And today's word is "sequelae": the harmful or unexpected aftereffects of a disease or trauma.
|
|
Her use of the term "sequelae" prompted Merriam-Webster dictionary to tweet the meaning of the word.
|
|
O'Neill died of sequelae of chronic ethanol (alcohol) overconsumption, an L.A. County Coroner's Office spokeswoman tells PEOPLE.
|
|
Puerto Ricans, Floridians and many other Americans are justifiably terrified of the life-altering sequelae of Zika infection.
|
|
She spoke by turns as a victim and a professional, interspersing her testimony with medical terms: norepinephrine, epinephrine, sequelae.
|
|
Regardless, the attempts to stop the perpetration or escape or avoid the physical, emotional, and interpersonal sequelae are prevalent.
|
|
"I think the sequelae of sexual assault varies per person," Dr. Blasey told the committee, using a scientific term for aftereffects.
|
|
In recent decades, diseases such as measles have reappeared in countries where they had been nearly eradicated, with serious, even fatal sequelae.
|
|
The L.A. County Coroner's Office released an autopsy report Wednesday saying the 'Austin Powers' star died of "sequelae of alcohol intoxication" ... basically alcohol abuse.
|
|
The autopsy by El Paso County's medical examiner, found that Caal died of "sequelae of Streptococcal sepsis," an often deadly reaction to infection or bacteria.
|
|
The L.A. County Coroner's Office spokeswoman previously told PEOPLE O'Neill, who played Hugh on the critically acclaimed series, died of sequelae of chronic ethanol (alcohol) overconsumption.
|
|
Not only the rapes but all the sequelae: the agony, the bitterness, the self-recrimination, the asco, the desperate need to keep it hidden and silent.
|
|
Drugs are very effective in keeping patients with chronic diseases out of hospitals and in reducing surgical procedures to address the sequelae of end-stage chronic diseases.
|
|
Troyer, who was 49, died from sequelae of alcohol intoxication, according to a press release obtained by PEOPLE from the Los Angeles County Department Medical Examiner-Coroner's office.
|
|
" Ford said she disclosed the details of the alleged assault "in the confines of therapy where I felt like it was an appropriate place to cope with the sequelae of the event.
|
|
On Thursday, Ford's expertise in her own trauma was clear, helping propel her testimony even as the deck was stacked against her: She dropped terms like "sequelae" and explained "fight-or-flight" in great detail.
|
|
Hundreds of millions more are adversely affected by climate crisis-related heart, kidney and lung disease, numerous water- and vector-borne diseases, mental health sequelae, and declines in both the quantity and nutritional value of significant foodstuffs.
|
|
The current leftist critique, lit by the inevitable disillusion of the post-Obama period, is one of absolute original sin—the sins of the Constitutional Convention, with its "three-fifths compromise," reinforced by the evils of Reconstruction and Jim Crow and its sequelae.
|
|
Dianne Feinstein asked Ford about the impact the events had on her, Ford replied: Well, I think that the sequelae of sexual assault varies by person so for me personally, anxiety, phobia and PTSD-like symptoms are the types of things I've been coping with.
|
|
His research, using the American Society of Anesthesiologists' Anesthesia Awareness Registry, a voluntary registry of patients with memories under conscious sedation or general anesthesia, showed that 78 percent of those reporting awareness under conscious sedation felt distress, and 40 percent had long-term psychological sequelae, including post-traumatic stress disorder.
|
|
That order is built, to an extent that would have been unfathomable even 20 years ago, on the commercial exploitation of what was once called "genre" entertainment — the comic-book movie especially, the Marvel empire above all, with a wider range of science fiction and fantasy blockbusters and sequelae around that superhero core.
|
|
The overall prognosis of ARDS is poor, with mortality rates of approximately 40%. Exercise limitation, physical and psychological sequelae, decreased physical quality of life, and increased costs and use of health care services are important sequelae of ARDS.
|
|
This may lead to various neurological sequelae including presentation with cerebral palsy, mental retardation and seizures.
|
|
Immediate complications during the surgical procedure, e.g. bleeding or perforation of organs may have lethal sequelae.
|
|
Since neurologic and developmental difficulties have not been reported as a consequence of neuroblastoma or its treatment, it is thought that these are exclusively due to the immune mechanism underlying OMS. One study concludes that: "Patients with OMA and neuroblastoma have excellent survival but a high risk of neurologic sequelae. Favourable disease stage correlates with a higher risk for development of neurologic sequelae. The role of anti-neuronal antibodies in late sequelae of OMA needs further clarification".
|
|
An organisation that treats infants and mothers suffering from sequelae, caused by alcohol and drug addiction during pregnancy.
|
|
A sequela (, ;from Latin sequela, from sequi ("follow") usually used in the plural, sequelae ) is a pathological condition resulting from a disease, injury, therapy, or other trauma. A typical sequela is a chronic complication of an acute condition - in other words, a long-term effect of a temporary disease or injury - which follow immediately from the condition. Sequelae differ from late effects, which can appear long after - even several decades after - the original condition has resolved. In general, non-medical usage, the terms sequela and sequelae mean consequence and consequences.
|
|
However, a follow-up study has shown that most survivors recover completely without any sequelae if treated within 36 hours of mushroom ingestion.
|
|
Sequelae can appear early in the development of disease or weeks to months later and are a result of the initial injury or illness. For example, a scar resulting from a burn or dysphagia resulting from a stroke would be considered sequelae. In addition, complications should not be confused with comorbidities, which are diseases that occur concurrently but have no causative association.
|
|
Commotio retinae is usually self limiting and there is no treatment as such. It usually resolves in 3–4 weeks without any complications and sequelae.
|
|
Monitoring bowel function and the preemptive use of laxatives for all clozapine-treated people has been shown to improve colonic transit times and reduce serious sequelae.
|
|
Sequelae of prematurity can be reduced to a small extent by using drugs to accelerate maturation of the fetus, and to a greater extent by preventing preterm birth.
|
|
The petechial rash appear with the 'star-like' shape. Meningococcal sepsis has a greater mortality rate than meningococcal meningitis, but the risk of neurologic sequelae is much lower.
|
|
Homesickness in preadolescent and adolescent girls: Risk factors, behavioral correlates, and sequelae. Journal of Clinical Child Psychology, 28, 185–196.Thurber, C.A. (1999). The phenomenology of homesickness in boys.
|
|
Turner currently works in the film industry as an Actor and Stunt Performer. He has been an active supporter of research on long-term sequelae of traumatic brain injury.
|
|
In the perspective of physical rehabilitation, the most serious sequelae after acute bacterial meningitis are neurological including motor impairment, epilepsy, cecity or vision loss, speech disorder and hearing loss.
|
|
Through his efforts, the number of SCI centers increased in the US, as well as the staff-to-patient ratio. Bors authored more than 140 scientific papers and a major textbook, co-authored by Estin Comarr and titled, Neurological Urology, Physiology of Micturition, its Neurological Disorders and Sequelae, which remains the authoritative text in this field.Bors EHJ, Comarr AE. Neurological Urology, Physiology of Micturition, Its Neurological Disorders and Sequelae. Location, Publisher, Date.
|
|
An example is pleurisy. Other examples of sequelae include those following neurological injury; including aphasia, ataxia, hemi- and quadriplegia, and any number of other changes that may be caused by neurological trauma. Note that these pathologies can be related to both physical and chemical traumas, as both can cause lingering neuron damage. The phrase status post, abbreviated in writing as s/p, is used to discuss sequelae with reference to their cause.
|
|
Kagee, A., & Naidoo, A. V. (2004). Reconceptualizing the sequelae of political torture: Limitations of a psychiatric paradigm. Transcultural Psychiatry, 41(1), 46-61.Bracken, P. J., Giller, J. E., & Summerfield, D. (1995).
|
|
It gains entry typically by abrasions in the hand. Bacteremia and endocarditis are uncommon but serious sequelae. Due to the rarity of reported human cases, E. rhusiopathiae infections are frequently misidentified at presentation.
|
|
Hypnic jerks are common physiological phenomena. Around 70% of people experience them at least once in their lives with 10% experiencing it daily. They are benign and do not cause any neurological sequelae.
|
|
In late 2017, Gouveia suffered a stroke that left him with lifelong sequelae. On May 29, 2020, Gouveia died in Fortaleza at the age 91 due to complications brought on by COVID-19.
|
|
Early intervention and restoration of adequate nutrition has been shown to reduce the likelihood of long-term sequelae, however, studies have shown that failure to thrive may cause persistent behavioral problems, despite appropriate treatment.
|
|
Atrophy of the optic nerve can also cause blindness in fetal warfarin syndrome.Raghav, S. & Reutens, D. 2006;2007;, "Neurological sequelae of intrauterine warfarin exposure", Journal of Clinical Neuroscience, vol. 14, no. 2, pp. 99-103.
|
|
Chronic kidney disease, for example, is sometimes a sequela of diabetes, "chronic constipation" or more accurately "obstipation" (that is, difficulty in passing stool) is a sequela to an intestinal obstruction, and neck pain is a common sequela of whiplash or other trauma to the cervical vertebrae. Post-traumatic stress disorder may be a psychological sequela of rape. Sequelae of traumatic brain injury include headache and dizziness, anxiety, apathy, depression, aggression, cognitive impairments, personality changes, mania, psychosis. Some conditions may be diagnosed retrospectively from their sequelae.
|
|
When a patient suffers from sensory impairment, and when the clinical localization of the sensory impairment is unclear, SEPs can be helpful in distinguishing whether the sensory impairment is due to CNS problems as opposed to peripheral nervous system problems. Median nerve SEP is also helpful in predicting neurological sequelae following cardiac arrest: if the cortical N20 and subsequent components are completely absent 24 hours or more after the cardiac arrest, essentially all of the patients go on to die or have vegetative neurological sequelae.
|
|
Depression may occur in those who did not have pre-existing depression. These delayed neurological sequelae may occur in up to 50% of poisoned people after 2 to 40 days. It is difficult to predict who will develop delayed sequelae; however, advanced age, loss of consciousness while poisoned, and initial neurological abnormalities may increase the chance of developing delayed symptoms. One classic sign of carbon monoxide poisoning is more often seen in the dead rather than the living – people have been described as looking red-cheeked and healthy (see below).
|
|
Mood disorders have also been known to correlate with auditory hallucinations, but tend to be milder than their psychosis-induced counterpart. Auditory hallucinations are a relatively common sequelae of major neurocognitive disorders (formerly dementia) such as Alzheimer's disease.
|
|
Symonds CP. Concussion and contusion of the brain and their sequelae. In: Brock S, ed. Injuries of the Skull, Brain and Spinal Cord: Neuro-Psychiatric, Surgical, andMedico-Legal Aspects. London, UK: Bailliere, Tindall and Cox; 1940:69–111.
|
|
The liver and kidney are most commonly damaged by leptospirosis. Vasculitis can occur, causing edema and potentially disseminated intravascular coagulation (DIC). Myocarditis, pericarditis, meningitis, and uveitis are also possible sequelae. Ixodes scapularis Brucellosis in dogs is caused by Brucella canis.
|
|
Other possibilities resulting from brain stem distortion include lethargy, slow heart rate, and pupil dilation. Uncal herniation may advance to central herniation. The sliding uncus syndrome represents uncal herniation without alteration in the level of consciousness and other sequelae mentioned above.
|
|
Achalasia is a motor disorder of the esophagus characterized by decrease in ganglion cell density in the myenteric plexus. The cause of the lesion is unknown. Myenteric plexi destruction has been found to be secondary to Chagas disease (T. cruzi infection sequelae).
|
|
Andreas Maercker (born 26 April 1960) is a German clinical psychologist and international expert in traumatic stress-related mental disorders who works in Switzerland. He also contributed to lifespan and sociocultural aspects of trauma sequelae, e.g. the Janus-Face model of posttraumatic growth.
|
|
Late in his life, Jerman became interested in the application of X-rays to fields like botany, zoology and paleontology. After retiring in 1934, Jerman died two years later. In his final months, he dealt with painful sequelae of frequent X-ray exposure.
|
|
No serious clinical sequelae resulted from participation. In women with cancer, a testing for the level of anti-Müllerian hormone (AMH) is useful in predicting the long-term post-chemotherapy loss of ovarian function, in turn predicting the need for fertility preservation strategies.
|
|
It has been reported that electroconvulsive therapy (ECT) may increase the likelihood of delayed neuropsychiatric sequelae (DNS) after carbon monoxide (CO) poisoning. A device that also provides some carbon dioxide to stimulate faster breathing (sold under the brand name ClearMate) may also be used.
|
|
Human experience of acute overdose with zileuton is limited. A patient in a clinical study took between 6.6 and 9.0 grams of zileuton immediate-release tablets in a single dose. Vomiting was inducted and the patient recovered without sequelae. Zileuton is not removed by dialysis.
|
|
Newman continuously emphasized the humanitarian aspects of dealing with the drug-dependent patients. Newman was married to Seiko Newman, born Kusuba; they have two children. In June 2018, Newman was victim of a car accident in The Bronx, of which sequelae he finally died.
|
|
The most serious complication is intracranial hemorrhage, leading to death in approximately 10% of symptomatic babies or neurologic sequelae in 20% of cases. 80% of intracranial hemorrhages occur before birth. After birth the greatest risk of bleeding is in the first four days of life.
|
|
Treatment includes anti-inflammatory medications and immobilization of the neck in addition to treatment of the offending infectious cause (if any) with appropriate antibiotics. Early treatment is crucial to prevent long-term sequelae. Surgical fusion may be required for residual instability of the joint.
|
|
There are many other ailments that show similar symptoms to ED. Differential diagnosis are as follows; retinopathy of prematurity (ROP) sequelae, familial exudative vitreoretinopathy, sarcoidosis, Behçet disease, sickle cell anemia, Terson syndrome, post traumatic vitreous hemorrhage, juvenile diabetes and primary branch retinal vein occlusion.
