Moreover, pain and itchiness are apparently antagonistic insofar as scratching is seen as a method of inflicting pain to relieve itchiness.
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I prefer the dialectic itchiness of her rosy kitsch mode.
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Symptoms include severe itchiness, painful sex and abnormal vaginal discharge.
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Photo: Myra Iqbal (Gizmodo)A few days in, the itchiness got worse.
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"It's a great thing to avoid itchiness, oily scalp, allergies," Robin says.
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In its most recent paper, the Duke team found that TRPV4 was also intimately linked to feelings of itchiness after exposing genetically-engineered mice in which the TRPV4 protein had been dialed back to chemicals known to cause itchiness.
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However, Dr. Angela says that if you're only experiencing itchiness, this is unlikely.
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Tree-pollen counts will be high again, causing runny noses, sneezing, and itchiness.
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Itchiness often keeps children from sleeping, and scratching can lead to skin infections.
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" "#psoriaticarthritis is an #invisibleillness and sometimes so is psoriasis (chronic itchiness and chronic fatigue).
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I would always get a cold or weird itchiness anytime I would try to quit.
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Coconut oil hydrates while a blend of peppermint, tea tree, and spearmint oils soothes itchiness.
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How many will put up with itchiness or cholesterol increases that Intercept's pill can cause?
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Once the infection is treated, the odor usually goes away along with accompanying symptoms like itchiness.
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Plus, all three are free of talc, a controversial ingredient that can cause breakouts and itchiness.
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She posted her story on Facebook to urge other pregnant women not to ignore severe itchiness.
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They're usually associated with intense itchiness of the vulva, along with redness, swelling, and burning urine.
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Much of my time was spent aggressively doing the "pat yo' weave, ladies" dance to relieve itchiness.
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Soon those inside the UBS building were providing updates on the MPR Raccoon's progress and itchiness level.
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Symptoms: Psoriasis symptoms include itchiness; tight-looking, red skin; discomfort or pain; and splitting of the skin.
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They prevent sweating and often cause itchiness, redness or other irritation, making them unsuitable for long-term use.
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According to the Mayo Clinic, food allergies are known to cause swelling and itchiness inside the mouth, too.
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Physical itchiness—whether it's from a wool sweater, a mosquito bite, or poison oak—is usually a temporary sensation.
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It helps thoroughly cleanse the scalp and relieve itchiness and discomfort caused by scalp psoriasis, seborrheic dermatitis, and dandruff.
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These more easily treated symptoms can look like scabbing, redness and itchiness of the areas that have been tattooed.
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Worrying about the appearance is the least of it — the itchiness, discomfort, and pain can actually cause serious problems.
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He sighed, applied an ointment for the itchiness, which only made it worse, and admitted that he was baffled.
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Likewise, if you are allergic to the additives in your leather belt, you'll probably feel itchiness around your abdomen.
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To the touch, these sheets are soft and smooth, with none of the itchiness that some feel with sateen sheets.
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If you are allergic, you might experience a runny or stuffy nose, itchiness in your throat, or watery or itchy eyes.
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Aggressive swabbing can also cause tiny cuts in the delicate skin inside the ear, which can cause itchiness or get infected.
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Beyond these simplistic classification attempts, scientists have had a tough time determining what causes itchiness to occur on a cellular level.
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Now, this alone didn't get rid of my irritation or itchiness, but the bumps around my bikini line went down significantly.
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I think I have Bite Helper to thank for not enduring a week's worth of itchiness, though I can't be certain.
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But her silicone injections, which were implanted in a hotel room for $2,000, left her with pain, itchiness, discoloration, and indentation.
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I tried my best to ignore the itchiness of the grass, the itch to explore the what ifs of someone else.
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The itchiness has led to open sores on his body, sleep deprivation, hypertension and anxiety, Mr. Weaver said in the complaint.
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"When they eat foods, such as cantaloupe, watermelon, or banana, they have itchiness or soreness inside their throats and mouth," he says.
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And it's also good to remember that even though they may cause itchiness and creep you out, head lice don't spread disease.
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After experiencing continued "burning" pain and itchiness, he sought a Lyme literate doctor at the suggestion of people who went to his church.
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Other signs of fungal acne are itchiness, and that all the "zits" appear at once, or are in similar stages, according to Friedman.
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If it's itchiness that's bothering you, try a warm compress — it'll help with the itching, and draw out any pus in the pimples.
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She is very good at whispering in your ear; she's good at embodying the itchiness of sitting in bed while suffering a crush.
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Patients should also be on the lookout for pain, rashes, itchiness, firmness, masses or changes in the size and shape of the breast.
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You should also be on the lookout for other symptoms, like discharge or itchiness, because those can also be signs of an infection.
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If allergies are behind your pink eye, you can use eye drops to help with the itchiness, and try to avoid your triggers.
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Always dreading running the mile, the itchiness of swimming laps in a bromine pool, and swiping deodorant all over my body before class.
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One buyer shared a story of having used Dawn for a while, but they switched to J.R. Watkins after experiencing redness and itchiness.
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For instance, if you're allergic to the gold in your necklace, you're probably going to experience some itchiness and redness near your neck.
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" "I personally struggle with sleep deprivation due to constant, widespread itchiness that feels more like I'm being stung or bitten then I am 'itchy.
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Along with itchiness and odor, common symptoms include a gray or white discharge and a burning feeling when you pee (similar to a UTI).
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That makes immune cells pump out molecules that cause itchiness and swelling, like histamine — the molecule blocked by over-the-counter allergy medications like Benadryl.
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And you know...we kind of believe her after seeing her beet-red face and hearing complaints about the severe itchiness while removing the mask.
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But the condition can cause a burning sensation when you pee, itchiness around your vagina, and white or gray discharge that has a fishy smell.
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My friend told me I was trying too hard to change everyone's mood through the music when I should instead celebrate our shared cerebral itchiness.
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If you're always rubbing your eyes (I'm guilty of it) the Klorane Smoothing and Relaxing Patches with Soothing Cornflower provide relief from dryness and itchiness.
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Sulfites are preservatives that can cause symptoms including itchiness, upset stomach, headache, stiffness, diarrhea, cough, nausea and weakness, according to the announcement on the FDA website.
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Itchiness and unsightly pilling are two of the most common things that make many pieces of cashmere uncomfortable and annoying to wear rather than a luxury.
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I once spent three sleepless nights tortured by intense itchiness until a dermatologist prescribed medication for what turned out to be an invasion of bird mites.
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I know the warming properties of wool really aren't worth it to me, when you weigh that against the itchiness and the smell when it gets damp.
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There are dozens of causes of itchiness, yet despite its banality it remains notoriously difficult to classify its cellular mechanisms of action, and as a result, treat.
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About 93% of cases with a known medical outcome caused no health effects, and another 82% caused only minor issues like redness or itchiness in the eyes.
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They're also easy to move around to any spots where bugs seems to be a bit more prevalent, making them a versatile tool for combating itchiness. OFF!
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The book features photos of real moms and plenty of advice to help women navigate everything from hyperpigmentation and excess itchiness to gender disappointment and that third boob.
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The risk, Dr. Zeichner explains, is that they can trigger contact dermatitis, with dryness, itchiness, and inflammation far outweighing the benefit of instant I'm-not-melting-anymore relief.
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As Donald Belsito, a professor of dermatology at Columbia University Medical Center in New York, told WSJ, new clothing often contains harmful chemicals that can cause rashes and itchiness.
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The rash got worse, with swelling and extreme itchiness, until the woman went to a dermatologist and was prescribed two anti-allergy and anti-inflammation medicines for two weeks.
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That last part, the hypopharynx, with the saliva is the one that causes the itchiness and is the one that delivers deadly viruses and parasites like Zika and Malaria.
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"It can be soothing for the itchiness and the camphor will also reduce the redness," says Dr. Green, but she stresses not to use it on open wounds or blisters.
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It has pyrithione zinc to treat dandruff and seborrheic dermatitis, while tea-tree oil and eucalyptus extract work to soothe itchiness and make your bathroom smell like you're at a spa.
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And speaking of carrying around — Beyoncé might prefer to keep hot sauce in her bag, but I'm pretty sure I'll be keeping this in all my purses for when itchiness strikes.
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The most telling sign, says Iris Looi, a physician assistant at the Russak Dermatology Clinic in Manhattan, is itchiness and sudden onset—as in, it's a new condition that you're experiencing.
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The sensation of itchiness, which is perceived by some of the same skin receptors that are on the lookout for pain, may seem like a purely physical phenomenon, but it's not.
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I&aposm borderline allergic to wool, but every part of the coat that would come into contact with my skin has some sort of liner to prevent any and all itchiness.
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And that's a long list of possibilities: Burning when you pee may be a result of a yeast infection, which causes irritation and itchiness (read: more irritation) around the vagina and vulva.
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With a 360 thread count, the companies swear you won't deal with any annoying itchiness as you fall asleep, and the 100% cotton will keep you cool during those hot summer nights.
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She described the microneedles as minuscule enough to not cause as much pain as a traditional flu shot; however, collectively, they were associated with itchiness at the injection site in the trial.
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The enzyme, she says, can exfoliate sensitive skin without causing redness, itchiness or flakiness because unlike traditional exfoliators, it dissolves only dead skin cells: It stops working when it encounters living tissue.
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But although many still think of the chickenpox as a mild, no-big-deal childhood illness, the truth is that this very contagious infectious disease can go beyond the rash, itchiness and fever.
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"If this were the culprit, there would typically be other symptoms associated with your nipple itchiness, such as changes in the architecture of the surrounding skin, pain or tenderness, or nipple inversion," she explains.
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Less Common Causes Midcalf points out that there are also less common explanations for vulva itchiness, including skin conditions such as eczema, lichen sclerosus, or lichen planus, and, rarely, malignancy such as vulval cancer.
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Some have likened it to pain, and while both pain and itchiness are unpleasant sensations, they result in opposite responses: a painful area will result in a withdrawal reflex whereas itching leads to scratching.
