Sentences Generator
And
Your saved sentences

No sentences have been saved yet

185 Sentences With "ischemic heart disease"

How to use ischemic heart disease in a sentence? Find typical usage patterns (collocations)/phrases/context for "ischemic heart disease" and check conjugation/comparative form for "ischemic heart disease". Mastering all the usages of "ischemic heart disease" from sentence examples published by news publications.

type: All Declarative Interrogative Exclamative

structure: All Simple Compound Complex Compound-Complex

length: All <=10 words 10-20 words 20-30 words 30-50 words

During 15 years of follow up, 580 nurses developed ischemic heart disease.
The most common was hypertension, followed by ischemic heart disease and diabetes mellitus.
The most common was hypertension, followed by ischemic heart disease and diabetes mellitus.
Ischemic heart disease, also known as coronary artery disease, is the most common type of heart disease.
Ischemic heart disease, the second-largest source of expenses, cost a total of $88 billion that year.
Ischemic heart disease is the most common type of heart disease and is caused by narrowed heart arteries.
He is diabetic and suffers from ischemic heart disease and hypothyroidism, and has had treatment for skin cancers.
Millions of Americans have what's known as ischemic heart disease, one of the two conditions examined in the study.
Entidhar lives alone in the northern Jordanian district of Sweilih, and suffers from diabetes, hypertension and ischemic heart disease.
"Someone with uncontrolled hypertension may be at higher risk for ischemic heart disease due to physical activity," Matura added by email.
The men had either ischemic heart disease - meaning blocked or narrowed arteries - or a heart rhythm disorder that required an implanted defibrillator.
"We too found some protective effects for Type 2 diabetes and ischemic heart disease at low levels of alcohol consumption," she said.
For some cardiovascular issues such as ischemic heart disease, erectile dysfunction is a problem in up to 80 percent of men, she said.
Ischemic heart disease -- a condition that restricts blood flow throughout the body -- caused 9.48 million deaths in 20163, an increase of 19% since 2006.
Among people with cardiovascular disease, most had ischemic heart disease, also called coronary heart disease, in which the arteries supplying the heart become narrowed.
The survey shows that diabetes-related costs have grown 36-times faster than those for ischemic heart disease, which kills more people than any other condition.
By 2011, sodium intake had dropped by 15 percent, according to researchers in Britain, average blood pressure declined, and deaths from ischemic heart disease and stroke fell.
Coronary artery disease, also known as ischemic heart disease or coronary heart disease, is the leading cause of death in both men and women in the United States.
Also known as ischemic heart disease is a narrowing of the coronary arteries due to plaque buildup, and the most common type of heart disease in the United States.
Between 1990 and 2016, ischemic heart disease was the top cause of years of life lost in the US, and lung cancer ranked second, without budging, the study showed.
Coronary artery disease, also known as ischemic heart disease or coronary heart disease, is when arteries are clogged with cholesterol, which increases the risk of heart attack and heart failure.
Since 1990, deaths in Mexico from causes like measles, diarrhea, and infant deaths have been dropping, while diet-related diseases like diabetes, ischemic heart disease, and stroke have rapidly increased.
Finally, egg eaters also enjoyed a 12% reduced risk of ischemic heart disease, which is diagnosed in those who show the early signs of gridlocked blood flow to the brain.
The study sample was made up of 36,624 men and 42,970 women aged 45 to 75 who had no history of cancer, stroke, ischemic heart disease, or chronic liver disease.
Each of these 85033,300 children are now set up for higher rates of depression, suicide, substance abuse, health risk behaviors, ischemic heart disease, cancer, chronic lung disease, skeletal fractures, and liver disease.
PCI is commonly performed for ischemic heart disease, or heart problems caused by narrowed arteries, and for so-called acute coronary syndrome, which is typically caused by clots or plaque in the arteries.
These health effects, according to guidelines published by the W.H.O.'s European regional office last year, include tinnitus, sleep disturbance, ischemic heart disease, obesity, diabetes, adverse birth outcomes, and cognitive impairment in children.
The conditions examined — breast and lung cancer, cerebrovascular disease, chronic obstructive pulmonary disease, diabetes, H.I.V./AIDS and ischemic heart disease — are collectively responsible for most of the mortality and serious disease in the population.
But research to date hasn't conclusively linked an early delivery to an increased risk of so-called ischemic heart disease, which happens with the arteries narrow and limit how much blood and oxygen reach the heart.
According to the World Health Organization, ischemic heart disease and stroke are the world's biggest killers, but they can often be prevented if they are identified early in life and properly managed through lifestyle changes and medication.
For example, individuals who had experienced four or more categories of childhood trauma had significantly increased health risks for alcoholism, drug abuse, depression, severe obesity, ischemic heart disease, cancer, chronic lung disease, skeletal fractures, and liver disease. Seriously.
There are three main types of ischemic heart disease: Obstructive coronary artery disease is the result of plaque build-up that causes the heart's large arteries to gradually narrow, reducing and eventually blocking the supply of blood flow to the heart.
Procedures in the "cath lab" – named for the catheters threaded into the heart - are done for all forms of cardiac disease, like congenital heart defects, ischemic heart disease or heart arrhythmias, said lead author Maria Grazia Andreassi of the CNR Institute of Clinical Physiology in Pisa, Italy.
According to the World Health Organization, the health effects of even short-term exposure include sleep disturbance, stress and anxiety, while long-term impacts include increased risk of ischemic heart disease, cognitive impairment among children, stress-related mental health risks and tinnitus (chronic ringing in the ears).
Yet in nine categories, the US scored in the 19903s, including neonatal disorders (21990), non-melanoma skin cancer (21.1), diabetes (24.0), Hodgkin's lymphoma (67), hypertensive heart disease (64), ischemic heart disease (62), chronic kidney disease (62), lower respiratory infections (60), and the adverse effects of medical treatment itself (68).
"Considering our observation that atrial fibrillation is associated with an increased risk of heart failure, sudden cardiac death, and chronic kidney disease (in addition to ischemic heart disease), it seems likely that atrial fibrillation could be acting as a marker for shared underlying risk factors for cardiovascular disease," he said.
In just 20 years, ischemic heart disease and cerebrovascular disease — two types of cardiovascular disease that affect the heart and brain, respectively — leaped from the fourth and fifth leading cause of premature mortality to the first and second, respectively, bumping lower respiratory infections and neonatal preterm birth complications from the top killers globally.
" Holgate, who was not involved in the new research, added that the sample sizes were small but that "the study deliberately selected COPD and ischemic heart disease at-risk patients, and ... overall, the findings add to evidence of the importance of pollutant effects in vulnerable groups and have implications for pollution in general from vehicles (diesel, petrol, brakes and tires) as sources of pollutants.
Mitral regurgitation may also occur as a result of ischemic heart disease (coronary artery disease) or non-ischemic heart disease (dilated cardiomyopathy).
These results suggest that miR27b might be useful for treating patients with ischemic heart disease.
He died in 1984 at Beilinson Hospital in Petah Tikva due to complications from ischemic heart disease.
Coronary artery disease (CAD) occurs when fatty substances adhere to the walls of coronary arteries supplying the heart, narrowing them and constricting blood flow, a process known as atherosclerosis, the most common cause of coronary ischemia.["Ischemia." Ischemic Heart Disease. Ischemic Heart Disease, n.d. Web. 6 Nov. 2010.
In October 2019, a group at Okayama University developed a model of ischemic heart disease using cardiomyocytes differentiated from iPS cells.
Ischemic heart disease, pneumonia and mental health were the top three reasons for inpatient separation, all higher rates than the Alberta average.
Ischemic heart disease is the leading cause of morbidity and mortality in Western countries, and its incidence has increased drastically in the relatively short span of a few decades. Due to the blockage of the coronary arteries, blood supply to the heart is cut off which leads to inadequate supply of blood to the heart muscle resulting in ischemic heart disease.
Whereas, there is remarkable increment in the number of other diseases like Ischemic heart disease (IHD), Chronic obstructive pulmonary disease (COPD), Road injuries, Stroke and Diabetes.
By 2013, the leading causes of death were non-communicable diseases (predominantly stroke and ischemic heart disease). The leading health risk factor in Tajikistan is dietary risks.
In the long-term, flecainide seems to be safe in people with a healthy heart with no signs of left ventricular hypertrophy, ischemic heart disease, or heart failure.
Taking vitamin D supplements does not meaningfully reduce the risk of stroke, cerebrovascular disease, cardial infarction, or ischemic heart disease. Supplementation may have no effect on blood pressure.
Attilio Maseri (born November 12, 1935) is an Italian cardiologist. Maseri is considered a leading researcher in the field of ischemic heart disease. His patients have included Queen Elizabeth II and Pope John Paul II.
It is hypothesized that the Danish government's efforts to decrease trans fat intake from 6 g to 1 g per day over 20 years is related to a 50% decrease in deaths from ischemic heart disease.