|
|
Some intestinal parasitic infections may play a role in irritable bowel syndrome and other long-term sequelae such as chronic fatigue syndrome.Quote: "for unclear reasons, chronic sequelae, including post- infectious irritable bowel syndrome, chronic fatigue [..], malnutrition [..], cognitive impairment [..], and extra-intestinal manifestations (such as food allergy, urticaria, reactive arthritis, and inflammatory ocular manifestations), can develop and possibly persist beyond detectable parasite shedding". Quoted from: The mechanism of transformation from cyst to trophozoites has not been characterized but may be helpful in developing drug targets for treatment-resistant Giardia. The interaction between Giardia and host immunity, internal flora, and other pathogens is not well understood.
|
|
Indeed, histamine release has been reported with administration of pancuronium. The liberation of histamine is a dose-dependent phenomenon such that, with increasing doses administered at the same rate, there is a greater propensity for eliciting histamine release and its ensuing sequelae. Most commonly, the histamine release following administration of these agents is associated with observable cutaneous flushing (facial face and arms, commonly), hypotension and a consequent reflex tachycardia. These sequelae are very transient effects: the total duration of the cardiovascular effects is no more than one to two minutes while the facial flush may take around 3–4 minutes to dissipate—(note: half-life of plasma histamine is ~2 minutes).
|
|
The neuropsychiatric sequelae following brain injuries could include diffuse cognitive impairment, with more prominent deficits in the rate of information processing, attention, memory, cognitive flexibility, and problem solving. Prominent impulsivity, affective instability, and disinhibition are seen frequently, secondary to injury to frontal, temporal, and limbic areas. In association with the typical cognitive deficits, these sequelae characterise the frequently noted "personality changes" in TBI (Traumatic Brain Injury) patients. Disinhibition syndromes, in brain injuries and insults including brain tumors, strokes and epilepsy range from mildly inappropriate social behaviour, lack of control over one's behaviour to the full-blown mania, depending on the lesions to specific brain regions.
|
|
A symblepharon is a partial or complete adhesion of the palpebral conjunctiva of the eyelid to the bulbar conjunctiva of the eyeball. It results either from disease (conjunctival sequelae of trachoma) or trauma. Cicatricial pemphigoid and, in severe cases, rosacea may cause symblepharon. It is rarely congenital.
|
|
Fredrickson, B. L. & Levenson, R. W. (1998). Positive emotions speed recovery from the cardiovascular sequelae of negative emotions. Cognition and Emotion, 12, 191-220. According to this view, positive emotions have a unique ability to down-regulate lingering negative emotions and the psychological and physiological states they generate.
|
|
O. Souza Lopes, Francisco P. Pinheiro, and L. B. Iversson: "Rocio Viral Encephalitis", in: Handbook of Zoonoses, Second Edition, Section B: Viral Zoonoses, George W. Beran (ed.-in-ch.), CRC Press, 1994, pp. 205–209. Survivors show neurological and psychological after-effects (sequelae) in about 20% of cases.
|
|
In 1931, von Economo died in Vienna, aged 55, of the sequelae of a heart attack. He was honored by an Austrian stamp in 1976. Since 1966, a bust portraying him can be found in the "Arkadenhof" of the University of Vienna. Van Bogaert, L., Théodoridès, J. (1979).
|
|
From around the world other Military doctors visit Birmingham General Hospital to learn about this new traumatic spinal cord center.The American Paraplegia Society 1954-2004: Our legacy, our future. J Spinal Cord Med. 2004;27(4):287-303.Bors EHJ, Comarr AE. Neurological Urology, Physiology of Micturition, Its Neurological Disorders and Sequelae.
|
|
Early signs of perforation were present in only 51% of perforation claims, whereas late sequelae occurred in 65%. During the SARS and COVID-19 pandemics, tracheal intubation has been used with a ventilator in severe cases where the patient struggles to breathe. However, the procedure carries risk of infecting the caregiver.
|
|
In the Colombian states of Antioquia and Chocó, it causes 50-70% of all snakebites, with a sequelae rate of 6% and a fatality rate of 5% (Otero et al., 1992). In the state of Lara, Venezuela, it is responsible for 78% of all envenomations and all snakebite fatalities (Dao-L.
|
|
In modern times, commercial advertising pressures have altered the public's attitude towards problems such as halitosis, which have taken on greater negative psychosocial sequelae as a result. For example, in the United States, a poll reported that 55–75 million citizens consider bad breath a "principal concern" during social encounters.
|
|
Primary bacteraemia, infection without identifiable focal origin, comprises approximately 20% of the reported cases. Recently, Streptococcus dysgalactiae subspecies equisimilis has been linked to post-streptococcal glomerulonephritis and acute rheumatic fever. These immunologic sequelae have previously only been associated with Streptococcus pyogenes. Streptococcus dysgalactiae subspecies dysgalactiae is almost exclusively an animal pathogen.
|
|
Dystrophic calcinosis cutis has also been reported. Other serious sequelae include sialolithiasis of the submandibular gland and adenolymphoma of the parotid gland. The histopathology of fiddler's neck frequently shows hyperkeratosis and acanthosis, along with plugging of follicles. Histiocytic infiltration with granulomas to foreign body and follicular cysts are also common.
|
|
This is reported to cause collateral flow paths to open up to drain the left kidney i.e. reversed flow (reflux caudally) in the left renal vein. Pelvic Congestion Syndrome, vaginal and vulval varices, lower limb varices are clinical sequelae. Virtually all such patient are female and have been pregnant, often multiply.
|
|
Herek, G. M., Gillis, J. R., & Cogan, J. C. (1999). Psychological sequelae of hate-crime victimization among lesbian, gay, bisexual and transgender adults. Journal of Consulting and Clinical Psychology, 67, 945-951.GLSEN. (1999). GLSEN’s national school climate survey: Lesbian, gay, bisexual and transgender students and their experiences in school.
|
|
Either alcohol ablation or myectomy offers substantial clinical improvement for patients with hypertrophic obstructive cardiomyopathy. One non-randomized comparison suggested that hemodynamic resolution of the obstruction and its sequelae are more complete with myectomy. Whether one or the other treatment is preferable for certain patient types is debated among cardiovascular scientists.
|
|
The disease is also seen in countries of South America. WEE is commonly a subclinical infection; symptomatic infections are uncommon. However, the disease can cause serious sequelae in infants and children. Unlike Eastern equine encephalitis, the overall mortality of WEE is low (approximately 4%) and is associated mostly with infection in the elderly.
|
|
While corticosteroids are often used, evidence to support this is poor. Salicylates are useful for pain. Steroids are reserved for cases where there is evidence of an involvement of the heart. The use of steroids may prevent further scarring of tissue and may prevent the development of sequelae such as mitral stenosis.
|
|
A typical patient with severe McLeod syndrome that begins in adulthood lives for an additional 5 to 10 years. Patients with cardiomyopathy have elevated risk for congestive heart failure and sudden cardiac death. The prognosis for a normal life span is often good in some patients with mild neurological or cardiac sequelae.
|
|
In 1931 Frederick Griffith coauthored a paper on acute tonsillitis—its sequelae, epidemiology, and bacteriology. In 1934, Griffith reported voluminous findings on the serological typing of Streptococcus pyogenes. More casually as well as medically called simply streptococcus,Kenneth Todar "Streptococcus pyogenes and streptococcal disease (page 1) ". Todar's Online Textbook of Bateriology. 2008.
|
|
When a patient has multiple abnormalities (multiple anomaly, multiple deformity), they have a congenital abnormality that can not be primarily identified with a single system of the body or single disease process. Most medical conditions can have systemic sequelae, but multiple abnormalities occur when the effects on multiple systems is immediately obvious.
|
|
In Japan, ibudilast oral capsules are approved for the treatment of asthma, and for improvement of dizziness secondary to chronic cerebral circulation impairment associated with sequelae of cerebral infarction. Ibudilast ophthalmic solution is indicated for the treatment of allergic conjunctivitis and hay fever. It may have some use reducing methamphetamine, opioid, and alcohol addiction.
|
|
Portal venous pressure is the blood pressure in the hepatic portal vein, and is normally between 5-10 mmHg.eMedicine - "Esophageal Varices" Raised portal venous pressure is termed portal hypertension,Ascites in Cirrhosis Relative Importance of Portal Hypertension and Hypoalbuminemia DONALI) O. CASTELL, LCDR (MC), USN and has numerous sequelae such as ascites and hepatic encephalopathy.
|
|
Death has occurred in four of 107 confirmed cases. In a few cases, permanent sequelae included short-term memory loss and peripheral polyneuropathy. No antidote for domoic acid is known, so if symptoms fit the description, immediate medical attention is advised. Cooking or freezing affected fish or shellfish tissue does not lessen the toxicity.
|
|
When young, it may be mistaken for the edible St George's mushroom (Calocybe gambosa) or the miller (Clitopilus prunulus). It has been responsible for many cases of mushroom poisoning in Europe. E. sinuatum causes primarily gastrointestinal problems that, though not generally life- threatening, have been described as highly unpleasant. Delirium and depression are uncommon sequelae.
|
|
Prognosis can vary heavily based on the severity of the neurological dysfunction. If treatment is initiated early in disease the neurologic sequelae may be reversed and further deterioration can be prevented. Long-term outlook is reasonably good for most people when diagnosed and treated early. A case study presented a female patient diagnosed at the age of 11.
|
|
Building on data collected as part of the Columbia Presbyterian Hospital chapter of the multi-center Collaborative Perinatal Project, Shaffer led a study of the sequelae of age-7 neurological soft signs. In that study, Shaffer and his colleagues found that neurological soft signs diagnosed at age 7 were related to mood and anxiety disorders ten years later.
|
|
The inflammation may cause a serofibrinous pericardial exudate described as "bread-and-butter" pericarditis, which usually resolves without sequelae. Involvement of the endocardium typically results in fibrinoid necrosis and wart formation along the lines of closure of the left-sided heart valves. Warty projections arise from the deposition, while subendocardial lesions may induce irregular thickenings called MacCallum plaques.
|
|
At 12 months follow-up the cumulative incidence of musculoskeletal adverse events was 3.4%, compared to 1.8% among 893 patients treated with other antibiotics. In the levafloxacin-treated group, approximately two-thirds of these musculoskeletal adverse events occurred in the first 60 days, 86% were mild, 17% were moderate, and all resolved without long-term sequelae.
|
|
Esmat was born on 3 January 1956 in Giza, Egypt. He is professor of Endemic Hepatology and Gastroenterology, Kasr El Ainy Hospital, Faculty of Medicine, Cairo University, Egypt. He is peculiarly specialized in viral hepatitis and all its sequelae as well as the different related and advanced techniques such as abdominal ultrasonography and the different endoscopic modalities.
|
|
The major and usually only clinical response to infection with PPV is maternal reproductive failure. Pathologic sequelae depend mainly on when exposure occurs during gestation. Dams may return to estrus, fail to farrow despite being anestrus, farrow few pigs per litter, or farrow a large proportion of mummified fetuses. All can reflect embryonic or fetal death or both.
|
|
At a median 14 years after tibial nailing of isolated tibial fractures, patients' function is comparable to population norms, but objective and subjective evaluation shows persistent sequelae which are not insignificant. One potential complication of intramedullary nailing after a fracture is bone malrotation, where the broken bone is fixated out of alignment and heals incorrectly, causing a rotated limb.
|
|
Most cases are benign and self-limiting, but lymphadenopathy may persist for several months after other symptoms disappear. The disease usually resolves spontaneously, with or without treatment, in one month. In rare situations, CSD can lead to the development of serious neurologic or cardiac sequelae such as meningoencephalitis, encephalopathy, seizures, or endocarditis. Endocarditis associated with Bartonella infection has a particularly high mortality.
|
|
Studies have indicated that it is important to consider the effect of domestic violence and its psychophysiologic sequelae on women who are mothers of infants and young children. Several studies have shown that maternal interpersonal violence-related posttraumatic stress disorder (PTSD) can, despite a traumatized mother's best efforts, interfere with their child's response to the domestic violence and other traumatic events.
|
|
Lesion is any abnormality in the tissue of an organism (in layman's terms, "damage"), usually caused by disease or trauma. Lesion is derived from the Latin word laesio meaning injury. Similar to the ICD-10 the World Health Organization produces the International Classification of External Causes of Injury (ICECI). Sequelae of resolved diseases sometimes are considered inside lesions and other times inside diseases.
|
|
This implies that the classification is tapping a quality of the relationship, and not merely the child's temperament.van IJzendoorn, M. H., Schuengel, C., & Bakermans-Kranenburg, M. J. (1999). Disorganized attachment in early childhood: Meta-analysis of precursors, concomitants, and sequelae, Development and Psychopathology, 11, 225–249. A classification of disorganized/disoriented attachment has been found to be a risk factor for later development.
|
|
A cameraman is usually near the location of the attack to record the event. Video taped terrorist attacks are distinct from martyrdom videos in they show the action and sequelae, but not the intention. Martyrdom videos are intended to provide justification and reasoning behind the action. IED attacks are likely to be videotaped, as the recording provides evidence of their success.
|
|
Patients with GSD I will often develop osteopenia. The specific etiology of low bone mineral density in GSD is not known, though it is strongly associated with poor metabolic control. Osteopenia may be directly caused by hypoglycemia, or the resulting endocrine and metabolic sequelae. Improvements in metabolic control have consistently been shown to prevent or reverse clinically relevant osteopenia in GSD I patients.
|
|
In rodents, hantavirus produces a chronic infection with no adverse sequelae. In humans, hantavirus produces two major clinical syndromes: hemorrhagic fever or pulmonary syndrome. European, Asian, and African rodent-borne hantaviruses cause hemorrhagic fever. The pulmonary syndrome, caused by the species Sin Nombre orthohantavirus, has not been found anywhere other than the United States where deer mice are the natural hosts.
|
|
The postoperative period begins after the transfer to the Post Anesthesia Care Unit (PACU) and terminates with the resolution of the surgical sequelae. It is quite common for the very last of this period to end outside of the care of the surgical team. It is uncommon to provide extended care past the discharge of the patient from the PACU.
