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278 Sentences With "subdomain"

How to use subdomain in a sentence? Find typical usage patterns (collocations)/phrases/context for "subdomain" and check conjugation/comparative form for "subdomain". Mastering all the usages of "subdomain" from sentence examples published by news publications.

For instance, according to the page banner, the subdomain Berkeley.predpol.
There is no Predpol subdomain for the city of Oakland.
The company did not say when it began hosting the subdomain.
It's also allowing admins to specify certain teams with subdomain verification.
One former official said it was better understood as a subdomain of TNet.
These numbers can then be entered into the Terminal subdomain on the website to produce a unique character.
When this hash is entered as a subdomain on the website, it produces a short string of numbers: '361556198981918.
In any case, the number makes a reappearance on the knowgodsjustwork site as the subdomain hosting the morse code.
Greenberg also noted that the trending videos subdomain specifically saw a massive spike in referral traffic from these sites.
Nearly all of the sites also have an active video subdomain just like Myspace and others in the scheme.
Years ago, many sites had different versions of their websites for phones — often at a different subdomain like mobile.theverge.com.
The company also provides its corporate customers with a unique subdomain, so anyone in the company can send a Cheerbox.
By linking certain accounts or users to a subdomain, admins can better control who can access an enterprise's Dropbox account.
In the encrypted chat, the hacker also provided evidence of other breached websites, including a subdomain belonging to manufacturing giant Foxconn.
By doing this, Nk not only takes control of the subdomain, but also receives any and all data sent to it.
Motherboard verified the BoingBoing report with its own subdomain scanning technique, which verified that the login portals mentioned in the BoingBoing report exist.
While working as a security researcher with cybersecurity site SafetyDetective, Nk discovered that he was able to take over the Microsoft subdomain, http://success.office.
When this image is inverted, it once again produces a code that takes the visitor to another subdomain where there are a string of numbers.
He used a CNAME record, a canonical record used to link one domain to another, to point the unconfigured subdomain to his own Azure instance.
In doing so, he controlled the subdomain — and any data sent to it, he said in a write-up shared with TechCrunch prior to publication.
In May, a security researcher found a security weakness in a T-Mobile subdomain used by staff, which returned customer data without requiring a password.
And Google has thrown in its own extra hint with the #MadeByGoogle hashtag — to say nothing of an entire website on with the "madeby" subdomain.
And in the case of the first one in the list who on earth it was… Turns out cloudfront is an Amazon Web Services Content Delivery Network subdomain.
In particular, Pitt said, the GCI defines an interesting relationship between vectors on the surfaces of overlapping convex shapes, which could blossom into a new subdomain of convex geometry.
Krieger of Myspace told BuzzFeed News the trending videos subdomain was set up and hosted by a company called ScreenRush in order to test driving paid traffic to the site.
The company said it first learned of its business relationship with Gab on Tuesday, following a report by journalist Judd Legum that found Amazon Web Services was hosting the Gab subdomain.
According to TechCrunch, security researcher Mossab Hussein of Dubai-based SpiderSilk found that a database on a MoviePass subdomain containing some 161 million records was left exposed to the wider internet.
A testing subdomain on HTC's website, spotted by Roland Quandt, has confirmed the already-leaked specs and design of HTC's next flagship phone, while also giving us an indication of its price.
As such, anyone with an internet connection could have accessed the Republican data operation used to power Donald Trump's presidential victory, simply by navigating to a six-character Amazon subdomain: "dra-dw".
Worst of all, the malicious URL looks legitimate — because the user still logs in through Microsoft's systems, and the "wreply" parameter in the URL also doesn't look suspect because it's an Office subdomain.
Almost exactly a year ago, the software and services giant fixed a similar vulnerability in which researchers were allowed to alter the records of an improperly configured Microsoft subdomain and steal Office account tokens.
According to the researcher, who goes by the name MLT, the worst vulnerability was in a subdomain of the website of the Defense Contract Management Agency, a military agency responsible for contract administration services.
A subdomain of the internet of things, IoD encompasses the bevy of connected sex toys adding a little digital spice to our love lives — just maybe not the kind of spice anyone had in mind.
Some sites, like one Justice Department subdomain, are at the time of writing completely inaccessible because the domain is included in Chrome's HSTS preload list, used by browsers to force browsers into using HTTPS only when accessing pages on the domain.
Once the target clicked on the link, the hackers could force the service that provided the login—be it Facebook or Xbox Live—to resend the login token to an old and vulnerable Epic Games subdomain dedicated to Unreal Tournament statistics.
The site was easily found on a subdomain of the state government's website, and it was indexed by Google, which cached copies of not only the site itself, but also its attendance record pages that still contain Aadhaar numbers in each worker's photo.
In his post, Mill suggests the best way to measure the impact of the government's work on HTTPS is to look at web traffic — if most visitors to government websites enjoy a secure connection, then an abandoned subdomain shouldn't make much difference.
That promise garnered it a bunch of attention from privacy experts who dug around and found a first-party tracker embedded on its site which uses a subdomain (that's mostly random) in order to redirect to a third party — thereby making it difficult to block (i.e.
This video shows what the experience looked like on the Myspace subdomain: Social Puncher recorded ads being shown during fraudulent sessions for major brands such as Coca-Cola, Fios (Verizon), State Farm, Hershey's, the Home Depot, Chase, and at least 14 brands belonging to Procter & Gamble, such as Tide and Always.
While Let's Encrypt has the clear(ly worthy) goal of helping lock down more Internet connections, the free system has itself not been immune to abuse — as noted by security firm Trend Micro, which earlier this year found malvertisers had used a 'domain shadowing' technique to insert a redirect to a site hosting a banking trojan by creating a subdomain under a domain certified using Let's Encrypt.
Motherboard was able to verify the following subdomains associated with seventeen US cities: When visited by Motherboard, many of the login portals contain a banner in the upper-left hand corner that identifies the city or region that corresponds to the subdomain (for example, the Hollywood login mentions the Los Angeles Police Department.) This banner feature is not something that's automatically generated, adding weight to the idea these are deliberately created login portals.
Its online portal, which was originally a subdomain of Tribunnews.com, is currently become subdomain of Bolasport.com.
The Super Ball online portal, which was originally a subdomain of Tribunnews.com, is currently become subdomain of Bola portal.
According to RFC 1034, "a domain is a subdomain of another domain if it is contained within that domain". Based on that definition, a host cannot be a subdomain, only a domain can be a subdomain.
At the same time as the subdomain correction, the coarse correction is computed, which consists of the displacement at all subdomain corners, interpolated between the corners on each subdomain separately by the condition that the subdomain assumes the same shape as it would with no forces applied to it at all. Then the interface forces, same as for the subdomain correction, are applied to find the values of the coarse correction at subdomain corners. Thus, the interface forces are averaged and the coarse solution is found by the Galerkin method. Again, the values of the coarse correction on subdomain interfaces is, in general, discontinuous across the interface.
So, suppose we have an elastic structure divided into nonoverlapping substructures, and, for simplicity, suppose the coarse degrees of freedom are only subdomain corners. Suppose forces applied to the structure are given. The first step in the BDDC method is the interior correction, which consists of finding the deformation of each subdomain separately given the forces applied to the subdomain except at the interface of the subdomain with its neighbors. Since the interior of each subdomain moves independently and the interface remains at zero deformation, this causes kinks at the interface.
Mizusawa Domain was one such short-lived subdomain. The Ichinoseki Domain, ruled by the Tamura family, was another subdomain, and survived to the end of the Edo period.
A subdomain will also have a separate zone file with a SOA record (Start of Authority). Any Fully Qualified Domain Name can be a host or a subdomain.
The forces on the interface necessary to keep the kinks in balance are added to the forces already given on the interface. The interface forces are then distributed to the subdomain (either equally, or with weights in proportion to the stiffness of the material of the subdomains, so that stiffer subdomains get more force). The second step, called subdomain correction, is finding the deformation for these interface forces on each subdomain separately subject to the condition of zero displacements on the subdomain corners. Note that the values of the subdomain correction across the interface in general differ.
A Japanese news publishing company called Asahi Interactive owns the ZDNet Japan website. According to alexa.com statistics, the Japan.zdnet.com subdomain is the second most visited on ZDNet, after the blogs subdomain.
A vanity domain is a subdomain of an ISP's domain that is aliased to an individual user account, or a subdomain that expresses the individuality of the person on whose behalf it is registered.
The hierarchy of domains descends from right to left; each label to the left specifies a subdivision, or subdomain of the domain to the right. For example, the label example specifies a subdomain of the com domain, and www is a subdomain of example.com. This tree of subdivisions may have up to 127 levels. A label may contain zero to 63 characters.
The structure of E. Coli's helicase binding domain. Rendered from PDB 2R6A. The lower two helices form the helical hairpin of the C2 subdomain. The remaining five helices form the helical bundle of the C1 subdomain.
The regulatory domain is further subdivided into a N-terminal and C-terminal subdomain. Small molecule effector binding occurs in the cleft between these subdomains. Binding to phosphorylated Hpr/Crh occurs along the regulatory domain's N-subdomain.
The south-central Eyre Peninsula straddles the boundary between the Archaean to early Palaeoproterozoic Coulta Subdomain and the Cleve Subdomain, a Palaeoproterozoic orogenic belt ("mobile zone") probably representing a shelf or basinal depository for the Hutchison Group (ca. 1900–1845 Ma) prior to its deformation during the Kimban Orogeny (ca. 1845–1710 Ma). On northeastern Eyre Peninsula, the Cleve Subdomain is bounded by the slightly younger Moonta Subdomain which is characterised by less intensely deformed metamorphosed acid volcanics and sediments ranging from the Myola Volcanics and Moonta Porphyry to the Moonabie Formation and Wandearah Metasiltstone.
The last subdomain of the RNase E catalytic site is DNase I, which is named for its conformational similarity to an endonuclease structure that cleaves double-stranded DNA. In ribonuclease E, DNase I subdomain self-complements to dominate the dimer interface.
In the Domain Name System (DNS) hierarchy, a subdomain is a domain that is a part of another (main) domain. For example, if a domain offered an online store as part of their website `example.com`, you might use the subdomain `shop.example.com` .
Mutations within the CBS subdomain or a complete deletion of the domains do not impair the in vitro catalytic activity of IMPDH. An in vivo deletion of the CBS subdomain in E. coli suggests that the domain can act as a negative transregulator of adenine nucleotide synthesis. IMPDH has also been shown to bind nucleic acids, and this function can be impaired by mutations that are located in the subdomain. The CBS subdomain has also been implicated in mediating IMPDH association with polyribosomes, which suggests a potential moonlighting role for IMPDH as a translational regulatory protein.
The forest is administered by Quebecʻs Ministry of Natural Resources, Wildlife and Parks, Forest Environment Directorate. It was designated old-growth forest in 2003, and has IUCN management category III. A map of the ecological regions of Quebec shows the Sainte-Marguerite River as the boundary between the fir/yellow birch bioclimatic subdomain to the southwest, and the fir/white birch subdomain to the northeast. Technically, the forest is in the latter subdomain.
There are only a few small forests of this type recognized in Quebec. The other type of rare forest is composed of flora that would not normally be found in its bioclimatic subdomain. These are mainly isolated ecosystems in an unusual subdomain in the north.
They are not official hierarchies; they are domains owned by companies who offer free subdomain registration.
Which brings us to domain decomposition methods. If we split the domain [0,1] × [0,1] into two subdomains [0,0.5] × [0,1] and [0.5,1] × [0,1], each has only half of the sample points. So we can try to solve a version of our model problem on each subdomain, but this time each subdomain has only 32 sample points. Finally, given the solutions on each subdomain, we can attempt to reconcile them to obtain a solution of the original problem on [0,1] × [0,1].
