could be switched on or off by varying the protein.
The Mica Creek area was one of the foci of the Big Bend Gold Rush of the 1860s. The village of Mica Creek reached its peak population of approximately 4000 people around 1973, at the time of the opening of the Mica Dam. At that time there were quite a number of amenities including a school, church, ski lodge, community center, outdoor swimming pool, police station, fire hall, grocery store and post office. As the village reduced in population, these were gradually shut down; the high school closed its doors in 1978.
Active RNA Pol II transcription holoenzymes can be clustered in the nucleus, in discrete sites called transcription factories. There are ~8,000 such factories in the nucleoplasm of a HeLa cell, but only 100–300 RNAP II foci per nucleus in erythroid cells, as in many other tissue types. The number of transcription factories in tissues is far more restricted than indicated by previous estimates from cultured cells. As an active transcription unit is usually associated with only one Pol II holoenzyme, a polymerase II factory may contain on average ~8 holoenzymes.
AGK expression has also been correlated with certain cancer phenotypes. AGK expression, in coordination with AGX, was not detected in non-neoplastic epithelia, while both were weakly expressed in the majority of high-grade intra-epithelial neoplasia (HG-PIN). Expressions of both enzymes were significantly correlated with primary Gleason grade of cancer foci and capsular invasion. Overexpression of AGK sustains constitutive JAK2/STAT3 activation, consequently promoting the cancer stem cell population and augmenting the tumorigenicity of esophageal squamous cell carcinoma (ESCC) cells both in vivo and in vitro.
Even during the initial episode, spirochaetes can only be seen 70% of the time. Especially in resource-poor areas, people continue to be afflicted by undiagnosed febrile illnesses, which pose a significant health burden. However, the ecology, pathogenesis, and distribution of B. turicatae remains understudied, and regions of endemicity not previously known to exist continue to be identified. Because relapsing fever has such nonspecific clinical manifestations, the disease is likely underreported, thus improved diagnostic tools for relapsing fever spirochaetes are needed to better identify the endemic foci and to ensure proper treatment.
A limitation in defining the distribution of B. turicatae has been the absence of diagnostic antigens specific for the species. A spirochaete antigen designated the Borrelia immunogenic protein A (BipA) has been identified in B. turicatae. As antibody responses generated against recombinant BipA appear to be unique to infections caused by B. turicatae, these immune responses generated against BipA suggest that it may be a species-specific antigen that could be used to identify additional vertebrate hosts, define endemic foci for B. turicatae, and increase the awareness of the disease to improve healthcare.
The cult had twin foci: his tomb, in the apse, directly behind the high altar of the cathedral; and more particularly his skull, kept in a special Head Chapel, above the south aisle. The transmission of the relics after the Reformation was tortuous. At the dissolution of the Shrine on the instructions of King Henry VIII in about 1538, Prebendary Arthur Dudley of Lichfield Cathedral removed and retained some relics, probably a travelling set. These were eventually passed to his nieces, Bridget and Katherine Dudley, of Russells Hall.
Young mites move about on the skin and molt into a "nymphal" stage, hosting Bacillus anthracis in their digestive tract. They act as a vector that carries and transmits anthrax to their hosts causing an infection, which often results in death because the immune system was weakened by scabies before. The high host specificity of the mites is held responsible for the fact that mostly even- toed ungulates struggled with these consequences. In late 1950s the last foci of infection were reported in semi-domesticated reindeers after which no greater incidences were observed.
The Nahuelbuta Range or Cordillera de Nahuelbuta () is a mountain range in Bio-Bio and Araucania Region, southern Chile. It is located along the Pacific coast and forms part of the larger Chilean Coast Range. The name of the range derives from the Mapudungun words nahuel (jaguar) and futa (big) Historically Cordillera de Nahuelbuta and its surrounding valleys were the foci of the Arauco War. The Spanish designs for this region was to exploit the placer deposits of gold around the range using unfree Mapuche labour from the densely populated valleys.
Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome. It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) double strand DNA break repair complex. This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs).
The acronym chILD is used for this group of diseases and is derived from the English name, Children's Interstitial Lung Diseases – chILD. Prolonged ILD may result in pulmonary fibrosis, but this is not always the case. Idiopathic pulmonary fibrosis is interstitial lung disease for which no obvious cause can be identified (idiopathic) and is associated with typical findings both radiographic (basal and pleural-based fibrosis with honeycombing) and pathologic (temporally and spatially heterogeneous fibrosis, histopathologic honeycombing, and fibroblastic foci). In 2015, interstitial lung disease, together with pulmonary sarcoidosis, affected 1.9 million people.
The idea to establish a center for media, religion and culture was introduced by Paul S. Voakes in 2003 when the dean saw Hoover’s success in attracting support from the Lilly Endowment, Inc to conduct research on media and religion. What started as a research collaboration between Hoover, his graduate students and his colleagues in Europe began to develop into something bigger. In November 2004 Hoover with the assistance of Lynn Schofield Clark wrote a proposal for the establishment of the center. They identified project areas that later became the center's foci.
By 2015, the disease had infected up to a million olive trees in Apulia and Xylella fastidiosa had reached Corsica, By October 2015, it had reached Mainland France, near Nice, in Provence-Alpes-Côte d'Azur, affecting the myrtle-leaf milkwort (Polygala myrtifolia). This is the subspecies X. fastidiosa subsp. multiplex which is considered to be a genetic variant of the bacterium, different to that found in Italy. On 18 August 2016 in Corsica, 279 foci of the infection have been detected, concentrated mostly in the south and the west of the island.
Reflexivity: Definitions and discriminations. Semiotica. 1980 30:1-2, 1-14 One important origin for this approach is Roman Jakobson in his studies of deixis and the poetic function in language, but the work of Mikhail Bakhtin on carnival has also been important. Within anthropology, Gregory Bateson developed ideas about meta-messages (subtext) as part of communication, while Clifford Geertz's studies of ritual events such as the Balinese cock-fight point to their role as foci for public reflection on the social order. Studies of play and tricksters further expanded ideas about reflexive cultural practices.
Focal proliferative nephritis is a type of glomerulonephritis seen in 20% to 35% of cases of lupus nephritis, classified as type III. As the name suggests, lesions are seen in less than half of the glomeruli. Typically, one or two foci within an otherwise normal glomerulus show swelling and proliferation of endothelial and mesangial cells, infiltration by neutrophils, and/or fibrinoid deposits with capillary thrombi. Focal glomerulonephritis is usually associated with only mild microscopic hematuria and proteinuria; a transition to a more diffuse form of renal involvement is associated with more severe disease.
BRCA1 directly binds to DNA, with higher affinity for branched DNA structures. This ability to bind to DNA contributes to its ability to inhibit the nuclease activity of the MRN complex as well as the nuclease activity of Mre11 alone. This may explain a role for BRCA1 to promote lower fidelity DNA repair by non-homologous end joining (NHEJ). BRCA1 also colocalizes with γ-H2AX (histone H2AX phosphorylated on serine-139) in DNA double-strand break repair foci, indicating it may play a role in recruiting repair factors.
In England, dark earth covers many areas that were built up in the Roman period, especially Londinium. In some cases, it may represent open spaces on the edge of urban centres, but can also be found in more rural settings in and around foci of settlement. In the example of London, deposits underlying the ancient city's dark earth are often dated to between the 2nd to 5th century, the middle and later Roman period. Overlying deposits are frequently dated to the 9th century when Saxon London was repopulated and began to expand.
" Entertainment Weekly said it "lacks a center. It's an exhausted sprawl with multiple story foci, none of them terribly compelling," concluding, "Dahl does vividly re- create that least heralded burden of war: the boredom." Steven Rea of The Philadelphia Inquirer wrote, "The Great Raid, which documents the largest rescue mission in U.S. military history (and ends with archival footage of many of the real soldiers portrayed in the film), lacks the visceral sweep of Saving Private Ryan. But Spielberg's story, for all its gut-wrenching intensity, was a fiction.
Food-borne trematodes are currently the most important parasitic infections in Korea and approximately 240,000 Koreans are believed to be currently infected. Of the 240,000 estimated to be infected, 120,000 are caused by M. yokagawai, 20,000 by M. takahashii, and 100,000 by M. miyatai. The national rate of infections among randomly selected people was 1.2% in 1981, 1.0% in 1986, and down to 0.5% in 2004. M. yokagawai infections are found mostly around the large and small streams where sweetfish live and have been identified as endemic foci.
Among his works are: Il fosso Ghiaia a Ravenna; Sulle sponde del Nera; Intorno alla Pineta; The Adriatic Beach in Pesaro; and Albacina. In 1870 at Parma, he exhibited a Vallala di Poschiavo dal monte Cavagna. In 1877 at Naples, he exhibited a Fosso Ghiaia nella Pineta di Ravenna and a Paesaggio. Among his works exhibited in Turin, Milan, Rome and Bologna, were: In riva all' Adriatico; Sulle colline; Marina di Pesaro a levante; Marina di Pesaro verso Cattolica; Le foci di Piobbico; Stazione di Foligno; and Appennino Metaurense.
Significant progress has been accomplished by CEF in characterizing several signalling pathways and their regulation by PTMs including ubiquitylation, phosphorylation and acetylation. A particular focus of research in CEF has been on protein quality control mechanisms that are the basis for the autophagic and the ubiquitin/proteasomal pathways, the two cellular systems used to degrade faulty or superfluous proteins, complexes and organelles. Additional foci of CEF research were genetic quality control in oocytes and epithelial stem cells by the p53 protein and the regulation of and by kinases.
Due to a peculiarity of Virginia's original charter, its boundary with Maryland and Washington, D.C. does not extend past the low-water mark of the south shore of the Potomac River (unlike many boundaries that split a river down the middle). The southern border is defined as the 36° 30′ parallel north, though surveyor error led to deviations of as much as three arcminutes. The state agencies whose primary foci are on the natural environment of Virginia are the Department of Conservation and Recreation (DCR), and the Department of Environmental Quality (DEQ).
The twin 10-meter telescopes at W. M. Keck Observatory in Hawaii and the 8.2-meter Subaru Telescope sited next to them support an array of specialized instruments on Nasmyth platforms, with a similar design being used for the future Thirty Meter Telescope. The 2.4-meter Automated Planet Finder telescope at Lick Observatory in California supports the use of two Nasmyth foci. The Sierra Nevada Observatory (OSN) in Spain has two Nasmyth telescopes, including a 1.5-meter diameter aperture one. The SOFIA airborne telescope also uses this design.
An n-ellipse is the set of points all having the same sum of distances to n foci. (The n=2 case is the conventional ellipse.) The concept of a focus can be generalized to arbitrary algebraic curves. Let C be a curve of class m and let I and J denote the circular points at infinity. Draw the m tangents to C through each of I and J. There are two sets of m lines which will have m2 points of intersection, with exceptions in some cases due to singularities, etc.
Most importantly, Kin have the ability to steal the life force of humans in order to survive, through a process called Drain. The Kin are divided into a number of groups, called Factions, who vary in their attitude toward humans and their willingness to be discreet about their activities. Players are generally encouraged to play Kin who prefer to defend Herd as well as Kin society, and to not kill mercilessly or wantonly. The nightlife of Kin in New York City is one of the primary foci of the game.
5mC marks are placed on genomic DNA via DNA methyltransferases (DNMTs). There are 5 DNMTs in humans: DNMT1, DNMT2, DNMT3A, DNMT3B, and DNMT3L, and in algae and fungi 3 more are present (DNMT4, DNMT5, and DNMT6). DNMT1 contains the replication foci targeting sequence (RFTS) and the CXXC domain which catalyze the addition of 5mC marks. RFTS directs DNMT1 to loci of DNA replication to assist in the maintenance of 5mC on daughter strands during DNA replication, whereas CXXC contains a zinc finger domain for de novo addition of methylation to the DNA.
In August 2016 a group based in Glasgow, Scotland launched the Save Falls of Clyde – International (FOCI) Campaign, with a view to have her returned to Scotland where she was originally built. Initially, They answered a call for help from the charity known as the ‘Friends of the Falls of Clyde’ (FFOC) who owned and wanted to save the FOC from being scuttled by the Hawaiian Harbours Department. They quickly put together a plan to get her back to Scotland attempting to work with the Hawaiian Harbours department and building and executing a plan.
The Normanton "linear" cemetery emerged along the main ridge, with three foci marking the landscape in a relatively straight line. Even though it is very likely that each focus was previously a Beaker grave, there is a clear tendency towards building sizeable mounds. Grave clustering seems to be present to some extent, especially in one of the Beaker burials and in the Bush Barrow. Although most of the barrows were constructed by the end of the Early Bronze Age, a significant change appears in the middle of the Bronze Age.
Given the equation : 9x^2 + 25y^2 + 18x - 100y - 116 = 0 , by using a translation of axes, determine whether the locus of the equation is a parabola, ellipse, or hyperbola. Determine foci (or focus), vertices (or vertex), and eccentricity. Solution: To complete the square in x and y, write the equation in the form : 9(x^2 + 2x \qquad ) + 25(y^2 - 4y \qquad ) = 116 . Complete the squares and obtain : 9(x^2 + 2x + 1) + 25(y^2 - 4y + 4) = 116 + 9 + 100 : \Leftrightarrow 9(x + 1)^2 + 25(y - 2)^2 = 225 .
The victory of this battle marked the end of the War of Reform and Conservative caused the disintegration of the army. On 25 December at Christmas 1860, General Gonzalez Ortega made his triumphant return to Mexico City in front of 30,000 troops input, thus ending the war with the triumph of liberal side in the War of Reform. On January 5 President Benito Juarez entered the capital from Veracruz marking the official end of hostilities. However, although they were defeated, the Marquez and Tomas Mejia Cobos general continued to resist in some conservative foci.
Marketisation and existing Market Theory In considering the applicability of the existing literature on contingency theory and perspectives on competitive advantage to the marketised social care sector in the UK, Dearnaley identified a number of areas in each that restrict its value in analysing and responding to the new market environment: the retrospective nature of theories of competitive advantage and foci on differentiation and cost leadership make these inappropriate for this new marketplace; the intangibility of competitive advantage, and particularly sustainable competitive advantage; the relative inflexibility of classical contingency theory.
These foci are negative for TSV by in situ hybridization (ISH) using a TSV-specific cDNA probe. Histologically, these shrimp present focal active acute lesions and the onset of lymphoid organ spheroids (LOSs) development. By ISH with TSV-specific probes, a diffuse positive signal can be observed within the walls of the lymphoid organ of normal appearance with or without focal probe signals within developing LOSs. These shrimp will be lethargic and anorexic, possibly because of the redirection of their energy and metabolic resources toward wound repair and recovery.
Ownership rights focuses on the access women have to property. Whether or not women are allowed to own land and or houses and their access to bank loans and credit are foci under this sub index. Son preference, also sometimes referred to as missing women, consists of variables looking at gender bias in mortality including human trafficking and missing person reports. The index is an unweighted average of these 5 sub-indices and measures on a scale from 0 to 1 the level of gender inequality in social institutions (higher levels indicate greater inequality).
A cubic polynomial has three zeroes in the complex number plane, which in general form a triangle, and the Gauss–Lucas theorem states that the roots of its derivative lie within this triangle. Marden's theorem states their location within this triangle more precisely: :Suppose the zeroes , , and of a third-degree polynomial are non-collinear. There is a unique ellipse inscribed in the triangle with vertices , , and tangent to the sides at their midpoints: the Steiner inellipse. The foci of that ellipse are the zeroes of the derivative .
Functional attitude theory (FAT) suggests that beliefs and attitudes are influential to various psychological functions. Attitudes can be influential on many processes such as being utilitarian (useful), social, relating to values, or a reduction of cognitive dissonance. They can be beneficial and help people interact with the world. In the late 1950s when psychoanalysis and behaviorism reigned supreme as the foci of psychological studies, Smith, Bruner, and White (1956) and Katz (1960) separately and independently developed typologies of human attitudes in relation to the functions to which they believed the attitudes served.
Amyloidosis, dystrophic calcification Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, including as a consequence of medical device implantation. Dystrophic calcification can occur even if the amount of calcium in the blood is not elevated (a systemic mineral imbalance would elevate calcium levels in the blood and all tissues) and cause metastatic calcification. Basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell.
Why settle for lesser materials when you can have the best? Despite his other foci, Hutchins does not entirely shun the laboratory world; he believes, however, that some such things are best learned through discovery once a student has been graduated to the outside world. In Utopia, initial schooling is followed by college, which continues the study of a highly prescribed curriculum. Here, however, the focus shifts from learning the techniques of communication to exploring some of man's principal concepts of the world and the leading ideas that have propelled mankind.
APP for mathematics consists of 208 areas of Assessment Focus (AF) across levels 1 to 8, giving between 20 and 25 areas for a pupil to complete per level. The optional National Curriculum tests have tended to test a narrow part of the National Curriculum whereas APP gives a much broader picture. The Assessment Foci can be quite specific, such as "plot graphs of quadratic and cubic functions". Some areas are less traditional and have come as something of a surprise to those who have worked with them.
DNA replication is an energy consuming process and hence in bacteria the process only occurs at a specific checkpoint in the cell cycle. The binding of SeqA protein to hemimethylated GATC sequences is important in the negative modulation of chromosomal initiation at oriC, and in the formation of SeqA foci necessary for Escherichia coli chromosome segregation. SeqA tetramers are able to aggregate or multimerize in a reversible, concentration-dependent manner. Apart from its function in the control of DNA replication, SeqA may also be a specific transcription factor.
The Dungeness mirrors, known colloquially as the "listening ears", consist of three large concrete reflectors built in the 1920s-1930s. Their experimental nature can be discerned by the different shapes of each of the three reflectors: one is a long curved wall about high by long, while the other two are dish-shaped constructions approximately in diameter. Microphones placed at the foci of the reflectors enabled a listener to detect the sound of aircraft far out over the English Channel. The reflectors are not parabolic, but are actually spherical mirrors.
The first settlers in Koxinga and Qing periods brought with them images or incense ashes from mainland temples, installed them in homes or temporary thatched huts, and later in proper temples, as economic circumstances permitted to build them. Prominent temples became the foci of religious, political and social life, often eclipsing Qing officials and state-sponsored temples in their influence. There is little evidence that the doctrinal and initiatory religions of Buddhism and Taoism were active during this period. Taiwan, as a frontier land, was not attractive for Buddhist and Taoist religious leaders.
Students and faculty in the Department of Communication study the nature and effects of communication on individuals, social groups, and society, including the ways in which communication is practiced in everyday life and the choices about communication that affect individuals and their situation. This program was founded as an undergraduate program in 1971. Organizational communication, mediated communication, language and social interaction, and interpersonal communication are primary areas of faculty research with change, collaboration, culture, health, gender, globalization, identity, leadership, persuasion, policy, and relationship development prominent problem-centered research foci across areas.
Ultimately, neuroscientists would like to understand every aspect of the nervous system, including how it works, how it develops, how it malfunctions, and how it can be altered or repaired. Analysis of the nervous system is therefore performed at multiple levels, ranging from the molecular and cellular levels to the systems and cognitive levels. The specific topics that form the main foci of research change over time, driven by an ever-expanding base of knowledge and the availability of increasingly sophisticated technical methods. Improvements in technology have been the primary drivers of progress.
A field defect is illustrated in the photo and diagram shown of a colon segment having a colon cancer and four small polyps within the same area as well. As pointed out by Rubin, "The vast majority of studies in cancer research has been done on well-defined tumors in vivo, or on discrete neoplastic foci in vitro. Yet there is evidence that more than 80% of the somatic mutations found in mutator phenotype human colorectal tumors occur before the onset of terminal clonal expansion." Similarly, Vogelstein et al.
The image at the transverse focus is a short line, oriented in the direction of the sagittal plane; images of circles centered on the optic axis, or lines tangential to such circles, will be sharp in this plane. The image at the sagittal focus is a short line, oriented in the tangential direction; images of spokes radiating from the center are sharp at this focus. In between these two foci, a round but "blurry" image is formed. This is called the medial focus or circle of least confusion.
The Aschoff nodules are foci of T lymphocytes, occasional plasma cells, and activated macrophages (Anitschkow cells) pathognomonic of rheumatic fever. These macrophages have abundant cytoplasm and central round nuclei in which chromatin condenses into a central, slender, wavy ribbon, reason why they are sometimes called "caterpillar cells". They are especially found in the vicinity of small blood vessels in the myocardium and endocardium and occasionally in the pericardium, and also the adventitia of the proximal part of the aorta. Lesions similar to the Aschoff nodules may also be found in extra-cardiac tissues.
Multifocal multiphoton microscopy is a microscopy technique for generating 3D images, which uses a laser beam, separated by an array of microlenses into a number of beamlets, focused on the sample. The multiple signals are imaged onto a CCD camera in the same way as in a conventional microscope. The image rate is determined by the camera frame rate, depending on the readout rate and the number of pixels and may range well above 30 images/s. By exploiting specific properties of pulsed-mode multiphoton excitation the conflict between the density of the foci, i.e.
It might appear that Cuny's career evolved from an initial focus on natural disasters, displaced persons emergencies and technical issues related to shelter and that it later turned to more complex emergencies, especially those related to conflict and the protection of civilians. In reality, his interests and observations covered all aspects simultaneously but the specific clients and disasters he was hired to address required narrower foci. Even though Cuny's career was not segmented by disaster type, the following subsections group general categories of emergencies as examples of some of his most important accomplishments.
