51 Sentences With "laddering" | Random Sentence Generator

Are those check marks or dashes laddering the left side?

So laddering can offer flexibility in the face of uncertainty.

If interest rates rise, your laddering strategy will benefit from the higher rates.

But focusing on short-term performance misses the point of choosing a laddering plan, he said.

Though I didn't know it, I was doing a kind of CD laddering, and it worked.

"Laddering still makes sense," said Patricia Seaman, a spokeswoman for the National Endowment for Financial Education.

Another downside is that that the laddering system could exacerbate the diversity issues big tech companies face.

Here are some questions and answers about C.D.s and laddering: Are C.D.s suitable for holding emergency funds?

Wescott's Rawdin said persistently low interest rates have made bond laddering (where bond durations are staggered) less attractive.

If you are adamant about owning CDs in a rising-interest-rate environment, a laddering approach may be prudent.

Traditionally, laddering has entailed building a portfolio of individual bonds with staggered maturities so that portions of the portfolio mature each year.

Many investors are turning to exchange-traded funds that make laddering easier, a market where ETF leaders Invesco and BlackRock are attracting the most assets.

For instance, investors who want a credited rate of interest over a specified period of time might also want to consider laddering certificates of deposit.

For retirees and pre-retirees, bond laddering — that is, buying a series of bonds that mature in different years — may help reduce interest rate risk.

But laddering the ages of the staff, from Generation X to millennials, has helped to address the different concerns of clients who span those same generations.

To create a laddering strategy, which pairs CDs of various durations, McBride recommended starting now with the shorter-duration CDs and then waiting until rates climb again to buy longer term.

My colleagues and I all worked for many years in the traditional environment of big consulting firms and saw first-hand how counter-productive the laddering promotions structure within these firms is.

Laddering strategies can include bonds due as much as a decade into the future, and each fund can hold as many as several hundred bonds to hold down default risk from any one borrower.

Once you've determined that, then use data to back up the important points that lead to that recommendation, making sure that each point logically leads into the next one, laddering up to the final recommendation.

One drawback to C.D. laddering is that you must keep track of the various certificate maturity dates and research interest rates before rolling your money into a new C.D. "You constantly have a C.D. maturing," said Ken Hoyt, a fee-only financial adviser in Westford, Mass.

Kitchen sink drama is having an affair and saying "I'm having an affair," it's shagging in a car park and laddering your tights as you pull them back up, it's smoking a fag with shaking hands and it's sordid goings-on in a Travelodge off the M1.

The next it's the middle of July, strawberries gone and sour cherries on their way out, passable corn coming in from the farms down south, pretty good tomatoes, too, and before long there'll be fireworks going for Labor Day and everyone back in hard shoes for those meetings with the senior VPs, the kind that end with resets and pivots, everyone laddering up toward deliverables, iterative releases, the language of woe.

This is due to DNA fragmentation taking place in a later stage of the apoptosis process. DNA laddering is used to test for apoptosis of many cells, and is not accurate at testing for only a few cells that committed apoptosis. To enhance the accuracy in testing for apoptosis, other assays are used along with DNA laddering such as TEM and TUNEL. With recent improvements to DNA laddering, DNA laddering has become a more reliable, and reasonable technique to use when detecting apoptosis.

It is also important to note that DNA laddering occurs differently depending on the type of cell, so there may be slight changes in the process of DNA laddering depending on the cell that is being investigated.

Some of the plus points of the laddering technique is that it provides reasoning behind certain behaviors and or choices. Laddering is a way to draw out a response or answer from someone that might not be revealed through other conventional methods.

Laddering is an investment technique that requires investors to purchase multiple financial products with different maturity dates.

While most of the morphological features of apoptotic cells are short-lived, DNA laddering can be used as final state read-out method and has therefore become a reliable method to distinguish apoptosis from necrosis. DNA laddering can also be used to see if cells underwent apoptosis in the presence of a virus. This is useful because it can help determine the effects a virus has on a cell. DNA laddering can only be used to detect apoptosis during the later stages of apoptosis.

Thomas J. Reynolds and Jonathan Gutman were the founders and pioneers of the laddering theory. Originally, laddering came from consumer research, laddering is derivative from the Means-End Theory as proposed by Gutman. Means-End Theory states that people choose a product because it contains attributes (the means) that are instrumental in achieving the desired consequences and fulfilling values (the ends). To put it another way, consumer behaviour is dependent on how the user perceives certain product attributes, these are likely to have certain desired consequences, which are also seemingly beneficial to their individual values.

