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139 Sentences With "spontaneous abortion"

How to use spontaneous abortion in a sentence? Find typical usage patterns (collocations)/phrases/context for "spontaneous abortion" and check conjugation/comparative form for "spontaneous abortion". Mastering all the usages of "spontaneous abortion" from sentence examples published by news publications.

Instances of spontaneous abortion within the first six weeks of pregnancy were not included, the authors write, because many cases of spontaneous abortion during the first weeks of gestation may go unrecognized.
Lead exposure can cause spontaneous abortion, low birth weight and reduced growth in children.
Also called "bovine anemia," the illness causes lethargy, lack of appetite and, in pregnant cows, spontaneous abortion or stillbirth.
A miscarriage, or "spontaneous abortion," is usually defined as the loss of a pregnancy before the 20th week of gestation.
SARS-associated illnesses were linked to cases of spontaneous abortion, maternal death and critical maternal illness, a 2004 study found.
Cervical infections caused by listeriosis in pregnant women may result in spontaneous abortion during the second or third trimesters or stillbirth.
Though I knew that "spontaneous abortion" was a medical term, it shook me to see the word "abortion" associated with my much-wanted baby.
The analysis also showed no elevated risk for spontaneous abortion, preterm birth, low birthweight, stillbirth or having a child who is small for gestational age.
But for Rai's followers, he wraps up his lecture with this message: these modern contraception methods can cause a woman to have a spontaneous abortion.
Medically, a healthcare provider cannot tell the difference between someone having a spontaneous abortion (commonly known as a miscarriage) or one induced by medication abortion pills.
Additionally, researchers noted that "women with spontaneous abortion were more likely to be older, to be living alone, and to have comorbidities and infections," the study states.
That study found an increased risk for spontaneous abortion, or miscarriage, in the 229 days after a pregnant woman is vaccinated, but only in a very specific scenario.
In the cases of azithromycin and clarithromycin (both macrolides), the risk of spontaneous abortion increased by 65 percent and twofold, respectively, which was consistent with findings in previous studies.
And while the current president, Nayib Bukele, has said that women living in poverty should not be presumed guilty after having a "spontaneous abortion," he has not spoken about Hernández's case.
After adjusting for a number of factors, the study found that the "use of macrolides (excluding erythromycin), quinolones, tetracyclines, sulfonamides and metronidazole during early pregnancy was associated with an increased risk of spontaneous abortion," the study states.
He said that most of the time, the pathologist would not be able to determine a cause for the miscarriage, but that any information that was gathered might become part of the body of research on spontaneous abortion.
"By 1940, it was also recognized that an initial rise in these hormones followed by a premature fall was associated with spontaneous abortion," Greene wrote in an editorial published alongside the new study in the New England Journal of Medicine.
"Sexually transmitted and reproductive tract infections are linked to devastating birth consequences for pregnant women, including spontaneous abortion, stillbirth and premature and low birthweight," said Matthew Chico, lead author of the report, which studied more than 1,000 pregnant women in rural Zambia.
But in June of 1996, when I was entering the second week of my second trimester, I had a miscarriage — in medical terms, a spontaneous abortion — while preparing to deliver a paper at a prestigious women's history conference a thousand miles from home.
Her body, then, collapses, suggesting the death of her child due to a spontaneous abortion.
The most common cause of spontaneous abortion during the first trimester is chromosomal abnormalities of the embryo or fetus, accounting for at least 50% of sampled early pregnancy losses. Other causes include vascular disease (such as lupus), diabetes, other hormonal problems, infection, and abnormalities of the uterus. Advancing maternal age and a woman's history of previous spontaneous abortions are the two leading factors associated with a greater risk of spontaneous abortion. A spontaneous abortion can also be caused by accidental trauma; intentional trauma or stress to cause miscarriage is considered induced abortion or feticide.
To date, rigorous studies evaluating whether treatment with antidepressants during pregnancy increases the risk of spontaneous abortion have been relatively sparse.
Depression during pregnancy is associated with an increased risk of spontaneous abortion. In a review by Frazier et al., acute and chronic stress during pregnancy can diminish proper immunological activity crucial during pregnancy, and can possibly induce spontaneous abortion. There is still a debate on whether the miscarriage is due to the depressive disease state or the anti-depressant medication.
Systemic lupus erythematosus and pregnancy confers an increased rate of fetal death in utero and spontaneous abortion (miscarriage), as well as of neonatal lupus.
A 2015 systematic review and meta-analysis of prospective studies found insufficient evidence to support an association between induced or spontaneous abortion and an increased risk of breast cancer.
Endometrial or placental development issues may also cause a pregnancy to fail. Additionally, the frequency of spontaneous abortion increases with the mother's age. Older mothers have a higher rate of genetic abnormalities that can trigger pregnancy loss. Because human pregnancy is so costly, and human offspring so dependent on their mothers, early spontaneous abortion is high to ensure that energy of a pregnancy is spent on developing a fetus with a high chance of survival.
In humans, chromosomal abnormalities arising from incorrect spermatogenesis results in congenital defects and abnormal birth defects (Down syndrome, Klinefelter syndrome) and in most cases, spontaneous abortion of the developing foetus.
The medical terminology applied to experiences during early pregnancy has changed over time. Before the 1980s, health professionals used the phrase spontaneous abortion for a miscarriage and induced abortion for a termination of the pregnancy. In the late 1980s and 1990s, doctors became more conscious of their language in relation to early pregnancy loss. Some medical authors advocated change to use of miscarriage instead of spontaneous abortion because they argued this would be more respectful and help ease a distressing experience.
The initial evaluation of early pregnancy bleeding involves a history and physical examination. The relevant history includes determining the gestational age of fetus and characterizing the bleeding. Bleeding that is at least as heavy as menstrual bleeding or associated with clots, tissue, lightheadedness, or pelvic discomfort is associated with increased risks of ectopic pregnancy and spontaneous abortion. Discomfort in the middle of the abdomen is more closely associated with spontaneous abortion; discomfort on a side of the abdomen is more closely associated with ectopic pregnancy.
Abortion is the ending of a pregnancy by removal or expulsion of an embryo or fetus before it can survive outside the uterus. An abortion that occurs without intervention is known as a miscarriage or spontaneous abortion.
In 1997, Wingo et al. reviewed 32 studies on the abortion-breast cancer relationship and concluded that the results of studies on this subject were too inconsistent to allow for definitive conclusions, for either induced or spontaneous abortions. A 2004 analysis of data from 53 studies involving 83,000 women with breast cancer reported no increased risk among women who had had either an induced or spontaneous abortion. The relative risk of breast cancer for women who had a spontaneous abortion in this analysis was 0.98, and that for induced abortion was 0.93.