In the process of morphogenesis focuses PVL pass through three stages: 1) necrosis, 2) resorption, and 3) the formation gliosis scars or cysts. Cysts occur when large and confluent focuses of PVL, with mixed necrosis (kollikvacia in the center and coagulation rim at the periphery). Around the foci is generally defined area of other lesions of the brain white matter - the death of prooligodendrocytes, proliferation mikrogliocytes and astrocytes, swelling, bleeding, loss of capillaries, and others (the so-called "diffuse component PVL"). However, diffuse lesions without necrosis are not PVL.
Brain scanning techniques such as functional magnetic resonance imaging have been used to investigate brain regions that seem to be involved in producing the human experience of love. In 2000, a study led by Semir Zeki and Andreas Bartels of University College London concluded that at least two areas of the brain become more active when in love. These were foci in the media insula, which the brain associates with instinct, and part of the anterior cingulate cortex, which is associated with feelings of euphoria. Ortigue et al.
To the naked eye, this has the texture of soft, white cheese and is termed caseous necrosis. If TB bacteria gain entry to the blood stream from an area of damaged tissue, they can spread throughout the body and set up many foci of infection, all appearing as tiny, white tubercles in the tissues. This severe form of TB disease, most common in young children and those with HIV, is called miliary tuberculosis. People with this disseminated TB have a high fatality rate even with treatment (about 30%).
"An Elementary Proof of Marden's Theorem", 2008, American Mathematical Monthly 115, 330–338. This ellipse has the greatest area of any ellipse tangent to all three sides of the triangle. The Mandart inellipse of a triangle is the ellipse inscribed within the triangle tangent to its sides at the contact points of its excircles. For any ellipse inscribed in a triangle ABC, let the foci be P and Q. ThenAllaire, Patricia R.; Zhou, Junmin; and Yao, Haishen, "Proving a nineteenth century ellipse identity", Mathematical Gazette 96, March 2012, 161–165.
B. malayi infects 13 million people in south and southeast Asia and is responsible for nearly 10% of the world's total cases of lymphatic filariasis. B. malayi infection is endemic or potentially endemic in 16 countries, where it is most common in southern China and India, but it also occurs in Indonesia, Thailand, Vietnam, Malaysia, the Philippines, and South Korea. The distribution of B. malayi overlaps with W. bancrofti in these regions, but does not coexist with B. timori. Regional foci of endemicity are determined in part by the mosquito vectors (see Transmission).
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex known as shelterin, that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Alternatively spliced transcript variants have been described. The absence of POT1 in mouse embryonic fibroblasts and chicken cells leads to a detrimental DNA damage response on telomeres resulting in telomere dysfunction-induced foci (TIFs).
If infected into the yolk sac, the embryo will succumb to death accompanied by hemorrhaging of the embryos and cause the foci on the liver to appear yellowish-green. There are several primary chicken cell cultures/areas that are susceptible to avian reoviruses, which include the lungs, liver, kidney, and fibroblasts of the chick embryo. Of the following susceptible areas, liver cells from the chick embryo have been found to be the most sensitive for primary isolation from clinical material. Typically, the CPE effect of avian reoviruses is the production of syncytia.
They noted that, "Focal infection is a splendid example of a plausible medical theory which is in danger of being converted by its enthusiastic supporters into the status of an accepted fact." Newly a critic, Cecil alleged that foci were "anything readily accessible to surgery". In 1939, E W Fish implanted bacteria into guinea pigs' jaws and reported that four zones develop. The first zone was the zone of infection, whereas the other three zones—surrounding the zone of infection—revealed immune cells or other host cells but no bacteria.
DNA/RNA-binding protein KIN17 is a protein that in humans is encoded by the KIN gene. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.
A bifocal reflectarray has two principle foci, so can focus wavefronts to or from two feeding antennas simultaneously. A dual reflectarray consists of two stages of reflection, in which the beam is first focused by one reflectarray, then by another. The phase distribution on each reflectarray must be carefully calculated to ensure that the phase derivatives are consistent with the angle of incidence of the rays The ratio of the sizes and positions of these reflectarrays can be used to achieve quasi-optical magnification (narrowing of the beam).
Minh spent a decade studying leprosy and vitiligo in various parts of Russia. Having explored the foci of leprosy during a special expedition to Persia, Central Asia and the Caucasus, he gave a description of the clinic and epidemiology of leprosy, and proved that leprosy is an infectious disease. He likewise visited the Astrakhan steppes, the Kuban region, and as for as a trip to Egypt and the Levant, where he collected extensive material on the history of leprosy since ancient times. Minh maintained that the biblical tzaraath is synonymous with the modern term vitiligo.
The International Network on Higher Education in Africa (INHEA) has been a special initiative in recent years. INHEA focuses on African higher education issues and provides information and analysis from many sources. Additional Center foci include the Corruption Monitor, which highlights incidents of academic corruption in its many forms and seeks to provide analysis of trends. In 2010, the Center, in collaboration with the National Research University Higher School of Economics on Moscow, Russia, engaged in a joint research project on academic salaries, remuneration and contracts across 28 countries.
Trilinear equation: [cyclic sum (cos A)x(b2y2 − c2z2)] = 0 Barycentric equation: [cyclic sum (b2 \+ c2 − a2)x(y2 − z2)] = 0 The Lucas cubic is the locus of a point X such that the cevian triangle of X is the pedal triangle of some point; the point lies on the Darboux cubic. The Lucas cubic passes through the centroid, orthocenter, Gergonne point, Nagel point, de Longchamps point, other triangle centers, the vertices of the anticomplementary triangle, and the foci of the Steiner circumellipse. For graphics and properties, see K007 at Cubics in the Triangle Plane.
The institution identifies itself as a reform university, due to its most famous alumnus Martin Luther, the instigator of the Reformation, who studied there from 1501 to 1505. Today, the main foci centre on multidisciplinarity, internationality, and mentoring. The university is home to the Max Weber Center for Advanced Cultural and Social Studies, the Gotha Research Center for Cultural and Social Scientific Studies, and the Willy Brandt School of Public Policy. The Gotha Research Library, which has one of Germany's largest collections of early modern manuscripts, is part of the university.
This eliminates the need for a secondary, and instead the observing instruments are placed at the prime focus. For secondary roles, two Nasmyth foci can be used, with an effective f/30. The long focal length and lack of a secondary placed in front of the prime focus makes for a long telescope overall; BTA's main tube is 26 m long. This would have required a massive equatorial mount, so BTA instead uses an altazimuth mount with computer controls to keep the motion of the sky still in the view.
In Canada, an analogous experiment called Mincome took place in Winnipeg and Dauphin, Manitoba, between 1974 and 1979. Importantly, the city of Dauphin served as a saturation site, since all 10,000 community members were eligible to participate (the elderly and disabled were exempt from the four American NIT experiments); four foci of Mincome were an economic arm (examining labour response), a sociologic research division (examining the family formation and community cohesion), an administrative programme, and a statistical division.Forget, E. (2008). The town with no poverty: A history of the North American Guaranteed Annual Income.
Hudson's research foci include foreign policy analysis, national security policy, social science methodology, and gender in International Relations. She has also published Mormon-related writings, particularly on the topic of Mormon doctrine concerning women. Hudson has written or edited several books, including Foreign Policy Analysis: Classical and Contemporary Theory (Boulder, Colorado: Rowman and Littlefield, 2007, 2013, 2019), Culture and Foreign Policy, Artificial Intelligence and International Politics as well as Bare Branches: Security Implications of Asia's Surplus Male Populations (MIT Press, 2004). The last was with Andrea Den Boer.
Apart from the academic components with specific foci, IWU is unique in its host-family program for students to experience first-hand German lifestyle. The University's long-standing partnerships with industries in the region and experiences in university-industry knowledge transfer also bring additional benefit to IWU students by giving them opportunities to witness the application of academic knowledge in industrial settings. Since its inception, IWU has received on average some 50 international students each year. The number of students is on the rise with its growing popularity among partnering universities.
In normal repair, the hyperplastic type II AECs die and the remaining cells spread and undergo a differentiation process to become type I AECs. Under pathologic conditions and in the presence of transforming growth factor beta (TGF-β), fibroblasts accumulate in these areas of damage and differentiate into myofibroblasts that secrete collagen and other proteins. In the past, it was thought that inflammation was the first event in initiating lung tissue scarring. Later findings showed that the development of fibroblastic foci precedes the accumulation of inflammatory cells and the consequent deposition of collagen.
Early Scooby-Doo merchandise included a 1973 Milton Bradley board game, decorated lunch boxes, iron-on transfers, coloring books, story books, records, underwear, and other such goods."Scooby-Doo according ot Wingnut: Collectibles". Wingnuttoons.com.Retrieved on August 12, 2006. Contains an extensive illustrated list of Scooby-Doo-related merchandise, from the 1970s to the present. When Scrappy-Doo was introduced to the series in 1979, he, Scooby, and Shaggy became the foci of much of the merchandising, including a 1983 Milton-Bradley Scooby-Doo and Scrappy-Doo board game.
The Ontario Moderate Party is a minor centrist political party in Ontario, Canada founded in 2014. The party's stated foci are improving manufacturing and industry in Ontario, reducing taxes, promoting healthy eating, decriminalizing marijuana, and promoting renewable energy. OMP nominated two candidates in the 2014 provincial election; party leader Yuri Duboisky ran in the riding of Richmond Hill and Ian Lytvyn ran in the riding of Etobicoke—Lakeshore. Neither candidate gained a seat in the Legislative Assembly of Ontario and the party received approximately 0.01% of the popular vote.
Sometimes ventilation is provided in addition to the drainage plane such as in rainscreen construction. Face-sealed also called barrier wall or perfect barrier cladding relies on maintaining a leak-free surface of the cladding. Examples of face sealed cladding are the early exterior insulation finishing systems, structural glazing, metal clad panels, and corrugated metal. Building walls frequently become works of art, externally and internally, such as when featuring mosaic work or when murals are painted on them; or as design foci when they exhibit textures or painted finishes for effect.
Cerebral autoregulation typically ensures that the correct amount of blood reaches the various regions of the brain to match the activity of the cells in that region. In other words, perfusion typically matches metabolism in all organs; especially in the brain, which gets the highest priority. However, following a seizure it has been shown that sometimes cerebral blood flow is not proportionate to metabolism. While cerebral blood flow didn’t change in the mouse hippocampus (the foci of seizures in this model) during or after seizures, increases in relative glucose uptake were observed in the region during the ictal and early postictal periods.
Similarly, the distance d2 between the centers of the solution circle and C2 is either or , again depending on their chosen tangency. Thus, the difference between these distances is always a constant that is independent of rs. This property, of having a fixed difference between the distances to the foci, characterizes hyperbolas, so the possible centers of the solution circle lie on a hyperbola. A second hyperbola can be drawn for the pair of given circles C2 and C3, where the internal or external tangency of the solution and C2 should be chosen consistently with that of the first hyperbola.
Coordinate systems are essential for studying the equations of curves using the methods of analytic geometry. To use the method of coordinate geometry, the axes are placed at a convenient position with respect to the curve under consideration. For example, to study the equations of ellipses and hyperbolas, the foci are usually located on one of the axes and are situated symmetrically with respect to the origin. If the curve (hyperbola, parabola, ellipse, etc.) is not situated conveniently with respect to the axes, the coordinate system should be changed to place the curve at a convenient and familiar location and orientation.
The intervention strategies to eradicate cysticercosis includes surveillance of pigs in foci of transmission and massive chemotherapy treatment of humans. In reality, control of T. solium by a single intervention, for instance, by treating only human population will not work because the existing infected pigs can still carry on the cycle. The proposed strategy for eradication is to do multilateral intervention by treating both human and porcine populations. It is feasible because treating pigs with oxfendazole has been shown to be effective and once treated, pigs are protected from further infections for at least 3 months.
Deep brain stimulation of the anterior nuclei of the thalamus is approved for DRE in some countries in Europe, but has been and continues to only be used in a very few patients. After 5 years of DBS a seizure reduction of 69% and a 50%-responder rate of 68% was reported in a randomized-double blinded trial. The rate of serious device related events was 34% in this study. Responsive neurostimulation (RNS) is approved for DRE in the USA and involves stimulation directly to 1 or 2 seizure foci when abnormal electrocorticographic activity is detected by the devices software.
Bistatic range refers to the basic measurement of range made by a radar or sonar system with separated transmitter and receiver. The receiver measures the time difference of arrival of the signal from the transmitter directly, and via reflection from the target. This defines an ellipse of constant bistatic range, called an iso-range contour, on which the target lies, with foci centred on the transmitter and receiver. If the target is at range Rrx from the receiver and range Rtx from the transmitter, and the receiver and transmitter are a distance L apart, then the bistatic range is Rrx+Rtx-L.
In 1609, Johannes Kepler, using his teacher's (Tycho Brahe) accurate measurements, noticed the inconsistency of a heliocentric model where the sun is exactly in the centre. Instead Kepler developed a more accurate and consistent model where the sun is located not in the centre but at one of the two foci of an elliptic orbit. Kepler derived the three laws of planetary motion which changed the model of the Solar System and the orbital path of planets. The three laws of planetary motion are: # All planets orbit the Sun in elliptical orbits (image on the left) and not perfectly circular orbits.
The Orr Focus is a regional manifestation of the Upper Mississippian Oneota cultures which were present throughout the American Midwest in the late Prehistoric and Protohistoric to early Historic periods. The subsistence base of the Orr Focus people, like most Upper Mississippians, was primarily agricultural supplemented by hunting, fishing and gathering. The Orr Focus is distinctive from other Oneota Foci mainly in terms of the pottery which is based on rectilinear (instead of curvilinear) decoration and frequent notching on the lip. This pottery was first noted at the Upper Iowa River Oneota Site Complex and was designated Allamakee Trailed.
DTF found multiple applications, the early ones involved: localization of epileptic foci, estimation of EEG propagation in different sleep stages and wakefulness, determination of transmission between brain structures of an animal during a behavioral test. One may observe the shifting of sources toward the front in transition from wakefulness to the deeper sleep stages. In the deep sleep the source is over corpus callosum, presumably it is connected with feeding the cortex from the sub-cortical structures. One of the first applications of SDTF was determination of the dynamic propagation during performance of finger movement and its imagination,.
Over the next day, about eight thousand islanders, including soldiers, sailors, civilians and members of the PRC like Petrichenko, escaped the island and sought refuge in Finland. The sailors sabotaged part of the fortifications before abandoning them, but the battleship crews refused to take them off the island and were willing to surrender to the Soviets. In the early hours March 18, a group of cadets took control of the boats. At noon there were only small foci of resistance and the authorities already had control of the forts, the fleet's boats and from almost the entire city.
Commenting on the title song he credited it to be extremely impressive and the same time groovy at first listen. The mix of hip hop, Indian and Western sounds with a tad of Hariyanvi flavour and lyrics by Kumaar with the entertainment of masses being its foci working in the songs tremendous recall value. This is extended by the addition of another 'remix' version of the song and a theme version with vocals by Sonu Kakkar and Khushboo Grewal. The second song, "Hum Na Tode," is an adapted track of hugely popular Tamil song composed by Vidyasagar, Appadi Podu.
It is in fact one of the foci used by the elves to channel ancient magics. He worries that if the orb's origin were to be revealed, it may have negative consequences for the reputation of the elven people. He then guides the Inquisitor to Skyhold, a disused fortress located in the Frostback Mountains that the Inquisition could claim as its new headquarters. When the Inquisitor finally defeats Corypheus and stops him from opening another rift, with the orb being damaged permanently in the process, Solas seems distraught and laments the destruction of the orb as the loss of yet another elven artifact.
Micrograph of the spleen showing darkly stained, spheroid Gamna-Gandy bodies (arrows) outside the vessel wall at the center. Also shown is diffusely scattered, brown, granular hemosiderin pigment (arrowheads), indicating previous hemorrhage (hematoxylin & eosin staining, 40x magnification). Gandy–Gamna nodules or Gandy-Gamna bodies, sometimes known as Gamna-Gandy bodies or Gamna-Gandy nodules, are small yellow-brown, brown, or rust-colored foci found in the spleen in patients with splenomegaly due to portal hypertension, as well as sickle cell disease. They consist of fibrous tissue with haemosiderin and calcium deposits, and probably form due to scarring at sites of small perivascular haemorrhages.
In prokaryotes, RNase H2 is enzymatically active as a monomeric protein. In eukaryotes, it is an obligate heterotrimer composed of a catalytic subunit A and structural subunits B and C. While the A subunit is closely homologous to the prokaryotic RNase H2, the B and C subunits have no apparent homologs in prokaryotes and are poorly conserved at the sequence level even among eukaryotes. The B subunit mediates protein-protein interactions between the H2 complex and PCNA, which localizes H2 to replication foci. Both prokaryotic and eukaryotic H2 enzymes can cleave single ribonucleotides in a strand.
In an effort to systematize Moon's teachings, several members of the Unification Church in Korea have put together a developing theological system in Divine Principle which is impressive in its imaginative nature, coherence, and consistency, if not in its Christian orthodoxy. As the most complete expression of Moonist teachings to date, Divine Principle is the basic text of the Unification Church.4 The two major divisions of the system are the doctrines of Creation and Restoration. There are many subsets to these major divisions, but Creation and Restoration are the foci for the Moonist theological system.
Guaranteed minimum income became a central theme of social policy in the mid-1980s, through the publications of the Academy. Starting with a study day entitled From quantity to quality of life, a book of the same name arose, and from it the fictional series Social Foci. At the end of the 1980s, the Academy played a decisive role in preparing the first Austrian poverty conference, which was held in Salzburg at the end of 1995. The creeping erosion of Sunday was countered by the Sunday Alliance, which was broadly based and included churches, trade unions, and economic and civil society organizations.
The model must be infinitely divisible as c2−p approaches infinity. In nontechnical terms this theorem implies that any exponential dispersion model that asymptotically manifests a variance-to-mean power law is required to have a variance function that comes within the domain of attraction of a Tweedie model. Almost all distribution functions with finite cumulant generating functions qualify as exponential dispersion models and most exponential dispersion models manifest variance functions of this form. Hence many probability distributions have variance functions that express this asymptotic behaviour, and the Tweedie distributions become foci of convergence for a wide range of data types.
These gatherings, called olturax, grew to perform important political and economic functions in Yining life. Islamic youth groups organized in the evenings grew in opposition to and eventually eclipsed the olturax, also serving "the foci for Uyghur resistance to Chinese rule". Calling themselves "meshreps", the clubs criticized the secular nature of the olturax and the alcohol consumption within as un-Islamic. These meshreps, which have been compared to the Catholic Knights of Columbus, were more formal than the olturax: tasked with providing "moral guidance", they kept strict membership lists and organized regular meetings, wherein members would read passages from the Quran.
Changing between the Cassegrain and Nasmyth foci takes a matter of seconds and may be done during the night; switching to and from prime focus requires replacing the secondary mirror with a prime focus assembly during daytime (the two are mounted back-to-back) which takes around 30 minutes. A Coudé focus was planned as a later addition, to feed an optical interferometer with another telescope, but this was never built. A chopping f/35 secondary mirror was planned for infrared observations, but was placed on hold by the cost-saving re-design and never implemented.
The upcoming generation of extremely large telescopes (ELTs) will require sophisticated adaptive optics in order to be used to their full capability. Because the WHT has an advanced adaptive optics system already operating, it is receiving attention from the various ELT programs. The European Southern Observatory's European-ELT (E-ELT) project has begun a programme to utilise the WHT as a test-bed for its adaptive optics system, and will receive several nights per year for on-sky testing. The project involves construction of new optical experiments at one of the Nasmyth foci, and is called CANARY.
At another level, Shmotkin examined long-term traumatic effects by national data from the Israeli branch of Survey of Health, Ageing and Retirement in Europe (SHARE-Israel). Shmotkin and his collaborators delineated the notion of cumulative adversity, which typically characterized stressful experiences along biographical courses of older people, and further differentiated between self-oriented (primary harm was to the self) and other- oriented (primary harm was to another person) foci of potentially traumatic events. The investigatory team found that cumulative adversity, particularly of the self-oriented kind, was detrimental in various domains of physical and mental functioning.
Despite his winning the school's scripture biography prize in his second year, his academic work remained unnoticed until, at the age of 13, he won the school's mathematical medal and first prize for both English and poetry. Maxwell's interests ranged far beyond the school syllabus and he did not pay particular attention to examination performance. He wrote his first scientific paper at the age of 14. In it he described a mechanical means of drawing mathematical curves with a piece of twine, and the properties of ellipses, Cartesian ovals, and related curves with more than two foci.
Microscopically, the tumor cells recapitulate embryonic sensory retina or nonpigmented ciliary epithelium. The chalky grayish-white particles within the tumor mass correspond to foci of cartilage on histology; the semi-translucent membrane covering the lens in some tumors corresponds to spreading neoplastic cells. Tumor cells form a characteristic diktyomatous pattern, with folded cords and sheets resembling a fisherman's net. In early development of the retina, the medullary epithelial cells acquire polarity, such that a basement membrane associated with the vitreous forms the internal limiting membrane on one side, while terminal bars form the outer limiting membrane on the other side.
Coordinate systems are essential for studying the equations of curves using the methods of analytic geometry. To use the method of coordinate geometry, the axes are placed at a convenient position with respect to the curve under consideration. For example, to study the equations of ellipses and hyperbolas, the foci are usually located on one of the axes and are situated symmetrically with respect to the origin. If the curve (hyperbola, parabola, ellipse, etc.) is not situated conveniently with respect to the axes, the coordinate system should be changed to place the curve at a convenient and familiar location and orientation.
