He encouraged this immortalization, producing, for instance, furry Fendi dolls in his likeness.
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Jason Leach's preferred method of immortalization is to press his ashes into vinyl.
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She is challenging the onlooker by validating the experiences of those that she shoots through her loving immortalization of their lives with her camera.
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"Science is like religion, an effort at transcendance that ends by accepting a world that is beyond understanding," John Gray writes in The Immortalization Commission.
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Fully embracing his immortalization via meme, Justin Timberlake, the comedic class act that he is, joined in last year with a tweet saying, "EVERYBODY... IT IS ACTUALLY GONNA BE MAY!"
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LONDON — Rare footage that shows Queen Victoria smiling, sporting sunglasses and greeting the public has been rediscovered, challenging history's immortalization of the British monarch as an imposing and sullen figure.
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Volpe's work oscillates between the actions of the living, who appear poignantly in pops of color picking up the pieces, and the immortalization of the dead and destroyed covered in thick, gray, mud.
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Is it that these figures truly turn away from society, eschewing it for a "purer" form of life and practice, or is their disappearance more tantamount to an alternative career move, an immortalization in obscurity?
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It's rooted in the eccentric wisdom of a small, furniture-obsessed religious sect founded in the 18th century that has all but disappeared, apart from its immortalization in a Ken Burns documentary and prominence in museum collections.
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CaMKII has recently been implicated in the immortalization of the ΔFosB protein in accumbal dopaminergic neurons, making it a large contributor to the stabilization of the addictive state.
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Small animals, like cats, experience faster rates of cancer development. As a result, they are good preclinical models for understanding processes like immortalization and its role in promoting cancerous tumors.
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Her interests evolved to examining cellular immortalization in cancer cells, and the role of telomeres in this process. She published her last paper in 1998. Vogt made significant contributions as a scientist in multiple areas: as a Drosophila developmental geneticist, as a virologist working with Nobel laureate Renato Dulbecco, and as an investigator into viral transformation and cellular immortalization. Moreover, she was an influential mentor and colleague to many junior scientists, among them several future Nobel laureates.
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Viral transformation can impose characteristically determinable features upon a cell. Typical phenotypic changes include high saturation density, anchorage-independent growth, loss of contact inhibition, loss of orientated growth, immortalization, disruption of the cell's cytoskeleton.
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Leonid Krasin (on right) with 198x198px Krasin, in the tradition of Nikolai Federov, believed in immortalization by scientific means. At the funeral of Lev Karpov in 1921, he said: Shortly after Lenin's death he wrote an article on "The Immortalization of Lenin" and proposed a monument containing Lenin's corpse that would become a center of pilgrimage like Jerusalem or Mecca. Krasin, along with Anatoly Lunacharsky, announced a contest for designs of the permanent monument/mausoleum. Krasin also attempted unsuccessfully to cryogenically preserve Lenin's body.
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Phosphorylation is also a key process of post- transcriptional modification that regulates mRNA expression and cellular localization. Clearly, there are many regulatory mechanisms of activation and repression of hTERT and telomerase activity in the cell, providing methods of immortalization in cancer cells.
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The Biobanking Core Facility has its own dedicated manager. It performs white cell immortalization (from blood) and banking, fibroblast culture and banking, culture and banking of other cell types including non-human cells, genomic DNA preparation from blood, saliva, tissues or cells, and whole-genome amplification (WGA).
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The second novella entitled Perseid follows the middle aged Greek hero Perseus in his struggle to obtain immortality. Told from Perseus' point of view, the first part of the story revolves around the retelling of Perseus' life history while the following part details his rise to, and eventual immortalization as a constellation of stars.
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Houghton Mifflin. . Page 320. Geron published evidence of the role of telomerase in cancer and cell immortalization in collaboration with Woodring Wright and Jerry Shay at the University of Texas Southwestern Medical Center at Dallas. For the company's Scientific and Clinical Advisory Board, he recruited Günter Blobel (winner of the 1999 Nobel Prize in Physiology),Hall, Stephen (2003).
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The focus of science.tv is user-generated content, and much of the content on the site is actually embedded from other video sites, including YouTube. The intended audience is broad, ranging from school students to academics and professional programme-makers.Partial Immortalization, December 31, 2007 Users are able to navigate for content via site-wide search, tags and by preset categories, which include: physics, chemistry and biology.
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Bonfante, 2016, ln. 12 However, Semla continues to appear in artwork in association with an adult Fufluns after her death, indicating either a resurrection or immortalization of his mother.Bonfante and Swaddling, 2006, p. 74 Additionally, Fufluns’s connection to his mother is sometimes cast as romantic, as seen in artwork that shows them in an embrace used elsewhere in Etruscan artwork to indicate erotic entanglement.
