"(The demonstrators) accuse the police of being indolent," Mende said.
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He also keeps a sharp lookout for thieves, delinquents and indolent workers.
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We lolled over the papers in the morning, hung over and indolent.
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And at the epicenter of the country's violent upheaval is the indolent cow.
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Indolent aristocratic landowners can't compete with yeoman farmers without laws preventing land sales.
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Bicol Express is another classic, pork grown indolent in coconut milk and needled by chiles.
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Criticising his application demands nothing more than consultation with your thesaurus. Indolent. Lethargic. Lackadaisical. Languid. Uninterested.
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This is the laziest old-fashioned I know, and I drink it with immense, indolent pleasure.
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It's deceptively crystalline, belying its lushness, and almost indolent in how it clings to the tongue.
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Perhaps my wife won't like London; then the sentence is banishment and degradation into indolent, idle fool.
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"It's still too hot for Krakow and there's so much August left," an indolent Polish heir complains.
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There's no need to stay silent before the Menstruhaters of the world or do the job for indolent Slackhusters.
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Indolent and apparently untroubled by his multiple failings, Antonio had received the farm as part of his wife's dowry.
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In fact, many people harbor indolent forms of cancer that do not actually pose a risk to their health.
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From his indolent delivery to his slouch (he can't bother to sit up), he comes off as supremely self-absorbed.
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Barren is the indolent son of a great scientist in a flying car-filled, there's-my-jetpack version of 2016.
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Mr. Guadagnino is very good at catching the indolent drift of long summer days, with their sleepiness and bared limbs.
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On its own, the broth is almost indolent, flavor and texture inseparable; you taste plushness, and it lasts and lasts.
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To even severer critics, he appears to have remained cheerfully indolent, almost willfully failing to fulfill the remarkable early promise.
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We see our virtues and vices reflected in animals — hardworking beavers, indolent sloths, innocent lambs, greedy vultures — through a glass darkly.
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The incursion of technology into every aspect of consumption has meant that only the indolent or pathologically tolerant wait for things.
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Over half of men age 60 and older have small, indolent, nonlethal prostate cancers — many more than those who have harmful ones.
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But it raised a tantalizing question: How could the hunting, foraging Hadza possibly burn the same amount of energy as indolent Westerners?
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The ugly welfare stereotypes that Hannity advances -- an indolent African-American, a long-haired California hippy -- feed the grievances of his audience.
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But Jessup, a small-town Vermont newspaper editor and a "mild, rather indolent and somewhat sentimental liberal," worries about the devastation ahead.
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From the dock, just weave between indolent sea lions and impassive ruby-red marine iguanas and ask around for the truck to the highlands.
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They recall John Ashbery's collages, with their implication of the self as the center of an indolent cosmos of pop trash and fine art.
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Furthermore, indolent lymphomas typically progress slowly, so the quality and duration of the responses even from the limited responders will need to be assessed.
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In a dark bedroom with an indolent cat, she wakes reluctantly in the house she shares with her parents (Fiona Shaw and Robert Pugh).
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So last fall, he rapidly turned disaster response into a culture war food fight, pitting heroic first responders against indolent Puerto Rican political officials.
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In one realm, the indolent king preferred sycophants to tell him that his kingdom was thriving, though it was under constant threat from invaders.
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The disease can be indolent, which spreads slowly with few signs and symptoms, or aggressive, which spreads quickly with severe symptoms, the institute said.
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This research also revealed that even though Ju/'hoansi did not have to work particularly hard, they were neither indolent nor bereft of purpose.
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Based on a short story by Jack Ritchie, "A New Leaf" stars Matthau as Henry Graham, an indolent playboy who's burned through his fortune.
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Like him, his memoir has an affable, indolent, Whiggish air, which might have made him an adequate if forgettable prime minister in the eighteenth century.
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If Mr. Cummings's plan is to divide the Conservative Party from the inside out, Boris Johnson is his co-conspirator as his careless, indolent host.
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In a time of war, the obnoxious, indolent King Peiliang (Zheng Kai) is content to let a vital city remain in the hands of the enemy.
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"People who exercise generally go in for more checkups" than sedentary people, he said, resulting in more screenings for conditions such as so-called indolent prostate cancers.
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Perverse racial logic then attached the watermelon to newly freed people, who built a nation in bondage but were slandered as indolent loafers after the Civil War.
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Mr Macron is desperate to dispel suspicions in Germany that he wants a "transfer union" in which prudent northern European taxpayers are shaken down to subsidise the indolent elsewhere.
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There's even one called (shoot me now) "BFF" (by the Plain White T's), performed by SpongeBob and his bestie, the indolent starfish Patrick Star (a very good Danny Skinner).
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The rich today are no longer an indolent "leisure class" but what Markovits calls a "superordinate" working class: they work harder, longer, and perform more high-skilled work than ever before.
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In the 1920s, steely capitalists worried that such indolent fat cats would undermine entrepreneurship while fiery radicals ridiculed their only work as picking up a ticket at the opera box office.
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One widely read essay in National Review went so far as to label the troubled Eastern Heartland "the white ghetto," whose people are too indolent to move to where the jobs are.
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Among men with an elevated PSA who are found on biopsy to have cancer, about 80 percent have an indolent form of the disease that is highly unlikely to become life-threatening.
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Why it matters: Indolent non-Hodgkin's lymphomas (iNHLs) tend to be a slow-growing cancer that is incurable with standard therapy and poorly responsive to a newer type of treatment called checkpoint blockade.
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Duvelisib also met the main goal in a trial testing the drug as a treatment for indolent non-Hodgkin's lymphoma, a slow-progressing cancer of the blood cells, Needham, Massachusetts-based Verastem said.
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" As Gene Demby perfectly summed up on NPR in 2013: "In the popular imagination, the stereotype of the 'welfare queen' is thoroughly raced — she's an indolent black woman, living off the largess of taxpayers.
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But while it can be aggressive and fatal in some, many men with an indolent form of the disease never experience symptoms and would not even know they had it if not for screening.
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She starred opposite Alain Delon as an indolent rich girl living in Italy, later played by Gwyneth Paltrow in "The Talented Mr. Ripley," the 1999 American film, starring Matt Damon, based on the same novel.
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But like a fairy-tale princess, he is just as quickly rescued by Émile (Quentin Dolmaire) and Caroline (Louise Chevillotte), indolent beauties with sensuous mouths and impassive gazes that, lizardlike, flicker to life on seeing Yoav.
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The only work with real color is Max Beckmann's 1934 painting, "Ali With Mask," which portrays an indolent odalisque whose black mask makes her seem all but blinded — like the museum, Ms. Weems seems to say.
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Yet when a biopsy after an elevated PSA reveals cancer, even a cancer considered indolent, it can provoke considerable anxiety, and some men may choose to undergo unnecessary treatment that can cause impotence, incontinence or both.
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On these fields built for polo, that obsolete sport of the wealthy and indolent, I stood next to four blonde girls with designer sunglasses, enough concealer and glitter to disregard Kendrick's "No Make Up," and skirts as small as scarves.
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This approach results in the diagnosis of many fewer indolent cancers that would likely never threaten a man's life, said Dr. Klotz, a professor of surgery at the University of Toronto and a mentor in the field of prostate cancer diagnosis.
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They get the job done — delivering a mildly enjoyable movie that committed fans of the franchise will rate a lot higher — but they have to hack through a lot of by-the-numbers plotting and indolent characterizations to get there.
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They get the job done — delivering a mildly enjoyable movie that committed fans of the franchise will rate a lot higher — but they have to hack through a lot of by-the-numbers plotting and indolent characterizations to get there.
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He chronicled his excruciating treatment in a sketchbook that he then turned into an artist book titled Relatively Indolent But Relentless, a phrase his doctor had used to describe the cancer, but which Freedman felt was also an accurate description for himself.
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That remains Coppola's finest hour, and, by her standards, the new work is amazingly unhip—touched with a gruesomeness that makes you giggle ("Go to the smokehouse and get me the saw, now "), yet too indolent to summon the energy for camp.
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San Francisco may have become generally indolent, but those closest to its history remain rooted in the populist action that made the city a beacon for all kinds of people marginalized and alienated by mainstream society, including LGBTQ populations, immigrants, and radicals.
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The first patient, who joined the study in February 2017 and was treated at the National Institutes of Health, had an indolent form called "smoldering," and had survived, with various treatments, for more than 20 years, according to Dr. Thomas A. Waldmann, a physician and scientist there.
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And it doesn't hurt that the film boasts what is likely the best cast version of the story; it's difficult to imagine anyone better than Chalamet for indolent, lovable Laurie; a more believably ambitious and vivacious Jo than Ronan; or a better, finer Aunt March than Streep.
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Casting himself as a champion of the young, Prince Muhammad (known as MBS) understands that his country must reinvent itself to deal with the end of the oil boom, a burgeoning and indolent population, and a puritanical Wahhabi religious ideology that has been a Petri dish for jihadism.
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In the similarly alone-together diptych "Summer Afternoons" (7413), a younger man and woman, naked and indolent, occupy separate shots of a colorful living room — one with raking light redolent of Edward Hopper's interiors, and yellow walls and fuchsia velvet upholstery modeled on Mr. Wall's own graduate-school housing.
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There are animals, too, gamboling in the park — the indolent elephant with a parasol, the raffish bunny in a boater, a family of giraffes — all of it a gloss on the uptown social scene, whimsical, charming, with a tiny spritz of irony, like the Vermouth in your gin.
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The lack of perceivable symptoms coupled with most people's indolent attitude toward their own sexual health means it's probably just a matter of time before I do get it, and on that day I will have to look Ice Cube OB/GYN in the face and it will not be a good day.
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By testing samples of blood and urine or analyzing the genetic makeup of prostate cells for changes in their DNA, urologists are trying to more accurately determine not only if men have prostate cancer but also if those diagnosed have aggressive cancer that calls for further treatment or indolent, low-grade prostate cancer that poses very little risk.
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"All of these tests are focused on helping us pick out who has indolent cancer that we can keep an eye on and who has aggressive cancer and can risk the side effects from treatment and surgery," said Phillip M. Pierorazio, urologist and faculty member at the James Buchanan Brady Urological Institute at Johns Hopkins Hospital.
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Shay mentions to Romolo, the Italian proprietor of the Fleur des Îles, that she wants to talk to Harena, and, sure enough, early the next afternoon she catches sight of the girl making her way down the beach toward the Red House, in the indolent manner of a cat that has just decided to roam in that direction.
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In the futuristic world of "The Hunger Games," first magicked up by the author Suzanne Collins but taken to a new level in the movie, 22 largely impoverished and exploited colonies are ruled by the Capitol: a society so indolent and pampered that its denizens have had their souls corrupted by the pursuit of … plastic surgery!
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From the scent itself — a fresh, airy fragrance that recalls a zesty springtime breeze rather than heady, indolent old-lady rose — and the inspiration behind it down to the limited-edition packaging and the fact that it's a $48 bottle of hair perfume, for crying out loud, everything about the luxe Parisian brand's latest offering is opulent to the very last detail.
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The cause of indolent lymphoma is still unknown, however research has identified a number of factors that increase the risk of developing indolent lymphoma.
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She was young, portionless, bad with money, indecisive, and indolent.
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Carbonnell et al. first described a case of an indolent GI tract lymphoproliferation disorder in 1994 and defined the lymphocytes involved in it to be T cells expressing the CD4 glycoprotein on their surface membranes. Subsequent studies reported on patients who had a similar indolent GI tract disorder that involved T cells which expressed either the CD4, CD8, or neither surface membrane glycoprotein. The disorder resembled certain aggressive GI tract lymphomas and was variably termed indolent lymphoma or indolent T cell lymphoproliferative disorder of the gastrointestinal tract.
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Indolent lymphomas encompasses a heterogeneous group of non-Hodgkin Lymphomas (NHL) that are slowly progressive. Except for a few exceptions, indolent lymphomas are almost entirely of B cell origin. They are classified based on pathological and cytological features. Types of indolent lymphomas include follicular lymphoma, marginal zone lymphoma, lymphoplasmacytic lymphoma, small cell lymphocytic lymhoma/chronic lymphocytic leukemia, and hairy cell leukemia.
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The indolent habits, the unnamable tastes, have demoralized and unmothered the creature.
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Such patients have fever as the manifestation of infection, inflammatory responses are indolent.
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It was aristocratic, enchantingly indolent, like the face of a happy lotus-eater.
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People infected with human immunodeficiency virus (HIV) are at a slightly higher risk of developing indolent lymphoma than the general population. For patients who were previously diagnosed with an AID- defining illness, the risk of developing indolent lymphoma is 14-fold higher.
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Indolent lymphoma, also known as low-grade lymphoma, is a group of slow growing non-Hodgkin Lymphoma (NHL). Because indolent lymphoma is usually very slow growing and slow to spread, it tends to have fewer signs and symptoms when first diagnosed and may not require treatment straight away. Possible symptoms include one or more swollen but painless lymph nodes, unexplained fever and unintended weight loss. There are several subtypes of indolent lymphoma.
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It would be quite difficult to eradicate the indolent, careless, incogitant habits so formed in youth.
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Indolent lymphoma tends to grow slowly. As a result, patients with indolent lymphoma may not need to start treatment upon diagnosis. Patients are closely monitored and treatment usually starts when the disease progresses and causes symptoms. This is called the "wait and watch" approach or "watchful waiting".
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Although ASPS displays a relatively indolent course, the ultimate prognosis is poor and is often characterized by late metastases.
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Follicular lymphoma (FL) is a type of B cell lymphoproliferative disorder and is generally associated with an indolent course. It originates from the follicular center B cells. About 85% of the cases show t(14;18)(q32;q21) chromosomal translocation, which causes the overexpression of the anti- apoptotic protein BCL-2. FL is the most prevalent form of indolent lymphoma, accounts for 70% of indolent cases and 20~30% of all NHL cases, with an incidence of 1.6 to 3.1 per 100 000 persons/year.
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Whig and Tory is a 1720 comedy play by the British writer and actor Benjamin Griffin. Griffin himself starred as Sir John Indolent with Mrs Gulick as Charlotte.Highfill, Burnim & Langhans p.366 & 450 John Harper played Sir Roland Heartfree, Christopher Bullock was Ned Indolent, Lacy Ryan was Reynard and William Bullock was Coblecause.
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Treatment includes radiation and chemotherapy. Early-stage indolent B-cell lymphomas can often be treated with radiation alone, with long-term non-recurrence. Early-stage aggressive disease is treated with chemotherapy and often radiation, with a 70-90% cure rate. Late- stage indolent lymphomas are sometimes left untreated and monitored until they progress.
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The process may be initially indolent, making regular screening for diabetic nephropathy in patients with diabetes mellitus of great importance.
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This they could do with perfect impunity, as they had poisoned the mind of the indolent and suspicious king against their victim.
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Phase II clinical trials are in progress for treatment of endometrial cancer, diffuse large B-cell lymphoma, cholangiocarcinoma, and non-Hodgkin lymphoma. Copanlisib in combination with R-CHOP or R-B (rituximab and bendamustine) is in a phase III trial for relapsed indolent non-Hodgkin lymphoma (NHL). Two separate phase III trials are investigating the use of copanlisib in combination with rituximab for indolent NHL and the other using copanlisib alone in cases of rituximab-refractory indolent NHL. In a preclinical study, copanlisib was effective in inhibiting HER2+ breast cancer cells with acquired resistance to the HER2-inhibitors trastuzumab and/or lapatinib.
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In one study, the 10-year tumor free survival rate for sacral chordoma was 46%. Chondroid chordomas appear to have a more indolent clinical course.
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All this disproves the notion that Filipinos are by nature indolent. Rizal ends by asking what then would have caused Filipinos to forget their past.
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One combination for stage III/IV relapsed or refractory indolent lymphomas and mantle cell lymphoma (MCL), with or without prior rituximab-containing chemoimmunotherapy treatment, is bendamustine with mitoxantrone and rituximab. In Germany in 2012 it has become the first line treatment of choice for indolent lymphoma.New Combo Replaces CHOP for Lymphoma. Dec 2012 After trial results released in June 2012 showed that it more than doubled disease progression-free survival when given along with rituximab.
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Manitoba Legislative building On the north side of the Legislative Building, above the 6 main columns, is the main pediment."The Exterior", at the Legislative Tour, Province of Manitoba. In the bottom-left corner of the pediment is the Indolent Man, with a half-kneeling woman, the spirit of progress, beckoning the Indolent Man into the new land of promise. Next is the goddess Europa leading a bull, symbolizing Canada's European heritage and immigration.
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In 1781, she married count Paul Martynovich Skavronsky, who died 1791. In 1798, she married for love to count Giulio Renato Litta. She was described as kind, passive and indolent.
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Phosphatidylinositol 3-kinase (PI3K) inhibitors such as copanlisib, idelalisib, or duvelisib may be used to treat relapsed indolent lymphoma. Combination immunotherapy with lenalidomide and rituximab. Radiolabeled monoclonal antibody therapy. Clinical trials.
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Many low-grade lymphomas remain indolent (growing slowly or not at all) for many years – sometimes, for the rest of the person's life. With an indolent lymphoma, such as follicular lymphoma, watchful waiting is often the initial course of action, because monitoring is less risky and less harmful than early treatment. If a low-grade lymphoma becomes symptomatic, radiotherapy or chemotherapy are the treatments of choice. Although these treatments do not permanently cure the lymphoma, they can alleviate the symptoms, particularly painful lymphadenopathy.
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Patients with indolent systemic mastocytosis have a normal life expectancy. The prognosis for patients with advanced systemic mastocytosis differs depending on type of disease with MCL being the most serious form with short survival.
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Smart is the debut studio album by English Britpop band Sleeper, released on 14 March 1995 by Indolent Records. It was mixed by Stephen Street. The album's sleeve photo is of the Mercury Seven astronauts.
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The risk of developing indolent lymphoma increases with age. Although the disease can occur at any age, it mainly affects older adults. It is uncommon in people under age 40 and very rare in children.
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Brother and father were indolent. She helped run the family. One big sister Padma (Yokini) worked in the shop, while sisters Priya (Kaviya) and Revathy (Dhanalakshmi) studied in college. Kaveri loved and married Karthick (Rishikesh).
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They are typically divided into low and high grade, typically corresponding to indolent (slow-growing) lymphomas and aggressive lymphomas, respectively. As a generalisation, indolent lymphomas respond to treatment and are kept under control (in remission) with long-term survival of many years, but are not cured. Aggressive lymphomas usually require intensive treatments, with some having a good prospect for a permanent cure.Merck Manual home edition, Non-Hodgkin Lymphomas Prognosis and treatment depends on the specific type of lymphoma as well as the stage and grade.