However, most areas with such a high concentration of Fort Ancient sites employ only a single method of burial. Because the area around the Bone Mound II shows evidence of multiple methods of burial, it may have been occupied by multiple foci of the Fort Ancient people; consequently, the region is very valuable archaeologically. On July 15, 1974, the Bone Mound II was listed on the National Register of Historic Places because of its potential to be an archaeological site. The Bone Stone Graves, the cemetery with limestone vaults, was listed on the Register on the same day.
Because most Fort Ancient sites include only a single type of burials, rather than both a mound and a cemetery, it is believed that the vicinity of the Stone Graves may have been inhabited by people of two different foci. In the future, more information may be gained from the cemetery, for the site has never been subject to an archaeological excavation. On July 15, 1974, the Bone Stone Graves were listed on the National Register of Historic Places because of their archaeological value. The Bone Mound II was listed on the Register on the same day.
When light passes through a slice of calcite cut perpendicular to its optic axis, the difference between the propagation times of the ordinary and extraordinary waves has a second-order dependence on the angle of incidence. If the slice is observed in a highly convergent cone of light, that dependence becomes significant, so that a chromatic-polarization experiment will show a pattern of concentric rings. But most minerals, when observed in this manner, show a more complicated pattern of rings involving two foci and a lemniscate curve, as if they had two optic axes.Jenkins & White, 1976, pp. 576–9 (§27.9, esp. Fig. 27M).
Neuronal death does not appear to contribute to the learning deficits in rats with infant seizures. CA3 neurons in the tetanus toxin model of early onset epilepsy, however, show a reduction in the branching complexity of basal dendrites as well as a decrease in the spine density on both the apical dendrites and the basal dendrites. Similar data have been taken from epileptic human patients during surgical procedures. In neocortical and hippocampal foci, a decrease in length and branching complexity of dendritic arbors and a reduction in the branching complexity of the remaining dendrites were observed.
Early settlements and regions of 16th-century Honduras The first four decades of conquest were a turbulent period; domination of Honduras was not achieved until 1539. The initial foci of Spanish settlement were Trujillo, Gracias a Dios, and the areas around Comayagua and San Pedro Sula. Unlike in Mexico, where centralised indigenous power structures assisted swift conquest, there was no unified political organisation to overthrow; this hindered the incorporation of the territory into the Spanish Empire. Sometimes the Spanish would conquer an area and move on, just for it to immediately rise in rebellion, or massacre the Spanish colonisers.
Buber made this theme the basis of a famous definition of the tension between Judaism and Christianity: > Pre-messianically, our destinies are divided. Now to the Christian, the Jew > is the incomprehensibly obdurate man who declines to see what has happened; > and to the Jew, the Christian is the incomprehensibly daring man who affirms > in an unredeemed world that its redemption has been accomplished. This is a > gulf which no human power can bridge.Martin Buber, "The Two Foci of the > Jewish Soul", cited in The Writings of Martin Buber, Will Herberg (editor), > New York: Meridian Books, 1956, p. 276.
Almost all distribution functions with finite cumulant generating functions qualify as exponential dispersion models and most exponential dispersion models manifest variance functions of this form. Hence many probability distributions have variance functions that express this asymptotic behavior, and the Tweedie distributions become foci of convergence for a wide range of data types. Much as the central limit theorem requires certain kinds of random variables to have as a focus of convergence the Gaussian distribution and express white noise, the Tweedie convergence theorem requires certain non-Gaussian random variables to express 1/f noise and fluctuation scaling.
In early October 1817, at the urging of the Countess Elding, wife of the Duke of Weimar and spokesperson of the Philomousos Eteria of Vienna, he went to Jena. There he was influenced by the movement of liberalism of which the University of Jena was one of the major foci. The murder of a student and the riots which followed made the Greek students leave the city and continue their studies at the University of Göttingen. He heard about the Revolution when he was in Berlin and he immediately decided to return to serve in the Greek revolution.
Barycentric view of the Pluto–Charon system as seen by New Horizons The barycenter is one of the foci of the elliptical orbit of each body. This is an important concept in the fields of astronomy and astrophysics. If a is the distance between the centers of the two bodies (the semi-major axis of the system), r1 is the semi-major axis of the primary's orbit around the barycenter, and is the semi-major axis of the secondary's orbit. When the barycenter is located within the more massive body, that body will appear to "wobble" rather than to follow a discernible orbit.
Another significant design point was that the city itself was nestled in between Mount Ainslie and Mount Bimberi and used their collective picturesque amenity as visual foci for the street layout and to convey civic power. Hence, the Griffins aligned democracy with the most powerful force of all: nature. Consequentially, given it was so severely overshadowed, the traditional methodology of using grand architecture to convey power was rendered less significant. This approach was strongly influenced by Pierre Charles L’Enfant's 1792 design for Washington, D.C. L’Enfant's design included wide, tree-lined avenues that would visually connect significant topographical sites over the city.
The Berlin School of Economics was among the first business schools in Germany to offer MBA-programmes through its Berlin Professional School (formerly known as Institute of Management Berlin (IMB)) and can look back on 15 years of experience in this field. The BPS’s core competence is the MBA programme, and especially MBAs with different key themes. The five accredited MBA programmes of the BPS aim to prepare graduates – with various foci – for leading positions in general management of businesses or in the healthcare sector. The BPS offers also three M.A. programmes and one certificate programme.
Professor Helene Denise Marsh FAA FTSE (born 8 April 1945) is an Australian scientist who has provided research in the field of Environmental Science, more specifically Zoology and Ecology. The focal point of her research has been the biology of dugongs, with particular foci in the areas of population ecology, history, reproduction, diet, and movements. She is the Dean of Graduate Research Studies and the Professor of Environmental Science at James Cook University in Queensland, Australia, and also a Distinguished Professor in the College of Marine and Environmental Science. Marsh is also a program leader for the Marine and Tropical Research Science Facility.
Using the mammary tumor virus-polyoma middle T-antigen (MMTV-PyMT) mouse model of mammary tumorigenesis, it was shown that reduced Sam68 expression decreases tumor burden and metastasis. Kaplan-Meier curves showed that loss of one sam68 allele (PyMT; Sam68+/-) was associated with a significant delay in the onset of palpable tumors and a significant reduction in tumor multiplicity. These findings suggest that Sam68 is required for PyMT-induced mammary tumorigenesis. The knockdown of Sam68 expression in PyMT-derived mammary cells reduced the number of lung tumor foci in athymic mice, suggesting that Sam68 is also required for mammary tumor metastasis.
The histology of EST is variable, but usually includes malignant endodermal cells. These cells secrete alpha-fetoprotein (AFP), which can be detected in tumor tissue, serum, cerebrospinal fluid, urine and, in the rare case of fetal EST, in amniotic fluid. When there is incongruence between biopsy and AFP test results for EST, the result indicating presence of EST dictates treatment. This is because EST often occurs as small "malignant foci" within a larger tumor, usually teratoma, and biopsy is a sampling method; biopsy of the tumor may reveal only teratoma, whereas elevated AFP reveals that EST is also present.
During SSEs, LFE foci migrate along strike at the subduction interface in concert with the primary shear slip front. The depth occurrence of low frequency earthquakes is in the range of approximately 20–45 kilometers depending on the subduction zone, and at shallower depths at strike-slip faults in California. At "warm" subduction zones like the west coast of North America, or sections in eastern Japan this depth corresponds to a transition or transient slip zone between the locked and stable slip intervals of the plate interface. The transition zone is located at depths approximately coincidental with the continental Mohorovicic discontinuity.
Martin and Grube 2000, p.29. Sharer and Traxler 2006, p.321. During the Early Classic period (c. 250–600) the Mundo Perdido became one of the twin foci of the city, the other being the North Acropolis.Martin and Grube 2000, p.29. From AD 250 to 378 it may have served as the royal necropolis. The Mundo Perdido complex was given its name by the archaeologists of the University of Pennsylvania; it is centered upon the Lost World Pyramid and a small platform to the west of it. Group G lies just south of the Mendez Causeway.
And, the use of concepts and notions requires a notion of sameness not difference; the fact of 'repeatability', 'distribution' or 'continuity' in respect of 'cognition' of things indicates multiple instances of their presence or absence or the very expectation of what is to be obtained or avoided. Even that which can be qualified by a negation has anvaya. Dharmakirti is of the view that for the construction of the sameness required by anvaya certain limits (avadhis) are required to be placed on the causes and effects which are the foci, and which cannot be without some notion of sameness.
TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interactions of RNA-binding proteins. J. Biol. Chem. 289. 4653-4659. Small-molecule ligands, composed primarily of lead, can target GGGGCC repeat regions as well and ultimately decreased both repeat-associated non-ATG translation and RNA foci in neuron cells derived from patients with Amyotrophic lateral sclerosis (ALS). This provides evidence that small- molecule ligands are an effective and efficient process to target GGGGCC regions, and that specificity for small-molecule ligand binding is a feasible goal for the scientific community.
Generally speaking, great powers are faced with a lower level of external threat in comparison to small states and thus have more options for action. This increased range of choice will tend to make foreign policy formation more susceptible to domestic political influences. Consequently, unit level variables cannot be ignored when explaining great power foreign policy.” She continues to quote Snyder where he points out the importance of the size of state when its foreign policy is being analysed: “Similarly, Snyder assumes that the study of small state and great power behaviour require different analytical foci.
This gene encodes the protein for complementation group D2. This protein is monoubiquitinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 and BRCA2) involved in homology- directed DNA repair (see Figure: Recombinational repair of DNA double-strand damages). A nuclear complex containing FANCA, FANCA, FANCB, FANCC, FANCE, FANCF, FANCL and FANCG proteins is required for the activation of the FANCD2 protein to the mono-ubiquitinated isoform. Mono-ubiquination of FANCD2 is essential for repairing DNA interstrand crosslinks, and clamps the protein on DNA together with its partner protein FANCI.
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others.
Inhibition or loss of MDC1 protein through studies with siRNA on human cells or knockout studies in mice have shown several defects at both the cellular and organismal level. Mice lacking MDC1 are smaller, have infertile males, are radiosensitive, and are more susceptible to tumors. Knock out MDC1 mice cells and silenced human cells were radiosensitive, failed to initiate Intra-S phase and G2/M checkpoints, failed to produce ionizing radiation-induced foci had poor phosphorylation by the DRR kinases (ATM, CHK1, CHK2), defects in homologous recombination. Human cells with silenced MDC1 also displayed random plasmid integration, reduced apoptosis, and slowed mitosis.
Yet until the 1980s, such researchers were scarce, largely via scarce funding for such investigations. Despite the limited funding, research established that L forms can adhere to red blood cells and thereby disseminate from foci within internal organs such as the spleen,Gerald J Domingue, Cell Wall- Deficient Bacteria: Basic Principles and Clinical Significance (Reading MA: Addison-Wesley Publishing, 1982), p 455. or from oral tissues and the intestines, especially during dysbiosis. Perhaps some of Weston Price's identified "toxins" in endodontically treated teeth were L forms, thought nonexistent by bacteriologists of his time and widely overlooked into the 21st century.
Although the International Academy of Oral Medicine & Toxicology claims that the scientific evidence establishing the existence of jawbone cavitations is overwhelming, and even published in textbooks, the diagnosis and related treatment remain controversial,IAOMT, "IAOMT position paper on jawbone osteonecrosis", International Academy of Oral Medicine & Toxicology, 27 Jul 2014. and allegations of quackery persist.Stephen Barrett, "A critical look at cavitational osteopathosis, NICO, and 'biological dentistry'", Quackwatch, 4 Apr 2010. Huggins and many biological dentists also espouse Weston Price's findings on endodontically treated teeth routinely being foci of infection, although these dentists have been accused of quackery.
Most practices of nanotechnology and materials science today have foci distinct from Feynman's ultimate vision of manipulating individual atomic position and spin, which may be better described by "Atomic engineering", that addresses characteristic length scales from 1 femtometer (the atomic nucleus size) to 1 nanometer (about 5 atoms across in linear dimension). Coherent quantum control of individual atomic defect like the Nitrogen-vacancy center, and the eventual "3D atom printing" ("2D atom printing" was realized in 1990 by IBMD. M. EIGLER and E. K. SCHWEIZER, "Positioning single atoms with a scanning tunnelling microscope", Nature 344 (1990) 524-526.
The circles of Apollonius are any of several sets of circles associated with Apollonius of Perga, a renowned Greek geometer. Most of these circles are found in planar Euclidean geometry, but analogs have been defined on other surfaces; for example, counterparts on the surface of a sphere can be defined through stereographic projection. The main uses of this term are fivefold: # Apollonius showed that a circle can be defined as the set of points in a plane that have a specified ratio of distances to two fixed points, known as foci. This Apollonian circle is the basis of the Apollonius pursuit problem.
140–41 According to López-Rey, the painting has three focal points: the Infanta Margaret Theresa, the self-portrait and the half-length reflected images of King Philip IV and Queen Mariana. In 1960, the art historian Kenneth Clark made the point that the success of the composition is a result first and foremost of the accurate handling of light and shade: However, the focal point of the painting is widely debated. Leo Steinberg argues that the orthogonals in the work are intentionally disguised so that the picture's focal center shifts. Similar to Lopez-Rey, he describes three foci.
Relationship between fully differentiated "old" cells, pluripotent stem cells produced through classical cloning, and "young" cells produced by partial cloning. In the field of cell biology, the method of partial cloning (PCL) converts a fully differentiated old somatic cell into a partially reprogrammed young cell that retains all the specialised functions of the differentiated old cell but is simply younger. The method of PCL reverses characteristics associated with old cells. For example, old, senescent, cells rejuvenated by PCL are free of highly condensed senescence-associated heterochromatin foci (SAHF) and re-acquire the proliferation potential of young cells.
The book Manual de español urgente (Manual of Emerging Spanish), first published in 1985, is an important tool in helping media in the use of Spanish, including clarifications on the meanings of neologisms from many fields (hidrofracturación, itinerar, cibercondría, and so on). It is also responsible for clearing up any misunderstandings pertaining to the Spanish language. One of the main foci of the manual has been to provide alternatives to English words and phrases that have begun to influence the language. The manual also clears up any misinterpretations of how proper Spanish would utilize diverse linguistic aspects, such as pronunciation, orthography, and punctuation.
Like many other figures of this era, he was subject to religious and political troubles, like the Thirty Years War, which led to chaos that almost destroyed some of his works. Kepler was, however, the first to attempt to derive mathematical predictions of celestial motions from assumed physical causes. He discovered the three Kepler's Laws of Planetary Motion that now carry his name, those laws being as follows: #The orbit of a planet is an ellipse with the Sun at one of the two foci. #A line segment joining a planet and the Sun sweeps out equal areas during equal intervals of time.
Madeira is the largest island of the group with an area of , a length of (from Ponta de São Lourenço to Ponta do Pargo), while approximately at its widest point (from Ponta da Cruz to Ponta de São Jorge), with a coastline of . It has a mountain ridge that extends along the centre of the island, reaching at its highest point (Pico Ruivo), while much lower (below 200 metres) along its eastern extent. The primitive volcanic foci responsible for the central mountainous area, consisted of the peaks: Ruivo (1,862 m), Torres (1,851 m), Arieiro (1,818 m), Cidrão (1,802 m), Cedro (1,759 m), Casado (1,725 m), Grande (1,657 m), Ferreiro (1,582 m).
After the end of the war, he spent another 2 years in the waters of the River Plate, and in 1831 he was sent back to Rio de Janeiro. From the abdication of the Emperor D. Pedro I in 1831, he dedicated himself to fighting the revolting foci throughout the country, going from north to south. Still in 1831, combat in the northeast, in Pernambuco, Pará, Recife and Ceará. He was appointed to command the Brigue Cacique in 1834, which he commanded throughout his performance in the Farroupilha Revolt. In 1840 he was already Captain of Frigate and, in 1847, Captain of Sea and War.
These works identified Chicago's leading architects and the challenges to building and planning they faced after the great fire of 1871. Then Condit produced a two-volume history of Chicago (Condit, 1973, 1974), books whose prime foci were architectural and technological, but which included a broad range of urban history as well. Many of the architectural masterpieces of the 1890s and 1920s were dilapidated or threatened by the 1950s, and Condit joined battles for their preservation where possible, often testifying at hearings on decisions about protecting landmark buildings. He also gave architectural tours of Chicago and frequently wrote newspaper and magazine pieces about the city's buildings.
A funerary stele depicting an ancient Roman family The New Testament Household Codes (Haustafeln), also known as New Testament Domestic Codes, consist of instructions in the New Testament writings of the apostles Paul and Peter to pairs of Christian people in different domestic and civil structures of society. The main foci of the Household Codes are upon husband/wife, parent/child, and master/slave relationships. The Codes apparently were developed to urge the new first century Christians to comply with the non- negotiable requirements of Roman Patria Potestas law, and to meet the needs for order within the fledgling churches.Stagg, Evelyn and Frank Stagg.
James Griffin, upon examining the artifacts from the original 1929 excavations, felt that Huber was a Component of the Oneota Aspect based on the form and design of the pottery, close to the Orr and Lake Winnebago foci, and that Fisher was part of a separate Focus. Since that date, we’ve obtained a great deal more information and now we know that Fisher is the older of the two and Huber is the one that survived to the Historic period. Nevertheless, both Fisher and Huber coexist at the same sites seemingly at the same time. Hoxie Farm, Griesmer and Moccasin Bluff are examples of this.
If the pseudorange between the receiver and satellite i and the pseudorange between the receiver and satellite j are subtracted, , the common receiver clock bias (b) cancels out, resulting in a difference of distances . The locus of points having a constant difference in distance to two points (here, two satellites) is a hyperbola on a plane and a hyperboloid of revolution in 3D space (see Multilateration). Thus, from four pseudorange measurements, the receiver can be placed at the intersection of the surfaces of three hyperboloids each with foci at a pair of satellites. With additional satellites, the multiple intersections are not necessarily unique, and a best-fitting solution is sought instead.
The quantum corral was demonstrated in 1993 by Lutz, Eigler, and Crommie using an elliptical ring of iron atoms on a copper surface using the tip of a low-temperature scanning tunneling microscope to manipulate individual atoms. The ferromagnetic iron atoms reflected the surface electrons of the copper inside the ring into a wave pattern, as predicted by the theory of quantum mechanics. The size and shape of the corral determine its quantum states, including the energy and distribution of the electrons. To make conditions suitable for the mirage the team at Almaden chose a configuration of the corral which concentrated the electrons at the foci of the ellipse.
When scientists placed a magnetic cobalt atom at one focus of the corral, a mirage of the atom appeared at the other focus. Specifically the same electronic properties were present in the electrons surrounding both foci, even though the cobalt atom was only present at one focus. In scanning tunneling microscopy, an atomically sharp metal tip is advanced towards the atomically flat sample surface until electron tunneling out of the atom and into the advancing tip becomes effective. Using the sharp tip we can also arrange atoms adsorbed on the surface into unique shapes; for example, 48 adsorbed iron atoms on Cu(111) arranged into a 14.26 nm diameter circle.
A nucleus typically contains between 1 and 10 compact structures called Cajal bodies or coiled bodies (CB), whose diameter measures between 0.2 µm and 2.0 µm depending on the cell type and species. When seen under an electron microscope, they resemble balls of tangled thread and are dense foci of distribution for the protein coilin. CBs are involved in a number of different roles relating to RNA processing, specifically small nucleolar RNA (snoRNA) and small nuclear RNA (snRNA) maturation, and histone mRNA modification. Similar to Cajal bodies are Gemini of Cajal bodies, or gems, whose name is derived from the Gemini constellation in reference to their close "twin" relationship with CBs.
This condition has been reported in patients with Ehlers Danlos syndrome,Park MA, Shin SY, Kim YJ, Park MJ, Lee SH (2017) Vascular Ehlers-Danlos syndrome with cryptorchidism, recurrent pneumothorax, and pulmonary capillary hemangiomatosis-like foci: A case report.Medicine (Baltimore) 96(47):e8853 CREST syndromeDiao XL, Mu XD, Jin ML (2017) Pulmonary capillary hemangiomatosis associated with CREST syndrome: A challenge of diagnosis and treatment. Chin Med J (Engl) 130(21):2645-2646 and scimitar syndrome.Güttinger E, Vrugt B, Speich R, Ulrich S, Schwitz F, Arrigo M, Huber LC (2016) Reactive pulmonary capillary hemangiomatosis and pulmonary veno-acclusive disease in a patient with repaired scimitar syndrome.
In some cases, subduction zones show two parallel surfaces of seismicity separated by tens of kilometres at intermediate depths (50–200 km). A primary example of this is located along Japan's largest island of Honshu, where the Wadati–Benioff zone is characterized by two well-defined lines of earthquake foci, with a distance between each line of 30–40 kilometers. A study of the global prevalence of double Benioff zones has found that they are common in subduction zones worldwide. The uppermost seismicity surface is in the crust of the down-going slab and attributed to the dehydration reactions within this oceanic crust resulting in the formation of eclogite.
Before that, all students receiving an undergraduate degree would be required to study the same slate of courses geared at a comprehensive "liberal education". In 1825, the University of Virginia initiated an educational approach that would allow students to choose, from eight options, an area of focus (ex: ancient languages, anatomy, medicine) and higher educational systems in Europe after the American civil war developed further into a stricter specialization approach to studies. In the United States, in the second half of the 19th century, concentrated foci at the undergraduate level began to prosper and popularize, but the familiar term "major" did not appear until 1877 in a Johns Hopkins University catalogue.