Typically TV Sites are differentiated from other web sites by having a "wtv." rather than a "www." subdomain.
On western Eyre Peninsula, the Coulta Subdomain merges with the Nuyts Subdomain which is dominated by variably deformed ca. 1670–1610 Ma granitoids, mafics and felsic volcanics. Deformation is attributed to the Kalaran Orogeny which generated a major fold belt or shear zone, the Fowler Shear Zone, ca. 1600–1540 Ma.
More generally, on each subdomain, the coarse space needs to only contain the nullspace of the problem as a subspace.
A map of the ecological regions of Quebec shows the Nabisipi River Old Forest in the east spruce/moss subdomain.
This gene encodes a 100 kDa homodimer with a regulatory N-terminal domain (1-475), catalytic C-terminal domain (residues 476-917), and an alpha-helix connecting its two subunits. Both terminal domains are composed of a large subdomain and a small subdomain. The flexible region of the C-terminal large subdomain (residues 766–810) can adopt various positions and is proposed to interact with the base of ATP. Moreover, glucose and G6P bind in close proximity at the N- and C-terminal domains and stabilize a common conformational state of the C-terminal domain.
Ribonuclease E function in tetrameric conformation, which contains four subunits associate with each other to create a structure that looks like two scissors connected at the handle region. The scissor blade is made of a large domain, and the handle is made of the small domain. In the catalytic site of the large domain, there are four subdomains that include an RNase H subdomain, a DNase I subdomain, an S1 subdomain, and a 5’ sensing region. These four subunits are divided base on their function and similarity to homologous structural folds.
A map of the ecological regions of Quebec shows the lake is in sub-region 6j-S of the east spruce/moss subdomain.
Note that a subdomain can publish its own DMARC record; receivers must check it out before falling back to the organizational domain record.
A Fully Qualified Domain Name consists of multiple parts. For example, the english wikipedia domain: `en.wikipedia.org` The `en` is a subdomain. Although `wikipedia.
Finally, the subdomain corrections and the coarse correction are added and the sum is averaged across the subdomain interfaces, with the same weights as were used to distribute the forces to the subdomain earlier. This gives the value of the output of BDDC on the interfaces between the subdomains. The values of the output of BDDC in the interior of the subdomains are then obtained by repeating the interior correction. In a practical implementation, the right- hand-side and the initial approximation for the iterations are preprocessed so that all forces inside the subdomains are zero.
The anchor of the RNase E to the 5′-monophosphorylated end of these substrates orients the enzyme for directional cleavages that occur in a processive mode. In the absence of RNA, the S1 subdomain and 5′ sensing site of RNase E are both exposed to the surrounding solvent, allowing RNA to bind readily. In the presence of RNA, target RNA binds to the combined S1 subdomain and 5′ sensor in the open configuration. The RNA is anchored primarily by the binding affinity of the 5′ sensor and oriented by the hydrophobic surface patch on the S1 subdomain.
The top-level domain io has existed since 1997. The first subdomain was registered in 1998, when Levi Strauss & Co. registered the domain levi.io.
The www subdomain contains the directories for the webpages. Independent authentication for each domain provides access control over the various levels of the domain.
Salem Hills High School's address is 150 North Skyhawk Boulevard, Salem Utah 84653. They are also available at shhs.nebo.edu, a subdomain of the district's website.
Subdomain II also contains the dimerization loop required for dimer formation. The cytoplasmic domain contains a juxtamembrane segment, a kinase domain, and a C-terminal domain. Unliganded receptor adopts a conformation that inhibits dimerization. Binding of neuregulin to the ligand binding subdomains (I and III) induces a conformational change in ErbB3 that causes the protrusion of the dimerization loop in subdomain II, activating the protein for dimerization.
For example, a university might assign "cs" to the computer science department, such that a number of hosts could be used inside that subdomain, such as `www.cs.example.edu`. There as some widely recognized subdomains including www, ftp. This allows for a structure where the domain contains administrative directories and files including the ftp directories and webpages. The ftp subdomain can contain logs and the web page directories.
WNK3 is a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase 3 dependent pathway.
He then created the blog. The site's full title of Source Code in TV and Films is sometimes shortened to MovieCode, that being the Tumblr subdomain.
Drummond began blogging in May 2006, initially using the subdomain pioneerwoman.typepad.com within the Typepad blogging service. She registered her own domain – thepioneerwoman.com – on October 18, 2006.
A map of the ecological regions of Quebec shows the Pigou River in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
The Middleback Range is part of the Cleve Subdomain of the Gawler Craton. The iron ore deposits are primarily of Early Proterozoic metasediments of the Hutchison Group.
If orthodenticle is not expressed, structures from the lateral subdomain will be expressed all the way over the head - meaning that ocelli are not produced, i.e. ocelliless.
Payson High School is located at 1050 S. Main St., Payson, Utah 84651. It can also be found online at phs.nebo.edu, a subdomain of the district site.
Unlike both the zinc-binding domains, and the RNA polymerase domains, the C-terminal domains of DNA primases are not conserved. In prokaryotic primases, the only known function of this domain is to interact with the helicase, DnaB. Thus, this domain is called the helicase binding domain (HBD). The HBD of DnaG consists of two subdomains: a helical bundle, the C1 subdomain, and a helical hairpin, the C2 subdomain.
Studies have shown that humans can be infected with MERS-CoV via direct or indirect contact within infected dromedary camels, while human-human transmission is limited. MERS-CoV gains cellular entry by using a spike surface protein to bind to the host DPP4 surface receptor; the core subdomain of this spike surface protein shares similarities with that of SARS-CoV, but its receptor binding subdomain (RBSD) significantly differs.
Leading- order simplification techniques are used in conjunction with the method of matched asymptotic expansions, when the accurate approximate solution in each subdomain is the leading-order solution.
Internet service providers frequently assign the root of a subdomain server to a directory within the master domain server root with a similar (but not necessarily identical) name.
Serine/threonine-protein kinase WNK2 is an enzyme that in humans is encoded by the WNK2 gene. The protein encoded by this gene is a cytoplasmic serine- threonine kinase that contains cysteine in place of the lysine found at the conserved ATP-binding location in subdomain II of protein kinases. Since this protein does have kinase activity, it is possible that another lysine in the kinase subdomain I can substitute for the missing conserved lysine.
While the S1 subdomain is acting to orient the molecule, the 5′ sensing pocket likely contributes a significant portion of the substrate-binding affinity. These two sites hold the RNA while the fusion 5/S1 subdomain moves as a single complex into the closed configuration. It brings the substrate into proximity to the catalytic site where a hydroxyl group attacks the phosphate backbone by nucleophilic attack reaction. This response is mediated by magnesium ion.
A doppelganger domain is a domain spelled identical to a legitimate fully qualified domain name (FQDN) but missing the dot between host/subdomain and domain, to be used for malicious purposes.
In primal methods, such as Balancing domain decomposition and BDDC, the continuity of the solution across subdomain interface is enforced by representing the value of the solution on all neighboring subdomains by the same unknown. In dual methods, such as FETI, the continuity of the solution across the subdomain interface is enforced by Lagrange multipliers. The FETI-DP method is hybrid between a dual and a primal method. Non-overlapping domain decomposition methods are also called iterative substructuring methods.
In primal methods, such as Balancing domain decomposition and BDDC, the continuity of the solution across subdomain interface is enforced by representing the value of the solution on all neighboring subdomains by the same unknown. In dual methods, such as FETI, the continuity of the solution across the subdomain interface is enforced by Lagrange multipliers. The FETI- DP method is hybrid between a dual and a primal method. Non-overlapping domain decomposition methods are also called iterative substructuring methods.
The school's colors are red and blue, and its slogan is "Dedicated to Excellence - United in Service - Educated for Success". The school's web address is shs.nebo.edu, a subdomain of the district's site.
The western subdomain is drier than the eastern subdomain, and the northern red oak (Quercus rubra) is more common in the east. The maple / yellow birch domain covers the slopes and hills that border the southern Laurentian plateau and the Appalachians, and is the most northern domain of the deciduous forest sub-zone. The flora are less diverse and include many boreal species. On representative sites the yellow birch (Betula alleghaniensis) is one of the main companions to the sugar maple.
This gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 (Hsp70) family. As a Hsp70 protein, it has a C-terminal protein substrate-binding domain and an N-terminal ATP-binding domain. The substrate- binding domain consists of two subdomains, a two-layered β-sandwich subdomain (SBDβ) and an α-helical subdomain (SBDα), which are connected by the loop Lα,β. SBDβ contains the peptide binding pocket while SBDα serves as a lid to cover the substrate binding cleft.
In each iteration, it combines the solution of local problems on non-overlapping subdomains with a coarse problem created from the subdomain nullspaces. BDD requires only solution of subdomain problems rather than access to the matrices of those problems, so it is applicable to situations where only the solution operators are available, such as in oil reservoir simulation by mixed finite elements.L. C. Cowsar, J. Mandel, and M. F. Wheeler, Balancing domain decomposition for mixed finite elements, Math. Comp., 64 (1995), pp. 989-1015\.
The subdomain tension-like N terminal function has not yet determined, though the domain shares high homology to the tumor suppressant PTEN. The key characteristic is the cysteine group which is required for phosphorylation; however the tension-like N terminal subdomain is absent of some important functional residues that PTEN has. The C-terminal J domain is responsible for the interaction with Hsc70, which is a molecular chaperone responsible for the uncoating of clathrin-coated vesicles during endocytosis. The clathrin-binding domain gathers clathrin into baskets.
On February 17, 2006, the Finnish parliament approved a modification of the laws regulating Finnish domain names to include the .ax top-level domain. During a three-year period, the aland.fi subdomain was phased out while .
In January 2009, the company created a question and answer website named "Wikianswers". In March 2010, Wikia re-launched "Answers from Wikia", where users could create topic-specialized knowledge market wikis based upon Wikia's own Wikianswers subdomain.
Registrations are permitted directly at the second level, but there is also a .com.aw subdomain intended for commercial sites. Most of registrations are made via SETARNET's website via www.setar.aw There has also been an increase in .pro.
AppArmor was first used in Immunix Linux 1998–2003. At the time, AppArmor was known as SubDomain, a reference to the ability for a security profile for a specific program to be segmented into different domains, which the program can switch between dynamically. AppArmor was first made available in SLES and openSUSE and was first enabled by default in SLES 10 and in openSUSE 10.1. In May 2005 Novell acquired Immunix and rebranded SubDomain as AppArmor and began code cleaning and rewriting for the inclusion in the Linux kernel.
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 (Hsp70) family. As a Hsp70 protein, it has a C-terminal protein substrate-binding domain and an N-terminal ATP-binding domain. The substrate-binding domain consists of two subdomains, a two-layered β-sandwich subdomain (SBDβ) and an α-helical subdomain (SBDα), which are connected by the loop Lα,β. SBDβ contains the peptide binding pocket while SBDα serves as a lid to cover the substrate binding cleft.
The lake is about east of the Romaine 3 Reservoir. A map of the ecological regions of Quebec shows the lake on the border between sub- regions 6j-S and 6n-T of the east spruce/moss subdomain.
The domains are digitally signed using Domain Name System Security Extensions (DNSSEC). The zone files of each domain also define one subdomain name. The third-level domain name www resolves to the IP addresses of the parent domains.
The method was further improved by enforcing the equality of averages across the edges or faces on subdomain interfacesC. Farhat, M. Lesoinne, and K. Pierson, A scalable dual-primal domain decomposition method, Numer. Linear Algebra Appl., 7 (2000), pp.
HdeB, which is encoded within the same operon, may form heterodimers with HdeA. HdeA is a single domain protein with an overall fold that is similar to the fold of the N-terminal subdomain of the GluRS anticodon-binding domain.