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While the disease almost always has a highly indolent course, it is subject to repeated relapses that are usually limited to the skin. Rarely, primary cutaneous EMZL disseminates to other tissues and becomes a systemic disease. Treatment of primary cutaneous EMZL has been conservative, given the diseases indolent behavior. In Borrelia burdorferi-positive disease, antibiotic therapy (courses of a cephalosporin or tetracycline are regarded as first-line antibiotic choices) should be considered although this measure is less applicable in areas, such as the United States, where the bacterium has not been associated with the disease.
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Treatment will be started if the patients have too many cancer cells in their body, even if there are no symptoms.The treatment for indolent lymphoma is highly individual depending on a range of factors including the subtype of the disease, its stage, the patient's age and other medical conditions. Patients with early stage indolent lymphoma may be cured with radiation therapy alone, but most patients have widespread disease at the time of diagnosis. There are many effective treatments to control these stages of disease, but they are not reliably curative.
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Indolent T cell lymphoproliferative disorder of the gastrointestinal tract or Indolent T cell lymphoproliferative disorder of the GI tract (ITCLD-GT) is a rare and recently recognized disorder in which mature T cell lymphocytes accumulation abnormally in the gastrointestinal tract (GI tract). This accumulation causes various lesions (e.g. polyps, thickened mucosal folds, small areas of redness, and superficial ulcerations) in the mucosal layer lining the GI tract. Individuals with ITCLD-GT commonly complain of chronic GI tract symptoms such as nausea, vomiting, diarrhea, abdominal pain, and rectal bleeding.
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In October 2008, the FDA granted further approval to market Treanda for the treatment of indolent B-cell non-Hodgkin's lymphoma that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.
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Snyder claimed the men, "never spoke of malice of Lincoln but always in a spirit of ridicule" and that they characterized Lincoln as "indolent and vulgar", "a joke, an absurdity", and the men "had serious doubts about his courage".
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Indolent Records was a British record label set up in 1993 as a subsidiary of RCA Records and BMG. The label roster included Sleeper, The Wannadies, Stephen Duffy and 60ft Dolls. The label was folded into RCA Records in 1998.
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Chronic stimulation of the lymphocytes at the cytokine level may play a role in the development of the malignancy. The lymphoma ranges from a very indolent and slowly progressive type to a very aggressive and nearly uniformly lethal proliferative type.
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Lead time bias is the concept that early diagnosis may artificially inflate the survival statistics of a cancer, without really improving the natural history of the disease. Length bias is the concept that slower growing, more indolent tumors are more likely to be diagnosed by screening tests, but improvements in diagnosing more cases of indolent cancer may not translate into better patient outcomes after the implementation of screening programs. A related concern is overdiagnosis, the tendency of screening tests to diagnose diseases that may not actually impact the patient's longevity. This problem especially applies to prostate cancer and PSA screening.
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Harriet Farrington arrives to take charge at a small, unimportant British Consulate. She is horrified to find out how indolent and scheming her staff are, and - with more than a hint of Margaret Thatcher about her mannerisms - sets out turn the Consulate around.
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It tells of the indolent afterlife of Belacqua, trying to sit in a fetal position as much as possible, and being interrupted by visitors. In later fiction, Beckett would sometimes refer to Dante's Belacqua. The title character of Murphy has a Belacqua fantasy.
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Butler 2013, p. 93. He went on to study at Christ Church, Oxford, but was too indolent to flourish, and graduated with a third class degree in Classics.Veysey 1981–2, pp. 153–4. In 1839 his sister Catherine married William Ewart Gladstone.
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As an implausibly idealistic loss adjustor, he is disgusted by the company's scams to avoid pay-outs. He fiddles the claims in favour of the claimants. Matthew (Matthew Rhys) and Alastair (Jason Barry) have remained dope-smoking slackers. Ambitious Charlotte lives with indolent Matthew.
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Thompson 2019 p. 105 He was constantly disappointed with enslaved workers who did not share his motivation and resisted his demands, leading him to regard them as indolent and insist that his overseers supervise them closely at all times.Morgan 2005 p. 410Twohig 2001 p.
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SMZL generally follows an indolent course with 10 year survival rates of 42-95%. About one- third of these deaths are unrelated to SMZL and ~5-10 of these deaths are due to the transformation of their SMZL disease to diffuse large C-cell lymphoma.
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It is mainly affects older adults and it affects both men and women almost equally. Indolent lymphoma is considered incurable most of the time, unless the disease is localised, but due to its slow growing nature and response to effective treatment, patients often have prolonged survival.
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The Globe and Mail, May 19, 1984. He published two further novels, Heartlands"Kreiner views Jamaica via indolent whites". Ottawa Citizen, January 12, 1985. and Contact Prints,Arnold E. Davidson, "Philip Kreiner's Contact Prints and the Problems of Colonial Representation" in Jean-Michel Lacroix, Image et récit.
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31; Wark, "Elizabethan Recusancy", p. 13. Such remarks reflect the tendency of modern historians to dismiss him as "weak", "indolent" or "negligent" and either "sound asleep" or "papist" in his role as bishop.A. L. Rowse, The England of Elizabeth, 2nd Edition, University of Wisconsin Press, 2003, p.
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Sackett found that adults in foraging and horticultural societies work, on average, about 6.5 hours a day, whereas people in agricultural and industrial societies work on average 8.8 hours a day.Sackett, R. 1996. "Time, energy, and the indolent savage. A quantitative cross-cultural test of the primitive affluence hypothesis".
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The painting depicts a demon sitting atop a mountain. His flexed musculature and wrought hands contrast vividly with his slumped figure and sad facial expression. He appears at once passive, introverted, proud and solitary. His body shows contrasting masculinity and femininity with his long hair and indolent gaze.
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Patients with indolent lymphoma normally present with painless, swollen lymph nodes, often in the neck, armpit or groin. Sometimes patients have swollen lymph nodes inside their body, such as the chest or abdomen, which can stay undetected until they become very large and cause symptoms like cough and abdominal pain.
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For Le Petit Journal, the song is "a solid, tenderly naughty and very catchy composition". Backchichinfo stated: ""Appelle mon numéro" holds the attention, with an effective verse and a certain general freshness." According to Royer, the song demonstrates a sense of "indolent humor" and is "musically successful".Royer, 2008, p. 279.
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Returning east, on 6 November 1878 he met an encampment of friendly Tehuelche people in the Shehueu valley. He found that they were tall, as had been reported earlier, indolent and addicted to gambling, but kind and hospitable. They lived by hunting. Lista made a collection of words in their language.
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Pedreira & Costa, o. 8. The king is popularly shown as indolent, silly and clumsy, subjugated by a shrewish wife, a disgusting glutton who always had baked chicken in his coat pockets to eat them at any time with greasy hands,Loyola, Leandro. "Não havia Brasil antes de Dom João". Entrevista com Lúcia Bastos.
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A very interesting case is the myelodysplastic syndrome: Some rapidly change to acute leukemia, whereas others remain indolent for very long time. Identification of those tending to change to overt leukemia is important for the treatment. A relationship between the prognosis and the serum TK1 values has been demonstrated in myelodysplastic syndrome .
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With single or prolonged exposure by inhalation the lungs may become sensitized to beryllium. Berylliosis has an insidious onset and runs an indolent course. Some people who are sensitized to beryllium may not have symptoms.OSHA Beryllium Health Effects Page accessed March 29, 2016 Continued exposure causes the development of small inflammatory nodules, called granulomas.
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For low-grade astrocytomas, removal of the tumor generally allows functional survival for many years. In some reports, the 5-year survival has been over 90% with well- resected tumors. Indeed, broad intervention of low-grade conditions is a contested matter. In particular, pilocytic astrocytomas are commonly indolent bodies that may permit normal neurologic function.
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In humans, Erysipelothrix rhusiopathiae infections most commonly present in a mild cutaneous form known as erysipeloid or fish poisoning. E. rhusiopathiae can cause an indolent cellulitis, more commonly in individuals who handle fish and raw meat. Erysipelothrix rhusiopat also causes Swine Erysipelas. It is common in domestic pigs and can be transmitted to humans who work with swine.
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Refractory corneal ulcers are superficial ulcers that heal poorly and tend to recur. They are also known as indolent ulcers or Boxer ulcers. They are believed to be caused by a defect in the basement membrane and a lack of hemidesmosomal attachments. They are recognized by undermined epithelium that surrounds the ulcer and easily peels back.
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He decided to present the young composer a copy of the score of his Manfred Symphony, and once he had actually met the person whom Tchaikovsky authority David Brown called "indolent, fastidious, very private yet very engaging", his attitude toward Lyadov took a sharp turn for the better. The younger composer became known as "dear Lyadov".
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Waldenström's macroglobulinemia (; WM) is a type of cancer affecting two types of B cells: lymphoplasmacytoid cells and plasma cells. Both cell types are white blood cells. WM is characterized by having high levels of a circulating antibody, immunoglobulin M (IgM), which is made and secreted by the cells involved in the disease. WM is an "indolent lymphoma" (i.e.
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WM is a rare disease, with only about 1,500 cases per year in the United States. WM occurs more frequently in older adults. While the disease is incurable, it is treatable. Because of its indolent nature, many patients are able to lead active lives, and when treatment is required, may experience years of symptom-free remission.
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Refractory corneal ulcer Refractory corneal ulcers are superficial ulcers that heal poorly and tend to recur. They are also known as indolent ulcers or Boxer ulcers. They are believed to be caused by a defect in the basement membrane and a lack of hemidesmosomal attachments. They are recognized by undermined epithelium that surrounds the ulcer and easily peels back.
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The lower the percentage, the lower the speed of maturity, and the more indolent the disease. Katzenberger et al. Blood 2006;107:3407 graphs survival versus time for subsets of patients with varying Ki-67 indices. He shows median survival times of about one year for 61-90% Ki-67 and nearly 4 years for 5-20% Ki-67 index.
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That is, some cases of variant NLPHL, which is a relatively indolent malignancy, share with THRLBCL similar disease presentations, histologies (i.e. microscopic appearances), genetic abnormalities, and apparent etiologies. Indeed, NLPHL can, in rare cases, progress into THRLBCL. Comapared to THRLBCK, however, these variant NLPHL cases are less aggressive, are more responsive to treatment, and have a better prognosis.
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These were played about 1715. Evans had a good voice and just delivery, and was an actor in request. He was, however, corpulent and indolent. Playing at Cork ‘in the last year of the reign of Queen Anne,’ he was invited by some officers then on duty to a tavern, where he proposed the health of the queen.
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EHE typically occurs in the 20 – 40 age range although the overall age range involved is much broader and a modest predilection for females over males. It often has an indolent course, and many affected people have survived for decades with multi-organ disease.[1]:601 The extent and number of organs involved apparently has little effect on longevity.
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Small thyroid cancers (less than 2 cm) tend to have an indolent course, with favourable prognosis even if not treated. Less than 7 % of the imaging-detected ITNs are seen in younger populations. However, Shetty et al. found a higher rate of malignancy in the ITNs detected on CT scans among patients younger than 35 years.
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Bronson's writings throw light on the Noctes of the day. In his accounts he referred to dress, jewelry, customs, and language usage as well as the economy and political system of the tribe. Men (particularly the warriors) had their heads and ears ornamented with shells and precious stones. Describing their wild habits, he mentioned that they were indolent and had an untamed nature.
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He began to plot against the Praetorian Prefect Tigidius Perennis, who exercised the chief responsibilities of government since the indolent Commodus preferred not to concern himself with administration.Cassius Dio, Roman History LXXIII.9 In 184 he enabled a detachment of soldiers from Britain brought to Italy to suppress banditry, to denounce Perennis to the Emperor. Commodus gave them permission to execute the Prefect.
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A pas de bourrée piqué picks up the feet in between steps."Ballet Dictionary", ABT website. In his Der Vollkommene Capellmeister (Hamburg, 1739), Johann Mattheson wrote of the bourrée, "its distinguishing feature resides in contentment and a pleasant demeanor, at the same time it is somewhat carefree and relaxed, a little indolent and easygoing, though not disagreeable".Bach. The French Suites: Embellished version.
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Lando also allied with Guy III of Spoleto against Atenulf, his own brother, the gastald of the Marsi. Erchempert here gives an indication of Lando's character, describing him as too indolent to even take action against his brother, who was then befriending his worst enemy. Lando died in 885 of natural causes. He had married a daughter of Radelgar of Benevento.
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Mezerein can be found in Daphne mezereum. This plant has been used to make dyes, treat rheumatism and indolent ulcers and as a cosmetic. In homeopathy, the plant is used to treat primarily skin disorders but is also prescribed to treat anxiety related to digestive disorders and congestion. Once the toxicity of the plant was discovered, these uses were abandoned.
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They can show the cortical destruction of advanced osteomyelitis, but can miss nascent or indolent diagnoses. Confirmation is most often by MRI. The presence of edema, diagnosed as increased signal on T2 sequences, is sensitive, but not specific, as edema can occur in reaction to adjacent cellulitis. Confirmation of bony marrow and cortical destruction by viewing the T1 sequences significantly increases specificity.
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During his grandfather's reign, Mu'azzam was appointed vizer of Lahore from 1653-1659. Muazzam was replaced by Shaista Khan as the governor of Deccan. Shivaji raided the outskirts of Mughal Deccan's capital Aurangabad while the indolent Mu'azzam did little to prevent it. Enraged at this, Aurangzeb sent his most able commander Raja Jai Singh to capture Shivaji and he was successful.
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New immigration, of both Mexican and foreigners, increased pressure on the Alta California government to seize the Church-controlled mission properties and dispossess the natives in accordance with Echeandía's directive.Kelsey, p. 21: Settlers made numerous false claims in order to diminish the natives' abilities: "The Indians are by nature slovenly and indolent", stated one newcomer. "They have unfeelingly appropriated the region", claimed another.
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Sparsit – is a widow who has fallen on hard times. She is employed by Bounderby, and is jealous when he marries Louisa, delighting in the belief that Louisa is later about to elope with James Harthouse. Her machinations are unsuccessful and she is ultimately sacked by Bounderby. James Harthouse – is an indolent, languid, upper-class gentleman, who attempts to woo Louisa. Mrs.
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Saksenaea vasiformis usually causes cutaneous or subcutaneous zygomycosis, but can also cause primary sinusitis and rhinocerebral disease. Cutaneous diseases by S. vasiformis present red blisters. with necrotic ulcers or raised red to purple lesions. Infections by S. vasiformis are normally localized and indolent, but in some cases infection is disseminated or becomes highly invasive, and these cases were all fatal.
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The findings on chest imaging in DIPNECH patients are bilateral and diffuse. The most frequent findings on a computed tomography (CT) of the chest are multiple primary nodules and/or masses, on a background of mosaic attenuation and airway wall thickening. The nodules have an indolent pattern of growth and are found throughout the lungs. The nodules are typically rounded and well-defined.
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This disease is known for an indolent clinical course and incidental discovery. The most common physical finding is moderate splenomegaly. B symptoms are seen in a third of cases, and recurrent infections due to anaemia and/or neutropenia are seen in almost half of cases. Rheumatoid arthritis is commonly observed in people with T-LGLL, leading to a clinical presentation similar to Felty's syndrome.
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This may have contributed to increased tensions with ethnic and religious groups in the West.MMU Psychology Journal (Dissertations) In literary studies, critics such as Homi Bhabha and Rey Chow have theorized that cultural stereotypes prevail because they work through repetition and ambivalence, easily shifting between contradictory meanings. Thus in colonial culture the 'native' or 'ethnic' is stereotyped as sly and indolent, lascivious and impotent.Bhabha, Homi.
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467 The passive citizens still strived for acceptance and the supply of weapons. Danton proposed that the Assembly should authorize house searches ‘to distribute to the defenders of the "Patrie" the weapons that indolent or ill-disposed citizens may be hiding’. The section Sans-culottes organized it self as surveillance committee, conducting searches and making arrests all over Paris.R. Dupuy (2010) La Garde nationale 1789-1872.
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In particular for pilocytic astrocytomas (commonly indolent bodies that may permit normal neurologic function), surgeons may decide to monitor the neoplasm's evolution and postpone surgical intervention for some time. However, left unattended these tumors may eventually undergo neoplastic transformation. If surgery is not possible, recommendations such as chemotherapy or radiation may be suggested. However, side effects from these treatments can be extensive and long term.
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The film revolves around a woman who has been mistreated by her step-mother and forced into a marriage she disapproves. Saleem played the role of Vileena, an indolent daughter who ill-treats her own mother. It was followed by year's most successful Maldivian film, Ahmed Nimal's horror classic Zalzalaa (2000) where Saleem played the role of Nashfa, an irresponsible wife who abandons her only child.
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The name is derived from the Occitan words fleunheFrederic Mistral, Lou Tresor dóu Felibrige: FLEUNHE: (rom. fenis, débile) Mou, faible, défaillant, douillet and flaunhard,Frederic Mistral, Lou Tresor dóu Felibrige: FLAUNHARD: (rom. flaugnard) Mignard avec niaiserie, qui se plaint pour peu de chose, douillet, faible, indolent which both translate as "soft" or "downy". The dish is common in the Auvergne, Limousin and Périgord regions of France.
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There are several possible theories as to why Mubarak may have assassinated his half-brothers. One theory is that Mubarak resented being constantly sent away on tribal expeditions out into the desert. A second related theory is that Muhammad did not adequately fund Mubarak's expeditions. The third theory is that Muhammad was a weak and “indolent” leader whose unpopularity in Kuwait necessitated his removal.
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Who might this late comer be? Nobody was interested to > inquire. Still, indolent eyes were turned toward the distant entrance, and > we saw the silken gleam and the lifted sword of a guard of honor plowing > through the remote crowds. Then we saw that end of the house rising to its > feet; saw it rise abreast the advancing guard all along like a wave.
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He defends the Filipinos by saying that they are by nature not indolent, because in fact, even before the arrival of Spaniards, Filipinos have been engaged in economic activities such as agriculture and trade. Indolence therefore has more deeply rooted causes such as abuse and discrimination. A similar work was written by Syed Hussein Alatas, entitled The Myth of the Lazy Native.Syed Hussein Alatas (2010).
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The disorder is usually indolent or slowly progressive but may proceed to a leukemic phase sometimes classified as acute eosinophilic leukemia. Lymphocyte-variant hypereosinophilia can therefore be regarded as a precancerous disorder. The disorder merits therapeutic intervention to avoid or reduce eosinophil-induced tissue injury and treat its leukemic phase. The latter phase is aggressive and typically responds relatively poorly to anti- leukemia chemotherapeutic drug regimens.