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Built around a sample of Forest Whitaker's dialogue from Ghost Dog: The Way of the Samurai, it's a solitary sort of experience, with twitchy percussion and yearning vocals echoing with the itchiness of outsiderdom.
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In the meantime, Liedtke hopes to probe deeper into the nature of cell-to-cell interactions in the skin, which will lead to improvements in personalized medicine and possible solutions for generalized long term itchiness.
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In the United States alone, nearly 31.6 million people suffer from eczema – which is defined as inflamed, rough blisters on the skin that cause severe itchiness (and anyone can get) – at some point in their lives.
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Here, like at most salons and spas I saw in the area, ratus is on the menu—a popular Indonesian steam treatment that claims to rid the vagina of odors, discharge, and itchiness using charcoal and herbs.
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Doctors still aren't completely sure why, but for people with PMLE, ultraviolet light from the sun stimulates an immune response that includes inflammation, swelling, itchiness, and a variety of rashes, including tiny blisters and raised, plaque-like skin.
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Remarkably, the team found that those mice with reduced TRPV4 sensitivity were less liable to scratch themselves when exposed to the chemicals, suggesting that TRPV4 plays a critical role in conveying the sensation of itchiness to the brain.
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More importantly, by isolating this particular protein as the gateway to the molecular path that ultimately leads to reflexive scratching, the team hopes that this will allow for the production of drugs which lower sensitivity to sensations of itchiness.
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The inmate, Calvin E. Weaver, 73, filed a lawsuit against the prison system in May, claiming that its employees violated his civil rights by ignoring his frequent complaints about relentless itchiness and resulting health problems caused by the blanket.
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It comes with the classic itchiness of a yeast infection and sometimes even the hallmark burning pee of a urinary tract infection (UTI), so it's understandable that so many of us mistake BV for those other more well-known issues.
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That includes bacterial vaginosis, a common vaginal infection that leads to itchiness and discharge; and toxic shock syndrome, a very rare but serious complication that causes a rash and flu-like symptoms, and if it progresses, can lead to renal failure or death.
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There's a lot to like about this new formula: The blend of peppermint, tea tree, and spearmint oils soothes itchiness and irritation on contact, while charcoal helps nix "impurities," which I interpret as the layers of dry shampoo built up on my hair follicles.
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You've probably heard of tea tree as an alternative to acne-fighting ingredients like salicylic acid or benzoyl peroxide, but if you've noticed the essential oil finding its way into shampoos and scalp treatments, then you've picked up on what's poised to become the next big thing when it comes to treating flakes and itchiness.
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And I use ingredients such as vinegar because it's antibacterial and so good against the dandruff; lemon, it's an acid PH that works so well to lock the artificial pigment inside your hair and to bring a natural shine; lavender calms down the scalp when you have itchiness; sage is the best thing against perspiration; chamomile is the best way to lift the hair in a gentle way.
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The itchiness may be helped by draining the gallbladder or ursodeoxycholic acid.
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They are usually not associated with any other symptoms although can sometimes cause itchiness or irritation.
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While the causes of itchiness are poorly understood, some evidence indicates that IL-2 is involved in itchy psoriasis.
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Rifampicin is used to treat itchiness caused by primary biliary cholangitis. The treatment-related adverse effects include hepatotoxicity, nephrotoxicity, hemolysis, and interactions with other drugs. For those reasons as well as some ethical concerns regarding off-label use of antibiotics, rifampin as a very effective preventive antibiotic for meningitis, is not considered appropriate for itchiness.
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Oclacitinib is labeled to treat atopic dermatitis and itchiness (pruritus) caused by allergies in dogs, though it has also been used to reduce the itchiness and dermatitis caused by flea infestations. It is considered to be highly effective in dogs, and has been established as safe for at least short-term use. Its efficacy equals that of prednisolone at first, though oclacitinib has been found to be more effective in the long term in terms of itchiness and dermatitis. It has been found to have a faster onset and cause less gastrointestinal issues than cyclosporine.
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In rare cases, exposure to the eye may result in eye irritation. Skin exposure to the sap may cause itchiness, redness, or swelling.
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This will loosen debris and remove dried scabs. Epsom-salt compresses applied twice daily dry the affected area to relieve the inflammation and itchiness.
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Urticaria and flushing on the back of a person with anaphylaxis Symptoms typically include generalized hives, itchiness, flushing, or swelling (angioedema) of the afflicted tissues. Those with angioedema may describe a burning sensation of the skin rather than itchiness. Swelling of the tongue or throat occurs in up to about 20% of cases. Other features may include a runny nose and swelling of the conjunctiva.
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Treatment involves not using topical steroids. These can either be stopped gradually or suddenly. Counselling and cold compresses may also help. Antihistamines may help for itchiness.
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Approximately 280 million people globally, 4% of the population, have difficulty with itchiness. This is comparable to the 2–3% of the population suffering from psoriasis.
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A Phase III clinical trial was carried out in 2010 to evaluate the effectiveness of bepotastine besilate ophthalmic solutions 1.0% and 1.5%. These solutions were compared to a placebo and evaluated for their ability to reduce ocular itchiness. The study was carried out with 130 individuals and evaluated after 15 minutes, 8 hours, or 16 hours. There was a reduction in itchiness at all- time points for both ophthalmic solutions.
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They have been known to bite humans if handled. Verified bites have caused no major medical problems. Localized itchiness at the bite site has been reported in some cases.
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Scalp pruritus is an itchiness of the scalp, particularly common in elderly persons.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
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A skin tag may remain after healing. If hemorrhoids are large and cause issues with hygiene, they may produce irritation of the surrounding skin, and thus itchiness around the anus.
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Pruritus scroti is itchiness of the scrotum that may be secondary to an infectious cause.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
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Use as a volume expander is not recommended. It is given by slow injection into a vein. Side effects include nausea and itchiness. Rarely there may be allergic reactions, blood clots, or infections.
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This results in rhinorrhea, itchiness, dyspnea, and anaphylaxis. Depending on the individual, the allergen, and the mode of introduction, the symptoms can be system-wide (classical anaphylaxis), or localized to particular body systems.
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Drug-induced pruritus is itchiness of the skin caused by medication, a pruritic reaction that is generalized.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
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Severe side effects include liver problems and allergic reactions. Liver injury is, however, unusual. Use during pregnancy is not typically recommended. The cream and ointment may result in itchiness but are generally well tolerated.
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HIV-associated pruritus is a cutaneous condition, an itchiness of the skin, that occurs in up to 30% of HIV infected people, occurs when the T-cell count drops below 400 per cubic mm.
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Formication may sometimes be experienced as feelings of itchiness, tingling, pins and needles, burning, or even pain. When formication is perceived as itchiness, it may trigger the scratch reflex, and because of this, some people who experience the sensation are at risk of causing skin damage through excessive scratching. In some instances, static electricity can attract particulates to the skin and can also cause body hair to move, giving a sensation like insects crawling over the skin. However, in many cases no external trigger creates the sensation.
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Pruritus vulvae is itchiness of the vulva, which is the counterpart of pruritus scroti, and may have many different causes.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
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It is taken by mouth. Common side effects include itchiness, hair loss, swelling, vomiting, muscle pains, numbness, and headache. Other severe side effects include liver problems and low blood cell counts. Use during pregnancy may harm the baby.
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Side effects include nausea, vomiting, abdominal pain, constipation, and itchiness. Rarely, dizziness, skin rash, drowsiness, perianal itching, or an unpleasant taste occur. For some of these reasons, praziquantel is a preferable and equally effective treatment for tapeworm infestation.
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Common side effects when applied on the skin include acne, skin atrophy, and itchiness. It works by decreasing inflammation. Mometasone furoate was patented in 1981 and came into medical use in 1987. It is available as a generic medication.
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Contact dermatitis occurs when the skin comes into contact with chemicals that cause a reaction, often redness, swelling or itchiness. Flood water often contains chemicals from industries or households that can cause such a reaction, these include pesticides, bleach and detergents.
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It is generally well tolerated. Common side effects include nausea, itchiness, rash, and trouble sleeping. Other side effects include allergic reactions and reactivation of hepatitis B among those previously infected. Use is not recommended in those with significant liver problems.
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Ketotifen relieves and prevents eye itchiness and/or irritation associated with most seasonal allergies. It starts working within minutes after administering the drops. The drug has not been studied in children under three. The mean elimination half life is 12 hours.
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Cyanocobalamin is generally well tolerated. Minor side effects may include diarrhea and itchiness. Serious side effects may include anaphylaxis, low blood potassium, and heart failure. Use is not recommended in those who are allergic to cobalt or have Leber's disease.
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Common side effects include low blood sugar, problems at the site of injection, itchiness, and weight gain. Serious side effects include low blood potassium. As of 2012 tentative evidence shows no association between insulin glargine and cancer. Previous studies had raised concerns.
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Common side effects include itchiness and rash at the site of application, headache, and nausea. Long term use may result in increased growth of fungi. Use during pregnancy and breastfeeding appears to be safe. Mupirocin is in the carboxylic acid class of medications.
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Side effects include nausea, vomiting, abdominal pain, and itchiness. It may be used during pregnancy and appears to be safe for the baby. Niclosamide is in the anthelmintic family of medications. It works by blocking the uptake of sugar by the worm.
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Side effects include diarrhea, constipation, skin rashes, hair loss, and itchiness. Because malaria tends to be more severe in pregnancy, the benefit typically outweighs the risk. If used during pregnancy it should be taken with folate. It is likely safe for use during breastfeeding.
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Generally a longer-acting insulin like NPH is also needed. Common side effects include low blood sugar, allergic reactions, itchiness, and pain at the site of injection. Other serious side effects may include low blood potassium. Use in pregnancy and breastfeeding is generally safe.
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Dandruff is a skin condition that mainly affects the scalp. Symptoms include flaking and sometimes mild itchiness. It can result in social or self-esteem problems. A more severe form of the condition, which includes inflammation of the skin, is known as seborrhoeic dermatitis.
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Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficulties and addiction. Whether its use in pregnancy is safe is unclear. Care should be used during breastfeeding, as it may result in opiate toxicity in the baby.