However, historical evidence suggests a potential increase in risk of spontaneous abortion amongst pregnant female dental professionals, with the risk increasing with greater contact time with nitrous oxide sedation treatment and the absence of scavenging equipment to remove any leaking gas. Dental amalgam is a mercury-containing filling material used to fill cavities once tooth decay has been removed. The use of dental fillings containing mercury is to be phased down in accordance with the Minamata Convention, however its use remains widespread. Weak relationships exist between mercury and spontaneous abortion, congenital abnormalities and reduced fertility.
Ayhan Ulubelen (born 1931) is an analytical chemist and member of the Turkish Academy of Sciences. She has contributed to the isolation and testing of natural products from Turkish plants relevant to spontaneous abortion, cancer, HIV, and diabetes.
The fetus inside a pregnant woman may be viewed as an unusually successful allograft, since it genetically differs from the woman. In the same way, many cases of spontaneous abortion may be described in the same way as maternal transplant rejection.
The most common side effects include insomnia (difficulty sleeping), headache, nausea (feeling sick), anxiety, irritability, dizziness, depression, tremor, sleep disorders, tiredness, vomiting, vertigo (a spinning sensation) and dyspepsia (heartburn). Serious but rare side effects are abnormal loss of weight and spontaneous abortion.
Mycoplasma species have been isolated from women with bacterial vaginosis. M. genitalium is found in women with pelvic inflammatory disease. In addition, infection is associated with increased risk of cervicitis, infertility, preterm birth and spontaneous abortion. Mycoplasma genitalium has developed resistance to some antibiotics.
Usage of aspirin during pregnancy is not recommended. Aspirin use during pregnancy has not demonstrated an increased risk of spontaneous abortion within the early weeks of pregnancy. However, its usage during organogenesis and the third trimester can lead to elevated risk of intrauterine growth retardation and maternal hemorrhage.
No clinical studies evaluating the risk for fetuses are available. A study using large doses of tocilizumab in pregnant animals has found an increased likelihood for spontaneous abortion. It is not known whether the drug is secreted into the breast milk, nor if this would pose a risk for the nursling.
Up to 40% of cows may have a spontaneous abortion. Younger animals usually develop more severe disease. About 80% of dogs can survive with treatment, but the survival rate is reduced if the lungs are involved. ELISA and microscopic agglutination tests are most commonly used to diagnose leptospirosis in animals.
Risk factors for ectopic pregnancy or spontaneous abortion should also be considered. The physical examination includes assessing vital signs and performing an abdominal and pelvic examination. Signs of hemodynamic instability or peritonitis require emergent intervention. A pelvic examination may reveal non-obstetric causes of bleeding such as bleeding from the vagina or cervix.
This can result in spontaneous abortion or major developmental disorders. For many infections, the baby is more at risk at particular stages of pregnancy. Problems related to perinatal infection are not always directly noticeable. The term TORCH complex refers to a set of several different infections that may be caused by transplacental infection.
Chronic exposure leads to common forms of respiratory failure (emphysema, pulmonary fibrosis) and focused hepatotoxicity (hepatomegaly, hepatic fibrosis). Continuous exposure can cause CNS depression including euphoria and disorientation. Decreased male libido, spontaneous abortion, and birth defects are known major reproductive defects associated with vinyl chloride. Vinyl chloride can have acute dermal and ocular effects.
Diabetic embryopathy may result in early or late spontaneous abortion and stillbirth. In maternal diabetes, 90% of pregnancy losses happen in the first trimester due to oxidative stress. Diabetic embryopathy abortions in the second- trimester are most likely due to severe birth defect, maternal metabolic derangement, placental insufficiency and fetal hypoxia due to membrane rupture.
Neospora caninum is a coccidian parasite that was identified as a species in 1988. Prior to this, it was misclassified as Toxoplasma gondii due to structural similarities. The genome sequence of Neospora caninum has been determined by the Wellcome Trust Sanger Institute and the University of Liverpool. Neospora caninum is an important cause of spontaneous abortion in infected livestock.
As many as half of all infants born to mothers with chlamydia will be born with the disease. Chlamydia can affect infants by causing spontaneous abortion; premature birth; conjunctivitis, which may lead to blindness; and pneumonia. Conjunctivitis due to chlamydia typically occurs one week after birth (compared with chemical causes (within hours) or gonorrhea (2–5 days)).
Miscarriage occurs in all animals that experience pregnancy, though in such contexts it is more commonly referred to as a "spontaneous abortion" (the two terms are synonymous). There are a variety of known risk factors in non-human animals. For example, in sheep, miscarriage may be caused by crowding through doors, or being chased by dogs.Spencer, James.
Sheep Husbandry in Canada , page 124 (1911). In cows, spontaneous abortion may be caused by contagious disease, such as brucellosis or Campylobacter, but often can be controlled by vaccination."Beef cattle and Beef production: Management and Husbandry of Beef Cattle" , Encyclopaedia of New Zealand (1966). In many species of sharks and rays, stress induced miscarriage occurs frequently on capture.
The narratives of women tend to coincide with quantified and measurable effects. In women who are induced to have an abortion, an identical grieving process can occur. The emotional responses to a spontaneous abortion (miscarriage) and an elective abortion are sometimes identical. Spanish women experience grief in much the same way in the rest of Western culture.
The virus causing EVA was first identified following an outbreak of respiratory disease and spontaneous abortion on a horse farm in Ohio in 1953. The first outbreak of EVA in the UK was in 1993. The outbreak affected six premises and around 100 horses were infected. Further spread of the virus was prevented by movement restrictions.
Spontaneous abortion occurs in various animals. For example, in sheep it may be caused by stress or physical exertion, such as crowding through doors or being chased by dogs. In cows, abortion may be caused by contagious disease, such as brucellosis or Campylobacter, but can often be controlled by vaccination. Eating pine needles can also induce abortions in cows.
Recet studies indicate that the products of conception may be susceptible to pathogenic infections, including viral infections. Indeed, footprints of JC polyomavirus and Merkel cell polyomavirus have been detected in chorionic villi from females affected by spontaneous abortion as well as pregnant women. Another virus, BK polyomavirus has been detected in the same tissues, but with lesser extent.
Warfarin is a teratogen which can cross from the mother to the developing fetus. The inhibition of clotting factors can lead to internal bleeding of the fetus while the inhibition of osteocalcin causes lower bone growth. As well as birth defects, warfarin can induce spontaneous abortion or stillbirth.Hou, J. 2004, "Fetal warfarin syndrome", Chang Gung medical journal, vol.
Immune tolerance in pregnancy or maternal immune tolerance is the immune tolerance shown towards the fetus and placenta during pregnancy. This tolerance counters the immune response that would normally result in the rejection of something foreign in the body, as can happen in cases of spontaneous abortion. It is studied within the field of reproductive immunology.