Goldbourt et al., “Factors Predictive of Long-Term Coronary Heart Disease Mortality Among 10,059 Male Israeli Civil Servants and Municipal Employees: A 23-Year Mortality Follow-up to the Israeli Ischemic Heart Disease Study.” Cardiology 82 (1993), 100-121.
Darolutamide was also associated with higher incidences of ischemic heart disease (4.0% vs. 3.4% for placebo) and heart failure (2.1% vs. 0.9% for placebo). In terms of laboratory test abnormalities, darolutamide was associated with decreased neutrophil count (20% vs.
The role of stress and the sympathetic nervous system in hypertension and ischemic heart disease: advantages of therapy with beta-receptor blockers. Clinical and Experimental Hypertension. Part A, Theory and Practice, 7(7), 907–932. particularly ambulatory blood pressure.
The nitrate esters isosorbide dinitrate (Isordil) and isosorbide mononitrate (Imdur, Ismo, Monoket, Mononitron) are converted in the body to nitric oxide, a potent natural vasodilator. In medicine, these esters are used as a medicine for angina pectoris (ischemic heart disease).
Most notably, SOD2 is pivotal in reactive oxygen species (ROS) release during oxidative stress by ischemia-reperfusion injury, specifically in the myocardium as part of a heart attack (also known as ischemic heart disease). Ischemic heart disease, which results from an occlusion of one of the major coronary arteries, is currently still the leading cause of morbidity and mortality in western society. During ischemia reperfusion, ROS release substantially contribute to the cell damage and death via a direct effect on the cell as well as via apoptotic signals. SOD2 is known to have a capacity to limit the detrimental effects of ROS.
Most notably, SOD1 is pivotal in reactive oxygen species (ROS) release during oxidative stress by ischemia-reperfusion injury, specifically in the myocardium as part of a heart attack (also known as ischemic heart disease). Ischemic heart disease, which results from an occlusion of one of the major coronary arteries, is currently still the leading cause of morbidity and mortality in western society. During ischemia reperfusion, ROS release substantially contribute to the cell damage and death via a direct effect on the cell as well as via apoptotic signals. SOD1 is known to have a capacity to limit the detrimental effects of ROS.
Some Turkmen > opposition sources also claim that Niyazov died several days before the > officially announced date of 21 December. Foreign news reports also claimed > that Niyazov also suffered from ischemic heart disease and kidney failure > due to being overweight and overindulgence of alcohol.
Noncommunicable diseases (NCDs) are prime causes of deaths in pacific islands, responsible for 60% deaths in Solomon Islands. Premature mortality from NCDs was 1900 in 2016. Ischemic heart disease, stroke and diabetes were the main causes of mortality due to NCDs in 2017.
Hypokalemia is an important cause of acquired long QT syndrome, and may predispose the patient to torsades de pointes. Digitalis use may increase the risk that hypokalemia will produce life-threatening arrhythmias. Hypokalemia is especially dangerous in patients with ischemic heart disease.
According to one review published in 2003, reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease.
Single photon emission computed tomography (SPECT), a nuclear medicine imaging methodology using gamma rays emitted by a radioactive tracer injected into the blood stream, which ultimately distributes into the heart. SPECT is most commonly used for myocardial perfusion imaging to detect ischemic heart disease.
Common causes are Normal variant, Right ventricular hypertrophy or strain, Congenital heart disease such as atrial septal defect and Ischemic heart disease. In addition, a right bundle branch block may also result from Brugada syndrome, pulmonary embolism, rheumatic heart disease, myocarditis, cardiomyopathy, or hypertension.
MiR-27b also targets Thrombospondin-1, an antiangiogenic protein. Reduction in miR-27b increases Thrombospondin-1 levels, which decreases angiogenesis by silencing Drosha and Dicer. Thus, miR-27b can be used to promote angiogenesis in patients with ischemic heart disease by suppressing Thrombospondin-1.
Interruptions of coronary circulation quickly cause heart attacks (myocardial infarctions), in which the heart muscle is damaged by oxygen starvation. Such interruptions are usually caused by ischemic heart disease (coronary artery disease) and sometimes by embolism from other causes like obstruction in blood flow through vessels.
Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status. Pharmacogenetics. 13(10):627-32, (2003).Killalea, S.M. and Krum, H., Systematic Review of the Efficacy and Safety of Perhexiline in the Treatment of Ischemic Heart Disease. American Journal of Cardiovascular Drugs. 1(3):193-204. (2001).
Globally, disability adjusted life years (DALYs) lost to ischemic heart disease are predicted to account for 5.5% of total DALYs in 2030, making it the second-most-important cause of disability (after unipolar depressive disorder), as well as the leading cause of death by this date.
Cardiovascular disease is the leading cause of death in the world. Ischemic heart disease develops when stenosis and occlusion of coronary arteries develops, leading to reduced perfusion of the cardiac tissues. There is ongoing research exploring techniques that might be able to induce healthy neovascularization of ischemic cardiac tissues.
In patients with ischemic heart disease there is an accumulation of angiogenic growth factors in the pericardial fluid. These contribute to angiogenesis (the formation of new blood vessels) and arteriogenesis (the increase in diameter of existing arterioles). This helps to prevent myocardial ischemia (lack of oxygen to the heart).
In the Hidalgo et al. (2009) study, disease progression was found to be different across genders and ethnicities. For example, hypertension, diabetes, and renal disorders tend to be more comorbid in black males, while ischemic heart disease, infarctions, pulmonary complications and hypercholesterolemia are more comorbid in white males.
Zolmitriptan should not be given to patients with ischemic heart disease (angina pectoris, history of myocardial infarction, or documented silent ischemia) or to patients who have symptoms or findings consistent with ischemic heart disease, coronary artery vasospasm, including Prinzmetal's angina, or other significant underlying cardiovascular disease. Zolmitriptan may increase blood pressure, it should not be given to patients with uncontrolled hypertension, should not be used within 24 hours of treatment with another 5-HT1 agonist, or an ergotamine-containing or ergot-type medication like dihydroergotamine or methysergide, and should not be administered to patients with hemiplegic or basilar migraine. Concurrent administration of MAOI or use of zolmitriptan within 2 weeks of discontinuation of MAO-A inhibitor therapy is contraindicated.
Use is not recommended in those with structural heart disease or ischemic heart disease. Flecainide is a class Ic antiarrhythmic agent. It works by decreasing the entry of sodium in heart cells, causing prolongation of the cardiac action potential. Flecainide was approved for medical use in the United States in 1985.
POMDPs can be used to model many kinds of real- world problems. Notable applications include the use of a POMDP in management of patients with ischemic heart disease, assistive technology for persons with dementia, the conservation of the critically endangered and difficult to detect Sumatran tigers and aircraft collision avoidance.
An electrocardiogram (ECG/EKG) may be used to identify arrhythmias, ischemic heart disease, right and left ventricular hypertrophy, and presence of conduction delay or abnormalities (e.g. left bundle branch block). Although these findings are not specific to the diagnosis of heart failure, a normal ECG virtually excludes left ventricular systolic dysfunction.
Studies, including the Women's Ischemia Syndrome Evaluation (WISE), suggest that microvascular angina is part of the pathophysiology of ischemic heart disease, perhaps explaining the higher rates of angina in women than in men, as well as their predilection towards ischemia and acute coronary syndromes in the absence of obstructive coronary artery disease.
Sachar was suffering from ischemic heart disease and had an artificial cardiac pacemaker implanted. In April 2018, he was admitted to the Fortis Hospital in New Delhi, following complaint of recurrent vomiting. During the course of his treatment he contracted pneumonia and died on 20 April, Friday midnight. He was 94 years old.
Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used for the diagnosis of ischemic heart disease. The underlying principle is that under conditions of stress, diseased myocardium receives less blood flow than normal myocardium. MPI is one of several types of cardiac stress test. A cardiac specific radiopharmaceutical is administered. E.g.
During the hearings, it came to light that Sudha has developed Ischemic Heart Disease. Both the Sessions and the Hon’ble High Court rejected the bail applications. The Hon’ble Supreme Court dismissed the petition as withdrawn after asking the lawyer why Sudha needs to seek bail on medical grounds when she has “such a good case on merits'.
In 1995, Arato directed The Girl of the Silence, which stars Mami Nakamura and Kaori Momoi. He returned with the 2003 film, Akame 48 Waterfalls, starring Takijirō Ōnishi, Michiyo Okusu and Shinobu Terajima. His 2010 film, The Fallen Angel, starred Toma Ikuta. He died of ischemic heart disease on 7 November 2016 at the age of 70.
A 28-year follow-up of 740 World War II veterans whose spleens were removed on the battlefield showed a significant increase in the usual death rate from pneumonia (6 rather than the expected 1.3) and an increase in the death rate from ischemic heart disease (41 rather than the expected 30), but not from other conditions.