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In the village, a neighbour has reappeared: William Bule, son of a leading local family. He has recently returned from America, a bad marriage and two children, whose ages he cannot bother to remember. Bill is indolent and insinuating and at the village cricket match he catches Anne's eye. Because of him, she suggests to her reluctant husband that they should have neighbours over for drinks.
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A pivotal study published in 1993 compared CHOP to several other chemotherapy regimens (e.g. m-BACOD, ProMACE-CytaBOM, MACOP-B) for advanced non-Hodgkin's lymphoma. CHOP emerged as the regimen with the least toxicity but similar efficacy. However, in Germany in 2012, bendamustine has displaced [R-]CHOP to become the first line treatment of choice for indolent lymphoma (a less aggressive subset of non-Hodgkin lymphoma).
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"Soul Sound" was recorded at the Matrix Recording Studios in London, England. "Soul Sound" is a pop record that experiments with pop-rock balladry. The song features guitar and bass instrumentation, and according to the Daily Mail, evokes the music of harmony groups from the 1960s. John Mulvey of NME characteristed the song as having "tasteful slippery beats, tasteful acoustic guitars, [and] the usual indolent harmonies".
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"Slack Motherfucker" is a song by American rock band Superchunk. It was the first single released from the band's debut, self-titled album (1990). The song was penned by vocalist and guitarist Mac McCaughan in reference to an indolent co-worker he had at the time. Credited to all four band members, it was the band's second single and first to be released under the name Superchunk.
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The elder, Sayed Kasim, is an officer in the Indian Army. The younger, Ahmed Kasim, is an indolent playboy, who, in MAK's view, wastes his time in a sinecure as secretary to the Nawab. Several historical persons, such as Abul Kalam Azad, a prominent Muslim politician who stayed with the Congress and opposed partition, may serve as the basis for the character of Kasim.
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Governor Arthur. This was designed to show that colonists and aboriginals were equal before the law, and incorrectly depicted a policy of friendship and equal justice which simply did not exist at the height of the Black War. Davey appears to have had no qualifications for his position. He was indolent and without sense of dignity, and indulged fully in the hard-drinking that was a characteristic of the period.
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The oil is fungistatic and fungicidal to Microsporum nanum at concentrations of 2.0 and 2.5 µL/mL respectively. The treatment completely inhibits the mycelia growth of the ringworm caused by Microsporum nanum, Epidermophyton floccosum, Trichophyton rubrum, and Trichophyton violaceum. No adverse effect is reported yet. In addition, the juice from the rhizome of Curcuma longa also be used to treat skin infections, indolent ulcers, inflamed joints, and in purulent ophthalmia.
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Wubble-U was an English dance music act of the mid-1990s, that was signed to BMG's independent record label, Indolent Records. Members were Laurant Webb, Justin Bailey, Dave Pine, Charlotte Fairman and Dave Coker, and became most famous for the single, "Petal". This was originally a 1994 release, that featured the comedian Stanley Unwin. A 1998 re-release took the track to number 55 in the UK Singles Chart.
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Noting the soil to be fertile, Babcock believed the Dominican Republic could feed 4 million people. Babcock, however, said the people of the Dominican Republic were "indolent and ignorant." Babcock's view, however, of the mixed race black people, did not impede his vision of Santo Domingo's inclusion by the United States. Babcock was a Reconstruction man, who was "nicely color-blind" to opportunism, in the post Civil War world.
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However, FDSC, particularly in cases with only lymph node involvement, usually has an indolent course with a low rate (~10%) of metastasis. In these cases, surgical removal appears to be the treatment of choice; the role of radiation and chemotherapy here is not well-defined. Cases with extranodal involvement, especially those with abdominal tumors, have a higher metastatic rate (~20%). Chemotherapy regimens remain the mainstay for treating disseminated FDCS.
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Maria Bertram is the eldest daughter and third child in a wealthy family that owns the large country estate, Mansfield Park. Her father, Sir Thomas Bertram, is a baronet. She has two older brothers and one sister a year younger than herself. She grows up treated with stern distance by her father, kindly ignored by her indolent, self-centred mother, but spoiled and indulged by her Aunt Norris.
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Cyclin D1 negative mantle cell lymphoma can be diagnosed by detecting SOX11 marker. The workup for Mantle cell lymphoma is similar to the workup for many indolent lymphomas and certain aggressive lymphomas. Mantle cell lymphoma is a systemic disease with frequent involvement of the bone marrow and gastrointestinal tract (generally showing polyposis in the lining). There is also a not-uncommon leukemic phase, marked by presence in the blood.
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He becomes increasingly despondent and indolent, and turns to alcohol and women, while Oshin turns a blind eye because of her love for him. After a confrontation during which Ryuzo makes clear his bitterness, Oshin realises that her working to supporting the family had wounded his pride. She decides that it would be better for Ryuzo if she were to leave him. However, Oshin then discovers that she is pregnant.
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Recently, however, monoclonal B-cells with some key characteristics of the malignant B-cells in FL or MCL have been found to accumulate in one or more lymphoid tissues. These accumulations are localized, non-destructive (i.e. not effacing a tissue's normal architecture), premalignant, and therefore now regarded as in situ disorders similar to those in solid tissues. ISFN and ISMCL are usually indolent, asymptomatic disorders that rarely progress to malignancy.
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Kelsey, p. 21Settlers made numerous false claims to diminish the natives' abilities: "The Indians are by nature slovenly and indolent," stated one newcomer. "They have unfeelingly appropriated the region," claimed another. Despite the fact that Echeandía's emancipation plan was met with little encouragement from the novices who populated the southern missions, he was nonetheless determined to test the scheme on a large scale at Mission San Juan Capistrano.
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Extranodal marginal zone B-cell lymphomas (also termed MALT lymphomas) are generally indolent malignancies. Recommended treatment of H. pylori-positive extranodal marginal zone B-cell lymphoma of the stomach, when localized (i.e. Ann Arbor stage I and II), employs one of the antibiotic- proton pump inhibitor regiments listed in the H. pylori eradication protocols. If the initial regimen fails to eradicate the pathogen, patients are treated with an alternate protocol.
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The narrator in the book recounts a conversation with Jean-François Rameau, nephew of the famous Jean-Philippe Rameau. The nephew composes and teaches music with some success but feels disadvantaged by his name and is jealous of his uncle. Eventually he sinks into an indolent and debauched state. After his wife's death, he loses all self-esteem and his brusque manners result in him being ostracized by former friends.
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The main use of serum TK1 activity assays is in non-Hodgkin lymphoma. This disease has a wide range of aggressivity, from slow-growing indolent disease that hardly requires treatment to highly aggressive, rapidly growing forms that should be treated urgently. This is reflected in the values of serum TK1 activity, that range from close to the normal range for slow-growing tumors to very high levels for rapidly growing forms.
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Eikenella corrodens infections are typically indolent (the infection does not become clinically evident until a week or more after the injury). They also mimic anaerobic infection in being extremely foul-smelling. Eikenella corrodens was mentioned in an episode of Forensic Files, in which a hotel employee punched a woman in the mouth, knocking out two of her teeth. The tooth bacteria caused a major infection in the man's hand.
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DFL is generally an indolent disease which progresses to a more aggressive form in <10% of cases. A watch-and-wait strategy has been a generally recommended treatment for the disease in the United States, Japan, and Europe. However, numerous approaches have been used to treat the disease. Patients with disease that is contained within a limited radiation field have been treated with radiation therapy to attain overall 10 year survival rates of 60-80%.
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He was the Rector at Aberdeen University from 1794–6. In a confidential report titled "View of the political state of Scotland" published in 1788, Ferguson was described as "a man of real good sense, but indolent." The document was published in 1887 but covered the personal circumstances of those involved in county elections in Scotland during the previous century. Ferguson was not a good-looking man and appeared plain, small and stocky.
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NMZL is considered an incurable but relatively indolent disease that takes a slowly progressive, relapsing course. Its prognosis appears to be slightly worse than that seen in extranodal and splenic marginal zone lymphomas with ~15% of people progressing to a more aggressive lymphoma, diffuse large B cell lymphoma, at median time of ~4.5 years after the diagnosis of NMZL. In different studies, people with the disease have 5 year survival rates of 62-90%.
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The 1993 Stephen Duffy album Music in Colors (Parlophone) was recorded with Nigel Kennedy, and featured the singles "Natalie" and "Holte End Hotel". The next album was called simply Duffy, released in August 1995 on Indolent Records. "London Girls" and "Sugar High" went to the top 10 on the UK indie chart. ("Starfit" was also released as a single in the US.) The album was reissued on CD in 2000 by BMG Fun House.
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Charles the Child was crowned at Limoges and buried at Bourges. When Aquitaine briefly asserted its independence after the death of Charles the Fat, it was Ranulf II of Poitou who took the royal title. In the late tenth century, Louis the Indolent was crowned at Brioude. The Aquitainian ducal coronation procedure is preserved in a late twelfth- century ordo (formula) from Saint-Étienne in Limoges, based on an earlier Romano-German ordo.
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Although indolent lymphoma tends to progress slowly and the median overall survival is lengthy (more than 10 years), patients have a heterogenous prognosis both within and between different subtypes.Some patients live many years longer than the estimated median survival, some die in a short period after diagnosis. Patients with HIV infection tends to have similar median survival than patients who are HIV negative. Younger patients have higher fiver year survival than older patients.
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Of a visit to San Francisco Morrell writes: "The inhabitants are principally Mexicans and Spaniards who are very indolent and consequently very filthy." After revisiting the Galapagos Islands and gathering a harvest of fur seal and terrapin,Morrell uses the word "terrapin", presumably referring to the Galapagos tortoise. The terms were used interchangeably in Morrell's day; for example see Charles Darwin in , p. 312 Tartar began a slow journey home on October 13, 1825.
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Swift in an elevator with co-workers in the music video for "Ours". The video begins as Swift, dressed as an office worker, passes through the lobby to the elevator and greets the people she meets. As the elevator's door closes, Swift begins to sing, looking indolent and slothful, seeing the people surrounding her in the elevator. As the elevator reaches the thirteenth floor, people surrounding her start to exit, nudging her.
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Hooker regularly corresponded with the chief government scientist in New Zealand, Sir James Hector. He sent his son Willy (aged 15) to stay in New Zealand with the recently married Hector in 1869, Willy was sickly and coughing up blood, and a warmer climate was recommended. Though well-behaved he was indolent. Hector sent him on a cruise on a Government steamer the Sturt with a son (also 15) of Colonel Haultain the Defence minister.
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Prostate cancer is in most cases a slowly progressive disease. However, early localized disease is curable whereas metastatic disease is not. Thus, a continued debate among clinicians is whether to treat early to prevent disseminated disease, or observe and delay treatment until there is evidence of progression. The former risks harm from overtreatment of an indolent disease; whereas the latter risks missing an opportunity for cure among those destined to experience progression.
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Rituximab is a chimeric monoclonal IgG1 antibody specific for CD20, developed from its parent antibody Ibritumomab. As with ibritumomab, rituximab targets CD20, making it effective in treating certain B-cell malignancies. These include aggressive and indolent lymphomas such as diffuse large B-cell lymphoma and follicular lymphoma and leukemias such as B-cell chronic lymphocytic leukemia. Although the function of CD20 is relatively unknown, CD20 may be a calcium channel involved in B-cell activation.
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In situ vaccine (ISV), combining Flt3L, local radiotherapy, and a TLR3 agonist (poly-ICLC), could recruit, antigen- load and activate intratumoral cross-presenting dendritic cells (DCs) in indolent non-Hodgkin’s lymphomas (iNHLs) treatment (clinical trial: NCT01976585). In this study, intratumoral Flt3L was able to (1) induce the accumulation of large numbers of TLR3+ DCs in the tumor and (2) mediate , together with local irradiation, cross-presentation of TAA by DCs in vitro and in vivo.
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The Prince Regent was prevented from using the full powers of kingship. The regent became George IV in 1820, but during his 10-year reign was indolent and frivolous. Consequently, for 20 years the throne was virtually vacant and Tory Cabinets led by Tory prime ministers filled the void, governing virtually on their own. The Tories were in power for almost 50 years, except for a Whig ministry from 1806 to 1807.
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Scene from The Pagan Trader Henry Slater (Donald Crisp) stops at a South Pacific island looking to obtain a cargo of copra. He is informed that half-caste Henry Shoesmith, Jr. (Ramon Novarro) owns the largest plantation, but is rather indolent. Meanwhile, Shoesmith is lolling around, while admirer Madge (Renée Adorée), wishes she had met him before she became a fallen woman. Then the young man hears a woman singing aboard a ship.
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At international level, they have always supported oppressed people and opposed of child labour, and continued campaigning against the death sentence in India and worldwide in addition to speaking out against the violation of human rights. Currently, IWA (G.B) is campaigning for the inquiry of the indolent of British Govt who gave advice to the Indian Govt to launch the attack on Harmandir Sahib, Amritsar in 1984. The Indian Workers Association (G.
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The clinical presentation of CST can be varied. Both acute, fulminant disease and indolent, subacute presentations have been reported in the literature. The most common signs of CST are related to anatomical structures affected within the cavernous sinus, notably cranial nerves III-VI, as well as symptoms resulting from impaired venous drainage from the orbit and eye.Classic presentations are abrupt onset of unilateral periorbital edema, headache, photophobia, and bulging of the eye (proptosis).
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His Border Police troopers appear to have been equally neglectful of their duties, letting prisoners escape and leaving the squatters to undertake forceful measures against bushrangers. There is one instance, after Aboriginal people speared cattle on the Castlereagh River, Hunter sent down three troopers. Hunter found the Aboriginal Australians indolent and lazy. Hunter also stated that there was bloodshed when settlers took Aboriginal women to work in slavery on their pastoral properties.
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However, the disease differed from the aggressive lymphomas which it mimicked in having a prolonged and usually non-progressive course. Furthermore, the disorder's lesions consisted of normal-appearing T cells that proliferated very slowly and usually caused little or no tissue destruction. In 2017, the World Health Organization provisionally classified ITCLD-GT as an extranodal (i.e. usually not involving lymph nodes), indolent disorder in which various subtypes of T cells proliferate in the GI tract.
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Clinical symptoms include diarrhea, fever, fatigue, nausea, cough, pneumonia, abdominal pain, chills and rash. Laboratory abnormalities may include: neutropenia, hypertriglyceridemia, hyperglycemia and elevated levels of liver enzymes. Idelalisib's safety and effectiveness to treat relapsed FL and relapsed SLL were established in a clinical trial with 123 participants with slow-growing (indolent) non-Hodgkin lymphomas. All participants were treated with idelalisib and were evaluated for complete or partial disappearance of their cancer after treatment (objective response rate, or ORR).
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MOE follows a much more chronic and indolent course than ordinary acute otitis externa. There may be granulation involving the floor of the external ear canal, most often at the bony-cartilaginous junction. Paradoxically, the physical findings of MOE, at least in its early stages, are often much less dramatic than those of ordinary acute otitis externa. In later stages, there can be soft tissue swelling around the ear, even in the absence of significant canal swelling.
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These include cutaneous T-cell lymphoma (mycosis fungoides and sézary syndrome), follicular lymphoma (FL), marginal zone lymphoma, small cell lymphocytic lymphoma (SLL)/chronic lymphocytic leukemia (CLL) and lymphoplasmacytic lymphoma/Waldenström macroglobulinemia. Follicular Lymphoma (FL) is the most common subtype. Indolent lymphoma accounts for 41 percent of all NHL cases in North America and North Europe, white people have higher incidence rates than black and Asian people.The cause of the racial, ethnic and geographical disparities is poorly understood.
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First degree family history of NHL, hematological malignancy and hepatitis C virus (HCV) infection are linked to an increased risk of indolent lymphoma (iNHL).There are also specific risk factors related to iNHL sub-types. Higher body mass index (BMI) as a young adult, occupation as a spray painter, sedentary lifestyle, high level of dietary animal protein intake are associated with risk of follicular lymphoma.Residence on farm are associated with an increased risk of mantle cell lymphoma.
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Marginal zone lymphoma (MZL) is a heterogeneous group of indolent B cell NHL that arises from the marginal zone of lymphoid tissues. It accounts for 5~10% of all NHL cases, with an annual incidence of 0.4 to 1.0 per 100,000 cases in Western countries. The median age of diagnosis is 67 years, and it is slightly more common in women than in men.The World Health Orgnisation categorises MZL into three distinct subtypes: nodal, extranodal and splenic.
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A year later while Ibrahim, progressively crippled by rheumatic pains and tuberculosis (he was beginning to cough up blood), was sent to Italy to take the waters, Muhammad Ali, in 1846, travelled to Constantinople. There he approached the Sultan, expressed his fears, and made his peace, explaining: "[My son] Ibrahim is old and sick, [my grandson] Abbas is indolent (happa), and then children will rule Egypt. How will they keep Egypt?"Nubar Pasha,Memoirs, p.63.
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Most cases are asymptomatic or are discovered during an investigation of blood in the urine. Symptomatic patients typically present as middle-aged adults with renal colic, kidney stones, nephrocalcinosis and/or recurrent urinary tract infections; however, MSK also may affect children very rarely. In addition to the typical clinical phenotype of recurrent stone disease, other clinical profiles have now been recognized, that is, an indolent, almost asymptomatic MSK, and a rare form characterized by intractable pain.
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If untreated, many cases progress over a period of months to years to become disseminated blastomycosis. In these cases, the large Blastomyces yeast cells translocate from the lungs and are trapped in capillary beds elsewhere in the body, where they cause lesions. The skin is the most common organ affected, being the site of lesions in approximately 60% of cases. The signature image of blastomycosis in textbooks is the indolent, verrucous or ulcerated dermal lesion seen in disseminated disease.
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The paintings showed an amalgamation of his traditional training, through the technicality, with the more experimental style of the Europeans at the time, seen in the sensibility. Meeting his wife, Jeanne Heloise Morel, in 1895, his style shifted to a Pre-Raphaelite depiction of romantic, indolent female figures. Morel was continually depicted in these paintings, and has been referred to as Bunny's "eternal muse", such as in the works Returning from the garden (1906) and Jeanne (1902).
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Despite the grandeur of their surroundings and the refinement of their furnishings, planters such as the Fairfaxes, Masons, McCartys, and Washingtons did not lead indolent lives. Conscious of their civic duty and of the elite class, they were the political, social, economic, and religious leaders of their immediate neighborhood and of the colony at large. In 1741, Fairfax was elected a member of the House of Burgesses.Lindsay Fairfax, An Historic Sketch of The Two Fairfax Families, p.