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This method has been used to immortalize prostate epithelial and stromal-derived cells, which are typically difficult to culture in vitro. hTERT introduction allows in vitro culture of these cells and available for possible future research. hTERT introduction have an advantage over the use of viral protein for immortalization in that it does not involve the inactivation of tumor suppressor gene, which might lead to cancer formation.
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Báidín Fheilimí on tin whistle Báidín Fheilimí is a traditional Irish song, which originates in the Gaeltacht region in the north-west of County Donegal. It is usually taught to young children. The lyrics are in Irish and is based on the immortalization of a small boat owned by a man called Feilimí (Phelim). It has been covered by artists such as Na Casaidigh, Sinéad O'Connor, Angelo Branduardi, and Emmet Spiceland.
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Director Yaky Yosha's third feature, The Vulture, first screened in 1981, not long before the first war in Lebanon, dealt with the problematic immortalization industry resultant from young war casualties. The film provoked great controversy among the Israeli public, which felt it has crossed a blood-red line. The Israeli censors cut The Vulture, but when selected to represent the country at the Cannes Film Festival, it was screened uncut.
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The lake is from the trailhead, or about two-thirds of the way up to the summit. During summer weekends the Timpanogos Emergency Response Team (TERT) stations volunteers at a camp near Emerald Lake to assist with emergency incidents that frequently occur on the mountain. According to some versions of The Legend of Timpanogos, Emerald Lake is the immortalization of Red Eagle, after he fell to his death from the peak of Mount Timpanogos.
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First out of courtesy, then out of cynicism, Boaz gives them all they're missing: a poem their son allegedly wrote, false tales of heroism and some occasional snapshots. Out of thin air Boaz erects a false monument of a dead hero out of a fairly mediocre child, who didn't get to leave much behind him. Before long, Boas is running a full scale immortalization industry, “manufacturing” for each bereaved family a creative, sensitive son. A soldier and a poet.
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The friendship between the two was fairly close. When Benedict sailed across the English channel to Rome for the last time, he chose only Ceolfrid to join him in his journey. This trip was to be the very trip that would lead to both Abbot's immortalization in the works of Ceolfrid's ward and later contemporary, The Venerable Bede. Ceolfrid also used the trip as an opportunity to explore his role in Biscop's institution, feeling that Rome would be an opportune place to learn his position's responsibilities.
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Despite this strong push for change by the Zhenotdel, the immensely patriarchal society that had existed for hundreds of years prior, would supersede these efforts. The feminist movement was seen by the majority peasant and workforce population as bourgeois, and therefore represented something opposite of the Bolshevik idea. The emphasis on the immediate household as priority was pertinent, especially to the 1930s era of Soviet Russia. Since the Paleolithic era of Russia, there has been a fascination with the immortalization, of the mother figure.
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In most papillomavirus types, the primary function of the E7 protein is to inactivate members of the pRb family of tumor suppressor proteins. Together with E6, E7 serves to prevent cell death (apoptosis) and promote cell cycle progression, thus priming the cell for replication of the viral DNA. E7 also participates in immortalization of infected cells by activating cellular telomerase. Like E6, E7 is the subject of intense research interest and is believed to exert a wide variety of other effects on infected cells.
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Taso's main research interest is nasopharyngeal carcinoma and Epstein-Barr virus, involving cell immortalization and malignant transformation. Emphasis is put on the relationship between latent infection of nasopharyngeal epithelial cells by Epstein-Barr virus and nasopharyngeal carcinoma.Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VM, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW. Epstein-Barr Virus encoded Latent Membrane Protein-1 upregulates glucose transporter-1 transcription via the mTORC1/NF-κB signaling pathways. J Virol. 2017.
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The Epstein–Barr virus nuclear antigen 2 (EBNA-2) is one of the six EBV viral nuclear proteins expressed in latently infected B lymphocytes is a transactivator protein. EBNA2 is involved in the regulation of latent viral transcription and contributes to the immortalization of EBV infected cells. EBNA2 acts as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins, JK recombination signal-binding protein (RBP-JK), and PU.1 as well as working with multiple members of the RNA polymerase II transcription complex.
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Sonnet 55 is interpreted as a poem in part about time and immortalization. The poet claims that his poem will outlast palaces and cities, and keep the young man's good qualities alive until the Last Judgement. The sonnet traces the progression of time, from the physical endeavours built by man (monuments, statues, masonry), as well as the primeval notion of warfare depicted through the image of "Mars his sword" and "war's quick fire", to the concept of the Last Judgment. The young man will survive all of these things through the verses of the speaker.
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The BIR pathway can also help to maintain the length of telomeres (regions of DNA at the end of eukaryotic chromosomes) in the absence of (or in cooperation with) telomerase. Without working copies of the enzyme telomerase, telomeres typically shorten with each cycle of mitosis, which eventually blocks cell division and leads to senescence. In budding yeast cells where telomerase has been inactivated through mutations, two types of "survivor" cells have been observed to avoid senescence longer than expected by elongating their telomeres through BIR pathways. Maintaining telomere length is critical for cell immortalization, a key feature of cancer.