For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should not be initiated at the full replacement dose. Since thyroid hormone increases the heart's oxygen demand by increasing heart rate and contractility, starting at higher doses may cause an acute coronary syndrome or an abnormal heart rhythm.
In addition, the Tobacco Institute responded to Hirayama's 1981 study by writing a letter to his superior criticizing the study. In 1984, Hirayama published a cohort study of 265,118 adults which reached conclusions similar to those of his 1981 study, namely, that non-smoking wives of smoking husbands were at an increased risk of lung cancer and ischemic heart disease.
Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation.
There is also an increased risk for cardiovascular complications, including hypertension and ischemic heart disease, and kidney disease. Other risks include stroke and venous thromboembolism. It seems pre-eclampsia does not increase the risk of cancer. Lowered blood supply to the fetus in pre-eclampsia causes lowered nutrient supply, which could result in intrauterine growth restriction (IUGR) and low birth weight.
Remnant cholesterol is especially predictive of coronary artery disease in patients with normal total cholesterol. High plasma remnant cholesterol is associated with increased plasma triglyceride levels. Hypertriglyceridemia is characteristic of high plasma remnant cholesterol, but persons with high plasma triglycerides without high remnant cholesterol rarely have coronary artery disease. Remnant cholesterol has about twice the association with ischemic heart disease as LDL cholesterol.
It is also used in the treatment of familial Mediterranean fever, in which it reduces attacks and the long-term risk of amyloidosis. Colchicine is effective for prevention of atrial fibrillation after cardiac surgery. Potential applications for colchicine's anti-inflammatory effects have been studied with regard to atherosclerosis, acute coronary syndromes, and chronic coronary disease (e.g., stable coronary artery disease/ischemic heart disease).
Aircraft engines are the major source of noise and can exceed 140 decibels (dB) during takeoff. While airborne, the main sources of noise are the engines and the high speed turbulence over the fuselage. There are health consequences of elevated sound levels. Elevated workplace or other noise can cause hearing impairment, hypertension, ischemic heart disease, annoyance, sleep disturbance, and decreased school performance.
Before the redesign, however, in 1936, Starr had secured records on multiple healthy people, namely medical students, faculty, friends, and family members. Over the next 40 years, he would study his subjects and eventually report a clinical series on them, detailing such observations as, "Patients with clinical evidence of ischemic heart disease who also had abnormal BCGs developed twice as many recurrences as did those having ischemic heart disease and normal records." During World War II, Isaac Starr and Dr. Eugene A. Stead were members of a committee of the National Research Council that was tasked with deciding which chemicals and medications were considered important to medicine. Stead noted in a memoir he felt indebted to Starr for taking him to the National Gallery of Art during some free hours after a day of work which lead to his appreciation of art.
It also should not be used in people with severe low blood pressure or reduced systemic vascular resistance. It should be used in caution in people with ischemic heart disease especially following heart attack or a recent episode of angina due to the risk of tachycardia. It should not be used in people with reduced blood volume. Safety in pregnant women has not been established.
Cardiac ischemia may be asymptomatic or may cause chest pain, known as angina pectoris. It occurs when the heart muscle, or myocardium, receives insufficient blood flow. This most frequently results from atherosclerosis, which is the long-term accumulation of cholesterol-rich plaques in the coronary arteries. Ischemic heart disease is the most common cause of death in most Western countries and a major cause of hospital admissions.
The decision to perform a percutaneous coronary intervention (PCI) is usually based on angiographic results alone. Angiography can be used for the visual evaluation of the inner diameter of a vessel. In ischemic heart disease, deciding which narrowing is the culprit lesion is not always clear-cut. Fractional flow reserve provides a functional evaluation, by measuring the pressure decline caused by a vessel narrowing.
Spielmann became steadily more withdrawn and depressed, and one day in August 1942, he locked himself in his Stockholm apartment and did not emerge for a week. On August 20, neighbors summoned police to check on him. They entered the apartment and found Spielmann dead. The official cause of death was ischemic heart disease, but it has been claimed that he intentionally starved himself.
Cor pulmonale has become less common since the use of supplemental oxygen. COPD often occurs along with a number of other conditions, due in part to shared risk factors. These conditions include ischemic heart disease, high blood pressure, diabetes mellitus, muscle wasting, osteoporosis, lung cancer, anxiety disorder, sexual dysfunction, and depression. In those with severe disease, a feeling of always being tired is common.
The cause of death was cerebral insufficiency and pneumonia due to recent subendocardial infarction. For the last three-and-a-half years of his life, he suffered from ischemic heart disease with episodes of cardiac arrhythmia.Death certificate for Roy Lee Lumpkin, born January 27, 1907, died March 31, 1974. Texas Department of State Health Services; Austin Texas, USA; Texas Death Certificates, 1903–1982. Ancestry.com.
The Disability Adjusted Life Years per percent is dominated by Non-Communicable Diseases, NCDs. Low back and neck pain has the highest share, 8.08% of total DALYs, but it is slightly decreasing. Ischemic heart disease is second largest with 7.42% of total DALYs, COPD is increasing and has 3.09% of total DALYs. Injuries, including violence and self harm, have a smaller share of total DALYs.
The highest incident of sudden cardiac death (SCD) in youth is due to ischemic heart disease. According to a study on SCD between 2000–2006, 79% of youth in the case group had symptoms within 12 months of death. Symptoms included angina and dyspnoea. In 35–40% of unexplained youth deaths, genetic alterations in genes involved in the cardiac action potential is the cause.
Similar results were found in other studies. A 30-year longitudinal study in Denmark of 5,249 employed Caucasian men aged 40–59 years showed that men working 41–45 hours per week had a 59% increased risk of mortality due to ischemic heart disease compared to men working less than 40 hours per week. The authors also found that physical fitness played a significant role, where among men with low physical fitness, those working more than 45 hours per week had more than twice the risk of death by ischemic heart disease compared to men working less than 40 hours per week; while this increased risk was not seen among the fittest men. Furthermore, a study based on data from the Swedish twin registry showed that there was an association between overtime work of more than 5 hours a week and increased mortality in women.
A splenectomy also results in a greatly diminished frequency of memory B cells. A 28-year follow-up of 740 World War II veterans who had their spleens removed on the battlefield showed a significant increase in the usual death from pneumonia (6 deaths rather than the expected 1.74) and an increase in the deaths from ischemic heart disease (41 deaths rather than the expected 30.26) but not from other conditions.
Commonly used hypnotics include thiopental, propofol and etomidate. The neuromuscular blocking agents paralyze all of the skeletal muscles, most notably and importantly in the oropharynx, larynx, and diaphragm. Opioids such as fentanyl may be given to attenuate the responses to the intubation process (accelerated heart rate and increased intracranial pressure). This is supposed to have advantages in patients with ischemic heart disease and those with brain injury (e.g.
HIG1 domain family member 1A (HIGD1A), also known as hypoglycemia/hypoxia inducible mitochondrial protein1-a (HIMP1-a) and hypoxia induced gene 1 (HIG1), is a protein that in humans is encoded by the HIGD1A gene on chromosome 3. This protein promotes mitochondrial homeostasis and survival of cells under stress and is involved in inflammatory and hypoxia-related diseases, including atherosclerosis, ischemic heart disease, and Alzheimer’s disease, as well as cancer.
Treatment for physiologic sinus tachycardia involves treating the underlying causes of the tachycardia response. Beta blockers may be used to decrease tachycardia in patients with certain conditions, such as ischemic heart disease and rate-related angina. In patients with inappropriate sinus tachycardia, careful titration of beta blockers, salt loading, and hydration typically reduce symptoms. Patients who are unresponsive to such treatment can undergo catheter ablation to potentially repair the sinus node.
Deaths due to hypertensive heart disease per million persons in 2012 Disability-adjusted life year for hypertensive heart disease per 100,000 inhabitants in 2004. Hypertension or high blood pressure affects at least 26.4% of the world's population. Hypertensive heart disease is only one of several diseases attributable to high blood pressure. Other diseases caused by high blood pressure include ischemic heart disease, stroke, peripheral arterial disease, aneurysms and kidney disease.
Prophylactic irradiation of the breasts can be used to decrease the incidence and severity of gynecomastia with estrogens. Severe adverse effects of EMP are thromboembolic and cardiovascular complications including pulmonary embolism, deep vein thrombosis, stroke, thrombophlebitis, coronary artery disease (ischemic heart disease; e.g., myocardial infarction), thrombophlebitis, and congestive heart failure with fluid retention. EMP produces cardiovascular toxicity similarly to diethylstilbestrol, but to a lesser extent in comparison at low doses (e.g.
Coronary artery disease, also known as "ischemic heart disease", is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and is one of the causes of sudden cardiac death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn.