This can result in spontaneous abortion or major developmental disorders. For many infections, the baby is more at risk at particular stages of pregnancy. Problems related to perinatal infection are not always directly noticeable. Apart from infecting the fetus, transplacental pathogens may cause placentitis (inflammation of the placenta) and/or chorioamnionitis (inflammation of the fetal membranes).
Recent studies indicate that PBMCs may be susceptible to pathogenic infections, such as Ureaplasma parvum and urealiticum, Mycoplasma genitalium and hominis and Chlamydia trachomatis infections. PBMCs may be also susceptible to viral infections. Indeed, footprints of JC polyomavirus and Merkel cell polyomavirus have been detected in PBMCs from females affected by spontaneous abortion as well as pregnant women.
Sonia married three times and they were of a short duration. One of her spouses was the producer Óscar Rodríguez. None of her marriages produced children (she was pregnant fourteen times) as she suffered from spontaneous abortion. She decided to adopt two children: Camilo José Tomás and Javiera Esperanza on whom she poured all the attention she could give.
One historical cell line used in rubella vaccines was obtained from a fetus aborted due to infection with rubella. Rubella during pregnancy can lead to miscarriage (spontaneous abortion), and if it does not, there is a risk of severe disability due to congenital rubella syndrome. By one estimate, rubella vaccination may prevent up to 5,000 miscarriages per year in the United States.
The frequency of infection in preterm birth is inversely related to the gestational age. Mycoplasma genitalium infection is associated with increased risk of preterm birth, and spontaneous abortion. Infectious microorganisms can be ascending, hematogeneous, iatrogenic by a procedure, or retrograde through the Fallopian tubes. From the deciduas they may reach the space between the amnion and chorion, the amniotic fluid, and the fetus.
Generally, patients who are not treated will experience one to four episodes of fever before illness resolves. TBRF contracted during pregnancy can cause spontaneous abortion, premature birth, and neonatal death. The maternal-fetal transmission of Borrelia is believed to occur either transplacentally or while traversing the birth canal. In general, pregnant women have higher spirochaete loads and more severe symptoms than nonpregnant women.
Locations can include the subcutaneous tissue on the scalp, the pleura (pleural effusion), the pericardium (pericardial effusion) and the abdomen (ascites). Edema is usually seen in the fetal subcutaneous tissue, sometimes leading to spontaneous abortion. It is a prenatal form of heart failure, in which the heart is unable to satisfy demand (in most cases abnormally high) for blood flow.
Trichomonas foetus causes spontaneous abortion in cattle, Dientamoeba fragilis causes diarrhea in humans, and Trichomonas vaginalis is a sexually transmitted disease. Image of a cultured Tritrichomonas foetus Trichomonas foetus is a parasite that resides in the urogenital tract of cattle and causes bovine trichomoniasis. Trichomoniasis is a sexually transmitted disease that causes infertility in heifers. Most infertility is caused by sudden embryonic death.
While most pregnancies have positive outcomes there is a greater risk of adverse events occurring during pregnancy. SLE causes an increased rate of fetal death in utero and spontaneous abortion (miscarriage). The overall live-birth rate in people with SLE has been estimated to be 72%. Pregnancy outcome appears to be worse in people with SLE whose disease flares up during pregnancy.
A hydatidiform mole is a pregnancy/conceptus in which the placenta contains grapelike vesicles (small sacs) that are usually visible to the naked eye. The vesicles arise by distention of the chorionic villi by fluid. When inspected under the microscope, hyperplasia of the trophoblastic tissue is noted. If left untreated, a hydatidiform mole will almost always end as a spontaneous abortion (miscarriage).
These viruses generally infect the gastrointestinal and respiratory tracts. Some may cross the placenta and cause congenital infection of the fetus. Canine minute virus, first isolated in 1967 and associated with disease in 1970, causes respiratory disease with breathing difficulty and enteritis with severe diarrhoea, spontaneous abortion of fetuses, and death of newborn puppies. Human bocaviruses were first isolated in 2005 in Sweden.
In April 1912, Helene married Felix Deutsch. Following the outbreak of World War I, Helene experienced the first of many miscarriages.Appignanesi/Forrester, p. 315 In The Psychology of Women, Helene discussed the concept of spontaneous abortion and miscarriage as a result of psychological factors, with a critical factor involving the 'pregnant woman's unconscious rejection of an identification with her own mother.
Mortality is often thought to be due to subsequent infections due to the weakened immune symptoms and opportunistic pathogen invasion, or consequences of malnutrition due to weight loss in children. In a study focusing on pediatric and gestational effects of the disease, mortality rates for pregnant women with the acute phase were estimated at 40% and rates of spontaneous abortion in another 40%.
However, fescue poisoning, caused by ergot alkaloids produced by the endophytic fungus Epichloë coenophiala, is a risk for pregnant mares. During the last three months of pregnancy fescue poisoning increases the risk of spontaneous abortion, stillbirths, retained placenta, absent milk production, and prolonged pregnancy. Incorporating legumes into the fescue can be a way to increase livestock gains and conception rates, even if the fescue is infected.Fescue Toxicosis.
Lymphocytic choriomeningitis is a particular concern in obstetrics, as vertical transmission is known to occur. For immunocompetent mothers, there is no significant threat, but the virus has damaging effects upon the fetus. If infection occurs during the first trimester, LCMV results in an increased risk of spontaneous abortion. Later congenital infection may lead to malformations such as intracranial calcifications, hydrocephalus, microcephaly or macrocephaly, intellectual disabilities, and seizures.
The researchers involved in human reproductive ecology use the combined approach of demography and evolutionary biology to explain the reproductive phenomenon. Biodemography is the study of demography related to biology and evolutionary biology. Biodemographers do research on demographic outcomes such as conception, spontaneous abortion, births, marriage, divorce, menarche, menopause, aging, and mortality. Biodemographers use mathematical models, statistical estimates and biomarkers to analyze the demographic data.
Viral infection can cause abortion in dogs. Cats can experience spontaneous abortion for many reasons, including hormonal imbalance. A combined abortion and spaying is performed on pregnant cats, especially in trap–neuter–return programs, to prevent unwanted kittens from being born. Female rodents may terminate a pregnancy when exposed to the smell of a male not responsible for the pregnancy, known as the Bruce effect.
They can cause wide deaths in populations of chinchillas and spontaneous abortion in pregnant chinchillas. Respiratory tract infections can be caused by many pathogens, but, regardless of cause, usually result in difficult breathing and a nasal discharge. Young chinchilla are more likely to be affected and these infections are unlikely to result in an epidemic, even if transmissible. Gastrointestinal disorders are observed as either constipation or diarrhea.