These give a characteristic "laddered" appearance on agar gel after electrophoresis. Tests for DNA laddering differentiate apoptosis from ischemic or toxic cell death.

DNA laddering (left) visualised in an agarose gel by ethidium bromide staining. A 1 kb marker (middle) and control DNA (right) are included. DNA laddering is a feature that can be observed when DNA fragments, resulting from apoptotic DNA fragmentation, are visualized after separation by gel electrophoresis. It was first described in 1980 by Andrew Wyllie at the University of Edinburgh Medical School.

Before getting into this specifics of interviewing techniques, it is important to identify the problems associated with laddering. The two most common problems are outlined below.

This can be advantageous, as smaller banks may not offer the longer terms of some larger banks. Although laddering is most common with CDs, investors may use this strategy on any time deposit account with similar terms.

DNA laddering is a distinctive feature of DNA degraded by caspase-activated DNase (CAD), which is a key event during apoptosis. CAD cleaves genomic DNA at internucleosomal linker regions, resulting in DNA fragments that are multiples of 180–185 base-pairs in length. Separation of the fragments by agarose gel electrophoresis and subsequent visualization, for example by ethidium bromide staining, results in a characteristic "ladder" pattern. A simple method of selective extraction of fragmented DNA from apoptotic cells without the presence of high molecular weight DNA sections, generating the laddering pattern, utilizes pretreatment of cells in ethanol.

By comparison, in a barbell strategy the maturity of the bonds included in the portfolio is concentrated at two extreme maturities, while in the strategy referred to as laddering or ladder strategy the portfolio is constructed to have approximately equal amounts of each maturity.

Laddering can free up capital as needed. A person may purchase a shorter term bond in the event that he needs the capital soon to fund his children's tuition while purchasing other longer term bonds that mature later as retirement spending with a more favorable rate, assuming the economy is experiencing a normal yield curve during this time. Laddering can also be used as an overall retirement planning approach for all retirement investments. The idea is to separate CDs, cash, bonds, annuities, and others into different "ladders" (or "buckets" or "baskets") depending on when the asset is expected to be liquidated to fund the retirement revenue stream.

In the beginning of the interview process, the interviewer should build good rapport with the interviewee. Making the respondent aware that they will not be judged for their right and wrong answers. By adapting this technique of environment the purpose of the laddering interview can be accomplished.

The apoptotic DNA fragmentation is being used as a marker of apoptosis and for identification of apoptotic cells either via the DNA laddering assay, the TUNEL assay, or the by detection of cells with fractional DNA content ("sub G1 cells") on DNA content frequency histograms e.g. as in the Nicoletti assay.

Another example of twinking can be found in the MMORPG Anarchy Online where twinking is performed by buffing base stats using items (stat buffing weapons, armour) and laddering implants (laddering is a method by which the character equips higher implants by climbing quality levels one by one as one does, a ladder). Once a high-stat buffing item is equipped, it stays equipped even if the stats required to initially equip it decline or wear off, though a penalty can be applied if the base stats fall too far below the equipping requirements. Twinking is an essential component to this game in both PvP and in soloing Instances within the game. Whereas twinking is seen in negative light in other MMORPGS it is seen in positive light in Anarchy Online.

The high-pressure cylinder bore is about in diameter while the low-pressure cylinder bore is about in diameter. The stroke of both cylinders was , while the flywheel is in diameter, and wide. The engine is mounted on a concrete base, with a concrete trough for the flywheel. Some timber relics, plus metal objects such as piping and laddering, also survive on the site.

In 2001, Parasuraman and Colby published their book on consumer technology behavior, Techno-Ready Marketing: How and Why your Customers Adopt Technology.Techno-Ready Marketing: How and Why your Customers Adopt Technology, Retrieved on 2009-07-27. In 2004, Rockbridge partnered with Dr. Tom Reynolds to implement a means-end methodology based on laddering interviews on the Internet.Understanding the Hearts and Minds of Buyers: An Interview with Dr. Thomas J. Reynolds, Retrieved on 2009-07-27.

Apoptotic DNA fragmentation, visualised by the DNA laddering assay (left). A 1 kb marker (middle) and control DNA (right) are included for comparison. Apoptotic DNA fragmentation is a key feature of apoptosis, a type of programmed cell death. Apoptosis is characterized by the activation of endogenous endonucleases, particularly the caspase-3 activated DNase (CAD), with subsequent cleavage of nuclear DNA into internucleosomal fragments of roughly 180 base pairs (bp) and multiples thereof (360, 540 etc.).