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It is taken by mouth once daily for typically 12 weeks. Common side effects include feeling tired, headache, rash, itchiness, and sensitivity to sunlight. In those with previous hepatitis B infection, active disease may recur. It is not recommended in those with significant liver problems.
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They include vomiting, skin flushing, headache, itchiness, and low blood pressure. Rare side effects include seizures and allergic reactions. It should not be used by those who have an iodine allergy. Iotroxic acid is an iodine containing contrast media of the diionic dimer type.
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These bites lead to skin lesions and itchiness, which is a nuisance to humans. While bedbugs are not known for being biological vectors of disease, there is evidence to suggest they can be vectors of Trypanosoma cruzi, a protist that causes Chaga's disease in humans.
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Seattle (WA): University of Washington, Seattle; 1993-2016. They may have diarrhoea, stomach pain, vomiting, or poor growth, a sign of malabsorption. They may have signs of bile duct problems, like itchiness, jaundice, pale stool, or dark urine. Their feces may be excessively greasy.
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When the mites come into contact with human skin, they attempt to feed there, causing an intense itchiness, often over the whole body surface. After about sixteen hours, blister-like vesicles erupt on the skin surface and other symptoms can include headache, joint pain, fever and nausea.
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One observed side effect is itchiness, suspected to be from the fleas dislodging. In the five hours after the treatment it was observed that cats were grooming themselves more, i.e scratching, biting, licking, and twitching. This will stop when the fleas have either flagged or have died.
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Side effects can include joint pain, sleepiness, headaches, depression, trouble sleeping, and itchiness. Severe side effects may include depression, psychosis, or osteonecrosis. In those with a history of epilepsy, it may increase the frequency of seizures. Greater care should also be taken in those with kidney problems.
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Vulvar cancer is a cancer of the vulva, the outer portion of the female genitals. It most commonly affects the outer vaginal lips. Less often, the inner vaginal lips, clitoris, or vaginal glands. Symptoms include a lump, itchiness, changes in the skin, or bleeding from the vulva.
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Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. Common side effects when used in the eyes include itchiness, redness, and a dry mouth.
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Common side effects include low blood sugar, problems at the site of injection, itchiness, and weight gain. Other serious side effects include low blood potassium. NPH insulin rather than insulin glargine is generally preferred in pregnancy. After injection microcrystals slowly release insulin for about 24 hours.
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Cheyletiella blakei is a small mite and ectoparasitic of domestic cats. It is a zoonosis that can be transmitted from the cat to humans. Its symptoms in human can include dermatosis, extreme 'itchiness'. Those who are most susceptible are people who have close contact with cats.
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When bitten, humans experience itchiness, wheals, and lesions around the affected areas on the skin. This species typically resides in human domiciles within cracks, crevices, or mattresses, and are more prevalent in developing countries. Like other bed bugs, C. hemipterus is primarily active during the night time.
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Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions. It is not recommended in people who have an iodine allergy. Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality. Diatrizoate was approved for medical use in the United States in 1954.
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Other conditions that may appear similar include cellulitis, contact dermatitis, and severe allergic reactions such as anaphylaxis. Treatment is often with a corticosteroids. Steroids applied as a cream is generally recommended over the use of steroids by mouth. Antihistamines may be used to help with itchiness.
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Common side effects when taken by mouth include loss of appetite, vomiting, abdominal pain, and diarrhea. When applied to the skin side effects include itchiness, redness, and blisters. When given by injection there may be fever, liver problems, or hearing loss. Use during breastfeeding appears to be safe.
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Anal cancer is a cancer which arises from the anus, the distal opening of the gastrointestinal tract. Symptoms may include bleeding from the anus or a lump near the anus. Other symptoms may include pain, itchiness, or discharge from the anus. A change in bowel movements may also occur.
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Altman and Mehregan described six characteristic features of ILVEN: (1) early age of onset, (2) predominance in females (4:1 female-male ratio), (3) frequent involvement of the left leg, (4) pruritus, or "itchiness" (5) marked refractoriness to therapy, and (6) a distinctive psoriasiform and inflammatory histologic appearance.
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The signs and symptoms of non-Hodgkin lymphoma vary depending upon its location within the body. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. Other symptoms may include bone pain, chest pain, or itchiness. Some forms are slow growing, while others are fast growing.
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A food allergy is an abnormal immune response to food. The symptoms of the allergic reaction may range from mild to severe. They may include itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, or low blood pressure. This typically occurs within minutes to several hours of exposure.
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Common side effects include abdominal pain, vomiting, diarrhea, cough, and itchiness. Serious side effects may include anaphylaxis, Stevens–Johnson syndrome, hallucinations, and liver problems. It is unclear if use during pregnancy or breastfeeding is safe for the baby. It is not recommended to prevent malaria in those with poor kidney function.
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A food allergy is an abnormal immune response to proteins in food. The signs and symptoms may range from mild to severe. They may include itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, or low blood pressure. These symptoms typically occurs within minutes to one hour after exposure.
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Non-Hodgkin lymphoma (NHL) is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss and tiredness. Other symptoms may include bone pain, chest pain or itchiness. Some forms are slow-growing, while others are fast-growing.
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Adverse events include any injury caused by the vaccine. Rarely, a cat will have an allergic reaction to a vaccine. This may include facial itchiness, or be a generalized allergic reaction that includes vomiting, diarrhea, breathing difficulties, and extremely rarely, collapse. Should any of these occur, contact your veterinarian immediately.
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Cases of icthyosis and skin dryness are also reported in response to this drug (8%-28%), as well as rash and itchiness (1-5%). 40-50% of patients develop gastrointestinal intolerance. Rarely, patients have died from bowel obstructions and intestinal bleeding, or required abdominal surgery to correct the same problem.
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A 2015 AHRQ review of treatments for insomnia had similar findings. A 2010 review found that topical doxepin is useful to treat itchiness. A 2010 review of treatments for chronic hives found that doxepin had been superseded by better drugs but was still sometimes useful as a second-line treatment.
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Calamine lotion, used to treat mild itchiness, is chiefly composed of a combination of zinc oxide, acting as astringent, and about 0.5% iron(III) oxide, the product's active ingredient, acting as antipruritic. The red color of iron(III) oxide is also mainly responsible for the lotion's widely familiar pink color.
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Common side effects include redness, itchiness, and pain at the site of use. Severe side effects may include vomiting, abdominal pain, confusion, bone marrow suppression, and diarrhea. It is not recommended for more than a small area at a time. Use during pregnancy is known to be dangerous to the baby.
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Atrophic vaginitis is inflammation of the vagina as a result of tissue thinning due to not enough estrogen. Symptoms may include pain with sex, vaginal itchiness or dryness, and an urge to urinate or burning with urination. It generally does not resolve without ongoing treatment. Complications may include urinary tract infections.
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Benadryl-brand diphenhydramine tablets Diphenhydramine is a first-generation antihistamine used to treat a number of conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as lidocaine.
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Peanut allergy is a type of food allergy to peanuts. It is different from tree nut allergies, with peanuts being legumes and not true nuts. Physical symptoms of allergic reaction can include itchiness, hives, swelling, eczema, sneezing, asthma attack, abdominal pain, drop in blood pressure, diarrhea, and cardiac arrest. Anaphylaxis may occur.
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Most people infected with C. trachomatis are asymptomatic. However, the bacteria can present in one of three ways: genitourinary (genitals), pulmonary (lungs), and ocular (eyes). Genitourinary cases can include genital discharge, vaginal bleeding, itchiness (pruritus), painful urination (dysuria), among other symptoms. Often, symptoms are similar to those of a urinary tract infection.
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Common side effects include blurry vision, redness of the eye, itchiness, and darkening of the iris. Latanoprost is in the prostaglandin analogue family of medication. It works by increasing the outflow of aqueous fluid from the eyes through the uveoscleral tract. Latanoprost was approved for medical use in the United States in 1996.
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Common side effects are belching, bloating, stomach discomfort or upset, nausea, vomiting, indigestion, dizziness, and flushing. Uncommon and rare side effects include angina, palpitations, hypersensitivity, itchiness, rash, hives, bleeding, hallucinations, arrhythmias, and aseptic meningitis. Contraindications include intolerance to pentoxifylline or other xanthine derivatives, recent retinal or cerebral haemorrhage, and risk factors for haemorrhage.
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Hydroxyzine, sold under the brand names Atarax and others, is a medication of the antihistamine type. It is used in the treatment of itchiness, anxiety, and nausea, including that due to motion sickness. It is used either by mouth or injection into a muscle. Common side effects include sleepiness, headache, and a dry mouth.
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Other medications used for AD include systemic immunosuppressants such as ciclosporin, methotrexate, interferon gamma-1b, mycophenolate mofetil and azathioprine. Antidepressants and naltrexone may be used to control pruritus (itchiness). In 2017, the biologic agent dupilumab was approved to treat moderate-to-severe eczema. Leukotriene inhibitors such as monteleukast are of unclear benefit as of 2018.
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Common side effects include itchiness, hair loss, nausea, muscle pain, swelling, and abdominal pain. Severe side effects may include low blood cell counts, liver failure, and vasculitis. Use is not recommended during the first trimester of pregnancy but may be used in the second trimester or third trimester. It may be used during breastfeeding.
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Commonly observed side-effects, occurring in 1 to 10% of cases, include stool discoloration, diarrhea, nausea, and dyspepsia. Uncommon side-effects, occurring in 0.1 to 1% of cases, include constipation, vomiting, stomachache, tooth discoloration, itchiness, and headache. As very rare side-effects, occurring in 0.1 to 0.01% of cases, allergic reactions have been observed.
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Ear pain can present in one or both ears. It may or may not be accompanied by other symptoms such as fever, sensation of the world spinning, ear itchiness, or a sense of fullness in the ear. The pain may or may not worsen with chewing. The pain may also be continuous or intermittent.
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Overview of the most significant symptoms of diabetes. The classic symptoms of diabetes are frequent urination (polyuria), increased thirst (polydipsia), increased hunger (polyphagia), and weight loss. Other symptoms that are commonly present at diagnosis include a history of blurred vision, itchiness, peripheral neuropathy, recurrent vaginal infections, and fatigue. Other symptoms may include loss of taste.