C. fetus has been discovered to cause some cases of spontaneous abortion in cattle and sheep and has become an important bacterial species in the livestock industry. C. fetus is also an opportunistic human pathogen and can cause bacteremia and thrombophlebitis. Though rare, C. fetus can lead to fatal sepsis in newborns and immunocompromised individuals. C. fetus, along with C. coli, has been shown to cause sepsis.
Congenital disease occurs due to the acquisition of the organism by a pregnant woman exposed to tissue cysts or oocytes in uncooked meat or substances contaminated with cat feces. Spontaneous abortion may result if the disease is acquired during the first trimester. Congenital toxoplasmosis may lead to hydrocephalus, seizures, lymphadenopathy, hepatosplenomegaly, rash, and fever. However, retinochoroiditis is the most common manifestation, occurring in 3/4 of cases.
However, the measured incidence is between 1/10,000 to 1/60,000 (it differs depending on heritage and descent). This is much lower than expected. This indicates that many cases of SLOS are undetected, and is likely due to either spontaneous abortion caused by severe mutations (miscarriage), or mild cases that are undiagnosed. Females lack the characteristic genital malformations that affected males have, and thus are less likely to be correctly diagnosed.
Miscarriage, also known in medical terms as a spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently. Some use the cutoff of 20 weeks of gestation, after which fetal death is known as a stillbirth. The most common symptom of a miscarriage is vaginal bleeding with or without pain. Sadness, anxiety and guilt may occur afterwards.
St. Fulgentius opposed abortion even for the purpose of saving the woman's life, saying: "But let the child be brought to term and baptized and saved from perdition."ented a baptismal syringe, wherewith to baptize a fetus in utero in the event of a spontaneous abortion, a miscarriage. [ftn. 10: St. Fulgentius, De Fide 27, cited by E. Westermarck, The Origin and Development of the Moral Ideas (1908), vol. I, pp.
Abortion is the ending of a pregnancy by removal or expulsion of an embryo or fetus. An abortion that occurs without intervention is known as a miscarriage or "spontaneous abortion" and occurs in approximately 30% to 50% of pregnancies. When deliberate steps are taken to end a pregnancy, it is called an induced abortion, or less frequently "induced miscarriage". The unmodified word abortion generally refers to an induced abortion.
Retained products of conception is where products of conception remain in the uterus after childbirth, medical abortion or miscarriage (also known as spontaneous abortion).Definition: 'Retained Products Of Conception' from MediLexicon. Retrieved Feb 2014. Miscarriage with retained products of conception is termed delayed when no or very little products of conception have been passed, and incomplete when some products have been passed but some still remain in utero.
Miscarriage, also known as spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently. Some use the cutoff of 20 weeks of gestation, after which fetal death is known as a stillbirth. The death of the fetus or neonate at the end of the pregnancy, during labour and delivery, or just after birth is counted as perinatal mortality.
The BK virus rarely causes disease but is typically associated with patients who have had a kidney transplant; many people who are infected with this virus are asymptomatic. If symptoms do appear, they tend to be mild: respiratory infection or fever. These are known as primary BK infections. Although without any clinical symptoms, footprints of BK virus have been detected in specimens from females affected by spontaneous abortion.
Clinically, Breus' mole may be asymptomatic, or may present with signs of decreased blood flow to the foetus such as growth restriction and foetal distress. Postnatally, Breus' mole is found in placental examination following live birth or spontaneous abortion. Breus' mole is diagnosed antenatally by ultrasound, where a thick multilobulated hematoma can be seen beneath the chorion. Occasionally, subchorial thrombohematoma may later become intraplacental, making its diagnosis difficult.
Recent studies indicate that the Chorion may be susceptible to pathogenic infections, including viral infections. Recents findings indicate that ureaplasma parvum can infect the Chorion tissue, thereby impacting pregnancy outcome. In addition, footprints of JC polyomavirus and Merkel cell polyomavirus have been detected in chorionic villi from females affected by spontaneous abortion as well as pregnant women. Another virus, BK polyomavirus has been detected in the same tissues, but with lesser extent.
Antidepressant exposure (including citalopram) during pregnancy is associated with shorter duration of gestation (by three days), increased risk of preterm delivery (by 55%), lower birth weight (by 75 g), and lower Apgar scores (by <0.4 points). Antidepressant exposure is not associated with an increased risk of spontaneous abortion. It is uncertain whether there is an increased prevalence of septal heart defects among children whose mothers were prescribed an SSRI in early pregnancy.
Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L. ivanovii and L. grayi have been reported in certain cases. Listeriosis can cause severe illness, including severe sepsis, meningitis, or encephalitis, sometimes resulting in lifelong harm and even death. Those at risk of severe illness are the elderly, fetuses, newborns and those who are immunocompromised. In pregnant women it may cause stillbirth or spontaneous abortion, and preterm birth is common.
There is a consistent association of M. genitalium infection and female reproductive tract syndromes. M. genitalium infection was significantly associated with increased risk of preterm birth, spontaneous abortion, cervicitis, and pelvic inflammatory disease. In addition, this pathogen may latently infect the chorionic villi tissues of pregnant women, thereby impacting pregnancy outcome. Infertility risk is also strongly associated with infection with M. genitalium, although evidence suggests it is not associated with male infertility.
Veterinary Medicine, A textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses. Harcourt Publishers Limited, London, pp. 867–882. . The most common clinical signs of cattle infected with B. abortus are high incidences of abortions, arthritic joints, and retained placenta. The two main causes for spontaneous abortion in animals are erythritol, which can promote infections in the fetus and placenta, and the lack of anti-Brucella activity in the amniotic fluid.
A second route of transmission is the congenital transmission from mother to offspring. Transplacental transmission (passage from mother to offspring during pregnancy) has also been shown to occur in dogs, cats, sheep and cattle. If the intermediate host acquires the disease during pregnancy, it activates these cysts, and active infection often causes spontaneous abortion. In addition, if the aborted fetus and membranes are then eaten by the definitive host, they cause further infection and the cycle is complete.
Other diseases are also known to make animals susceptible to miscarriage. Spontaneous abortion occurs in pregnant prairie voles when their mate is removed and they are exposed to a new male, an example of the Bruce effect, although this effect is seen less in wild populations than in the laboratory. Female mice who had spontaneous abortions showed a sharp rise in the amount of time spent with unfamiliar males preceding the abortion than those who did not.
Appendectomy was successful but premature labor occurred 7 days after discharge, leading to spontaneous abortion. ;RLP and inguinal hernia Several cases of varicosity, of the round ligament during pregnancy leading to RLP have been reported although they were frequently misdiagnosed as inguinal hernia. In one case, a woman in the 28th week of gestation developed a lump in the left pubic area. The swelling was prominent when standing but not in the supine position and has a cough impulse.