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Three generations of the Leonides family live together under wealthy patriarch Aristide. His first wife Marcia died; her sister Edith has cared for the household since then. His second wife is the indolent Brenda, decades his junior, suspected of having a clandestine love affair with Laurence, the grandchildren's tutor. After Aristide is poisoned by his own eye medicine (eserine), his granddaughter Sophia tells narrator and fiancé Charles Hayward that they cannot marry until the killer is apprehended.
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The film was critically appreciated by critics and was a Hit commercially by screening twenty six housefull shows at cinema. Amjad Ibrahim-directed Ainbehge Loabi Firiehge Vaajib, starring Saeed, Yoosuf Shafeeu, Jamsheedha Ahmed, Arifa Ibrahim and Niuma Mohamed was released in 2000. The film revolves around a woman who has been mistreated by her step- mother and forced into a marriage she disapproves. Saeed played the fiancé of Vileena who is an indolent daughter ill-treating her own mother.
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It is indicated as a single-agent or in combination with other anti- cancer agents for indolent non-Hodgkin's lymphoma, multiple myeloma, and chronic lymphocytic leukemia. SymBio Pharmaceuticals Ltd. holds exclusive rights to develop and market bendamustine HCl in Japan and selected Asia Pacific Rim countries. In March 2008, Cephalon received approval from the United States Food and Drug Administration to market bendamustine in the US, where it is sold under the tradename Treanda, for treatment of chronic lymphocytic leukemia.
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As a result, landholders were unsupervised or they reported to corrupt and indolent officials. The result was that revenues were extracted without regard for future income or local welfare. Following the devastating famine of 1770, which was partially caused by this short-sightedness, Company officials in Calcutta better understood the importance of oversight of revenue officials. They failed to consider the question of incentivisation; hence Warren Hastings, then governor-general, introduced a system of five-yearly inspections and temporary tax farmers.
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Leonilla is wearing a luxurious gown of ivory silk moiré, with a pink sash around her waist. A deep purple mantle wraps around her back and falls across her arms. She gazes languidly at the viewer while she toys with the large pearls around her neck in an indolent gesture, reinforcing the sensuality of the model. Winterhalter contrasted the sumptuous fabrics and vivid colors against the princess's alabaster flesh to heighten the sensuality of the pose, the model, and the luxuriant setting.
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The course of pediatric NMZL is extremely indolent with the disease having a low relapse rate and typically an excellent outcome. Observation perionds of up to 12–18 years have found that patients have overall survival rates of 100% and relapse rates of ~4%. Treatment of pediatric NMZL has used a watchful waiting strategy, rituximab, chemotherapy, and/or local radiation therapy. The watchful waiting strategy has done as well as the other therapies and is therefore the recommended initial treatment for the disease.
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Strongyloidiasis in immunocompetent individuals is usually an indolent disease. However, in immunocompromised individuals, it can cause a hyperinfective syndrome (also called disseminated strongyloidiasis) due to the reproductive capacity of the parasite inside the host. This hyperinfective syndrome can have a mortality rate close to 90% if disseminated. Immunosuppressive drugs, especially corticosteroids and agents used for tissue transplantation, can increase the rate of autoinfection to the point where an overwhelming number of larvae migrate through the lungs, which in many cases can prove fatal.
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In By Sheer Pluck: A Tale of the Ashanti War, Mr. Goodenough, an entomologist remarks to the hero: > They [Negroes] are just like children ... They are always either laughing or > quarrelling. They are good-natured and passionate, indolent, but will work > hard for a time; clever up to a certain point, densely stupid beyond. The > intelligence of an average negro is about equal to that of a European child > of ten years old. ... They are fluent talkers, but their ideas are borrowed.
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Henry XI was very indolent and sickly person since his childhood. He settled his main residence in Kożuchów, which was the capital of his Duchy. After assumed the government, he didn't show greater political ambitions, because he lived all his adult life under the shadow of his father. Following the advises of the City Council of Wrocław he send a message to Kraków, where he encouraged King Casimir IV or one of his sons to take the throne of Bohemia.
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Carlota Joaquina's husband was good-natured, indolent, corpulent and almost as ugly as she was. His religious observances bored her, and they were quite incompatible. Nevertheless, she gave birth to nine children during their marriage and, because they were all handsome, it was rumoured that especially the younger ones had a different father. After Queen Maria I became insane in 1792, Prince John took over the government in her name, even though he only took the title of Prince Regent in 1799.
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Small renal tumors (< 4 cm) are treated increasingly by partial nephrectomy when possible. Most of these small renal masses manifest indolent biological behavior with excellent prognosis. Nephron-sparing partial nephrectomy is used when the tumor is small (less than 4 cm in diameter) or when the patient has other medical concerns such as diabetes or hypertension. The partial nephrectomy involves the removal of the affected tissue only, sparing the rest of the kidney, Gerota's fascia and the regional lymph nodes.
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As with several other Spark novels, one theme is the disintegration of 'timeless' values in modern society, in this instance the role of religion (represented by Hubert's bogus Diana cult and two indolent, chortling Catholic priests) and the role of money: mostly unseen, or buried. A larger-scale backdrop is provided by the 1973 oil crisis. Hubert's secretary, Pauline Thin, shares her surname with the Edinburgh-based stationer James Thin, who supplied Spark's notebooks in which she wrote all her novels in longhand.
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In 331 BC, he led an invasion of Scythian lands, "thinking that, if he did not attempt something, he should be stigmatized as indolent". For this purpose, he collected a force of thirty thousand men. They marched along the Black Sea coast and besieged Olbia, a colony of Miletus (which was taken by Alexander in 334 BC). But the Olbians "gave freedom to their slaves, granted the rights of citizenship to foreigners, changed promissory notes and thus managed to survive the siege".
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She has an innate curiosity for an interesting and genuine life. The themes of her purity and innocence equate closely with a being absolutely untainted by prejudices or judgment. At home, the stifling environment created by her Aunt Cissie and the indolent, annoying Mater drive Yvette to search for uncharted social waters. She is not ashamed of her response to nature when she confesses her strong attraction to the gipsy during conversations with her sister Lucille as well as Mrs.
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The few patients who have been treated with these alternate drugs have exhibited good responses in the majority of instances. Reslizumab, a newly developed antibody directed against interleukin 5 that has been successfully used to treat 4 patients with the hypereosinophilic syndrome, may also be of use for lymphocyte-variant eosinophilia. Patients suffering minimal or no disease complications have gone untreated. In 10% to 25% of patients, mostly 3 to 10 years after initical diagnosis, the indolent course of lymphocyte-variant hypereosinophilia changes.
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Aside from collecting taxes more efficiently, the French did little to transform Cambodia's village-based economy. Cambodians paid the highest taxes per capita in Indochina, and in 1916 a nonviolent tax revolt brought tens of thousands of peasants into Phnom Penh to petition the king for a reduction. The incident shocked the French, who had lulled themselves into believing that the Cambodians were too indolent and individualistic to organize a mass protest. Taxes continued to be sorely resented by the Cambodians.
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Ornea, p.100-101 This involved the denunciation of "foreign elements" and "minority islands", with a specific focus on the Jewish-Romanian community ("Jews make use of an indolent hospitality in order to deprive our kin of its ancient patrimony")Crainic, in Ornea, p.100-101 and its alleged connections with the political establishment ("In statements, in speeches and in acts of government our democrats have always declared themselves on the side of intruders and the allogeneous").Crainic, in Ornea, p.
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PFTL is an extremely indolent disease which is manifested by lesions that exhibit a typical FL histology or, more commonly, a mixed FL-diffuse large cell lymphoma histology. It usually involves a 2-4 centimeter lesion in a single testicle. Patients have been treated with removal of the involved testes followed by various standard anti- lymphoma chemotherapy regimens to attain excellent results, i.e. 100% completed remissions with no recurrence of disease in 15 child and adolescent patients observed for 4–96 months.
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At home, without fighting to distract him, Cornelis, or Kees as he was normally called, grew quickly bored and indolent. He had the reputation of being a heavy drinker, so much so that many inns at the time were named after him. Tromp was a vain man, having an extremely high opinion of himself, which he never hesitated in sharing with others. He felt that, son of a famous father, he had a natural right to the position of naval hero.
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Troyat described Anna as an "indolent day-dreamer" who spent her mornings reading novels in bed, only got up in the afternoon, liked to wander around her apartment barely dressed with her hair undone, and was principally interested in reading novels. Anna's preference for handing out government jobs to Baltic German aristocrats caused much resentment on the part of the ethnic Russian nobility who not for the first nor last time complained that a disproportionate number of Baltic Germans were holding high office.
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Pete (George Peppard) is a former advertising executive living a Beatnik–Bohemian life, as part of a commune in a New York City loft. Since living in the commune, Pete has turned into a cynical, misanthropic artist. The members of the commune are seemingly aimless, indolent or melancholy while waiting for the world to end; one member (Gillian Spencer) lives her life in a burlap sack, with only her bare feet protruding. One day, a wayward toucan arrives at the loft.
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He voted with the government, but was sent on another mission as minister to the Netherlands from 1733 to 1734. He had been admonished by Carteret previously for lack of diligence, and it was considered that his indolent ministry had put the Netherlands into the hands of France. Walpole sent his brother Horace to The Hague as ambassador on a special mission, and Finch took umbrage and asked to be recalled. He was returned unopposed at the 1734 British general election and went into opposition against Walpole.
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Pol Raos still levied from Idar. Syed Hatho was replaced by Kamal Khan, an indolent man whom Rao Gopinath drove out, and, regaining Idar, held it for five years (1664). Garibdas Rehvar, who was at the head of a party in Idar, fearing that Gopinath would take vengeance for Arjundas, brought an army from Ahmedabad to drive him out. The Rao fled to the hills and died for want of opium of which he was accustomed to take a pound and a quarter a day.
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Splenic marginal zone lymphoma (SMZL) is a low grade lymphoma in which malignant B-cells accumulate in the spleen, bone marrow, and, less commonly, the circulation. While generally an indolent disease, about 5-10% of cases transform into a far more aggressive malignancy, diffuse large B-cell lymphoma. In a variable percentage of cases, SMZL has been observed to occur with an increased incidence in individuals who are chronically infected with Hepatitis C virus or have any one of various chronic autoimmune diseases or abnormalities.
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Nadheem (Ahmed Asim), the only child of Naseer (Ali Shameel) and Wadheefa (Mariyam Shakeela), is secretly in love with his best-friend, Mariyam Shaanee (Niuma Mohamed), the indolent daughter of Seema (Aminath Rasheedha). While Nadheem's true feelings are concealed to Shaanee, she starts a romantic relationship with Shah (Lufshan Shakeeb), a cousin of Nadheem. However, things take an unfortunate turn when Seema reveals that Shaanee's father, on his dying bed, requested that Shaanee marries no one but Nadheem, which complicates her relationship with Shah.
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Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents such as chlorambucil alone. Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and rituximab in the treatment of indolent non-Hodgkin's lymphomas. As part of the FLAG or FLAMSA regimen, fludarabine is used together with cytarabine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to allogeneic stem cell transplant.
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Ahmed Zameel (Ibrahim Visan) working at an office in Male' visits an island to handover his friend, Moosa's assets and cashes to his family after his shocking death. There he meets a happy-go-girl Shiuna Ibrahim (Niuma Mohamed) and a relationship grows between them. Zameel reveals that he has previously married to an indolent and irresponsible lady, Nashfa (Neena Saleem) and they are blessed with a son before he divorces her. Shiuna promises to love his son as her own and they marry.
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Salles has been especially interested in the clinical and biological study of malignant lymphoma – major focuses of his work include the description and validation of prognostic factors as well as clinical trials in indolent lymphomas. He has been involved as a coordinator or co-investigator in many clinical trials and studies within his field. Gilles Salles has led a phase I/II study of rituximab, the antibody that is used most often in the treatment of lymphoma. Salles is the author of 303 publications.
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More than 2 dozen other genes have been reported to be mutated in rare cases of PTFL but in general the genetic abnormalities found in this disorder are fewer and less complex than those in other types of FL. PTFL has an indolent, relapsing and remitting course with a 5 year survival rate of >95%. Patients diagnosed with PTFL have been treated with chemotherapy, surgery, and combinations of these treatments. In general, these patients did well (100% survival with <5% of cases relapsing regardless of treatment modality).
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Anakinra (IL-1Ra) is FDA-approved as a therapy for patients with rheumatoid arthritis, because it reduces symptoms and slows joint destruction of this inflammatory disease. It has also been prescribed to patients with indolent or smoldering myeloma with a high risk of progression to multiple myeloma. In combination with other medication, IL-1Ra provides a significant increase in the number of years of progression-free disease in its recipients. The benefits of this treatment are the natural structure and no toxicity or gastrointestinal disturbances.
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Until the Republican reforms of 1995 banished the practice, proxy voting was also used in U.S. House of Representatives committees. Often members would delegate their vote to the ranking member of their party in the committee. Republicans opposed proxy voting on the grounds that it allowed an indolent Democratic majority to move legislation through committee with antimajoritarian procedures. According to this criticism, on days when Democratic committee members were absent, the Democratic leader in the committee would successfully oppose the sitting Republican majority by wielding the proxies of absent Democrats.
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Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is an indolent CD20(+) form of lymphoma. Some medical organizations no longer classify it as a form of classic Hodgkin lymphoma (HL). This is because the Reed-Sternberg cell (RSC) variants (popcorn cells) that characterize this form of the disease invariably express B lymphocyte markers such as CD20 (thus making NLPHL an unusual form of Hodgkin lymphoma), and that (unlike classic HL) NLPHL may progress to diffuse large B cell lymphoma. There are small but clear differences in prognosis between the various forms.
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Later, the name would be used by the dominant Singh Sabha faction in Lahore founded in 1879 to rival the Amritsar Singh Sabha. The name was used to connote Sikhs with full readiness and commitment to action on behalf of the Sikh community, in contrast to ḍhillaṛ, or "indolent, passive, ineffectual" Sikhs. The leader of the Tat Khalsa Singh Sabha was Bhai Gurmukh Singh, a professor at the Oriental College of Lahore. He contacted Kahn Singh Nabha, a notable scholar, who wrote Mahan Kosh (encyclopedia of Sikhism) and Ham Hindu Nahin (We are not Hindus).
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Song's breakout role came in the fusion historical drama Sungkyunkwan Scandal where he played the role of an 18th-century Joseon-era rich, indolent playboy. Despite stable but unspectacular ratings, the drama became a cult hit and his on-screen "bromance" with a then-unknown Yoo Ah-in was popular with viewers. Song also joined the cast of variety program Running Man from 2010 to 2011. Song later released the book Beautiful Skin Project, a bestselling health and beauty guide for men (which was re-released in Japan in 2013).
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As chemotherapy affects cell division, tumors with high growth rates (such as acute myelogenous leukemia and the aggressive lymphomas, including Hodgkin's disease) are more sensitive to chemotherapy, as a larger proportion of the targeted cells are undergoing cell division at any time. Malignancies with slower growth rates, such as indolent lymphomas, tend to respond to chemotherapy much more modestly. Heterogeneic tumours may also display varying sensitivities to chemotherapy agents, depending on the subclonal populations within the tumor. Cells from the immune system also make crucial contributions to the antitumor effects of chemotherapy.
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" Lee wrote that "The notion that some San in the 1980s remain untouched by 'civilization' is a cruel joke. The San have been the subject of a century of rapid social change and especially in the last twenty years have been forced to endure all the 'benefits' of South Africa's apartheid policies in Namibia." Gugler wrote that the guerrillas in the film are depicted as "bad Africans [...] dangerous and destructive all right, but they are also indolent and inept. In the end, even Kate Thompson gets to disarm one of them.
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4, pp. 100–5. What passes in the world for "good- nature", Hazlitt argues, "is often no better than indolent selfishness". The Lord Chancellor, as an example of a good-natured man, "would not hurt a fly ... has a fine oiliness in his disposition .... does not enter into the quarrels or enmities of others; bears their calamities with patience ... [and] listens to the din and clang of war, the earthquake and the hurricane of the political and moral world with the temper and the spirit of a philosopher ...".Hazlitt 1930, vol. 11, pp .141–42.
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Drury was elected to the Roxburghe Club on its first anniversary in 1813. He was elected a Fellow of the Royal Society in February 1818. Drury was considered the favourite candidate to succeed George Butler as headmaster of Harrow in 1829; Charles Longley, an Oxford academic and a last-minute external candidate, was instead appointed. Thereafter Drury's effectiveness as a schoolmaster declined: he became "increasingly eccentric, bad-tempered, and indolent", losing classroom control, missing morning lessons, wearing flowery dressing-gowns, eating fruit during lessons, and borrowing cigars from schoolboys.
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Jenna Lê is an American poet and medical doctor. A Minnesota-born daughter of Vietnam War refugees, Lê grew up outside Minneapolis and earned her B.A. in Mathematics from Harvard University and her M.D. from Columbia University. She lives and works in New York City. She is the author of two full-length collections of poems, Six Rivers (NYQ Books, 2011), which was a Small Press Distribution Poetry Bestseller, and A History of the Cetacean American Diaspora (Indolent Books, 2018; first edition: Anchor & Plume Press, 2016), which won Second Place in the 2017 Elgin Awards.
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Less commonly the disease comes to light only after the cancerous cells overwhelm the bone marrow resulting in low red blood cells, neutrophils, or platelets. Or there is fever, night sweats, weight loss, and the person feels tired. CLL is, in virtually all cases, preceded by a particular subtype of monoclonal B-cell lymphocytosis (MBL). This subtype, termed chronic lymphocytic leukemia/small lymphocyte lymphoma MBL (CLL/SLL MBL) is an asymptomatic, indolent, and chronic disorder in which individuals exhibit an increase in the number of circulating B-cell lymphocytes.
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Newspaper columnist Greg Sheridan said that Victorian Premier John Brumby was in "indolent denialism" regarding these incidents by saying that "Assaults on Indian students are under-represented as a population share." According to Sheridan, the Victorian Police had initially denied gathering statistics on crime by ethnicity, then reversed that and said they did collate such statistics, but said that they were unreliable. Sheridan was concerned that there was also systematic under-reporting of all crime in Victoria as claimed in the Victorian Ombudsman report "Crime Statistics and Police Numbers".
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Kingston, . Contemporary critics of the novel agreed that the title character was neither good nor likeable: The Spectator called her 'narrow-brained, shallow- hearted, indolent, and ill-conditioned'; The Standard, 'not in any sense a nice girl'. They also agreed that the work's titular 'experiment' is Lucilla's marriage to da Costa. The Pall Mall Gazette said that '[t]he experiment poor Lucilla makes is marrying a creole'; the Spectator, that '[t]he great experiment of the book is Lucilla's marriage with an unmistakeable half-caste, Isidore Da Costa, which proves disastrous enough'.