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This simmering acrimony between the union's headquarters and its active members in New Jersey finally erupted in 1928, when the UTW expelled the entire Passaic local for its support of the ongoing Communist-led strike of textile workers in New Bedford, Massachusetts. The Passaic Textile Strike of 1926 is remembered as one of the seminal events in American labor history in the decade of the 1920s. The historical memory of the event has been enhanced due to its immortalization in film. Five of the seven reels of the film The Passaic Textile Strike have survived, with reels 5 and 7 missing.
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Diagnostically, the skin lesions show infiltrating NK cells in the epidermis and subcutaneous tissue with a small fraction of these cells being EBV+ with the virus in its latency II phase. A very high density of EBV+ NK cells in these lesions suggests the disorder has progressed to NK/T cell lymphoma or NK cell leukemia. While the disorder's etiology is unclear, it is thought that the mosquito salivary gland allergenic proteins trigger reactivation of EBV in latently infected NK cells. Upon reactivation, EBV genes such as LMP1 express products that induce immortalization, proliferation, and in some cases malignancy of the EBV reactivated NK cells.
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ENKTCL-NT is thought to arise from the expression of EBV genes in the infected NK or cytotoxic T cells and the ability of these genes to cause the cells they infect to overexpress and acquire mutations in key genes that regulate cell growth, immortalization, invasiveness, and ability to evade normal control mechanisms, particularly immune surveillance. Since these gene-related abnormalities are multiple and vary between patients, it is not clear which contribute to the development and/or progression of ENKTLC-NT. Clinical studies are therefore examining targeted therapy tactics to determine which gene abnormalities contribute to, and which drugs targeting these abnormalities are useful in treating, ENKTCL-NT.
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Demophon would never obtain a life free from death, but Demeter's actions, in fact, prepared and destined him to become immortalized as a recipient of hero cult: while Demophon survives in the Homeric Hymn to Demeter, the scholia attest to other versions in which Demophon does not survive his stay in the fire. The bungled immortalization becomes the cause of his death and funeral games in his honor were established at Eleusis under the guise of a ritual mock-battle, a quasi-athletic event known as the Ballêtus,Bell, John, "Bell's New pantheon; or, Historical Dictionary of the gods, Demi-gods, Heroes and fabulous personages of Antiquity", v.1, 1790. Cf.p.124 entry on Balletus: "A feast observed at Eleusis, in Attica, to the honour of Demophoon, the son of Celeus".
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On December 3, 2004, Wunmi lost her younger brother Jaiyejeje Aboderin, who was only 33 years old. He slumped and died after a game of basketball leaving, behind a wife (actress Stella Damasus) and two daughters, Angelica and Isabel. When he was alive, Jaiye Aboderin supported and encouraged young and upcoming music acts. In 2009, the family launched “Jay Search”, a talent competition in memory of Jaiye Aboderin. The immortalization was embarked on to continue Jaiye’s legacy, because he supported young, up-and-coming artistes to develop their talents, help them grow and assist them in making an impact in the entertainment industry. The first ‘Jay Search’ was in 2009. In December 3, 2009, 23-year-old undergraduate, OluwaSunbo Olundegun also known as ‘Big Ma’ emerged winner of the first edition of Jay’s Search and walked home with a cash prize of N150,000 and a record deal of a single with T.W.O’s ‘Kopykats Entertainment’ record label. Today, she is an on-air personality with a popular lifestyle radio in Nigeria and also runs her PR outfit.
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The 15 tumor types where MORT is frequently silenced are acute myeloid leukemia, bladder urothelial carcinoma, breast invasive carcinoma, colon adenocarcinoma, head and neck squamous-cell carcinoma, kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, liver hepatocellular carcinoma, lung adenocarcinoma, lung squamous cell carcinoma, lymphoid neoplasm diffuse large B-cell lymphoma, pancreatic adenocarcinoma, rectum adenocarcinoma, skin cutaneous melanoma, and Uterine Corpus Endometrial Carcinoma. MORT is silenced in cervical cancer and therefore may serve as an independent prognostic factor with low MORT expression be associated with a decreased overall survival. Since cell immortality is an obligate feature of the cancer cell and MORT was discovered as a target of epigenetic silencing at the boundary where finite lifespan human cells transition from mortal to immortal, MORT’s epigenetic inactivation may create a cellular state permissive to cell immortalization and suggests a possible tumor suppressive mechanism of MORT’s action. If this prediction is true, then epigenetic silencing of MORT should be an early identifiable lesion during human carcinogenesis and predicted to occur in premalignant lesions where cells have acquired pathologic immortality on their route to malignant transformation.
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