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Common side effects by mouth include tiredness, slow heart beat, itchiness, and shortness of breath. Other side effects include masking the symptoms of low blood sugar in those with diabetes. Use is not recommended in those with asthma, uncompensated heart failure, or COPD. It is unclear if use during pregnancy is safe for the baby.
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Lenalidomide, sold under the trade name Revlimid among others, is a medication used to treat multiple myeloma (MM) and myelodysplastic syndromes (MDS). For MM it is used after at least one other treatment and generally together with dexamethasone. It is taken by mouth. Common side effects include diarrhea, itchiness, joint pain, fever, headache, and trouble sleeping.
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Itchiness or pain around the anus may be suggestive of inflammation, fistulization or abscess around the anal area or anal fissure. Perianal skin tags are also common in Crohn's disease, and may appear with or without the presence of colorectal polyps. Fecal incontinence may accompany perianal Crohn's disease. The mouth may be affected by recurrent sores (aphthous ulcers).
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Wilson's disease is a genetic disorder in which excess copper builds up in the body. Symptoms are typically related to the brain and liver. Liver-related symptoms include vomiting, weakness, fluid build up in the abdomen, swelling of the legs, yellowish skin and itchiness. Brain-related symptoms include tremors, muscle stiffness, trouble speaking, personality changes, anxiety, and psychosis.
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It is also available as the combinations bacitracin/polymyxin B and neomycin/polymyxin B/bacitracin for use on the skin. Common side effects when given by injection include kidney problems, neurological problems, fever, itchiness, and rash. Injections into muscle may result in significant pain. Other serious side effects may include fungal infections, anaphylaxis, and muscle weakness.
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While safe in the short term, oclacitinib's long-term safety is unknown. While some say it is best only for acute flares of itchiness, others claim that it is also useful in chronic atopic dermatitis. There is some off-label use of oclacitinib in treating asthma and allergic dermatitis in cats, but the exact efficacy has not been established.
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The plant is widely produced in China, Japan, and Korea. The species is edible by both animals and humans alike, due to its high levels of nutrients and good taste. It is also used in various cosmetics to prevent skin itchiness. It is used as fertilizer because it adds a wide range of minerals to the soil.
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Common side effects include trouble sleeping, nausea, itchiness, and feeling tired. It is not recommended in those with liver failure but appears okay in people with kidney disease. While there is no evidence of harm if used during pregnancy, it has not been well studied. It should not be used with birth control pills that contain ethinylestradiol.
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Low blood pressure #: d. Gastrointestinal symptoms # Low blood pressure after exposure to a known allergen Skin involvement may include: hives, itchiness or a swollen tongue among others. Respiratory difficulties may include: shortness of breath, stridor, or low oxygen levels among others. Low blood pressure is defined as a greater than 30% decrease from a person's usual blood pressure.
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Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. It is used as an ear drop or eye drop. The most common side effects include itchiness and a skin rash.
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Common side effects include abdominal pain, diarrhea, itchiness, dry skin, and change in color of the skin. May also cause swelling of the lining of the gastrointestinal tract, increased blood sugar, and sensitivity to the sun. It is unclear if use during pregnancy is safe. Clofazimine is a phenazine dye and believed to work by interfering with DNA.
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When used by mouth, side effects include shortness of breath, headache, numbness, depression, skin dryness, itchiness, hair loss, vomiting, muscle pains, and vision changes. Other severe side effects include high white blood cell counts and blood clots. Use during pregnancy is contraindicated due to the risk of birth defects. It is in the retinoid family of medications.
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Antihistamines can alleviate some of the milder symptoms of an allergic reaction, but do not treat all symptoms of anaphylaxis. Antihistamines block the action of histamine, which causes blood vessels to dilate and become leaky to plasma proteins. Histamine also causes itchiness by acting on sensory nerve terminals. The most common antihistamine given for food allergies is diphenhydramine.
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The allergens are not passed down through generations. It is believed if parents have allergies the child is more likely to be allergic to the same allergens. Some common symptoms include itchiness, swelling, running nose, watery eyes, coughing, wheezing, trouble breathing, hives, rashes, mucus production, or a more severe reaction anaphylaxis. Allergic responses and the severity vary from person to person.
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Genuine allergy to LA will manifest either as Type 1 or Type 4 hypersensitivity. Signs and symptoms will vary depending on the type of allergy. Type 1 reactions have a rapid onset of symptoms which include swelling, redness, rashes, itchiness, chest tightness, breathing problems. A Type 4 reaction has a delayed onset of symptoms and is usually localized to the site of injection.
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Most spider bites are managed with supportive care such as nonsteroidal anti-inflammatory drugs (including ibuprofen) for pain and antihistamines for itchiness. Opioids may be used if the pain is severe. While an antivenom exists for black widow spider venom, it is associated with anaphylaxis and therefore not commonly used in the United States. Antivenom against funnel web spider venom improves outcomes.
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In general, the clinical presentation of subcutaneous zygomycosis is quite identifiable and characteristic and the diagnosis is fairly easy. Human infection is characterized by the single formation of enlarging, painless and firm swelling in soft tissues on extremities e.g. buttocks, thighs, perineum, trunk. However, as the infection worsens, symptoms such a burning sensation or itchiness may develop in the swollen region.
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Red wasp stingers do not remain in their victims. A red wasp sting is often painful and causes localized swelling and itchiness. In some cases, people report developing a full-body, itchy rash. Applying a cold compress or ice to the area can help relieve swelling, while application of calamine lotion or 1% hydrocortisone cream can help relieve itching and pain.
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The condition was first distinguished in 1980. People with exercise urticaria (EU) experience hives, itchiness, shortness of breath and low blood pressure five to 30 minutes after beginning exercise. These symptoms can progress to shock and even sudden death. Jogging is the most common exercise to cause EU, but it is not induced by a hot shower, fever, or with fretfulness.
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One of the more serious side effects of cetuximab therapy is the incidence of acne-like rash. This rash rarely leads to dose reductions or termination of therapy. It is generally reversible. Further severe infusion reactions include but are not limited to: fevers, chills, rigors, urticaria, itchiness, rash, hypotension, nausea, vomiting, headache, shortness of breath, wheezing, angioedema, dizziness, anaphylaxis, and cardiac arrest.
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Another treatment option that has been met with success in small-scale trials is the application of a very mild (.006) topical capsaicin cream. This strength cream is not typically commercially available and therefore must be diluted by a pharmacist or end-user. If the itchiness is secondary to another condition such as infection or psoriasis these are typically treated.
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It's like 'Oh yeah. That's good! That's better!'" "What I think was surprising on him was that from all of the humor he's involved and his sort of itchiness that he has with Kat, there is some moments where he reveals how vulnerable he really is and so the shield comes down and right in there you're really becoming sympathetic to Rory.
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Doxepin is a medication used to treat major depressive disorder, anxiety disorders, chronic hives, and trouble sleeping. For label updates see FDA index page for NDA 022036 For hives it is a less preferred alternative to antihistamines. It has a mild to moderate benefit for sleeping problems. It is used as a cream for itchiness due to atopic dermatitis or lichen simplex chronicus.
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Scombroid food poisoning, also known as simple scombroid, is a foodborne illness that typically results from eating spoiled fish. Symptoms may include flushed skin, headache, itchiness, blurred vision, abdominal cramps, and diarrhea. Onset of symptoms is typically 10 to 60 minutes after eating and can last for up to two days. Rarely, breathing problems or an irregular heartbeat may occur.
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Dermatitis, also known as eczema, is a group of diseases that result in inflammation of the skin. These diseases are characterized by itchiness, red skin and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to covering the entire body.
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It is being investigated by Vanda Pharmaceuticals for chronic pruritus (itchiness) in atopic dermatitis. In March 2015, Vanda announced positive results from a Phase II proof of concept study. A proof of concept study is done in early stage clinical trials after there have been promising preclinical results. It provides preliminary evidence that the drug is active in humans and has some efficacy.
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As is typical of opioids, common side effects include constipation, itchiness, and nausea. Serious side effects may include seizures, increased risk of serotonin syndrome, decreased alertness, and drug addiction. A change in dosage may be recommended in those with kidney or liver problems. It is not recommended in those who are at risk of suicide or in those who are pregnant.
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Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. It may be used together with ondansetron and dexamethasone. It is taken by mouth. Common side effects include tiredness, loss of appetite, diarrhea, abdominal pain, hiccups, itchiness, pneumonia, and blood pressure changes.
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Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels. It is specifically used to prevent gout, prevent specific types of kidney stones and for the high uric acid levels that can occur with chemotherapy. It is taken by mouth or injected into a vein. Common side effects when used by mouth include itchiness and rash.
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Topical steroid withdrawal, also known as red burning skin and steroid dermatitis, has been reported in long-term users of topical steroids after they stop the use. Symptoms include redness of the skin, a burning sensation, and itchiness. This may then be followed by skin peeling. Itsan.org a reputable nonprofit are thought leaders in this area and work towards raising awareness and information for affected individuals.
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Bed bugs are insects from the genus Cimex that feed on human blood, usually at night. Their bites can result in a number of health impacts including skin rashes, psychological effects, and allergic symptoms. Bed bug bites may lead to skin changes ranging from small areas of redness to prominent blisters. Symptoms may take between minutes to days to appear and itchiness is generally present.
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Internal hemorrhoids usually present with painless, bright red rectal bleeding during or following a bowel movement. The blood typically covers the stool (a condition known as hematochezia), is on the toilet paper, or drips into the toilet bowl. The stool itself is usually normally coloured. Other symptoms may include mucous discharge, a perianal mass if they prolapse through the anus, itchiness, and fecal incontinence.
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In women, 81.3% of EMPD cases are related to the vulva, while for men, 43.2% of the manifestations present at the scrotum. The disease can be classified as being either primary or secondary depending on the presence or absence of associated malignancies. EMPD presents with typical symptoms such as scaly, erythematous, eczematous lesions accompanied by itchiness. In addition to this, 10% of patients are often asymptomatic.