Wikidot became a finalist and first prize winner in the AWS Global Start-Up Challenge of 2012 under the category of Consumer Applications. Wikidot uses an open source modified Text_Wiki software (engine). Each site gets a subdomain on .wikidot.com (like mywiki.wikidot.com).
The principal is currently DeAnn Nielsen, and Jeff Nelson and Shea Bradshaw are the Assistant Principals. Maple Mountain High School's address is 51 North Spanish Fork Parkway, Spanish Fork, Utah 84660. It also operates mmhs.nebo.edu a subdomain of the district's website.
The collagen IV C4 domain contains 12 cysteines, and all of them are involved in disulphide bonds. It folds into a tertiary structure with predominantly beta-strands. The collagen IV C4 domain is composed of two similarly folded subdomains stabilised by 3 intrachain disulphide bonds involving the following pairs: C1-C6, C2-C5, and C3-C4. Each subdomain represents a compact disulphide-stabilised triangular structure, from which a finger-like hairpin loop projects into an incompletely formed six-stranded beta-sheet of an adjacent subdomain of the same or of an adjacent chain clamping the subdomains tightly together.
The central domain and the N-terminal domain form a shallow cleft, which makes up the active site of the RNA chain elongation in DnaG. The opening of the cleft is lined by several highly conserved basic residues: Arg146, Arg221, and Lys229. These residues are part of the electrostatically positive ridge of the N-terminal subdomain. It is this ridge that interacts with the ssDNA and helps guide it into the cleft, which consists of the metal binding center of the toprim motif on the central subdomain, and the conserved primase motifs of the N-terminal domain.
The formiminotransferase (FT) domain of formiminotransferase-cyclodeaminase (FTCD) forms a homodimer, with each protomer comprising two subdomains. The formiminotransferase domain has an N-terminal subdomain that is made up of a six-stranded mixed beta-pleated sheet and five alpha helices, which are arranged on the external surface of the beta sheet. This, in turn, faces the beta-sheet of the C-terminal subdomain to form a double beta-sheet layer. The two subdomains are separated by a short linker sequence, which is not thought to be any more flexible than the remainder of the molecule.
The local problems on different subdomains are completely independent of each other, so the method is suitable for parallel computing. With a proper choice of the coarse degrees of freedom (corners in 2D, corners plus edges or corners plus faces in 3D) and with regular subdomain shapes, the condition number of the method is bounded when increasing the number of subdomains, and it grows only very slowly with the number of elements per subdomain. Thus the number of iterations is bounded in the same way, and the method scales well with the problem size and the number of subdomains.
Lys264 is most likely involved in neutralizing the negative charge that develops on phosphate, and it may also serve as a general base (hydrogen acceptor) for the 3'OH of IP3. The structure of the catalytic domain of the human ITP3KA has been shown to be divided into three subdomains. These subdomains are displayed as the N lobe, which is a N-terminal domain, the C lobe, which is a C-terminal subdomain and a third alpha-only subdomain. The ITP3K catalytic domain varies somewhat from the protein kinase superfamily, and it has a novel four-helix substrate binding domain.
The river basin include part of the proposed Basses Collines du Lac Guernesé Biodiversity Reserve. A map of the ecological regions of Quebec shows the river in sub-regions 6o-T, 6n-T and 6m-S of the east spruce/moss subdomain.
The Office also granted request for the reexamination of Hoshiko's (Ideaflood) patent #6,687,746 that covers the automation of subdomain registration. On February 4, 2009, The United States Patent and Trademark Office upheld NeoMedia patent #6,199,048, although with limitations imposed upon the claimed material.
It covers an area of nearly . At this point the Romaine River defines the border between Quebec and Labrador. A map of the ecological regions of Quebec shows the lake in the sub-region 7c-T of the east spruce/lichen subdomain.
DMARC records are published in DNS with a subdomain label `_dmarc`, for example `_dmarc.example.com`. Compare this to SPF at `example.com`, and DKIM at `selector._domainkey.example.com`. The content of the TXT resource record consists of `name=value` tags, separated by semicolons, similar to SPF and DKIM.
In January 2011, Ryan Kirkman and Thomas Davis created the service, launching it on GitHub on February 25, 2011. It initially served content through Amazon CloudFront. On June 15, 2011, cdnjs partnered with Cloudflare, who provided the CDN and subdomain cdnjs.cloudflare.com for the project.
List of Wikipedias The largest, the English Wikipedia, has over million articles. , according to Alexa, the English subdomain (en.wikipedia.org; English Wikipedia) receives approximately 57% of Wikipedia's cumulative traffic, with the remaining split among the other languages (Russian: 9%; Chinese: 6%; Japanese: 6%; Spanish: 5%).
This is a list of organizations with `INT` domain names, in alphabetical order of the second-level domain name. The list is not comprehensive. As of June 2012, the `INT` domain consists of 166 subdomain delegations. These organizations are generally international organizations established by treaty.
The overall structure is held together by 5 parallel β-sheets that are adjacent to 4 α-helices, with 2 being long and 2 being short. A subdomain, containing 2 smaller α-helices, encompasses the area that connects to the C-terminal RFK module.
Second-level domain names must be at least three letters long. Two-letter subdomain names are restricted to the Swiss cantons, as well as the domain ch.ch of the Federal Chancellery of Switzerland. The only exception has been the former domain of the Expo.
All IRAK family members are multidomain proteins consisting of a conserved N-terminal Death Domain (DD) and a central kinase domain (KD). The DD is a protein interaction motif that important for interacting with other signaling molecules such as the adaptor protein MyD88 and other IRAK members. The KD is responsible for the kinase activity of IRAK proteins and consists of 12 subdomains. All IRAK KDs have an ATP binding pocket with an invariable lysine residue in subdomain II, however, only IRAK-1 and IRAK-4 have an aspartate residue in the catalytic site of subdomain VI, which is thought to be critical for kinase activity.
This gene encodes a 70kDa heat shock protein and is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. The amino acid sequence of the encoded protein shares a 90% homology to the isoforms HSPA1A and HSPA1B. As a Hsp70 protein, it has a C-terminal protein substrate-binding domain and an N-terminal ATP-binding domain. The substrate-binding domain consists of two subdomains, a two-layered β-sandwich subdomain (SBDβ) and an α-helical subdomain (SBDα), which are connected by the loop Lα,β.
Average annual temperature is from . A map of the ecological regions of Quebec shows the river in sub- regions 6j-T and 6m-T of the east spruce/moss subdomain. Vegetation includes boreal forest with virgin stands of black spruce (Picea mariana) and balsam fir (Abies balsamea).
On November 10, 2010, TV by the Numbers announced that they were partnering with TV news website Zap2it. As a result, the website's URL changed to a subdomain of the zap2it.com domain. In addition, Zap2it features such as TV listings began to appear on the site.
It is normally found as a standalone domain in bacterial and viral Holliday Junction Resolvases (HJR). FAN1 does not exhibit any activity on Holliday Junction (HJ) substrates. A subdomain of SAP consisting of six α helices connected to the VRR_Nuc region is thought to inhibit HJR activity.
Compared to Domain Authority which determines the ranking strength of an entire domain or subdomain, Page Authority measures the strength of an individual page.Moz - Page Authority It's a score developed by Moz on a 100-point logarithmic scale. Unlike TrustFlow, domain authority does not account for spam.
RNase H is located at the beginning of N-terminal and named after the RNase H endoribonuclease family since they share a similar structure; however, RNase H serves as a structural function rather than catalytic function because it is lack of active-site residue. Next, the S1 subdomain and 5’ sensing region are implanted in RNase H fold. The RNase E S1 domain adopts an OB-fold in which flexible loops are attached to a well- ordered five-stranded β-barrel core. In the ribonuclease E, the S1 domain not only aids in the formation of the tetrameric quaternary structure by dimerization but also serves as a substrate-binding site to facilitate RNA hydrolysis by the catalytic domains within this tetrameric enzyme. With S1 subdomain, 5’ sensing region functions as a substrate-binding site that helps to stabilize the target RNA molecule on one subunit so that the other subunit within a dimer can cleave the RNA of interest. The 5’ sensing region located at a distance from the catalytic site, which resides on the DNase I subdomain.
In mid-2014, a side project website called VinylHub was started for users to add world-wide information about record stores including location, contact details, what type of items they stocked, et al. In August 2020 it was relocated as part of the main Discogs website, under subdomain vinylhub.discogs.com.
Conjugating each subdomain to a different protein allows protein-protein interactions to be studied, because cAMP production indicates close interaction of the proteins. Similarly, the two subdomains can be linked by a studied protein, which is then digested by proteases. Loss of cAMP production indicates cleavage by protease.
Gonk!. In January 2003 set up the first incarnation of "Stageleft: Life on the Left Side" on the free Blogspot hosting service. In March 2003, Stageleft (the blog) moved to a subdomain of crow.ws using the PMachine blogging software. Stageleft eventually moved to its current domain of stageleft.info.
This tells the browser to use the cookie only when requesting pages contained in `docs.foo.com/accounts` (the domain is derived from the request domain). The other two cookies, `HSID` and `SSID`, would be used when the browser requests any subdomain in `.foo.com` on any path (for example `www.foo.com/bar`).
It is about long and very deep. It is bordered on each side by capes and mountains. It is full of large pike. A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
In his 1981 dissertation, Clinger showed how sequential computations form a subdomain of concurrent computations: :Instead of beginning with a semantics for sequential programs and then trying to extend it for concurrency, Actor semantics views concurrency as primary and obtains the semantics of sequential programs as a special case. :... :The fact that there exist increasing sequences without least upper bounds may seem strange to those accustomed to thinking about the semantics of sequential programs. It may help to point out that the increasing sequences produced by sequential programs all have least upper bounds. Indeed, the partial computations that can be produced by sequential computation form an ω-complete subdomain of the domain of Actor computations .
The carboxy-terminal subdomain (CDC48_2) forms a novel six-stranded beta-clam fold. Together these subdomains form a kidney-shaped structure, in close agreement with results from electron microscopy. CDC48_N is related to numerous proteins including prokaryotic transcription factors, metabolic enzymes, the protease cofactors UFD1 and PrlF, and aspartic proteinases.
A map of the ecological regions of Quebec shows the river in sub-regions 6n-T and 6m-T of the east spruce/moss subdomain. Along the river the vegetation is sparse due to the harsh climate and strong winds, and in some areas the gneiss and granite bedrock is exposed.
The mouth of the river is in the municipality of Baie-Johan-Beetz in the Minganie Regional County Municipality. The origin of the name is unknown. A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
The forest is administered by Quebecʻs Ministry of Natural Resources, Wildlife and Parks, Forest Environment Directorate. It was designated old-growth forest in 2005, and has IUCN management category III. A map of the ecological regions of Quebec shows the Lac Auger Old Forest in the east spruce/moss subdomain.
Dolphin users can choose from five subscription plans when building their website or online store with, including a free plan and four premium plans. Dolphin’s free plan, Play, includes many basic features included in the paid plans. Play customers get a personalized subdomain (e.g. www.yourwebsite.jimdosite.com), HTTPS encryption, and up to 5 website pages.
The alpha 3 type VI chain has been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Microfibril formation has been traced to interactions between its N-terminal subdomain N5 and its C-terminal C5 domain in adjacent type VI collagen monomers.
Depending on application, a record inside a domain, or subdomain might refer to a hostname, or a service provided by a number of machines in a cluster. Some websites use different subdomains to point to different server clusters. For example, `www.example.com` points to Server Cluster 1 or Datacentre 1, and `www2.example.
Early in Wikipedia's development, it began to expand internationally, with the creation of new namespaces, each with a distinct set of usernames. The first subdomain created for a non-English Wikipedia was deutsche.wikipedia.com (created on Friday 16 March 2001, 01:38 UTC), followed after a few hours by Catalan.wikipedia.com (at 13:07 UTC).