Using their prediction database INFORNA, they discovered that a compound could bind to 1 x 1 UU internal loops on an N-methyl peptide backbone. They confirmed that like other compounds that target DM1 r(CUG), they could inhibit the complex between r(CUG)-MBNL1, disrupt nuclear foci, and increase nucleocytoplasmic transport of the gene in patient-derived DM1 fibroblasts. In that study the Disney group also described several approaches to validate the RNA targets of small molecules. In the first approach termed chemical cross-linking and isolation by pull down (Chem-CLIP) and chemical cross-linking and isolation by pull down to map binding sites (Chem-CLIP-Map).
Congenital cortical blindness is most often caused by perinatal ischemic stroke, encephalitis, and meningitis. Rarely, a patient with acquired cortical blindness may have little or no insight that they have lost vision, a phenomenon known as Anton–Babinski syndrome. Cortical blindness and cortical visual impairment (CVI), which refers to the partial loss of vision caused by cortical damage, are both classified as subsets of neurological visual impairment (NVI). NVI and its three subtypes—cortical blindness, cortical visual impairment, and delayed visual maturation—must be distinguished from ocular visual impairment in terms of their different causes and structural foci, the brain and the eye respectively.
While published at nearly the same time, both papers served as landmark publications introducing the idea of life occurring during the Precambrian. Each paper had markedly different foci: while Barghoorn and Tyler 1965 aimed to characterize the individual microorganisms that comprise the Gunflint chert from a taxonomical and morphological standpoint, Cloud 1965 focused on the larger-scale significance of the prospect of life existing during the Precambrian period, and its implications for the field of Precambrian paleontology. The publication of these two seminal papers opened the floodgates to a vast array of paleontological and geochemical studies to explore Precambrian microfossils from similar Proterozoic environments.
In addition to formal classes, Bard Graduate Center runs a series of evening colloquia designed to function in a kind of polyphony with the “for credit” course offerings. Regular evening seminars, which are open to the academic public, serve as foci. In addition, the History and Theory of Museums program brings in speakers affiliated with current exhibitions, and the Medieval, Renaissance, and Early Modern Europe group cosponsors two annual events with the Columbia University interdepartmental group on Medieval and Renaissance studies. The endowed lecture series bring in a regular sequence of speakers on eighteenth- and nineteenth-century France and on the history of glass.
Peripheral ossifying fibroma, also known as ossifying fibrous epulis, is “a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementum-like tissue, or a dystrophic calcification. The lesion is considered part of an ossifying fibroma, but that is usually considered to be a jaw tumor. Because of its overwhelming incidence on the gingiva, the condition is associated with two other diseases, though not because they occur together. Instead, the three are associated with each other because they appear frequently on gingiva: pyogenic granuloma and peripheral giant cell granuloma.
In 1994, Polakow-Suransky began teaching math and social studies at Crossroads Middle School in Harlem. After three years, he became the founding math teacher and eventually assistant principal at Bread and Roses Integrated Arts High School, which combined foci on arts and social justice in its curriculum. Inspired by New York City's small schools movement and aware of the added struggles that English language learners face, Polakow-Suransky founded a new, small school, Bronx International High School, in 2001. In order to be admitted to the school, students had to fail the City's English language assessment and had to be recent immigrants to the United States.“Bronx International High School”.
Varro (1st century BC)Varro, Divine Antiquities, book 5, frg. 65. distinguishes among the di superi ("gods above"), whose sites for offerings are called altaria; the di terrestres ("terrestrial gods"), whose altars are arae; and di inferi, to whom offerings are made by means of foci, "hearths," on the ground or in a pit. In general, animal sacrifice to gods of the upper world usually resulted in communal meals, with the cooked victim apportioned to divine and human recipients. Infernal gods, by contrast, received burnt offerings (holocausts), in which the sacrificial victims were burnt to ash, because the living were prohibited from sharing a meal with the dead.
During his Parisian period, Rosso also began to experiment with photography in his studio, and he photographed the works under a variety of lighting conditions, foci, and compositions in order to capture different impressions of these three-dimensional works, often further manipulating the printing process and cropping, folding, scratching, or painting the photographic prints to create focused glimpses of the sculptural subjects.Sharon Hecker, "Life, Work, and Era," in Medardo Rosso: Experiments in Light and Form (St. Louis: Pulitzer Arts Foundation, 2016), 17-20. As a sculptor, one of Rosso's principal concerns was to subject the physical mass of sculpture to the transient and ephemeral effects of light.
Because the sites were foci for power of which old mean > were meant to have exclusive control, the flouting of site entry > restrictions and site disturbance by Europeans ... had important effects Over the decades that followed Queensland authorities felt it necessary to progressively encourage and often forcibly remove Kuku Nyungkal people from the tin mining areas and associated external settlement, into lands specially reserved for the purpose such as Ayton, Hopevale, Yarrabah, and other reserves.Anderson, C & Coastes, S (1989) "Like a Crane Standing on One Leg on a Little Island". Research Study No. 1. The Underlying Causes for the Deaths of Australian Aboriginal People in Government Detention.
EIT has been suggested as a basis for brain imaging to enable detection and monitoring of cerebral ischemia, haemorrhage, and other morphological pathologies associated with impedance changes due to neuronal cell swelling, i.e. cerebral hypoxemia and hypoglycemia. While EIT’s maximum spatial resolution of approximately 15% of the electrode array diameter is significantly lower than that of cerebral CT or MRI (about one millimeter), temporal resolution of EIT is much higher than in CT or MRI (0.1 milliseconds compared to 0.1 seconds). This makes EIT also interesting for monitoring normal brain function and neuronal activity in intensive care units or the preoperative setting for localization of epileptic foci by telemetric recordings.
In the mid-1990s, Kühne's research foci shifted to the history of war, genocide and masculinities in the 20th Century. Taking up strands of previously established Anglophone scholarship, his volume on men's history in modern Germany (Männergeschichte-Geschlechtergeschichte, 1996) established this field in Central Europe and stimulated a broad range of innovative studies since then. Covering the period from 1918 to 1995, the monograph Kameradschaft (2006) asks how the myth of comradeship prefigured and shaped the war experience of Hitler's soldiers and war memory in Germany through the end of the century. [1] Kühne's first English book goes further in encompassing the entire German society rather than only the soldiers.
In the 1990s a sociology of human consciousness was developed by Burns, Erik Engdahl, Nora Machado, and Sviatoslav Korepov based on sociology and social psychology traditions, in particular inspired by George Herbert Mead. In addition, a number of new theoretical concepts such as social structuring, meta-power and relational control, organizational dissonance and contradiction, and public policy paradigm theory were formulated and applied in empirical investigations. On a policy oriented level, the risks of complex socio-technical systems, the emergence of post-parliamentary democracy and new forms of governance, and the instabilities and ecological and social destructiveness of capitalism have been particular foci of attention since the early 1990s.
However, not all the results of researches devoted to the study of the laws and mechanisms of cytomorphogenesis of epithelioid cells fit into the concept the origin of epithelioid cells from macrophages. Deimann J and Fahimi H (1980) showed that epithelioid cells in granulomas, induced in the rat liver by injection of glucan, beta-1,30-polyglucose, are formed not from Kupffer cells - mature differentiated macrophages, but from blood monocytes. De Vos et al. (1990) obtained the data that allowed them to suggest that in granulomatous inflammation foci, in granulomatous lymphadenitis, epithelioid cells be formed not from differentiated macrophages, but from so-called plasmacytoid monocytes (have similarities with plasmacytes).
A Rich focus is a tuberculous granuloma occurring within the cortex or meninges of the brain that ruptures into the subarachnoid space, causing tuberculous meningitis. The Rich focus is named for Arnold Rice Rich, a pathologist at Johns Hopkins Hospital, who along with his colleague Howard McCordock first described the post-mortem finding of caseous foci within the cerebral cortex or meninges which appeared to predate the development of meningitis. Prior to their research the prevailing view had been that meningitis occurred as a result of the dissemination of tuberculous bacilli associated with miliary tuberculosis and that these processes occurred at the same time.
The Roman Empire in the time of Hadrian (ruled AD 117–138), showing, in western Asia, the imperial province of Arabia Petraea (Jordan/NW Saudi Arabia/Sinai). A single legion was deployed there in 125 AD. The geographic makeup of Arabia has some variation. It includes the comparatively fertile Moab plateau, which received 200mm of annual rainfall, at the southernmost tip of which lies Petra which, along with Bostra (or Busra), together constitute the political foci of the province. Inhospitability is the norm, though, and along with the desert proper that is the Sinai, the arid Negev, which extends north of the Sinai, is practically such.
Eukaryotic recombinases that are homologues of RecA are also widespread in eukaryotic organisms. For example, in fission yeast and humans, RecA homologues promote duplex-duplex DNA-strand exchange needed for repair of many types of DNA lesions. Another indication that DNA damages are a major problem for life is that cells make large investments in DNA repair processes. As pointed out by Hoeijmakers, repairing just one double-strand break could require more than 10,000 ATP molecules, as used in signaling the presence of the damage, the generation of repair foci, and the formation (in humans) of the RAD51 nucleofilament (an intermediate in homologous recombinational repair).
The decision of the referee Christos Nicolaides was instrumental in the evolution of the race, since Laborde is the number one risk for rival foci after the elimination of the "Lady", which was better up to that point, they actually threatened. The elimination of Laborde then, but the fault of the match was Colin, since the 71' not colluded with Kozáčik and "gave" the goal of victory in the Kingdom. He stayed at 27 degrees the "Lady" and risk losing valuable ground in the race for first place. On the other hand, three points may seem "gold" in the effort of Aris to remain in First Division.
If the water's surface is disturbed at one focus of an elliptical water tank, the circular waves of that disturbance, after reflecting off the walls, converge simultaneously to a single point: the second focus. This is a consequence of the total travel length being the same along any wall-bouncing path between the two foci. Similarly, if a light source is placed at one focus of an elliptic mirror, all light rays on the plane of the ellipse are reflected to the second focus. Since no other smooth curve has such a property, it can be used as an alternative definition of an ellipse.
Rutka was a leader in his application of neurosurgical techniques to pediatric neurosurgical patients with a variety of neurosurgical disorders including craniofacial anomalies, brain tumours, congenital malformations, and epilepsy. With his colleagues, he helped introduce digital camera technology to assist with mapping of intra-operative seizure foci. He was among the first to utilize frameless stereotactic neuronavigation techniques to resect cerebral and skull base lesions in children; and he has amassed a large neurosurgical experience in treating children with epilepsy arising from lesions within highly eloquent and critical regions of the brain. In addition, Rutka and colleagues have used magnetoencephalography (MEG) to identify regions of epileptogenesis amenable to neurosurgical resection.
Diphyllobothriasis occurs in areas where lakes and rivers coexist with human consumption of raw or undercooked freshwater fish. Such areas are found in Europe, newly independent states of the former Soviet Union, North America, Asia, Uganda, Peru (because of ceviche), and Chile. Many regional cuisines include raw or undercooked food, including sushi and sashimi in Japanese cuisine, carpaccio di persico in Italian, tartare maison in French-speaking populations, ceviche in Latin American cuisine and marinated herring in Scandinavia. With emigration and globalization, the practice of eating raw fish in these and other dishes has brought diphyllobothriasis to new parts of the world and created new endemic foci of disease.
Historians debate whether Otto von Bismarck—Minister President of Prussia—had a master plan to expand the North German Confederation of 1866 to include the remaining independent German states into a single entity or simply to expand the power of the Kingdom of Prussia. They conclude that factors in addition to the strength of Bismarck's led a collection of early modern polities to reorganize political, economic, military, and diplomatic relationships in the 19th century. Reaction to Danish and French nationalism provided foci for expressions of German unity. Military successes—especially those of Prussia—in three regional wars generated enthusiasm and pride that politicians could harness to promote unification.
LCIS often have the same genetic alterations (such as loss of heterozygosity on chromosome 16q, the locus for the e-cadherin gene) as the adjacent area of invasive carcinoma. These observations, along with genomic analysis for clonal relationships between the cells of LCIS and ILC, support LCIS as being a precursor to ILC, and that the lesions encompassed by the broader category of Lobular Neoplasia (LN) fall on a linear spectrum of progression. LCIS is often found concurrently with foci of invasive carcinoma and multiple studies have shown, using genetic sequencing techniques, that synchronous LCIS and ILC share clonal cell populations, or originate from the same line of mutated cells.
Under Notger's administration, following up on the work of Heraclius, educational institutions in Liège flourished. With these two bishops (and Wazo) "The schools of Liège were, in fact, at that time one of the brightest literary foci of the period". In the 11th century the city was indeed known as the Athens of the North. "Liège for more than a century occupied among the nations a position in regard to science which it has never recovered". Subsequent bishops, Balderic of Looz (1008–18), Wolbodo (1018–21), Durandus (1021–25), Reginard (1025–38), Nitard (1038–42), the learned Wazo, and Theoduin (1048–75), valiantly sustained the heritage of Notger.
Pott's puffy tumor can be associated with cortical vein thrombosis, epidural abscess, subdural empyema, and brain abscess. The cause of vein thrombosis is explained by venous drainage of the frontal sinus, which occurs through diploic veins, which communicate with the dural venous plexus; septic thrombi can potentially evolve from foci within the frontal sinus and propagate through this venous system. This type of chronic osteomyelitis of the frontal bone is confused with acute sub-periosteal abscess of the frontal bone, which presents as a discrete collection over the frontal sinus. Although it can affect all ages, it is mostly found among teenagers and adolescents.
The disease heals within a few weeks. Bovine mammillitis is characterized by lesions restricted to the teats and udder. BoHV-2 probably spreads through an arthropod vector, but can also be spread through milkers and milking machines. A review publication from 2011 presents a series of controversial but scientifically based conclusions concerning the pathogenesis and epidemiology of the infection, among these that spread among cattle is preferably by the respiratory route, and that skin lesions result from viremic spread to epidermal foci and inflammation due to complement activation by the classical pathway at sites of virus propagation after formation of early antibody to BoHV2.
The Late Woodland peoples with their emphasis on small villages and hunting and gathering adaptation had previously occupied the Upper Mississippi Valley and Great Lakes Region prior to A.D. 1000. In some areas, the Late Woodland population persisted until European contact, and even occasionally coexisted in the same time and place with the Upper Mississippians. Most of the Upper Mississippian entities are grouped together under the Oneota Aspect. The Grand River, Lake Winnebago, Koshkonong, Green Bay (aka Mero Complex), Orr and Utz are Foci grouped under Oneota. Fisher and Huber are placed by James A. Brown in an ‘unnamed tradition” (or Focus) within the Oneota Aspect.
Lionel Claude Briand, born in Paris, France on November 21, 1965, is a software engineer, and professor at the University of Ottawa and University of Luxembourg. He is an IEEE Fellow, a Canada Research Chair in Intelligent Software Dependability and Compliance and a European Research Council Advanced grantee. His research foci are testing, verification, and validation of software systems; applying machine learning and evolutionary computation to software engineering; and software quality assurance, among others. He was Vice-director of the University of Luxembourg's SnT - Interdisciplinary Centre for Security, Reliability and Trust from 2014 to 2019, and editor in chief of Empirical Software Engineering (Springer) from 2003 to 2016.
Gavett G, "Tragic results when dental care is out of reach"4, PBS Frontline website, 26 Jun 2012 But only alternative medicine and later biological dentistry continued highlighting sites of dental treatment—still endodontic therapy, but, more recently, also dental implant, and even tooth extraction, too—as foci of infection causing chronic and systemic diseases.Hal A Huggins & Thomas E Levy, Uninformed Consent: The Hidden Dangers in Dental Care (Charlottesvi4lle VA: Hampton Roads Publishing, 1999), ch 12 "The cavitation" & ch 13 "Focal infection". In mainstream dentistry and medicine, the primary recognition of focal infection is endocarditis, if oral bacteria enter blood and infect the heart, perhaps its valves.
Harry's skill with battle magic has increased steadily and quickly. His shields are the most striking example, initially unable to deal with sufficiently strong attacks, and not warding away heat, such that his hand was almost burned off. Now, thanks to practice and improved foci, they can deal with significant attacks without a problem. While the head of the Wardens has sufficient focus to wield fire magic with a pinpoint laser-like effect that can cut a person in two, Harry has the power to take out a building, fry an I-beam, and has 'upgraded' to a blue-white shot of fire magic strong enough to bore through a Denarian.
FANCF is an adaptor protein that plays a key role in the proper assembly of the FA core complex. The FA core complex is composed of eight proteins (FANCA, -B, -C, -E, -F, -G, -L and -M). FANCF stabilizes the interaction between the FANCC/FANCE subcomplex and the FANCA/FANCG subcomplex and locks the whole FA core complex in a conformation that is essential to perform its function in DNA repair. The FA core complex is a nuclear core complex that is essential for the monoubiquitination of FANCD2 and this modified form of FANCD2 colocalizes with BRCA1, RAD51 and PCNA in foci that also contain other DNA repair proteins.
This gene encodes the protein for complementation groufcrp E. A nuclear complex containing FANCE protein (as well as FANCC, FANCF and FANCG) is essential for the activation of the FANCD2 protein to the mono- ubiquitinated isoform. In normal, non-mutant cells, FANCD2 is mono-ubiquinated in response to DNA damage. FANCE together with FANCC acts as the substrate adapter for this reaction Activated FANCD2 protein co-localizes with BRCA1 (breast cancer susceptibility protein) at ionizing radiation-induced foci and in synaptonemal complexes of meiotic chromosomes. Activated FANCD2 protein may function prior to the initiation of meiotic recombination, perhaps to prepare chromosomes for synapses, or to regulate subsequent recombination events.
Under standard assumptions, a body moving under the influence of a force, directed to a central body, with a magnitude inversely proportional to the square of the distance (such as gravity), has an orbit that is a conic section (i.e. circular orbit, elliptic orbit, parabolic trajectory, hyperbolic trajectory, or radial trajectory) with the central body located at one of the two foci, or the focus (Kepler's first law). If the conic section intersects the central body, then the actual trajectory can only be the part above the surface, but for that part the orbit equation and many related formulas still apply, as long as it is a freefall (situation of weightlessness).
Despite being a Bourbon defeat, it left behind so many mainland foci for anti-French resistance that Napoleon then decided to abandon his plan to capture Sicily. It did, however, reverse the balance of power established at Maida the previous year and guaranteed French control of Calabria until 1815, when Ferdinand IV was returned to the throne by the Congress of Vienna. Murat then made a failed attempt to re-conquer Naples and was shot at Pizzo on 13 October 1815 after a summary trial, with the kingdoms of Naples and Sicily reunified in 1816 under Ferdinand IV, who restyled himself Ferdinand I of the Two Sicilies.
The boundaries of these zones will be ellipsoids with foci at the transmitter and receiver. In order to ensure limited interference, such transmission paths are designed with a certain clearance distance determined by a Fresnel-zone analysis. The dependence on the interference on clearance is the cause of the picket-fencing effect when either the radio transmitter or receiver is moving, and the high and low signal strength zones are above and below the receiver's cut-off threshold. The extreme variations of signal strength at the receiver can cause interruptions in the communications link, or even prevent a signal from being received at all.
Other foci of his apologetics have included challenging the methodology, assumptions and conclusions drawn in higher criticism of the Old Testament and form and redaction criticism of the gospels. His work in this area has consisted of a popular summary of scholarly debate, particularly from Evangelical discussions about higher critical theories. In the late 1980s and into the 1990s his apologetic writings interacted with challenges expressed in popular books like The Holy Blood and the Holy Grail, The Lost Years of Jesus, and the writings of the humanist George A. Wells. He has also collated apologetic arguments concerning the doctrine of Christ's deity as in Jesus: A Biblical Defense of His Deity.
Problem 1 then explores the case of a circular orbit, assuming the center of attraction is on the circumference of the circle. A scholium points out that if the orbiting body were to reach such a center, it would then depart along the tangent. (Proposition 7 in the Principia.) Problem 2 explores the case of an ellipse, where the center of attraction is at its center, and finds that the centripetal force to produce motion in that configuration would be directly proportional to the radius vector. (This material becomes Proposition 10, Problem 5 in the Principia.) Problem 3 again explores the ellipse, but now treats the further case where the center of attraction is at one of its foci.
In recent years, there has been something of a resurgence in rural studies, which has become somewhat more mainstream than previously in the academic space of social science. Increasing numbers of people have taken on important dualistic questions of society/space, nature/culture structure/agency and self/other from the perspective of rural studies. However, it is the 'cultural turn' in wider social science which has lent both respectability and excitement to the nexus with rurality, particularly with new foci on landscape, otherness and the spatiality of nature. With a conceptual fascination with difference, and a methodological fascination with ethnography, cultural studies have provided a significant palimpsestuous overlay onto existing landscapes of knowledge.
Virginia Mennonite Conference is overseen by Conference Council, an appointed group that makes larger decisions about the work of the Conference, appoints overseers for the different districts and commissions, and through the Faith & Life Commission, credentials ministers. Congregations appoint delegates to represent them at two meetings a years to discern issues and vote on resolutions. Within the Conference structure are two Commissions that work on specific foci. The Congregational Life Commission "provides vision for new expressions of Anabaptism, provides the means for congregations, conference- related programs and institutions to communicate and network their ministries, and provides educational resources for congregations to nurture the spiritual formation of their members throughout the life cycle," according to a list of Commission duties.
Its first issue included articles by UK Development Secretary Douglas Alexander, General David Petraeus, Head of US Central Command, Mary Kaldor and Ian Goldin and Tiffany Vogel of Oxford University. The journal's first edition defines its six main foci # Globally relevant risks and collective action problems # International policy coordination # Normative theories of global governance # The change from national-level to 'bloc'-level policy making # The transition from single-polar to multipolar governance # Innovations in global governance According to the Journal Citation Reports, the journal has a 2014 impact factor of 0.603, ranking it 95th out of 161 journals in the category "Political Science" and 49th out of 85 journals in the category "International Relations".