|
|
Encephalitis lethargica. Its sequelae and treatment – Constantin Von Economo, 1931: front page The causes of encephalitis lethargica are uncertain. Some studies have explored its origins in an autoimmune response, and, separately or in relation to an immune response, links to pathologies of infectious disease — viral and bacterial, e.g., in the case of influenza, where a link with encephalitis is clear.
|
|
The incidence is halved in the absence of neuro- muscular blockade. The quoted incidences are controversial as many cases of "awareness" are open to interpretation. The incidence of anesthesia awareness is higher and has more serious sequelae when muscle relaxants or neuromuscular-blocking drugs are used. This is because without relaxant the patient will move and the anesthesiologist will deepen the anesthesia.
|
|
This altered translucency in the tooth is due to disruption and cutting off of the apical neurovascular blood supply. Sequelae of a necrotic pulp include acute apical periodontitis, dental abscess or radicular cyst and discolouration of the tooth. Tests for a necrotic pulp include: vitality testing using a thermal test or an electric pulp tester. Discolouration may be visually obvious, or more subtle.
|
|
Georg Puppe attended the Raths- and Friedrichs-Gymnasium in Kostrzyn nad Odrą, where he graduated in 1884. He then studied medicine in Berlin and Göttingen. In 1887, he became a member of the fraternity Burschenschaft Brunsviga. In 1888, Puppe completed his exams in Berlin and received his doctorate in the same year with the subject: "Investigations on the sequelae after Abortus".
|
|
Snake venom poisoning in the United States: a review of therapeutic practice. Southern Medical Journal 87:579–589. This is largely due to the wide availability of antivenom, although estimates for mortality in the early 1900s ranged from 5-25% for all snake bites in the United States.Dart RC: Sequelae of pit viper envenomation, in Campbell JA, Brodie ED Jr, eds: Biology of the Pit Vipers.
|
|
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring at about a 25 to 40% rate (latest data greater than 80%). It is a viral infection of the nervous system after the initial infection. Symptoms typically occur 15 to 30 years after an initial acute paralytic attack. Symptoms include decreasing muscular function or acute weakness with pain and fatigue.
|
|
Children with chronic giardiasis are at risk for failure to thrive as well as more long-lasting sequelae such as growth stunting. Up to half of infected people develop a temporary lactose intolerance leading symptoms that may mimic a chronic infection. Some people experience post-infectious irritable bowel syndrome after the infection has cleared. Giardiasis has also been implicated in the development of food allergies.
|
|
His mother, Lady Lee Jungbin of Hamseong, was the daughter of Lee Jun-chul, a noble of Joseon. His first name was Man-bok, which was later changed to Haeng. In 1720, King Sukjong died due to dementia and Smallpox sequelae and was succeeded by his son Crown Prince Yi Kyun as King Gyeongjong. As Gyeongjong was childless, Prince Yeoning, Hyojang's father was appointed as Crown Prince.
|
|
In stage III disease, as classified by the Hurley's staging system, fistulae left undiscovered, undiagnosed, or untreated, can rarely lead to the development of squamous cell carcinoma in the anus or other affected areas. Other stage III chronic sequelae may also include anemia, multilocalized infections, amyloidosis, and arthropathy. Stage III complications have been known to lead to sepsis, but clinical data is still uncertain.
|
|
This could lead to a higher degree of neuroprotection. Lack of sleep might increase the levels of extracellular adenosine, which is also mostly neuroprotective against the TBI sequelae. Furthermore, sleep deprivation might lead to a form of “ischemic precondition” which habituates the brain to the byproducts of a cellular injury. Studies have been run to assess the role of caffeine in rats with sleeping disorders.
|
|
Coil embolisation requires exclusion of other pelvic pathology, expertise in endovascular surgery, correct placement of appropriate sized coils in the pelvis and also in the upper left ovarian vein, careful pre- and post-procedure specialist vascular ultrasound imaging, a full discussion of the procedure with the patient i.e. informed consent. Complications, such as coil migration, are rare but reported. Their sequelae are usually minor.
|
|
Recovery was judged moderate in 12% and poor in only 4% of patients. quoted in Another study found that incomplete palsies disappear entirely, nearly always in the course of one month. The patients who regain movement within the first two weeks nearly always remit entirely. When remission does not occur until the third week or later, a significantly greater part of the patients develop sequelae.
|
|
Astrocytoma causes regional effects by compression, invasion, and destruction of brain parenchyma, arterial and venous hypoxia, competition for nutrients, release of metabolic end products (e.g., free radicals, altered electrolytes, neurotransmitters), and release and recruitment of cellular mediators (e.g., cytokines) that disrupt normal parenchymal function. Secondary clinical sequelae may be caused by elevated intracranial pressure attributable to direct mass effect, increased blood volume, or increased cerebrospinal fluid volume.
|
|
There is evidence to show that steroids given to babies less than 8 days old can prevent bronchopulmonary dysplasia. However, the risks of neurodevelopmental sequelae may outweigh the benefits. It is unclear if starting steroids more than 7 days after birth is harmful or beneficial. It is thus recommended that they only be used in those who cannot be taken off of a ventilator.
|
|
Turman faced Andrew Sanchez on August 8, 2020 at UFC Fight Night 174. He lost the fight via knockout in round one. Turman was scheduled to face Sean Strickland on October 31, 2020 at UFC Fight Night 181. However on September 29, Turman pulled out due to COVID-19 sequelae that rendered him unable to train after his two-week quarantine ended on September 24, 2020.
|
|
Since many causes of seizures can be rapidly reversed and longterm sequelae prevented, evaluation of underlying cause is of utmost importance. Evaluation for infection (with blood counts, lumbar puncture, and empiric treatment with antibiotics) often occurs during EEG monitoring. Blood glucose and electrolyte testing can identify metabolic problems that can be corrected. Further testing includes evaluation for genetic causes and other more rare metabolic causes.
|
|
The American Academy of Pediatrics estimates that overall complications occur in from 2.4% to 5% of Plastibell procedures. The risk of bleeding is 1%, similar to the risk with the Gomco clamp and Mogen clamp. A significant complication can occur if the glans swells and herniates (protrudes) through the ring. This worsens the swelling and can reduce blood and urine flow, resulting in serious long-term sequelae.
|
|
An ESR should be drawn to detect possible giant cell arteritis. Improvement can be determined by visual acuity, visual field testing, and by ophthalmoscopic examination. At a later stage, pan-retinal photocoagulation (PRP) with an argon laser appears effective in reducing the neovascular components and their sequelae. The visual prognosis for ocular ischemic syndrome varies from usually poor to fair, depending on speed and effectiveness of the intervention.
|
|
Natalizumab appears to interact with other immune-modulating drugs to increase the risk of progressive multifocal leukoencephalopathy (PML), an often-fatal opportunistic infection caused by the JC virus. In 2005, two people taking natalizumab in combination with interferon beta-1a developed PML. One died, and the other recovered with disabling sequelae. A third fatal case initially attributed to an astrocytoma was reported in a patient being treated for Crohn's disease.
|
|
In addition, lymphatic drainage of lung units appears to be curtailed—stunned by the acute injury—which contributes to the build-up of extravascular fluid. Some patients rapidly recover from ALI and have no permanent sequelae. Prolonged inflammation and destruction of pneumocytes leads to fibroblastic proliferation, hyaline membrane formation, tracheal remodeling and lung fibrosis. This fibrosing alveolitis may become apparent as early as five days after the initial injury.
|
|
Lexikon Psychiatrie, Psychotherapie, Medizinische Psychologie. Dipsomania entry at Google Books. Brühl-Cramer classified dipsomania in terms of continuous, remittent, intermittent, periodic and mixed forms, and in his book he discussed its cause, pathogenesis, sequelae, and treatment options, all influenced by prevailing ideas about the laws of chemistry and concepts of excitability.Wiley.com journal Due to the influence of Brühl-Cramer's pioneering work, dipsomania became popular in medical circles throughout the 19th century.
|
|
It was initially used for uterine extraction, but later applied to other organs. The use of morcellators at surgery has now become commonplace, with at least 5 devices currently on the US market. Despite decades of experience, there remains limited understanding of the short-term and long-term sequelae of morcellation. Concerns have been raised about injury to surrounding organs including bowel, bladder, ureters, pancreas, spleen and major vascular structures.
|
|
This can be evaluated both subjectively, or objectively using a device such as the Cutometer. The Cutometer applies a vacuum to the skin and measures the extent to which it can be vertically distended. These measurements are able to distinguish between healthy skin, normal scarring, and pathological scarring, and the method has been applied within clinical and industrial settings to monitor both pathophysiological sequelae, and the effects of treatments on skin.
|
|
While in the digestive tract, the battery's electrical discharge may lead to tissue damage; such damage is occasionally serious and can lead to death. Ingested disk batteries do not usually cause problems unless they become lodged in the gastrointestinal tract. The most common place for disk batteries to become lodged is the esophagus, resulting in clinical sequelae. Batteries that successfully traverse the esophagus are unlikely to lodge elsewhere.
|
|
The role of SP in HIV-AIDS has been well-documented. Doses of aprepitant greater than those tested to date are required for demonstration of full efficacy. Respiratory syncytial and related viruses appear to upregulate SP receptors, and rat studies suggest that NK1RAs may be useful in treating or limiting long term sequelae from such infections. Entamoeba histolytica is a unicellular parasitic protozoan that infects the lower gastrointestinal tract of humans.
|
|
The horse was admitted to Saint-Cyr in 1936. The captain Philippe Leclerc de Hauteclocque (the future Marshal Leclerc), then instructor at Saint-Cyr, participated in the military training of Iris XVI. Renowned for his difficult character, Iris XVI did not fail to disconcert his riders. Captain Philippe Leclerc de Hauteclocque owed his limp and cane to a fall from Iris XVI's back, resulting in a fractured tibia, with lifelong sequelae.
|
|
She examined over 300 torture victims at the Center. Crosby is one of the authors of Broken Laws, Broken Lives: Medical Evidence of Torture by the US, published by Physicians for Human Rights. According to Physicians for Human Rights Crosby has "written over 200 affidavits documenting medical and psychological sequelae of torture." In October 2009 Crosby submitted an affidavit following her examination of Guantanamo's longest term hunger striker, Abdul Rahman Shalabi.
|
|
Flammer syndrome requires no therapy as long as a person does not suffer from the symptoms or pathological sequelae occur. The treatment is based on three pillars: a) lifestyle interventions, b) diet and c) medication. A healthy lifestyle should include regular sleep, weight stabilization (in the sense of not being underweight), avoiding periods of fasting and avoidance of known trigger factors such as cold. Regular physical exercise is good, extreme sports might be detrimental.
|
|
Similarly, the trigger for episodes of crying in patients with PBA may be nonspecific, minimal or inappropriate to the situation, but in depression the stimulus is specific to the mood-related condition. These differences are outlined in the adjacent Table. In some cases, depressed mood and PBA may co-exist. Since depression is one of the most common emotional changes in patients with neurodegenerative disease or post-stroke sequelae, it is often comorbid with PBA.
|
|
The subacute form causes weakness, fasciculations, cramping, and stiffness of muscles, which can lead to recumbency, as well as a stilted gait, dysphagia, ptyalism, and a weak suckle. It may be treated with selenium supplementation, but there is a 30–45% mortality rate. Other sequelae include aspiration pneumonia, failure of passive transfer, and stunting of growth. Clinical laboratory changes include evidence of rhabdomyolysis (elevated CK and AST, myoglobinuria) and low blood selenium levels.
|
|
Symptoms typically appear gradually over 5 to 20 minutes and generally last less than 60 minutes, leading to the headache in classic migraine with aura, or resolving without consequence in acephalgic migraine. Many migraine sufferers change from scintillating scotoma as a prodrome to migraine to scintillating scotoma without migraine. Typically the scotoma resolves spontaneously within the stated time frame, leaving no subsequent symptoms, though some report fatigue, nausea, and dizziness as sequelae.
|
|
I suspect most doctors, frustrated at bureaucracy and barriers, would disagree. That it has taken a global crisis, which is killing patients and health-care staff, and which will have profound psychological sequelae, to make this happen, is catastrophic, and an unpayable price”. She is a patron of HealthWatch UK, a charity which challenges poor evidence in health reporting, as well as an honorary fellow of the Centre for Evidence-Based Medicine.
|
|
Electroencephalography and transcranial doppler may also be used. The most sensitive physical measure to date is the quantitative EEG, which has documented an 80% to 100% ability in discriminating between normal and traumatic brain-injured subjects. Neuropsychological assessment can be performed to evaluate the long-term cognitive sequelae and to aid in the planning of the rehabilitation. Instruments range from short measures of general mental functioning to complete batteries formed of different domain-specific tests.
|
|
Strickland became a free agent after the fight by fighting out his contract. Returning from a two-year layoff after motorcycle accident, Strickland was scheduled to face Wellington Turman on October 31, 2020 at UFC Fight Night 181. However on September 29, Turman pulled out due to COVID-19 sequelae that rendered him unable to train after his two-week quarantine ended on September 2, and he was replaced by Jack Marshman.
|
|
Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Onset time is 12 to 96 hours, and recovery takes 5 to 7 days. Infections are associated with mucosal ulceration, rectal bleeding, and drastic dehydration. Reactive arthritis and hemolytic uremic syndrome are possible sequelae that have been reported in the aftermath of shigellosis.
|
|
An observational study, done roughly 29 months after the 2007 Bundibugyo outbreak in Uganda, found that long-term sequelae (i.e. consequences) persisted among survivors. Symptoms included eye pain, blurred vision, hearing loss, difficulty swallowing, difficulty sleeping, arthralgias, memory loss or confusion, and "various constitutional symptoms controlling for age and sex". From August through December 2014, a total of 10 patients with Ebola were treated in US hospitals; of these patients, 8 survived.
