But the sores that worried the vets were actually tumors that were ulcerating and rotting away under assault by T-cells.
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Ever since Columbine, almost 20 years ago, I've absorbed the news of more mass shootings than I can count with an ulcerating rage that gradually scabbed over into deadened cynicism.
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" His subsequent elegy for Lincoln is a genuinely lovely piece of writing: "Difficulties, instead of irritating him as they do most men, only increased his reliance on patience; opposition, instead of ulcerating, only made him more tolerant and determined.
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Sulfonated phenolics/sulfuric acid (brand name Debacterol) liquid topical agent that is used in the treatment of ulcerating oral mucosal lesions and minor oral abrasions.
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Granuloma inguinale is a bacterial disease caused by Klebsiella granulomatis (formerly known as Calymmatobacterium granulomatis) characterized by genital ulcers. It is endemic in many less-developed regions. It is also known as donovanosis, granuloma genitoinguinale, granuloma inguinale tropicum, granuloma venereum, granuloma venereum genitoinguinale, lupoid form of groin ulceration, serpiginous ulceration of the groin, ulcerating granuloma of the pudendum, and ulcerating sclerosing granuloma. Oral manifestations are also notably seen .
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Secondary bleeding This type of bleeding usually begins 7 to 10 days post extraction, and is most likely due to infection destroying the blood clot or ulcerating local vessels.
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Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, chronically inflamed, or scarred skin.Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. .
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Tolazoline (Priscoline) has been shown to offer symptomatic relief from sympathetic overactivity.Antibiotics are necessary when massive hyperhidrosis, which may rapidly lead to miliaria rubra, is present. This can easily progress to bacterial secondary infection with a tendency for ulcerating pyoderma.
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The price he pays is an injury to his knee, which progresses to ulcerating inflammation of the joint (in a time before the invention of antibiotics, at a place without any opportunity to do a sterile amputation), and he dies slowly in pain.
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Chronic inflammation can cause the cyst to take the form of a granuloma. This granuloma mimics a squamous-cell carcinoma (both clinically and histologically) and these ulcerating solitary cysts are called Cock's peculiar tumour. Chronic inflammation causes the cyst to take the form of a granuloma. This granuloma mimics a squamous cell tumour.
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The classical period began when the disease was first recognized in the Middle Ages. The term lupus is attributed to 12th-century Italian physician Rogerius Frugard, who used it to describe ulcerating sores on the legs of people. No formal treatment for the disease existed and the resources available to physicians to help people were limited.
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It is thought that the reduce efficacy of immune surveillance associated with these predisposing conditions or treatments maintain EBV in a dormant state systemically but not where EBV+ B cells are prevalent, i.e. in afflicted mucous membranes and skin. Consequently, the EBV+ cells at these sites proliferate and destroy tissue to create ulcerating lesions. Persons developing these ulcers are usually elderly.
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Signs of glanders include the formation of nodular lesions in the lungs and ulceration of the mucous membranes in the upper respiratory tract. The acute form results in coughing, fever, and the release of an infectious nasal discharge, followed by septicaemia and death within days. In the chronic form, nasal and subcutaneous nodules develop, eventually ulcerating; death can occur within months, while survivors act as carriers.
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In 1881 a Scottish professor of surgery, Kenneth MacLeod described lesions of dermal ulcer in Madras as "serpiginous ulcer". In 1896 J.H. Conyers and C.W. Daniels reported the same disease as "lupoid form of the so-called groin ulceration" in New Guinea. In 1897 similar symptom was described by J. Galloway as "ulcerating granuloma of the pudendum" from one infected person in London. This became a commonly used medical term.
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Erythema nodosum is a form of panniculitis characterised by tender red nodules, 1–10 cm, associated with systemic symptoms including fever, malaise, and joint pain. Nodules may become bluish- purple, yellowing, and green, and subside over a period of 2–6 weeks without ulcerating or scarring. Erythema nodosum is associated with infections, including Hepatitis C, EBV and tuberculosis, Crohn's disease and sarcoidosis, pregnancy, medications including sulfonamides, and some cancers, including Non-Hodgkin lymphoma and pancreatic cancer.