In 1949, Hugo Benioff introduced a method for determining elastic-rebound strain increments of earthquakes on a particular fault. He determined that the square root of an earthquake's energy is proportional to both the elastic rebound strain increment and the rebound displacement, and developed a way to determine whether a series of earthquakes was generated along a single fault structure. His research focused on the Kermadec-Tonga subduction zone and the South American subduction zone, and determined that in both locations, earthquake foci fall along planes dipping ~45° from the trenches. These planes of seismicity were later termed Benioff zones, or Wadati–Benioff zones for Kiyoo Wadati, who made similar observations independent of Benioff at the same time.
Levi died on 1 August 1870 and is buried at Cwmfelin Mynach in the Ramoth Baptist graveyard. On the death certificate the cause of death is given as "Consumption". Levi is one of the foci of a PhD that was submitted to University of Wales Lampeter in the 1990s. It can be viewed at the Library and also requested for Inter-Library Loan. The details are: Parry- Jones, Lilian: Astudiaeth o Faledi Levi Gibbon, Thomas Harris a Stephen Jones, yn ogystal â Rhai Baledi Eraill o’r Un Cylch, Traethawd PhD Prifysgol Cymru (Llanbedr Pont Steffan), 1992. See also Parry-Jones, Lilian: ‘Baledi Levi Gibbon, Thomas Harris, Stephen Jones, ac Eraill’, Llên Cymru, 19 (1996), tt.85-129.
Alongside the regular monthly publication, the magazine has released a number of special issues, such as the July 2008 special issue that spoke out for the preservation of the opera house of the Berlin State Opera as designed by Richard Paulick. International theatre is one of the main editorial foci. Each September issue is published in two languages and contains the portrait of a specific country. To date, these issues have focused on theatre in Finland (2014), The Netherlands and Flanders (2013), London (2012), Iran (2011), Cuba (2010), South Africa (2009), Chile (2008), Canada (2007), Japan (2006), France (2005), Mexico (2004), Italy (2003), the Baltic States (2002), the Netherlands (2001), Poland (2000), and Russia (1999).
Before she was married, Isabella worked at the Ackworth School, a Quaker school for the poor, assisting her widowed mother who was the superintendent of the school. His father was a pioneer in the design of achromatic object lenses for use in compound microscopes; he spent 30 years perfecting the microscope, and in the process, discovered the Law of Aplanatic Foci, building a microscope where the image point of one lens coincided with the focal point of another. Up until that point, the best higher magnification lenses produced an excessive secondary aberration known as a coma which interfered with normal use. His work built a reputation sufficient to enable his being elected to the Royal Society in 1832.
How proteins become localised to different parts of the cell — such as to the endoplasmic reticulum, Golgi apparatus or the plasma membrane — and the role of this in cell polarity, have been elucidated by Bretscher, Hugh Pelham and Sean Munro. The spindle pole bodies — the large structures in yeast cells which act as the foci to which chromosomes are moved during mitosis — have been purified and a low resolution structure of them deduced by John Kilmartin. A continuing interest has been the structure of chromosomes. This was initiated by a visitor, Roger Kornberg, who discovered the first level of condensation of DNA, the nucleosome, and continues with the focus on understanding the higher orders of folding DNA.
Models have been proposed in various contexts ranging from turbulence in fluid dynamics to internet traffic, finance, image modeling, texture synthesis, meteorology, geophysics and more. The origin of multifractality in sequential (time series) data has been attributed to mathematical convergence effects related to the central limit theorem that have as foci of convergence the family of statistical distributions known as the Tweedie exponential dispersion models, as well as the geometric Tweedie models. The first convergence effect yields monofractal sequences, and the second convergence effect is responsible for variation in the fractal dimension of the monofractal sequences. Multifractal analysis is used to investigate datasets, often in conjunction with other methods of fractal and lacunarity analysis.
Unitelma Sapienza, through the use of advanced information technology and methodologies in distance learning, promotes access to higher education to students who are unable to attend regular educational activities. The university pays particular attention to the development of research, in particular within scientific and economic sectors, as well as in management of information technology, with particular attention to theories, models, processes, technologies and applications for the development of a virtual campus through the internet. A special focus is given to tutoring: the university offers tutors concerned with academic activities, student motivation, and the achievement of student career goals. The university aims to combine the foci to increase interactivity with students for a more cooperative learning environment.
The CDC lists the following areas as active foci of human epidemic typhus: Andean regions of South America, some parts of Africa; on the other hand, the CDC only recognizes an active enzootic cycle in the United States involving flying squirrels (CDC). Though epidemic typhus is commonly thought to be restricted to areas of the developing world, serological examination of homeless persons in Houston found evidence for exposure to the bacterial pathogens that cause epidemic typhus and murine typhus. A study involving 930 homeless people in Marseilles, France found high rates of seroprevalence to R. prowazekii and a high prevalence of louse-borne infections in the homeless. Typhus has been increasingly discovered in homeless populations in developed nations.
The present unpopularity of MDA is not only due to doubts regarding the health benefit of this intervention but to the fear that MDAs will facilitate the spread of drug resistance. Concern that MDA would cause pyrimethamine and later chloroquine resistance was first raised in the early 1960s. Circumstantial evidence linked the use of medicated salts to the emergence of chloroquine resistance in the 1980s: Chloroquine resistance emerged first in three foci, namely South America (Colombia, Venezuela, Brazil), Southeast Asia (Thailand/Kampuchea), and Africa (Tanzania/Kenya). Payne has argued that the one common factor between these three epidemiologically diverse areas was widespread distribution of medicated salts prior to the emergence of chloroquine resistance.
The number of DUF1220 domains present in the human genome correlates with both brain size and the amount of neurons present in the brain. Additionally, higher copy numbers of the DUF1220 domain are associated with increasing Autism severity, which often results from an excess of neurons that do not under synaptic pruning. Predicted Structure of Stat-1 and Stat3b-like DNA binding domains in NBPF1 using Phyre2 The NBPF1 protein is also found to be disrupted by a chromosomal translocation between chromosomes 1 and 17 with in some cases of human neuroblastoma. Additional studies show that NBPF1 is possibly a tumor suppressor gene because adding it to cell cultures lowers the incidence of foci formation.
Reed's research focuses on the design of very high-speed computers, providing new computing capabilities for scholars in science, medicine, engineering and the humanities, tools and techniques for capturing and analyzing the performance of parallel systems, and collaborative virtual environments for real-time performance analysis. He led the Pablo Research Group, which investigates the interaction of architecture, system software, and applications on large-scale parallel and distributed computer systems. The group created SvPablo, a graphical environment for instrumenting application source code and browsing dynamic performance data. Key research foci of the group included exploration of performance analysis techniques and compiler- aided scalability analysis, scalable parallel file systems, and real-time adaptive systems for resource policy control.
Epigenetic changes of this type thus have the potential to direct increased frequencies of permanent genetic mutation. DNA methylation patterns are known to be established and modified in response to environmental factors by a complex interplay of at least three independent DNA methyltransferases, DNMT1, DNMT3A, and DNMT3B, the loss of any of which is lethal in mice. DNMT1 is the most abundant methyltransferase in somatic cells, localizes to replication foci, has a 10–40-fold preference for hemimethylated DNA and interacts with the proliferating cell nuclear antigen (PCNA). By preferentially modifying hemimethylated DNA, DNMT1 transfers patterns of methylation to a newly synthesized strand after DNA replication, and therefore is often referred to as the ‘maintenance' methyltransferase.
Rocio viral encephalitis is an epidemic flaviviral disease of humans first observed in São Paulo State, Brazil, in 1975. Low-level enzootic transmission is likely continuing in the epidemic zone, and with increased deforestation and population expansion, additional epidemics caused by Rocio virus are highly probable. If migratory species of birds are, or become involved in, the virus transmission cycle, the competency of a wide variety of mosquito species for transmitting Rocio virus experimentally suggest that the virus may become more widely distributed. The encephalitis outbreak in the western hemisphere caused by West Nile virus, a related flavivirus, highlights the potential for arboviruses to cause severe problems far from their source enzootic foci.
Bernard Ginsburg House Stiefel wrote that by the 1970s the exodus of Jews from the City of Detroit to the suburbs had increased from a "trickle" to a "deluge." There were 80,000 Jews living in Metro Detroit in 1976, of a total population of 4,138,800, and in the metro area there were 34 congregations: 23 Orthodox, 6 Conservative, 4 Reform, and one Humanistic. In the 1980s the Metro Detroit Jewish community lived in several municipalities. Barry Steifel, author of The Jewish Community of Metro Detroit 1945-2005, wrote that in the 1980s "the new, collective foci of the Jewish community" were several municipalities in Oakland County and western Wayne County which housed "massive congregations".
Blastomyces dermatitidis is one of the most ecologically mysterious organisms causing human and animal disease. Prediction of disease risk and prevention of disease are both made extraordinarily difficult by our very poor understanding of where and how this organism normally grows in nature. Despite decades of attempts at isolating organisms from epidemiological foci, B. dermatitidis has only been isolated from the environment 21 times. Most of these isolations have been based on the arduous isolation techniques involving the suspension of soil or other environmental materials in aqueous medium with antibacterial antibiotics, and injection of mice with these materials, followed by sacrifice of the animals when they appear ill or at the end of six weeks.
If successful, the only remaining endemic locations would be in Africa and Yemen. In Africa, it is estimated that greater than 102 million people in 19 countries are at high risk of onchocerciasis infection, and in 2008, 56.7 million people in 15 of these countries received community-directed treatment with ivermectin. Since adopting such treatment measures in 1997, the African Programme for Onchocerciasis Control reports a reduction in the prevalence of onchocerciasis in the countries under its mandate from a pre-intervention level of 46.5% in 1995 to 28.5% in 2008. Some African countries, such as Uganda, are also attempting elimination and successful elimination was reported in 2009 from two endemic foci in Mali and Senegal.
The School of Humanities at Rice University in Houston, in the U.S. state of Texas allows students to choose from ten academic departments including art history, classical studies, English, French studies, German studies, Hispanic studies, history, philosophy, religious studies, and visual and dramatic arts. Several interdisciplinary majors are also available, such as foci on women, gender and sexuality; Asian studies; ancient Mediterranean civilizations; and medieval and early modern studies. The school is home to six national journals: SEL: Studies in English Literature 1500–1900 the Journal of Southern History, the Journal of Feminist Economics, Papers of Jefferson Davis, the Religious Studies Review, and the Council of Societies for the Study of Religion Bulletin. The Humanities Building opened in 2000.
Grossly, LAM lungs are enlarged and diffusely cystic, with dilated air spaces as large as several centimeters in diameter. Microscopic examination of the lung reveals foci of smooth muscle-like cell infiltration of the lung parenchyma, airways, lymphatics, and blood vessels associated with areas of thin-walled cystic change. LAM lesions often contain an abundance of lymphatic channels, forming an anastomosing meshwork of slit-like spaces lined by endothelial cells. LAM cells generally expand interstitial spaces without violating tissue planes but have been observed to invade the airways, the pulmonary artery, the diaphragm, aorta, and retroperitoneal fat, to destroy bronchial cartilage and arteriolar walls, and to occlude the lumen of pulmonary arterioles.
When Antony died, Octavian became uncontested ruler of Rome. In the following years, Octavian, who was known as Augustus after 27 BC, managed to accumulate in his person all administrative, political, and military offices. When Augustus died in AD 14, his political powers passed to his adopted son Tiberius; the Roman Empire had begun. The rise of Caesar and the subsequent civil war between his two most powerful adherents effectively ended the credibility of the Roman oligarchy as a governing power and ensured that all future power struggles would centre upon which one individual would achieve supreme control of the government, eliminating the senate and the former magisterial structure as important foci of power in these conflicts.
The lexicon of the original Ithkuil consisted of the same pattern as the current form of the language. However, each root consisted of 2 consonantal radicals, and could derive thousands of lexemes through the use of Ithkuil's complex rules of morphophonology, which involved both consonantal and vocal mutation, shifts in syllabic stress and tone, and affixation. Ithkuil words can be divided into just two parts of speech, formatives and adjuncts. Formatives functioned both as nouns and as verbs, depending on the morphosemantic context. Formatives were inflected for the current grammatical categories, plus 2 foci, and 81 cases; they could also have taken on some of the 153 affixes, which further qualified into one of 9 degrees.
A number of biochemical and molecular genetic mechanisms are known that enable malignant cells to invade surrounding tissues and gain the ability to spread far beyond the primary tumor site, giving rise to the development of secondary metastatic foci in distant organs and tissues. However, despite the achieved progress, there remain unexplored questions concerning a possible relationship between different types of invasive cell growth and the parameters of lymphogenous and hematogenous metastasis, the features of disease progression, as well as the efficacy of the chosen therapy. A solution to these problems could be of great help in determining the disease prognosis and, possibly, developing new approaches to the management of cancer patients.
Bernoulli's brother Jacob Bernoulli also studied the same curve in the same year, and gave it its name, the lemniscate.. It may also be defined geometrically as the locus of points whose product of distances from two foci equals the square of half the interfocal distance.. It is a special case of the hippopede (lemniscate of Booth), with d=-c, and may be formed as a cross-section of a torus whose inner hole and circular cross-sections have the same diameter as each other. The lemniscatic elliptic functions are analogues of trigonometric functions for the lemniscate of Bernoulli, and the lemniscate constants arise in evaluating the arc length of this lemniscate.
In pathways that do not use p53 in inducing apoptosis, PML have been shown to interact with CHK2 and induce it to autophosphorylate to become active. In addition to those two apoptotic pathways, Fas-induced apoptosis relies on the PML-NBs to release FLICE-Associated huge protein, which then localizes to the mitochondria to promote the activation of Caspase-8. Beyond apoptosis, other studies have implicated PML-NBs in cellular senescence, particularly its induction. It has been shown to be involved with the formation of certain chromatin features of cells experiencing senescence, such as senescence-associated heterochromatin foci (SAHFs), which are believed to suppress the expression of growth-promoting factors and genes.
Each UT telescope is a Ritchey-Chretien Cassegrain telescope with a 22-tonne 8.2 metre Zerodur primary mirror of 14.4 m focal length, and a 1.1 metre lightweight beryllium secondary mirror. A flat tertiary mirror diverts the light to one of two instruments at the f/15 Nasmyth foci on either side, with a system focal length of 120 m, or the tertiary tilts aside to allow light through the primary mirror central hole to a third instrument at the Cassegrain focus. This allows switching between any of the three instruments within 5 minutes, to match observing conditions. Additional mirrors can send the light via tunnels to the central VLTI beam-combiners.
The evidence of deer bones here and at Bardsea in South Cumbria suggests a continuation of hunter- gathering alongside more settled, agricultural, means of living. Ehenside points up the use of wetland areas by Neolithic Cumbrians: the finds there were discovered when the Tarn was drained. "Wetland areas, whether open water or bog, were foci for beliefs and ritual practices alongside contemporary monuments, and it is, therefore, interesting to note there was a standing stone near Ehenside Tarn".Clare (2007), p. 22. South Cumbria, and especially Furness and Walney, is the area where most of the axe finds have been made (67 examples - accounting for half of the total of axe finds in Cumbria).
Naha was known to have made extensive studies on the structural geology of Precambrian era and was credited with compiling an integrated geological history of Precambrian rocks in Ghatsila in Singhbhum of Bihar and in Simla region. Through his studies, he estimated the time of formation and kinematic significance of deformation lamellae in quartz. Migmatites and its architecture, the geometry of reclined folds and the early precambrian terrance of the southern parts of India and central Rajasthan were some of the other foci of his studies. His studies also assisted in developing methodologies for the recognition of angular run conformity in metamorphic terraces as well as the coaxial refolding prior to non- coaxial deformation.
Local artists, especially poster artists, presented similarly compelling depictions of their own provincial perceptions. Fulford demonstrated the prominence of this work by mentioning that a high school in suburban Ottawa made imitating View of the World an assignment in its graphic arts class. He also noted that the result of this assignment was a worldwide variety of global foci from which the students viewed the world. The illustration—humorously depicting New Yorkers' self-image of their place in the world, or perhaps outsiders' view of New Yorkers' self-image—inspired many similar works, including the poster for the 1984 film Moscow on the Hudson; that movie poster led to a lawsuit, Steinberg v.
James Griffin, upon examining the artifacts from the original 1929 excavations, felt that Huber was a Component of the Oneota Aspect based on the form and design of the pottery, close to the Orr and Lake Winnebago foci, and that Fisher was part of a separate Focus. Since that date, we’ve obtained a great deal more information and now we know that Fisher is the older of the two and Huber is the only one that has been found in association with early Historic European trade goods. Nevertheless, both Fisher and Huber coexist at the same sites seemingly at the same time. Hoxie Farm, Griesmer and Moccasin Bluff are examples of this.
James Griffin, upon examining the artifacts from the original 1929 excavations, felt that Huber was a Component of the Oneota Aspect based on the form and design of the pottery, close to the Orr and Lake Winnebago foci, and that Fisher was part of a separate Focus. Since that date, we’ve obtained a great deal more information and now we know that Fisher is the older of the two and Huber is the only one that has been found in association with early Historic European trade goods. Nevertheless, both Fisher and Huber coexist at the same sites seemingly at the same time. Hoxie Farm, Griesmer and Moccasin Bluff are examples of this.
Stony Ridge Observatory is an astronomical observatory built by and for amateur astronomers in the mountains of Los Angeles County, California, in 1957. When installed, its Newtonian-Cassegrain likely ranked as 8th largest of all telescopes in California, and one of the largest amateur telescopes in the United States. The telescope is designed so that one of four Newtonian foci, or a Cassegrain focus, can be used. Asteroids 10168 Stony Ridge, 144633 Georgecarroll and 327030 Alanmaclure, were discovered at the observatory, and other scientific research (including an extensive lunar photography and mapping project in cooperation with Lockheed upon which the decision on the lunar lander touchdown site was based) has been conducted there.
In Paraguay, yerba mate continued to be a major cash crop after independence but the foci of industry shifted away from the mixed plantations and wild stands of Villarrica, north to Concepción in late colonial times and then by 1863 to San Pedro.Blinn Reber, Vera. Yerba Mate in Nineteenth Century Paraguay. 1985. During the rule of Carlos Antonio López (1844–1862), the yerba mate business was managed by the military commanders of the district, who could harvest yerba mate as a state enterprise or give concessions. The onset of the Paraguayan War (1864–1870) caused a sharp drop in the harvesting of yerba mate in Paraguay, estimated at 95% between 1865 and 1867, caused by enrolment.
Obviously coins and coinage were common - e.g. coins of emperor Louis the Pious were in use, but stamped with „Venecia“ on the reverse a figure -, but Venetians preferred the coins of Verona, although a Venetian zecca (Arabian word for coin) is verifiable for the ninth century already. Today's lagoon The early emporium of Torcello was soon replaced by Malamocco, later by Rialto. The nuclei around Olivolo, San Marco and Rialto made up three foci, one concentrated on ship building arsenal, one as political centre, one as centre of trade and exchange. The early phase of „feudalization“ together with the acquisition of wide real estates, brought huge amounts of capital to certain families.
Although physicians had already interpreted pus within a bodily compartment as a systemic threat, pus from infected tooth roots often drained into the mouth and thereby was viewed as systemically inconsequential. Amid focal infection theory, it was concluded that that was often the case—while immune response prevented dissemination from the focus—but that immunity could fail to contain the infection, that dissemination from the focus could ensue, and that systemic disease, often neurological, could result. By 1930, excision of focal infections was considered a "rational form of therapy" undoubtedly resolving many cases of chronic diseases. Its inconsistent effectiveness was attributed to unrecognized foci—perhaps inside internal organs—that the clinicians had missed.
Many of the long barrows were used as tombs in which to place the remains of deceased individuals. For this reason, archaeologists like Malone have referred to them as "houses of the dead". Conversely, many of the long barrows do not appear to have been used as tombs; various examples that have been excavated by archaeologists have shown no evidence of having had human remains deposited there. The archaeologists David Lewis-Williams and David Peace, however, noted that these long barrows were more than tombs, also being "religious and social foci", suggesting that they were places where the dead were visited by the living and where people maintained relationships with the deceased.
Molly is noted as being swarmingly effective on offense and elusive and hard to find on defense. In Cold Days, we get a much better idea of Harry's abilities as a Winter Knight. Losing all of his equipment at the end of Changes, Harry is forced to learn to fight without using foci or charms; this means his barriers are now only forward facing and his attacks are less focused. In return, the boost from his new station gives him access to much more mental power to cast from, and he can perform ice spells with ease, including freezing a virtual iceberg to save him and his friends from drowning in the cold waters.
Farrell addressing world conference of spiritual leaders, 2010 Dr. Warren Farrell speaking on the boy crisis at the University of Toronto, November 16, 2012 During the California gubernatorial recall election, Farrell ran as a Democratic candidate, on a platform of fathers' rights, and received 626 votes. Farrell's current foci are conducting communication workshops, being an expert witness in child custody cases and researching a forthcoming book (working title The Boy Crisis), to be co-authored with John Gray. In 2010–11, he keynoted, along with Deepak Chopra, a world conference on spirituality (the Integral Spiritual Experience), addressing the evolution of love. He was then invited by the Center on World Spirituality to be one of their world leaders.