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The Rongelap Atoll was coated with up to of snow-like irradiated calcium debris and ash over the entire island. Virtually all the inhabitants experienced severe radiation sickness, including itchiness, sore skin, vomiting, diarrhea, and fatigue. Their symptoms also included burning eyes and swelling of the neck, arms, and legs. They were forced to abandon the islands three days after the tests, leaving behind all their belongings.
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Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is a medication used to reduce the risk of infections following minor skin injuries and to treat superficial bacterial eye infections. It contains three antibiotics: neomycin, polymyxin B, and bacitracin. It is for topical use only and should not be ingested. Possible side effects include itchiness and skin rash, and in rare cases hearing loss.
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Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, pityriasis versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina. Common side effects when taken by mouth include nausea and itchiness.
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It usually lasts less than three months and goes away without treatment. Sometimes malaise or a fever may occur before the start of the rash or itchiness, but often there are few other symptoms. While the cause is not entirely clear, it is believed to be related to human herpesvirus 6 (HHV6) or human herpesvirus 7 (HHV7). It does not appear to be contagious.
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The left side of the image is showing the temperature increase caused by an insect bite after about 28 hours. Low- magnification micrograph showing wedge-shaped perivascular inflammation (superficial dermal perivascular lymphoeosinophilic infiltrate), the histomorphologic appearance of an insect bite (H&E; stain). The reaction to a sting is of three types. The normal reaction involves the area around the bite with redness, itchiness, and pain.
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A United States military medical team visited the island with geiger counters the day after the fallout, but left without telling the islanders of the danger they had been exposed to. Virtually all the inhabitants experienced severe radiation sickness, including itchiness, sore skin, vomiting, diarrhea, and fatigue. Their symptoms also included burning eyes and swelling of the neck, arms, and legs.Isobelle Gidley and Richard Shears (1986).
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Cats with miliary dermatitis have a rash consisting of fine papules surmounted by small crusts. Although most are unaffected by rash, where noticed a broad rash can be concentrated to the back of the neck, scapular (shoulder blade) and surrounding areas, and/or the lower abdomen and surrounding areas. Secondary infection with Staphylococcus intermedius is common. Signs include itchiness, "elevated grooming", and visible spots of fur-loss.
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Other diseases that must be excluded before making a diagnosis include contact dermatitis, psoriasis, and seborrheic dermatitis. Treatment involves avoiding things that make the condition worse, daily bathing with application of a moisturising cream afterwards, applying steroid creams when flares occur, and medications to help with itchiness. Things that commonly make it worse include wool clothing, soaps, perfumes, chlorine, dust, and cigarette smoke. Phototherapy may be useful in some people.
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Ciguatera fish poisoning (CFP), also known simply as ciguatera, is a foodborne illness caused by eating reef fish whose flesh is contaminated with certain toxins. Such individual fish are said to be ciguatoxic. Symptoms may include diarrhea, vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness, and weakness. The onset of symptoms varies with the amount of toxin eaten from half an hour to up to two days.
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There has only been one published case of infection caused by O. cereale. In 1969, a female clerk at the Skin Department of the Helsinki University Central Hospital reported itchiness on her neck. Near the nape of the neck, there was an archetypal presentation of neurodermitis nuchae, or more commonly known as atopic dermatitis. A sample was cultured from her neck and on all three occasions, O. cereale was present.
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Less common side effects of oclacitinib include bloody diarrhea; pneumonia; infections of the skin, ear, and/or urinary tract; and histiocytomas (benign tumors). Increases in appetite, aggression, and thirst have also been reported. Oclacitinib is more likely to cause side effects if given twice a day than if given once a day. Some dogs transitioning from twice-a-day to once-a-day dosing have gotten a temporary increase in itchiness.
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There is a reaction from consuming fish that mimics an allergic reaction. Scombroid is a foodborne illness that results from high in histamine due to inappropriate storage or processing. Histamine is the main natural chemical responsible for true allergic reactions, hence the confusion with fish allergy. Scombroid symptom onset is typically 10-30 minutes after consumption, and may include flushed skin, headache, itchiness, blurred vision, abdominal cramps and diarrhea.
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Common side effects include redness, itchiness, and pain at the site of injection. Allergic reactions may occasionally occur. The test may be falsely positive in those who have been previously vaccinated with BCG or have been infected by other types of mycobacteria. The test may be falsely negative within ten weeks of infection, in those less than six months old, and in those who have been infected for many years.
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Iohexol, sold under the trade name Omnipaque among others, is a contrast agent used during X-rays. This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computer tomography (CT scan). It is given by mouth, injection into a vein, or into a body cavity. Side effects include vomiting, skin flushing, headache, itchiness, kidney problems, and low blood pressure.
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Attachment of the nymphal and adult stages produce variable responses, many of which are clearly allergic in nature. Often, attachment may provoke little or no response and the patient may be quite unaware of the presence of a tick for some days until eventually minor itchiness leads to its discovery. Conversely, there is sometimes a locally heightened sensitivity or hyperaesthesia.Atwell R and Fitzgerald M (1994) Unsolved issues in tick paralysis.
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They are popular among collectors, but they tend to be highly defensive, lacking urticating hairs, and are not suitable for beginners. They have very strong venom, though none are known to be deadly to humans. A bite from a smaller spider will cause sharp pain and localized itchiness for five days. Adults can be kept in a converted aquarium if given plenty of ventilation and a substrate at least deep.
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They used wine along with boiled water and vinegar to cleanse wounds. The Greeks, specifically Hippocrates (430–377 BC), were also the first to establish the four cardinal signs of inflammation: redness, swelling, heat and pain. Alcohol is still in use today as a wound cleanser largely as rubbing alcohol. However the side effects can be skin cell death resulting in inflammation and itchiness at the site of application.
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Erythema ab igne (EAI), also known as hot water bottle rash, is a skin condition caused by long-term exposure to heat (infrared radiation). Prolonged thermal radiation exposure to the skin can lead to the development of reticulated erythema, hyperpigmentation, scaling and telangiectasias in the affected area. Some people may complain of mild itchiness and a burning sensation, but often, unless a change in pigmentation is seen, it can go unnoticed.
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Gardeners working with bamboo plants have occasionally reported allergic reactions varying from no effects during previous exposures, to immediate itchiness and rash developing into red welts after several hours where the skin had been in contact with the plant (contact allergy), and in some cases into swollen eyelids and breathing difficulties (dyspnoea). A skin prick test using bamboo extract was positive for the immunoglobulin E (IgE) in an available case study.
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If a bile duct blockage is present, surgery is typically required; otherwise, management is medical. Medical management may involve treating infectious causes and stopping medication that could be contributing to the jaundice. Jaundice in newborns may be treated with phototherapy or exchanged transfusion depending on age and prematurity when the bilirubin is greater than 4–21 mg/dl (68-360 µmol/l). The itchiness may be helped by draining the gallbladder or ursodeoxycholic acid.
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Changes in a mole that can indicate melanoma include an increase in size, irregular edges, change in color, itchiness or skin breakdown. The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of the skin pigment melanin. The UV light may be from the sun or other sources, such as tanning devices. Those with many moles, a history of affected family members and poor immune function are at greater risk.
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In people with shock, including septic, cardiogenic, hemorrhagic, or spinal shock, those who received naloxone had improved blood flow. The importance of this is unclear. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis, an extremely rare disorder that renders one unable to feel pain or differentiate temperatures. Naloxone can also be used to treat itchiness brought on by opioid use, as well as opioid-induced constipation.
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Opioids are frequently used non-medically for their euphoric effects or to prevent withdrawal. Side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria. Long- term use can cause tolerance, meaning that increased doses are required to achieve the same effect, and physical dependence, meaning that abruptly discontinuing the drug leads to unpleasant withdrawal symptoms. The euphoria attracts recreational use and frequent, escalating recreational use of opioids typically results in addiction.
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Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. It is used for ring worm of the body, groin (jock itch), and feet (athlete's foot). It is applied to the skin or vagina as a cream or ointment. Common side effects include itchiness or irritation of the area in which it was applied.
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Diseases affecting the rectum and anus are extremely common, especially in older adults. Hemorrhoids, vascular outpouchings of skin, are very common, as is pruritus ani, referring to anal itchiness. Other conditions, such as anal cancer may be associated with ulcerative colitis or with sexually transmitted infections such as HIV. Inflammation of the rectum is known as proctitis, one cause of which is radiation damage associated with radiotherapy to other sites such as the prostate.
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The most commonly reported adverse effects for IV formulations of acetylcysteine are rash, urticaria, and itchiness. Up to 18% of patients have been reported to experience anaphylaxis reaction, which are defined as rash, hypotension, wheezing, and/or shortness of breath. Lower rates of anaphylactoid reactions have been reported with slower rates of infusion. Adverse effects for inhalational formulations of acetylcysteine include nausea, vomiting, stomatitis, fever, rhinorrhea, drowsiness, clamminess, chest tightness, and bronchoconstriction.
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The drug label has warnings with regard to the risk of respiratory depression, anticholinergic toxicity and opioid overdose, the risk of dehydration and electrolyte imbalance that people with severe diarrhea always run, and toxic megacolon in people with ulcerative colitis. Other adverse effects include numbness in the hands and feet, euphoria, depression, lethargy, confusion, drowsiness, dizziness, restlessness, headache, hallucinations, edema, hives, swollen gums, itchiness, vomiting, nausea, loss of appetite, and stomach pain.
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Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis is by finding the parasite in a blood smear or in the fluid of a lymph node.
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Most symptoms of peanut allergy are related to the action of immunoglobulin E (IgE) and other anaphylatoxins which act to release histamine and other mediator substances from mast cells (degranulation). In addition to other effects, histamine induces vasodilation of arterioles and constriction of bronchioles in the lungs, also known as bronchospasm. Symptoms can also include mild itchiness, hives, angioedema, facial swelling, rhinitis, vomiting, diarrhea, acute abdominal pain, exacerbation of atopic eczema, asthma, and cardiac arrest. Anaphylaxis may occur.