Laddering also describes a process where, in order to purchase shares at a given price, investors must also agree to purchase additional shares at a higher price. This artificially inflates the price of the stock and allows insiders to buy at the lower price, with a guarantee that they will be able to sell at a higher price. This practice has resulted in investigations of national and global banks by the SEC after the stock market collapse.

This technique is used for marketing in order to see what values inspire the consumption of the particular product. A chocolate bar producer would do this test so they can match the most common terminal virtue to their product in an advertisement. For example, the virtue of justice, or a virtue of efficiency, or in the above example, the virtue of childhood. The Laddering technique allows businesses get to know their customers better by asking them simple direct questions.

InterViews, 2nd Edition. Thousand Oaks: SAGE. They can follow diverse formats; for example, in a ladder interview, a respondent's answers typically guide subsequent interviews, with the object being to explore a respondent's subconscious motives.2009, Uxmatters, Laddering: A research interview technique for uncovering core values Typically the interviewer has some way of recording the information that is gleaned from the interviewee, often by keeping notes with a pencil and paper, or with a video or audio recorder.

Once inside the target cell, granzyme B can cleave and activate initiator caspases 8 and 10, and executioner caspases 3 and 7 which trigger apoptosis. Caspase 7 is the most sensitive to granzyme B and caspases 3, 8, and 10 are only cleaved to intermediate fragments and need further cleavage for full activation. Granzyme B can also cleave BID leading to BAX/BAK oligomerisation and cytochrome c release from the mitochondria. Granzyme B can cleave ICAD leading to DNA fragmentation and the laddering pattern associated with apoptosis.

The nucleosome core particle (shown in the figure) consists of about 146 base pair of DNA wrapped in 1.67 left-handed superhelical turns around the histone octamer, consisting of 2 copies each of the core histones H2A, H2B, H3, and H4. Adjacent nucleosomes are joined by a stretch of free DNA termed linker DNA (which varies from 10 - 80 bp in length depending on species and tissue type).The whole structure generates a cylinder of diameter 11 nm and a height of 5.5 nm. Apoptotic DNA laddering.

The school has a strict code of conduct. Girls must adhere to the rules obediently. In KS3, girls are to wear a navy blue blazer with the school logo on the chest pocket, a navy blue jumper with the school crest(optional), a blue blouse (in the summer term: worn without a tie), or a winter shirt alongside a house tie – girls are notified of their houses before beginning the school), navy blue tights (preferably 60 dernier to avoid laddering) and black shoes. No boots, trainers or any other kind are permitted.

In KS4, girls are to wear a navy blue cardigan, a navy blue jumper with the school crest(optional), a blue blouse (in the summer term: worn without a tie), or a winter shirt alongside a house tie – girls are notified of their houses before beginning the school), navy blue tights (preferably 60 dernier to avoid laddering) and black shoes. No boots, trainers or any other kind are permitted.In KS4, girls are permitted to wear a single ring. No jewellery is allowed apart from one pair of stud earrings of a silver or gold colour and a watch.

In January 2005, the Dollar Bank CD Ladder was launched as the first CD of its kind. Laddering is based upon the premise of not putting all money in a single CD. By dividing money between CD terms ranging from short to long, CDs with a range of yields that reflect market expectations for the future direction of interest rates are purchased. Dollar Bank was the first to offer text messaging on June 19, 2007, and mobile online banking was introduced on June 5, 2008. On March 11, 2009, Dollar Bank introduced reverse mortgages to provide financial help to seniors.

From top to bottom: Regular yarn, braided yarn, ladder yarn and ribbon yarn Novelty yarns include a wide variety of yarns made with unusual features, structure or fiber composition such as slubs, inclusions, metallic or synthetic fibers, laddering and varying thickness introduced during production. Some linens, wools to be woven into tweed, and the uneven filaments of some types of silk are allowed to retain their normal irregularities, producing the characteristic uneven surface of the finished fabric. Man-made fibres, which can be modified during production, are especially adaptable for special effects such as crimping and texturizing. A hat, scarf, and pair of fingerless gloves made from novelty yarn.

Laddering avoids the risk of reinvesting a large portion of assets in an unfavorable financial environment. Each "rung" of the ladder is a bond of a specific maturity date and the "height" of the ladder is the difference between the shortest maturity bond and the longest maturity bond. The more rungs in the ladder (10 or more is recommended), the better the diversification, the more stable the yield, and the higher the average yield. For example, a person has both a 2015 matured CD and a 2018 matured CD. Even if the interest rate is low in 2015 when one certificate is to be renewed, half of the income is locked in until 2018.