In 1975, the Lasker Special Public Health Award was awarded to the team that developed chlorothiazide. The results of these studies prompted public health campaigns to increase public awareness of hypertension and promoted the measurement and treatment of high blood pressure. These measures appear to have contributed at least in part to the observed 50% fall in stroke and ischemic heart disease between 1972 and 1994. Soon more drugs became available to treat hypertension.
For coronary artery disease (ischemic heart disease), coronary artery bypass surgery and percutaneous coronary intervention (coronary balloon angioplasty) are the two primary means of revascularization. When those cannot be done, transmyocardial revascularization or percutaneous myocardial revascularization, done with a laser, may be an option. Treatment for gangrene often requires revascularization, if possible. The surgery is also indicated to treat ischemic wounds (inadequate tissue perfusion) in some forms of chronic wounds, such as diabetic ulcers.
This ECG from the same patient shows atrial fibrillation at around 126 beats per minute. Sick sinus syndrome (SSS), is a group of abnormal heart rhythms (arrhythmias) presumably caused by a malfunction of the sinus node, the heart's primary pacemaker. Tachycardia-bradycardia syndrome is a variant of sick sinus syndrome in which the arrhythmia alternates between slow and fast heart rates. Tachycardia-bradycardia syndrome is often associated with ischemic heart disease and heart valve disease.
The shift towards patient advocacy and interpersonal collaboration allows shared trust, respect, and healthcare goals. Noncommunicable diseases (NCDs) are now the leading cause of death worldwide over communicable diseases. The 5 leading causes of death in the US in 2017 were all non-communicable diseases: ischemic heart disease, Alzheimer's disease, lung cancer, stroke, and chronic obstructive pulmonary disorder. NCDs require prolonged management that usually lasts for the rest of a person's life.
Diagram illustrating the main complications of persistent high blood pressure Hypertension is the most important preventable risk factor for premature death worldwide. It increases the risk of ischemic heart disease, strokes, peripheral vascular disease, and other cardiovascular diseases, including heart failure, aortic aneurysms, diffuse atherosclerosis, chronic kidney disease, atrial fibrillation, and pulmonary embolism. Hypertension is also a risk factor for cognitive impairment and dementia. Other complications include hypertensive retinopathy and hypertensive nephropathy.
Earplugs can be used to protect the user's ears from loud noises. Exposure to noise is associated with several negative health outcomes. Depending on duration and level of exposure, noise may cause or increase the likelihood of hearing loss, high blood pressure, ischemic heart disease, sleep disturbances, injuries, and even decreased school performance. There are also causal relationships between noise and psychological effects such as annoyance, psychiatric disorders, and effects on psychosocial well-being.
Coronary artery disease (CAD), also known as ischemic heart disease, is responsible for 62 to 70 percent of all SCDs. CAD is a much less frequent cause of SCD in people under the age of 40. Cases have shown that the most common finding at postmortem examination of sudden cardiac death (SCD) is chronic high-grade stenosis of at least one segment of a major coronary artery, the arteries that supply the heart muscle with its blood supply.
In addition to the classic risk factors such as smoking, high blood pressure, and diabetes, genetic studies have shown that a common abnormality in the prothrombin gene (G20210A) increases the risk of cardiovascular events in people with FH. Several studies found that a high level of lipoprotein(a) was an additional risk factor for ischemic heart disease. The risk was also found to be higher in people with a specific genotype of the angiotensin-converting enzyme (ACE).
Myocardial infarction is a common presentation of coronary artery disease. The World Health Organization estimated in 2004, that 12.2% of worldwide deaths were from ischemic heart disease; with it being the leading cause of death in high- or middle-income countries and second only to lower respiratory infections in lower-income countries. Worldwide, more than 3 million people have STEMIs and 4 million have NSTEMIs a year. STEMIs occur about twice as often in men as women.
Approximately 80% of deaths linked to non-communicable diseases occur in developing countries. For instance, urbanization and aging have led to increasing poor health conditions related to non-communicable diseases in India. The fastest-growing causes of disease burden over the last 26 years were diabetes (rate increased by 80%) and ischemic heart disease (up 34%). More than 60% of deaths, about 6.1 million, in 2016 were due to NCDs, up from about 38% in 1990.
Dapoxetine should not be used in men with moderate to severe hepatic impairment and in those receiving CYP3A4 inhibitors such as ketoconazole, ritonavir, and telithromycin. Dapoxetine can also not be used in patients with heart failure, permanent pacemaker, or other significant ischemic heart disease. Caution is advised in men receiving thioridazine, monoamine oxidase inhibitors, SSRIs, serotonin-norepinephrine reuptake inhibitors, or tricyclic antidepressant. If a patient stops taking one of these drugs, he should wait for 14 days before taking dapoxetine.
Coronary artery disease (CAD), also known as coronary heart disease (CHD), ischemic heart disease (IHD), or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of plaque (atherosclerosis) in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw.
Dressler syndrome is best treated with high dose aspirin. In some resistant cases, corticosteroids can be used but are not preferred (avoided) in first month due to the high frequency of impaired ventricular healing leading to increased rate of ventricular rupture. Other NSAIDs, though once used to treat Dressler syndrome, are less advocated and should be avoided in patients with ischemic heart disease. One NSAID in particular, indomethacin, can inhibit new collagen deposition, thus impairing the healing process for the infarcted region.
As of 2010, angina due to ischemic heart disease affects approximately 112 million people (1.6% of the population) being slightly more common in men than women (1.7% to 1.5%). In the United States, 10.2 million are estimated to experience angina with approximately 500,000 new cases occurring each year. Angina is more often the presenting symptom of coronary artery disease in women than in men. The prevalence of angina rises with increasing age, with a mean age of onset of 62.3 years.
Sienkiewicz's tomb, St. John's Cathedral, Warsaw Sienkiewicz died on 15 November 1916, at the Grand Hotel du Lac in Vevey, Switzerland, where he was buried on 22 November. The cause of death was ischemic heart disease. His funeral was attended by representatives of both the Central Powers and the Entente, and an address by Pope Benedict XV was read. In 1924, after Poland had regained her independence, Sienkiewicz's remains were repatriated to Warsaw, Poland, and placed in the crypt of St. John's Cathedral.
It has been shown that BNIP3 interacts with the voltage-dependent anion channel (VDAC) to directly induce mitochondrial release and nuclear translocation of EndonucleaseG. Data has identified VDAC as an interacting partner of BNIP3 and provide direct evidence to support that EndoG is a mediator of the BNIP3 cell death pathway. Most notably, Enodnuclease G is pivotal during oxidative stress by ischemia-reperfusion injury, specifically in the myocardium as part of a heart attack (also known as ischemic heart disease).
The total fertility rate for the country was 2.3 in rural areas whereas it has been 1.8 in urban areas during 2015. The most common cause of disability adjusted life years lost for Indian citizens as of 2016 for all ages and sexes was ischemic heart disease (accounting for 8.66% of total DALYs ), 2nd chronic obstructive pulmonary disease (accounting for 4.81% of total DALYs), 3rd diarrhea (accounting for 4.64% of total DALYs) and 4th lower respiratory infections (accounting for 4.35% of total DALYs).
When performed as a primary therapy, it is done through a small incision between the ribs (thoracotomy) with the patient under general anesthesia. Transmyocardial laser revascularization (TMR) can also be performed as a secondary procedure in patients that have ischemic heart disease with areas of the heart that cannot be bypassed. The precise laser therapy is delivered to create small channels into the heart chamber. During a typical procedure, approximately 10 –50 channels are made in each targeted region of the heart muscle.
Associated disorders include intellectual disabilities, seizures, muscle contractures, abnormal gait, osteoporosis, communication disorders, malnutrition, sleep disorders, and mental health disorders, such as depression and anxiety. In addition to these, functional gastrointestinal abnormalities contributing to bowel obstruction, vomiting, and constipation may also arise. Adults with cerebral palsy may have ischemic heart disease, cerebrovascular disease, cancer, and trauma more often. Obesity in people with cerebral palsy or a more severe Gross Motor Function Classification System assessment in particular are considered risk factors for multimorbidity.
Most SVTs are unpleasant rather than life-threatening, although very fast heart rates can be problematic for those with underlying ischemic heart disease or the elderly. Episodes require treatment when they occur, but interval therapy may also be used to prevent or reduce recurrence. While some treatment modalities can be applied to all SVTs, there are specific therapies available to treat some sub-types. Effective treatment consequently requires knowledge of how and where the arrhythmia is initiated and its mode of spread.
It can be seen in myocardial ischemia, propranolol use, digitalis use, rheumatic fever, and chronically in ischemic heart disease and other structural diseases (amyloidosis, mitral valve prolapse, aortic valve disease, and atrial septal defect). In symptomatic cases, intravenous atropine or isoproterenol may transiently improve conduction.Lilly, L. S., Pathophysiology of Heart Disease. Baltimore: Lippincott Williams & Wilkins; 2007 Sinus rhythm with acute inferior infarction complicated by Type I A-V block manifest in the form of 5:4 Wenckebach periods; R-P/P-R reciprocity.