In 1902, he realized that the two cemented interfaces had many virtues, so he reinserted them in the back of his Anastigmat, maintaining the "air gap" of the previous part of the Unar, thus creating the Tessar design (from the Greek word τέσσερα (téssera, four) to indicate a design of four elements) of 1902. The frontal element of the Tessar, like that of the Anastigmat, had little power since its only function was to correct the few aberrations produced by the powerful posterior element. The set of interfaces cemented in the posterior element had 3 functions: to reduce the spherical aberration; reduce the overcorrected spherical-oblique aberration; reduce the gap found between astigmatic foci.
Wakato Ferry between the straits Kanmonkyo Bridge is a vital traffic link in the region Transport in Fukuoka-Kitakyushu is similar to that of other large cities in Japan, but with a high degree of private transport. The region is a hub of international ferry services and has a high degree of air connectivity and a considerable rail transport network, complemented with highways and surface streets. It includes public and private rail and highway networks; airports for international, domestic, and general aviation; buses; motorcycle delivery services, walking, bicycling, and commercial shipping. The foci of the public transport system are Hakata Station, Tenjin Station, and Kokura Station, in Fukuoka and Kitakyushu cities respectively.
Yevgeny Pavlovsky was the president of the Soviet Geographical Society in 1952–1964. Under Pavlovsky's direction, they organized numerous complex expeditions to the Central Asia, Transcaucasus, Crimea, Russian Far East and other regions of the Soviet Union to study endemic parasitic and transmissible diseases (tick-borne relapsing fever, tick-borne encephalitis, Pappataci fever, leishmaniasis etc.). Yevgeny Pavlovsky introduced the concept of natural nidality of human diseases, defined by the idea that microscale disease foci are determined by the entire ecosystem. This concept laid the foundation for the elaboration of a number of preventive measures and promoted the development of the environmental trend in parasitology (together with the works of parasitologist Valentin Dogel).
Research staff in CSHL's 52 laboratories numbers over 600, including postdoctoral researchers; an additional 125 graduate students and 500 administrative and support personnel bring the total number of employees to over 1,200. Cell biology and genomics RNA interference (RNAi) and small-RNA biology; DNA replication; RNA splicing; signal transduction; genome structure; non-coding RNAs; deep sequencing; single-cell sequencing and analytics; stem cell self-renewal and differentiation; chromatin dynamics; structural biology; advanced proteomics; mass spectrometry; advanced microscopy. Cancer research Principal cancer types under study: breast, prostate, blood (leukemia, lymphoma); myelodysplastic syndrome; melanoma; liver; ovarian and cervical; lung; brain; pancreas. Research foci: drug resistance; cancer genomics; tumor microenvironment; cancer metabolism; growth control in mammalian cells; transcriptional and post-transcriptional gene regulation.
James Griffin, upon examining the artifacts from the original 1929 excavations at the Huber site, felt that Huber was a Component of the Oneota Aspect based on the form and design of the pottery, close to the Orr and Lake Winnebago foci, and that Fisher was part of a separate Focus. Since that date, we’ve obtained a great deal more information and now we know that Fisher is the older of the two and Huber is the one that survived to the Historic period, based on the association of Huber pottery with early Historic European trade goods at several sites. Nevertheless, both Fisher and Huber coexist at the same sites seemingly at the same time. Hoxie Farm, Griesmer and Moccasin Bluff are examples of this.
If the concentrations of phosphate and UO22+ are sufficiently high, minerals such as autunite (Ca(UO2)2(PO4)2•10-12H2O) or polycrystalline HUO2PO4 may form thus reducing the mobility of UO22+. Compared to the direct addition of inorganic phosphate to contaminated groundwater, biomineralization has the advantage that the ligands produced by microbes will target uranium compounds more specifically rather than react actively with all aqueous metals. Stimulating bacterial phosphatase activity to liberate phosphate under controlled conditions limits the rate of bacterial hydrolysis of organophosphate and the release of phosphate to the system, thus avoiding clogging of the injection location with metal phosphate minerals. The high concentration of ligands near the cell surface also provides nucleation foci for precipitation, which leads to higher efficiency than chemical precipitation.
As KSHV establishes latent infection in tumorous foci, it invariably expresses high levels of the viral LANA protein, which is necessary and sufficient to maintain the KSHV episome. Encoded by ORF73, LANA-1 is one of few HHV-8 encoded proteins that is highly expressed in all latently infected tumour cells; specifically, it is a phosphoprotein with an acidic internal repeat domain flanked by a carboxy-terminal domain and an amino- terminal domain. LANA-1 acts as a transcriptional regulator, and it has been implicated directly in oncogenesis because of its ability to bind to the tumour-suppressing protein p53 and to the retinoblastoma protein pRb. This leads to the inactivation of p53-dependent promoters and induction of E2F-dependent genes.
The semi-major (a) and semi-minor axis (b) of an ellipse In geometry, the major axis of an ellipse is its longest diameter: a line segment that runs through the center and both foci, with ends at the widest points of the perimeter. The semi-major axis is one half of the major axis, and thus runs from the centre, through a focus, and to the perimeter. The semi-minor axis of an ellipse or hyperbola is a line segment that is at right angles with the semi-major axis and has one end at the center of the conic section. For the special case of a circle, the lengths of the semi-axes are both equal to the radius of the circle.
Thomas's academic research is varied, with concentrations on the human response to environmental change in the Great Basin, as well as the consequences of Spanish exploration and colonization of the South on indigenous people in the region. One of Thomas's main foci is the relationship between Native American and anthropological communities. He has written extensively about the lawsuit against the federal government that prevented the repatriation of the Kennewick Man remains and has worked to support positive relationships between the scientific and native communities in North America. He believes that if better working relationships had been established before and during the Kennewick case, both sides could have come to an agreement without taking it to the level of the federal courts.
This thrust has both research and development aims, and complementary foci across the mathematics and science projects. The research aims are to contribute to scientific knowledge on the ‘what’ and ‘how’ of mathematics and science knowledge for teaching through substantive, ongoing research. This thrust focuses on pedagogic content knowledge and aims to carry out investigations into how subject experts, current and future educators, develop their Pedagogical Content Knowledge (PCK), and ways of capturing and portraying their use of PCK through case studies. The idea is to explore a number of issues such as models that are useful for describing and analysing teachers’ PCK, the resources and artifacts that educators employ, and the extent to which disciplinary knowledge is context bound.
Diagram of Wadati–Benioff zone, from the United States Geological Survey Seismicity cross-section, Kuril Islands subduction zone, 15 November 2006, 8.3 Mw event marked as star A Wadati–Benioff zone (also Benioff–Wadati zone or Benioff zone or Benioff seismic zone) is a planar zone of seismicity corresponding with the down-going slab in a subduction zone. Differential motion along the zone produces numerous earthquakes, the foci of which may be as deep as about . The term was named for the two seismologists, Hugo Benioff of the California Institute of Technology and Kiyoo Wadati of the Japan Meteorological Agency, who independently discovered the zones. Wadati–Benioff zone earthquakes develop beneath volcanic island arcs and continental margins above active subduction zones.
He is particularly known for his critiques of U.S. foreign policy and contemporary capitalism, and he has been described as a prominent cultural figure.Matt Dellinger, "Sounds and Sites: Noam Chomsky", The New Yorker, Link, 3-31-03, accessed 1-26-09 Chomsky, author of Occupy, in 2004. First emerging in New York City in 2011, the Occupy movement was an international protest movement against social and economic inequality, its primary goal being to make the economic structure and power relations in society more favorable to the underclasses. Different local groups have different foci, but among the prime concerns is the claim that large corporations and the global financial system control the world in a way that disproportionately benefits a minority, undermines democracy and is unstable.
A major function of BA 47 is language processing and comprehension. Although Broca’s and Wernicke’s areas are often the major foci of neuroanatomical studies related to language, research has discovered that these two areas are not as integral to language comprehension than originally thought; other structures like BA 47 play a major role. Specifically, BA 47 is active in tasks regarding semantics, or identifying the meaning of words and sentences. To understand language semantics, consider Dapretto and Bookheimer’s (1999) study where participants needed to identify that there was a difference between the sentences, “The man was attacked by the Doberman,” and “The man was attacked by the Pitbull.” While sentence form was similar, the words Doberman and Pitbull had different meanings, specifically dog breeds.
The T-S waves gradually increased in amplitude until a few random spikes of in-phase amplitude appeared, triggering focal vortices (turbulent spots), with noise. A further increase in flow rate resulted suddenly in many vortices, aerodynamic noise and a great increase in resistance to flow. An oscillation of a mass in a fluid creates a sound wave; SH oscillations of a mass of fluid, flowing in that same fluid along a boundary, must result in SH sound, reflected off the boundary, transversely into the fluid. S and S found foci of in-phase spiking amplitude in the T-S waves; these must create bursts of high amplitude sound, with high energy oscillation of fluid molecules transversely through the BL laminae.
Red-blue color contrast rectangles In 1885, Einthoven proposed a theory which states: "The phenomenon (chromostereopsis) is due to chromatic difference of magnification, for since, for example, blue rays are refracted more than red rays by the ocular media, their foci not only lie at different levels (chromatic aberration) but make different angles with the optic axis, and will thus stimulate disparate points. It follows that individuals with temporally eccentric pupils see red in front of blue, while with nasally eccentric pupils the relief is reversed." Einthoven first explained chromatic aberration in the eye, which means that the eyes will not focus all the colors at the same time. Depending on the wavelength, the focal point in the eyes varies.
There are several research publications on the eGranary, mainly by two scholars and their colleagues, each representing different research foci. Cliff Missen and colleagues have written several articles focussing on the contribution of the eGranary to low- bandwidth settings, notably Africa. Their research includes an overview of how the eGranary can provide web pages and multimedia files to under-resourced areas and counter the challenges of low bandwidth, as well as be an experiment to create metadata through crowd cataloging. Bonny Norton and colleagues at a rural community library in Uganda carry out another area of scholarly work on the eGranary. Their research discusses student and teacher library users’ identities in light of their use of the eGranary, which had been donated to the library.
Although the annual Saturday Book recorded in 1956 a view that "London's now nothing but flash coffee bars, with teddies and little bits of girls in jeans",Saturday Book, vol 16, 1956 the "Edwardian" ("teddy boy") look of the times did not coincide with Bohemian tastes. For women, the legacy of the "New Look" was still apparent, although hemlines had generally risen as, as one journalist put it in 1963, "photographs of those first bold bearers of the New Look make them seem strangely lost and bewildered, as though they had mistaken their cue and come on stage fifty years late".Pearson Phillips in Age of Austerity, op.cit. The Bohemian foci during this period were the jazz clubs and espresso bars of Soho and Fitzrovia.
The Parastaseis, dedicated to a doubtless imaginary "Philokalos", the generic "lover of beauty", are generally interpreted on the simplest level as a kind of tourist's guide to the curiosities of Constantinople, in the manner of the later guides to Rome, Mirabilia urbis Romae and De mirabilibus urbis Romae. In Classical Greek, a description of a work of art is an ekphrasis, and when considered under this rubric, or compared with the later compilation of notes on Constantinople called the Patria of Constantinople,Edited by Gilbert Dagron, Constantinople imaginaire: Etudes sur le recueil des "Patria", 1984. the Parastaseis fail to give an objective description. Instead, the reader is offered anecdotal narratives about the statues, which had become foci for legends and wonder-working objects themselves.
Some parts of the brain showing abnormal activity in OCD Functional neuroimaging during symptom provocation has observed abnormal activity in the orbitofrontal cortex, left dorsolateral prefrontal cortex, right premotor cortex, left superior temporal gyrus, globus pallidus externus, hippocampus and right uncus. Weaker foci of abnormal activity were found in the left caudate, posterior cingulate cortex and superior parietal lobule. However, an older meta analysis of functional neuroimaging in OCD reported the only consistent functional neuroimaging findings have been increased activity in the orbital gyrus and head of the caudate nucleus, while ACC activation abnormalities were too inconsistent. A meta analysis comparing affective and non affective tasks observed differences with controls in regions implicated in salience, habit, goal-directed behavior, self-referential thinking and cognitive control.
Although immigrant populations have increasingly become the foci for analyzing health disparities, the issue of providing care within the context of the patient's cultural background was contested by studies that completely denied the presence of rising health issues in immigrants due to inadequate health services. In 1986, theorists Kyriakos Markides and Jeannine Coreil developed the idea of the Healthy Migrant theory that thought of migration to include an inherent selection process due to the physical and psychological demands of travel, searching for employment, and adjusting to new cultural norm.Uretsky, Mathew Cory, and Sally G. Mathiesen. “The Effects of Years Lived in the United States on the General Health Status of California’s Foreign-Born Populations.” Journal of Immigrant and Minority Health, vol.
James B. Jordan maintains that, while children are indeed blessings, they are only one among a wide range of blessings God offers, and prayerfully choosing foci among them is part of prudent Christian stewardship. John Piper's Desiring God Ministries has published some comments that relate to Quiverfull: > Just because something is a gift from the Lord does not mean that it is > wrong to be a steward of when or whether you will come into possession of > it. It is wrong to reason that since A is good and a gift from the Lord, > then we must pursue as much of A as possible. God has made this a world in > which tradeoffs have to be made and we cannot do everything to the fullest > extent.
Lemniscate of Bernoulli In 1680, Cassini studied a family of curves, now called the Cassini oval, defined as follows: the locus of all points, the product of whose distances from two fixed points, the curves' foci, is a constant. Under very particular circumstances (when the half-distance between the points is equal to the square root of the constant) this gives rise to a lemniscate. In 1694, Johann Bernoulli studied the lemniscate case of the Cassini oval, now known as the lemniscate of Bernoulli (shown above), in connection with a problem of "isochrones" that had been posed earlier by Leibniz. Like the hippopede, it is an algebraic curve, the zero set of the polynomial (x^2 + y^2)^2 - 2a^2 (x^2 - y^2).
It has a mountain ridge that extends along the centre of the island, reaching at its highest point (Pico Ruivo), while much lower (below 200 metres) along its eastern extent. The primitive volcanic foci responsible for the central mountainous area, consisted of the peaks: Ruivo (1,862 m), Torres (1,851 m), Arieiro (1,818 m), Cidrão (1,802 m), Cedro (1,759 m), Casado (1,725 m), Grande (1,657 m), Ferreiro (1,582 m). At the end of this eruptive phase, an island circled by reefs was formed, its marine vestiges are evident in a calcareous layer in the area of Lameiros, in São Vicente (which was later explored for calcium oxide production). Sea cliffs, such as Cabo Girão, valleys and ravines extend from this central spine, making the interior generally inaccessible.
Both genetic and environmental factors (such as infection) can underlie such a transition from a neuroprotective autoimmune response into an overwhelming and detrimental autoimmune disease. Other cell types, such as B cells and even neural progenitor cells, can promote regulation of immune response in the CNS. Stem and progenitor cells are usually regarded with respect to their potential to serve as a source for newly differentiated cells, but recently stem and progenitor cells have also been acknowledged for their ability to modulate immune activity. Experiments have shown that injection of neural progenitor cells into the brain’s ventricles can modulate an immune response taking place at multiple inflammatory foci in a mouse model of multiple sclerosis, or at a single site at the injured spinal cord.
Higher transcription levels of Hh, along with other known associates of the Hh pathway, namely patched (Ptc) the Hh receptor, and cubitus interruptus (Ci), the Hh transcription factor is seen throughout the mid to late fifth instar as well, which further implies a role for Hh signaling in eyespot development and patterning. Furthermore, cells that are flanked by the cells expressing the highest level of Hh signaling are fated to become the foci, indicating that focus cell fate determination relies on high concentrations of Hh in surrounding cells. However this observation has not been totally confirmed as a rule for multiple butterfly species. Studies tried to extrapolate the result of Hh pathway involvement by looking for the expression of Ci in Bicyclus anynana.
Broadly speaking, magicians focus their magic outward, actively affecting the world around them, while adepts focus their magic inward, passively enhancing their bodies and minds. Magicians are able to cast spells, summon spirits, and create magical artifacts called "foci". All magicians follow traditions that determine their understanding of magic, including hermetic mages (whose control of magic comes through study and manipulation of magical energy or mana, and who summon and bind elementals in lengthy and expensive rituals to be called on later) and shamans (whose magic derives from a connection to nature via a totem spirit, and who can summon the nature spirits associated with a particular place). Adepts use magic internally in order to accentuate their natural physical abilities.
Recent creative advances and efforts in computing, such as semantic web, ontology engineering, knowledge engineering, and modern artificial intelligence provide philosophy with fertile ideas, new and evolving subject matters, methodologies, and models for philosophical inquiry. While computer science brings new opportunities and challenges to traditional philosophical studies, and changes the ways philosophers understand foundational concepts in philosophy, further major progress in computer science would only be feasible when philosophy provides sound foundations for areas such as bioinformatics, software engineering, knowledge engineering, and ontologies. Classical topics in philosophy, namely, mind, consciousness, experience, reasoning, knowledge, truth, morality and creativity are rapidly becoming common concerns and foci of investigation in computer science, e.g., in areas such as agent computing, software agents, and intelligent mobile agent technologies.
Heck served as Chief of the Coast and Geodetic Survey's Division of Seismology and Terrestrial Magnetism and was a leader in the development of geophysics, a field in which he had a broad range of interests. He made major contributions to seismology in his research on the energy consumed in the production of earthquakes, and he identified the foci of earthquake activity in mountain, coastal, and undersea areas.The Free Dictionary: Heck, Nicholas H. In the 1930s, he drew attention to a correlation between earthquake epicenters and the Mid-Atlantic Ridge, first publishing a world seismicity map showing seismic activity there in 1932.Robert, Christian M., Global Sedimentology of the Ocean: An Interplay Between Geodynamics and the Paleoenvironment, New York: Elsevier, 2009, , pp. 16-17.
Initially Farrar had been bonded to help Cicely Jordan, but they eventually married by 1625. Following the massacre, the original residence gradually expanded into the complex at the Jordan-Farrar site, a palisaded fortification structured around five English longhouses. This type of complex is similar to the fortified bawn used by the English to occupy and colonize Ulster during the same time period. The complex had two foci, the original two longhouses of the Jordan household and the three additional longhouses that were built after Farrar arrived; this unusual dual ground plan respected the social reality that Jordan's Journey at this time had two initially unmarried heads of household, William Farrar and Cecily Jordan, while still providing a systematic defensive arrangement based on the principles of then-current fortification theory.
At the time of the post, Bezos's lifetime spending on charitable causes was estimated to be $100 million. Multiple opinion columnists responded by asking Bezos to pay higher wages to Amazon warehouse workers. A year later in June, he tweeted that he would announce two philanthropic foci by the end of summer 2018. Bezos announced in September 2018 that he would commit approximately $2 billion to a fund to deal with American homelessness and establish a network of non-profit preschools for low income communities. As part of this announcement, he committed to establishing the "Day 1 Families Fund" to finance "night shelters and day care centers for homeless families" and the "Day 1 Academies Fund" for early childhood education. In January 2018, Bezos made a $33 million donation to TheDream.
Soda is an honest and sensitive young man who would like to be Kitani's friend and strives to reconstruct his story. The novel is told in the third person, but with two strong narrative foci on the two protagonists. Noma's novel is a denunciation of the corruption of the Japanese army during World War II, and it aims at providing "the readers with a true picture of what [Noma's] country was like when it was under the yoke of [militarism]" (from the author's preface). However, the depiction of the humiliating conditions in which Japanese soldiers were kept during the Second World War is not Noma's only purpose in writing Zone of Emptiness, as he "tried to describe not only the Japanese army but also what is universal in the Japanese soul".
Typhoid fever is caused by Salmonella serotypes which are strictly adapted to humans or higher primates—these include Salmonella Typhi, Paratyphi A, Paratyphi B, and Paratyphi C. In the systemic form of the disease, salmonellae pass through the lymphatic system of the intestine into the blood of the patients (typhoid form) and are carried to various organs (liver, spleen, kidneys) to form secondary foci (septic form). Endotoxins first act on the vascular and nervous apparatus, resulting in increased permeability and decreased tone of the vessels, upset of thermal regulation, and vomiting and diarrhoea. In severe forms of the disease, enough liquid and electrolytes are lost to upset the water-salt metabolism, decrease the circulating blood volume and arterial pressure, and cause hypovolemic shock. Septic shock may also develop.
Siemens staff stemmed from its various divisions, not just UBE (where the project unit was called E85G). The core development labs were located on an Intel site in Portland, OR, but there were also Siemens labs in Berlin, Germany, (Sietec Systemtechnik, Maxim Ehrlich's team creating the Gemini DBMS), Vienna, Austria, Princeton, New Jersey (United States) and also Nuremberg, Germany, involved in the development. Since neither Siemens nor Intel could see how to market this new architecture if it were broken up, in 1985 the project became BiiN Partners, and in July 1988 was launched as a company wholly owned by Intel and Siemens. A second company wholly owned by Intel, called BiiN Federal Systems, was also created in order to avoid Foreign Ownership and Controlling Interest (FOCI) problems in selling to the US government.
The conference resulted in Indo-Judaic Studies in the 21st Century, a book that was the focus of an academic panel at the 2008 annual meeting of the American Academy of Religion. Katz was selected as a delegate to the 1990 Tibetan-Jewish dialogue hosted by the Dalai Lama and reported in the best-selling The Jew in the Lotus. He reciprocated the hospitality in 1999 when the Dalai Lama first visited FIU for an honorary doctorate, as well as his 2004 and 2010 visits. Inspired by the Dalai Lama’s vision of educating both the “warm heart” and the “good brain,” Katz founded FIU’s innovative Program in the Study of Spirituality with foci on research, public programs and seminars, and the curriculum, including the world’s only undergraduate certificate in the study of spirituality.