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White-tailed spiders (Lampona spp.), indigenous to Australia and present as an invasive pest in New Zealand, have been blamed for a necrotic bite, producing symptoms similar to a brown recluse. The white-tailed spider (Lampona) was implicated for decades in necrotic lesions, but has been exonerated. A study of 130 white-tailed spider bites found no necrotic ulcers or confirmed infections; only a red mark, local swelling, and itchiness. Very occasionally nausea, vomiting, malaise or headache may occur.
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A medical use for a sauna suit is in the treatment of psoriasis, an inflammation of the skin causing itchiness and discomfort. The symptoms of psoriasis can be relieved by use of ointments and by keeping the skin moist. The wearing of a sauna suit helps to retain skin moisture and to prevent the ointment from leaking out and staining other clothing, furniture or bedding. In medical literature, a sauna suit is also called an "occlusion suit".
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The study concluded that bepotastine besilate ophthalmic formulations reduced ocular itchiness for at least 8 hours after dosing compared to placebo. Phase I and II trials were carried out in Japan. Studies have been performed in animals and bepotastine besilate was not found to be teratogenic in rats during fetal development, even at 3,300 times more that typical use in humans. Evidence of infertility was seen in rats at 33,000 times the typical ocular dose in humans.
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Menthogen topical scalp stimulantMenthogen is a topically applied scalp stimulant which is claimed by its manufacturers to treat itchiness and irritation of the scalp as well as combating certain types of alopecia.What is Menthogen, Official Menthogen UK web site, accessed 8 August 2010. Since its development (see history below) Menthogen has been further developed in the UK by a team of trichologists. Menthogen's scalp cooling effect occurs due to the presence of menthol and alcohol within the formula.
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Mucuna pruriens is a tropical legume native to Africa and tropical Asia and widely naturalized and cultivated. Its English common names include monkey tamarind, velvet bean, Bengal velvet bean, Florida velvet bean, Mauritius velvet bean, Yokohama velvet bean, cowage, cowitch, lacuna bean, and Lyon bean. The plant is notorious for the extreme itchiness it produces on contact, particularly with the young foliage and the seed pods. It has agricultural and horticultural value and is used in herbalism.
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In dermatology, topical clobetasone butyrate helps to reduce the itchiness and erythema associated with eczema and dermatitis. In ophthalmology, clobetasone butyrate 0.1% eye drops have been shown to be safe and effective in the treatment of dry eyes in Sjögren syndrome. Sjögren syndrome is an autoimmune disorder that affects the moisture producing glands of the body causing many symptoms including dry eyes. When compared to other corticosteroid eye drops; clobetasone butyrate showed only minimal rises in intraocular pressure.
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An eye wash station in a laboratory eyelash is a fluid, commonly salineus, used to physically wash the eyes in the case that they may be contaminated by foreign materials or substances. Eyewashes may be beneficial to those with sensitive eyes and can provide relief to the painful side effects of sensitivity. However, prolonged usage of such products will cause mild side effects, such as the reddening of the eye and/or pupil and cause itchiness.
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This causes vaginal discharge and itchiness of the vulva. The pinworms can also enter the urethra, and presumably, they carry intestinal bacteria with them. According to Gutierrez (2000), a statistically significant correlation between pinworm infection and urinary tract infections has been shown; however, Burkhart & Burkhart (2005) maintain that the incidence of pinworms as a cause of urinary tract infections remains unknown. One report indicated that 36% of young girls with a urinary tract infection also had pinworms.
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Custom-fitted surfer's earplugs help reduce the amount of cold water and wind that is allowed to enter the external ear canal and, thus, help slow the progression of exostosis. Another condition is otitis externa, which is an infection of the outer ear canal. This form of infection differs from those commonly occurring in children behind the eardrum, which is otitis media, or a middle ear infection. This infection's symptoms include: itchiness, redness, swelling, pain upon tugging of the pinna, or drainage.
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Sézary syndrome in a 61-year-old man presenting in 1972 with unrelenting itchiness of six months’ duration. On the right is his peripheral blood film stained with Periodic Acid-Schiff (PAS) showing a neoplastic T cell (Sézary cell). Those who have Sézary disease often present with skin lesions that do not heal with normal medication. A blood test generally reveals any change in the levels of lymphocytes in the blood, which is often associated with a cutaneous T-cell lymphoma.
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White-tailed spiders are vagrant hunters that seek out and envenom prey rather than spinning a web to capture it; their preferred prey is other spiders. They are reported to bite humans, with effects including a red mark, and local itchiness, swelling and pain. On rare occasions, bites can result in nausea, vomiting, malaise or headache. Although ulcers and necrosis have been attributed to the bites, a scientific study by Isbister and Gray (2003) showed they had other causes, mostly infections.
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Rivera was booed by some members of the crowd in her swimsuit, evening gown and final question competitions. Despite it all Rivera won the title, although her victory is portrayed as an unfair win. Three days after the pageant was over an even bigger controversy arouse when it was revealed Rivera's belongings had been stolen while the competition was undergoing. Also Rivera's gown and makeup had been coated with pepper spray, causing redness and itchiness in her skin during the pageant.
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Iguratimod is an anti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis, together with methotrexate in Japan and China. As of 2015 the biological target was not known, but it prevents NF-κB activation and subsequently selectively inhibits COX-2 and several inflammatory cytokines. Adverse effects include Elevated transaminases, nausea, vomiting, stomach pain; rashes, and itchiness. It is a derivative of 7-methanesulfonylamino-6-phenoxychromones and is a chromone with two amide groups; it was first published in 2000.
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Presentation can be atypical and without pain or fever, especially in the elderly. Positive symptoms include biliary colic, acute pancreatitis, obstructive jaundice and less commonly, liver enlargement and abnormal liver function tests. Additional complications in the acute setting include ascending cholangitis, gallbladder empyema, clotting within the hepatic and portal veins, sepsis and death. Chronic biliary obstruction may cause jaundice, itchiness, liver abscesses, and cirrhosis, particularly at the left lobe segment 3, and can eventually lead to intraductal papillary mucinous neoplasm or cholangiocarcinoma.
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Hydroxyzine is used in the treatment of itchiness, anxiety, and nausea due to motion sickness. A systematic review concluded that compared with other anxiolytic agents (benzodiazepines and buspirone), hydroxyzine was equivalent in efficacy, acceptability, and tolerability. Hydroxyzine can also be used for the treatment of allergic conditions, such as chronic urticaria, atopic or contact dermatoses, and histamine-mediated pruritus. These have also been confirmed in both recent and past studies to have no adverse effects on the liver, blood, nervous system, or urinary tract.
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Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and whites of the eyes due to high bilirubin levels. Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. The prevalence of jaundice in adults is rare, while jaundice in babies is common with an estimated 80% affected during their first week of life. The most commonly associated symptoms of jaundice are itchiness, pale feces, and dark urine.
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Int Arch Allergy Immunol 116:36-39 Consequently, suppressing the NF-κB limits the proliferation of cancer cells and reduces the level of inflammation. Avenanthramides are able to inhibit the release of inflammatory cytokines that are present in pruritic skin diseases that cause itchiness. In addition, its anti-inflammatory activity may prevent the vicious itch-scratch cycle and reduce the scratching-induced secondary inflammation that often occur in atopic dermatitis and eczema, preventing the skin from disrupting its barrier.Schmelz M., Handwerker H.O. (2003) "Neurophysiologic basis of itch".
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Blockage or obstruction of the bile duct by gallstones, scarring from injury, or cancer prevents the bile from being transported to the intestine and the active ingredient in the bile (bilirubin) instead accumulates in the blood. This condition results in jaundice, where the skin and eyes become yellow from the bilirubin in the blood. This condition also causes severe itchiness from the bilirubin deposited in the tissues. In certain types of jaundice, the urine will be noticeably darker, and the stools will be much paler than usual.
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Progesterone is well tolerated, and many clinical studies have reported no side effects. Side effects of progesterone may include abdominal cramps, back pain, breast tenderness, constipation, nausea, dizziness, edema, vaginal bleeding, hypotension, fatigue, dysphoria, depression, and irritability, among others. Central nervous system depression, such as sedation and cognitive/memory impairment, can also occur. Vaginal progesterone may be associated with vaginal irritation, itchiness, and discharge, decreased libido, painful sexual intercourse, vaginal bleeding or spotting in association with cramps, and local warmth or a "feeling of coolness" without discharge.
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Side effects may be mild such as itchiness, folliculitis, sunburn, poikiloderma, and a theoretical risk of nonmelanoma cancer or melanoma has been suggested. Some studies indicate no increased risk of melanoma in the long term. Data are inconclusive with respect to nonmelanoma skin cancer risk, but support the idea that the therapy is associated with an increased risk of benign forms of sun-induced skin damage such as, but not limited to, actinic elastosis or liver spots. Dead Sea balneotherapy is also effective for psoriatic arthritis.
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The common adverse reactions have been fatigue (24%), rash (19%), itchiness (pruritus) (17%), diarrhea (12%), nausea (11%) and joint pain (arthralgia) (10%). Other adverse effects occurring in between 1% and 10% of people taking pembrolizumab have included anemia, decreased appetite, headache, dizziness, distortion of the sense of taste, dry eye, high blood pressure, abdominal pain, constipation, dry mouth, severe skin reactions, vitiligo, various kinds of acne, dry skin, eczema, muscle pain, pain in a limb, arthritis, weakness, edema, fever, chills, myasthenia gravis, and flu-like symptoms.
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Common side effects include worsening of acne, increased sensitivity to sunlight, dry skin, itchiness, redness and in some cases extreme drying and cracking of skin. For most patients these side effects are uncomfortable but mild and decrease markedly after the first 2–4 weeks of use except for increased sensitivity to sunlight. For best results dermatologists recommend applying the cream or gel once daily before bedtime after washing the face with a mild cleanser. Dermatologists recommend using a moisturizer so that skin will not be as dry and flaky.