While the sequence of SVV's protein-coding genome is most similar to members in the Cardiovirus genus, the non-coding RNA internal ribosome entry site (IRES) is most similar to those of the Pestivirus genus, including classical swine fever virus, and Hepacivirus genus, including Hepatitis C virus. The SVV IRES RNA shares similarities in sequence, structure, and function with the hepatitis C virus IRES. Subdomain IIa of the SVV and HCV IRES shares a similar structure and ligand-binding function as seen in its crystal structure. This subdomain IIa region is classified as a ligand-responsive RNA switch which adopts well- defined ligand-free and bound conformations without breaking or forming any base pairs in its secondary structure upon interconversion between the two states.
This is like cross-site cookie, except that it does not rely on browser vulnerabilities. Rather, it relies on the fact that wildcard cookies can be set by one subdomain that affect other subdomains. Scenario: # A web site `www.example.com` hands out subdomains to untrusted third parties # One such party, Mallory, who now controls `evil.example.
The highest point is . The river basin include part of the proposed Basses Collines du Lac Guernesé Biodiversity Reserve. A map of the ecological regions of Quebec shows the river in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain. The river is recognized as an Atlantic salmon river.
The structure of the C-terminal DUF1608 domain of the Methanosarcinales S-layer Tile Protein MA0829. A, the C-terminal DUF1608 domain of MA0829 with domain I colored red, domain II in blue, and the connector subdomain in yellow. B, the crystallographic dimer of the MA0829 CTR. C, a trimer of crystallographic CTR homodimers.
Web sites generally are a subdomain of tripod.com. However, users can pay a monthly charge and own a domain name. Paying in this manner also allows for other benefits, such as more disk space for the site which allows the site owner to put more information onto it, and personalized email accounts, e.g., [email protected].
The river basin covers . The river flows along the contact zone between rocks of the Anorthositic Suite of Havre-Saint-Pierre to the north, and deformed rocks to the south. A map of the ecological regions of Quebec shows the river on the border between sub-regions 6j-S and 6n-T of the east spruce/moss subdomain.
The domain was created in 1990, following the mitigation of the COCOM embargo on technological collaboration with post-communist countries. The first subdomain in was , belonging to the Wrocław University of Technology. In 2008 the number of registered .pl domain names exceeded one million, whereas at the end of 2013 the registry comprised more than 2.4 million domain names.
According to the www.nic.um site at that time, the TLD was no longer affiliated with USC-ISI and had spun off the venture into an independent company, USMIR, which has the same contact information as that of the limited liability company EP.net. Accessing the website without the "www" subdomain returned a copy of the main site for EP.net. Some .
A 3-dimensional convex polytope. Convex analysis includes not only the study of convex subsets of Euclidean spaces but also the study of convex functions on abstract spaces. Convex analysis is the branch of mathematics devoted to the study of properties of convex functions and convex sets, often with applications in convex minimization, a subdomain of optimization theory.
The code `eh`, although eligible as ccTLD for Western Sahara, has never been assigned and does not exist in DNS. Only one subdomain is still registered in `gb` (ISO 3166-1 for the United Kingdom), and no new registrations are being accepted for it. Sites in the United Kingdom generally use `uk` (see below). The former .
RFC 1035, Domain names--Implementation and specification, P. Mockapetris (Nov 1987) Most domain registries only allocate a two-level domain name. Hosting services typically provide DNS Servers to resolve subdomains within that master domain. Subdomains in this context are defined by editing the DNS zone file pertaining to the parent domain. However, there is an ongoing debate over the use of the term “subdomain” when referring to names which map to the Address record A (host) and various other types of zone records which may map to any public IP address destination and any type of server. Network Operations teams insist that it is inappropriate to use the term “subdomain” to refer to any mapping other than that provided by zone NS (name server) records and any server-destination other than that.
Lake Magpie is in the unorganized territory of Lac-Jérôme in the Minganie Regional County Municipality. It can only be reached by float plane. A map of the ecological regions of Quebec shows the lake in sub-region 6j-S of the east spruce/moss subdomain. The lake is named for the Canada jay (Perisoreus canadensis), a bird closely related to the magpie.
Invoicera is an online invoicing software. The software was created by a company with the same name that was founded in 2006, had 125 employees, and is based in India. It allows users to monitor, dispatch, and accept invoices in one web service. After signing up for the service, users are assigned a personal subdomain to set up their invoice configuration.
The basin covers . It lies between the basins of the Nabisipi River to the west and the Natashquan River to the east. It is partly in the unorganized territory of Lac-Jérôme, partly in the municipality of Aguanish. A map of the ecological regions of Quebec shows the river in sub- regions 6j-T and 6m-T of the east spruce/moss subdomain.
A map of the ecological regions of Quebec shows the river in sub-regions 6o-T, 6n-T and 6m-S of the east spruce/moss subdomain. Land cover in the watershed is 74.3% forest, 12.9% non-forest vegetation, 3.1% barren, 1.3% wetlands and 8% water. Average daily mean temperature is , ranging from in January to in July. Annual total precipitation is .
A map of the ecological regions of Quebec shows the Napetipi River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain. 85.4% of the watershed is forested, and 3.5% has other forms of dry land vegetation. 8.3% is water covered, and 1.2% is wetlands. Annual daily mean temperature is , ranging from in January to in July.
April 2016] In addition to exclusive productions, anime and US productions were also aired. On RTL II You the news format RTL II News as well as the weather of RTL II were broadcast. RTL II You also worked with some YouTube stars and channels, whose content was also added to the channel. The channel was accessible via the subdomain you.rtl2.
Figure 3: Modules and Domains for Tyrocidine biosynthesis Each module performs all the catalytic reactions necessary to incorporate a single amino acid onto the peptide chain. This is accomplished through the subdomains for adenylation (A), peptityl carrier protein (PCP), condensation (C), and depending on the amino acid position, an epimerization (E). The adenylation subdomain is used in activating the specific amino acid.
The was a feudal domain in Mutsu Province of Japan (present-day Mizusawa-ward, Ōshū, Iwate) during the Edo period. It was a subdomain (支藩) of the Sendai Domain. Sometimes it was suggested that the domain be called "Naka-Tsuyama han" (中津山藩). The domain as a separate entity was ultimately short-lived, eventually being reabsorbed into Sendai territory.
A central eight-stranded beta-pleated sheet makes up the main feature of the polypeptide backbone folding of DHFR. Seven of these strands are parallel and the eighth runs antiparallel. Four alpha helices connect successive beta strands. Residues 9 – 24 are termed "Met20" or "loop 1" and, along with other loops, are part of the major subdomain that surround the active site.
A subdomain of a division ring which is not right or left Ore: If F is any field, and G = \langle x,y \rangle\, is the free monoid on two symbols x and y, then the monoid ring F[G]\, does not satisfy any Ore condition, but it is a free ideal ring and thus indeed a subring of a division ring, by .
Subdomains are often used by internet service providers supplying web services. They allocate one (or more) subdomains to their clients who do not have their own domain name. This allows independent administration by the clients over their subdomain. Subdomains are also used by organizations that wish to assign a unique name to a particular department, function, or service related to the organization.
The forest is in the watershed of the Watshishou River. The forest is administered by Quebecʻs Ministry of Natural Resources, Wildlife and Parks, Forest Environment Directorate. It was designated old-growth forest in 2009, and has IUCN management category III. A map of the ecological regions of Quebec shows the Nabisipi River Old Forest in the east spruce/moss subdomain.
The Rivière-au-Tonnerre weather station, from the mouth of the Jupitagon, reports an annual average temperature of and annual average rainfall of . Temperatures would be lower inland. A map of the ecological regions of Quebec shows the Jupitagon in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. Black spruce (Picea mariana) forest dominates the coastal plain.
It was designated a rare forest ecosystem in 2003, and has IUCN management category III. A map of the ecological regions of Quebec shows the Forestville region in the 5g-T ecological subregion of the east fir/white birch subdomain. The Laval River area is dominated by stands of balsam fir (Abies balsamea). The soil consists of glacial deposits, with many rocky outcrops.
The crystal structure of primase in E. coli with a core containing the DnaG protein was determined in the year 2000. The DnaG and primase complex is cashew shaped and contains three subdomains. The central subdomain forms a toprim fold which is made of a mixture five beta sheets and six alpha helices. The toprim fold is used for binding regulators and metals.
Only a single level of subdomain matching is supported in accordance with .Wildcard SSL certificate limitation on QuovadisGlobal.com It is not possible to get a wildcard for an Extended Validation Certificate. A workaround could be to add every virtual host name in the Subject Alternative Name (SAN) extension,x509v3_config Subject Alternative NameThe SAN option is available for EV SSL Certificates on Symantec.
Overview of the flavivirus RdRp structure based on West Nile Virus (WNV) NS5Pol Viral/prokaryotic RNA-directed RNA polymerases, along with many single-subunit DNA-directed polymerases, employ a fold whose organization has been likened to the shape of a right hand with three subdomains termed fingers, palm, and thumb. Only the palm subdomain, composed of a four-stranded antiparallel beta sheet with two alpha helices, is well conserved among all of these enzymes. In RdRP, the palm subdomain comprises three well-conserved motifs (A, B, and C). Motif A (D-x(4,5)-D) and motif C (GDD) are spatially juxtaposed; the aspartic acid residues of these motifs are implied in the binding of Mg2+ and/or Mn2+. The asparagine residue of motif B is involved in selection of ribonucleoside triphosphates over dNTPs and, thus, determines whether RNA rather than DNA is synthesized.
A map of the ecological regions of Quebec shows the Kécarpoui River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain. Vegetation in the basin is dominated by conifers. Mammals include black bear, moose, boreal woodland caribou, wolf, fox, lynx, muskrat, mink, otter and porcupine. There are seabird colonies on the many islands and islets near the river mouth.
A map of the ecological regions of Quebec shows the Coxipi River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain. About 80.6% of the watershed is forest covered, with just 3.1% covered in shrubs or grassland. 9.6% of the watershed in water and 1.2% wetlands. Annual daily mean temperatures are , ranging from in January to in July.
The German edition of Wikipedia was the first non-English Wikipedia subdomain, and was originally named . Its creation was announced by Jimmy Wales on 16 March 2001. One of the earliest snapshots of the home page, dated 21 March 2001 (revision #9), can be seen at the Wayback Machine site.Internet Archive's snapshots of German Wikipedia HomePage, 21 March 2001 12:10 (revision #9), and related revision history.
LOINC applies universal code names and identifiers to medical terminology related to electronic health records. The purpose is to assist in the electronic exchange and gathering of clinical results (such as laboratory tests, clinical observations, outcomes management and research). LOINC has two main parts: laboratory LOINC and clinical LOINC. Clinical LOINC contains a subdomain of Document Ontology which captures types of clinical reports and documents.
The 3D structure of a monomeric ABC module adopts a stubby L-shape with two distinct arms. ArmI (mainly beta-strand) contains Walker A and Walker B. The important residues for ATP hydrolysis and/or binding are located in the P-loop. The ATP-binding pocket is located at the extremity of armI. The perpendicular armII contains mostly the alpha helical subdomain with the signature motif.
The mouth of the Laval River is in Forestville, La Haute- Côte-Nord. Route 385 roughly follows the course of the river. The Commission de toponymie du Québec does not have information about the name, which was made official on 5 December 1968. A map of the ecological regions of Quebec shows the Laval River in sub-region 5g-T of the east fir/white birch subdomain.
In 2007, the site launched "click-to-record" functionality allowing users with TiVo digital video recorders to remotely schedule recordings directly from within the Zap2it television listings. The site launched TVOvermind, a blog dedicated to episodic recaps hosted as a subdomain on the Zap2it website, in 2008. It was later purchased by BC Media Group in 2012. On October 3, 2016, the site was rebranded as Screener.