Lynn Thorndike, A History of Magic and Experimental Science, p. 334. Alvaro Alonso Barba's work on metallurgy (Madrid, 1640) touts the efficacy of the aetites, advising that the stone be tied to the left arm to prevent spontaneous abortion, and to the right arm for the opposite effect. The work was widely reviewed, reprinted and translated.Full title Arte de los metales en que se enseña el verdadero beneficio de los de oro y plata por açogue.
Miscarriage, also known as spontaneous abortion, is the unintentional expulsion of an embryo or fetus before the 24th week of gestation. A pregnancy that ends before 37 weeks of gestation resulting in a live-born infant is a "premature birth" or a "preterm birth". When a fetus dies in utero after viability, or during delivery, it is usually termed "stillborn". Premature births and stillbirths are generally not considered to be miscarriages although usage of these terms can sometimes overlap.
Antidepressant exposure (including escitalopram) is associated with shorter duration of pregnancy (by three days), increased risk of preterm delivery (by 55%), lower birth weight (by 75 g), and lower Apgar scores (by <0.4 points). Antidepressant exposure is not associated with an increased risk of spontaneous abortion. There is a tentative association of SSRI use during pregnancy with heart problems in the baby. The advantages of their use during pregnancy may thus outweigh the possible negative effects on the baby.
Family planning is among the most cost- effective of all health interventions. Costs of contraceptives include method costs (including supplies, office visits, training), cost of method failure (ectopic pregnancy, spontaneous abortion, induced abortion, birth, child care expenses) and cost of side effects. Contraception saves money by reducing unintended pregnancies and reducing transmission of sexually transmitted infections. By comparison, in the US, method related costs vary from nothing to about $1,000 for a year or more of reversible contraception.
Blood tests can be used to identify a response to acute infection (IgM) or previous infection and subsequent immunity (IgG). Prenatal diagnosis of fetal varicella infection can be performed using ultrasound, though a delay of 5 weeks following primary maternal infection is advised. A PCR (DNA) test of the mother's amniotic fluid can also be performed, though the risk of spontaneous abortion due to the amniocentesis procedure is higher than the risk of the baby's developing fetal varicella syndrome.
SSRI use in pregnancy has been associated with a variety of risks with varying degrees of proof of causation. As depression is independently associated with negative pregnancy outcomes, determining the extent to which observed associations between antidepressant use and specific adverse outcomes reflects a causative relationship has been difficult in some cases. In other cases, the attribution of adverse outcomes to antidepressant exposure seems fairly clear. SSRI use in pregnancy is associated with an increased risk of spontaneous abortion of about 1.7-fold.
About 30 percent of human conceptions do not progress to full term (22 percent before becoming clinical pregnancies) creating a second arena for conflict between the mother and the fetus. The fetus will have a lower quality cut off point for spontaneous abortion than the mother. The mother's quality cut-off point also declines as she nears the end of her reproductive life, which is significantly seen in older mothers. Older mothers have a higher incidence of offspring with genetic defects.
In 1975, the CDC published a study associating the Dalkon Shield with a higher risk of spontaneous abortion-related death compared to other IUDs. As many as 200,000 women made claims against the A.H. Robins company, mostly related to claims associated with pelvic inflammatory disease and loss of fertility. The company eventually filed for bankruptcy. The company's representatives argued that pelvic infections have a wide variety of causes, and that the Dalkon Shield was no more dangerous than other forms of birth control.
Transfusion-related immunomodulation refers to the transient depression of the immune system following transfusion of blood products. This effect has been recognized in groups of individuals who have undergone kidney transplantation or have had multiple miscarriages.Gatenby PA, Cameron K, Simes RJ, Adelstein S, Bennett MJ, Jansen RP, Shearman RP, Stewart GJ, Whittle M, Doran TJ. Treatment of recurrent spontaneous abortion by immunization with paternal lymphocytes: results of a controlled trial. Am J Reprod Immunol. 1993 Mar;29(2):88-94.
Invasive infection by L. monocytogenes causes the disease listeriosis. When the infection is not invasive, any illness as a consequence of infection is termed febrile gastroenteritis. The manifestations of listeriosis include sepsis, meningitis (or meningoencephalitis), encephalitis, corneal ulcer, pneumonia, and intrauterine or cervical infections in pregnant women, which may result in spontaneous abortion (second to third trimester) or stillbirth. Surviving neonates of fetomaternal listeriosis may suffer granulomatosis infantiseptica — pyogenic granulomas distributed over the whole body — and may suffer from physical retardation.
While the average adult citizen of an endemic region possesses some immunity to the parasite, pregnancy causes complications that leave the woman and fetus extremely vulnerable. The parasite interferes with transmission of vital substances through the fetal placenta, often resulting in stillbirth, spontaneous abortion, or dangerously low birth weight. The tragedy of malaria in developing countries, particularly sub-Saharan Africa, receives abundant attention from the international health community, but until recently PAM and its unique complications were not adequately addressed.
Problems may include an abnormal appearance, short height, low body weight, small head size, poor coordination, low intelligence, behavioral problems, hearing loss, and vision problems. Those affected are more likely to have trouble in school, legal problems, participate in high-risk behaviors, and have trouble with alcohol and recreational drug use. Alcohol use during pregnancy also can cause spontaneous abortion, stillbirth, low birthweight, and prematurity. Not all infants exposed to alcohol in utero will have defects related to the alcohol consumption.
A. pleuropneumoniae was found to be the causative agent for up to 20% of all bacterial pneumonia cases in swine. The main disease associated with this bacterium is porcine pleuropneumonia, a highly contagious respiratory disease, affecting primarily young pigs (usually less than 6 months). All of the symptoms and signs of porcine pleuropneumonia can be attributed to its virulence factors. The symptoms include respiratory distress, bloodstained discharge (usually frothy) from the mouth, fever, anorexia, mild diarrhea, cyanosis, lethargy, and spontaneous abortion in sows.
Analysis of cffDNA may provide earlier diagnosis of fetal conditions than current techniques. As cffDNA is found in maternal blood, sampling carries no associated risk of spontaneous abortion. cffDNA analysis has the same ethical and practical issues as other techniques such as amniocentesis and chorionic villus sampling. Some disadvantages of sampling cffDNA include a low concentration of cffDNA in maternal blood; variation in the quantity of cffDNA between individuals; a high concentration of maternal cell free DNA compared to the cffDNA in maternal blood.
Untreated celiac disease can cause spontaneous abortion (miscarriage), intrauterine growth restriction, small for gestational age, low birthweight and preterm birth. Often reproductive disorders are the only manifestation of undiagnosed celiac disease and most cases are not recognized. Complications or failures of pregnancy cannot be explained simply by malabsorption, but by the autoimmune response elicited by the exposure to gluten, which causes damage to the placenta. The gluten-free diet avoids or reduces the risk of developing reproductive disorders in pregnant women with celiac disease.