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Currently, the main goal of treating optic gliomas is to preserve the patient’s visions for as long as possible. The tumor’s indolent & self- limiting growth indicates that it is not immediately problematic in most benign cases, with long-term studies showing that optic glioma patients may still have stable functional vision without intervention. As a result, the first & preferred course of action is usually observation of the patient’s optic glioma over time. Once the first signs of visual deterioration and/or tumor progression are observed, interventional treatment will then commence.
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He was uncertain of their ethnic identity, classifying them as Germanic based on their way of life, but not based on their language (in comparison to, for example, the Peucini): > Here Suebia ends. I do not know whether to class the tribes of the Peucini, > Venedi, and Fenni with the Germans or with the Sarmatians. The Peucini, > however, who are sometimes called Bastarnae, are like Germans in their > language, manner of life, and mode of settlement and habitation. Squalor is > universal among them and their nobles are indolent.
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The Telegraph called hers "a name to watch" and The Independent compared her to Joan Fontaine in Rebecca. The Spectator said: "Brealey uncovers the pathetic poetry beneath the indolent superficialities. Her big disadvantage is that she’s too attractive for ‘plain’ Sonya, but she disguises this by suggesting a lack of sexual allure with awkward giggles, squirrelly movements and a stupefied beaming naivety. All brilliantly done..." In 2011 Brealey was the sex-mad, short- frocked daughter of Julian Barratt and Doon Mackichan at the Young Vic in Richard Jones's Government Inspector.
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MZ B cells also display a lower activation threshold than their FO B cell counterparts with heightened propensity for plasma cell differentiation that contributes further to the accelerated primary antibody response. In specimens where the tyrosine kinase for Pyk-2 has been knocked-out, marginal zone B-cells will fail to develop while B-1 cells will still be present. MZ B-cells are the only B-cells dependent on NOTCH2 signaling for proliferation. Marginal zone B cells are the malignant cells in marginal zone lymphomas, a heterogeneous group of generally indolent lymphomas.
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In 1995 they joined the first 'BratBus' NME tour with Veruca Salt, Marion and Skunk Anansie. After support spots with Oasis, Elastica and Dinosaur Jr., 60 Ft. Dolls released their second single "White Knuckle Ride" on Rough Trade Records and then "Pig Valentine" on the RCA imprint Indolent Records. These early singles were championed heavily by BBC Radio 1 DJ Steve Lamacq, and as a consequence were picked up by influential American DJ Rodney Bingenheimer of KROQ-FM. This resulted in the band signing a deal with Geffen Records in the USA.
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These immigrants were often the first Asians to be seen in British port cities and were initially perceived as indolent due to their reliance on Christian charities. Despite this, most early Pakistani immigrants married local white British women because there were few South Asian women in Britain at the time. During the colonial era, Asians continued coming to Britain as seamen, traders, students, domestic workers, cricketers, political officials and visitors, and some of them settled in the region. South Asian seamen sometimes settled after ill treatment or being abandoned by ship masters.
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The library's collection of materials features early purchases from Wilde's son Vyvyan Holland, the bibliographer Christopher Millard, and literary executor Robert Ross. This group of autograph letters and drafts by Wilde, supported by a nearly complete collection of printed editions of his works make useful research material for modern biographers. Original photographs, caricatures, theatre programs, and news cuttings are available. In looking over the material it can be seen that the image of the indolent Wilde, carefree and idle for much of the time, is misleading, although in some sense it is a myth that was perpetuated by the author himself.
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F. Andrews, 1853. > ... he experienced all the evils of insubordination among the troups, > perverseness in the militia, inactivity in the officers, disregard of > orders, and reluctance in the civil authorities to render a proper support. > And what added to his mortification was, that the laws gave him no power to > correct these evils, either by enforcing discipline, or compelling the > indolent and refractory to their duty ... The militia system was suited for > only to times of peace. It provided for calling out men to repel invasion; > but the powers granted for effecting it were so limited, as to be almost > inoperative.
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Not that Grant's concerns are in any way trifling. Her cast of characters is nothing less than a portrayal of post-war, class-riven Britain from the indolent aristocracy, to Oxford-educated blue stockings, and from car salesmen to the bottom of the pile, German émigrés and East End Jewish lowlifes." Overall, he decided that, "Grant writes well about illness as all who have read Remind Me Who I Am, Again can testify. This is a novel, above all, about trauma caused by the 'dark circle' of tuberculosis, and results in a 'tight circle' of comradeship.
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In 1930 he founded and presided over the Barcelona Philharmonic Society (Societat Filarmònica de Barcelona), an influential entity in the Barcelona musical atmosphere that programmed several concerts. His strong and demanding character and his indolent attitude towards the Franco regime made him, at the same time, loved and hated by the society of the moment; The impositions of the dictatorship prompted him to replace Catalan for a lifetime by the Spanish and to timidly approach the Franco regime in order to maintain his artistic activity throughout the country. He died in 1971 and was buried in the Cementiri de Montjuïc in Barcelona.
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In terms of the history of the Japanese tea ceremony, with the advent of the Tokugawa period in 1615, the fashion of samurai personally practicing chanoyu lost its attraction; chanoyu lost its function as a focal point for political ties among the samurai. From about the middle of the 18th century, however, the old-guard samurai who had scorned chanoyu as the idle game of indolent men of leisure had died. By this time, many of the new generation of daimyōs were rising as leaders in the development of urban culture. Matsudaira Harusato was outstanding among them.
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These infiltrations, which may involve the liver's bile ducts, often contained lymphoepithelial lesions. Immunohistochemistry testing of these tissues revealed lymphocytes that expressed CD20 and BCL-2 but not CD10 or cyclin D1. While optimal therapeutic strategies for this disease have not been established, primary hepatic EMZL appears to be an indolent cancer. Patients who underwent surgical resection with or without chemotherapy or rituximab treatment regimens and were observed over a median period of 31 months had mostly positive outcomes: 92% survived, 8% died of causes unrelated or only indirectly related to their cancer, and 11% suffered relapses.
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During his fifty years as master, Ewell—who was sometimes referred to as "Ole Marster" or "Ole Colonel of all"—created a fortune. Described as an eccentric "man of distinction and liberal fortune," Ewell was said to ride to Dumfries to tend to his business affairs on his "fiery black steed." He also served as the County Sheriff.Acts of the Commonwealth of Virginia, January 16, 1798 Although Ewell was known for his keen mental abilities and literary talent, he was apparently indolent and slow in movement, and even Thomas Jefferson needled him for not exercising his talents.
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Marcus Livius, the governor of the city, was a good soldier but is said to be a man of indolent and luxurious habits. On the night appointed by Hannibal for the attack he was feasting with friends and retired to rest, heavy with food and wine. In the middle of the night he was awakened when the conspirators blew the alarm on some Roman trumpets and found Hannibal and 10,000 of his soldiers already within the city. Many of the Roman soldiers were asleep or drunk and were cut down by the Carthaginians as they stumbled out into the streets.
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Cinematic was a stablemate of Beautiful Ammunition in that it was also created in the Survival Studios and under the Resolve label, yet demonstrated a further evolution in Borland's musical career. Despite being in a similar situation as regards funding, Cinematic benefited from much better, integrated production as well as punchy tracks such as "Bright White Light". With the psychological opener "Dreamfuel" a dream-like atmosphere pervaded the album, establishing itself in indolent, moody tracks like "Cinematic" and "When Can I Be Me?". It was, overall, a more coherent attempt than its predecessor, but – predictably – did not win over the public.
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Logan is the author of In the Nude, published in Nigeria by Ouida Poetry, 2019, and as Mannequin in the Nude by PANK Books in the USA. They are also the author of the chapbooks Painted Blue with Saltwater (Indolent Books, 2018). How to Cook a Ghost (Glass Poetry Press, 2017). Logan is a Pushcart and Best of the Net nominee and their poetry collection, Mannequin in the Nude was a finalist for in the 2018 African Poetry Book Fund and was also listed in one of the top fifteen debut book in Nigeria by Brittle Paper.
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"Edward Askew Sothern", Virtual American Biographies (2001) The Athenaeum wrote, "it is certainly the funniest thing in the world... a vile caricature of a vain nobleman, intensely ignorant, and extremely indolent".The Athenaeum, 16 November 1861 Dundreary became a popular recurring character, and Sothern successfully revived the play many times, making Dundreary by far his most famous role. A number of spin-off works were also created, including Charles Gayler's sequel, Our American Cousin at Home, or, Lord Dundreary Abroad (Buffalo, New York, 1860,Buffalo Daily Courier, 1 November 1860 and then New York City, 1861Brown, T. Allston (1903).
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The best treatment for MBA in individuals with an EBV+ LPD vaires. Mild and clearly uncomplicated cases with, for example, indolent CAEV, are treated conservatively focusing on obtaining relief of symptoms such as skin irritation, fever, and malaise. Cases with evidence of significant complications of CAEFV such as the development of hemophagocytosis, NK/T cell lymphoma, or aggressive NK cell lymphoma generally require chemotherapeutic regimens directed at these complications. Individuals with EBV+ systemic MBA and clear evidence of concurrent aggressive CAEBV have been treated with relative success by the 3 step regimen used to treat CAEBV.
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In 1831, Sydney is a frontier town, full of rough ex-convicts from the British Isles. The new Governor, Sir Richard (Cecil Parker), arrives with his charming and cheery but indolent second cousin, the Honourable Charles Adare (Michael Wilding). Charles, who is hoping to make his fortune, is befriended by gruff Samson Flusky (Joseph Cotten), a prosperous businessman who was previously a transported convict, apparently a murderer. Sam says that, because he has bought the legal limit of land, he wants Charles to buy land and then sell it to him for a profit so that Sam can accumulate more frontier territory.
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Great Britain: Edward Elgar, 2010. Print Smith had misgivings concerning some aspects of each of the major character-types produced by modern capitalist society, namely the landlords, the workers and the capitalists. Smith claimed that "[t]he landlords' role in the economic process is passive. Their ability to reap a revenue solely from ownership of land tends to make them indolent and inept, and so they tend to be unable to even look after their own economic interests" and that "[t]he increase in population should increase the demand for food, which should increase rents, which should be economically beneficial to the landlords".
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Born in Chichester, Sussex, the son of a hatmaker and former mayor of the town, Collins was educated at The Prebendal School, Winchester and Magdalen College, Oxford. While still at the university, he published the Persian Eclogues, which he had begun at school. After graduating in 1743 he was undecided about his future. Failing to obtain a university fellowship, being judged by a military uncle as 'too indolent even for the army', and having rejected the idea of becoming a clergyman, he settled for a literary career and was supported in London by a small allowance from his cousin, George Payne.
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This development conforms to the meaning of Article 13 of the UN Charter which requires the initiation of studies and recommendations encouraging the "progressive development of international law." A third path employ: regional cooperation schemes to build regional unified spaces "based on common political and legal principles, norms and values. This points out to a shift of emphasis from grandiose global codification efforts to more promising and less indolent regional arrangements.” Against this background, he argued that "the bountiful miscellany of arms control agreements provide a vast resource, for monitoring all the above courses of development in international law.
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Frederick William II (; 25 September 1744 – 16 November 1797) was King of Prussia from 1786 until his death. He was in personal union the Prince-elector of Brandenburg and (via the Orange-Nassau inheritance of his grandfather) sovereign prince of the Canton of Neuchâtel. Pleasure-loving and indolent, he is seen as the antithesis to his predecessor, Frederick II. Under his reign, Prussia was weakened internally and externally, and he failed to deal adequately with the challenges to the existing order posed by the French Revolution. His religious policies were directed against the Enlightenment and aimed at restoring a traditional Protestantism.
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Regardless of the type of presentation, FL is usually (~80% of cases) at an advanced stage at diagnosis as indicated by involvement of the bone marrow (50% to 70% of cases), multiple lymph nodes in different parts of the body, and/or other tissues. A minority (<33%) of FL patients present with B symptoms, i.e. recurrent unexplained fevers, recurrent night sweats, and/or weight loss ≥10% in the past 6 months. Generally, the disease has an indolent and prolonged course with a median life expectancy of 15–20 years: a large percentage of patients die from other causes than their FL disease.
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More recently, 36 patients have been treated with surgical resection alone followed by observation; all these patients survived with only one having a relapse. Thus, PTFL appears to be a highly indolent type of FL in which multiple studies have reported overall and progression-free survival rates of 100% and >90%, respectively, for >2 years and an estimated probability of 5-year event-free survival rate of ~96%. The therapeutic regimens versus follow-up observations that best treat this disorder in children, adolescents, and adults (adults may require different treatments than children and adolescents) requires further study.
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Wilhelm Ebstein introduced the term "acute leukemia" in 1889 to differentiate rapidly progressive and fatal leukemias from the more indolent chronic leukemias. The term "myeloid" was coined by Franz Ernst Christian Neumann in 1869, as he was the first to recognize white blood cells were made in the bone marrow (Greek: , ', ) as opposed to the spleen. The technique of bone marrow examination to diagnose leukemia was first described in 1879 by Mosler. Finally, in 1900, the myeloblast, which is the malignant cell in AML, was characterized by Otto Naegeli, who divided the leukemias into myeloid and lymphocytic.
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In Anna's day, too, there was much to be said for promulgating an official version of England's queen dying 'respectably'." Barroll, 172; A letter from Anne to Scipione Borghese of 31 July 1601 is "open in its embrace of Catholicism", according to McManus, 93. Historians have traditionally dismissed Anne as a lightweight queen, frivolous and self-indulgent. Agnes Strickland (1848), 276 Retrieved 10 May 2007; Willson, 95; "Her traditionally flaccid court image ..." Barroll, 27; Croft, 55; "Anne had proved to be both dull and indolent, though showing a certain tolerant amiability so long as her whims were satisfied.
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Apparently an indolent student, he was tutored by Mandell Creighton during the vacations and managed a second class in Honour Moderations. He subsequently became more idle, using his time to become university champion at real tennis. In 1882 his grandfather died and he inherited a baronet's title, an estate of about , and a private income. Returning to Oxford in the autumn of 1883, Grey switched to studying jurisprudence (law) in the belief that it would be an easier option, but by January 1884 he had been sent down but allowed to return to sit his final examination.
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Entranced by Eugenie's beauty, Bonaparte arranges for his romantic rival to be assigned to a diplomatic post in Egypt, joining his father, Count Mathieu de Lesseps (Henry Stephenson), the Consul-General. De Lesseps impulsively asks Eugenie to marry him immediately, but she turns him down. In Egypt, de Lesseps befriends two people who will have a great influence on his life: Toni Pellerin (Annabella), a tomboy being raised by her grandfather, French Sergeant Pellerin (Sig Rumann); and Prince Said (J. Edward Bromberg), the indolent heir of his father, Mohammed Ali (Maurice Moskovitch), the Viceroy (ruler) of Egypt.
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For the crew's exercise and entertainment, he introduced regular music and dancing sessions. Bligh's despatches to Campbell and Banks indicated his satisfaction; he had no occasion to administer punishment because, he wrote: "Both men and officers tractable and well disposed, & cheerfulness & content in the countenance of every one". The only adverse feature of the voyage to date, according to Bligh, was the conduct of the surgeon Huggan, who was revealed as an indolent, unhygienic drunkard. From the start of the voyage, Bligh had established warm relations with Christian, according him a status which implied that he was Bligh's second-in-command rather than Fryer.
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The book remains the most widely read work of older Czech literature. The world is portrayed as a city which resembles a labyrinth, entered by a pilgrim (the narrator and author himself). The city has The Gate of Entering, and The Gate of Separation; six main streets which represent the six classes of the world; The Castle of Fortune in its middle; and The Common Square. In Part One of the book, Labyrinth of the World (Chapters 1–36), the pilgrim is joined by two guides, Searchall Ubiquitous (allegory of human curiosity and longing for knowledge), and Delusion (allegory of indolent adopting of conventional and shallow thoughts).
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To the same kind patron may be ascribed his selection as deputy-adjutant-general to the garrison of Menorca. This appointment prevented his accompanying the expedition to Egypt, where his patron was killed; but his activity and real merit soon won him a powerful friend in the influential General Henry Fox, the brother of the orator, and at this time governor and commander-in-chief in Menorca. The somewhat indolent general liked to have such an energetic man to save him trouble, and took him as military secretary to Ireland, when he was appointed commander-in-chief there in 1802. He there married the Hon.
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At the time of her second marriage, she was a rich widow and Jerome heavily indebted, and the marriage enabled him to pay his debts and continued his luxurious lifestyle in Florence. It was a morganatic marriage upon the request of Jerome, who did not wish to recognize her officially and insisted upon calling her Madame la Marquise and have her referred to as such by others. Baron du Casse described her as beautiful, distinguished, sweet and interested in charity, but also as indolent and languid in her habits. She followed Jerome to France in 1847, and resided with him in Paris with his son.
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PTFL differs from follicular lymphoma in its clinical manifestations, its pathophysiology including the genomic alterations (i.e. chromosome abnormalities and gene mutations) which occur in the diseases malignant cells, and its clinical course. Relative to the last point, PTFL often presents histologically as a high-grade malignancy but unlike the small percentage of follicular lymphoma cases that similarly present as a high grade malignancy, it almost invariably takes an indolent, relapsing and remitting course without progressing to a more aggressive and incurable form. Recognition of PTFL as a distinct disease separate from follicular lymphoma is critical to avoid mistaking it for a more aggressive lymphoma that requires potentially toxic chemotherapy treatments.
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A diagnostic gene signature serves as a biomarker that distinguishes phenotypically similar medical conditions that have a threshold of severity consisting of mild, moderate or severe phenotypes. Establishing verified methods of diagnosing clinically indolent and significant cases allows practitioners to provide more accurate care and therapeutic options that range from no therapy, preventative care to symptomatic relief. These diagnostic signatures also allow for a more accurate representation of test samples used in research. Similar to the procedure of validation of prognostic gene signature, a criterion exists for classifying a gene signature as a biomarker for a disorder or diseases outlined by Chau et al.
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Though most reports describe Berger's disease as having an indolent evolution towards either healing or renal damage, a more aggressive course is occasionally seen associated with extensive crescents, and presenting as acute kidney failure. In general, the entry into chronic kidney failure is slow as compared to most other glomerulonephritides – occurring over a time scale of 30 years or more (in contrast to the 5 to 15 years in other glomerulonephritides), however in aggressive Berger's disease the time scale is within 5–10 years and often sooner. This may reflect the earlier diagnosis made due to frank hematuria. Complete remission of aggressive Berger's disease, occurs rarely in adults.