Each monomer consists of five alpha helices surrounding five beta sheets. Of these, two antiparallel beta sheets and one alpha helix are located in a subdomain where the N-terminus and C-terminus are in close juxtaposition. The homohexamer exhibits a threefold axis perpendicular to a twofold axis. Within the wide V-groove, there are twelve hydrogen bonds and six salt bridges between the monomers in the presence of phosphate binding.
The Sheldrake River basin is partially in the unorganized territory of Lac-Jérôme, partly in the municipality of Rivière-au-Tonnerre. The river basin covers . It lies between the basins of the Chaloupe River to the west and the Tonnerre River to the east. A map of the ecological regions of Quebec shows the river basin in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
Part of the river basin is in the unorganized territory of Lac-Jérôme and part in the municipality of Aguanish. The river basin covers . It lies between the basins of the Little Watshishou River to the west and the Nabisipi River to the east. A map of the ecological regions of Quebec shows the river basin in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
The river basin covers . It lies between the basins of the Coxipi River to the west and the Napetipi River to the east. It is partly in the unorganized territory of Petit-Mécatina and partly in the municipality of Saint-Augustin. A map of the ecological regions of Quebec shows the river in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain.
The river basin covers . It lies between the basins of the Sheldrake to the west and the Jupitagon to the east. Part of the basin is in the unorganized territory of Lac-Jérôme and part in the municipality of Rivière-au-Tonnerre. A map of the ecological regions of Quebec shows the river basin is in sub-regions 6j-S, 6j-T and 6m-T of the east spruce/moss subdomain.
Instead, a lysine in the β2 strand of subdomain I of the catalytic domain is responsible for the kinase activity. The WNK4 gene is located on chromosome 17q21-q22. It produces a 1,243-amino acid protein encoded by a 3,732-nucleotide open reading frame within a 4 kb cDNA transcript. WNK4 protein is highly expressed in the distal convoluted tubule (DCT) and the cortical collecting duct (CDD) of the kidney.
X-ray crystallographic studies of the N-terminal half of mammalian ZP3 () as well as its full-length avian homolog () revealed that the protein's ZP module consists of two immunoglobulin-like domains, ZP-N and ZP-C. The latter, which contains EHP as well as a ZP3-specific subdomain, interacts with the ZP-N domain of a second molecule to generate an antiparallel homodimeric arrangement required for protein secretion.
The ACE also incorporated the MMSE, such that this score (out of 30) might also be generated. The ACE-R was a development of the earlier ACE which also incorporated the MMSE, but had clearly defined subdomain scores. The ACE-III was developed to improve the performance of certain parts of the test and also to avoid a potential copyright violation by replacing the elements shared with the MMSE.
In numerical analysis, the Schur complement method, named after Issai Schur, is the basic and the earliest version of non-overlapping domain decomposition method, also called iterative substructuring. A finite element problem is split into non-overlapping subdomains, and the unknowns in the interiors of the subdomains are eliminated. The remaining Schur complement system on the unknowns associated with subdomain interfaces is solved by the conjugate gradient method.
Prefixes can be added so subkingdom (subregnum) and infrakingdom (also known as infraregnum) are the two ranks immediately below kingdom. Superkingdom may be considered as an equivalent of domain or empire or as an independent rank between kingdom and domain or subdomain. In some classification systems the additional rank branch (Latin: ramus) can be inserted between subkingdom and infrakingdom, e.g., Protostomia and Deuterostomia in the classification of Cavalier-Smith.
' For a given site, inspecting the individual cookies for the top level name of the site, and any subdomain names, will reveal if 'Send For: Encrypted connections only,' has been set. If it has, the user can test for the site's vulnerability to CookieMonster attacks by deleting these cookies and visiting the site again. If the site still allows the user in, the site is vulnerable to CookieMonster attacks.
NS2 is one of seven nonstructural proteins in HCV, with each being encoded near the carboxy-terminal end of the positive-strand RNA virus. Once translated it is 217 amino acids in length and has a molecular weight of approximately 23 kDa. NS2 possesses a hydrophobic amino-terminal subdomain as well as a carboxy-terminal cytoplasmic domain, with the amino-terminal subdomain containing up to three putative transmembrane segments. NS2 proteins are post-translationally processed by the HPV-encoded cysteine protease NS2-3, which is formed by residues 94-217 of NS2 itself as well as residues 1-181 of nonstructural protein 3 (NS3). The NS2-3 autoprotease acts by making a single cleavage between the junction of NS2 and NS3. While the NS2 protein itself is unnecessary for replication of the HCV virus (as demonstrated by HPV replicons that were able to self-replicate after removal of the entire C to NS2 coding region), this cleavage of the NS2/NS3 junction is critical.
The Pentecôte weather station, to the southwest of the river mouth, records an average annual temperature of and annual average rainfall of . A map of the ecological regions of Quebec shows the upper and central Dominique River in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain, and the lower part in sub- region 5g-T of the eastern fir/white birch subdomain.. On the coastal plain the forest cover is dominated by stands of balsam fir (Abies balsamea), white spruce (Picea glauca) and paper birch (Betula papyrifera), with lesser numbers of jack pine (Pinus banksiana), larch and trembling aspen (Populus tremuloides). Further inland in the spruce-moss region the forest cover is dominated by black spruce (Picea mariana), with balsam fir and, to a lesser extent, hardwoods such as paper birch, trembling aspen and balsam poplar (Populus balsamifera). Fish species are American eel (Anguilla rostrata) and brook trout (Salvelinus fontinalis).
The Washicoutai River basin covers . It lies between the basins of the Musquanousse River to the west and the Olomane River to the east. It is partly in the unorganized territory of Petit-Mécatina and partly in the municipality of Côte-Nord-du-Golfe-du-Saint-Laurent. A map of the ecological regions of Quebec shows the Washicoutai River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain.
The Musquanousse River basin covers . It lies between the basins of the Musquaro River to the west and the Washicoutai River to the east. It is partly in the unorganized territory of Petit-Mécatina and partly in the municipality of Côte-Nord-du-Golfe-du-Saint-Laurent. A map of the ecological regions of Quebec shows the Musquanousse River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain.
Part of the river basin is in the unorganized territories of Rivière-Nipissis and Lac-Jérôme and part in the municipality of Rivière-au-Tonnerre. The river basin covers . It lies between the basins of the Sault Plat River to the west and the Manitou River to the east. A map of the ecological regions of Quebec shows the river basin in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
The Rivière- au-Tonnerre weather station is east of the river mouth. It records an average annual temperature of and average annual precipitation of . A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. Black spruce (Picea mariana) dominate the forests on the coastal plain, while the piedmont area has mixed black spruce and balsam fir (Abies balsamea).
These eukaryotic nucleotide exchange factors are all heat-shock inducible meaning that they serve a similar function as GrpE, to protect the cell from unfolded protein aggregation. These nucleotide exchange factors always interact with subdomain IIB of the nucleotide binding cleft of their respective heat-shock proteins. The binding of the nucleotide exchange factor to a nucleotide binding cleft and the shift to an open conformation is conserved between prokaryotes and eukaryotes.
The C-terminal subdomain of Villin Headpiece VHP67, denoted VHP35, is stabilised in part, by a buried cluster of three phenylalanine residues. Its small size and high helical content are expected to promote rapid folding, and this has been confirmed experimentally. Villin-4 C-terminal construct VHP76 in Arabidopsis thaliana has been shown to exhibit higher affinity for F-actin in increasing concentrations of Ca2+, which further confirms the function of villin.
This specific binding site consists of subdomain GAF (cGMP-specific cGMP-stimulated PDE, adenylate cyclase, and FhlA) which is located in the N-terminal section of the specific proteins. The allosteric binding site GAF consists of GAFa and GAFb where GAFa has a higher binding affinity. The importance and functional role of the two homologous binding sites are unknown. Conformational change occurs when cGMP binds to the allosteric site that exposes serine and permits phosphorylation.
In 2009, the company began offering free web application hosting. With either their own domain or a free subdomain, customers are able to make use of a number of open source applications, such as WordPress and MediaWiki without charge. The service is similar to, and can be integrated with, the Google App Engine. Through a control panel, customers are able to manage their applications or upgrade to the standard, fully managed hosting service.
Privacy concerns about cookies have therefore led a noticeable minority of users to block or delete third-party cookies. In 2005, some reports showed that about 28% of Internet users blocked third-party cookies and 22% deleted them at least once a month. Most vendors of page tagging solutions have now moved to provide at least the option of using first-party cookies (cookies assigned from the client subdomain). Another problem is cookie deletion.
As In The Groove 2 matured as an arcade game, Roxor released patches, called "revisions", that could be applied to the machine in order to update it, fix bugs, adjust timing window errors, and other issues as they were discovered. This list contains only changes that were officially published by Roxor Games. Their website discussing these Machine Updates, and their respective downloads are still available on the In The Groove subdomain of Roxor Games' website.
For example: "v=DMARC1;p=none;sp=quarantine;pct=100;rua=mailto:[email protected];" Here, `v` is the version, `p` is the policy, `sp` the subdomain policy, `pct` is the percent of "bad" emails on which to apply the policy, and `rua` is the URI to send aggregate reports to. In this example, the entity controlling the example.com DNS domain intends to monitor SPF and/or DKIM failure rates and doesn't expect emails to be sent from subdomains of example.com.
This entry represents a subdomain of the appendage (ear) domain of beta-adaptin from AP clathrin adaptor complexes. This domain has a three-layer arrangement, alpha-beta- alpha, with a bifurcated antiparallel beta-sheet. This domain is required for binding to clathrin, and its subsequent polymerisation. Furthermore, a hydrophobic patch present in the domain also binds to a subset of D-phi-F/W motif-containing proteins that are bound by the alpha-adaptin appendage domain (epsin, AP180, eps15).
The high level of conservation of the AMMECR1 domain points to a basic cellular function, potentially in either the transcription, replication, repair or translation machinery. The AMMECR1 domain contains a six-amino-acid motif (LRGCIG) that might be functionally important since it is strikingly conserved throughout evolution. The AMMECR1 domain consists of two distinct subdomains of different sizes. The large subdomain, which contains both the N- and C-terminal regions, consists of five alpha-helices and five beta-strands.
The subdomain between regions five and six of this domain is known to connect to the intermediate filaments cytokeratin and vimentin. At the opposite end of the protein, in the N-terminal domain, a region has been defined as responsible for binding to actin. In 2004, the exact crystal structure of this actin-binding domain (ABD) was determined in mice and shown to be composed of two calponin homology (CH) domains. Plectin is expressed in nearly all mammalian tissues.
The structure of this enzyme, and several mutants, in complex with the DNA sequence which it cuts has been solved by X-ray crystallography. The core of the enzyme consists of a five-stranded mixed β-sheet flanked by α-helices. The core is conserved in all other type II restriction endonucleases. It also has an N-terminal dimerization subdomain formed by a short α-helix, a two-stranded antiparallel -sheet, and a long α-helix.
Military globalization, as subdomain of political globalization, is defined as the intensification and stretching of military power across the globe through various means of military power (nuclear military weapons, radiation weapons simply weapons of mass destruction). This form of globalization occurs across offensive and defensive uses of power and survival in international field. Beyond states, global organizations such as the United Nations also extend military means globally through support given by both Global North and South countries.
Kuru is largely localized to the Fore people and people with whom they intermarried. The Fore people ritualistically cooked and consumed body parts of their family members following their death to symbolize respect and mourning. Because the brain is the organ enriched in the infectious prion, women and children, who consumed brain and viscera, had much higher likelihood of being infected than men, who preferentially consumed muscles. Normally folded prion protein PrPc subdomain-Residues 125–228.