C. abortus is endemic among ruminants such as cows and sheep and has been associated with abortion in a horse, a rabbit, guinea pigs, mice, pigs and humans. Infected females shed bacteria near the time of ovulation, so C. abortus is transmitted orally and sexually among mammals. All C. abortus strains were isolated or PCR-amplified from the placenta or fetal organs after spontaneous abortion. C. abortus infection generally remains unapparent until an animal aborts late in gestation or gives birth to a weak or dead fetus.
It is generally safe for pregnant women to undergo laparoscopic cholecystectomy during any trimester of pregnancy. Early elective surgery is recommended for women with symptomatic gallstones to decrease the risk of spontaneous abortion and pre-term delivery. Without cholecystectomy, more than half of such women will have recurrent symptoms during their pregnancy, and nearly one in four will develop a complication, such as acute cholecystitis, that requires urgent surgery. Acute cholecystitis is the second most common cause of acute abdomen in pregnant women after appendectomy.
Serum antibodies against BK virus have also been found in spontaneous abortion affected women as well as in women who underwent voluntary interruption of pregnancy. The virus then disseminates to the kidneys and urinary tract where it persists for the life of the individual. It is thought that up to 80% of the population contains a latent form of this virus, which remains latent until the body undergoes some form of immunosuppression. Typically, this is in the setting of kidney transplantation or multi-organ transplantation.
In association with prematurity, growth in the womb is reduced, and low birth weight is connected to PCE. There are also data associating spontaneous abortion with cocaine use. Cocaine reduces the appetite and has been linked with reduced maternal weight gain during pregnancy; in addition, constriction of the blood vessels may further limit supply of nutrients to the fetus. Using cocaine while pregnant also heightens the chances of maternal and fetal vitamin deficiencies, respiratory distress syndrome for the baby, and infarction of the bowels.
Much depends on the nature of the mutation (i.e. which amino acid is replaced and where). Null mutations are much less common, these mutations produce either a completely dysfunctional enzyme, or no enzyme at all. Thus, missense mutations may be more common overall because they are less lethal than nonsense mutations; nonsense mutations may simply result in spontaneous abortion. The IVS8-1G>C is the most frequently reported mutation in DHCR7. This disrupts the joining of exons eight and nine, and results in the insertion of 134 nucleotides into the DHCR7 transcript.
Studies have shown self-compatibility of pollen to vary between Banksia species, with some but not all species inhibiting the growth of pollen tubes for pollen from its own flowers. A more likely form of self-incompatibility is the spontaneous abortion of fruits that have been self-fertilised. These could be caused either by the expression of lethal genes, or the expression of genes that, while not lethal, cause the maternal plant to abort. Genetic causes are thought to be a common form of self-incompatibility, because of the high genetic load of the genus.
The initial site of infection may be the tonsils, or possibly the gastrointestinal tract. The virus then remains latent in the gastrointestinal tract and can also infect the tubular epithelial cells in the kidneys, where it continues to reproduce, shedding virus particles in the urine. In addition, recent studies suggest that this virus may latently infect the human semen as well as the chorionic villi tissues. Serum antibodies against Human polyomavirus 2 have also been found in spontaneous abortion affected women as well as in women who underwent voluntary interruption of pregnancy.
Amendment 67 would not only restrict all access to birth control and abortions, but it would also subject any woman whose pregnancy did not result in a live birth, including women who have a miscarriage, to a criminal investigation. Huerta spent three decades advocating for safer working conditions with the UFW. A key part of her platform was reducing harmful pesticides. As her movement grew more feminist in nature, this became more important as pesticides cause pregnancy complications such as: decreased fertilitity, spontaneous abortion, stillbirth, and developmental abnormalities.
SSRI use in pregnancy has been associated with a variety of risks with varying degrees of proof of causation. As depression is independently associated with negative pregnancy outcomes, determining the extent to which observed associations between antidepressant use and specific adverse outcomes reflects a causative relationship has been difficult in some cases. In other cases, the attribution of adverse outcomes to antidepressant exposure seems fairly clear. SSRI use in pregnancy is associated with an increased risk of spontaneous abortion of about 1.7-fold, and is associated with preterm birth and low birth weight.
Retinol plays a crucial role in the growth and differentiation of various body tissues, and it has been previously characterized that embryos are extremely sensitive to alterations in retinol concentration that can lead to spontaneous abortion and malformations occurring during development. Within a mature animal, retinol is transported from the liver via the circulatory system while bound to RBP to the desired target tissue. RBP is also bound to a carrier protein, transthyretin. The process by which RBP releases retinol for cellular availability is still unknown and not concisely determined.
In the Summer Olympics NORCECA qualification tournament played in May in Tijuana, Baja California, Mexico, Castillo saw her team qualify for the 2012 Summer Olympics, winning the gold medal against the Cuban team. She earned awards for the Best Receiver and Best Libero of the competition. Later, she would confessed, that she played the tournament being pregnant and would not be able to play at the Olympic Games. But about one month later, the National Team doctor gynaecologist Albert Fiorinelli Milciades Camilo, announced that Castillo suffered a spontaneous abortion after 19 weeks of pregnancy.
Gender specific features also include enlarged clitoris and breasts, as well as ovarian cysts in affected females, and enlarged penis in affected males. In the Journal of Pediatric Medicine, Donohue and Uchida described affected sisters whose growth appeared to have ended in the seventh month of gestation, both born alive but dying before four months of age. Very early death (or spontaneous abortion) is the norm, although sufferers sometimes live longer than a decade. Endocrine related abnormalities as a result of insulin receptor malfunction include insulin resistance, hypoglycemia and hyperglicemia (depending on whether or not the individual has eaten) and hyperinsulemia.
S. warneri has been suggested as a cause of spontaneous abortion in cattle and humans.Barigye R, Schaan L, Gibbs PS, Schamber E, Dyer, NW (2007). Diagnostic evidence of Staphylococcus warneri as a possible cause of bovine abortion. J. Vet. Diagn. Invest. 19(6): 694-696 It has been associated with vertebral discitis,Announ N., Mattei J., Jaoua S., Fenollar F., Sati H., Chagnaud C., Roudier J., Guis S. (2004) Multifocal discitis caused by Staphylococcus warneri. Joint Bone Spine 71 (3) 240-242 urinary tract infection,Leighton PM, Little JA. (1986) Identification of coagulase-negative Staphylococci isolated from urinary tract infections.