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According to film historian and critic David Thomson, Douglas was capable of playing characters who were "weak, culpable, morally indolent, compromised, and greedy for illicit sensation without losing that basic probity or potential for ethical character that we require of a hero".Thomson, David. The New Biographical Dictionary of Film, Alfred A. Knopf (2002) pp. 247–249 Critic and author Rob Edelman points out similarities in many of Douglas's roles, writing that in some of his leading films, he personified the "contemporary, Caucasian middle-to-upper-class American male who finds himself the brunt of female anger because of real or imagined sexual slights".
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She was sometimes described as dull and indolent, but usually as vivacious and decided: it was said of her that she "knew how to exact obedience and to get her own way", and she was generally considered as quite charming and a "pleasing, piquant and intelligent personality". In February 1739, when she was eleven years old, her engagement to the Infante Philip of Spain was announced. Philip was the third son of Louis XV's uncle, Philip V d'Anjou, King of Spain, and Elizabeth of Parma. This engagement followed a tradition dating back to 1559 of cementing military and political alliances between the Catholic powers of France and Spain with royal marriages.
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In The Orangerie (1796), James Gillray caricatured William's dalliances during his exile, depicting him as an indolent Cupid sleeping on bags of money, surrounded by pregnant amours William V joined the First Coalition against Republican France in 1793 with the coming of the French Revolution. His troops fought bravely in the Flanders Campaign, but in 1794 the military situation deteriorated and the Dutch Republic was threatened by invading armies. The year 1795 was a disastrous one for the ancien régime of the Netherlands. Supported by the French Army, the revolutionaries returned from Paris to fight in the Netherlands, and in 1795 William V went into exile in England.
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Warren and Brandeis take this opportunity to excoriate the practices of journalists of their time, particularly aiming at society gossip pages: > The press is overstepping in every direction the obvious bounds of propriety > and of decency. Gossip is no longer the resource of the idle and of the > vicious, but has become a trade, which is pursued with industry as well as > effrontery. To satisfy a prurient taste the details of sexual relations are > spread broadcast in the columns of the daily papers. To occupy the indolent, > column upon column is filled with idle gossip, which can only be procured by > intrusion upon the domestic circle.
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Large B-cell lymphoma with IRF4 rearrangement (LBCL with IRF4 rearrangement) is a DLBCL in which tissue infiltrates containing intermediate- or large-sized neoplastic B-cells strongly express a chromosomal translocation involving the IRF4 gene on the short arm of chromosome 6. These cells form follicular, follicular and diffuse, or entirely diffuse infiltrates in Waldeyer's tonsillar ring or other regions of the head and neck. The disease, which represents ~0.05% of all DLBCL, occurs primarily in children and young adults and typically has a good prognoses. Cases with a follicular pattern of tissue infiltrates often have indolent disease and an excellent prognosis following excision and may not need chemotherapy.
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His skull measurements (by volume) then came to serve as "evidence" for racial stereotypes. He described the Caucasian as "distinguished by the facility with which it attains the highest intellectual endowments"; Native Americans were described as "averse to cultivation, and slow in acquiring knowledge; restless, revengeful, and fond of war, and wholly destitute of maritime adventure" and the Africans he described as "joyous, flexible, and indolent; while the many nations which compose this race present a singular diversity of intellectual character, of which the far extreme is the lowest grade of humanity".Menand, L. (2001). Morton, Agassiz, and the origins of scientific racism in the United States.
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In general, cronopios are depicted as naive and idealistic, disorganized, unconventional and sensitive creatures, who stand in contrast or opposition to famas (who are rigid, organized and judgmental if well-intentioned) and esperanzas (who are plain, indolent, unimaginative and dull). In his stories Cortázar describes few physical features of cronopios. He does refer to them (in one of the early stories Costumbres de los famas) as "those greenish, frizzly, wet objects," but this description is just the initial author's vision of the invented character. In a letter to Paul Blackburn on 1959-03-27 Cortázar writes that human characteristics of cronopios appeared later, while writing other stories.
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According to Don Whitington, McMahon's life before entering politics was "the aimless, indolent existence of a wealthy young man with a position in a big city's smart set, no positive ambition or even interests, except in enjoying himself, and no family ties to give him a feeling of responsibility or even consideration for others".Whitington (1972), p. 147. After graduating from university, he secured a position as a solicitor with Allen, Allen & Hemsley, a major Sydney law firm; he was made a junior partner in 1939. He was assigned to the Commonwealth Bank and the Bank of New South Wales for periods, which helped spark his interest in economics.
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He worked under first Ernst Schimmelmann and then Johan Sigismund von Møsting. From early in his career, Collin had thoughts about a fundamental reorganization of the central administration. In 1815 he anonymously published as short article in Minerva in which he mocked the indolent and incompetent civil servants who only thought of their work as long as they were in their offices instead of "bringing it along wherever they go, going to bed with it at night and getting up with it in the morning". In the same articles, he proposed to place the responsibility for the government's government spending and incomes in a single department.
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Like its City counterpart, the Westminster Bridewell was intended as a "house of correction" for the compulsory employment of able- bodied but indolent paupers. Built in 1618, it was enlarged in 1655, and during the reign of Queen Anne, its regime was extended to cover the incarceration of criminals. In 1834 the original Bridewell was replaced by a larger prison, on a different site, in area, south of Victoria Street and close to Vauxhall Bridge Road. The new prison, designed by Robert Abraham and costing £186,000, was circular in plan (following Jeremy Bentham's "panopticon"), so that warders could supervise prisoners from a central point, and had a capacity of 900 prisoners.
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The disorder was regarded as a subtype of follicular lymphoma termed primary intestinal follicular lymphomas or Primary gastrointestinal tract follicular lymphomas. However, follicular lymphomas of the duodenum and other parts of the small intestine differ from the other forms of primary intestinal lymphomas in that they are indolent, highly localizes disorders that have a low rate of progression to a systemic disease. In consequence, the World Health Organization (2017) kept the more widespread primary intestinal lymphomas within the follicular lymphoma category and reclassified duodenal-/small intestinal-localized lymphoma as a distinct disease entity, DFL. DFL, while currently considered a malignant disease, has many clinical features which are more similar to the benign predecessor of follicular lymphomas viz.
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Rosa himself may have dismissed them as frivolous capricci in comparison to his other themes, but these academically conventional canvases often restrained his rebellious streak. In general, in landscapes he avoided the idyllic and pastoral calm countrysides of Claude Lorrain and Paul Bril, and created brooding, melancholic fantasies, awash in ruins and brigands. By the eighteenth century, the contrasts between Rosa and artists such as Claude was much remarked upon. A 1748 poem by James Thompson, "The Castle of Indolence", illustrated this: "Whate'er Lorraine light touched with softening hue/ Or savage Rosa dashed, or learned Poussin drew".Lines from "The Indolent Castle", James Thompson, 1748 quoted by Helen Langdon in Burlington Magazine 115(84):p.
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The Unseen University (UU) is a school of wizardry in Terry Pratchett's Discworld series of fantasy novels. Located in the fictional city of Ankh- Morpork, the UU is staffed by a faculty composed of mostly indolent and inept old wizards. The university's name is a pun on the Invisible College, and many aspects of the University are references to Oxford and Cambridge University. The exploits of the head wizards of the Unseen University are one of the main plot threads in the long-running fantasy series, and have played a central role in 13 novels to date, as well as the four supplementary Science of Discworld novels and the short story, A Collegiate Casting-Out of Devilish Devices.
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Among the things provided by the home were a library of Christian books in Asian and African languages, a store room for valuables, and a place where Lascars could send their earnings back to India. Lascars were allowed entrance as long as they had the prospect of local employment, or were on a ship returning East. The collective naming of these groups as "strangers" reflects British attitudes at the time. Lascar immigrants were often the first Asians to be seen in British cities and were initially perceived as indolent due to their reliance on Christian charities. In 1925 the Coloured Alien Seamen Order 1925 Act was brought into law by the Secretary of State for the Home Department.
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Sandow is jolted from his wealthy, indolent lifestyle by a series of messages, each accompanied by a picture of one of a number of people once important to him, and all dead for many years. Sandow realizes the pictures could be fake, and he has other obligations, one of which is responding to a call for help from a friend, Ruth Laris. In the course of investigating her disappearance, he receives another message that he will find all his friends "on the Isle of the Dead". The message is in Pei'an, addressed to Shimbo (the name of the Pei'an god connected with Sandow) and signed by Belion (Shimbo's traditional enemy in Pei'an mythology).
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Exceptions are chorea and indolent carditis, each of which by itself can indicate rheumatic fever. An April 2013 review article in the Indian Journal of Medical Research stated that echocardiographic and Doppler (E & D) studies, despite some reservations about their utility, have identified a massive burden of rheumatic heart disease, which suggests the inadequacy of the 1992 Jones' criteria. E & D studies have identified subclinical carditis in patients with rheumatic fever, as well as in follow-ups of rheumatic heart disease patients who initially presented as having isolated cases of Sydenham's chorea. Signs of a preceding streptococcal infection include: recent scarlet fever, raised antistreptolysin O or other streptococcal antibody titre, or positive throat culture.
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Follicular lymphoma generally presents with an indolent course, some patients do not need treatments for several years, while others whose cancer has widely spread to lymph nodes or organs need treatment immediately. In some cases, the disease can transform into an aggressive type of lymphoma, mostly diffuse large B-cell lymphoma (DLBCL). Patients who have stage I or II FL may be closely monitored without receiving treatment, they may be treated with radiation therapy alone or with chemotherapy. Patients who are in stage II but have bulky disease, in stage III/IV or have relapsed or refractory disease may be treated with therapies depending on the patient's age, overall health, disease progression, symptoms, and the patient's choice.
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There have been numerous biographies about Lillie Langtry, (she also wrote her own autobiography) but little has been written about her first husband Edward (Ned) Langtry. What has been written often paints him in a negative light. He has been referred to as "a colourless sportsman"; "a pudgy chap, his weak mouth overhung with a walrus moustache, and his conversation powers were limited"; "petulantly determined on his own importance......he was weak and indolent and also, surprisingly shy"; "a meek, weak husband and no money";"uneasily complaisant husband". If these descriptions are accurate, it is difficult to understand why a woman as gifted as Lillie would marry a man with such shortcomings.
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The wives' power plays are directly correlative to their husbands' positions in the company (meaning, the higher-ranking the husband, the higher-ranking the wife), and Ji-ae sets aside her pride to curry favor and jockey for position. She immediately thrives within the wives' inner circle, but she's constantly thwarted by her ex-best friend, Bong-soon. Then Dal-soo runs into his college friend Eun So-hyun (Sunwoo Sun), wife of Heo Tae-joon (Yoon Sang-hyun), the current president of Queen's Food. Stuck in a loveless marriage, So-hyun wants to have an affair with Dal-soo, while indolent chaebol Tae-joon gradually finds himself attracted to Ji-ae.
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He tried his hand as a lyricist in such works as His Majesty, a comic opera in the Gilbert and Sullivan vein, with music by Alexander Mackenzie, a libretto by F. C. Burnand and additional lyrics by Adrian Ross, presented at the Savoy Theatre in 1897.The Whitehall Review, 27 February 1897 He was editor of the Daily News in 1901. In 1906 Lehmann was elected Member of Parliament (MP) for Harborough which he held until 1910. He was sketched in A History of Punch by R.G.G. Price as indolent, but able to rouse to write a short piece, and as having given some of that character to the rest of the staff.
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Register, 5 January 1839 Tall and lanky, the strong and courageous Inman was an active and effective field commander, personally leading many investigations in the pursuit of bushrangers and other offenders. He set a strong Christian moral tone, such that none of the police were indolent or corrupt. However, he was such a disappointment as an administrator and financial manager that Gawler appointed a four-man Board of Police Commissioners in December 1839 to ensure oversight of the force. That same month, Inman accompanied Gawler and Sturt on a Murray River expedition, during which they discovered Mount Bryan, naming it after Henry Bryan, a fellow expeditioner who became lost and then perished.
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The force still met little resistance save for a few confused policemen who initially refused to let the leader of the Edison force into the town hall. Meanwhile, the council was informed of the insolence of the Edison force; they scrambled to put together a segment of the Militia headed by Creek General Onetiwa to stop any further action on the part of the Edison force. The two small armies met outside of Leary on May 12, where many among the indolent band from Edison were rallying to push on the large settlement of Albany. General Onetiwa met privately with the leader of the Edison force, James Walters, who was the mayor of Edison.
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The first and last parts of the novel are set in Tep's Town, on the site of modern Los Angeles. The town consists of three classes: the Lords, the ruling class, who live in a separate area of the town; the kinless, essentially a slave class forbidden to carry weapons, descendants of a people conquered by the allied ancestors of the Lords and the Lordkin; and the Lordkin, proud, uneducated, undisciplined and indolent knife fighters organised into street gangs, who live by "gathering" whatever they wish from the kinless. The Lords supervise the kinless and placate the Lordkin. The kinless are unarmed and untrained in the use of weapons, and cannot resist the Lordkin.
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An unmet need is to identify the relatively small proportion of men with a lethal phenotype in whom death can be prevented by curative intervention, while avoiding treatment of the large pool of indolent disease that can be detected with screening. Selection of patients for active surveillance depends upon patient and tumor metrics, as well as a patient's personal preferences. The age, comorbidities, and estimated life expectancy of the patient are important to consider given that prostate cancer can be a slowly progressive disease that may not have time to progress in those whose remaining years of life are limited. In this respect, tools for estimating life expectancy can be useful in decision making.
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By 1908, much of the vigor and determination that went into the organization of the Association gradually died out due to a combination of internal and external complications. Most notably, the unfavorable land tenure system, the indolent and indifferent farmer, financial inability, and trust opposition all succeeded in the delay of progressive action. One of the most discouraging obstacles that the Association faced was the independent farmer who asserted his independence by refusing to join the association. These nonmembers, or "hillbillies," believed a better price could be obtained by refusing to join the association, and, in many instances, actually succeeded in obtaining significantly higher prices from the ATC representatives due to the shortage of tobacco.
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ENKTCL-NT can be mimicked by two benign diseases which involve the excessive proliferation of non-malignant NK cells in the GI tract viz., Natural killer cell enteropathy, a disease wherein NK cell infiltrative lesions occur in the intestine, colon, stomach, and/or esophagus, and lymphomatoid gastropathy, a disease wherein these cells infiltrative lesions are limited to the stomach. Another lymphoproliferative disorder of the GI tract, indolent T cell lymphoproliferative disorder of the gastrointestinal tract may also mimic ENKTCL-NT. This chronic disorder involves the proliferation of CD+4, CD8+, CD4-/CD8-, or CD4+/CD8+ T cells in the mucosal layers of the GI tract to give a variety of GI tract symptoms.
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However, now only nine springs are known of which the popular one is Hercules spring, which emanates from fissures. The temperature of the water, on an average, remains in the range of 70 to 145 0 F. The nine different springs in use have varying degree of chemical content with the usual sulphurated hydrogen gas, lime sulphate, soda and lime, nitrogen gas, carbonic acid gas. However, the Hercules bath does not contain sulphurated hydrogen. The temperature is controlled through a cooling apparatus. Eye treatment is also arranged with the spring water, apart from the therapeutic healing powers for scrofula, joint pains, chronic rheumatism, gout, indolent skin diseases, complicated mercurial afflictions, hysteria, hypochondria ad many other “opprobria medica”.
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Despite what was planned, the hospital wasn't functioning well in the beginning. In the end, it turned out to have less space and air per patient than envisioned, ventilation wasn't good as "it wasn't working when it was most needed", administration was incomplete and indolent while the medics were understaffed ultimately providing sub-standard care. The hospital had no pharmacy of its own and work of the doctors was hampered by the mandatory police supervision of the hospital. Some doctors were so dissatisfied with the hospital, that doctor Vladan Đorđević said: "[The building is] so unbound, but only one nice side of it - the building is easy on the eye and had magnificent gates and staircase".
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She then stepped into Fathimath Nahula's critically and commercially successful romantic drama television series, Kalaage Haqqugaa to portray the role of Aishath Imna, a sacrificing mother and an orphan who was later abandoned by her guardian. She rose to widespread prominence in the television industry with her performance as an indolent daughter who marries her best-friend in the Arifa Ibrahim-directed critically acclaimed television series, Vairoalhi Ahves Sirrun (2005) which revolves around two best-friends involved in extra-marital affairs and who fail to practice their duty as husband and wife. Starring alongside Lufshan Shakeeb, Ahmed Asim, Aminath Rasheedha and Mariyam Shakeela, the series was listed as one of the most successful television series.
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Gothelo II (also Gozelo) (1008–1046), variously called the Coward, the Sluggard, the Indolent, or the Lazy (Latin ignavus), has been often said to be Duke of Lower Lorraine after the death of his father Gothelo I, Duke of both Lower and Upper Lorraine (1044) until his own death in 1046. When Gothelo I died in 1044, Godfrey III, his eldest son, who had been co-ruling in Lower Lorraine for several years, was not given Lower Lorraine by the Emperor Henry III. Henry first threatened to give Lower Lorraine to the second son Gothelo (not known for his courage or competency and who was perhaps mentally deficient). Godfrey rebelled and was imprisoned.
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Duodenal-type follicular lymphoma (DFL) is a form of lymphoma in which certain lymphocyte types, the B-cell-derived centrocytes and centroblasts, form lymph node follicle-like structures principally in the duodenum and other parts of the small intestine. It is an indolent disease which on rare occasions progresses to a more aggressive lymphoma that spreads beyond these originally involved sites. The disorder now termed DFL had been considered to be a follicular lymphoma that develops in one or more sites of the GI tract (i.e. stomach, duodenum, jejunum, small intestine, large intestine and rectum) as well as in various sites outside of the GI tract; this contrasts with other forms of follicular lymphoma which do not involve the GI tract.
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Early instances of Hispanophobia arose as the influence of the Spanish Empire and the Inquisition spread through late-medieval Europe. During this period Hispanophobia materialized in folklore which is sometimes referred to as the Black Legend: La leyenda negra, as Spanish historians first named it, entailed a view of Spaniards as "unusually cruel, avaricious, treacherous, fanatical, superstitious, hot-blooded, corrupt, decadent, indolent, and authoritarian". As Spain and England colonized the Americas, "[t]he Black Legend informed Anglo Americans' judgments about the political, economic, religious, and social forces that had shaped the Spanish provinces from Florida to California, as well as throughout the hemisphere". These judgments were handed down from Europeans who saw the Spaniards as inferior to other European cultures.