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A light infection within a horse with likely not exhibit any symptoms of infection. However, a horse with a heavy infection can experience GI issues, weakness and anemia. Immunocompromised horses (ex: extremely old and extremely young) can have only a light parasite load, but experience infection symptoms associated with extreme pathology. The tapeworm perforating through the intestinal wall and ulcerating the mucosal layer of the stomach at the site of attachment has also been seen with this parasite leading to the intussusception.
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Plasmablastic lymphoma lesions are most commonly rapidly growing, soft tissue masses that may be ulcerating, bleeding, and/or painful. In a recent (2020) review of published cases, individuals presenting with PBD were typically middle-aged or elderly (range 1–88 years; median age 58 tears) males (~73% of cases). Only a few cases have been reported in pediatric cases. The PDL lesions occurred most commonly in lymph nodes (~23% of cases), the gastrointestinal tract (~18%), bone marrow (16%), and oral cavity (12%).
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A mutation in the cytosolic phospholipase A2-α gene (PLA2G4A) has been identified as the cause of this disease in one family.Brooke MA, Longhurst HJ, Plagnol V, Kirkby NS, Mitchell JA, Rüschendorf F, Warner TD, Kelsell DP, Macdonald TT (2012) Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α. Gut In this family the mutation was inherited as an autosomal recessive. It is not yet known if this gene is the cause of this disease in other families.
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Involvement of lymph nodes is uncommon and generally due to the tumors' spread from their primary sites. About 70% of ENLTL cases are diagnosed as having cancer stage I or II disease (tumors localized to a single site or region of the body ) with the remainder having disseminated stage III or IV disease. All stages of ENKTL involve destructive, ulcerating, and necrotic lesions. Histologically, these tumors are composed of small, medium-sized, or large malignant lymphoid cells often accompanied by a mixture of benign inflammatory cells.
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Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain. The use of pushpanjan, probably zinc oxide, as a salve for eyes and open wounds, is mentioned in the Indian medical text the Charaka Samhita, thought to date from 500 BC or before. Zinc oxide ointment is also mentioned by the Greek physician Dioscorides (1st century AD). Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine.
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Prior to Stevens's trip to the hospital, "A local physician suspected Albert had a malignant ulcer that had spread to the liver and advised him to consult specialists at the University of California Hospital." Stevens's surgeons found a "huge, ulcerating, carcinomatous mass that had grown into his spleen and liver... Half of the left lobe of the liver, the entire spleen, most of the ninth rib, lymph nodes, part of the pancreas, and a portion of the omentum... were taken out" to help prevent the spread of the cancer that Stevens did not have.
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Erythema nodosum is due to inflammation of the underlying subcutaneous tissue, and is characterized by septal panniculitis. Pyoderma gangrenosum is a less common skin problem, occurring in under 2%, and is typically a painful ulcerating nodule. Crohn's disease also increases the risk of blood clots; painful swelling of the lower legs can be a sign of deep venous thrombosis, while difficulty breathing may be a result of pulmonary embolism. Autoimmune hemolytic anemia, a condition in which the immune system attacks the red blood cells, is also more common in Crohn's disease and may cause fatigue, a pale appearance, and other symptoms common in anemia.
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Extranodal NK/T cell lymphoma, nasal type (ENKTL), is a malignancy of NK or, less commonly, T cells that afflicts primarily Asians and the indigenous populations of Mexico, Central America, and South America. It is less common in Western countries of the northern hemisphere. The disease usually consists of malignant tumors in the nasal cavities, paranasal sinuses, palate, tonsils, nasopharynx, hypopharynx, and/or larynx or, in ~20% of cases, tumors in the skin, soft tissues, gastrointestinal tract, testes, and/or central nervous system. Afflicted individuals are usually middle aged and present with obvious tumors, hemoptysis, ulcerating skin nodules, obstructions in the upper airways, and/or obstructions/bleeding in the lower gastrointestinal tract, particularly the colon.
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