|
|
Disorders usually resolve after early treatment. If the treatment is delayed, the overall health of the child is improved but physical (reduced) and intellectual (mental disabilities) sequelae are feared. Without treatment or if treatment occurs too late, death is inevitable. A high risk of death is identified by a brachial perimeter < 11 cm or by a weight-to-height threshold < −3 SD. In practice, malnourished children with edema are suffering from potentially life-threatening severe malnutrition.
|
|
All patients with empyema require outpatient follow-up with a repeat chest X-ray and inflammatory biochemistry analysis within 4 weeks following discharge. Chest radiograph returns to normal in the majority of patients by 6 months. Patients should, of course, be advised to return sooner if symptoms redevelop. Long-term sequelae of pleural empyema are rare but include bronchopleural fistula formation, recurrent empyema and pleural thickening, which may lead to functional lung impairment needing surgical decortication.
|
|
Bupivacaine injection is currently the only pharmacologic treatment clinically shown to strengthen and shorten extraocular muscles. Myogenic growth factors (IGF and FGF) have only been tested in animals. Long used as an anesthetic in cataract surgery, bupivacaine was found to sometimes cause strabismus, presumably because it had been inadvertently injected into a muscle. Initially attributed to simple myotoxic damage, careful observation of the clinical time course showed more complex sequelae, including increased contractility and elevated stiffness.
|
|
Timely extractions are often the preferred treatment plan for first permanent molars that are severely affected and symptomatic. The facilitation of eruption of the second permanent molars to the space of the first permanent molar removes the burden of continuous restorative treatment. A favourable occlusion may be acquired following a well-planned treatment and this eliminates the need for fixed orthodontic appliances therapy. However, a comprehensive discussion of the possible need of orthodontic sequelae and treatment is important.
|
|
The tetrahydroisoquinolinium class of neuromuscular blocking agents, in general, is associated with histamine release upon rapid administration of a bolus intravenous injection. There are some exceptions to this rule; e.g., cisatracurium (Nimbex) is one such agent that does not elicit histamine release even up to 5xED95 doses. The liberation of histamine is a dose-dependent phenomenon such that, with increasing doses administered at the same rate, there is a greater propensity for eliciting histamine release and its ensuing sequelae.
|
|
In 2014 Coroian was hired as Metalurgistul Cugir manager and after a promising first season things have taken an unexpected turn. On 22 July 2015, during a training, he suffered a stroke after which he remained sequelae and was forced to withdraw from his football manager career.Cristi Coroian, în stare critică: fostul vârf al CFR-ului şi al Gloriei Bistriţa a suferit un atac cerebral şi este internat la Terapie Intensivă. Prima reacţie a doctorilor. prosport.
|
|
Many lymphoceles are asymptomatic. Larger lymphoceles may cause symptoms related to compression of adjacent structures leading to lower abdominal pain, abdominal fullness, constipation, urinary frequency, and edema of the genitals and/or legs. Serious sequelae could develop and include infection of the lymphocele, obstruction and infection of the urinary tract, intestinal obstruction, venous thrombosis, pulmonary embolism, chylous ascites and lymphatic fistula formation. On clinical examination the skin may be reddened and swollen and a mass felt.
|
|
Powassan virus infection is rarely diagnosed as a cause of encephalitis; however, when it is, Powassan encephalitis is severe, and neurologic sequelae are common. Powassan encephalitis has symptoms compatible with acute disseminated encephalomyelitis, oftentimes making it difficult to diagnose. Powassan virus encephalitis is a challenge to diagnose because there are only a few laboratories that offer testing, the most effective being serologic testing. There are currently no medications or vaccines to treat or prevent the POWV.
|
|
Testosterone deficiency is associated with an increased risk of metabolic syndrome, cardiovascular disease and mortality, which are also sequelae of chronic inflammation. Testosterone plasma concentration inversely correlates to multiple biomarkers of inflammation including CRP, interleukin 1 beta, interleukin 6, TNF alpha and endotoxin concentration, as well as leukocyte count. As demonstrated by a meta-analysis, substitution therapy with testosterone results in a significant reduction of inflammatory markers. These effects are mediated by different mechanisms with synergistic action.
|
|
In addition, he has contributed to understanding the neurological outcomes of survivors of nervous system infections and cancer.Pomeroy SL, Holmes SJ, Dodge PR, Feigin RD. Seizures and other neurologic sequelae of bacterial meningitis in children. N Engl J Med 1990; 323:1651-1657.Lipton J, Megerian JT, Kothare SV, Cho YJ, Shanahan T, Chart H, Ferber R, Adler-Golden L, Cohen LE, Czeisler CA, Pomeroy SL. Melatonin deficiency and disrupted circadian rhythms in pediatric survivors of craniopharyngioma.
|
|
If this happens, parents should be advised of possible complications such as enamel hypoplasia, hypocalcification, crown/root dilaceration, or disruptions in tooth eruption sequence. Potential sequelae can involve pulpal necrosis, pulp obliteration and root resorption. Necrosis is the most common complication and an assessment is generally made based on the colour supplemented with radiograph monitoring. A change in colour may mean that the tooth is still vital but if this persists it is likely to be non-vital.
|
|
All adverse events were managed with minor interventions and resolved without long-term sequelae. Rates were similar to those observed with conventional surgical circumcision. In settings where skilled surgeons are mostly located in urban centers, referral of clients who require surgical management of device-related complications within the recommended time frame of 6–12 hours may not be possible. Healing is by secondary intention and is therefore delayed compared to techniques which allow for healing by primary intention.
|
|
Chorioretinitis is often caused by toxoplasmosis and cytomegalovirus infections (mostly seen in immunodeficient subjects such as people with HIV/AIDS or on immunosuppressant drugs). Congenital toxoplasmosis via transplacental transmission can also lead to sequelae such as chorioretinitis along with hydrocephalus and cerebral calcifications. Other possible causes of chorioretinitis are syphilis, sarcoidosis, tuberculosis, Behcet's disease, onchocerciasis, or West Nile virus. Chorioretinitis may also occur in presumed ocular histoplasmosis syndrome (POHS); despite its name, the relationship of POHS to Histoplasma is controversial.
|
|
Studies have shown that, contrary to adults, children with obstructive sleep-disordered breathing are able to maintain cerebral oxygenation. However, the condition still has effects on the brain and can lead to adverse neurocognitive and behavioral sequelae. It is particularly concerning as those consequences happen while the brain is still developing. The degree to which the sleep is disturbed and fragmented has been significantly linked to the severity of the consequences, the latter having the possibility to decrease once the sleep is improved.
|
|
"Child-on-child sexual abuse: An investigation of behavioral and emotional sequelae," University of Pennsylvania, p. 1539. An increased risk of victimization later in life has also been reported. The term minor sex offenders may be used for children under 18 years old that have initiated any non-consensual sexual activity with another person. This population may be viewed as a younger version of sexual perpetrators and may be assessed as part of a same group, when they represent a significant heterogenous group.
|
|
Neurocardiology is the study of the neurophysiological, neurological and neuroanatomical aspects of cardiology, including especially the neurological origins of cardiac disorders. The effects of stress on the heart are studied in terms of the heart's interactions with both the peripheral nervous system and the central nervous system. Clinical issues in neurocardiology include hypoxic-ischemic brain injury, neurogenic stress cardiomyopathy, cerebral embolism, encephalopathy, neurologic sequelae of cardiac and thoracic surgery and cardiac interventions, and cardiovascular findings in patients with primary neurological disease.
|
|
In the first case, emergency surgery did not locate any hernia but found the round ligament of the uterus to be edematous and filled with thrombosed varicose veins. The thrombosed part was excised and the patient recovered without sequelae. Another case report described a 37-year- old woman presenting with inguinal mass 6 days after normal vaginal delivery. CT and MRI revealed thrombosed blood vessels along the inguinal course of the uterine round ligament that extended towards the labia majora.
|
|
He enlisted in the First AIF on 18 August 1914, and he served overseas in the 7th Australian Infantry Battalion. He sustained gunshot wounds to his left thigh and leg, on active service, that immediately required three operations; and, as well, he received treatment for the wounds' sequelae on several occasions post-war. Although Evans had been allocated a block of land under the "Soldier Settlement Scheme", his service record shows that he surrendered the block in the second half of 1933.
|
|
Most commonly, the histamine release following administration of these agents is associated with observable cutaneous flushing (facial face and arms, commonly), hypotension and a consequent reflex tachycardia. These sequelae are very transient effects: The total duration of the cardiovascular effects is no more than one to two minutes, while the facial flush may take around 3–4 minutes to dissipate. Because these effects are so transient, there is no reason to administer adjunctive therapy to ameliorate either the cutaneous or the cardiovascular effects.
|
|
It takes 5 to 15 days after the bite of an infected mosquito to develop symptoms of LACV disease. Symptoms include nausea, headache, vomiting in milder cases and seizures, coma, paralysis and permanent brain damage in severe cases. LAC encephalitis initially presents as a nonspecific summertime illness with fever, headache, nausea, vomiting and lethargy. Severe disease occurs most commonly in children under the age of 16 and is characterized by seizures, coma, paralysis, and a variety of neurological sequelae after recovery.
|
|
In lipidomics, the process of shotgun lipidomics (named by analogy with shotgun sequencing) uses analytical chemistry to investigate the biological function, significance, and sequelae of alterations in lipids and protein constituents mediating lipid metabolism, trafficking, or biological function in cells. Lipidomics has been greatly facilitated by recent advances in, and novel applications of, electrospray ionization mass spectrometry (ESI/MS). Lipidomics is a research field that studies the pathways and networks of cellular lipids in biological systems (i.e., lipidomes) on a large scale.
|
|
Several consequent reports from China on some recovered SARS patients showed severe long-time sequelae. The most typical diseases include, among other things, pulmonary fibrosis, osteoporosis, and femoral necrosis, which have led in some cases to the complete loss of working ability or even self-care ability of people who have recovered from SARS. As a result of quarantine procedures, some of the post-SARS patients have been documented as suffering from post-traumatic stress disorder (PTSD) and major depressive disorder.
|
|
He also submitted a medical report from a doctor that opined that his condition was "[r]ight shoulder pain, most likely sequelae of his dislocation of the shoulder." Lastly, he submitted medical reports showing a history of a right shoulder dislocation and pain. The VA Regional Office denied the claim, citing that there was no evidence of continuity of symptomatology since service. The Board of Veterans' Appeals upheld the denial, reasoning that the report from his doctor simply transcribed Jandreau's own lay history.
|
|
It is not advisable to use mineral water in the form of a cleanse without medical indication. In the internal cure (through the direct consumption of mineral water), the springs in Borsec are indicated: • In diseases of the digestive tract and the adjacent glands: chronic hypo- or normoacid gastritis, dyspepsia, mild enteritis, enterocolitis, fermentation colitis. • In chronic hepatitis, posthepatitis states, biliary disorders, sequelae after on the bile ducts surgery. • In nutrition diseases: compensated and balanced diabetes mellitus type 2, gout and uterine diathesis.
|
|
Reactogenicity describes the immediate short-term reactions of a system to vaccines and should not be confused with the long-term consequences sequelae. Assessments of reactogenicity are carried out to evaluate the safety and usability of an experimental vaccine (see Investigational New Drug). It is unclear whether a higher degree of reactogenicity to a vaccine correlates with more severe adverse events, which would require hospitalization or are life- threatening. Adverse events have been linked to a higher degree of reactogenicity; however, the links might have been coincidental.
|
|
Neurocognitive symptoms, such as fatigue, mood disturbances, and other related symptoms are common sequelae. Even in those who have made good neurological recovery, anxiety, depression, posttraumatic stress disorder, and cognitive impairment are common; 46 percent of people who have had a subarachnoid hemorrhage have cognitive impairment that affects their quality of life. Over 60 percent report frequent headaches. Aneurysmal subarachnoid hemorrhage may lead to damage of the hypothalamus and the pituitary gland, two areas of the brain that play a central role in hormonal regulation and production.
|
|
Complications may also arise as a result of various treatments. The development of complications depends on a number of factors, including the degree of vulnerability, susceptibility, age, health status, and immune system condition. Knowledge of the most common and severe complications of a disease, procedure, or treatment allow for prevention and preparation for treatment if they should occur. Complications are not to be confused with sequelae, which are residual effects that occur after the acute (initial, most severe) phase of an illness or injury.
|
|
The main activity of activation of the insulin receptor is inducing glucose uptake. For this reason "insulin insensitivity", or a decrease in insulin receptor signaling, leads to diabetes mellitus type 2 – the cells are unable to take up glucose, and the result is hyperglycemia (an increase in circulating glucose), and all the sequelae that result from diabetes. Patients with insulin resistance may display acanthosis nigricans. A few patients with homozygous mutations in the INSR gene have been described, which causes Donohue syndrome or Leprechaunism.
|
|
Bautista receives surgery for the gunshot wound received, and finally manages to save his life and recovered without sequelae of magnitude. After his escape, Montserrat goes into hiding in the company of Unquillo. Meanwhile, Rosario keeps track of Juliana at the company of the Unquillo, and to spy on the activities of the former manages to be hired as a maintenance worker. During the time she remains in the company discovers that the Unquillo stores the bulk of the monetary proceeds of the Network.
|
|
A meta-analysis of 4 samples involving 223 children found a significant association between disorganization and school age controlling attachment behavior.van IJzendoorn, M. H., Schuengel, C., & Bakermans-Kranenburg, M. J. (1999). Disorganized attachment in early childhood: Meta-analysis of precursors, concomitants, and sequelae, Development and Psychopathology, 11(2), 225–249. Main conceptualised disorganization/disorientation as representing some form of contradiction or disruption of the attachment system: either a conflict between simultaneous dispositions to physically approach and to flee the caregiver, or seeming disorientation to the environment.
|
|
Cullen contracted polio in August 1921, when he was 18 months old. The long-term sequelae of that illness, combined with injuries sustained in a serious motor vehicle accident in 1937 requiring a nine-month hospitalization, made it difficult for him to walk or stand for an extended period of time.Cox, Jim (2007). Radio Speakers: Narrators, News Junkies, Sports Jockeys, Tattletales, Tipsters, Toastmasters and Coffee Klatch Couples Who Verbalized the Jargon of the Aural Ether from the 1920s to the 1980s--A Biographical Dictionary.