According to ICD-10, hypertensive heart disease (I11), and its subcategories: hypertensive heart disease with heart failure (I11.0) and hypertensive heart disease without heart failure (I11.9) are distinguished from chronic rheumatic heart diseases (I05-I09), other forms of heart disease (I30-I52) and ischemic heart diseases (I20-I25). However, since high blood pressure is a risk factor for atherosclerosis and ischemic heart disease, death rates from hypertensive heart disease provide an incomplete measure of the burden of disease due to high blood pressure.
According to a study, life expectancy for Egyptians decreases by 1.85 years due to the level of air pollution, one of the worst ranked in the world. Breath Life estimates there are 67,283 annual deaths from air pollution, with the leading cause being Ischemic heart disease. The water in Egypt has also been found to contain heavy metal contaminants which can be harmful to health. Lower Egypt releases the most waste into the Nile, it being the most populous, industrial and agricultural country in the basin.
Starr was found dead at his home in Mijas, on the Costa Del Sol, Spain, on 9 May 2019, aged 76. A post-mortem showed that he died from ischemic heart disease. At the time of his death Starr was living in constrained financial circumstances, and his funeral costs were covered by an undertaker from Sheffield. The funeral was held at Prescot Parish Church on Merseyside on 13 June 2019, with his body being buried in a family-owned grave in a cemetery at Huyton.
Stem cells have always been a huge interest for scientists due to their unique properties that make them unlike any other cell in the body. Generally, the idea boils down to harnessing the power of plasticity and the ability to go from an unspecialized cell to a highly specialized differentiated cell. ESCs play an incredibly important role in establishing the vascular network that is vital for a functional circulatory system. Consequently, EPCs are under study to determine the potential for treatment of ischemic heart disease.
Cardiac disease in China is on the rise. Though incidences of heart disease have increased faster in the city than in the countryside, rural morbidity and mortality rates are now on the rise as well. Health statistics shows that the ischemic heart disease mortality rate in rural China has approximately doubled since 1988.Cardiac Disease and Health Care in China China-California Heart Watch Unlike in developed countries, there is no preventive or primary health care system in place to stop the rise of cardiac disease.
This test can be used to diagnose coronary artery disease (also known as ischemic heart disease) and assess patient prognosis after a myocardial infarction (heart attack). Exercise-induced stressors are most commonly either exercise on a treadmill or pedalling a stationary exercise bicycle ergometer. The level of stress is progressively increased by raising the difficulty (steepness of the slope on a treadmill or resistance on an ergometer) and speed. People who cannot use their legs may exercise with a bicycle-like crank that they turn with their arms.
Numerous studies have been dedicated towards the development of effective methods to enable cardiac tissue regeneration in patients after ischemic heart disease. An emerging approach to answer the problems related to ischemic tissue repair is through the use of stem cell- based therapy. However, the actual mechanism due to which this stem cell-based therapy has generative effects on cardiac function is still under investigation. Even though numerous methods have been studied for cell administration, the efficiency of the number of cells retained in the beating heart after implantation is still very low.
With positive outcomes following cardiac arrest unlikely, an effort has been spent in finding effective strategies to prevent cardiac arrest. With the prime causes of cardiac arrest being ischemic heart disease, efforts to promote a healthy diet, exercise, and smoking cessation are important. For people at risk of heart disease, measures such as blood pressure control, cholesterol lowering, and other medico-therapeutic interventions are used. A Cochrane review published in 2016 found moderate- quality evidence to show that blood pressure-lowering drugs do not appear to reduce sudden cardiac death.
Decreased LINE-1 methylation is a strong predictive indicator of ischemic heart disease and stroke, although the mechanism is unknown. Various impairments in lipid metabolism, leading to clogging of arteries, has been associated with the hypermethylation of GNASAS, IL-10, MEG3, ABCA1, and the hypomethylation of INSIGF and IGF2. Additionally, upregulation of a number of miRNAs has been shown to be associated with acute myocardial infarction, coronary artery disease, and heart failure. Strong research efforts into this area are very recent, with all of the aforementioned discoveries being made since 2009.
This arrhythmia can be underlain by several causes, which are best divided into cardiac and non-cardiac causes. Non- cardiac causes are usually secondary, and can involve recreational drug use or abuse; metabolic or endocrine issues, especially hypothyroidism; an electrolyte imbalance; neurologic factors; autonomic reflexes; situational factors such as prolonged bed rest; and autoimmunity. Cardiac causes include acute or chronic ischemic heart disease, vascular heart disease, valvular heart disease, or degenerative primary electrical disease. Ultimately, the causes act by three mechanisms: depressed automaticity of the heart, conduction block, or escape pacemakers and rhythms.
Since HIGD1A promotes cell survival under hypoxia, the protein protects organs like the heart and brain from hypoxia-related diseases. In particular, HIGD1A localization to the nucleus correlates with the severity of stress in ischemic heart disease, hypoxic-ischemic encephalopathy, and cancer, and thus may serve as a biomarker for these diseases. Moreover, HIGD1A is involved in inflammatory diseases, such as atherosclerosis and rheumatoid arthritis, through its role in macrophage survival. Similarly, HIGD1A could become a key target for treating Alzheimer’s disease by inhibiting γ-secretase, and by extension, amyloid beta production.
Total recorded alcohol per capita consumption, in litres of pure alcohol. Excessive alcohol intake is associated with an elevated risk of alcoholic liver disease (ALD), heart failure, some cancers, and accidental injury, and is a leading cause of preventable death in industrialized countries. However, extensive research has shown that moderate alcohol intake is associated with health benefits, including less cardiovascular disease, diabetes, and hypertension. Epidemiological and short term experimental studies have shown drinkers who consume one to two drinks per drinking day have a beneficial association with ischemic heart disease compared to never-drinkers.
Echocardiogram shows left ventricular dilatation with normal or thinned walls and reduced ejection fraction. Cardiac catheterization and coronary angiography are often performed to exclude ischemic heart disease. Genetic testing can be important, since one study has shown that gene mutations in the TTN gene (which codes for a protein called titin) are responsible for "approximately 25% of familial cases of idiopathic dilated cardiomyopathy and 18% of sporadic cases." The results of the genetic testing can help the doctors and patients understand the underlying cause of the dilated cardiomyopathy.
Quite a number of members of the Seventh-day Adventist Church also avoid caffeinated drinks. In its teachings, the Church encourages members to avoid tea, coffee, and other stimulants. Abstinence from coffee, tobacco, and alcohol by many Adventists has afforded a near-unique opportunity for studies to be conducted within that population group on the health effects of coffee drinking, free from confounding factors. One study showed a weak but statistically significant association between coffee consumption and mortality from ischemic heart disease, other cardiovascular disease, all cardiovascular diseases combined, and all causes of death.
The risks of developing a life-threatening disease affecting the heart or brain increase as the blood flow increases. Commonly, ischemic heart attack and stroke are the causes that lead to death in patients with severe hypertension. It is estimated that for every 20 mm Hg systolic or 10 mm Hg diastolic increase in blood pressures above 115/75 mm Hg, the mortality rate for both ischemic heart disease and stroke doubles. Consequences of hypertensive emergency result after prolonged elevations in blood pressure and associated end-organ dysfunction.
Cardiovascular diseases comprise 38% of all deaths in Tajikistan, compared to 8% for cancers, 4% for respiratory diseases, 1% for diabetes and 11% for other NCDs. From 1990 to 2013, the three leading causes of death from NCDs in Tajikistan have remained the same: ischemic heart disease, cerebrovascular disease, and COPD.Global Burden of Disease, 2013 The main risk factors for NCD deaths in Tajikistan are dietary risks, high blood pressure and high body mass index. An estimated 40% of the population in Tajikistan is overweight and 9% is obsese.
In fact, potential beneficial effects on cardiovascular mortality have been observed at this dosage. However, PEP at a higher dosage of 240 mg/month has subsequently been found in large studies to significantly increase cardiovascular morbidity relative to GnRH modulators and orchiectomy in men treated with it for prostate cancer. The increase in cardiovascular morbidity with PEP therapy is due to an increase in non-fatal cardiovascular events, including ischemic heart disease and heart decompensation, specifically heart failure. Conversely, PEP has not been found to significantly increase cardiovascular mortality relative to GnRH modulators and orchiectomy.
There are two types of angiopathy: macroangiopathy and microangiopathy. In macroangiopathy, atherosclerosis and a resultant blood clot forms on the large blood vessels, sticks to the vessel walls, and blocks the flow of blood. Macroangiopathy may cause other complications, such as ischemic heart disease, stroke and peripheral vascular disease which contributes to the diabetic foot ulcers and the risk of amputation. In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood through the body.