Based on specialisation, MCom graduates are typically employed in fields related to their degree foci, such as financial services, marketing and project management; graduates also often work in general management and business consulting Programs are sometimes structured such that graduates are eligible for membership of various professional bodies or institutes. In some cases, the institutional qualification program itself may, in fact, be offered as an MCom degree (e.g. the Australian Institute of Public Accountants formerly offered its IPA program as an MCom in Public Accounting prior to July, 2017.) The MCom includes a research component and thus provides access to a doctorate; progressing from the MCom, a student can pursue a Doctor of Commerce (DCom), Doctor of Business Administration (DBA), or a Doctor of Philosophy (Ph.D) degree program.
Let P1, P2, ..., Pm be given as foci of a curve C of class m. Let P be the product of the tangential equations of these points and Q the product of the tangential equations of the circular points at infinity. Then all the lines which are common tangents to both P=0 and Q=0 are tangent to C. So, by the AF+BG theorem, the tangential equation of C has the form HP+KQ=0. Since C has class m, H must be a constant and K but have degree less than or equal to m−2. The case H=0 can be eliminated as degenerate, so the tangential equation of C can be written as P+fQ=0 where f is an arbitrary polynomial of degree m−2.
The criteria for an RIS diagnosis are as follows: #The presence of incidental MRI findings in the CNS white matter: ##Ovoid and well-circumscribed homogeneous foci, with or without involvement of the corpus callosum ##T2 hyperintensities larger than 3 mm in diameter, which fulfill at least 3 of the 4 Barkhof MRI criteria for DIS ##The CNS abnormalities are not consistent with a vascular condition #No historical accounts of clinical symptoms consistent with neurological dysfunction. #MRI anomalies do not account for apparent impairment in social, occupational, or generalized areas of functioning. #MRI anomalies are not due to substance abuse, such as recreational drug use, toxic exposure, or a prior known medical condition. #Exclusion of a differential diagnosis of leukoaraiosis, or extensive white matter pathology excluding the corpus callosum.
Anke Grotlüschen studied at the Wirtschaftsakademie Hamburg from 1988 – 1991 and finished as Betriebswirtin (Business Administration). She continued studying educational sciences from 1991 – 1997 with the main topics being Adult Education as well as psychology, sociology and politics as minors at the University of Hamburg. She finished this study program with a thesis about political education in the perspective of critical psychology. From 1998 – 2000 she worked as a coordinator in ESF- Programmes at the Berufsbildungswerk DGB GmbH (bfw) in Lübeck, until she became a research assistant at the University of Hamburg at the department of Education with the foci Adult Education and leisure research. She wrote her PhD in 2003 about learning resistance in E-Learning “Virtuell und selbstbestimmt? Widerständiges Lernen im Web” with Peter Faulstich as dissertation advisor.
While the greater part of the county was absolutely destitute of human life, and all the land northward lay blackened, Leeds in 1086 had a population of at least two hundred people. There were two significant foci to the settlement; the area around the parish church and the main manorial landholding half a mile to the west of the church. In 1399, according to the Hardynge Chronicle, the captive Richard II was briefly imprisoned at Leeds, before being transported to another de Lacy property at Pontefract, where he was later executed. :The kyng then sent kyng Richard to Ledis, :there to be kepte durely in previtee; :fro thens after to Pykering went he needis, :and to Knaresbro' after led was he :but to pontefrete last where he did dee.
During the 1980s, dentist Hal Huggins, sparking severe controversy, spawned biological dentistry, which claims that conventional tooth extraction routinely leaves within the tooth socket the periodontal ligament that often becomes gangrenous, then, forming a jawbone cavitation seeping infectious and toxic material. Sometimes forming elsewhere in bones after injury or ischemia,Leon Chaitow, Cranial Manipulation: Theory and Practice, 2nd edn (Edinburgh, London, New York, elsewhere: Elsevier, 2005), pp 348–49. jawbone cavitations are recognized as foci also in osteopathy and in alternative medicine,Examples: Ellen Hodgson Brown, Healing Joint Pain Naturally: Safe and Effective Ways to Treat Arthritis, Fibromyalgia, and Other Joint Diseases (New York: Broadway Books, 2001); Shirley MacLaine, Sage-ing While Age-ing (New York: Atria Books, 2007). but conventional dentists generally conclude them to be nonexistent.
A number of regional schools converged in the early Romanesque illuminated manuscript: the "Channel school" of England and Northern France was heavily influenced by late Anglo- Saxon art, whereas in Southern France the style depended more on Iberian influence, and in Germany and the Low Countries, Ottonian styles continued to develop, and also, along with Byzantine styles, influenced Italy. By the 12th century there had been reciprocal influences between all these, although naturally regional distinctiveness remained. The typical foci of Romanesque illumination were the Bible, where each book could be prefaced by a large historiated initial, and the Psalter, where major initials were similarly illuminated. In both cases more lavish examples might have cycles of scenes in fully illuminated pages, sometimes with several scenes per page, in compartments.
The university's "Doctoral Programme in Peace & Conflict Studies" commenced in fall of 2012. According to the website of the University for Peace, "this Doctoral Programme is designed to respond to a growing demand for academic and professional training that addresses the complex and multidimensional issues of peace and conflict in societies." The programme offers a broad range of research foci and specializations including, though not limited to, Environmental Security and Peace, Gender and Peace Building, International Law and Human Rights, International Law and the Settlement of Disputes, International Peace Studies, Media, Peace and Conflict Studies, Natural Resources and Peace, Peace Education, Responsible Management and Sustainable Development, and Sustainable Urban Governance and Peace. The programme offers two tracks for achieving the doctorate: a research track and a professional track.
Prior Editors in Chief include Iris Tabak, Josh Radinsky, Cindy Hmelo-Silver, Yasmin Kafai, and founding Editor Emeritus Janet Kolodner. JLS articles draw on theoretical frameworks from such diverse fields as cognitive science, sociocultural theory, educational psychology, computer science, and anthropology. Published articles are not limited to any particular research method, but are based on rigorous analyses that present new insights into how people learn and/or how learning can be supported and enhanced. They reflect the core practices and foci that have defined the learning sciences as a field: privileging design in methodology and pedagogy; emphasizing interdisciplinarity and methodological innovation; grounding research in real-world contexts; answering questions about learning process and mechanism, alongside outcomes; pursuing technological and pedagogical innovation; and maintaining a strong connection between research and practice.
Theorem 4 shows that with a centripetal force inversely proportional to the square of the radius vector, the time of revolution of a body in an elliptical orbit with a given major axis is the same as it would be for the body in a circular orbit with the same diameter as that major axis. (Proposition 15 in the Principia.) A scholium points out how this enables determining the planetary ellipses and the locations of their foci by indirect measurements. Problem 4 then explores, for the case of an inverse-square law of centripetal force, how to determine the orbital ellipse for a given starting position, speed, and direction of the orbiting body. Newton points out here, that if the speed is high enough, the orbit is no longer an ellipse, but is instead a parabola or hyperbola.
Cells infected by rotavirus (top) and uninfected cells (bottom) The focus forming assay (FFA) is a variation of the plaque assay, but instead of relying on cell lysis in order to detect plaque formation, the FFA employs immunostaining techniques using fluorescently labeled antibodies specific for a viral antigen to detect infected host cells and infectious virus particles before an actual plaque is formed. The FFA is particularly useful for quantifying classes of viruses that do not lyse the cell membranes, as these viruses would not be amenable to the plaque assay. Like the plaque assay, host cell monolayers are infected with various dilutions of the virus sample and allowed to incubate for a relatively brief incubation period (e.g., 24–72 hours) under a semisolid overlay medium that restricts the spread of infectious virus, creating localized clusters (foci) of infected cells.
This section starts on the southern side with Lignano Sabbiadoro, a resort city developed mainly after World War II. The Marano section goes until the "Palud de Soto" near Porto Buso and the island of Anfora, next to the mouth of the small river Aussa. The mooring complex (marina) of Lignano Sabbiadoro is the largest in Italy and among the largest in Europe, having more than 5,000 berths. The various structures of Aprilia Marittima, the harbour Marina Punta Faro, and the docks "Porto Vecchio" are strategically positioned around and near the southern areas of the Marano lagoon. The Nature Reserve of the Marano Lagoon stretches over more than 1,400 hectares, and it actually consists of two smaller reserves, the Reserve of the Stella River Mouth ("Riserva Foci dello Stella") and the Reserve of Canal Nuovo Valley ("Riserva Valle Canal Novo").
It explores the difference between detached reportage in its various foci: twenty men, a single bridge, a village; twenty villages; or one man, one bridge, one village, on one hand and immediate lived experience – the boots, the boards, the first white wall of the village rising through the first fruit trees on the other. Stevens' preference for immediate lived experience addressed in his scornful treatment of William Carlos Williams in "Nuances of a Theme by Williams", is what commentators have in mind when they speak of his sensualism. Magnifico may be one of those men crossing the bridge, shifting from viewing himself and the world from various external perspectives to the first-person viewpoint ("Of what was it I was thinking"?). What explicitly will not declare itself is subjective experience, and yet it declares itself through the action of the poem.
The first coins produced in East Anglia were minted during the reign of Ealdwulf. The issue and use of English coins during his reign followed its development in Kent, gold shillings or thrymsas produced during the 660670s, and thereafter, by a debasement linked to the diminishing gold quality of Frankish coin, with silver sceattas or pennies of various types. The distribution of findspots reveals foci of their use and possibly their issue at East Anglian centres of importance, especially in the north-west around Hunstanton, Bawsey in the Thetford area, the edge of the Fens around Isleworth and Exning, in the east around Burgh Castle, and in the area around Rendlesham, Ipswich and in the River Gipping valley. A map of the Anglo-Saxon kingdoms The status of coinage was not yet as a true currency, nor overtly regnal.
Since 2013 he has been a faculty member working on and creating teams that focus on a number of cutting-edge research foci: the Visuomotor Integration Laboratory (VMIL), focused on eye-hand coordination, as it relates to acquired brain injury (ABI), the REACTIV Laboratory (Rehabilitation Engineering Alliance and Center Transforming Low Vision), focuses on advanced wearables for the sensory deprived. His quest is to better understand how eye control intersects with hand control during eye-hand coordination after acquired brain injury (ABI) and what role vision and eye movements play in hand-focused motor recovery. As a secondary mission, he has and will continue to focus on leveraging technology in novel applications to better objectify accepted clinical measures, to assist in instrumenting the medical ecosystem to improve medical science, and to create innovative assistive technologies to help foster functional independence.
It appears that the state department for historic artefacts as well as the United States Coast Guard (USCG) and the Environmental Protection Agency (EPA) are not happy that "disposal" is the only course of action. The coast guard has the final sign off on the entire process and the understanding is that they are not happy for an unnecessary and dangerous step to be taken when there is an option to remove her safely on the table. The biggest fear is that the ship may sink in the narrow channel entrance or just outside the harbour; blocking Honolulu harbour for at least 6-12 months while a salvage operation takes place. FOCI have also been working with the support of the U.S. National Historic Maritime Society, seeking support from the National Park Service for their plans to repatriate her to Scotland.
SH BLF oscillations in boundary layer fluid along a flat plate must produce SH sound that reflects off the boundary perpendicular to the fluid laminae. In late transition, Schubauer and Skramstad found foci of amplification of BL oscillations, associated with bursts of noise (“turbulent spots”). Focal amplification of the transverse sound in late transition was associated with BL vortex formation. The focal amplified sound of turbulent spots along a flat plate with high energy oscillation of molecules perpendicularly through the laminae, might suddenly cause localized freezing of laminar slip. The sudden braking of “frozen” spots of fluid would transfer resistance to the high resistance at the boundary, and might explain the head-over-heels BL vortices of late transition. Osborne Reynolds described similar turbulent spots during transition in water flow in cylinders (“flashes of turbulence,” 1883).
The problems presented by the lignin and hemicellulose fractions are the foci of much contemporary research. A large sector of research into the exploitation of lignocellulosic biomass as a feedstock for bio-ethanol focuses particularly on the fungus Trichoderma reesei, known for its cellulolytic abilities. Multiple avenues are being explored including the design of an optimised cocktail of cellulases and hemicellulases isolated from T. reesei, as well as genetic-engineering-based strain improvement to allow the fungus to simply be placed in the presence of lignocellulosic biomass and break down the matter into D-glucose monomers. Strain improvement methods have led to strains capable of producing significantly more cellulases than the original QM6a isolate; certain industrial strains are known to produce up to 100g of cellulase per litre of fungus, thus allowing for maximal extraction of sugars from lignocellulosic biomass.
A Blaschke product is a certain kind of mapping of the unit disk in the complex plane to itself, and the ones considered in the first part of the book have order three (they map the unit circle three-to-one to itself, so that each point on the unit circle has three preimages). These triples of preimages form triangles that are all inscribed in the unit circle, and (it turns out) they all circumscribe an ellipse. Thus, they form an infinite system of polygons inscribed in and circumscribing two conics, as Poncelet's theorem describes. The ellipse is the boundary of the numerical range of a certain matrix derived from the Blaschke product, a region within which the eigenvalues of the matrix can be found, and in this case the eigenvalues are at the foci of the ellipse.
Modern forms of peace education relate to new scholarly explorations and applications of techniques used in peace education internationally, in plural communities and with individuals. Critical Peace Education (Bajaj 2008, 2015; Bajaj & Hantzopoulos 2016; Trifonas & Wright 2013) is an emancipatory pursuit that seeks to link education to the goals and foci of social justice disrupting inequality through critical pedagogy (Freire 2003). Critical peace education addresses the critique that peace education is imperial and impository mimicking the 'interventionism' of Western peacebuilding by foregrounding local practices and narratives into peace education (Salomon 2004; MacGinty & Richmond 2007; Golding 2017). The project of critical peace education includes conceiving of education as a space of transformation where students and teachers become change agents that recognise past and present experiences of inequity and bias and where schools become strategic sites for fostering emancipatory change.Salomon, G. (2004).
A hyperbola is the basis for solving multilateration problems, the task of locating a point from the differences in its distances to given points — or, equivalently, the difference in arrival times of synchronized signals between the point and the given points. Such problems are important in navigation, particularly on water; a ship can locate its position from the difference in arrival times of signals from a LORAN or GPS transmitters. Conversely, a homing beacon or any transmitter can be located by comparing the arrival times of its signals at two separate receiving stations; such techniques may be used to track objects and people. In particular, the set of possible positions of a point that has a distance difference of 2a from two given points is a hyperbola of vertex separation 2a whose foci are the two given points.
The most heavily studied aspect of neuroendocrine differentiation in prostate cancer (but not the only one, as mentioned above) is the focal type, which refers to a conventional prostatic adenocarcinoma that exhibits neuroendocrine foci at histopathological examination. Tumor xenografts of mice subjected to castration have been shown to undergo rapid regression with a dramatic drop in androgen receptor expression in tumor cells and a steep increase in the proportion of apoptotic cells Following castration, the proportion, as well as the density of neuroendocrine tumor cells, rises abruptly, eventually leading to the formation of neuroendocrine cell islets that are spread throughout the tumor and account for the majority of its constituent cells. The immunohistochemical phenotype of focal neuroendocrine differentiation in prostate cancer has been intensively studied. Chromogranin A, which is the most abundant product of prostatic neuroendocrine cells and neuroendocrine tumor cells, is widely recognized as a reliable marker for neuroendocrine differentiation.
Territories that have achieved a status described by the administering countries as internally self-governing – such as Puerto Rico, the Netherlands Antilles, and the Cook Islands – have been removed from the list by vote of the General Assembly, often under pressure of the administering countries. Some territories that have been annexed and incorporated into the legal framework of the controlling state (such as the overseas departments of France) are considered by the UN to have been decolonized, since they then no longer constitute "non-self-governing" entities; their populations are assumed to have agreed to merge with the former parent state. However, in 1961, the General Assembly voted to end this treatment for the "overseas provinces" of Portugal such as Angola and Mozambique, which were active foci of United Nations attention until they attained independence in the mid-1970s. Territories have also been removed for other reasons.
Most recently, CIC was asked to provide policy and research support to the Secretary-General's High- level Panel on Global Sustainability, with the Panel's findings expected to be released by the end of 2011.UN Secretary-General's High-level Panel on Global Sustainability In 2015, Sarah Cliffe, a former senior officer at the World Bank and the United Nations became CIC's third Director. CIC staff regularly collaborate with a number of international and domestic institutions, such as the Brookings Institution, the European Council on Foreign Relations, the Netherlands Institute for Multiparty Democracy (NIMD), the International Institute for Democracy and Electoral Assistance (IDEA), the Stanford University Center for International Security and Cooperation (CISAC), and Humanitarian Outcomes. CIC maintains strong links to the current U.S. Administration, strengthened through CIC's institutional and programmatic foci on issues of interest to the U.S. Government and to capitals around the world.
A point has a solid construction if it can be constructed using a straightedge, compass, and a (possibly hypothetical) conic drawing tool that can draw any conic with already constructed focus, directrix, and eccentricity. The same set of points can often be constructed using a smaller set of tools. For example, using a compass, straightedge, and a piece of paper on which we have the parabola y=x2 together with the points (0,0) and (1,0), one can construct any complex number that has a solid construction. Likewise, a tool that can draw any ellipse with already constructed foci and major axis (think two pins and a piece of string) is just as powerful.P. Hummel, "Solid constructions using ellipses", The Pi Mu Epsilon Journal, 11(8), 429 -- 435 (2003) The ancient Greeks knew that doubling the cube and trisecting an arbitrary angle both had solid constructions.
The network has existed in name since 1996 and in its early years, several critical Council meetings were held (in Brasília, Brazil, and in Miami, USA) which defined the general structure and proposed functions of IABIN. In the initial years however, no Secretariat existed and the network benefited only from a number of small ad hoc investments, primarily from the United States, the World Bank, and the OAS. In 2004, a major six-year investment began financed by the Global Environment Facility (GEF) (see below). Under this project, the network has developed its current foci of activities. These are the adoption of ecoinformatics standards and protocols, development of a catalogue and search tools (being done in coordination with NBII), creation of partnerships, creation and maintenance of the Secretariat, data creation grants, the operation of the “Thematic Networks”, and the creation of information tools for decision-makers.
A.G. Hogg, professor at Madras Christian College and author of Karma and Redemption in 1904, criticised Farquhar's "Fulfilment thesis" that says "Christianity fulfils all the noblest aspirations of the Hindus," as Hogg perceived that "in Hinduism there was searching and finding, and that a Christian was not offering what a Hindu was searching. Under certain circumstances, a Christian however could make the Hindu feel the need for what is available only in Christianity." Farquhar's Fulfillment School has also been discussed, with praise and / or censor, by many writers on philosophy or theology of religion, including Gavin D'Costa, Jacques Dupuis, John Hick, David Marshall, Ivan Satyavrata, James Sharpe, and James Thrower: Satyavrata and Sharpe provide extended analyses. Farquhar is often taken as a leading representative of the Inclusivist School, though this would be more plausible if the focus were on ontology and ethics, which are Farquhar's foci, rather than on salvation.
Kortun contributed to several books, including Fresh Cream: Contemporary Art in Culture (Phaidon Press, 2000), Foci: Interviews with 10 International Curators (ApexArt Curatorial Program, 2001), How Latitudes Become Forms: Art in the Global Age (Walker Art Center, 2003), and Signs Taken in Wonder: Searching for Contemporary Art about Istanbul (Hatje Cantz, 2013). In 2004, he co-authored the book Jahresring 51: Szene Turkei: Abseits aber Tor with Erden Kosova, focusing on the art scene in Turkey. In 2013, he co-edited VOTI Union of the Imaginary: A Curators Forum with Susan Hapgood and November Paynter, exploring the online discussion platform for international curators in the late 1990s. His texts have been included in numerous exhibition catalogues, such as the 2nd Johannesburg Biennial (1997), the 24th São Paulo Biennial (1998), Manifesta 2 (1998), and The United Arab Emirates Pavilion at the 54th International Art Exhibition, Venice Biennale (2011), among others.
As head of the Lyceum, Theophrastus continued Aristotle's foci of observation, collaborative research and documentation of philosophical history, thus making his own contributions to the library, most notably as the first organizer of botany. Though he was not a citizen of Athens (he had met Aristotle in the 340s in his homeland of Lesbos) he managed to buy land near the main gym of the Lyceum as well as several buildings for the library and additional workspace in . Theophrastus continued his own work while teaching and demonstrated his devotion to learning and education by leaving the land of the Lyceum to his friends to continue their work in education in philosophy in the non-private tradition of the school upon his death. During the era of Theophrastus and his successor, Strato of Lampsacus, the Lyceum experienced a decline until it fell with the rest of Athens in .
Changing theoretical perspectives have shifted the directions and foci of controversy but the differences in these orientations can largely be described in terms of the assumptions made about social organization. A continuing thread to the arguments has been disagreement over the nature of power relationships in Hohokam society and the importance of such relationships... Frank Midvale's Investigation of the Site of La Ciudad (1987) DOCUMENT [ID: 4405] David R. Wilcox. La Ciudad Phoenix was one of numerous Hohokam Indian villages that once were located about every three miles (4.8 kilometers) along extensive irrigation canals in the Salt and Gila river valleys. First founded in the early centuries A.D., La Ciudad endured for a millennium or more, evolving new forms of organization to meet life’s challenges on several scales of interaction, only to fail in the end when the Hohokam abandoned the Phoenix basin about A.D. 1450.