|
|
New Mobility was founded in 1989 in Boulder, Colorado, by Sam Maddox to provide information about life after spinal cord injury, multiple sclerosis, post-polio sequelae and other disabling conditions. Originally titled, Spinal Network Extra, the then-quarterly magazine was a spin-off of the 1987 book Spinal Network: The Total Resource for the Wheelchair Community. Maddox edited New Mobility until 1991, when Barry Corbet, a paraplegic from a spinal cord injury, took the helm. The title was changed to New Mobility for the Summer 1992 issue.
|
|
Apexification is a method of dental treatment to induce a calcific barrier in a root with incomplete formation or open apex of a tooth with necrotic pulp. Pulpal involvement usually occurs as a consequence of trauma or caries involvement of young or immature permanent teeth. As a sequelae of untreated pulp involvement, loss of pulp vitality or necrotic pulp took place for the involved teeth. The main purpose of apexification includes restoring the original physiologic structures and functions of the pulp-dentin complex of the teeth.
|
|
The prognosis is typically good when medical care is provided and patients adequately treated are unlikely to have any long-term sequelae. However, severely affected patients with prolonged seizures or respiratory failure may have ongoing impairments secondary to the hypoxia. It has been stated that if a patient survives nicotine poisoning during the first 4 hours, they usually recover completely. At least at "normal" levels, as nicotine in the human body is broken down, it has an approximate biological half-life of 1–2 hours.
|
|
CT scan showing epidural hematoma (arrow) Diagnosis is suspected based on lesion circumstances and clinical evidence, most prominently a neurological examination, for example checking whether the pupils constrict normally in response to light and assigning a Glasgow Coma Score. Neuroimaging helps in determining the diagnosis and prognosis and in deciding what treatments to give. DSM-5 can be utilized to diagnose TBI and its psychiatric sequelae. The preferred radiologic test in the emergency setting is computed tomography (CT): it is quick, accurate, and widely available.
|
|
Not all sequelae of trauma are immediate and many of them can occur months or years after the initial incident thus required prolonged follow-up. Common complications are pulpal necrosis, pulpal obliteration, root resorption and damage to the successors teeth in primary teeth dental trauma. The most common complication was pulp necrosis (34.2%). 50% of the tooth that have trauma related to avulsion experienced ankylotic root resorption after a median TIC (time elapsed between the traumatic event and the diagnosis of complications) of 1.18 years.
|
|
Like other "in situ" devices, complications may occur up to several days following the placement procedure and must be dealt with promptly to prevent serious sequelae. Shang Ring should only be used where surgical care is rapidly available. In a review by WHO personnel, 0.4% men required rapid intervention with surgical circumcision as the excision had occurred but the foreskin slipped from the device and required suturing. No serious adverse events occurred; 1% experienced moderate adverse events from a total of 1983 successful device placements.
|
|
When an infant is born with an anorectal malformation, it is usually detected quickly as it is a very obvious defect. Doctors will then determine the type of birth defect the child was born with and whether or not there are any associated malformations. It is important to determine the presence of any associated defects during the newborn period in order to treat them early and avoid further sequelae. There are two main categories of anorectal malformations: those that require a protective colostomy and those that do not.
|
|
There have been no long-term sequelae of the known adverse events (local or systemic reactions) and no pattern of frequently reported serious adverse events for AVA. The approved FDA package insert for AVA contains the following notice: "The most common (>10%) local (injection- site) adverse reactions observed in clinical studies were tenderness, pain, erythema and arm motion limitation. The most common (>5%) systemic adverse reactions were muscle aches, fatigue and headache." Also, "Serious allergic reactions, including anaphylactic shock, have been observed during post- marketing surveillance in individuals receiving BioThrax".
|
|
HIV infection may lead to a variety of neuropsychiatric sequelae, either by infection of the now susceptible nervous system by organisms, or as a direct consequence of the illness itself. Toxoplasmosis is a disease caused by the single-celled parasite called Toxoplasma gondii; it usually infects the brain, causing toxoplasma encephalitis, but it can also infect and cause disease in the eyes and lungs. Cryptococcal meningitis is an infection of the meninx (the membrane covering the brain and spinal cord) by the fungus Cryptococcus neoformans. It can cause fevers, headache, fatigue, nausea, and vomiting.
|
|
The DDZ performs research on diabetes mellitus in a transdisciplinary approach. The aim is the prevention, early detection, diagnosis and treatment of diabetes and its sequelae. The work focuses on application-oriented research in the fields of clinical diabetology, clinical biochemistry and pathobiochemistry, biometrics and epidemiology, vascular and islet cell biology as well as health services research and health economics. The investigation of risk genes, mechanisms, individual lifestyles in combination with environmental influences and their long-term effects on the population and their supply play a decisive role.
|
|
DDZ has also performed clinical studies and established several cohorts, such as the German Diabetes Study (GDS), which examines the course of diabetes as well as its sequelae. Since 2008, Michael Roden is the chief scientific officer and spokesman of the board of the DDZ as well as the director of the Institute for Clinical Diabetology. Additionally, he serves as the chief physician of the Division of Endocrinology and Diabetology at the University Hospital Düsseldorf. The research center is under the legal body of Association of the German Diabetes Research Association (Deutsche Diabetes-Forschungsgesellschaft e.
|
|
"Currently, there are active attempts to convince the public and women considering abortion that abortion frequently has negative psychiatric consequences. This assertion is not borne out by the literature: the vast majority of women tolerate abortion without psychiatric sequelae." Some U.S. state legislatures have mandated that patients be told that abortion increases their risk of depression and suicide, despite the fact that such risks are not supported by the bulk of the scientific literature, and are contradicted by mainstream organizations of mental-health professionals such as the American Psychological Association.
|
|
In the western world, GBS (in the absence of effective prevention measures) is the major cause of several bacterial infections of the newborn neonatal infection sepsis, pneumonia, and meningitis, which can lead to death or long-term sequelae. GBS neonatal infection typically originates in the lower reproductive tract of infected mothers. GBS infections in newborns are separated into two clinical syndromes, early-onset disease (EOD) and late- onset disease (LOD). EOD manifests from 0 to 7 living days in the newborn, most of the cases of EOD being apparent within 24h of birth.
|
|
Both the variation and mechanism of pain in CPSP have made it difficult to treat. Several strategies have been employed by physicians, including intravenous lidocaine, opioids/narcotics, anti-depressants, anti-epileptic medications and neurosurgical procedures with varying success. Higher rates of successful pain control in persons with CPSP can be achieved by treating other sequelae of stroke, such as depression and spasticity. As the age of the population increases, the diagnosis and management of CPSP will become increasingly important to improve the quality of life of an increasing number of stroke survivors.
|
|
In neurology, the word "dyscopia" is used to describe a condition which is common as one of the sequelae of cerebral commisurotomy, a neurosurgical procedure in which the left and right hemispheres of the brain are separated by severing the corpus callosum. This procedure has been shown to reduce the frequency and severity of seizures in extreme cases of epilepsy. An affected individual will exhibit difficulty with copying simple line drawings. This is often accompanied to lesser or greater degree by difficulty with writing and other fine motor skills.
|
|
While commonly self-limiting, treatment with antibiotics may hasten resolution of symptoms. Diphtheria, a once common childhood respiratory infection, produces a neurotoxin which can result in a biphasic neuropathy. This neuropathy begins with paralysis and numbness of the soft palate and pharynx as well as bulbar weakness several days to weeks after the initial upper respiratory infection, followed by an ascending flaccid paralysis caused by an acute inflammatory demyelinating neuropathy after several more weeks. While antibiotics are effective at eradicating the bacterium, neurological sequelae of infection must be treated with diptheria antitoxin.
|
|
The hyperkinetic form manifested itself with restlessness, motor disturbances as twitching of muscle groups, involuntary movements, anxious mental state and insomnia or inversion of sleep patterns. The amyostatic-akinetic form often led to a chronic state similar to Parkinson's disease, called postencephalitic parkinsonism. The symptoms were weakness of muscles, rigidity of movements and insomnia or sleep inversion. Von Economo published his findings in an article of 1917, "Die Encephalitis lethargica," and in the monograph "Die Encephalitis lethargica, ihre Nachkrankheiten und ihre Behandlung" in 1929 (Encephalitis lethargica – Its sequelae and treatment).
|
|
Readiness for enhanced therapeutic regimen management is a NANDA approved nursing diagnosis which is defined as "A pattern of regulating and integrating into daily living a program(s) for treatment of illness and its sequelae that is sufficient for meeting health-related goals and can be strengthened."NANDA It was introduced at the 15th NANDA conference in 2002. Purpose: This book is devoted to a discussion of nursing diagnoses, outcomes, and interventions for older persons. As such, the diagnoses selected for the volume are not exhaustive, but represent a severely underdeveloped knowledge base.
|
|
Some overlap also occurs with other specialties, varying from country to country and even within a local geographic area. Acute head trauma is most often treated by neurosurgeons, whereas sequelae of head trauma may be treated by neurologists or specialists in rehabilitation medicine. Although stroke cases have been traditionally managed by internal medicine or hospitalists, the emergence of vascular neurology and interventional neuroradiology has created a demand for stroke specialists. The establishment of Joint Commission-certified stroke centers has increased the role of neurologists in stroke care in many primary, as well as tertiary, hospitals.
|
|
Prognosis is generally poor. If a patient survives, recovery may be prompt and complete, or protracted with sequelae, such as orchitis, hepatitis, uveitis, parotitis, desquamation or alopecia. Importantly, MARV is known to be able to persist in some survivors and to either reactivate and cause a secondary bout of MVD or to be transmitted via sperm, causing secondary cases of infection and disease. Of the 252 people who contracted Marburg during the 2004–2005 outbreak of a particularly virulent serotype in Angola, 227 died, for a case fatality rate of 90%.
|
|
Symptomatic treatment, supportive care, or supportive therapy is any medical therapy of a disease that only affects its symptoms, not the underlying cause. It is usually aimed at reducing the signs and symptoms for the comfort and well-being of the patient, but it also may be useful in reducing organic consequences and sequelae of these signs and symptoms of the disease. In many diseases, even in those whose etiologies are known (e.g., most viral diseases, such as influenza and Rift Valley fever), symptomatic treatment is the only treatment available so far.
|
|
Ablative fractional resurfacing may be considered for textural skin changes. Hemangiomas, especially those that have gotten very large during the growth phase, may leave behind stretched skin or fibrofatty tissue that may be disfiguring or require future surgical correction. Areas of prior ulceration may leave behind permanent scarring. Additional long-term sequelae stem from the identification of extracutaneous manifestations in association with the IH. For example, a patient with a large facial hemangioma who is found to meet criteria for PHACE syndrome will require potentially ongoing neurologic, cardiac, and/or ophthalmologic monitoring.
|
|
When a reduction in blood flow lasting seconds occurs, the brain tissue suffers ischemia, or inadequate blood supply. If the interruption of blood flow is not restored in minutes, the tissue suffers infarction followed by tissue death. When the low cerebral blood flow persists for a longer duration, this may develop into an infarction in the border zones (areas of poor blood flow between the major cerebral artery distributions). In more severe instances, global hypoxia- ischemia causes widespread brain injury leading to a severe cognitive sequelae called hypoxic-ischemic encephalopathy.
|
|
Prostituted children are at a high risk of catching many infectious diseases and sequelae, and they are at higher risk of contracting HIV. According to a study, it has been found that 17% of brothels in Thailand contain individuals and child prostitutes infected with HIV. In addition, prostituted children who have an STD that causes genital ulcers such as syphilis or chancroid are four times more likely to develop an HIV infection. Lack of medical services for children with STDs can increase this risk since they will remain untreated or will self-medicate.
|
|
A result of between 3–5 seconds is equivocal, whereas the radial artery will not be considered for grafting if the result is longer than 5 seconds. The utility of the modified Allen's test is questionable, and no direct correlation with reduced ischemic complications of radial artery cannulation have ever been proven. In 1983, Slogoff and colleagues reviewed 1,782 radial artery cannulations and found that 25% of them resulted in complete radial artery occlusion, without apparent adverse effects. A number of reports have been published in which permanent ischemic sequelae occurred even in the presence of a normal Allen's test.
|
|
Medical professionals and pro-choice advocates have argued that the effort to popularize the idea of a "post-abortion syndrome" is a tactic used by anti-abortion advocates for political purposes. "Currently, there are active attempts to convince the public and women considering abortion that abortion frequently has negative psychiatric consequences. This assertion is not borne out by the literature: the vast majority of women tolerate abortion without psychiatric sequelae." Some U.S. state legislatures have mandated that patients be told that abortion increases their risk of depression and suicide, despite the scientific evidence contradicting such claims.
|
|
Genie was born about five years after her brother, around the time that her father began to isolate himself and his family from all other people. At birth, she was in the 50th percentile for weight. The following day she showed signs of Rh incompatibility and required a blood transfusion, but had no sequelae and was otherwise described as healthy. A medical appointment at three months showed that she was gaining weight normally but found a congenital hip dislocation, which required her to wear a highly restrictive Frejka splint from the age of to 11 months.
|
|
Such behavior may contribute to cycles of familial violence and trauma. Symptoms of dissociation resulting from trauma may include depersonalization, psychological numbing, disengagement, or amnesia regarding the events of the abuse. It has been hypothesized that dissociation may provide a temporarily effective defense mechanism in cases of severe trauma; however, in the long term, dissociation is associated with decreased psychological functioning and adjustment. Other symptoms sometimes found along with dissociation in victims of traumatic abuse (often referred to as "sequelae to abuse") include anxiety, PTSD, low self- esteem, somatization, depression, chronic pain, interpersonal dysfunction, substance abuse, self-harm and suicidal ideation or actions.