There were also anecdotal reports linking mercaptopurine with spontaneous abortion, leading to the US FDA rating both AZA and mercaptopurine as category D drugs. However, Davis et al. 1999 found mercaptopurine, compared to methotrexate, was ineffective as a single-agent abortifacient; every woman in the mercaptopurine arm of the study had fetal cardiac activity at follow-up (two weeks later) and was given a suction abortion. A more recent, larger study, however, performed by the Cancers et Surrisque Associe aux Maladies inflamatoires intestinales En France (CESAME) indicated an overall rate of congenital malformations not significantly greater than the general population in France.
Warfarin is contraindicated in pregnancy, as it passes through the placental barrier and may cause bleeding in the fetus; warfarin use during pregnancy is commonly associated with spontaneous abortion, stillbirth, neonatal death, and preterm birth. Retrieved on 15 December 2008 through Google Book Search. Coumarins (such as warfarin) are also teratogens, that is, they cause birth defects; the incidence of birth defects in infants exposed to warfarin in utero appears to be around 5%, although higher figures (up to 30%) have been reported in some studies. Depending on when exposure occurs during pregnancy, two distinct combinations of congenital abnormalities can arise.
A mink, one of the hosts of Carnivore amdoparvovirus 1 Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in minks and ferrets. It is caused by Carnivore amdoparvovirus 1 (also known as Aleution disease virus, ADV), a highly contagious parvovirus in the genus Amdoparvovirus. The virus has been found as a natural infection in the Mustelidae family within mink, ferrets, otters, polecats, stone and pine martens and within other varying carnivores such as skunks, genets, foxes and raccoons. This is most commonly explained as because they all share resources and habitats.
Social stress and resource limitation can lead to high rates of spontaneous abortion as a mechanism of reproductive suppression. Meerkats subordinate females that have conceived prior to being evicted from the group by the breeding female during the breeding season fail to carry their pregnancies as a result of increased stress (higher GC levels) and reduced access to food and other resources. Evicted females regularly copulate with males from neighboring groups Subordinate females have low conception rates and increased abortion rates in response to low food availability and high predation risk. Dwarf mongooses show synchronous estrous but only the dominant female regularly bears young.
Treatment of breast cancer during pregnancy also involves fetal considerations, because lumpectomy is discouraged in favor of modified radical mastectomy unless late-term pregnancy allows follow-up radiation therapy to be administered after the birth. Exposure to a single chemotherapy drug is estimated to cause a 7.5–17% risk of teratogenic effects on the fetus, with higher risks for multiple drug treatments. Treatment with more than 40 Gy of radiation usually causes spontaneous abortion. Exposure to much lower doses during the first trimester, especially 8 to 15 weeks of development, can cause intellectual disability or microcephaly, and exposure at this or subsequent stages can cause reduced intrauterine growth and birth weight.
Evidence about radiation-related pregnancy and birth outcomes comes from studies of nuclear bomb and test site survivors and studies of those exposed to diagnostic and therapeutic radiation. Mounting research indicates that above certain levels of radiation a miscarriage will result. It is also clear that fetal malformations are a greater risk if a woman is exposed to high doses of nuclear-related radiation in early pregnancy, when organs are being formed. If acute radiation exposure occurs in the first ten days following conception, when few cells have formed, it is likely that the embryo will fail to develop and spontaneous abortion will occur.
According to the U.S. Food and Drug Administration pregnancy categories, levothyroxine has been assigned category A. Given that no increased risk of congenital abnormalities has been demonstrated in pregnant women taking levothyroxine, therapy should be continued during pregnancy. Furthermore, therapy should be immediately administered to women diagnosed with hypothyroidism during pregnancy, as hypothyroidism is associated with a higher rate of complications, such as spontaneous abortion, preeclampsia, and premature birth. Thyroid hormone requirements increase during and last throughout pregnancy. As such, pregnant women are recommended to increase to nine doses of levothyroxine each week, rather than the usual seven, as soon as their pregnancy is confirmed.
Ibuprofen and naproxen have not frequently been studied during pregnancy, but recent studies do not show increased risk of spontaneous abortion within the first six weeks of pregnancy. However, all NSAIDs showed association with structural cardiac defects with usage during the early weeks of pregnancy. When ibuprofen and naproxen are used within the third trimester, there is a significant increase in the risk of premature closure of the ductus arteriosus with primary pulmonary hypertension in the newborn. Between the lack of studies of the effect of ibuprofen and naproxen on pregnancy, it is recommended that pregnant women avoid these medications or use them sparingly per physician recommendations.
Rarely, congenital malformations, intrauterine devices, certain cancers, and pelvic infections cause secondary dysmenorrhea. If the pain occurs between menstrual periods, lasts longer than the first few days of the period, or is not adequately relieved by the use of non-steroidal anti-inflammatory drugs (NSAIDs) or hormonal contraceptives, women should be evaluated for secondary causes of dysmenorrhea. When severe pelvic pain and bleeding suddenly occur or worsen during a cycle, the woman or girl should be evaluated for ectopic pregnancy and spontaneous abortion. This evaluation begins with a pregnancy test and should be done as soon as unusual pain begins, because ectopic pregnancies can be life‑threatening.
The reframing of miscarriage as a private emotional experience brought less awareness of miscarriage and a sense of silence around the subject, especially compared to the public discussion of miscarriage during campaigns for access to birth control during the early 20th century, or the public campaigns to prevent miscarriages, stillbirths, and infant deaths by reducing industrial pollution during the 1970s. In places where induced abortion is illegal or carries social stigma, suspicion may surround miscarriage, complicating an already sensitive issue. In the 1960s, the use of the word miscarriage in Britain (instead of spontaneous abortion) occurred after changes in legislation. Developments in ultrasound technology (in the early 1980s) allowed them to identify earlier miscarriages.
The subtypes of pFAS are alcohol-related neurodevelopmental disorder (ARND) and alcohol-related birth defects (ARBD). In addition to FAS, pFAS, ARND, and ARBD, any other conditions believed to be related to prenatal alcohol exposure, such as spontaneous abortion and sudden infant death syndrome (SIDS), are also considered to be on the spectrum of related disorders. It is unclear if identifying a FASD-related condition benefits the individual. In 2013, the American Psychiatric Association introduced, neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE) into the DSM-V as a "condition for further study" and as a specified condition under, "other specified neurodevelopmental disorders" as a way to better study the behavioral aspects of all FASD disorders.
Some vitamins are toxic in high doses and nearly all (with the possible exception of Vitamin C) will cause adverse effects given high levels of overdosing for prolonged periods as recommended by orthomolecular practitioners. Forgoing medical care in favor of orthomolecular treatments can lead to adverse health outcomes. Health professionals see orthomolecular medicine as encouraging individuals to dose themselves with large amounts of vitamins and other nutrients without conventional supervision, which they worry might be damaging to health. Potential risks of inappropriate vitamin and supplement regimes include an increased risk of coronary heart disease, hypertension, thrombophlebitis, peripheral neuropathy, ataxia, neurological effects, liver toxicity, congenital abnormalities, spontaneous abortion, gouty arthritis, jaundice, kidney stones, and diarrhea.