The stand was made by an employee of Tulley, James Smith, and is preserved in the Wellcome Institute. Smith set up on his own in 1837, later taking on Richard Beck, a nephew of Lister, as an apprentice finally becoming a partner in 1847 when the company was renamed Smith & Beck. Lister published his work in 1830 in a paper entitled "On Some Properties in Achromatic Object- Glasses Applicable to the Improvement of the Microscope" submitted to the Royal Society, and collaborated with Smith and with Andrew Ross, who had established what was to become one of the finest microscope manufacturers in 1832. Lister's law of aplanatic foci remained the underlying principle of microscopic science. He had a large circle of scientific contacts, including Airy, Herschel and fellow Quaker Dr Thomas Hodgkin, with whom he discussed microscopic observations including those of red blood cells, leading to the identification of 'Hodgkin's disease’.
Repair work was undertaken by WSW suspension railway workshop employees once extensive structural evaluations of overhead track support installation and of the effects wrought by the accident itself on the overhead track had been done by outside engineering consultants and other experts. Many safety tests were undertaken, among them a special inspection of the whole overhead track, including supports and test runs with the five articulated trains that since the accident had been the main and secondary foci of attention among the rolling stock. Extensive shunting work was necessary at the line's two termini, Vohwinkel and Oberbarmen to bring the trains into working order. Preparatory work for the repairs to the damaged parts of the overhead track at the accident site was begun on 31 May 1999, after the crane needed for replacing overhead track parts had been set up on ELBA's property a few days earlier.
Furthermore, Cahuachi's obvious influence and importance in Nasca society and the fact that it was primarily a ceremonial center suggests that political power and social differences may not have been exclusively based on the economy. This is further evidenced by a lack of clear mortuary differentiation in early Nasca society and iconographic portrayals of elites, which lead researchers to believe that there could have been at least a group- oriented chiefdom where accumulation of personal wealth was forgone or otherwise unachievable (Silverman 2002: 166). The main thing that connected the segments of peoples in the Rio Grande de Nazca drainage system were their Nasca cultural traditions and religious cult where Cahuachi was the center, but only as a temporary pilgrimage site, and otherwise they lived in their own smaller communities with their own separate local ceremonial and domestic foci, and was therefore not politically centralized. Nasca society in terms of its location in the Rio Grande de Nazca drainage system also played its part in their sociopolitics.
His specialties include computational optimization and algorithm design for logistics and manufacturing. He has participated in over 15,000 peer-reviewed publications in Spanish and English and has had his work published in journals such as IIE Transactions, Journal of Heuristics, Annals of OR, Computers and OR, Journal of Intelligent Manufacturing, EJOR, Transportation Science, Journal of the Operational Research Society, and Computers and Industrial Engineering. However, he began his academic career as a teacher and is still involved in this activity. From 1973 to 1985 he was a professor in mathematics at the Universidad Autónoma de Nuevo León, then worked as an assistant instructor with the Department of Mechanical Engineering of the University of Texas, Austin from 1985 to 1990. Since joining the Tec de Monterrey in 1990, his teaching foci include production, manufacturing and logistics systems, and computational optimization at the graduate level, supervising more than thirty master’s level theses and five doctorate level ones.
Rosa Martínez, in Carolee Thea, Foci: Interviews with ten international curator (Apex Art, New York, 2001): p.80 The curators altered the emphasis from a mere section into a "show within a show," featuring works by 120 artists including: Laura Aguilar, Matthew Barney, Henry Bond, Christine Borland, Maurizio Cattelan, John Currin, Sylvie Fleury, Dominique Gonzalez-Foerster, Felix Gonzalez-Torres, Lothar Hempel, Damien Hirst, Carsten Höller, Sean Landers, Paul McCarthy, Gabriel Orozco, Philippe Parreno, Simon Patterson, Charles Ray, Pipilotti Rist, Andres Serrano, Kiki Smith, Rudolf Stingel, Rirkrit Tiravanija, Andrea Zittel, Wu Shanzhuan, Wang Youshen, Emmanuel Kane Kuei and Botala Tala. Anticipating "the curators’ era," Aperto ’93 consisted of 13 sections, each of them managed by then-emerging curators, many of whom are now internationally acclaimed, such as Francesco Bonami (first Italian to curate the Whitney Biennial), Nicolas Bourriaud (theoretician of Relational Art), Jeffrey Deitch (director of the Museum of Contemporary Art, Los Angeles), Matthew Slotover (founder of Frieze magazine and art fair), Benjamin Weil and Robert Nickas.
The belief in green cover by early park proponents as a promoter of social cohesion has been corroborated by more recent research that links trees to the presence of stronger ties among neighbors, more adult supervision of children in outdoor areas, more use of the neighborhood common areas, and fewer property and violent crime (Kuo et al. 1998, Kuo and Sullivan 2001, Kuo 2003). Many municipalities throughout the United States employ community-level tree ordinances to empower planning officials to regulate the planting, maintenance, and preservation of trees. The development of tree ordinances emerged largely as a response to the Dutch Elm Disease that plagued cities from the 1930s to 1960s, and grew in response to urban development, loss of urban tree canopy, and rising public concern for the environment (Wolf 2003). The 1980s saw the beginning of the second generation of ordinances with higher standards and specific foci, as communities sought to create more environmentally pleasing harmony between new development and existing infrastructure.
Through courses like these, the Consortium could be thought of as developing an original conception of Cultural Studies. While the Centre for Contemporary Cultural Studies at Birmingham University—founded by Richard Hoggart and for a long time the institutional home of Stuart Hall—conceived of Cultural Studies as the study of contemporary popular culture, the London Consortium has sought to develop a research and teaching climate where the study of older historical periods, on the one hand, and of 'high' culture on the other, can take its place alongside the more traditional foci of the discipline. This also entails a different approach to interdisciplinarity. Where interdisciplinary studies had often been content to merely ignore the traditional academic disciplines, and run roughshod over disciplinary boundaries, the London Consortium preferred to describe its activities as multidisciplinary, reflecting the belief that while the best research benefited from being approached from two or more disciplinary perspectives, it must also stand up to the most exacting standards of the disciplines.
Aristotle's Rhetoric, renowned for its modes of persuasion in ethos, logos, and pathos, gave mankind its first recorded guide to and theory of social influence. Aristotle recognized that different appeals are necessary for different types of persuasion, and that these appeals can be tailored and refined to better suit the audience or better suit the product or idea at hand. In the late 1950s when psychoanalysis and behaviorism reigned supreme as the foci of psychological studies, Smith, Bruner, and White (1956) and Katz (1960) separately and independently developed typologies of human attitudes in relation to the functions to which they believed the attitudes served. The goal of these ‘functional attitude theories,’ (FAT) as they would come to be known, was to understand the effect of functional attitudinal states in relation cognition and behavior, and specifically, for Katz (1960),> to increase the efficacy of persuasive communications by matching approaches or appeals to the function that the attitude served.
In all cases, high-pressure fluid migration in the Earth's crust seems to be the trigger mechanism and the driving process that govern the evolution of the swarm in space and time. The Hochstaufen earthquake swarm in Bavaria, with 2-km-deep foci, is one of the rare examples where an indisputable relationship between seismic activity and precipitation could be established. Earthquake swarms raise issues from the point of view of public safety: first because the end of seismic activity cannot be ascertained; secondly because one can never be sure that another earthquake with a magnitude larger than those of previous shocks in the sequence will not occur. (The 2009 L'Aquila earthquake in Italy is emblematic, with an MW 6.3 shock following a swarm activity with magnitudes between 1 and 3.) Even though swarms usually generate moderate shocks, the persistence of felt earthquakes for a long time can be disruptive and cause distress to the population.
The results of numerous experimental and clinical studies of malignant neoplasms have indicated that invasive growth and metastasis are the main manifestations of tumor progression, which represent two closely related processes. A malignant tumor is characterized by the possibility to implement such a biological phenomenon as the metastatic cascade that is a unique multi-stage “program” where cell invasion is a trigger and a key factor for further cancer progression and metastasis in distant organs and tissues. Massive metastatic lesions lead to the development of severe organ failure and, therefore, a patient’s death. The range between “end” points of a complex invasive metastatic process –invasion of the primary tumor into surrounding tissues and the formation of metastatic foci –comprises several stages, the passage of which is strictly necessary for the successful development and subsequent progression of tumor growth: intravasation, survival and presence in the systemic circulation, extravasation with subsequent colonization of organs by tumor cells, and the formation of clinically detectable metastasis.
The origins of the Ovimbundu are Bantu populations who drifted in from the North, over the last millennium, and formed local/regional groups which slowly became political units and foci of social identity: M'Balundu, Sele, Wambo, Bieno and others. They developed a sophisticated agriculture, completed by the breeding of small animals (chicken, goats, swine) as well as of a modicum of cows bought from the farmer-herders to the South (Nyaneka-Nkhumbi, Ovambo). Incisive change came about when the Portuguese established a colonial bridgehead in Benguela, in the 16th century. Several of the small "kingdoms" saw their advantage in organising an intense caravan trade between Benguela and peoples of the East, in particular the Chokwe, the Luvale and the Mbunda,Terms of trade and terms of trust: the history and contexts of pre- colonial pages 403, 404 & 405...By Achim von Oppen, LIT Verlag Münster Publishers, 1993, from whom they obtained wax, rubber, honey and ivory.
Wolpoff was trained primarily as a paleoanthropologist at the University of Illinois under Eugene Giles. With his multidisciplinary training, he brings to the study of the human and non-human primate fossil record a background that combines evolutionary theory, population genetics, and biomechanics. With over 50 grants funded by the National Science Foundation, National Academy of Sciences, and the University of Michigan, Wolpoff has visited the museums where human and primate fossils are stored and has studied in detail and at length all the materials addressing the fossil evidence for human evolution across Europe, Asia, and Africa. His research foci have included the evolution and fate of the European Neandertals, the role of culture in early hominid evolution, the nature and explanation of allometry, robust australopithecine evolution, the distribution and explanation of sexual dimorphism, hominid origins, the pattern and explanation of Australasian hominid evolution, the contributions and role of genetics in paleoanthropological research, and the taxonomy of the genus Homo.
The bill would express the sense of Congress that the Voice of America (VOA): (1) has been an indispensable element of U.S. foreign policy and public diplomacy efforts and should remain the flagship brand of the Agency; and (2) would benefit from a recalibration of federal international broadcasting agencies and resources which would provide it with greater mission focus and flexibility. The bill would express the sense of Congress that RFE/RL, Incorporated, Radio Free Asia, and the Middle East Broadcasting Network share a common mission with distinct geographic foci, and should therefore be merged into a single organization with distinct marketing brands to provide news and related programming and content in countries where free media are not established. The bill would consolidate RFE/RL Incorporated, Radio Free Asia, and the Middle East Broadcasting Network into the (non-federal agency) Freedom News Network. The bill would state that RFE/RL, Incorporated, Radio Free Asia, and the Middle East Broadcasting Network shall remain brand names under which news and related programming and content may be disseminated by the Network.
Seizures rarely occur. Because atracurium undergoes Hofmann elimination as a primary route of chemodegradation, one of the major metabolites from this process is laudanosine, a tertiary amino alkaloid reported to be a modest CNS stimulant with epileptogenic activity and cardiovascular effects such a hypotension and bradycardia. As part of the then fierce marketing battle between the competing pharmaceutical companies (Burroughs Wellcome Co. and Organon, Inc.) with their respective products, erroneous information was quickly and subtly disseminated very shortly after the clinical introduction of atracurium that the clinical use of atracurium was likely to result in a terrible tragedy because of the significant clinical hazard by way of frank seizures induced by the laudanosine by-product \- the posited hypothesis being that the laudanosine produced from the chemodegradation of parent atracurium would cross the blood–brain barrier in sufficiently high enough concentrations that lead to epileptogenic foci. Fortunately, both for the public and for atracurium, rapid initial investigations irrefutably failed to find any overt or EEG evidence for a connection between atracurium administration and epileptogenic activity.
A 2009 study focusing on the naturally high background radiation region of Karunagappalli, India concluded: "our cancer incidence study, together with previously reported cancer mortality studies in the HBR area of Yangjiang, China, suggests it is unlikely that estimates of risk at low doses are substantially greater than currently believed." A 2011 meta-analysis further concluded that the "Total whole body radiation doses received over 70 years from the natural environment high background radiation areas in Kerala, India and Yanjiang, China are much smaller than [the non- tumour dose, "defined as the highest dose of radiation at which no statistically significant tumour increase was observed above the control level"] for the respective dose-rates in each district." In 2011 an in vitro time-lapse study of the cellular response to low doses of radiation showed a strongly non-linear response of certain cellular repair mechanisms called radiation-induced foci (RIF). The study found that low doses of radiation prompted higher rates of RIF formation than high doses, and that after low- dose exposure RIF continued to form after the radiation had ended.
Inbound ships, cargo and personnel require clearance by four main government bodies: China Customs for customs declaration, Border Inspection for migration formalities, China Inspection and Quarantine for quarantine and fumigation, and the MSA for ship and crew safety regulations. Obtaining clearance from these so-called “One Customs Three Inspections” (一关三检) used to be quite a protracted process, and one of the continued foci of Port reform is to speed up the clearance procedures and reduce their (still significant) burden. Customs Clearance: The custom agencies responsible for the Port are: the Tianjin Xingang Customs (天津新港海关), headquartered at the Container Logistics Center; the Tianjin Port Free Trade Zone Customs (天津港保税区海关), headquartered at the FTZ, and the Dongjiang Bonded Port Customs (东疆保税港区海关), headquartered at the Dongjiang Joint Inspection Center. All are subordinate units of Tianjin Customs (天津海关), which is responsible for the declaration, inspection, and duties collection for all international cargo, trade goods, luggage and postal items passing through the Port.
NETL helps advance development of technologies supporting efficient, environmentally benign unconventional domestic oil and gas resources. The Lab's research projects help catalyze the development of these new technologies, provide objective data to help quantify the environmental and safety risks of oil and gas development, and characterize emerging energy resources like methane hydrate or shale gas production. The program foci are on deepwater technology, enhanced oil recovery, and methane hydrate. NETL's research on unconventional oil and gas includes efforts for improving wellbore cement used to stabilize wells for deepwater drilling; expeditions to determine presence and volume of methane hydrate along coastlines; development of hydraulic fracturing data collection tools to improve environmental reporting, monitoring, and protection; analysis to determine alternate sources of freshwater for oil and gas development, as well as many other areas of expertise. Natural gas and oil resources supply two-thirds of the United States’ primary energy supply, and researching their development allows for their continued use as efforts toward transition to a more sustainable energy future are made.
A shelf cloud such as this one can be a sign that a squall is imminent Organized areas of thunderstorm activity not only reinforce pre-existing frontal zones, but can outrun cold fronts in a pattern where the upper level jet splits apart into two streams, with the resultant Mesoscale Convective System (MCS) forming at the point of the upper level split in the wind pattern running southeast into the warm sector parallel to low-level thickness lines. When the convection is strong and linear or curved, the MCS is called a squall line, with the feature placed at the leading edge of the significant wind shift and pressure rise. Even weaker and less organized areas of thunderstorms lead to locally cooler air and higher pressures, and outflow boundaries exist ahead of this type of activity, which can act as foci for additional thunderstorm activity later in the day. These features are often depicted in the warm season across the United States on surface analyses and lie within surface troughs.
Though nuclear import of TPX2 is thought to sequester TPX2 away from cytoplasmic tubulin in order to solely prevent premature spindle assembly, roles of nuclear TPX2 have recently been discovered. One of these roles is with the DNA damage response, where depletion of TPX2 in cells leads to a transient increase in γ-H2AX (the phosphorylated form of H2AX, the form that serves as a marker of DNA damage response amplification) levels in cells treated with ionizing radiation, and overexpression of TPX2 leads to a decrease in the number of ionizing radiation-induced MDC1 foci and γ-H2AX levels. This is supported by the discovery of TPX2 accumulation at DNA double strand breaks and association with the machinery of DNA damage response that controls the amplification of γ-H2AX. However, the exact molecular mechanisms by which TPX2 impacts the ionizing radiation-dependent γ-H2AX levels still remains to be discovered. Note that TPX2’s function in the DNA damage response is independent of its mitotic function, and is therefore independent of apoptosis.
Bioinformatics approaches support the idea that, by these properties, S/MARs not only separate a given transcriptional unit (chromatin domain) from its neighbors, but also provide platforms for the assembly of factors enabling transcriptional events within a given domain. An increased propensity to separate the DNA strands (the so- called 'stress induced duplex destabilization' potential, SIDD) can serve the formation of secondary structures such as cruciforms or slippage structures, which are recognizable features for a number of enzymes (DNAses, topoisomerases, poly(ADP-ribosyl) polymerases and enzymes of the histone- acetylation and DNA-methylation apparatus). S/MARs have been classified as either being constitutive (acting as permanent domain boundaries in all cell types) or facultative (cell type- and activity-related) depending on their dynamic properties. While the number of S/MARs in the human genome has been estimated to approach 64,000 (chromatin domains) plus an additional 10,000 (replication foci), in 2007 still only a minor fraction (559 for all eukaryotes) had met the standard criteria for an annotation in the S/MARt database SMARtDB.
Despite a higher incidence of breast cancer amongst those taking orlistat in early, pooled clinical trial data—the analysis of which delayed FDA review of orlistat—a two-year study published in 1999 found similar rates between orlistat and placebo (0.54% versus 0.51%), and evidence that tumors predated treatment in 3 of the 4 participants who had them. There is evidence from an in vitro study to suggest that the introduction of specific varied preparations containing orlistat, namely the concurrent administration of orlistat and the monoclonal antibody trastuzumab, can induce cell death in breast cancer cells and block their growth. Fecal fat excretion promotes colon carcinogenesis. In 2006 the results of 30-day study were published indicating that orlistat at a dosage of 200 mg/kg chow administered to rats consuming a high-fat chow and receiving two 25 mg/kg doses of the potent carcinogen 1,2-dimethylhydrazine produced significantly higher numbers of aberrant crypt foci (ACF) colon lesions than did the carcinogen plus high-fat chow without orlistat.
Various studies have compared the predictive performance of PI-RADS v1 for detecting significant prostate cancer against either image-guided biopsy results (definitive pathology) and/or prostatectomy specimens (histopathology). In a 2015 articles in the Journal of Urology, Thompson reported multi-parametric MRI detection of significant prostate cancer had sensitivity of 96%, specificity of 36%, negative predictive value and positive predictive values of 92% and 52%; when PI-RADS was incorporated into a multivariate analysis (PSA, digital rectal exam, prostate volume, patient age) the area under the curve (AUC) improved from 0.776 to 0.879, p<0.001. A similar paper in European Radiology found that when correlated with histopathology, PI-RADS v2 correctly identified 94-95% of prostate cancer foci ≥0.5 mL, but was limited for the assessment of GS ≥4+3 (significant) tumors ≤0.5 mL; in their series, DCE-MRI offered limited added value to T2WI+DW-MRI. Other applications for which PI-RADS may be useful include prediction of termination of Active Surveillance due to tumor progression/aggressiveness, detection of extraprostatic extension of prostate cancer, and supplemental information when considering whether to re-biopsy patients with a history of previous negative biopsy.
Haïdar-Boustani, Maya., Neo-lithics 01/07 - 2007 The geography and geomorphology of this alluvial filled, tectonic depression has been explored as part of a wider investigation of the area by various research bodies. The foci of this study has been archaeological and palaeoenvironmental evolution of the central Levant region.Haïdar-Boustani, Maya., PROSPECTIONS ARCHÉOLOGIQUES À L'OUEST DE LA VILLE DE HOMS ..., d'Histoire et d'Archéologie, Université Saint-Joseph, Beyrouth The survey project commenced in 2004 as a partnership of the Museum of Lebanese Prehistory, Directorate General of Antiquities and Museums in Syria, the Mila and Fontanals Institution of the Higher Council for Scientific Research (Barcelona) and the International Institute for Prehistoric Research in the University of Cantabria (Santander). Scientific direction was carried out jointly by Dr. Michel Al-Maqdisi (Directorate of Antiquities and Museums of Syria), Dr. Maya Haïdar Boustani (Museum Lebanese Prehistory, LSU) and Dr. Juan José Ibañez (Mila and Fontanals Institution).Museum of Lebanese Prehistory Website - Recherches au SyrieJJ Ibáñez, M Haidar-Boustani, M al Maqdissi…, La ocupación prehistórica al oeste de Homs (Siria) Studies of the late pleistocene and early holocene sedimentary record of the besin has defined a stratigraphical framework for further studies of the area.
Ben- Jacob's studies in neuroscience are guided by an effort to simplify the complexity searching for principles of information coding, memory and learning. He has many unique contributions in the field of Systems Neuroscience and Neural Networks, including the relations between network size and its synchronized activity, the discovery of hidden neuron correlations, function-form relations and mutual synchronization in engineered networks, the effect of DNA damage on network synchronization, neuro-glia communication, new modeling of intra- and inter-cell calcium dynamics, using nano technology for network engineering, discovery and modeling of the dynamical motives (repertoire) of coupled neural networks, development of a novel system-level analysis of neural network activity (the functional holography analysis), mapping and assessments of epileptic foci, and more. Yet, the development of the first neuro-memory-chip with his doctoral student at the time, Itay Baruchi, is Ben-Jacob's most important contribution in systems neuroscience. While previous attempts were based on "teaching by reward" (enhancing excitatory synapses) or "teaching by punishment" (inhibition of excitatory synapses), Baruchi and Ben-Jacob's approach was "teaching by liberation", or "inhibition of inhibition" (inhibition of inhibitory synapses).

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