|
|
Appetite may decrease significantly. Though unpleasant, most cases of TD are mild, and resolve in a few days without medical intervention. Blood or mucus in the diarrhea, significant abdominal pain, or high fever suggests a more serious cause, such as cholera, characterized by a rapid onset of weakness and torrents of watery diarrhea with flecks of mucus (described as "rice water" stools). Medical care should be sought in such cases; dehydration is a serious consequence of cholera, and may trigger serious sequelae—including, in rare instances, death—as rapidly as 24 hours after onset if not addressed promptly.
|
|
As with tattoos, permanent makeup may have complications, such as migration, allergies to the pigments, formation of scars, granulomas and keloids, skin cracking, peeling, blistering and local infection. The use of unsterilized tattooing instruments may infect the patient with serious diseases such as HIV and hepatitis. Removal problems may also ensue, due to patient dissatisfaction or regret, and they may be particularly difficult to remove in places such as eyelids and lips without leaving permanent sequelae. Compliance with 'standard precautions' and a uniform code of safe practice should be insisted upon by a person considering undergoing a cosmetic tattoo procedure.
|
|
It has been postulated that van Gogh may have exhibited a form of digoxin toxicity from the foxglove plants used to treat his epilepsy. His yellow period ('yellow vision'), missing ear ('oto-toxicity') and penchant for painting halos around landscape objects ('halo vision') are often used by medical students as a mnemonic to remember the sequelae of digoxin toxicity. Speculation has been further fueled by Van Gogh's portrait of his physician, Dr. Paul-Ferdinand Gachet (1890), in which Gachet holds Digitalis purpurea. But van Gogh was not treated with digitalis, and Dr. Arnold dismisses the plant as a cause of xanthopsia (yellow halos).
|
|
A 2007 review article states that while excessive sodium consumption has long been recognized as contributing to the risk of hypertension, "potassium, the main intracellular cation, has usually been viewed as a minor factor in the pathogenesis of hypertension. However, abundant evidence indicates that a potassium deficit has a critical role in hypertension and its cardiovascular sequelae." The authors state that modern, western, high sodium, low potassium diets result in corresponding changes in intracellular concentration of these, the two most important cations in animal cells. This imbalance leads to contraction of vascular smooth muscle, restricting blood flow and so driving up blood pressure.
|
|
One study found a relapse rate of 56% during an observation period of up to 19 months. Relapses are more frequent in adults than in children. While these lesions usually resolve without sequelae, they may result in skin atrophy and hyperpigmentation. Individuals afflicted with eosinophilic cellulities may have a history of other diseases including various eosinophlic skin diseases, abnormally high levels of circulating blood eosinophils, the hypereosinophilic syndrome, the Churg‐Strauss syndrome, ulcerative colitis, arthralgias, myalgias, facial nerve paralysis, photosensitivity, polycythemia vera, chronic myeloid leukemia, chronic lymphocytic leukemia, Hodgkin lymphoma, nasopharyngeal cancer, and renal cell carcinoma.
|
|
Many psychoanalysts who work with children have studied the actual effects of child abuse, which include ego and object relations deficits and severe neurotic conflicts. Much research has been done on these types of trauma in childhood, and the adult sequelae of those. In studying the childhood factors that start neurotic symptom development, Freud found a constellation of factors that, for literary reasons, he termed the Oedipus complex, based on the play by Sophocles, Oedipus Rex, in which the protagonist unwittingly kills his father and marries his mother. The validity of the Oedipus complex is now widely disputed and rejected.
|
|
Bird led the MRC Biostatistical Initiative in support of AIDS/HIV studies in Scotland (1990–1995), which included projection of Scotland's cases of severe immunodeficiency (so-called CD200 cases) and HIV epidemiological studies in prisons, both with co-investigator, clinical immunologist Dr A. Graham Bird. Bird's work at the interface of public health and other jurisdictions continued. A series of record-linkage studies in Scotland on the late sequelae of Hepatitis C virus infection (with Hutchinson and Goldberg) and on the high risk of drugs-related death soon after prison-release (or after hospital- discharge for drug-treatment clients) followed.
|
|
Researchers from the National Institute of Neurological Disorders and Stroke (NINDS) and Liberian research partners are doing a 5-year follow-up study of 1500 Ebola survivors in Liberia. Survivors will be evaluated every 6 months; as of October 2017 two follow-ups have been performed. Researchers will track relapses and viral persistence, characterize sequelae in various bodily systems, and do clinical studies on pharmacologic interventions and vaccines. PREVAIL III (Partnership for Research on Ebola Vaccines in Liberia III), a study of survivors and their contacts, a collaboration between NINDS and Liberia, was planned in late 2014.
|
|
The model also proposes a developmental component of bipolar disorder, wherein limbic abnormalities are present early on, but rostral prefrontal abnormalities develop later in the course. The importance of limbic dysfunction early in development is highlighted by the observation that amygdala lesions early in adulthood produce emotional abnormalities that are not present in people who develop amygdala damage in adulthood. Lateralized seizure sequelae similar to bipolar has been reported in people with mesial temporal lobe seizures, and provides support for kindling hypotheses about bipolar. This observation led to the first experiments with anticonvulsants in bipolar, which are effective in stabilizing mood.
|
|
Microincisional glaucoma surgery [3, 4] is conducted in a space that is approximately 200 times smaller than the space used to implant epibulbar glaucoma drainage devices [5] As such, this type of surgery is particularly challenging to learn. The deep venous plexus distal to the outer wall of Schlemm's canal, the iris root, the ciliary body band and the suprachoroidal space all risk being damaged during surgery. This damage can cause variable sequelae [6, 7]. To master this surgery, it is important to be able to visualize the angle, identify the correct target, avoid trauma and maximize meshwork removal.
|
|
The strains of group A streptococcus that cause scarlet fever need specific bacteriophages in order for there to be pyrogenic exotoxin production. Specifically, bacteriophage T12 is responsible for the production of speA. Streptococcal Pyrogenic Exotoxin A, speA, is the one which is most commonly associated with cases of scarlet fever which are complicated by the immune-mediated sequelae acute rheumatic fever and post-streptococcal glomerulonephritis. These toxins are also known as “superantigens” because they are able to cause an extensive immune response within the body through activation of some of the main cells responsible for the person's immune system.
|
|
In 1950, he was brutally beaten in the streets by police with a handgun and a rifle. He suffered the sequelae of that incident for years afterwards. He got out of jail in 1952, thanks to the national and international solidarity and the negotiations of his family, which played an essential role in attempts to free prisoners every time Ananías was in jail. Instead of leaving the country, which would have brought a certain amount of security that was not available to him in Paraguay, Ananías fought once again against the dictatorship, from inside the regime, living clandestinely.
|
|
In one in about seventy concussions, concussive convulsions occur, but seizures that take place during or immediately after a concussion are not "post-traumatic seizures", and, unlike post-traumatic seizures, are not predictive of post- traumatic epilepsy, which requires some form of structural brain damage, not just a momentary disruption in normal brain functioning. Concussive convulsions are thought to result from temporary loss or inhibition of motor function and are not associated either with epilepsy or with more serious structural damage. They are not associated with any particular sequelae and have the same high rate of favorable outcomes as concussions without convulsions.
|
|
The transverse rectus abdominis myocutaneous (TRAM) flap method results in weakness and loss of flexibility in the abdominal wall. Reconstruction with implants have a higher risk of long-term pain. Outcomes-based research on quality of life improvements and psychosocial benefits associated with breast reconstruction served as the stimulus in the United States for the 1998 Women's Health and Cancer Rights Act, which mandated that health care payer cover breast and nipple reconstruction, contralateral procedures to achieve symmetry, and treatment for the sequelae of mastectomy. This was followed in 2001 by additional legislation imposing penalties on noncompliant insurers.
|
|
This toxic waste is especially hazardous to those still suffering the effects of direct exposure to the gas. As of 2007, the prospects for learning the sequelae of this disaster do not appear to be bright. What is sorely needed is an independent body to coordinate the health care, research, rehabilitation of gas victims, and care for potential effects in their offspring. Instead of the non- directive symptomatic medical treatment that currently exists, clear guidelines and criteria need to be formulated for specific medical conditions such as damage to bronchial tubes, sleep apnea, neuron destruction, etc.
|
|
The focus here is on eosinophilic myocarditis as a distinct disorder separate from its thrombotic and fibrotic sequelae. Eosinophilic myocarditis is a rare disorder. It is usually associated with, and considered secondary to, an underlying cause for the pathological behavior of the eosinophils such a toxic reaction to a drug (one of its more common causes in developed nations), the consequence of certain types of parasite and protozoan infections (a more common cause of the disorder in areas with these infestations), or the result of excessively high levels of activated blood eosinophils due to a wide range of other causes. The specific treatment (i.e.
|
|
Bornstein is chief of the medical clinic and policlinic III (Medizinische Klinik und Poliklinik III) at the university hospital Carl Gustav Carus in Dresden, which is a major centre of treatment and research of diabetes mellitus type I and type II in Europe as well as its sequelae, like the diabetic foot syndrome, heart and blood vessel diseases and diabetic nephropathy. A major topic is creating individual treatment strategies to prevent the increase in diabetes prevalence. That is why in 2009 they created the first professorship for diabetes prevention in Germany. In 2008 started the only currently active program of islet transplantation in Germany.
|
|
In 1980, Zumla moved to London to pursue an MSc in tropical medicine at the University of London. In 1982, he contracted life-threatening tuberculous meningitis, and was told that he would never walk again, but went on to make a remarkable recovery and return to work a year and a half later to a star-studded career despite disabling and painful neurological sequelae resulting from his meningitis. He went on to pursue doctoral studies on leprosy human monoclonal antibodies at the London School of Hygiene & Tropical Medicine, where his 1987 dissertation (advised by Keith McAdam) merited him the Alan Woodruff Medal.. See library record here.
|
|
Between 25 percent and 50 percent of individuals who have recovered from paralytic polio in childhood can develop additional symptoms decades after recovering from the acute infection, notably new muscle weakness and extreme fatigue. This condition is known as post-polio syndrome (PPS) or post-polio sequelae. The symptoms of PPS are thought to involve a failure of the oversized motor units created during the recovery phase of the paralytic disease. Contributing factors that increase the risk of PPS include aging with loss of neuron units, the presence of a permanent residual impairment after recovery from the acute illness, and both overuse and disuse of neurons.
|
|
Although the symptoms of OMS are typically steroid-responsive and recovery from acute symptoms of OMS can be quite good, children often suffer lifelong neurologic sequelae that impair motor, cognitive, language, and behavioral development. Most children will experience a relapsing form of OMS, though a minority will have a monophasic course and may be more likely to recover without residual deficits. Viral infection may play a role in the reactivation of disease in some patients who had previously experienced remission, possibly by expanding the memory B cell population. Studies have generally asserted that 70-80% of children with OMS will have long-term neurologic, cognitive, behavioral, developmental, and academic impairment.
|
|
The vast majority of the tumors of the heart have a benign course and are not directly fatal. However, even the benign tumors of the heart can be lethal due to either direct extension into the electrical conduction system of the heart (causing complete heart block or a fatal dysrhythmia), or due to emboli from the tumor mass that may have lethal sequelae. The malignant tumors of the heart have a worse prognosis. Cardiac sarcomas generally lead to death within 2 years of diagnosis, due to rapid infiltration of the myocardium of the heart and obstruction of the normal flow of blood within the heart.
|
|
PPV should be considered in a differential diagnosis of reproductive failure of swine whenever there is evidence of embryonic or fetal death or both. The pathologic sequelae of maternal infection during gestation have been described (see the section on clinical signs). If gilts but not sows are affected, maternal illness is not seen during gestation, there are few or no abortions or fetal developmental anomalies, and other evidence suggests an infectious disease, then a tentative diagnosis of PPV-induced reproductive failure can be made. The relative lack of maternal illness, abortions, and fetal developmental anomalies differentiates PPV from most other infectious causes of reproductive failure.
|
|
BAE is effective for hemoptysis in most underlying diseases such as bronchiectasis, nontuberculous mycobacterial disease (NTM), cryptogenic hemoptysis, pulmonary aspergillosis, and pulmonary tuberculosis sequelae. According to Ishikawa who reported long- term treatment results of BAE for 489 hemoptysis patients, each underlying disease's ratio is 34.0%, 23.5%, 18.4%, 13.3%, 6.8%, respectively. Other diseases for which BAE is effective include lung abscess and pulmonary actinomycosis. As for lung cancer, hemoptysis is caused mostly by bleeding from the tumor itself, and not by the bronchial-pulmonary artery shunt mechanism; embolism of the feeding vessels for the tumor causes necrosis of the cancer which may evoke massive hemoptysis.
|
|
It is now well known that persistent and chronic gas-related health effects are present in the Bhopal population. However, the full spectrum of effects is yet to be defined, especially in those exposed as children or in utero, and as manifested in survivor reproductive health. There has been a lack of systematic collection of relevant information in these reproductive effects, and also with respect to cancer development or other chronic illnesses as sequelae of the gas exposure. Recent investigations have shown that local well water has become contaminated by the improper storage of a large amount of hazardous waste in the facility, or on its grounds.
|
|
Oral and intravenous ofloxacin are not licensed for use in children, except as noted above, due to the risk of musculoskeletal injury. In one study, 1534 juvenile patients (age 6 months to 16 years) treated with levofloxacin as part of three efficacy trials were followed up to assess all musculoskeletal events occurring up to 12 months after treatment. At 12 months' follow-up, the cumulative incidence of musculoskeletal adverse events was 3.4%, compared to 1.8% among 893 patients treated with other antibiotics. In the levafloxacin- treated group, about two-thirds of these musculoskeletal adverse events occurred in the first 60 days, 86% were mild, 17% were moderate, and all resolved without long-term sequelae.