Forrester directed a multimillion- dollar National Institute of Health research program called a Specialized Center of Research in Ischemic Heart Disease at Cedars-Sinai Medical Center. During this 20-year period Cedars-Sinai cardiology was ranked first in the western United States by U.S. News and World Report, a position which it continues to hold through the present day. Forrester's research led to three advances that altered the practice of cardiology. In the 1970s, he directed the development of hemodynamic monitoring at the bedside, using a balloon- tipped catheter he maneuvered through the heart.
The most common non-infectious diseases worldwide, that contribute most to the global mortality rate, are cardiovascular diseases, various cancers, diabetes, and chronic respiratory problems, all of which are linked to poor nutrition. Nutrition and diet are closely associated with the leading causes of death, including cardiovascular disease and cancer. Obesity and high sodium intake can contribute to ischemic heart disease, while consumption of fruits and vegetables can decrease the risk of developing cancer. Food-borne and infectious diseases can result in malnutrition, and malnutrition exacerbates infectious disease.
A plausible treatment for patients with this disease is revascularization,which would restore blood supply to the heart. MiR-27b is linked to Semaphorin 6A, which is an inhibitor of angiogenesis. Overexpression of miR-27b decreased the protein expression of Semaphorin 6A which favored new blood vessel sprouting in the heart. To further determine that Semaphorin 6A is an inhibitor of angiogenesis, silencing of Semaphorin 6A using siRNA showed an increase in blood vessel formation further proven that mir-27b might be useful in treating patients with ischemic heart disease.
Hkun Htun Oo and the other Shan State leaders were sent to different prisons in remote area of Burma, hundreds of miles from their hometowns.From 2005 to 2011, Hkun Htun Oo was held in Putao prison in Northernmost Kachin State where temperature fall below zero in winter . According to reports released from the prison, despite having diabetes and gout he received little medical attention, and was also suffering from swollen legs due to lack of exercise, as well as ischemic heart disease. Amnesty International reported that he also suffers from a peptic ulcer and arthritis.
Treatments include changing approaches to eating such as cutting food in advance to make eating easier and less likely to avoid as well as consumer health products such as multivitamins and multi- minerals specifically designed to support the nutritional issues experienced by denture wearers. Numerous studies linking edentulism with instances of disease and medical conditions have been reported. In a cross-sectional study, Hamasha and others found significant differences between edentulous and dentate individuals with respect to rates of atherosclerotic vascular disease, heart failure, ischemic heart disease and joint disease.
Three years later he founded the influential Mackenzie Institute of Clinical Research in St Andrews, which involved local General Practitioners in detailed long-term recording of patients' symptoms and illnesses. Ironically Mackenzie himself suffered from an irregular heart beat, as a result of ischemic heart disease. He had his first heart attack in 1901, and recorded in himself the atrial fibrillation that accompanied this episode. By 1907 Mackenzie experienced frequent episodes of angina pectoris which he mentioned to Sir Thomas Lewis and in 1908 he had a severe episode of cardiac pain, probably due to a myocardial infarction.
Ticlopidine was discovered in the 1970s in France by a team led by Fernand Eloy and including Jean-Pierre Maffrand at Castaigne SA that was trying to discover a new anti-inflammatory medication. Pharmacology developers noted that this new compound had strong anti-platelet properties. Castaigne was acquired by Sanofi in 1973. Starting in 1978 the drug was marketed in France under the brand name Ticlid for people at high risk for thrombotic events, who had just come out of heart surgery, were undergoing hemodialysis, had peripheral vascular disease, or who were otherwise at risk for strokes and ischemic heart disease.
A 23-year prospective study of 12,000 male British physicians aged 48–78, found that overall mortality was significantly lower in current drinkers compared to non-drinkers even after correction for ex-drinkers. This benefit was strongest for ischemic heart disease, but was also noted for other vascular disease and respiratory disease. Death rate amongst current drinkers was higher for 'alcohol augmentable' disease such as liver disease and oral cancers, but these deaths were much less common than cardiovascular and respiratory deaths. The lowest mortality rate was found for consumption of 8 to 14 'units' per week.
Nitroglycerin belongs to a group of drugs called nitrates, which includes many other nitrates like isosorbide dinitrate (Isordil) and isosorbide mononitrate (Imdur, Ismo, Monoket). These agents all exert their effect by being converted to nitric oxide in the body by mitochondrial aldehyde dehydrogenase (ALDH2), and nitric oxide is a potent natural vasodilator. Nitroglycerin in three different forms: intravenous, sublingual spray, and the nitroglycerin patch. In medicine, nitroglycerin is used for angina pectoris, a painful symptom of ischemic heart disease caused by inadequate flow of blood and oxygen to the heart and as a potent antihypertensive agent.
Type 2 diabetes is typically a chronic disease associated with a ten-year-shorter life expectancy. This is partly due to a number of complications with which it is associated, including: two to four times the risk of cardiovascular disease, including ischemic heart disease and stroke; a 20-fold increase in lower limb amputations, and increased rates of hospitalizations. In the developed world, and increasingly elsewhere, type 2 diabetes is the largest cause of nontraumatic blindness and kidney failure. It has also been associated with an increased risk of cognitive dysfunction and dementia through disease processes such as Alzheimer's disease and vascular dementia.
How Loud is Too Loud - Various common noise levels and when noise becomes hazardous to hearing and well-being Noise health effects are the physical and psychological health consequences of regular exposure to consistent elevated sound levels. Noise from traffic, in particular, is considered by the World Health Organization to be one of the worst environmental stressors for humans, second only to air pollution. Elevated workplace or environmental noise can cause hearing impairment, tinnitus, hypertension, ischemic heart disease, annoyance, and sleep disturbance. Changes in the immune system and birth defects have been also attributed to noise exposure.
A 2011 report by the Ghana Health Service said that malaria was the primary cause of morbidity and about 32.5 percent of people admitted to Ghanaian medical facilities were admitted because of malaria. The most recent report from the WHO in 2012 identifies the top causes of death in Ghana as lower respiratory infections (11%), Stroke (9%), Malaria (8%), ischemic heart disease (6%), HIV/AIDS (5%), preterm birth complications (4%), birth asphyxia and birth trauma (4%), meningitis (3%), and protein-energy malnutrition (3%). The life expectancy for women is 63 years while for men, it is 60 years. The infant mortality rate is 41 out of every 1000 live births.
As the radionuclide redistributes slowly, it is not usually possible to perform both sets of images on the same day, hence a second attendance is required 1–7 days later (although, with a Tl-201 myocardial perfusion study with dipyridamole, rest images can be acquired as little as two-hours post stress). However, if stress imaging is normal, it is unnecessary to perform rest imaging, as it too will be normal – thus stress imaging is normally performed first. MPI has been demonstrated to have an overall accuracy of about 83% (sensitivity: 85%; specificity: 72%), and is comparable (or better) than other non-invasive tests for ischemic heart disease, including stress echocardiography.
Insufficient physical activity (defined as less than 5 x 30 minutes of moderate activity per week, or less than 3 x 20 minutes of vigorous activity per week) is currently the fourth leading risk factor for mortality worldwide. In 2008, 31.3% of adults aged 15 or older (28.2% men and 34.4% women) were insufficiently physically active. The risk of ischemic heart disease and diabetes mellitus is reduced by almost a third in adults who participate in 150 minutes of moderate physical activity each week (or equivalent). In addition, physical activity assists weight loss and improves blood glucose control, blood pressure, lipid profile and insulin sensitivity.
Large amounts of noise pollution not only lead to lower property values and high frustration, they can be damaging to human hearing and health. In the study “Noise exposure and public health,” they argue that exposure to continual noise is a public health problem. They cite examples of the detriment of continual noise on humans to include: “hearing impairment, hypertension and ischemic heart disease, annoyance, sleep disturbance, and decreased school performance.” Since most roofs or vacant lots consist of hard flat surfaces that reflect sound waves instead of absorbing them, adding plants that can absorb these waves has the potential to lead to a vast reduction in noise pollution.
Dobutamine is used to treat acute but potentially reversible heart failure, such as which occurs during cardiac surgery or in cases of septic or cardiogenic shock, on the basis of its positive inotropic action. Dobutamine can be used in cases of congestive heart failure to increase cardiac output. It is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility, which could be the result of either organic heart disease or cardiac surgical procedures. It is not useful in ischemic heart disease because it increases heart rate and thus increases myocardial oxygen demand.
Rates of death from ischemic heart disease (IHD) have slowed or declined in most high-income countries, although cardiovascular disease still accounted for one in three of all deaths in the US in 2008. For example, rates of death from cardiovascular disease have decreased almost a third between 2001 and 2011 in the United States. In contrast, IHD is becoming a more common cause of death in the developing world. For example, in India, IHD had become the leading cause of death by 2004, accounting for 1.46 million deaths (14% of total deaths) and deaths due to IHD were expected to double during 1985–2015.