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Back at headquarters, Sharpe is informed by Major Michael Hogan that the Real Compania Irlandesa, the royal bodyguard of the captive King of Spain, have been sent to join Wellesley's forces. As the British wish for Wellesley to be appointed Generalissimo of the Spanish Armies, it is imperative that the unwanted soldiers be treated with honour, though they are composed of Irish exiles and their descendants (who have no love for the British due to their occupation of Ireland) and have no combat experience. Wellesley assigns Sharpe to encourage them to desert by taking them to a fort close to the French and drilling them mercilessly. There Sharpe also has to deal with former Wagon Master-General Colonel Claude Runciman, a grossly fat and indolent man.
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The three MZL subtypes occur more often in older people (age 65–68 years) and are indolent diseases that may in people without symptoms asymptomatic be initially treated by a watchful waiting strategy. However, NMZL carries a somewhat worse long term outcome than the other subtypes and any of the MZL subtypes may progress in a low percentage of cases to a more aggressive lymphoma, particularly diffuse large B-cell lymphoma. One of the most distinctive feature of MZL is that many cases are associated with the persistent simulation of the immune system by the chronic inflammation that accompanies infections or autoimmune diseases. MZL cases associated with certain infectious pathogens can be cured by treatment directed at the pathogens causing or associated with these infections.
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Helicobacter pylori is the bacteria that often causes gastric ulcers and is a main cause of primary gastric EMZL Primary gastric EMZL, also termed primary gastric MALT lymphoma or, more often, just gastric MALT lymphoma, is usually an indolent disease that in ~10% of cases also involves other GI tract and/or non-GI tract sites. Patients commonly present at an early stage of the disease with various symptoms such as nausea, vomiting, indigestion, upper abdominal pain, and gastric bleeding as indicated by coughing up blood, bloody bowel movements, and/or iron deficiency anemia. Rarely, patients present with perforation of the stomach or B symptoms such as fever and night sweats. Individuals with chronic Helicobacter pylori infection may also have halitosis.
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Brooks stayed at a pension in Heidelberg in 1890, where he formed a close relationship with the young Somerset Maugham. His relationship with Maugham was significant both as Maugham's first sexual experience and for forming his literary tastes: The character Hayward in Maugham's Of Human Bondage, an "esthete who is just back from Germany and admires Pater" and influences Philip, the young protagonist, is "obviously based on Ellingham Brooks". Five years later, Maugham and Brooks would cross paths again in Capri: Maugham disapproved of Brooks' indolent life in Capri, and based the protagonist of an unflattering short story, The Lotus-Eater, on him. In The Summing Up, Maugham called Brooks "Brown"Robert Calder, Willie: The Life of W. Somerset Maugham, p.
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However, this results in hypoxia, so the fenestration may eventually need to be closed by an interventional cardiologist. In a 2016 review, Dr. Jack Rychik, head of the Single Ventricle Survivorship Program at Children's Hospital of Philadelphia summarized the long-term consequences of Fontan circulation as an "indolent and progressive state of heart failure" with predictable long term consequences on several organ systems. Chronic venous hypertension and lowered cardiac output are assumed to be at the root of lymphatic complications such as chylothorax, protein losing enteropathy and plastic bronchitis which may occur in the immediate post-operative period as well as in the medium term. New interventional and surgical strategies have been investigated to relieve the lymphatic complications associated with the Fontan circulation.
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FM in the context of chemotherapy means a chemotherapy regimen used as first- line therapy in indolent lymphomas. In combination with rituximab it is called R-FM or RFM or FM-R or FMR. The [R]-FM regimen consists of: # (R)ituximab - an anti-CD20 monoclonal antibody that is able to kill both normal B cells and malignant ones; # (F)ludarabine - an antimetabolite; # (M)itoxantrone - a synthetic anthracycline analogue (an anthraquinone) that is able to intercalate DNA and prevent mitosis.Fludarabine Plus Mitoxantrone With and Without Rituximab Versus CHOP With and Without Rituximab As Front-Line Treatment for Patients With Follicular Lymphoma This regimen is also sometimes used in some autoimmune disorders that are inherently sensitive to rituximab, fludarabine and mitoxantrone in monotherapies (e.g.
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In fine weather, especially in the autumn when the chincopin nuts were ripe we found it hard to abandon the horses so instead we abandoned school along with similarly inclined friends also mounted and sped towards the Potomac river and its heavily forested banks. We spent the days swimming and speculating what we would do with the rest of our indolent lives.' :As the Second World War was in full swing, no one paid attention to our lack of reading or writing skills. As long as we were up in time to milk the cows, make sandwiches for lunch and were off on the horses in the direction of school our Mother was too pre-occupied with her war work to notice our pristine exercise books.
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The Ironheads nearly successfully start a riot when Beddle castigates Dr. Leving after one of her lectures on the nature of robots and how they affect human beings. It is her thesis that the superabundance of robotic labor has caused humans to become indolent and nearly incompetent at accomplishing even trivial tasks. She also claims that robots themselves do not qualify as a very good successor to humanity given that their sole purpose is to serve humans. It is revealed that some members of Leving Labs have both personal and professional secrets to hide: Gubber Anshaw is romantically involved with Tonya Welton, while Jomaine Terach is aware of the creation of Caliban and the fact that he lacked the Three Laws of Robotics.
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Renée, who conceals her true self to conform to the lowly image of typical concierges, introduces herself as "a widow, short, ugly, chubby", with "bunions on my feet and, on certain difficult mornings, it seems, the breath of a mammoth". Her outward appearance is summarized by The Guardian reviewer Ian Samson as "prickly and bunioned". When Paloma eventually discovers Renée's identity, she describes the latter in her journal as having the "elegance of the hedgehog"—although like the spines of the hedgehog, she is covered in quills and prickly, within, she has in the words of the English translation of the book quoted by Viv Groskop "the same simple refinement as the hedgehog: a deceptively indolent little creature, fiercely solitary—and terribly elegant".
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Naturally vacillating and indolent, Wladislaw had not the force to withstand the determination of the great Hungarian nobles to rule, and the royal power became the plaything of the various parties. The antagonisms of the different ranks of society grew more acute and led, in 1514, to a great peasant revolt, directed against the nobles and clergy, which was only suppressed after much bloodshed. The Diet of 1498 passed enactments correcting the ecclesiastical abuses that had become prevalent during the reign of Matthias and prohibited particularly the appointment of foreigners to ecclesiastical positions. Among other enactments were those that forbade the granting of church offices to any but natives, the holding of ecclesiastical pluralities, and the appropriation of church lands by the laity.
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Dark Cloud began working for American Mutoscope and Biograph in New York City in 1910, making his first screen appearances in the era of "eastern Westerns" under the direction of D. W. Griffith and with cinematography by Billy Bitzer. Unlike the later Westerns, featuring dramatic conflicts and indolent Natives, these early films showed Native Americans with respect: in serene, nearly still-life profile against a wide landscape, as though in calm reflection on their lives before the treaties were broken.Scott Simmon, The Invention of the Western Film: A Cultural History of the Genre's First Half-century, Cambridge University Press (2003), p. 17. The Song of the Wildwood Flute, with Mary Pickford and Mack Sennett, was filmed near Fishkill, New York.
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The combination of lenalidomide with rituximab has shown good potential in treating indolent cases of FL. Studies indicate that maintenance therapy with rituximab following successful induction therapy prolongs progression-free survival; for example one study found progression-free survival after 6 years of treatment was 59.2% in patients treated with rituximab maintenance and 42.7% without this maintenance; however, overall survival at 6 years was similar in the two groups, 87.4% and 88.7%, respectively. Another study found that prolonged maintenance with rituximab did not have any benefits over an eight-month maintenance period. Finally, surgery and radiation are additional therapies that can be used to relieve symptoms caused by bulky t-FL disease or to treat lesions in patients who cannot withstand other types of treatment.
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Louis XIV, too, had a low opinion of his son: : indolent, fatuous, and dull, only the saving grace of his bourgeois morals kept him from outraging the pious people about him. Like his father he enjoyed the hunt, but that was about the only way in which this disappointing son resembled his father. John B. Wolf, Louis XIV (1968) p 606 Alive especially to political considerations, the King considered various European royal daughters as possible wives for his heir, such as Anna Maria Luisa de' Medici, Louis' own cousin Marie Louise d'Orléans, daughter of Philippe, Duke of Orléans, and Princess Henrietta of England. According to various reports, Marie Louise and Louis were in love, having grown up with each other.
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This is because a very large proportion of such cases will not progress to kill the patient, and thus mammography cannot be genuinely claimed to have saved any lives in such cases; in fact, it would lead to increased sickness and unnecessary surgery for such patients. Consequently, finding and treating many cases of DCIS represents overdiagnosis and overtreatment. Treatment is given to all women with DCIS because it is currently impossible to predict which patients with DCIS will have an indolent, non-fatal course, and which few will inevitably progress to invasive cancer and premature death if left untreated. Consequently, all patients with DCIS are treated in much the same way, with at least wide local excision, and sometimes mastectomy if the DCIS is very extensive.
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The film revolves around a woman who has been mistreated by her step-mother and forced into a marriage she disapproves. Abbas played the role of Lillian, an indolent daughter who ill-treats her own mother. She rose to widespread prominence in the television industry and was applauded for her performance as the cunning wife and a nurse, in the Abdul Faththaah-directed critically acclaimed television series, Thiyey Mihithuge Vindhakee (2003) which was considered as one of the best series production in television industry. Abbas next starred as an obsessive and heartbroken lover of an established actor in Amjad Ibrahim's next directorial venture Sandhuravirey 2 (2004); a sequel to his 2002 horror film Sandhuravirey which presented Yoosuf Shafeeu and Mariyam Nisha in lead roles.
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His roles were repetitive and physically demanding; studios were not yet air-conditioned, and his tightly-scheduled job at Warners was anything but the indolent and "peachy" actor's life he hoped for. Although Bogart disliked the roles chosen for him, he worked steadily. "In the first 34 pictures" for Warner's, he told George Frazier, "I was shot in 12, electrocuted or hanged in 8, and was a jailbird in 9". Shipman indicates the quote is from a 1965 book about Bogart by Richard Gehman citing Frazier. This outline also appears in Frazier's June 2, 1944 profile of Bogart in Life magazine, p. 59 He averaged a film every two months between 1936 and 1940, sometimes working on two films at the same time.
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In retaliation to the rise of Filipino nationalism, the friars called the Indios (possibly referring to Insulares and mestizos as well) indolent and unfit for government and church positions. In response, the Insulares came out with Indios agraviados, a manifesto defending the Filipino against discriminatory remarks. The tension between the Insulares and Peninsulares erupted into the failed revolts of Novales and the Cavite Mutiny of 1872 which resulted to the deportation of prominent Filipino nationalists to the Marianas and Europe who would continue the fight for liberty through the Propaganda Movement. The Cavite Mutiny implicated the priests Mariano Gómez, José Burgos, and Jacinto Zamora (see Gomburza) whose executions would influence the subversive activities of the next generation of Filipino nationalists, José Rizal, who then dedicated his novel, El filibusterismo to these priests.
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Veronica Veronese (1872), another companion to A Sea–Spell Jerome McGann wrote that the painting is a "failure", caused by Rossetti's excessive intellectualizing of his work; previous critics suggested, to the contrary, that the work is flawed due to Rossetti's "slipshod" execution. Scholar Helene E. Roberts wrote that the painting is one of a group of depictions of Rossetti's "ideal woman". She wrote that the iconic image of womanhood dominated Rossetti's "dream world", and that the painting is intended to evoke similar reveries in the viewer, citing its musical theme as a prompt for "indolent musing". She argued that, although the combination of daydreaming and womanhood in A Sea–Spell could be pornographic, Rossetti encourages more spiritual responses, emphasizing the subject's face and making her exposed arms "masculine, or at best matronly".
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WM was first described by Jan G. Waldenström (1906–1996) in 1944 in two patients with bleeding from the nose and mouth, anemia, decreased levels of fibrinogen in the blood (hypofibrinogenemia), swollen lymph nodes, neoplastic plasma cells in bone marrow, and increased viscosity of the blood due to increased levels of a class of heavy proteins called macroglobulins. For a time, WM was considered to be related to multiple myeloma because of the presence of monoclonal gammopathy and infiltration of the bone marrow and other organs by plasmacytoid lymphocytes. The new World Health Organization (WHO) classification, however, places WM under the category of lymphoplasmacytic lymphomas, itself a subcategory of the indolent (low-grade) non-Hodgkin lymphomas. In recent years, there have been significant advances in the understanding and treatment of WM.
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Borland's last release during his lifetime was the album 5:00AM. A switch to Earth Records and a slight change of crew – Tim Smith of Cardiacs now co-produced with Borland – were the only ostensible differences between the new work and Cinematic. However, the money invested in the album allowed for much better production, a direct result of which was the recording and inclusion of "Baby Moon", a song which Borland had held onto since 1993 but did not want to waste 'on a lo-fi production'. The songs are generally punchier and more radio- friendly, such as opener "Stray Bullets", "City Speed" and "Redemption's Knees", but containing powerful, dark, indolent tracks which, at this point, Borland had made his solo trademark: "Vampiric" is arguably the best example of this in all of his discography.
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In recent studies, insight has been obtained on the genetic basis of this disease, supporting the hypothesis that MSK is due to a disruption at the 'ureteric bud-metanephric mesenchyme' interface. This explains why so many tubular defects coexist in this disease, and particularly a distal tubular acidification defect of which the highly prevalent metabolic bone disease is one very important consequence. In addition to the typical clinical phenotype of recurrent stone disease, other clinical profiles have now been recognized, that is, an indolent, almost asymptomatic MSK, and a rare form characterized by intractable, excruciating pain. It was previously believed that most cases of medullary sponge kidney were sporadic; however, recent studies show familial clustering of MSK is common and has an autosomal dominant inheritance, a reduced penetrance, and variable expressivity.
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"God Spede the Plough" (original: "God spede ƿe plouȝ: & sende us kǫꝛne Inolk") is the name of an early 16th-century manuscript poem which borrows twelve stanzas from Geoffrey Chaucer's Monk's Tale. It is a short, satirical complaint, listing the various indolent members of the clergy who will demand a share of the ploughman's harvest, rendering his work futile. The work contains a possible allusion to 1 Corinthians 9:10: "...when the plowman plows and the thresher threshes, they ought to do so in the hope of sharing the harvest." This verse is used by St Paul in an argument that the Apostles' ("we [who] have sown spiritual seed among you"1 Corinthians 9:11) food and other basic needs should be supplied by the laity of the early Christian church.
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Individuals with nodal or extranodal disease also present with: systemic B symptoms such as weight loss, night sweats, fevers, and/or fatigue in ~33% of cases; unexplained elevations in their blood levels of lactic acid dehydrogenase and beta-2 microglobulin in many cases; malignant cells infiltrating their bone marrow in 10-20% of cases; and/or localized Stage I or II disease in up to 50% of cases and disseminated Stage III or IV disease in the remaining cases. Bone marrow involvement may be due to DLBCL, NOS cells or low grade lymphoma cells; only DLBCL, NOS cell infiltrates indicate a worse prognosis. Uncommonly, DLBCL may arise as a transformation of marginal zone lymphoma (MZL) in individuals who have been diagnosed with this indolent cancer 4–5 years (median times) previously.
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According to Smith, the landlords should be in favour of policies which contribute to the growth in the wealth of nations, but they often are not in favour of these pro-growth policies because of their own indolent- induced ignorance and intellectual flabbiness. Critics and market abolitionists such as David McNally argue in the Marxist tradition that the logic of the market inherently produces inequitable outcomes and leads to unequal exchanges, arguing that Smith's moral intent and moral philosophy espousing equal exchange was undermined by the practice of the free market he championed. According to McNally, the development of the market economy involved coercion, exploitation and violence that Smith's moral philosophy could not countenance. The British economist John Maynard Keynes condemned laissez-faire economic policy on several occasions.
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Henriette Widerberg's soprano voice was not, as it was said, unusual because of its strength, but was described as having a soft timbre with an uncommon and personal sound, and her voice was once said to be superior to that of Jenny Lind. She was also a capable actress and could perform the speaking parts of her role well. She has been described as a natural talent, but also as an indolent character who neglected to educate herself because she did not have to: "She was not an educated singer; she was hardly able to read notes, and she rehearsed her parts without much discipline - but she was able to do this, because she could grasp things incredibly quickly."Ahnfelt, Arvid, Europas konstnärer, Norrköping 1887, M. W. Wallberg & Comp. Boktryckeri.
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However, Coplan implies that it may not have been met with such friendly ears from everyone, but urban Africans managed to look upon kwela as an authentic expression of their urban culture rather than an indolent pastime of juvenile delinquents. Kwela was even regarded as the new, close-harmony township style based on marabi or on the songs of migrant workers. Much like marabi, kwela became popular despite the adversities that it faced. Along with the music, young urban Africans also participated in dancing to kwela music, which entailed a sexually suggestive form of jive dancing where dancers shouted the word “kwela” periodically. The meaning of the word kwela is actually Zulu for “‘climb on’ or ‘get up,’” which is indicative for others to join the upbeat nature of the music.
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The New York Times listed "Pig Valentine" among its 1996 singles of the year. The band broke into the UK Top 40 with their fourth single "Talk to Me" (Indolent, 1996), the video for which extensively featured the Newport Transporter Bridge. This was followed by their debut album, The Big 3, which was produced by Al Clay, Reviews called it "as close to soar-away rock perfection as it's possible to imagine" by the NMENME, 30 November 1996 and "pure, unadulterated, no nonsense, emotional, tuneful, impassioned, purposeful, hedonistic rock 'n' roll"Melody Maker, December 1996 by Melody Maker. The album was included in Select magazine's top 30 albums of 1996 and Mojo's 2003 retrospective feature "Top 12 Britpop albums of the 90s", which called it "a devilishly evocative document of the period".
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His professional income rose to about £12,000 a year; but he was constantly in pecuniary difficulties, for he was shiftless, indolent, and without method, open-handed and even prodigal in his benefactions – and prodigal, too, in less reputable directions, for he became a reckless gambler, and habits of intemperance grew upon him. He did however have a notable student, John Thomas Smith who trained with him for three years. Sherwin died in extreme penury on 24 September 1790according to George Steevens, the editor of Shakespeare, at The Hog in the Pound, an obscure alehouse in Swallow Street, or, as stated by his pupil J.T. Smith, in the house of Robert Wilkinson, a printseller in Cornhill. It is as an engraver that Sherwin is most esteemed; and it may be noted that he was ambidextrous, working indifferently with either hand upon his plates.
