There was no doubt about her experience and lack of inhibition.
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The booze and a lack of inhibition freed me from my anxiety.
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Symptoms of FTD include a lack of inhibition or social tact and unusual verbal, physical or sexual behavior.
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Drowsiness, lack of inhibition, vomiting, vertigo, a severe headache and abdominal pain are common signs, according to the World Health Organization.
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Despite her lack of inhibition when it came to launching her YouTube channel in the beginning, there's still a lot she keeps offline.
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Played with an exuberant lack of inhibition by Audrey Tautou, Marie's casual attitude toward consent and partnering goes hand in hand with her unresponsiveness.
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The boy Joe wants to be a comedy improviser, and you see that lack of inhibition as soon as he starts contorting his face to the camera.
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Morgan told me he has never felt fully British, which may explain his lack of inhibition when it comes to writing about the country's most powerful people.
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Olivier Abtan of the Boston Consulting Group in Paris describes ever-richer Chinese consumers, with an utter "lack of inhibition" in displaying their wealth, as the best possible boost that the luxury industry could imagine.
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"We wanted to create a show that was slightly more daring than we had done before, a show that embodied the freedom and lack of inhibition that the physical act of a 'one-night stand' suggests," Davis explains.
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The artist turns tourists' gazes back onto them to highlight their lawlessness; their nudity underscores their lack of inhibition but also alludes to colonial, Western constructs of far-off islands as wild, exotic destinations that offer escape from civilization.
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The reason watching Limp Bizkit is so important to me, and perhaps for everyone else still dropping cash on them two decades on, is because they bring a youthful joy and lack of inhibition that tends to go amiss when revisiting more serious bands.
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The graph above the zymogram shows the lack of inhibition of proliferation at this time point.
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Injury and loss of form in the subsequent years restricted him to a total of 84 SANFL games. He later became a football commentator and was famous for his enthusiasm and lack of inhibition.
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The film's protagonist, Jack Skellington is a skeleton who holds the title of The Pumpkin King. He is popular among the residents of Halloween Town, due to his charming personality and aim to please. Despite a lack of inhibition, he means well. He is in charge of Halloween.
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The carnival is celebrated during the four days before the ash wednesday. People party widely and get disguised as an act of fun and a lack of inhibition. During this time, Barranquilla people and foreigners coming in the city submerse themselves in the collective joy, drinking and dancing.
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" He prepared them in detail using storyboards. He also tends to rowdy humour; in his diary, Goebbels wrote that Ritter "makes nationalistic points with a lack of inhibition that would make others blush"Waldman, p. 166. but also noted his heavy touch, writing of Bal paré (1940): "Ritter is not suited to subtle psychological portrayal.
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Katherine Everett (1949) Bricks and Flowers With similar lack of inhibition, as early as 1907 the American heiress Natalie Barney (1875–1972) was leading like-minded women in sapphic dances in her Parisian garden,See Diana Souhami (2004) Wild Girls photographs of which look little different from scenes at Woodstock in 1969 and other "pop" festivals of the late 1960s and early 1970s.
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Being from a rich family, when Nacho finished high school, he went to Los Angeles to study medicine, not knowing that on his last night in Mexico he had impregnated Margarita (Litzy). Lucho had actually drugged both Nacho and Margarita, leading to lack of inhibition and fornication. In the morning Margarita woke up naked and abandoned. She could not find Nacho.
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He is ridiculed and ostracised, as well as marginalised by mainstream society because of his social awkwardness and lack of inhibition. Derek says it is more important to be kind than to be clever or good-looking. Many media sources describe him as autistic, although Gervais firmly denies this. Gervais, in fact, remains carefully ambiguous as to whether Derek is intellectually-challenged, autistic, or otherwise.
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Children who have ADHD were more likely to have difficulty parameterising movements in a consistent way. This has been explained with motor skill impairment either due to lack of attention or lack of inhibition. To anticipate a change of direction between strokes constant visual attention is essential. With inattention, changes will occur too late, resulting in higher letters and poor alignment of letters on the baseline.
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Current research links cystatin B to production of inhibitory neurons known as GABAergic neurons. It has shown that a lack of cystatin B due to a mutation of the CSTB gene leads to a decrease in the number of inhibitory neurons, and this lack of inhibition makes the cells in the brain, particularly the hippocampus, more excitable. It is hypothesized that this increase in excitability is what causes the myoclonic jerks and tonic-clonic seizures in patients with ULD.
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These camera clubs existed ostensibly to promote artistic photography, but in reality, many were merely fronts for the making of pornography. Page entered the field of "glamour photography" as a popular camera club model, working initially with photographer Cass Carr. Her lack of inhibition in posing made her a hit, and her name and image became quickly known in the erotic photography industry. In 1951, Bettie's image appeared in men's magazines such as Wink, Titter, Eyefull and Beauty Parade.
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Tetany or tetanic seizure is a medical sign consisting of the involuntary contraction of muscles, which may be caused by disorders that increase the action potential frequency of muscle cells or the nerves that innervate them. Muscle cramps caused by the disease tetanus are not classified as tetany; rather, they are due to a lack of inhibition to the neurons that supply muscles. Tetanic contractions (physiologic tetanus) are a broad range of muscle contraction types, of which tetany is only one.