For computing efficiency, LAMMPS uses neighbor lists (Verlet lists) to keep track of nearby particles. The lists are optimized for systems with particles that repel at short distances, so that the local density of particles never grows too large. On parallel computers, LAMMPS uses spatial-decomposition techniques to partition the simulation domain into small 3d sub-domains, one of which is assigned to each processor. Processors communicate and store ghost atom information for atoms that border their subdomain.
A private sub-domain registry allocates domain names in a subset of the Domain Name System under a domain registered with an ICANN-accredited or ccTLD registry. Most of the private sub-domain registries operate based on an ISO 3166-1 name that is a subdomain of a higher-level domain. Some of these registries combine the domain registry and the domain registrar functions in the administration structure, while others distribute domains via third-party registrars.
Ocelliless (oc) or Orthodenticle is a homeobox gene involved in Drosophila head development. It produces a homeodomain protein which controls the development of cells in the developing head of embryos. It defines the midline of the head, and is involved in the formation of the top side of the head, including the eyes. The gene breaks the head down into subdomains; the medial subdomain (contains the ocelli); the mediolaterial ; and the lateral (just above the compound eyes).
In molecular biology, the CDC48 N-terminal domain is a protein domain found in AAA ATPases including cell division protein 48 (CDC48), VCP-like ATPase and N-ethylmaleimide sensitive fusion protein. It is a substrate recognition domain which binds polypeptides, prevents protein aggregation, and catalyses refolding of permissive substrates. It is composed of two equally sized subdomains. The amino-terminal subdomain (CDC48_N) forms a double-psi beta- barrel whose pseudo-twofold symmetry is mirrored by an internal sequence repeat of 42 residues.
Another feature of Domain 1 is the presence of a carbohydrate binding site that direct the enzyme to bind to extracellular carbohydrates. Domain 2 (residues 156-552) contains the copper binding site. The β-strands in Domain 2 are organized as a seven-fold propeller, and each of the seven structural units is a subdomain consisting of four antiparallel β-strands. Domain 3 (residues 553-639) consists of seven anti-parallel β-strands and forms a “cap” over Domain 2.
These five beta-strands form an antiparallel beta-sheet. The small subdomain consists of four alpha-helices and three beta-strands, and these beta-strands also form an antiparallel beta- sheet. The conserved 'LRGCIG' motif is located at beta(2) and its N-terminal loop, and most of the side chains of these residues point toward the interface of the two subdomains. The two subdomains are connected by only two loops, and the interaction between the two subdomains is not strong.
He died in 1981 and the Eshelby Memorial Bursary was founded in his memory. The scientific phenomenon called "Eshelby's inclusion" is named after this scientist, and points at an ellipsoidal subdomain in an infinite homogeneous body, subjected to a uniform transformation strain. Eshelby was clear and amusing as a lecturer, and prepared his lectures with great care, but was not keen on doing experimental work. He was well versed in Sanskrit (among other classical languages) and was an avid second-hand book buyer.
Dashed lines represent polar contacts. Most IMPDH monomers contain two domains: a catalytic (β/α)8 barrel domain with an active site located in the loops at the C-terminal end of the barrel, and a subdomain consisting of two, repeated cystathionine beta synthetase (CBS) domains that are inserted within the dehydrogenase sequence. Monovalent cations have been shown to activate IMPDH enzymes and may serve to stabilize the conformation of the active-site loop. The CBS domain is not required for catalytic activity.
In order to be active, most CDKs require not only a cyclin partner but also phosphorylation at one particular site, which corresponds to Thr161 in human CDK1, and which is located within the so-called T-loop (or activation loop) of kinase subdomain VIII.Morgan DO: Principles of CDK regulation. Nature 1995, 374:131-134Solomon MJ: The function(s) of CAK, the p34cdc2 activating kinase. Trends Biochem Sci 1994,19:496-500 CDKl, CDK2 and CDK4 all require T-loop phosphorylation for maximum activity.
Low participation lowers the probability that the articles are reviewed, developed and updated, and political polarisation of participants is likely to lead to biases in the articles. According to Alexa Internet, on 26 November 2014, the Arabic Wikipedia is the 10th most visited language version of Wikipedia in terms of percentage of visitors on all of the Wikipedias over a month, with the "ar.wikipedia.org" subdomain attracting approximately 1.8% of the total visitors of the "wikipedia.org" website, despite being ranked no.
The E2 domain is the largest subdomain of APLP2 and consists of six alpha-helixes. The N-terminal double stranded coiled coil structure of the first monomer of E2 packs against the C-terminal triple stranded coiled coil structure of the second monomer. The BPTI/Kunitz inhibitor domain (residues 306-364) is ‘Cys-rich’ and is capable of inhibiting several proteases. The ectodomain of APLP2 is dimeric and contains multiple binding sites for metal ions and components of the extracellular matrix.
A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. The north of the Véronique valley has potential for use by moose (Alces alces), and traces of moose were found in the region in 1978 and 1979. Beaver (Castor canadensis) is well represented in the river basin. The Véronique River has low potential for Canada goose (Branta canadensis) and average potential for surface ducks and diving ducks.
In molecular biology, BpuJI is a type II restriction endonuclease which recognises the asymmetric sequence 5'-CCCGT and cuts at multiple sites in the surrounding area of the target sequence. The BpuJI protein consists of two distinct modules; an N-terminal DNA recognition domain, and a C-terminal dimerisation and catalysis domain. The N-terminal domain is composed of two winged-helix subdomains and a disrupted linker subdomain. Target sequence recognition occurs through major groove contacts of amino acids in the winged- helix subdomains.
Serine/threonine protein kinase WNK4 also known as WNK lysine deficient protein kinase 4 or WNK4, is an enzyme that in humans is encoded by the WNK4 gene. Missense mutations cause a genetic form of pseudohypoaldosteronism type 2, also called Gordon syndrome. WNK4 is a member of a serine/threonine kinase family that comprises of four members. The family is so named because unlike other serine/threonine kinases, WNKs are characterized by the lack of the lysine in the subdomain II of the catalytic domain.
The HTTP request was sent to a webpage within the `docs.foo.com` subdomain: HTTP/1.0 200 OK Set-Cookie: LSID=DQAAAK…Eaem_vYg; Path=/accounts; Expires=Wed, 13 Jan 2021 22:23:01 GMT; Secure; HttpOnly Set-Cookie: HSID=AYQEVn…DKrdst; Domain=.foo.com; Path=/; Expires=Wed, 13 Jan 2021 22:23:01 GMT; HttpOnly Set-Cookie: SSID=Ap4P…GTEq; Domain=foo.com; Path=/; Expires=Wed, 13 Jan 2021 22:23:01 GMT; Secure; HttpOnly … The first cookie, `LSID`, has no `Domain` attribute, and has a `Path` attribute set to `/accounts`.
In its original formulation, BDD performs well only for 2nd order problems, such elasticity in 2D and 3D. For 4th order problems, such as plate bending, it needs to be modified by adding to the coarse problem special basis functions that enforce continuity of the solution at subdomain corners,P. Le Tallec, J. Mandel, and M. Vidrascu, A Neumann- Neumann domain decomposition algorithm for solving plate and shell problems, SIAM Journal on Numerical Analysis, 35 (1998), pp. 836-867\. which makes it however more expensive.
The Matamec weather station, west of the Sault Plat River mouth, reports annual average temperature of and annual average rainfall of . A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. Forest cover consists of black spruce (Picea mariana) and balsam fir (Abies balsamea), with black spruce dominant on the coastal plain and mixed spruce/fir in the piedmont region. The only recorded fish species is brook trout (Salvelinus fontinalis).
Domain decomposition methods solve a boundary value problem by splitting it into smaller boundary value problems on subdomains and iterating to coordinate the solution between adjacent subdomains. A coarse problem with one or few unknowns per subdomain is used to further coordinate the solution between the subdomains globally. The problems on the subdomains are independent, which makes domain decomposition methods suitable for parallel computing. Domain decomposition methods are typically used as preconditioners for Krylov space iterative methods, such as the conjugate gradient method or GMRES.
The Rivière-Saint-Jean weather station, from the mouth of the river, reports an annual average temperature of and annual average rainfall of . A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. Forests are dominated by black spruce (Picea mariana) and balsam fir (Abies balsamea), with a greater ratio of spruce to fir further north. Other tree species include white spruce (Picea glauca), jack pine (Pinus banksiana), paper birch (Betula papyrifera) and trembling aspen (Populus tremuloides).
A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. The forest cover is dominated by black spruce (Picea mariana), balsam fir (Abies balsamea) and to a lesser extent hardwoods such as paper birch (Betula papyrifera), trembling aspen (Populus tremuloides) and balsam poplar (Populus balsamifera). The Rapides River is not recognized as a salmon river. Fish species are rainbow smelt (Osmerus mordax), American eel (Anguilla rostrata), brook trout (Salvelinus fontinalis), ninespine stickleback (Pungitius pungitius) and lake whitefish (Coregonus clupeaformis).
On August 22, 2005, The New York Times reported a rumor of a Google-branded "communications tool" service and the Los Angeles Times provided details. Subsequently, the subdomain was found to have an active XMPP server. Two methods of logging into the server were discovered soon after and the ensuing response by eager bloggers revealed to numerous others how to log in before the official release by Google. On the evening of August 23, many logged-in users using port 5222 to connect were disconnected and unable to log back in.
In 2006 the Russian Ministry of Defence declassified about a hundred of pages of archived documents concerning Soviet preparedness for the German invasion on 22 June 1941 at the Eastern Front of World War II. On 22 June 2017 the Ministry published them online on a subdomain of its official website, stating that they have never been published before. The documents from the early 1950s were authored by Soviet military commanders of various ranks at the request of a fact-finding panel. The online publication was made on the 76th anniversary of Operation Barbarossa.
This domain lies in the center of the SecA protomer and contacts via α-helical interactions all other subdomains. In addition it contains the intramolecular regulator of ATP hydrolysis 1 (IRA1) subdomain which seems to prevent unwanted ATP hydrolysis when SecA is not bound to SecYEG. Together with IRA1, a conserved salt bridge called Gate 1 might function to prevent unnecessary conformational change. Gate 1 seems to functionally connect the nucleotide (ATP) binding site of the DEAD motor domain with the PPXD domain which results in regulation of ATP hydrolysis only upon preprotein binding.
NNRTIs do not bind to the active site of the polymerase but in a less conserved pocket near the active site in the p66 subdomain. Their binding results in a conformational change in the reverse transcriptase that distorts the positioning of the residues that bind DNA, inhibiting polymerization. Mutations in response to NNRTIs decrease the binding of the drug to this pocket. Treatment with a regimen including efavirenz (EFV) and nevirapine (NVP) typically results in mutations L100I, Y181C/I, K103N, V106A/M, V108I, Y188C/H/L and G190A/S.
The key functionality of the DNS exploited here is that different users can simultaneously receive different translations for the same domain name, a key point of divergence from a traditional phone-book view of the DNS. This process of using the DNS to assign proximal servers to users is key to providing faster and more reliable responses on the Internet and is widely used by most major Internet services. The DNS reflects the structure of administrative responsibility in the Internet. Each subdomain is a zone of administrative autonomy delegated to a manager.
Name servers in delegations are identified by name, rather than by IP address. This means that a resolving name server must issue another DNS request to find out the IP address of the server to which it has been referred. If the name given in the delegation is a subdomain of the domain for which the delegation is being provided, there is a circular dependency. In this case, the name server providing the delegation must also provide one or more IP addresses for the authoritative name server mentioned in the delegation.