|
|
Sroufe, L. A., Carlson, E. A., Levy, A. K., & Egeland, B. (1999). Implications of attachment theory for developmental psychopathology, Development and Psychopathology, 11, 1–13. For example, this classification in infancy has been found associated with school- age externalising problem behavior,van IJzendoorn, M. H., Schuengel, C., & Bakermans-Kranenburg, M. J. (1999). Disorganized attachment in early childhood: Meta-analysis of precursors, concomitants, and sequelae, Development and Psychopathology, 11(2), 225–249; Fearon, R. P., Bakermans- Kranenburg, M. J., van IJzendoorn, M. H., Lapsley, A., & Roisman, G. I. (2010). The significance of insecure attachment and disorganization in the development of children's externalizing behavior: A meta-analytic study, Child Development, 81(2), 435–456.
|
|
The antibody coated fetal red blood cells are destroyed. The resulting anemia has multiple sequelae: (1) The immature hematopoietic system of the fetus is taxed as the liver and spleen attempt to put immature RBCs into circulation (erythroblasts, thus the previous name for this disease erythroblastosis fetalis). (2) As the liver and spleen enlarge under this unexpected demand for RBCs, a condition called portal hypertension develops, and this taxes the immature heart and circulatory system. (3) Liver enlargement and the prolonged need for RBC production results in decreased ability to make other proteins, such as albumin, and this decreases the oncotic pressure leading to leakage of fluid into tissues and body cavities, termed hydrops fetalis.
|
|
The term "Ulysses Syndrome" has alternatively been used to refer to the psychological and physical sequelae of misdiagnosis due to a false positive result. For instance, a patient who complains of low risk chest pain may be referred for further cardiac work-up by an overcautious physician. These tests in turn may give a positive result due to high sensitivity, which subjects the patient to further testing that ultimately proves to be unnecessary. Victims of this condition experience the stress of being diagnosed with a condition they do not have as well as the physical trauma of invasive testing. There is currently no consensus on the definitive use of the term “Ulysses syndrome”.
|
|
His practice in Cavendish, Vermont, where Gage's accident occurred in 1848, brought Gage under his care. In 1857 he left Cavendish due to poor health, and spent three years traveling and studying in Minnesota and Philadelphia before taking up practice in Woburn, Massachusetts in 1861. His first paper on Gage appeared in Boston Medical and Surgical Journal in late 1848; a short follow-up note appeared early the next year. Almost twenty years later, in 1868, he published a final paper recounting what he had been able to learn about the subsequent history of his patient (who died in 1860), and presenting psychological changes in Gage which, presumably, were sequelae of the accident.
|
|
Babesia lifecycle Babesia parasites reproduce in red blood cells, where they can be seen as cross-shaped inclusions (four merozoites asexually budding, but attached together forming a structure looking like a "Maltese cross") and cause hemolytic anemia, quite similar to malaria. Unlike the Plasmodium parasites that cause malaria, Babesia species lack an exoerythrocytic phase, so the liver is usually not affected. In nonhuman animals, Babesia canis rossi, Babesia bigemina, and Babesia bovis cause particularly severe forms of the disease, including a severe haemolytic anaemia, with positive erythrocyte-in-saline-agglutination test indicating an immune-mediated component to the haemolysis. Common sequelae include haemoglobinuria "red-water", disseminated intravascular coagulation, and "cerebral babesiosis" caused by sludging of erythrocytes in cerebral capillaries.
|
|
Many ADPKD patients suffer symptomatic sequelae in consequence of the disease, such as cyst hemorrhage, flank pain, recurrent infections, nephrolithiasis, and symptoms of mass effect (i.e., early satiety, nausea and vomiting, and abdominal discomfort), from their enlarged kidneys. In such cases, nephrectomy can be required due to intractable symptoms or when in the course of preparing for kidney transplantation, the native kidneys are found to impinge upon the true pelvis and preclude the placement of a donor allograft. Additionally, native nephrectomy may be undertaken in the presence of suspected malignancy, as renal cell carcinoma (RCC) is two to three times more likely in the ADPKD population in end-stage kidney disease (ESKD) than in the ESKD patients without ADPKD.
|
|
Grade 1: if there is no initial lesion on the area, no amputation or lasting effects are expected Grade 2: if there is a lesion on the distal body part, tissue and fingernails can be destroyed Grade 3: if there is a lesion on the intermediate or near body part, autoamputation and loss of function can occur Grade 4: if there is a lesion very near the body (such as the carpals of the hand), the limb can be lost. Sepsis and/or other systemic problems are expected. A number of long term sequelae can occur after frostbite. These include transient or permanent changes in sensation, paresthesia, increased sweating, cancers, and bone destruction/arthritis in the area affected.
|
|
Bird also designed the European Union's robust surveillance for transmissible spongiform encephalopathies in sheep which revolutionised the understanding of scrapie. Record linkage studies in Scotland were central to Bird's work (with others) on the late sequelae of Hepatitis C virus infection and on the morbidity and mortality of opioid addiction. Her team first quantified the very high risk of drugs-related death in the fortnight after prison-release, in response to which Bird and Hutchinson proposed a prison-based randomized controlled trial of naloxone, the opioid antagonist, for prisoners-on-release who had a history of heroin injection. Bird introduced the Royal Statistical Society’s statistical seminars for journalists and awards for statistical excellence in journalism.
|
|
Post-traumatic stress disorder (PTSD) was included in the DSM-III (1980), mainly due to the relatively large numbers of American combat veterans of the Vietnam War who were seeking treatment for the lingering effects of combat stress. In the 1980s, various researchers and clinicians suggested that PTSD might also accurately describe the sequelae of such traumas as child sexual abuse and domestic abuse. However, it was soon suggested that PTSD failed to account for the cluster of symptoms that were often observed in cases of prolonged abuse, particularly that which was perpetrated against children by caregivers during multiple childhood and adolescent developmental stages. Such patients were often extremely difficult to treat with established methods.
|
|
There they nearly perish, but they save their marriage by winning their way through to a satisfactory mutual understanding. The novel ends as they are returning to London to undertake, together, a critical engagement with the world. Trafford intends to devote himself to writing a book entitled From Realism to Reality, which is to be "a pragmatist essay, a sustained attempt to undermine the confidence of all that scholasticism and logic chopping which still lingers like the sequelae of a disease in our University philosophy," while Marjorie intends to devote herself to being "his squaw and body-servant first of all, and then—a mother."H.G. Wells, Marriage (London: Macmillan, 1912), pp.
|
|
Although the original TN model specifically focused on the relationship between early traumatic events and schizophrenia symptoms it has since expanded to include all psychosis and psychotic disorders. Since its proposal, research of links between childhood trauma and psychosis has proliferated, resulting in numerous studies (using both human subjects and animal-models) providing both direct and indirect support of the TN model. Importantly, while the TN model suggests the psychological sequelae of childhood trauma may initiate neurodevelopmental changes resulting in psychopathology, it is not indicative of brain disease. This is a marked contrast from previous popular beliefs that the biological etiology of psychosis rendered it largely irreversible and untreatable, aside from pharmacotherapy-based symptom management.
|
|
Cortical stimulation mapping may be used in neuro-oncology as a tool to identify the areas of a patient's brain that are critical for functions such as the language and motor pathways. This procedure is considered standard for operations involving gliomas in order to reduce loss of motor function and overall morbidity. Pre-surgical planning allows for the physician to avoid these high-risk areas as much as possible during a tumor resection, minimizing potential loss of function and development of sequelae. Patients whose surgeon uses cortical stimulation mapping to assess the anatomy and function of rolandic areas have a greater chance and faster rate of regaining baseline function post-operatively than those who undergo surgeries that avoid this technique.
|
|
For Hobbes the multitude was a rabble that needed to enact a social contract with a monarch, thus turning them from a multitude into a people. For Machiavelli and Spinoza both, the role of the multitude vacillates between admiration and contempt. Recently the term has returned to prominence as a new model of resistance against global systems of power as described by political theorists Michael Hardt and Antonio Negri in their international best-seller Empire (2000) and expanded upon in their Multitude: War and Democracy in the Age of Empire (2004). Other theorists recently began to use the term include political thinkers associated with autonomist Marxism and its sequelae, including Sylvère Lotringer, Paolo Virno, and thinkers connected with the eponymous review Multitudes.
|
|
The abuse- deterring effects of atropine when used as an adulterant are reasonably effective in reducing the combination's potential for recreational use. It combines the mechanisms of naloxone and paracetamol (the two more commonly used abuse-deterring agents) by increasing the likelihood of the overdose resulting in harmful and/or fatal sequelae (as does paracetamol), in addition to reliably producing unpleasant side-effects which "spoil" the opioid euphoria and discourage abusers from overdosing again following their initial experience (as does naloxone). This does not deter the use of single doses of difenoxin to potentiate another opiate, the anticholingeric activity of a single tablet is actually likely to increase the pleasurable effects of opioid use in a manner similar to combining one or more opioids with orphenadrine.
|
|
When some of these children become parents, especially if they suffer from posttraumatic stress disorder (PTSD), dissociative symptoms, and other sequelae of child abuse, they may encounter difficulty when faced with their infant and young children's needs and normative distress, which may in turn lead to adverse consequences for their child's social-emotional development. Additionally, children may find it difficult to feel empathy towards themselves or others, which may cause them to feel alone and unable to make friends. Despite these potential difficulties, psychosocial intervention can be effective, at least in some cases, in changing the ways maltreated parents think about their young children. Victims of childhood abuse also suffer from different types of physical health problems later in life.
|
|
During his work as director of infant mental health services at the Columbia University Medical Center (1998–2008), Schechter found that the large majority of inner-city mothers who were requesting consultation for their infants and young children for reasons of behavioral difficulties had histories of childhood maltreatment and/or family violence victimization and exposure, often with related psychiatric sequelae (i.e. PTSD, major depression, dissociation, and personality disorder). He further observed that many of these traumatized mothers, despite their best intentions, not only had great difficulty in "reading" and tolerating their infants' distress, but that they also had a tendency to misattribute their children's intentions and personality characteristics.Schechter DS, Coots T, Zeanah CH, Davies, M, Coates SW, Trabka KA, Marshall RD, Liebowitz MR, Myers MM (2005).
|
|
Because of the ease of therapy (dietary exclusion of fructose), HFI can be effectively managed if properly diagnosed. In HFI, the diagnosis of homozygotes is difficult, requiring a genomic DNA screening with allele specific probes or an enzyme assay from a liver biopsy. Once identified, parents of infants who carry mutant aldolase B alleles leading to HFI, or older individuals who have clinical histories compatible with HFI can be identified and counselled with regard to preventive therapy: dietary exclusion of foods containing fructose, sucrose, or sorbitol. If possible, individuals who suspect they might have HFI, should avoid testing via fructose challenge as the results are non- conclusive for individuals with HFI and even if the diagnostic administration fructose is properly controlled, profound hypoglycemia and its sequelae can threaten the patient's well-being.
|
|
During her time in England, she contracted poliomyelitis, the sequelae of which would progressively affect her ability to walk, particularly during her senior years. She earned her Bachelor of Science (with Honours) degree in 1948 and her Master of Science degrees in 1959, both at Liverpool University. In 1983, she was awarded a Doctor of Science (Hon.) degree by the University of the Witwatersrand, Johannesburg, South Africa. Dr. Walker was first employed in 1949 in the Research Branch of Her Majesty’s Overseas Civil Service as a Research Officer in the East African Veterinary Research Organization in Muguga, Kenya, where she rose to Principal Scientific Officer before taking up a post as Senior Professional Officer at the Veterinary Research Institute, Onderstepoort, in 1966 upon the retirement of Dr. Gertrud Theiler.
|
|
Perinatal asphyxia is also an oxygen deficit from the 28th week of gestation to the first seven days following delivery. It is also an insult to the fetus or newborn due to lack of oxygen or lack of perfusion to various organs and may be associated with a lack of ventilation. In accordance with WHO, perinatal asphyxia is characterised by- Profound metabolic acidosis, with a PH <7.20 on umbilical cord arterial blood sample, Persistence of an APGAR score of 3 at the 5th minute, Clinical neurologic sequelae in the immediate neonatal period,Evidence of multiorgan system dysfunction in the immediate neonatal period. Hypoxic damage can occur to most of the infant's organs (heart, lungs, liver, gut, kidneys), but brain damage is of most concern and perhaps the least likely to quickly or completely heal.
|
|
Regardless of the specific diagnosis (Lyme, Rocky Mountain Spotted Fever, Colorado Tick Fever, Babesiosis etc.) the key to management and prevention of sequelae is early identification of disease and initiation of appropriate antibiotic therapy. With regard to the effects of a warming world and the expansion of tick populations to previously unexposed areas, adaptive keys to prevention will include expansion of health care infrastructure and pharmacologic availability, as well as education of people and providers as to the risks of disease and preventive measures they can take. In the face of these expanding threats, strong collaboration between government officials and environmental scientists is necessary for advancing preventive and reactive response measures. Without acknowledging the climate changes that make environments more habitable for disease carriers, policy and infrastructure will lag behind vector borne disease spread.
|
|
However, Mizutani was not awarded the 1975 medicine prize along with Temin. :As of 2015, there have been seven Japanese who have received the Lasker Award and twelve Japanese who have received the Canada Gairdner International Award, but only three Japanese who have received the Nobel Prize in Physiology or Medicine. ;Others :A number of important Japanese native scientists were not nominated for early Nobel Prizes, such as Yasuhiko Kojima and Yasuichi Nagano (jointly discovered Interferon), Jōkichi Takamine (first isolated epinephrine), Kiyoshi Shiga (discovered Shigella dysenteriae), Tomisaku Kawasaki (Kawasaki disease is named after him), and Hakaru Hashimoto. After World War II, Reiji Okazaki and his wife Tsuneko were known for describing the role of Okazaki fragments, but he died of leukemia (sequelae of the atomic bombing of Hiroshima) in 1975 at the age of 44.