Lasmiditan is a serotonin receptor agonist that, like the unsuccessful LY-334,370, selectively binds to the 5-HT1F receptor subtype. A number of triptans have been shown to act on this subtype as well, but only after their affinity for 5-HT1B and 5-HT1D has been made responsible for their anti- migraine activity. The lack of affinity for these receptors might result in fewer side effects related to vasoconstriction compared to triptans in susceptible people, such as those with ischemic heart disease, Raynaud's phenomenon or after a myocardial infarction, although a 1998 review has found such side-effects to rarely occur in people taking triptans.
Sam Lister The price of alcohol: an extra 6,000 early deaths a year The Times, 19 October 2009 A UK report came to the result that the effects of low-to-moderate alcohol consumption on mortality are age-dependent. Low-to- moderate alcohol use increases the risk of death for individuals aged 16–34 (due to increased risk of cancers, accidents, liver disease, and other factors), but decreases the risk of death for individuals ages 55+ (due to decreased risk of ischemic heart disease). A study in the United Kingdom found that alcohol causes about 4% of cancer cases in the UK (12,500 cases per year).
The lack of an adequate venous conduit is a relative contraindication to bypass surgery, and depending on the area of disease, alternatives may be used. Medical conditions such as ischemic heart disease or chronic obstructive pulmonary disease that increase the risk of surgery are also relative contraindications. For coronary and peripheral vascular disease, lack of "runoff" to the distal area is also a contraindication because a vascular bypass around one diseased artery to another diseased area does not solve the vascular problem. If a patient is deemed to be too high-risk to undergo a bypass, he or she may be a candidate for angioplasty or stenting of the relevant vessel.
The DOHaD approach originated in studies by David Barker and his colleagues, which showed a strong relationship between infant mortality rates from 1921 to 1925 and ischemic heart disease rates from 1968 to 1978. This led to the fetal origins hypothesis of the origins of adult diseases, which proposed that this relationship was caused by differences in early life nutrition. This in turn led to greater interest in the roles of developmental plasticity and early life environmental exposures in adult disease. The World Congress on Fetal Origins of Adult Disease held two meetings – one in 2001 and the other in 2003 – summarizing then-new research in these areas.
The decades that followed (1982 to 2002) saw Professor Ye.I. Sokolov as the Rector. As head of the Internal Disease department, he became known for his research into the problems of ischemic heart disease, correction of hemostasis disturbances, and clinical psychophysiology, which brought him success and were immediately put to medical use. Under Professor Ye.I. Sokolov's leadership, the Dentistry faculty premises were greatly enlarged and new departments were added to both Dentistry and General Medicine faculties, as well as output of graduates increased. In 1986, а part-time faculty for dental students was opened, in 1995 - one for post-graduate students, and, in 1998, a secondary medical education faculty was launched to train dental mechanics.
All those who died had comorbidities and other relatively serious health problems ranging from only diabetes mellitus in one person (aged 35) to complicated combinations of diabetes mellitus, hypertension and ischemic heart disease in two (65 and 80 years old) and diabetes mellitus, hypertension and nephropathy in another one who was 73 years old. Another patient who died and was 64 years old, had diabetes mellitus and hypertension. All those who died were males and three of them were reported to have had contact with, and exposure to, camels. Among the nine persons who survived were two females who were believed to have had contact with a person infected with MERS, one being a 23-year-old healthcare worker.
Unlike our definitions of ischemic heart disease, > lymphoma, or AIDS, the DSM diagnoses are based on a consensus about clusters > of clinical symptoms, not any objective laboratory measure. In the rest of > medicine, this would be equivalent to creating diagnostic systems based on > the nature of chest pain or the quality of fever. Given that addiction manifests in structural changes to the brain, it is possible that non-invasive neuroimaging scans obtained via MRI could be used to help diagnose addiction in the future. As a diagnostic biomarker, ΔFosB expression could be used to diagnose an addiction in humans, but this would require a brain biopsy and therefore is not used in clinical practice.
Ischemic heart disease, which results from an occlusion of one of the major coronary arteries, is currently still the leading cause of morbidity and mortality in western society. During ischemia reperfusion, ROS release substantially contribute to the cell damage and death via a direct effect on the cell as well as via apoptotic signals. More recently, Endonuclease G is considered a determinant of cardiac hypertrophy. A link has been established between Endonuclease G and mitochondrial function during cardiac hypertrophy, partly through the effects of Endo G on Mfn2 and Jp2, and revealed a role for Endonuclease G in the crosstalk between the processes controlled by Mfn2 and Jp2 in maladaptive cardiac hypertrophy.
The most common cause of MR in developing countries is mitral valve prolapse (MVP). It is the most common cause of primary mitral regurgitation in the United States, causing about 50% of cases. Myxomatous degeneration of the mitral valve is more common in women as well as with advancing age, which causes a stretching of the leaflets of the valve and the chordae tendineae. Such elongation prevents the valve leaflets from fully coming together when the valve closes, causing the valve leaflets to prolapse into the left atrium, thereby causing MR. Ischemic heart disease causes MR by the combination of ischemic dysfunction of the papillary muscles, and the dilatation of the left ventricle.
These conditions include but are not limited to high blood pressure, pre-existing cardiovascular disease (such as valvular heart disease or ischemic heart disease), history of thromboembolism or pulmonary embolism, cerebrovascular accident, migraine with aura, a familial tendency to form blood clots (such as familial factor V Leiden), and in smokers over age 35. COCPs are also contraindicated for people with advanced diabetes, liver tumors, hepatic adenoma or severe cirrhosis of the liver. COCPs are metabolized in the liver and thus liver disease can lead to reduced elimination of the medication. People with known or suspected breast cancer, endometrial cancer, or unexplained uterine bleeding should also not take COCPs to avoid health risks.
Acorn soup A fruit stall in Barcelona Basket of fresh fruit and vegetables grown in Israel Studies on the health effects of vegetarian diets observe mixed effects on mortality. One review found a decreased overall risk of all cause mortality, cancer (except breast) and cardiovascular disease; however, a meta-analysis found lower risk for ischemic heart disease and cancer but no effect on overall mortality or cerebrovascular disease. Possible limitations include varying definitions used of vegetarianism, and the observation of increased risk of lung cancer mortality in those on a vegetarian diet for less than five years. An analysis pooling two large studies found vegetarians in the UK have similar all cause mortality as meat eaters.
Some preliminary studies link low vitamin D levels with disease later in life. One meta-analysis found a decrease in mortality in elderly people. Another meta-analysis covering over 350,000 people concluded that vitamin D supplementation in unselected community- dwelling individuals does not reduce skeletal (total fracture) or non-skeletal outcomes (myocardial infarction, ischemic heart disease, stroke, cerebrovascular disease, cancer) by more than 15%, and that further research trials with similar design are unlikely to change these conclusions. A 2019 meta-analysis found that there may be an increased risk of stroke when taking both calcium and vitamin D. Evidence as of 2013 is insufficient to determine whether vitamin D affects the risk of cancer.
In 1997, after reviewing 33 clinical studies performed over the previous decades, the FDA approved the claim that intaking at least 3 g of β-glucan from oats per day decreased saturated fats and reduced the risk of heart disease. This marked the first time a public health agency claimed dietary intervention can actually help prevent disease. This health claim mobilized a dietary movement as physicians and dietitians for the first time could recommend intake of a specific food to directly combat disease. Since then, oat consumption has continued to gain traction in disease prevention with noted effects on ischemic heart disease and stroke prevention, but also in other areas like BMI reduction, blood pressure lowering and highly corroborated evidence for reduced blood serum cholesterol.
It has been estimated to account for 5-25% of all imaging costs. Patient demand often stems from little financial responsibility for costs associated with imaging, as well as information from other individuals, radio, the media, and the Internet with disproportionate understanding of the implications of imaging (further testing, exposure to radiation). Patients are being targeted to "self-present" to imaging facilities for uncovered imaging services that claim to offer screen for undetected coronary artery disease and cancer in the lungs and other organs. However, the false positives observed for CT screening of coronary artery disease are similar to the levels of other noninvasive tests for ischemic heart disease and some data indicate these services do not yield more precise results.
The cancer cells in these patients are typically smaller than regular cancer cells, but they multiply rapidly to generate massive tumors. The second type is called Non-Small Cell Lung Cancer and is responsible for 80% of call cancer cases. Cancers such as the Squamous cell carcinoma in men and Adenocarcinoma in women are the two most common form of NSCLC. The estimated average annual number of smoking-attributable deaths in the United States during 2000 through 2004 by specific causes, as follows: lung cancer: 128,900 deaths, other cancers: 35,300 deaths, ischemic heart disease: 126,000 deaths, chronic obstructive pulmonary disease: 92,900 deaths, stroke: 15,900 deaths and other diagnoses: 44,000 deaths Second-hand smoke is also another major problem from cigarettes, and it has the same effects on nonsmokers as it does to smokers.