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A healthy boxer puppy. Leading health issues to which Boxers are prone include cancers, heart conditions such as aortic stenosis and arrhythmogenic right ventricular cardiomyopathy (the so- called "Boxer cardiomyopathy"), hypothyroidism, hip dysplasia, and degenerative myelopathy and epilepsy; other conditions that may be seen are gastric dilatation volvulus (also known as bloat), intestinal problems, and allergies (although these may be more related to diet than breed). Entropion, a malformation of the eyelid requiring surgical correction, is occasionally seen, and some lines have a tendency toward spondylosis deformans, a fusing of the spine, or dystocia.A survey of dystocia in the Boxer breed Other conditions that are less common but occur more often in Boxers than other breeds are hystiocytic ulcerative colitis (sometimes called Boxer colitis), an invasive E. coli infection, and indolent corneal ulcers, often called Boxer eye ulcers.
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Results showed 54% of participants with relapsed FL and 58% of participants with SLL experienced ORR. The U.S. label for idelalisib has a boxed warning describing toxicities that can be serious and fatal, including liver toxicity, severe diarrhea, colon inflammation, lung tissue inflammation (pneumonitis) and intestinal perforation, and the manufacturer was required to put in place a Risk Evaluation and Mitigation Strategy (REMS) under which the risk of toxicities would be managed. In March 2016, as reports were made from three ongoing clinical trials of serious adverse events and deaths, mostly due to infections, the European Medicines Agency opened a review of the drug and its risks. On March 21, 2016 Gilead Sciences (the manufacturer of idelalisib) alerted healthcare providers about decreased overall survival and increased risk of serious infections in patients with CLL and indolent non-Hodgkin lymphoma (iNHL) treated with idelalisib.
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Dease was described in George Simpson's Character Book (compiled in 1832), as being: > About 45 years of Age. Very steady in business, an excellent Indian trader, > speaks several of the Languages well and is a man of very correct conduct > and character. Strong, vigorous and capable of going through a great deal of > Severe Service but rather indolent, wanting in ambition to distinguish > himself in any measure out of the usual course, inactive until aroused to > exertion and over easy and indulgent to his people which frequently > occasions laxity of discipline, but when his temper gets ruffled he becomes > furiously violent. His judgement is sound, his manners are more pleasing and > easy than those of many of his colleagues, and altho' not calculated to make > a shining figure, may be considered a very respectable member of the > concern.
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Immigration from Mexico was not formally regulated until the Immigration Act of 1917, but enforcement was lax and many exceptions were given for employers. In 1924, with the establishment of the U.S. Border Patrol, enforcement became more strict, and in the late 1920s before the market crash, as part of a general anti-immigrant sentiment, enforcement was again tightened. Due to the lax immigration enforcement, and porousness of the border, many citizens, legal residents, and immigrants did not have the official documentation proving their citizenship, had lost their documents, or just never applied for citizenship. Prejudice played a factor: Mexicans were stereotyped as "unclean, improvident, indolent, and innately dull", so many Mexicans did not apply for citizenship because they "knew that if [they] became a citizen [they] would still be, in the eyes of the Anglos, a Mexican".
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Initial recording sessions for third album, Be a Girl, proved unsuccessful—first choice producer Dagge Lunquist took paternity leave late in 1993 and a second attempt with producer Micke Herrström had to be abandoned after just a week and a half when, first engineer Adam Kviman, then Herrström were taken sick with hearing injuries. "Love in June", the only song to be completed with Micke Herrström, was released as a single while the band tried again to record Be a Girl, this time with producer Nille Perned. The album was finally finished by late 1994 and was released along with second single, "You and Me Song", to critical acclaim in their native country. Shortly afterwards the band came to the attention of Indolent Records in the United Kingdom who signed The Wannadies in the summer of 1995.
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Besides, she possessed a sharp intellect, which made her into a faithful advisor of my father's." The characteristics of Circassian and Northwest Georgian women were further articulated in 1839 by the author Emma Reeve who, as stated by Joan DelPlato, differentiated "between 'the blond Circassians' who are 'indolent and graceful, their voices low and sweet' and what she calls the slightly darker- skinned Georgians who are 'more animated' and have more 'intelligence and vivacity than their delicate rivals. Similar descriptions of the Circassian women appear in Florence Nightingale's travel journal where Nightingale called Circassians "the most graceful and the most sensual-looking creatures I ever saw". According to the feminist Harriet Martineau, Circassians were the only saving virtue of the Egyptian harem where these Circassian mothers produced the finest children and if they were to be excluded from the harem, the upper class in Egypt would be doomed.
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Hattie McDaniel, the first African-American Oscar winner Black commentators criticized the film for its depiction of black people and as a glorification of slavery; they have done so since the release of the film, but initially newspapers controlled by white Americans did not report on these criticisms. Carlton Moss, a black dramatist, observed in an open letter that whereas The Birth of a Nation was a "frontal attack on American history and the Negro people", Gone with the Wind was a "rear attack on the same". He went on to characterize it as a "nostalgic plea for sympathy for a still living cause of Southern reaction". Moss further called out the stereotypical black characterizations, such as the "shiftless and dull-witted Pork", the "indolent and thoroughly irresponsible Prissy", Big Sam's "radiant acceptance of slavery", and Mammy with her "constant haranguing and doting on every wish of Scarlett".
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Mr. Bennet is described by the narrator in his first appearance in the book as "so odd a mixture of quick parts, sarcastic humour, reserve, and caprice, that the experience of three and twenty years had been insufficient to make his wife understand his character", and it is this same ironic, cynical, dry, wry sense of wit and humour that irritates his wife (both because she cannot understand it, and because he does not comply with her every wish and whim). The authorial Narrator points out Mr. Bennet's many acts of negligence regarding his duties as husband and father. If he draws the sympathy of the reader by his skill at irony, he has nevertheless a certain number of faults: indifferent and irresponsible, self-centred, stubborn, indolent, and a dislike of company. According to author Phyllis Ferguson Bottomer, Mr. Bennet may suffer from a form of autism.
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The diagnoses of NKCE and LG depends on clinical and pathological findings indicating that the two diseases: a) are indolent and non-malignant; b) usually manifested by mild, vague, or no symptoms; c) localize to the GI tract without involvement of the head, neck, or organs such as the liver and spleen; d) consist of one or more lesions localized primarily to the lamina propria of the esophagus, stomach, small intestine, and/or large intestine (for NKCE} or to the stomach (for LG); and e) involve lesions which contain medium-to large- sized, atypical, and non-clonal lymphocytes that are activated NK cells (see Pathophysiology section) which proliferate at moderately rapid rates (as gauged by, e.g. analysis of their Ki-67 protein levels), lack evidence of Epstein-Barr virus infection, gene mutations, or chromosome abnormalities, and show little evidence of centering around, and destroying, blood vessels.
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The action unfolded in fairy-land, peopled with good and bad spirits who both advanced and impeded the plot, which was interlarded with comically violent (and often scabrous) mayhem. As in the Bakken pantomimes, that plot hinged upon Cassander's pursuit of Harlequin and Columbine—but it was complicated, in Baptiste's interpretation, by a clever and ambiguous Pierrot. Baptiste's Pierrot was both a fool and no fool; he was Cassandre's valet but no one's servant. He was an embodiment of comic contrasts, showing > imperturbable sang-froid [again the words are Gautier's], artful foolishness > and foolish finesse, brazen and naïve gluttony, blustering cowardice, > skeptical credulity, scornful servility, preoccupied insouciance, indolent > activity, and all those surprising contrasts that must be expressed by a > wink of the eye, by a puckering of the mouth, by a knitting of the brow, by > a fleeting gesture.In La Presse, August 31, 1846; tr.
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Macon Shibut, Paul Morphy and the Evolution of Chess Theory, Dover Publications, 2004, p. 121. . Howard Staunton in The Chess-Player's Handbook (1847) advised inexperienced players to accept odds offered by superior players and, upon improving to the point that they can themselves give odds to some players, to avoid playing such players on even terms, warning that doing so is apt to induce "an indolent, neglectful habit of play". In 1849, Staunton published The Chess-Player's Companion, a 510-page work "chiefly directed to the exposition of openings where one party gives odds".Howard Staunton, The Chess- Player's Companion, Henry G. Bohn, 1849, p. v. Just over 300 pages were devoted to odds games: Book I (pages 1 to 185) contained games played at various odds, and most of Book V (pages 380–496) discussed various types of odds, including exotic and unusual ones.
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For Calvin, violations of this commandment are not confined to money, or merchandise, or lands, but extend to every kind of right. We defraud our neighbors to their hurt if we decline any of the duties which we are bound to perform towards them. God's wrath is incurred if an agent or an indolent steward wastes the substance of his employer, or does not give due heed to the management of his property; if he unjustly squanders or luxuriously wastes the means entrusted to him; if a servant holds his master in derision, divulges his secrets, or in any way is treacherous to his life or his goods. Likewise, a master incurs God's wrath if he cruelly torments his household, because he is guilty of theft before God; along will all who fail to deliver what he owes to others, keeps back, or makes away with what does not belong to him.
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Under the indolent and thoroughly worldly Frederick III (1522–32), brother of the Archbishop of Cologne, Hermann of Wied, Lutheranism spread rapidly after 1524, especially in the city. Scarcely any opposition to the innovation was made by the next bishop, Franz von Waldeck (1532–53), who from the first planned to aid the Reformation in his three prince-bishoprics of Münster, Minden, and Osnabrück, in order to form out of these three a secular principality for himself. He was obliged, indeed, for the sake of his endangered authority, to proceed against the Anabaptists in the city of Münster; but he did little for the restoration of the Faith, and at last joined the Smalkaldic League. William of Ketteler (1553–57) was more Protestant than Catholic: although he regarded himself as an administrator of the old Church, and took the Tridentine oath, he refused to comply with the demands of Rome, and resigned in 1557.
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He graduated Bozeman High School in May 2001 and soon won a scholarship to attend the American Academy of Dramatic Arts in Los Angeles. During his first semester at AADA, Noah was offered a part in a Chris Eyre film titled Skinwalkers as a teenage gang- leader and suspected murderer—a role far different from the shy, devoted son he played in Skins. In the Southwest Repertory Company's production of the play "The Indolent Boys", written by N. Scott Momaday, Noah played the role of a young Native man in a boarding school in the 1800s, who was being trained to be a Christian missionary, but is conflicted between his Native culture and the Christian religion inculcated. In the spring of 2005, Noah was cast in Native Voices at the Autry's Native American adaptation of William Shakespeare's Romeo and Juliet entitled Kino and Teresa, written by James Lujan (Taos Pueblo), where he played the villain Eladio (an adaption of Tybalt).
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On Tyneside, the leading coal-owners protected their profits by a price-setting cartel (the 'Grand Alliance'); Lowther instead adopted other strategies to maintain his dominance. Sir John Clerk of Penicuik described him in 1739 as "an indolent old man, and knows nothing about coal works but in order to grow rich carried them on by the best advice and seems indeed to be very well served" but the context of the remark is that Clerk was planning (and gathering material for) a learned dissertation on coal-mining Lowther's principal residence was in London, and the success of his efforts did depend largely on his choice of able subordinates, most notably the Spedding brothers (John and Carlisle), but he kept up an extensive and detailed correspondence with them and travelled to Whitehaven (where Clerk of Penicuik met him in August 1739) most summers. Under Lowther, the pits at Whitehaven more than trebled their annual output of coal; their profits increased more than sixfold.
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On Earth, audiences are entranced by the musical entertainments staged by an alien troupe, the Ninth Company of the planet Rlaru. Dame Isabel Grayce (one of a long line of formidable society matrons in Vance's works) has sponsored the entertainments; when the Ninth Company disappears without a trace, she proposes to recoup her losses and bring culture to the wastes of space by forming an opera company which Adolph Gondar (the discoverer of Rlaru) will pilot on a tour of suitable planets, with Rlaru as ultimate destination. Singers, orchestra, a British conductor (Sir Henry Rixon) are engaged; an argumentative critic, Bernard Bickel, who thinks the Ninth Company were fakes, is hired as musical consultant. Dame Isabel's indolent and aptly named nephew Roger Wool (one of a long line of Vancian put-upon nephews) tags along also, smuggling his new girlfriend Madoc Roswyn, who claims to be a simple girl from Merioneth in Wales, aboard the ship as a stowaway.
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Hydroxyurea(Hydroxycarbamide) Lymphocyte-variant hypereosinophilia usually takes a benign and indolent course. Long-term treatment with corticosteroids lowers blood eosinophil levels as well as suppresses and prevents complications of the disease in >80% of cases. However, signs and symptoms of the disease recur in virtually all cases if corticosteroid dosages are tapered in order to reduce the many adverse side effects of corticosteroids. Alternate treatments used to treat corticosteroid resistant disease or for use as corticosteroid-sparing substitutes include interferon-α or its analog, Peginterferon alfa-2a, Mepolizumab (an antibody directed against IL-5), Ciclosporin (an Immunosuppressive drug), imatinib (an inhibitor of tyrosine kinases; numerous tyrosine kinase cell signaling proteins are responsible for the growth and proliferation of eosinophils {see clonal eosinophilia}), methotrexate and Hydroxycarbamide (both are chemotherapy and immunosuppressant drugs), and Alemtuzumab (an antibody that binds to the CD52 antigen on mature lymphocytes thereby marking them for destruction by the body).
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In 1702, after the first unsuccessful campaign of Catinat and Villeroi, he was placed in command of the Franco-Spanish army in Italy. During three campaigns in that country, he proved himself a worthy antagonist to Prince Eugène of Savoy, whom he at last defeated in 1705 at Cassano in a magnificent show of courage and command over his troops, converting the impending defeat that his indolent brother Philippe had incurred, into a glorious success. The next year, after holding his own as before, and gaining another victory at Calcinato, he was sent to Flanders to repair the disaster of Ramillies. Following the departure of Vendôme to shore up the shattered army in the Flanders, Prince Eugène and the Duke of Savoy inflicted a heavy loss on the French under the duc d'Orléans and Ferdinand de Marsin at the Battle of Turin, driving the French out of Italy by the end of the year.
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Penciling in a contract with Wuhan Guanggu partway through 2006,阿根廷尖刀拒绝接受试训 汉军无奈冒险签新前锋 新浪体育 Demus did well in training and debuted as they took on Tianjin Teda,光谷新外援磨刀霍霍 德莫斯处子秀欲拿泰达开张 北方网 but did not fit in well with Zheng Bin upfront,汉军“新枪”德莫斯受困 裴恩才为其找理由 搜狐体育 putting in what was seen as an indolent performance with no goals in his first five appearances.五轮联赛一球未进 天价外援成质疑焦点 搜狐体育 In total, he made 17 appearances and 5 goals in the Chinese Super League.
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As such, when he is urgently called back to New York by his sister, Miriam, who is desperate to see her children one last time before she dies, not only is Tono able to go by aeroplane, a mode of travel that would have been previously inconceivable for him, but when he arrives he easily facilitates this final meeting, and is able to offer comfort and council to his sister, his nephews, and their indolent father, Charlie. Bebb’s journey to Texas has yielded fruit in the form of a wealthy new benefactor, Herman Redpath, a native American businessman who is convinced that Bebb’s prayers for him have brought a guarantee of good health and continued prosperity. Thus, Tono’s final conclusions are no less confused and uncertain than his expectations at the outset of the novel: perhaps Bebb is the real deal, perhaps he is not. The couple are married at Bebb’s new home on the Redpath ranch, where the industrious preacher is engaged in building a new Church of Holy Love, and extending his ministry across the USA.
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Retrieved on 2012-04-01. But they were dogged by alcohol problems, and after an exhaustive three tours of the USA in 1997, never toured again.Select, May 1997 They released their second album Joya Magica, in 1998 but the band were dropped from their label deal along with other acts at Indolent and split soon after.Q, July 1998 The band recorded two sessions for John Peel's BBC Radio 1 show, in 1996 and 1998, and appear in the top 125 Peel sessions of all time.Radio 1 - Keeping It Peel - Sessions - Best 125. BBC. Retrieved on 2012-04-01. Mike Cole once played guitar for Newport's The Darling Buds but was asked to leave after just three gigs. He was also asked to stand in for Paul McGuigan on Oasis' 1996 tour of the USA, but declined.The Chart Show, 20 January 1996 The track "Hair", written by Mike Cole about his then-girlfriend Donna Matthews, was placed Number 7 in Mojo's "100 Most Miserable Indie Songs of All Time" feature.
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Marble table support adorned by a group including Dionysos, Pan and a Satyr; Dionysos holds a rhyton (drinking vessel) in the shape of a panther; traces of red and yellow colour are preserved on the hair of the figures and the branches; from an Asia Minor workshop, 170–180 AD, National Archaeological Museum, Athens, Greece The god, and still more often his followers, were commonly depicted in the painted pottery of Ancient Greece, much of which made to hold wine. But, apart from some reliefs of maenads, Dionysian subjects rarely appeared in large sculpture before the Hellenistic period, when they became common.Smith 1991, 127–129 In these, the treatment of the god himself ranged from severe archaising or Neo Attic types such as the Dionysus Sardanapalus to types showing him as an indolent and androgynous young man, often nude.as in the Dionysus and Eros, Naples Archeological Museum Hermes and the Infant Dionysus is probably a Greek original in marble, and the Ludovisi Dionysus group is probably a Roman original of the second century AD. Well-known Hellenistic sculptures of Dionysian subjects, surviving in Roman copies, include the Barberini Faun, the Belvedere Torso, the Resting Satyr.
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Some Buried Caesar first appeared in abridged form in The American Magazine (December 1938), with watercolor illustrations by Ronald McLeod (18971977) While on their way to a rural exposition in upstate New York to show orchids, Nero Wolfe and Archie Goodwin are involved in a minor car accident. On their way to a nearby house to phone for help, they are threatened by a large bull but are eventually rescued by Caroline Pratt, a local golf champion, and her acquaintance Lily Rowan. The house and bull belong to Thomas Pratt, Caroline's uncle and the owner of a large chain of successful fast food restaurants, and he has purchased the bull—a champion Guernsey called Hickory Caesar Grindon—in order to barbecue it as part of a publicity stunt. While Wolfe and Archie enjoy Pratt's hospitality, they meet several of Pratt's family and neighbours—Jimmy Pratt, Pratt's indolent nephew; Monte McMillan, the original owner of Caesar, who sold the bull to Pratt after falling into financial difficulties; Clyde Osgood and his sister Nancy, the children of Pratt's neighbour Frederick Osgood; and a New Yorker named Howard Bronson, who is apparently a friend of Clyde.
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