|
|
The radial artery may also be used for cannulation; this approach offers several advantages, including the accessibility of the artery in most patients, the easy control of bleeding even in anticoagulated patients, the enhancement of comfort because patients are capable of sitting up and walking immediately following the procedure, and the near absence of clinically significant sequelae in patients with a normal Allen test. Downsides to this approach include spasm of the artery and pain, inability to use larger catheters needed in some procedures, and more radiation exposure. The main advantages of using the interventional cardiology or radiology approach are the avoidance of the scars and pain, and long post- operative recovery. Additionally, interventional cardiology procedure of primary angioplasty is now the gold standard of care for an acute myocardial infarction.
|
|
Aspects of PTSD in soldiers of ancient Assyria have been identified using written sources from 1300–600 BCE. These Assyrian soldiers would undergo a three-year rotation of combat before being allowed to return home, and were purported to have faced immense challenges in reconciling their past actions in war with their civilian lives. Connections between the actions of Viking berserkers and the hyperarousal of post-traumatic stress disorder have also been drawn. The researchers from the Grady Trauma Project highlight the tendency people have to focus on the combat side of PTSD: "less public awareness has focused on civilian PTSD, which results from trauma exposure that is not combat related... " and "much of the research on civilian PTSD has focused on the sequelae of a single, disastrous event, such as the Oklahoma City bombing, September 11th attacks, and Hurricane Katrina".
|
|
On 23 August 1946, Denise Jacob testified about her experiences. Roughly translated from the original French, she said: > The pain, the cold, the hunger, the thirst, the lack of sleep, the > insurmountable misery that is overcome, the body, except serious sequelae, > forgets them in an unconscious space. The images that will remain forever: > Those of thousands of women lined up by tens, standing in the cold or the > heat, planted for hours waiting for the end-of-call siren, images of the > more and more emaciated bodies of our companions, the unknown dead, image of > a face absent from view, image of the superimposed bedsteads with the > youngest at the top, and the least mobile, older; downstairs, sharing two or > three depending on the time a straw mattress 70 cm wide. There remain the > faces, the silhouettes of those who have not returned.
|
|
The potential for significant psychological sequelae after indirect exposure to oil spills and other environmental disasters has been well documented. These parallel the psychological distress associated with direct disaster exposure and include symptoms of depression, anxiety, and post-traumatic stress disorder A 2011 study looked at the psychological impacts of the Gulf spill on Florida and Alabama communities. The study concluded that the current estimates of human health impacts associated with the oil spill may underestimate the psychological impact in Gulf Coast communities that did not experience direct exposure to oil and that income loss after the spill may have a greater psychological health impact than the presence of oil on the immediately adjacent shoreline. In Louisiana, a unique combination of past environmental exposures, health disparities, and the disaster of the oil spill were found to coincide with mental health problems, primarily depression.
|
|
Smalley joined the faculty at UCLA after she completed post-doctoral fellowships in medical genetics and childhood psychopathology, moving from assistant to full professor until her retirement to emeritus in 2011. In 1988 she published a review paper on the genetics of autism in JAMA Psychiatry. Following its publication, she received a National Institute of Health (NIH) grant to investigate genetic determinants in autism, and pioneered an approach to behavioral genetics by studying known genetic disorders with behavioral sequelae, specifically, the study of tuberous sclerosis complex, (TSC), a genetic disorder in which autistic disorder occurs at higher rates than the general population. She continued to research autism for the following ten years, producing numerous papers on the genetics and subclinical variants of autism beyond the diagnostic classification as well as genetic and behavioral studies of TSC.
|
|
S100B serum levels are elevated before seizures suggesting that BBB leakage may be an early event in seizure development. An extremely important application of serum S100B testing is in the selection of patients with minor head injury who do not need further neuroradiological evaluation, as studies comparing CT scans and S100B levels have demonstrated S100B values below 0.12 ng/mL are associated with low risk of obvious neuroradiological changes (such as intracranial hemorrhage or brain swelling) or significant clinical sequelae. The excellent negative predictive value of S100B in several neurological conditions is due to the fact that serum S100B levels reflect blood–brain barrier permeability changes even in absence of neuronal injury. In addition, S100B, which is also present in human melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
|
|
On January 31, 2009 PACE and the Hib Initiative hosted Childhood Pneumonia and Meningitis: Recent Advances at Aga Khan University in Karachi, Pakistan. The event, brought together stakeholders in child health from Pakistan, including health professionals, representatives from the Ministry of Health and EPI officials. Event leaders, PACE Co-chair Dr. Ciro de Quadros and PACE member Dr. Zulfiqar Bhutta, highlighted the role of advocacy in combating childhood pneumonia and meningitis. On March 3, 2009, PACE, in conjunction with the Sabin Vaccine Institute, PneumoADIP and the WHO, hosted a media briefing at the Sabin Vaccine Institute's 4th Regional Pneumococcal Symposium in Johannesburg, South Africa, at which PACE released two new studies, Sequelae Due to Bacterial Meningitis among African Children: A Systematic Literature Review, and Bacterial Infections in Persons with Sickle Cell Disease: A Review of Data from Africa with a Focus on Pneumococcal Disease.
|
|
In Shmotkin's studies, Holocaust survivors present a paradigm of extreme trauma happening early in life with sequelae lingering up to their old age. In his approach, the trauma is a test case for the functionality of the happiness- promoting systems in tackling the intensified hostile-world scenario and suggesting a world of normalcy. By studying Holocaust survivors in an array of community and national samples, Shmotkin and his colleagues highlighted a consistent conclusion that older survivors usually manifested general resilience in most life domains along with specific vulnerabilities in pertinent psychosocial issues. Coping with the trauma was modulated by properties of the survivors’ time perspective on their period of traumatization and their ability to incorporate the trauma into a coherent life story. In reviews of research on Holocaust survivors, Shmotkin explicated how long-term effects of the survivors’ trauma interacted with aging processes and family constellation.
|
|
Nutrition disorders and nutritional deficits may cause neurodevelopmental disorders, such as spina bifida, and the rarely occurring anencephaly, both of which are neural tube defects with malformation and dysfunction of the nervous system and its supporting structures, leading to serious physical disability and emotional sequelae. The most common nutritional cause of neural tube defects is folic acid deficiency in the mother, a B vitamin usually found in fruits, vegetables, whole grains, and milk products. (Neural tube defects are also caused by medications and other environmental causes, many of which interfere with folate metabolism, thus they are considered to have multifactorial causes.) Another deficiency, iodine deficiency, produces a spectrum of neurodevelopmental disorders ranging from mild emotional disturbance to severe mental retardation. (see also congenital iodine deficiency syndrome) Excesses in both maternal and infant diets may cause disorders as well, with foods or food supplements proving toxic in large amounts.
|
|
A fundamentally different, even if not competing view, of the very same phenomenon is central to Belsky'sBelsky 1997b; 1997a; 2005 differential susceptibility hypothesis and Boyce and Ellis' (2005) related notion of biological sensitivity to context: Individuals do not simply vary in the degree to which they are vulnerable to the negative effects of adverse experience but, more generally, in their developmental plasticity. On this hypothesis, more "plastic" or malleable individuals are more susceptible than others to environmental influences in a for-better-and-for-worse manner.Belsky, Bakermans-Kranenburg, & van IJzendoorn, 2007 That is, susceptible to both the adverse developmental sequelae associated with negative environments and the positive developmental consequences of supportive ones. Less susceptible individuals, in contrast, are less affected by rearing conditions, be they presumptively supportive or undermining of well being (see Figure 2, an adaptation of Bakermans-Kranenburg and Van IJzendoorn's (2007) Figure 1).
|
|
Where some function remains in the affected eye, the preferred procedure depends upon the degree of development of muscle sequelae. In a sixth nerve palsy one would expect that, over the 6 month observation period, most patients would show the following pattern of changes to their ocular muscle actions: firstly, an overaction of the medial rectus of the affected eye, then an overaction of the medial rectus of the contraletral eye and, finally, an underaction of the lateral rectus of the unaffected eye - something known as an inhibitional palsy. These changes serve to reduce the variation in the misalignment of the two eyes in different gaze positions (incomitance). Where this process has fully developed, the preferred option is a simple recession, or weakening, of the medial rectus of the affected eye, combined with a resection, or strengthening, of the lateral rectus of the same eye.
|
|
PACE commissioned two studies, Sequelae Due to Bacterial Meningitis among African Children: A Systematic Literature Review, and Bacterial Infections in Persons with Sickle Cell Disease: A Review of Data from Africa with a Focus on Pneumococcal Disease, that highlighted the increased risk for children in Africa of contracting pneumococcal disease and suffering its devastating consequences. It was found that African children who contract pneumococcal disease are 36 times as likely to have sickle-cell disease, a blood disorder prevalent in African children that increases the risk for infectious diseases and early death. Inn addition, the research showed that up to one-half of all children in Africa who get pneumococcal meningitis will either die or be disabled as a consequence of the disease, even when treated with antibiotics in a hospital. As the three leading causes of bacterial meningitis in childhood are vaccine preventable, the regular use of conjugate vaccines would reduce the high burden of morbidity and mortality in both epidemic and endemic settings.
|
|
Knee injury caused by a punishment shooting According to psychiatrist Oscar Daly, who treats victims of the attacks, the characteristics of those who tend to be victims—such as poor parenting and preexisting mental health problems—make them more vulnerable to psychological sequelae. A 1995 study found that symptoms of post-traumatic stress disorder, such as flashbacks, hypervigilance, difficulty concentrating, and attempts to numb or minimize the incident, are common in youth who survive a punishment attack. According Hamill's research, desire to escape fear and the feeling of powerlessness can contribute to problems with alcoholism and drug abuse. More than one third of her subjects suffered from extended bouts of depression following attacks and 22% said that they had attempted suicide. Mallon analyzed the 402 suicides in Northern Ireland between 2007 and 2009 and identified nineteen cases in which young men had killed themselves after being threatened with punishment attacks for alleged criminal or anti-social behaviour.
|
|
In sweeping detail, The Ghosts of Gombe reveals for the first time the full story of day-to-day life at Goodall's wilderness camp—the people and the animals, the stresses and excitements, the social conflicts and cultural alignments, and the astonishing friendships that developed between three of the researchers and three of the chimpanzees—during the months preceding that tragic event. At the same time, it gathers together the story of the young woman's death, examines how it might have happened, and explores some of the painful sequelae that haunted two of the survivors for the rest of their lives. In 2010, Peterson founded the Henry David Thoreau Prize for Literary Excellence in Nature Writing, an annual literary award designed to honor America’s best nature writers. Originally conceived as a program supported and administered by PEN New England, the Thoreau Prize is currently supported and administered by The Thoreau Society, Inc.
|
|
Diffusion MRI allows us to detect in the context of the emergency, a few hours after the onset of a stroke, the area of the brain that is dying because it is deprived of blood flow when a blood vessel has been obliterated by a clot. The consequences of stroke are formidable: it is the third leading cause of death, and in 30% of cases it leaves severe functional sequelae (hemiplegia, speech disorders) in patients who become unable to support themselves. Stroke is by far the leading source of disability in the long term, with significant social and economic consequences. Diffusion MRI has led to the urgent and accurate identification of strokeDenis Le Bihan, Le cerveau de cristal : Ce que nous révèle la neuro- imagerie, Odile Jacob, Paris, 2012 and the development of drugs that, injected in the very first hours following stroke, can dissolve the clot and immediately clear up symptoms.
|
|
The racially-motivated boycott presaged the Crown Heights riot the following year, which further compromised relations between Jewish-American and African- American communities in the borough, and diminished support for mayor David Dinkins' tenure in the city. In addition, some protesters were also entangled in a culture of poverty, whose psychosocial sequelae - such as anomie, recidivism, educational disparities and lack of economic opportunities - may have contributed to their hostility toward Asian-American and Jewish-American minorities, as well as African-American mayor Dinkins, who was assailed by black protesters after shopping at Family Red Apple in an unsuccessful attempt to defuse the conflict. During the latter half of the 1990s, as crime and unemployment rates plummeted in the city, community relations between erstwhile black protesters - some of whom were radicalized by the racialist rhetoric espoused by black nationalists such as Robert (Sonny) Carson - and Asian and Jewish residents generally improved. As early as 1991, the Family Red Apple boycott ended amicably, with a "steady stream of customers" frequenting the Korean-owned grocery store after the previous owner relinquished his lease.
|
|
Psychological dependence is more common in those who abuse carisoprodol and those who have a history of drug abuse (particularly sedatives or alcohol). It may reach clinical significance before physiological tolerance and dependence have occurred and (as with benzodiazepines) has been demonstrated to persist to varying degrees of severity for months or years after discontinuation. Discontinuation of carisoprodol, as with all GABA- ergics, can result in cognitive changes which persist for weeks, months, or rarely even years including greatly increased anxiety and depression, social withdrawal, hair-trigger agitation/aggression, chronic insomnia, new or aggravated (often illogical) phobias, reduced IQ, short term and long-term memory loss, and dozens of other sequelae. The effects, severity, and duration appear to be slightly dose-dependent but are mainly determined by the patients pattern of use (taken as prescribed, taken in bulk doses, mixed with other drugs, a combination of the above, etc.), genetic predisposition to drug abuse, and a history of substance abuse all increase the patients risk of persistent discontinuation syndrome symptoms.
|
|
Cases of GAS are still present today, but were also evident before World War I. This was shown by a training camp located in Texas, where a harmful strain of pneumonia complicating measles was caused by a strain of Streptococcus. Existence of streptococci strains was additionally found in World War II. An epidemic of streptococcal infection in the United States Navy during this war indicated that this type of disease was able to exist and spread in formerly unexposed individuals by environments that serological types of group A streptococci preferred. In later years, a positive test result for the presence of group A streptococci was found in 32.1 percent of individuals after throat cultures were carried out in a 20 yearlong (1953/1954-1973/1974) study performed in Nashville, TN. Also, from 1972-1974, recurring GAS illness was observed with a prevalence of 19 percent in school-aged children as well as a prevalence rate of 25 percent in families. The severity of streptococcal infections has decreased over the years, and so has rheumatic fever (a sequelae of GAS) which is indicated by the change in numerous hospitals from containing wards allocated for the sole purpose of treating rheumatic fever to hardly seeing the disease at all.
|
|