A systematic analysis of data from the Global Burden of Disease Study, which was an observational study, found that long-term consumption of any amount of alcohol is associated with an increased risk of death in all people, and that even moderate consumption appears to be risky. Similar to prior analyses, it found an apparent benefit for older women in reducing the risks of death from ischemic heart disease and from diabetes, but unlike prior studies it found those risks cancelled by an apparent increased risk of death from breast cancer and other causes. A 2016 systematic review and meta-analysis found that moderate ethanol consumption brought no mortality benefit compared with lifetime abstention from ethanol consumption. Risk is greater in younger people due to heavy episodic drinking which may result in violence or accidents.
Publications by the United States Public Health Service have shown that Vietnam veterans, overall, have increased rates of cancer, and nerve, digestive, skin, and respiratory disorders. The Centers for Disease Control and Prevention notes that in particular, there are higher rates of acute/chronic leukemia, Hodgkin's lymphoma and non-Hodgkin's lymphoma, throat cancer, prostate cancer, lung cancer, colon cancer, Ischemic heart disease, soft tissue sarcoma, and liver cancer. With the exception of liver cancer, these are the same conditions the U.S. Veterans Administration has determined may be associated with exposure to Agent Orange/dioxin and are on the list of conditions eligible for compensation and treatment. Military personnel who were involved in storage, mixture and transportation (including aircraft mechanics), and actual use of the chemicals were probably among those who received the heaviest exposures.
The health problems associated with cooking using biomass in traditional stoves affect women and children most strongly, as they spend the most time near the domestic hearth. Replacing the traditional 3-rock cook stove or mud stove with an improved one and venting the smoke out of the house through a chimney can significantly improve a family's health. There are many well-documented adverse health effects of exposure to pollutants from indoor cookstoves, including acute respiratory infections (ARIs), chronic obstructive pulmonary disease (COPD), pulmonary tuberculosis (TB), cataracts, low birth weight (LBW), increased perinatal and infant mortality, nasopharyngeal and laryngeal cancer, and lung cancer. It is estimated that 4% to 5% of the global mortality and disability adjusted life- years (DALYs) are from ARIs, COPD, TB, asthma, lung cancer, ischemic heart disease, and blindness attributed to solid fuel combustion when cooking in developing countries.
This list now includes B cell leukemias, such as hairy cell leukemia, Parkinson's disease and ischemic heart disease, these last three having been added on August 31, 2010. Several highly placed individuals in government are voicing concerns about whether some of the diseases on the list should, in fact, actually have been included. In 2011, an appraisal of the 20 year long Air Force Health Study that began in 1982 indicates that the results of the AFHS as they pertain to Agent Orange, do not provide evidence of disease in the Operation Ranch Hand veterans caused by "their elevated levels of exposure to Agent Orange". The VA initially denied the applications of post-Vietnam C-123 aircrew veterans because as veterans without "boots on the ground" service in Vietnam, they were not covered under VA's interpretation of "exposed".
Family history of ischemic heart disease or MI, particularly if one has a male first-degree relative (father, brother) who had a myocardial infarction before age 55 years, or a female first-degree relative (mother, sister) less than age 65 increases a person's risk of MI. Genome-wide association studies have found 27 genetic variants that are associated with an increased risk of myocardial infarction. The strongest association of MI has been found with chromosome 9 on the short arm p at locus 21, which contains genes CDKN2A and 2B, although the single nucleotide polymorphisms that are implicated are within a non-coding region. The majority of these variants are in regions that have not been previously implicated in coronary artery disease. The following genes have an association with MI: PCSK9, SORT1, MIA3, WDR12, MRAS, PHACTR1, LPA, TCF21, MTHFDSL, ZC3HC1, CDKN2A, 2B, ABO, PDGF0, APOA5, MNF1ASM283, COL4A1, HHIPC1, SMAD3, ADAMTS7, RAS1, SMG6, SNF8, LDLR, SLC5A3, MRPS6, KCNE2.
A study conducted by the International Journal of Behavioral Medicine re-examined the association between the Type A concept with cardiovascular (CVD) and non- cardiovascular (non-CVD) mortality by using a long follow-up (on average 20.6 years) of a large population-based sample of elderly males (N = 2,682), by applying multiple Type A measures at baseline, and looking separately at early and later follow-up years. The study sample were the participants of the Kuopio Ischemic Heart Disease Risk Factor Study, (KIHD), which includes a randomly selected representative sample of Eastern Finnish men, aged 42–60 years at baseline in the 1980s. They were followed up until the end of 2011 through linkage with the National Death Registry. Four self-administered scales, Bortner Short Rating Scale, Framingham Type A Behavior Pattern Scale, Jenkins Activity Survey, and Finnish Type A Scale, were used for Type A assessment at the start of follow-up.
Alexander V. Nichols, Robert M. Glaeser, Howard C. Mel, In Memoriam - John Gofman , University of California Leslie J. Freeman, John W. Gofman - Medical Physicist, in Nuclear Witnesses - Insiders speak out, 1981, p 85 John W. Gofman with Egan O'Connor, Radiation from Medical Procedures in the Pathogenesis of Cancer and Ischemic Heart Disease: Dose-Response Studies with Physicians per 100,000 Population, The Author's History , Committee for Nuclear Responsibility, 1999 John Gofman, PhD dissertation, The discovery of Pa-232, U-232, Pa-233, and U-233. The slow and fast neutron fissionability of U-233. Obituary: John W. Gofman, 88, Scientist and Advocate for Nuclear Safety Dies New York Times, August 26, 2007. US DOE Office of Human Radiation Experiments, Oral history of Dr. John W. Gofman Curriculum Vitae of Dr. John W. Gofman, in "Preventing Breast Cancer: The Story of a Major, Proven, Preventable Cause of this Disease", 2nd edition, 1996, p 379-381 Ioanna Semendeferi, "Legitimating a Nuclear Critic: John Gofman, Radiation Safety, and Cancer Risks", Historical Studies in the Natural Sciences, Vol.
The leading causes of mortality for all age groups are cerebrovascular diseases (11.6%); ischemic heart disease (9.9%); immunity disorders (7.1%); diseases of the respiratory system (6.8%); diseases of pulmonary circulation and other forms of heart disease (6.6%); endocrine and metabolic diseases (5.5%); diseases of other parts of the Digestive System (5.2%); violence (5.1%); certain condition originating in the prenatal period (4.3%); and hypertensive diseases (3.9%). The ten leading causes of morbidity for all age groups are, in decreasing order: malaria; acute respiratory infections; symptoms, signs and ill defined or unknown conditions; hypertension; accident and injuries; acute diarrhoeal disease; diabetes mellitus; worm infestation; rheumatic arthritis; and mental and nervous disorders. This morbidity profile indicates that it can be improved substantially through enhanced preventive health care, better education on health issues, more widespread access to potable water and sanitation services, and increased access to basic health care of good quality. A number of non-governmental organisations, including Health and Educational Relief for Guyana (HERG, INC) and Guyana Medical Relief (GMR, INC) are currently working to address these issues by improving healthcare access and educational infrastructure.
Berkeley: University of California Press, 2006, p. 188. She observes that mean serum cholesterol in Israel is quite low by the standards of developed countries: 210 milligrams/dl. Therefore, one distinction that can, without controversy, be attributed to the high levels of linoleic acid in the Israeli diet is the high percentage of linoleic acid in the adipose tissue of Israelis: 24% as compared to 16% in Americans and less than 10% in many northern Europeans.Susan Allport, The Queen Of Fats: Why Omega-3s Were Removed From The Western Diet And What We Can Do To Replace Them. Berkeley: University of California Press, 2006, p. 188. In 1993, a 23-year follow-up study to the Israeli Ischemic Heart Disease Study of ten thousand public service employees (widely referred to as the “Israeli Civil Service Study”Nina Teicholz, The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet New York: Simon and Schuster, 2014, p. 97.) found that there were only “weak associations of long-term coronary mortality with the dietary intake patterns of fatty acids.”U.
In the UK a unit is defined as 10ml or 8g of pure alcohol. Higher consumption increased overall mortality rate, but not above that of non-drinkers. Other studies have found age-dependent mortality risks of low-to-moderate alcohol use: an increased risk for individuals aged 16–34 (due to increased risk of cancers, accidents, liver disease, and other factors), but a decreased risk for individuals ages 55+ (due to lower incidence of ischemic heart disease). This is consistent with other research that found a J-curve dependency between alcohol consumption and total mortality among middle aged and older men. While the mortality rates of ex-drinkers and heavy drinkers are significantly elevated, the all-cause mortality rates may be 15–18% lower among moderate drinkers. Although the definition of a drink varies between studies and countries, this meta-analysis found that low levels of alcohol intake, defined as 1–2 drinks per day for women and 2–4 drinks per day for men, was associated with lower mortality than abstainers.

No results under this filter, show 185 sentences.

Copyright © 2024 RandomSentenceGen.com All rights reserved.