Posterous also had its own URL shortening service, which as of March 2010 could post to Twitter. Posterous allowed users to point the DNS listing for a domain name or subdomain they already owned to their Posterous account, allowing them to have a site hosted by Posterous that used their own domain name. In January 2010, the3six5, a Posterous-based storytelling project, launched. It was nominated for a Webby Award in 2011. In May 2010, Posterous was recognized as one of the “2010 Hottest Silicon Valley Companies” by Lead411.
In mathematics, the Neumann–Dirichlet method is a domain decomposition preconditioner which involves solving Neumann boundary value problem on one subdomain and Dirichlet boundary value problem on another, adjacent across the interface between the subdomains.O. B. Widlund, Iterative substructuring methods: algorithms and theory for elliptic problems in the plane, in First International Symposium on Domain Decomposition Methods for Partial Differential Equations (Paris, 1987), SIAM, Philadelphia, PA, 1988, pp. 113-128. On a problem with many subdomains organized in a rectangular mesh, the subdomains are assigned Neumann or Dirichlet problems in a checkerboard fashion.
A country code second-level domain is a second-level domain to a country code top-level domain. Such a domain may be reserved by a domain name registry for the registration of third-level domains, or assigned to a third party as a subdomain. Many country code domain registries implement domain name classes at the second level underneath their ccTLD, such as are present in the original generic top-level domains , , and , which were intended for commercial entities, network operators, and non-profit organizations, respectively. Many countries implement additional classes.
In the areas adjacent to the reserve there is an established network of state reserves and natural monuments of regional importance, the protection and administration of which is carried out jointly with the reserve land users. This includes the state nature reserve of federal importance "Kletnyanskoy", with an area of . The animals in the reserve are typical of the southern range of the mixed boreal-forest subdomain of the Palaearctic region: grouse, boreal owl, hare, lynx, brown bear, and others. Bison were brought to the reserve in 2011.
Most top-level domain name registry operators offer their name spaces to the public or to entities with mandated geographic or otherwise scoped purpose for registration of second- level domains. Similarly an organization in charge of a lower level domain may operate its name space similarly and subdivide its space. Each registration or allocation of subdomain space obligates the registrant to maintain an administrative and technical infrastructure to manage the responsibility for its zone, including sub-delegation to lower-level domains. Each delegation confers essentially unrestricted technical autonomy over the allocated space.
RNF144A is an E3 ubiquitin ligase belonging to the RING-between RING (RBR) family of ubiquitin ligases, whose specific members have been shown to function as RING-HECT hybrid E3 ligases. RNF144A is most closely related to RNF144B at the protein level, and the two proteins together comprise a subdomain within the RBR family of proteins. The ubiquitin ligase activity of RNF144A catalyzes ubiquitin linkages at the K6-, K11- and K48- positions of ubiquitin in vitro, and is regulated by self-association through its transmembrane domain. The biological functions of RNF144A is/are relatively unknown beyond its intrinsic enzymatic activity.
Then, the Pi remains bound to the actin next to the ADP for a long time, until it is cooperatively liberated from the interior of the filament. The exact molecular details of the catalytic mechanism are still not fully understood. Although there is much debate on this issue, it seems certain that a "closed" conformation is required for the hydrolysis of ATP, and it is thought that the residues that are involved in the process move to the appropriate distance. The glutamic acid Glu137 is one of the key residues, which is located in subdomain 1.
A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. As of 1966 most of the region had no trees, since a forest fire twenty years earlier had destroyed almost all the vegetation and burned the thin layer of humus that covered the rock. There were some trees remaining along the rivers, mostly balsam fir, spruce, birch and aspen. The area had many beaver, which were trapped by the Indians of the Mingan Reserve, but not so much as to wipe them out.
Laurent series are the complex-valued equivalent to Taylor series, but can be used to study the behavior of functions near singularities through infinite sums of more well understood functions, such as polynomials. A bounded function that is holomorphic in the entire complex plane must be constant; this is Liouville's theorem. It can be used to provide a natural and short proof for the fundamental theorem of algebra which states that the field of complex numbers is algebraically closed. If a function is holomorphic throughout a connected domain then its values are fully determined by its values on any smaller subdomain.
The Quetachou River basin is partially in the unorganized territory of Lac-Jérôme and partially in the municipality of Baie- Johan-Beetz. The basin covers , and lies between the basins of the Piashti River and the Véronique River. Lakes in the watershed include Lac Uhu, Lacs de la Cabane Brûlée, Lac Devost, Lac Croche, Lac Bellanger, Lac Napoléon, Lac Beetz, Lac Noroy, Lac de la Robe Noire, Lac François and Lac Gendron. A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain.
In fact, interlinking your blogs could help Google and a single exposed blog could reveal the whole blog network by looking at the outbound links. A blog network may also refer to a central website, such as WordPress, where a user creates an account and is then able to use their own blog. The created blog forms part of a network because it uses either a subdomain or a subfolder of the main domain, although in all other ways it can be entirely autonomous. This is also known as a hosted blog platform and usually uses the free WordPress Multisite software.
Its operating company Hangzhou Huandian Technology was administratively penalized and fined 10,000 yuan by local government. In August 2012, Bilibili started to display logos on its homepage to indicate affiliation with the state-owned Shanghai Media Group and share the use of various content provider licenses in hope to avoid future legal risk. Meanwhile, anonymous visitors to bilibili.tv got redirected to a subdomain of Shanghai Media Group Broad Band subsidiary (bilibili.smgbb.cn). Since November 2014, Chen Rui (陈睿), a billionaire tech magnate, has been CEO and Chairman of the Board of Bilibili. Chen earned his bachelor’s degree from Chengdu University of Information Technology.
Later that year, following 2004's Electronic Entertainment Expo (E3), Peter Rojas, the founder of and lead contributor to the company's flagship blog Engadget, formally introduced Joystiq to the masses, positioning the blog as an extension to Engadget's Gaming subdomain. However, being a separate and wholly video game-related entity, Joystiq allowed for much more in-depth analysis of the video game industry than the primarily consumer electronics-oriented Engadget. While Joystiq had featured content as early as April 2, the blog is not officially considered to have been launched until Rojas's public revelation on Engadget on Wednesday, June 16, 2004.
A specific function for SBDS in RNA metabolism or ribosome assembly or function is further supported by its localization to the nucleolus, the nuclear subdomain where these processes occur. In line with this, the yeast homologue, SdoI, has been shown to be critical for maturation of pre-60S ribosomes, by effecting release and recycling of the nucleolar shuttling factor Tif6. This is required for 60S maturation and translational activation of ribosomes. It has also been shown that the Dictyostelium discoideum homologue catalyzes the removal of eukaryotic initiation factor 6 (eIF6), which is required for the translational activation of ribosomes.
In certain domains you will find modification subdomains, such as the E subdomain seen in domains 1 and 4 in tyrocidine, which will generate the D-configured amino acid. On the final module is the TE domain used as a catalyst for cyclization or product release. The release of the product from the carrier protein is achieved through acylation of the active site serine of TE in which the decapeptide is transferred from the thiol ether to the serine residue. Deacylation can then occur through intramolecular cyclization or through hydrolysis to give the cyclic or linear product respectively (See figure 4).
Figure from original paper, showing line diagrams of phagosomes arising from omegasomes (part D). Omegasome is a cell compartment consisting of lipid bilayer membranes enriched for phosphatidylinositol 3-phosphate (abbreviated PI(3)P or PtdIns3P) and related to a process of autophagy. It is a subdomain of the endoplasmic reticulum (ER) membrane and has a morphology resembling Greek capital letter omega (Ω). Omegasomes are the sites from which phagophores form. Phagophores (also called "isolation membranes") are sack- like structures that mature into autophagosomes that fuse with lysosomes in order to degrade the contents of the autophagosomes.
Domain decomposition methods In mathematics, numerical analysis, and numerical partial differential equations, domain decomposition methods solve a boundary value problem by splitting it into smaller boundary value problems on subdomains and iterating to coordinate the solution between adjacent subdomains. A coarse problem with one or few unknowns per subdomain is used to further coordinate the solution between the subdomains globally. The problems on the subdomains are independent, which makes domain decomposition methods suitable for parallel computing. Domain decomposition methods are typically used as preconditioners for Krylov space iterative methods, such as the conjugate gradient method or GMRES.
The structure of the Salmonella typhimurium chemotaxis receptor methyltransferase CheR, bound to S-adenosylhomocysteine, has been determined to a resolution of 2.0 Angstrom. The structure reveals CheR to be a two-domain protein, with a smaller N-terminal helical domain linked via a single polypeptide connection to a larger C-terminal alpha/beta domain. The C-terminal domain has the characteristics of a nucleotide-binding fold, with an insertion of a small anti-parallel beta-sheet subdomain. The S-adenosylhomocysteine-binding site is formed mainly by the large domain, with contributions from residues within the N-terminal domain and the linker region.
Since the 2010s, advances in both machine learning algorithms and computer hardware have led to more efficient methods for training deep neural networks (a particular narrow subdomain of machine learning) that contain many layers of non-linear hidden units. By 2019, graphic processing units (GPUs), often with AI-specific enhancements, had displaced CPUs as the dominant method of training large-scale commercial cloud AI. OpenAI estimated the hardware compute used in the largest deep learning projects from AlexNet (2012) to AlphaZero (2017), and found a 300,000-fold increase in the amount of compute required, with a doubling-time trendline of 3.4 months.
The bifunctional aspartokinase-homoserine dehydrogenase (AK- HSD) enzyme has a regulatory domain that consists of two subdomains with a common loop-alpha helix-loop-beta strand loop-beta strand motif. Each subdomain contains an ACT domain that allows for complex regulation of several different protein functions. The AK-HSD gene codes for aspartate kinase, an intermediate domain (coding for the linker region between the two enzymes in the bifunctional form), and finally the coding sequence for homoserine dehydrogenase. As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and .
A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. The north of the Piashti valley has potential for use by moose (Alces alces), and traces of moose were found in the region in 1978 and 1979. Lake Salé has large beds of aquatic grass, and is frequented by several species of seabirds. A banding station for migratory birds operated at Lake Salé until 2004, and held the record for the highest concentration of green-winged teal (Anas carolinensis) in North America.
The specific gene that encodes RhoA, RHOA, is located on chromosome 3 and consists of four exons, which has also been linked as a possible risk factor for atherothrombolic stroke. Similar to other GTPases, RhoA presents a Rho insert in its primary sequence in the GTPase domain. RhoA contains also four insertion or deletion sites with an extra helical subdomain; these sites are characteristic of many GTPases in the Rho family. Most importantly, RhoA contains two switch regions, Switch I and Switch II, whose conformational states are modified following the activation or inactivation of the protein.
A map of the ecological regions of Quebec shows the river in sub-regions 6j-T and 6m-T of the east spruce/moss subdomain. The hoary bat (Lasiurus cinereus), suspected of being threatened or vulnerable in the province, was observed between 1999 and 2000 in a forest of firs and alders on the west side of the Loups Marins River. The Waterfowl concentration area of Rivière aux Loups Marins, Île de la Grande Anse, designated an IUCN Category IV Water fowl gathering area in 1998, covers the east part of the river's estuary and the coastline east to the Île de la Grande Anse.
The Matamec weather station, west of the river, records an annual average temperature of and average annual rainfall of . A climate model indicates that annual average temperature would be in the northern part of the watershed, while average annual rainfall would be about throughout the watershed. A map of the ecological regions of Quebec shows the Bouleau in sub- regions 6j-S, 6j-T and 6m-T of the east spruce/moss subdomain. Forest cover consists of black spruce (Picea mariana) and balsam fir (Abies balsamea), with black spruce dominant on the coastal plain and north of the watershed, and mixed spruce/fir in the central region.