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A 4-year-old boy with icteral sclerae due to G6PD deficiency The most common signs of jaundice in adults are a yellowish discoloration of the white area of the eye (sclera) and skin with scleral icterus presence indicating a serum bilirubin of at least 3 mg/dl. Other common signs include dark urine (bilirubinuria) and pale,(acholia) fatty stool (steatorrhea). Because bilirubin is a skin irritant, jaundice is commonly associated with severe itchiness. Eye conjunctiva have a particularly high affinity for bilirubin deposition due to high elastin content.
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Unlike other forms of ear infections, the pain of acute external otitis is worsened when the outer ear is touched or pulled gently. Pushing the tragus, the tablike portion of the auricle that projects out just in front of the ear canal opening, also typically causes pain in this condition as to be diagnostic of external otitis on physical examination. People may also experience ear discharge and itchiness. When enough swelling and discharge in the ear canal is present to block the opening, external otitis may cause temporary conductive hearing loss.
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In addition to the risk of causing birth defects and of causing liver damage, bosentan has a high risk of causing edema, pulmonary veno-occlusive disease, decreasing sperm counts, and decreases in hemoglobin and hematocrit. Very common adverse effects (occurring in more than 10% of people) include headache, elevated transaminases, and edema. Common adverse effects (between 1% and 10% of people) include anemia, reduced hemoglobin, hypersensitivity reactions, skin inflammation, itchiness, rashes, red skin, flushing, fainting, heart palpitations, low blood pressure, nasal congestion, gastro-esophageal reflux disease, and diarrhea.
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The diagnosis, which may be difficult to distinguish form other skin disorders, is based on history of mosquito bites and previous or concurrent predisposing diseases, the course taken by the skin lesions, and the pathology of these lesions. Blood eosinophil levels are elevated in about half of these cases. The disorder has generally been either untreated or treated with short- or longer-term oral glucocorticoids, topical glucorocoricoids, and/or injections of glucocorticoids into the skin lesions, depending or lesion severities. Oral antihistamines are used to alleviate any associated itchiness.
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Adrenaline (also called epinephrine) can quickly reverse the adverse events of dyspnoea and hypotension It is suggested that a conservative approach be used when treating sting injuries; specifically, the kind of treatment used should be based on the symptoms. For minor sting injuries, with symptoms only including pustule formations and pain, over-the-counter products are available to prevent infection. Ants should be removed by washing the area with antiseptic soap, and itchiness. It is rare for ant sting sites to become infected, so the use of antibiotic prophylaxis is not always required.
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Juveniles tend to have more or less obvious whitish marks on the upper surface of the abdomen. The urban myth originated in 1982 when Australian medical researcher Struan Sutherland claimed the White-tailed Spider as the culprit of severe skin ulcers and necrotic lesions. This was perpetuated by a number of articles in medical journals. Research by toxicologist Geoff Isbister and arachnologist Mike Gray investigated verified Lampona cylindrata bites, patients complained about pain, redness and itchiness, but researchers could find no resulting necrotic ulcers or other confirmed infections.
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Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators (cytokines, interleukins, leukotrienes, and prostaglandins) from their granules into the surrounding tissue causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation, and smooth muscle contraction. This results in rhinorrhea, itchiness, dyspnea, and anaphylaxis. Depending on the individual, allergen, and mode of introduction, the symptoms can be system-wide (classical anaphylaxis), or localized to particular body systems; asthma is localized to the respiratory system and eczema is localized to the dermis.
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The most commonly reported side effects of tapentadol therapy in clinical trials were nausea, vomiting, dizziness, sleepiness, itchiness, dry mouth, headache, and fatigue. According to the World Health Organization there is little evidence to judge the abuse potential of tapentadol. Although early pre-clinical animal trials suggested that tapentadol has a reduced abuse liability compared to other opioid analgesics the US DEA placed tapentadol into Schedule II, the same category as stronger opioids more commonly used recreationally, such as morphine, oxycodone, and fentanyl. Tapentadol has been demonstrated to reduce the seizure threshold in patients.
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A 2007 assessment of harm from recreational drug use (mean physical harm and mean dependence liability). Buprenorphine was ranked 9th in dependence, 8th in physical harm, and 11th in social harm. Common adverse drug reactions associated with the use of buprenorphine are similar to those of other opioids and include: nausea and vomiting, drowsiness, dizziness, headache, memory loss, cognitive and neural inhibition, perspiration, itchiness, dry mouth, shrinking of the pupils of the eyes (miosis), orthostatic hypotension, male ejaculatory difficulty, decreased libido, and urinary retention. Constipation and CNS effects are seen less frequently than with morphine.
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Excessive earwax may impede the passage of sound in the ear canal, causing mild conductive hearing loss, pain in the ear, itchiness, or dizziness. Untreated impacted wax can result in hearing loss, social withdrawal, poor work function and even mild paranoia. Some people with impacted wax present with perforated eardrums, the reason for this is usually self-induced as compacted earwax alone cannot perforate the eardrum, for example due to the use of earbuds. Physical exam usually checks for visibility of the tympanic membrane which can be blocked by excessive cerumen.
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Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form) for patients unresponsive to less potent corticosteroids, and penile phimosis. In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone. Some low-quality evidence suggests the use of mometasone for symptomatic improvement in children with adenoid hypertrophy. Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis.
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Side effects can include blood from mouth, skin rashes, dizziness, sedation, shortness of breath, hypersensitivity reaction, fainting (syncope or near syncope), nausea or vomiting, confusion, loss of short-term memory, drowsiness, changes in blood, allergic reactions, euphoria, dysphoria, abdominal pain, itchiness, easy bruising, bleeding gums, vivid dreams, dry mouth and addiction. Genetic differences between people give rise to differing rates of metabolism of codeine to morphine. In about 5% of people this may happen particularly fast, leading to higher levels of morphine being passed through breast milk in amounts potentially able to cause fatal respiratory depression of a breastfed baby.
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MSCs have also been shown to travel to sites of inflammation far from the injection site. MSCs can be easily extracted through well-established procedures such as bone marrow aspiration. Also, transplanted MSCs pose little risk for rejection as they are derived from the patients own tissue, so are genetically identical, however graft versus host disease is a possibility, where the cells change enough while outside the patient's body that the immune system recognizes them as foreign and can attempt to reject them. This can lead to symptoms such as itchiness, sensitive/raw skin and shedding or dry skin. .
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Side effects observed in fluoxetine-treated persons in clinical trials with an incidence >5% and at least twice as common in fluoxetine-treated persons compared to those who received a placebo pill include abnormal dreams, abnormal ejaculation, anorexia, anxiety, asthenia, diarrhea, dry mouth, dyspepsia, flu syndrome, impotence, insomnia, decreased libido, nausea, nervousness, pharyngitis, rash, sinusitis, somnolence, sweating, tremor, vasodilation, and yawning. Fluoxetine is considered the most stimulating of the SSRIs (that is, it is most prone to causing insomnia and agitation). It also appears to be the most prone of the SSRIs for producing dermatologic reactions (e.g. urticaria (hives), rash, itchiness, etc.).
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The pathogenicity of M. ozzardi needs further research. Although the adult worms live in the body cavities and the mesentery, they seem to cause little or no harm to their human hosts. As a result, infected people rarely present any symptoms. However, a few clinical manifestations have been reported: # Moderate fever # Coldness in the legs # Joint pains, like articular pain or arthralgias # Headaches # Pruritus (itchiness) # Skin eruptions # Pulmonary symptoms # Lymphadenitis - inflammation of the lymph nodes # Adenopathy - enlargement of the lymph nodes # Hepatomegaly - enlargement of the liver M. ozzardi is also considered as a possible cause for corneal lesions.
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The combination severely suppresses bone marrow function, resulting in fewer red blood cells, white blood cells, and platelets, so many people taking it are at risk for infections, anemia, and blood loss from lack of clotting. It also causes digestive problems, with more than 10% of people experiencing loss of appetite, diarrhea, nausea, and vomiting. More than 10% of people experience fatigue and fever. Between 1 and 10% of people have skin and mucosa issues, like rashes and itchiness, or mouth sores, as well as skin sloughing, numbness, redness, and swelling of their palms and soles.
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Infestation of N. cati causes several symptoms such as severe itchiness, alopecia, scales and characteristic dry, crusted, pruritic lesions that first appear in the region of the ears and rapidly spreads over the face, eyelids, neck and continues to infest the whole body. Clinical symptoms appear within the incubation period, which is most commonly 10 days to 8 weeks after transmission has happened from contact with an infested animal. Skin will become thickened and colour of crusting will change yellowish or grey as the parasitic disease progresses. Self-trauma because of severe itching can cause excoriations to develop severe dermatitis, secondary bacterial infections.
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Its most common side effects are digestive (mostly dyspepsia, mouth swelling, nausea, vomiting and taste disturbance), vasomotor (mostly flushing, fainting, dizziness, sweating, weakness, palpitations, shortness of breath and blurred vision) or dermatologic (usually itchiness, rash, local irritation near to the injection site and hair loss) in nature, although conjunctivitis, blood dyscrasias, kidney damage, joint pain, muscle aches/pains and liver dysfunction are also common. Less commonly, it can cause GI bleeds, dry mucous membranes and gingivitis. Rarely it can cause: aplastic anaemia, ulcerative enterocolitis, difficulty swallowing, angiooedema, pneumonitis, pulmonary fibrosis, hepatotoxicity, cholestatic jaundice, peripheral neuropathy, Guillain–Barré syndrome, encephalopathy, encephalitis and photosensitivity.
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Additionally, there had not been a case of arachnogenic necrosis reported in the two hundred years of European colonisation before these cases. Of the 130 cases of white tail spider bites studied by Isbister and Gray, more than 60% reported that the person had been bitten by spiders that had got into clothing, towels or beds. Clinical toxicologist Geoffrey Isbister studied 130 cases of arachnologist-identified white-tailed spider bites, and found no necrosis or confirmed infections, concluding that such outcomes are very unlikely for a white-tailed spider bite. The major effects from a bite in this study were local (pain, a red mark, local swelling and itchiness); and rarely systemic (nausea, vomiting, malaise or headache).