DES (diethylstilbestrol) is a drug that mimics estrogen, a female hormone. From 1938 until 1971 doctors prescribed this drug to help some pregnant women who had had miscarriages or premature deliveries on the theory that miscarriages and premature births occurred because some pregnant women did not produce enough estrogen naturally to sustain the pregnancy for full term . An estimated 5-10 million pregnant women and the children born during this period were exposed to DES. Currently, DES is known to increase the risk of breast cancer, and cause a variety of birth- related adverse outcomes exposed female offsprings such as spontaneous abortion, second-trimester pregnancy loss, preterm delivery, stillbirth, neonatal death, sub/infertility and cancer of reproductive tissues .
Ulubelen's research focuses on isolation, structure determination, and pharmacological investigation of Turkish plants and compounds isolated from them, and especially on isolates from plants abundant in Turkey and mentioned in Turkish folklore and medicine. Her work with triterpenes and flavonoids was followed by work on diterpenoids, to find plant components that produce various medical effects including spontaneous abortion and wound healing. During tests on mice, Ulubelen found an abortive factor developing cystic degeneration in the ovaries, but was unsure whether the effect was caused by the abortive agent or by some other compound. Ten compounds from the source plant were studied, including screening by a Faculty of Medicine group for toxic effects to the ovaries, livers, kidneys, and brain.
This scar tissue can be massaged or broken up in a number of ways, thus allowing the cervical opening to dilate back to normal size. A cohort study came to the result that women with a time interval from LEEP to pregnancy of less than 12 months compared with 12 months or more were at significantly increased risk for spontaneous abortion, with risk of miscarriage of 18% compared with 4.6%, respectively. On the other hand, no increased risk was identified for preterm birth after LEEP. However a large meta-analysis concluded that women with CIN have a higher baseline risk for preterm birth than the general population and that LEEP as the treatment for CIN probably increase this risk further.
He is distraught when Emily is suffering a spontaneous abortion and tries to contact her, but Bruce at first and then Robert prevent him from it, the former to protect him from Robert's fury and the latter to "protect" Emily from him. He ends up going to Tulane, followed by Emily, to be a doctor. Harris' Father A good natured policeman, the only man aside from Tom and Bruce who has stood up to Robert and told him head on that he knows of the abuse but due to respect and steem for Emily and Lynn he never proceeded with the reports of violence from their neighbours. He cares deeply for his son and tries to protect him from Robert.
The signs shown depend on the horse's age, the strain of the infecting virus, the condition of the horse and the route by which it was infected. Most horses with EVA infection do not show any signs; if a horse does show signs, these can vary greatly in severity. Following infection, the first sign is fever, peaking at , followed by various signs such as lethargy, nasal discharge, "pink eye" (conjunctivitis), swelling over the eye (supraorbital edema), urticaria, and swelling of the limbs and under the belly (the ventral abdomen) which may extend to the udder in mares or the scrotum of male horses. More unusual signs include spontaneous abortion in pregnant mares, and, most likely in foals, severe respiratory distress and death.
In premenopausal women, bleeding may occur as a result of a pregnancy complication, such as a spontaneous abortion, ectopic pregnancy, or abnormal growth of the placenta, even if the woman is not aware of the pregnancy. This possibility must be kept in mind with regard to diagnosis and management. In addition, the possibility that the bleeding does not arise from the uterus itself must be kept in mind, and a gynecologic examination should be performed to look for vulvar or vaginal lesions, and cervical causes of bleeding such as cervicitis from an STI. The causes of abnormal uterine bleeding in premenopausal women who are not pregnant have been classified using the FIGO (International Federation of Gynecology and Obstetrics) PALM-COEIN system.
In November 1994, Daling published a case-control study in the Journal of the National Cancer Institute which found that induced, but not spontaneous, abortion was associated with a 50% increased risk of breast cancer. The study also found that the highest increase in risk was among women who had an abortion in the last month of the first trimester. However, Daling cautioned against drawing a firm conclusion at the time, and told the Seattle Post-Intelligencer that "I'm concerned that this will be used to alarm people." Two years later she co-authored another study on the same topic that found a smaller increase in risk (relative risk 1.2) and no evidence of a higher increase in risk among any subgroups.
Heavy menstrual bleeding since menarche is a common symptom for women with bleeding disorders, and in retrospective studies, bleeding disorders have been found in up to 62% of adolescents with heavy menstrual bleeding. Ovulatory dysfunction or anovulation is a common cause of abnormal bleeding that may lead to irregular and unpredictable bleeding, as well as variations in the amount of flow including heavy bleeding. Endocrine causes of ovulatory disorders include polycystic ovary syndrome (PCOS), thyroid disorders, hyperprolactinemia, obesity, eating disorders including anorexia nervosa or bulimia, or to an imbalance between exercise and caloric intake. Endometrial causes of abnormal bleeding include infection of the endometrium, endometritis, which may occur after a miscarriage (spontaneous abortion) or a delivery, or may be related to a sexually-transmitted infection of the uterus, fallopian tubes or pelvis generally termed pelvic inflammatory disease (PID).
Her dream is to become a social worker or a doctor, and thus help abused women like her mother realize that they are living in a bad situation and to try to get them out of it. She has a steady boyfriend named Harris, who her father hates and disapproves of due to their difference in social class, yet Emily ignores that and loves Harris for who he is. In the middle of te novel she has a spontaneous abortion after three months of pregnancy and has to be rushed to the ER, resulting in her losing the baby and her father on tightening his grip on her as much as he could, prohibiting her from seeing Harris ever again. She refuses to go to the university his father wants her to go and instead makes plans to go to the same university as Harris.
DES-exposed daughters are at an increased risk of abnormalities of the reproductive tract, including vaginal epithelial changes such as vaginal adenosis (which means a type of cell normally found in the uterus, columnar cells, are also present in the vagina), an increased cervical transformation zone, and uterine abnormalities, such as T-shaped uterus. These anomalies contribute to an increased risk of infertility and adverse pregnancy outcomes in prenatally DES-exposed daughters. The most recent published research on DES daughters' adverse health outcomes documented by the U.S. National Cancer Institute (NCI) appears in the October 6, 2011 issue of the New England Journal of Medicine under the authorship of RN Hoover et al., and lists these adverse effects and risk factors: Cumulative risks in women exposed to DES, as compared with those not exposed, were as follows: for infertility, 33.3% vs. 15.5%; spontaneous abortion, 50.3% vs.

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