PDB Code: 1DFM. Crystal Structure of BglII complexed with DNA at a resolution of 1.5Å Although restriction endonucleases show little sequence similarity, crystal structures reveal that they all share a highly similar α/β core consisting of a six-stranded β-sheet flanked by five α-helices, two of which mediate dimerization. This core carries the active site (catalytic center) and the residues that contact DNA in the major groove. BglII is unique in that its α/β core is augmented by a β-sandwich subdomain that has several projections that extend outward to grip the DNA, allowing BglII to completely encircle the DNA molecule.
In probability theory and statistical mechanics, the Gaussian free field (GFF) is a Gaussian random field, a central model of random surfaces (random height functions). gives a mathematical survey of the Gaussian free field. The discrete version can be defined on any graph, usually a lattice in d-dimensional Euclidean space. The continuum version is defined on Rd or on a bounded subdomain of Rd. It can be thought of as a natural generalization of one-dimensional Brownian motion to d time (but still one space) dimensions; in particular, the one-dimensional continuum GFF is just the standard one- dimensional Brownian motion or Brownian bridge on an interval.
While it is somewhat uncertain as to why this is, one group demonstrated that viral particle production in HPV chimeras was most efficient when the chimeric fusions were conducted directly downstream of the first transmembrane domain of NS2. This discovery implies that the first transmembrane segment of NS2’s hydrophobic amino-terminal subdomain physically interacts with upstream structural components of the HPV sequence. Its structure is indeed highly conserved between HCV genotypes, with a flexible helix in residues 3-11 and an alpha helix in residues 12-21. A subsequent implication is that the carboxy- terminal domain – which is also home to the proteasome region of NS2 – are not important in particle production.
Newsvine also has a social networking aspect, as each registered Newsvine user has user columns. These user columns can be used to manage and share their articles, seeds, online friends, recommendations, and other statistical information. Every user has a user column, and each is given their own subdomain to access it (.newsvine.com). User columns are customizable: aspects of the layouts can be moved or hidden, a user photo and biography can be added, a header (such as a welcome message) can be added, friends can be invited to Newsvine or added to the user's friends list, recommendations (such as favorite books, bands, blogs, etc.) can be shown, and comments and feedback from other users can be managed.
According to one model, G6P acts as an allosteric inhibitor which binds the N-terminal domain to stabilize its closed conformation, which then stabilizes a conformation of the C-terminal flexible subdomain that blocks ATP. A second model posits that G6P acts as an active inhibitor that stabilizes the closed conformation and competes with ATP for the C-terminal binding site. Results from several studies suggest that the C-terminal is capable of both catalytic and regulatory action. Meanwhile, the hydrophobic N-terminal lacks enzymatic activity by itself but contains the G6P regulatory site and the PBD, which is responsible for the protein’s stability and binding to the outer mitochondrial membrane (OMM).
The dual counterpart to BDD is FETI, which enforces the equality of the solution between the subdomain by Lagrange multipliers. The base versions of BDD and FETI are not mathematically equivalent, though a special version of FETI designed to be robust for hard problems M. Bhardwaj, D. Day, C. Farhat, M. Lesoinne, K. Pierson, and D. Rixen, Application of the FETI method to ASCI problems – scalability results on 1000 processors and discussion of highly heterogeneous problems, International Journal for Numerical Methods in Engineering, 47 (2000), pp. 513-535\. has the same eigenvalues and thus essentially the same performance as BDD.Y. Fragakis, Force and displacement duality in Domain Decomposition Methods for Solid and Structural Mechanics.
Some are formed with units of the same chain, between the "barbed" end on one monomer and the "pointed" end of the next one. While the monomers in adjacent chains make lateral contact through projections from subdomain IV, with the most important projections being those formed by the C-terminus and the hydrophobic link formed by three bodies involving residues 39–42, 201–203, and 286. This model suggests that a filament is formed by monomers in a "sheet" formation, in which the subdomains turn about themselves, this form is also found in the bacterial actin homologue MreB. The F-actin polymer is considered to have structural polarity due to the fact that all the microfilament's subunits point towards the same end.
Located about 70 km north of Quebec, Lac-des-Neiges has an ancient forest spread over three sites: on the west shore of Lac des Neiges (facing the mouth of the lake), on the north shore of the dam of head of the rivière des Neiges and on the west bank of the Rivière des Neiges below Lac English. Covering , this ancient forest is found in the bioclimatic subdomain of the eastern white birch fir forest. The last great ice age, which would have ended about 10,000 years ago, left significant glacial deposits in this area; these deposition layers generally have a thickness of . The main feature of this ancient forest is the black spruce fir tree, some trees of which are 200 years old.
In domain decomposition methods, the construction of a coarse problem follows the same principles as in multigrid methods, but the coarser problem has much fewer unknowns, generally only one or just a few unknowns per subdomain or substructure, and the coarse space can be of a quite different type that the original finite element space, e.g. piecewise constants with averaging in balancing domain decomposition or built from energy minimal functions in BDDC. The construction of the coarse problem in FETI is unusual in that it is not obtained as a Galerkin approximation of the original problem, however. In Algebraic Multigrid Methods and in iterative aggregation methods in mathematical economics and Markov chains, the coarse problem is generally obtained by the Galerkin approximation on a subspace.
Lebkowsky joined the WELL in 1990, and became a host or co-host of several forums on the conferencing system, including forums devoted to Factsheet Five, where he had a brief stint as book review editor, and Mondo 2000, where he wrote several articles and formed friendships with editors RU Sirius and Jude Milhon. Through the WELL, he also became associated with Howard Rheingold and Whole Earth Review, the Electronic Frontier Foundation, and boing boing, where he was Associate Editor. He had early associations with staff at Wired Magazine and conducted a regular, weekly series of chats called Electronic Frontiers Forum at HotWired. He was a subdomain editor for the Millennium Whole Earth Catalog and, in 1996, became a community host at Howard Rheingold's Electric Minds.
The PAH monomer (51.9 kDa) consists of three distinct domains: a regulatory N-terminal domain (residues 1–117) that contains a Phe-binding ACT subdomain, the catalytic domain (residues 118–427), and a C-terminal domain (residues 428–453) responsible for oligomerization of identical monomers. Extensive crystallographic analysis has been performed, especially on the pterin- and iron-coordinated catalytic domain to examine the active site. The structure of the N-terminal regulatory domain has also been determined, and together with the solved structure of the homologous tyrosine hydroxylase C-terminal tetramerization domain, a structural model of tetrameric PAH was proposed. Using X-ray crystallography, the structure of full-length rat PAH was determined experimentally and showed the auto- inhibited, or resting-state form of the enzyme.
Actin networks are distributed throughout the cytoplasm of cells that have been cultivated in vitro. There is a concentration of the network around the nucleus that is connected via spokes to the cellular cortex, this network is highly dynamic, with a continuous polymerization and depolymerization. Structure of the C-terminal subdomain of villin, a protein capable of splitting microfilamentsPDB ; Even though the majority of plant cells have a cell wall that defines their morphology and impedes their movement, their microfilaments can generate sufficient force to achieve a number of cellular activities, such as, the cytoplasmic currents generated by the microfilaments and myosin. Actin is also involved in the movement of organelles and in cellular morphogenesis, which involve cell division as well as the elongation and differentiation of the cell.
Structure of the NBD of ABC transporters with bound nucleotide (). Linear representation of protein sequence above shows the relative positions of the conserved amino acid motifs in the structure (colors match with 3D structure) The ABC domain consists of two domains, the catalytic core domain similar to RecA-like motor ATPases and a smaller, structurally diverse α-helical subdomain that is unique to ABC transporters. The larger domain typically consists of two β-sheets and six α helices, where the catalytic Walker A motif (GXXGXGKS/T where X is any amino acid) or P-loop and Walker B motif (ΦΦΦΦD, of which Φ is a hydrophobic residue) is situated. The helical domain consists of three or four helices and the ABC signature motif, also known as LSGGQ motif, linker peptide or C motif.
The kinase (CR3) domain of human Raf kinases is inhibited by two mechanisms: autoinhibition by its own regulatory Ras-GTP-binding CR1 domain and a lack of post-translational phosphorylation of key serine and tyrosine residues (S338 and Y341 for c-Raf) in the CR2 hinge region. During B-Raf activation, the protein's autoinhibitory CR1 domain first binds Ras-GTP's effector domain to the CR1 Ras-binding domain (RBD) to release the kinase CR3 domain like other members of the human Raf kinase family. The CR1-Ras interaction is later strengthened through the binding of the cysteine-rich subdomain (CRD) of CR1 to Ras and membrane phospholipids. Unlike A-Raf and C-Raf, which must be phosphorylated on hydroxyl-containing CR2 residues before fully releasing CR1 to become active, B-Raf is constituitively phosphorylated on CR2 S445.
Gary Marchionini is a leader in defining theory of human information interaction and exploratory search and his work sits at the intersection of human-computer interaction and information retrieval, a subdomain known as human-computer information interaction (HCIR). His 1995 book, Information Seeking in Electronic Environments has been influential in shaping our understanding of search as a learning activity that is dependent not only on individual search capabilities and preferences but on the nature of the topical domain, the search task, and the features of the search system. A pioneer in the development of digital libraries, he led the development of one of the early digital video repositories, the Open Video Project and chaired the 2008 ACM/IEEE Joint Conference on Digital Libraries Conference and was program chair for the 2006 conference. His research has been supported by the U.S. National Science Foundation and several other foundations and corporate research laboratories.
The position of the primary pore is indicated by arrowheads. Adapted from The structure of one of the two tandem DUF1608 repeats that comprise the major MSTP of M. acetivorans (MA0829) has been determined at high resolution by X-ray crystallography. The structure of the C-terminal DUF1608 tandem repeat (CTR) of MA0829 revealed that the DUF1608 protein domain is composed of two structurally similar β-sandwich domains connected by a short connector subdomain. The β-sandwich domains are structurally similar not only to each other but also to other proteins associated with envelope structures of disparate species including bacterial, fungal, and viral entities. While the structure of only one of the two DUF1608 domains of the MA0829 protein was determined the structure of the full-length MA0829 tandem DUF1608 repeat protein (minus the N-terminal signal peptide and C-terminal tether and anchor) could be modeled by virtue of the MA0829 CTR forming the same crystallographic dimer in two different crystal forms.
The original problem considered by Schwarz was a Dirichlet problem (with the Laplace's equation) on a domain consisting of a circle and a partially overlapping square. To solve the Dirichlet problem on one of the two subdomains (the square or the circle), the value of the solution must be known on the border: since a part of the border is contained in the other subdomain, the Dirichlet problem must be solved jointly on the two subdomains. An iterative algorithm is introduced: # Make a first guess of the solution on the circle's boundary part that is contained in the square # Solve the Dirichlet problem on the circle # Use the solution in (2) to approximate the solution on the square's boundary # Solve the Dirichlet problem on the square # Use the solution in (4) to approximate the solution on the circle's boundary, then go to step (2). At convergence, the solution on the overlap is the same when computed on the square or on the circle.
The next major change to adaptive standard web design came in more recent years, particularly with the rise of the iPhone and two years later widespread 3G availability dramatically increasing connection speeds and available bandwidth, a two design dynamic system became the most utilized, a mobile layout (usually with the subdomain prefix "m") optimized for iPhone and a desktop layout. The mobile versions were still usually "scaled-down" with lower quality images and sometimes content such as videos removed to decrease loading time. This was also the first time web developers had to design with a touch screen in mind, using larger clickable links and buttons to facilitate the use of fingers as pointers. As Google's Android OS rose to popularity and introduced more variation in the market share of smartphones, along with the widespread implementation of 4G LTE's ultra fast mobile broadband, it was no longer necessary to downgrade mobile media quality or trim content to deal with slow connection speeds, and, with so much variation in devices, the multi-page paradigm of Standard Dynamic web design widely lost favor with developers.

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