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However, loss of any one protein in the four protein KICSTOR complex resulted in a lack of inhibition of mTORC1 by amino acid or glucose deprivation and increased mTORC1 signaling. Thus, KICSTOR is a negative regulator of mTORC1 signaling that functions by localizing GATOR1 to the lysosomal surface as well inhibiting mTORC1 during periods of amino acid or glucose deprivation. How the KICSTOR complex directly inhibits mTORC1 as well as senses amino acid or glucose deprivation remains to be elucidated.
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Du Boulay noted that Tutu was "a man of many layers" and "contradictory tensions". His personality has been described as warm, exuberant, and outgoing. Du Boulay noted that his "typical African warmth and a spontaneous lack of inhibition" proved shocking to many of the "reticent English" whom he encountered when in England, but that it also meant that he had the "ability to endear himself to virtually everyone who actually meets him". Du Boulay noted that as a child, Tutu had been hard-working and "unusually intelligent".
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Methedrone has been found to be a potent serotonin transporter (SERT) and norepinephrine transporter (NET) inhibitor, but a weak dopamine transporter (DAT) inhibitor. Clinically, the DAT/SERT ratio of methedrone is less than one. Other analog compounds commonly have a DAT/SERT ratio less than half, meaning unlike other MDMA-like compounds methedrone does not prefer inhibition of the NET and DAT over the SERT. The resulting lack of inhibition despite its proclivity to release DAT can lead to a life- threatening adrenergic storm.
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As part of economic empowerment, Prajwala helps survivors acquire the skills and capacities needed to gain a dignified livelihood and thrive independently. In the small-scale production-cum-training unit, survivors become experts in non- conventional trades such as welding, bookbinding, carpentry, desktop publishing and screen printing. > Prajwala’s focus has been on tapping the innate potential and strengths of > these survivors in ventures aimed at their re-integration into the > mainstream society as equals. This means capitalising on the strength that > the girls were forced to acquire – their fearlessness and lack of > inhibition.
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The self re-excitation of hyperactive stretch reflexes theory involves a repetitive contract-relax cycle in the affected muscle, which creates oscillatory movements in the affected limb. In order for self re-excitation to exist, both an increase in motor neuron excitability and nerve signal delay are required. Increased motor neuron excitability is likely accomplished by alterations to the net inhibition of neurons occurring as a result of injury to the CNS (stroke/ spinal cord injury). This lack of inhibition biases neurons to a net excitatory state, therefore increasing total signal conduction.
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The metabolic pathway of trospium in humans has not been fully defined. Of the 10% of the dose absorbed, metabolites account for approximately 40% of the excreted dose following oral administration. The major metabolic pathway is hypothesized as ester hydrolysis with subsequent conjugation of benzylic acid to form azoniaspironortropanol with glucuronic acid. Cytochrome P450 is not expected to contribute significantly to the elimination of trospium. Data taken from in vitro human liver microsomes investigating the inhibitory effect of trospium on seven cytochrome P450 isoenzyme substrates (CYP1A2, 2A6, 2C9, 2C19, 2D6, 2E1, and 3A4) suggest a lack of inhibition at clinically relevant concentrations.
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APC/CCdc20 inactivation during early stages of the cell cycle is partially achieved by the protein Emi1. Initial experiments have shown that addition of Emi1 to Xenopus cycling extracts can prevent the destruction of endogenous cyclin A, cyclin B, and mitotic exit, suggesting that Emi1 is able to counteract the activity of the APC. Furthermore, depletion of Emi1 in somatic cells leads to the lack of accumulation of cyclin B. The lack of Emi1 likely leads to a lack of inhibition of the APC preventing cyclin B from accumulating. From these early observations, it has been confirmed that in G2 and early mitosis, Emi1 binds and inhibits Cdc20 by preventing its association with APC substrates.
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The main drawback of the Quicksilver gland is the periodic "Quicksilver Madness": a flaw engineered by scientist Arnaud DeFöhn causes the gland to leak Quicksilver into the brain of the host, leading to a breakdown of higher cortical function, initially causing a lack of inhibition. The eyes become bloodshot and short bursts of pain result, but the host maintains most control over his behavior. However, as the situation progresses, the pain becomes more severe until the host enters the "madness", at which point the pain ceases but the host begins to exhibit violent behaviour accompanied by apparently vastly increased physical strength, pain tolerance, and possibly even resistance to injury, as his "darker impulses" are released. The whites of the eyes become completely red at this stage.
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Miss Jones worked in a discothèque, which was subject to a vicious protection racket, and lived in a flat which, among other things, displayed a large letter "G" above her single bed. Her clothes typified those of "Swinging London" - a John Lennon-style cap, striped tops, miniskirts – and she rode around on a Vespa motor scooter. This was all quite baffling to Adamant, with his Edwardian attitudes to women; in fact, when he first met her, he thought that she was a boy. His initial reluctance to use Miss Jones' flat as an overnight refuge Episode, A Vintage Year for Scoundrels, 23 June 1966 and a scene in which he sees her win a beauty contest and then catches her half-undressed after the show illustrated both his prudery (or maybe, in the latter instance, surprise at the contrast between 1960s' lingerie and Edwardian corsetry) and her lack of inhibition.
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