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Other problems that can contribute to anal itching include pinworms, hemorrhoids, tears of the anal skin near the mucocutaneous junction (fissures), and skin tags (abnormal local growth of anal skin). Aside from diseases relative to the condition, a common view suggests that the initial cause of the itch may have passed, and that the illness is in fact prolonged by what is known as an itch-scratch-itch cycle. It states that scratching the itch encourages the release of inflammatory chemicals, which worsen redness, intensifies itchiness and increases the area covered by dry skin, thereby causing a snowball effect. Some authorities describe “psychogenic pruritus” or "functional itch disorder", where psychological factors may contribute to awareness of itching.
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Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen. It is a result of an overgrowth of granulation tissue (collagen type 3) at the site of a healed skin injury which is then slowly replaced by collagen type 1. Keloids are firm, rubbery lesions or shiny, fibrous nodules, and can vary from pink to the color of the person's skin or red to dark brown in color. A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, and changes in texture.
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Doxepin is used as a pill to treat major depressive disorder, anxiety disorders, and chronic hives, and for short-term help with trouble remaining asleep after going to bed (a form of insomnia). As a cream it is used for short-term treatment of itchiness to due atopic dermatitis or lichen simplex chronicus. In 2016 the American College of Physicians advised that insomnia be treated first by treating comorbid conditions, then with cognitive behavioral therapy and behavioral changes, and then with drugs; doxepin was among those recommended for short-term help maintaining sleep, on the basis of weak evidence. The 2017 American Academy of Sleep Medicine recommendations focused on treatment with drugs were similar.
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In the early stages of acute allergic reaction, lymphocytes previously sensitized to a specific protein or protein fraction react by quickly producing a particular type of antibody known as secreted IgE (sIgE), which circulates in the blood and binds to IgE-specific receptors on the surface of other kinds of immune cells called mast cells and basophils. Both of these are involved in the acute inflammatory response. Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators (cytokines, interleukins, leukotrienes, and prostaglandins) into the surrounding tissue causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation, and smooth muscle contraction. This results in runny nose, itchiness, shortness of breath, and potentially anaphylaxis.
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The color change was officially reported as being caused by a lack of chemicals used for the water treatment process, which resulted in the pH level of the pool to change. The diving pool was closed on 12 August after it began producing a sulfuric smell and was suggested to be a cause of eye itchiness among some athletes who competed within it. A report said that a sanitation contractor had added the dechlorinating sterilizer hydrogen peroxide to water that was already chlorinated, neutralizing the sterilizing effect of chlorine. An overhead camera crashed at the Olympic Park on 15 August On 15 August, seven people, including an 11-year-old girl, were injured after an overhead TV camera crashed to the ground at the Olympic Park.
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The production of conjugated estrogens sold under the name Premarin (with pregnant mare urine as the primary ingredient) is widely criticized (including by PETA and the Animal Liberation Front) as abusive. About 100,000 pregnant mares are kept locked in stalls in Canada and in China; the foals are killed shortly after birth so that the mare can again be impregnated.. These mares are kept in a permanent state of thirst so produce a more concentrated during, and live with a probe that causes itchiness. According to some accounts, they are frequent beaten and sometimes miscarry due to their living conditions. Despite multiple petitions to the lab, the production of Premarin will likely continue under the same conditions as the market is growing.
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Side effects of ciclosporin can include gum enlargement, increased hair growth, convulsions, peptic ulcers, pancreatitis, fever, vomiting, diarrhea, confusion, increased cholesterol, trouble breathing, numbness and tingling (particularly of the lips), itchiness, high blood pressure, potassium retention (possibly leading to hyperkalemia), kidney and liver dysfunction, burning sensations at finger tips, and an increased vulnerability to opportunistic fungal and viral infections. Ciclosporin causes hypertension by inducing vasoconstriction in the kidneys and increasing sodium reabsorption. The increase in blood pressure can cause cardiovascular events; it is thus recommended that the lowest effective dose for people requiring long-term treatment be used. Ciclosporin use after a kidney transplantation is associated with increased levels of uric acid in the blood and, in some cases, gout.
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Quinine can cause unpredictable serious and life-threatening blood and cardiovascular reactions including low platelet count and hemolytic-uremic syndrome/thrombotic thrombocytopenic purpura (HUS/TTP), long QT syndrome and other serious cardiac arrhythmias including torsades de pointes, blackwater fever, disseminated intravascular coagulation, leukopenia, and neutropenia. Some people who have developed TTP due to quinine have gone on to develop kidney failure. It can also cause serious hypersensitivity reactions include anaphylactic shock, urticaria, serious skin rashes, including Stevens–Johnson syndrome and toxic epidermal necrolysis, angioedema, facial edema, bronchospasm, granulomatous hepatitis, and itchiness. The most common adverse effects involve a group of symptoms called cinchonism, which can include headache, vasodilation and sweating, nausea, tinnitus, hearing impairment, vertigo or dizziness, blurred vision, and disturbance in color perception.
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The most common adverse reactions encountered in Phase II and Phase III trials were nausea (5.5%), headache (4.7%), and diarrhea (4.4%), as well as rash (2.7%) and itchiness (2.1%). Other less frequent but serious adverse reactions included hematologic disorders, hepatotoxicity, Clostridium difficile colitis, bronchospasm, infusion-related reactions including Red Man Syndrome, and anaphylactic shock. In trials, dalbavancin was associated with higher rates of hemorrhagic events compared to comparator groups and should be a precaution in patients undergoing surgery or taking anticoagulants. Patients on dalbavancin also had post-baseline alanine aminotransferase (ALT) levels that were 3 times the upper normal limit, some even having elevations 10 times the upper normal limit; however, eight of the twelve dalbavancin-treated patients had comorbid conditions that could affect their ALT, compared to only one patient in the comparator group.
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Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators called (cytokines, interleukins, leukotrienes, and prostaglandins) into the surrounding tissue causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation, and smooth-muscle contraction. This results in runny nose, itchiness, shortness of breath, and potentially anaphylaxis. Depending on the individual, the allergen, and the mode of introduction, the symptoms can be system-wide (classical anaphylaxis), or localized to particular body systems; asthma is localized to the respiratory system while eczema is localized to the skin. After the chemical mediators of the acute response subside, late-phase responses can often occur due to the migration of other white blood cells such as neutrophils, lymphocytes, eosinophils, and macrophages to the initial reaction sites.
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The incidence of these eruptions increases in patients who are currently on, or recently discontinued a valproate-type anticonvulsant drug, as these medications interact in such a way that the clearance of both is decreased and the effective dose of lamotrigine is increased. Side effects such as rash, fever, and fatigue are very serious, as they may indicate incipient SJS, TEN, DRESS syndrome, or aseptic meningitis. Other side effects include loss of balance or coordination, double vision, crossed eyes, pupil constriction, blurred vision, dizziness and lack of coordination, drowsiness, insomnia, anxiety, vivid dreams or nightmares, dry mouth, mouth ulcers, memory problems, mood changes, itchiness, runny nose, cough, nausea, indigestion, abdominal pain, weight loss, missed or painful menstrual periods, and vaginitis. The side-effects profile varies for different patient populations.
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Sir George Clark), Oxford, at the Clarendon Press, 1965, reprinted (with corrections) 1966 "Scots" is the modern preferred usage in all levels of society in Scotland, but occasional use of "Scotch" in varieties of the Scots language continues with terms such as Scotch and English (a game), Scotch fiddle (itchiness), Scotch mile and ell (measures) and many other examples (see the Scots Dialect Dictionary compiled by Alexander Warrack M.A. (1911) republished by Waverley Books 2000). There are other good indicators that the use of "Scotch" has been "whitewashed out" and become a shibboleth. Early versions of dictionaries produced in Burns' wake in the 19th century had titles such as "A Dictionary of the Scotch Dialect of the Lowlands" and modern place names now written as "Scots" e.g., Scotstarvit and Scotscalder existed in previous incarnations as "Scotch".
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The dose-limiting side effects are liver damage, lung disease and immunosuppression. The most common side effects (occurring in >1% of those treated with it) are, in approximately descending order of frequency: diarrhea, respiratory tract infections, hair loss, high blood pressure, rash, nausea, bronchitis, headache, abdominal pain, abnormal liver function tests, back pain, indigestion, urinary tract infection, dizziness, infection, joint disorder, itchiness, weight loss, loss of appetite, cough, gastroenteritis, pharyngitis, stomatitis, tenosynovitis, vomiting, weakness, allergic reaction, chest pain, dry skin, eczema, paraesthesia, pneumonia, rhinitis, synovitis, cholelithiasis and shortness of breath. Whereas uncommon side effects (occurring in 0.1-1% of those treated with the drug) include: constipation, oral thrush, stomatitis, taste disturbance, thrombocytopenia and hives. Rarely (in 0.1% of those treated with it) it can cause: anaphylaxis, angiooedema, anaemia, agranulocytosis, eosinophilia, leucopenia, pancytopenia, vasculitis, toxic epidermal necrolysis, Stevens–Johnson syndrome, cutaneous lupus erythematosus, severe infection, interstitial lung disease, cirrhosis and liver failure.
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In clinical trials of the three-agent combination therapy in metastatic breast cancer, adverse effects occurring in more than half the people taking it included diarrhea, hair loss, and loss of neutrophils; more than 10% of people experienced loss of neutrophils with fever, and loss of leukocytes. After docetaxel was dropped in some people, the most common adverse effects were diarrhea (28.1%), upper respiratory tract infection (18.3%), rash (18.3%), headache (17.0%), fatigue (13.4%), swelling of nasal passages and throat (often due to catching the common cold) (17.0%), weakness (13.4%), itchiness (13.7%), joint pain (11.4%), nausea (12.7%), pain in an extremity (13.4%), back pain (12.1%) and cough (12.1%). In clinical trials of the neoadjuvant use of the combination, more than 50% of people had hair loss and loss of neutrophils. In both uses, more than 10% of people additionally experienced: loss of red blood cells, hypersensitivity or allergic reaction, infusion reactions, decreased appetite, insomnia, distortions in the sense of taste, inflammation of the mouth or lips, constipation, rashes, nail disease, and muscle pain.
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