Traumatic purpura is a skin condition resulting from trauma which produces ecchymoses of bizarre shapes suggestive of abuse.
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Runner's rump is a cutaneous condition characterized by a small ecchymoses in upper gluteal cleft caused by constant friction with each stride when running.
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Eliciting a full medical history is vital to ensure the low platelet count is not secondary to another disorder. Ensuring that the other blood cell types, such as red blood cells and white blood cells are not also suppressed, is also important. Painless, round, and pinpoint (1 to 3 mm in diameter) petechiae usually appear and fade, and sometimes group to form ecchymoses. Larger than petechiae, ecchymoses are purple, blue, or yellow-green areas of skin that vary in size and shape.
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The most common side effects include lymphadenopathy (swollen lymph nodes), itching, pain, oedema, and bleeding (for example in the form of bruises or ecchymoses). Allergic reactions are seen in less than 1% of patients.
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The word ecchymosis (; plural ecchymoses, ), comes to English from New Latin, based on Greek ἐκχύμωσις ekchymōsis, from ἐκχυμοῦσθαι ekchymousthai "to extravasate blood", from ἐκ- ek- (elided to ἐ- e-) and χυμός chymos "juice". Compare enchyma, "tissue infused with organic juice"; elaboration from chyme, the formative juice of tissues.
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Symptoms include bloody stools, ecchymoses, blood leakage from venipuncture sites, mucosal & visceral hemorrhaging, and possibly hematemesis. # Late Organ Phase: Day 13 up to Day 21+. Symptoms bifurcate into two constellations for survivors & fatal cases. Survivors will enter a convalescence phase, experiencing myalgia, fibromyalgia, hepatitis, asthenia, ocular symptoms, & psychosis.
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Petechiae and ecchymoses may be seen on mucous membranes. Bleeding from the lungs may also be seen in dogs. In chronic presentations, the affected dog may have no symptoms. In animals that have died of leptospirosis, their kidneys may be swollen with grey and white spots, mottling, or scarring.
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Epistaxis, petechiae and ecchymoses are common symptoms, as are subconjunctival bleeding and menorrhagia. On average, bleeding will persist for approximately eight days, and may reoccur. Approximately 80 percent of cases will exhibit chronic thrombocytopenia. Periodic episodes of acute hemorrhage are also possible and may be severe, possibly leading to shock and death.
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This may cause vomiting blood, coughing up of blood, or blood in stool. Bleeding into the skin may create petechiae, purpura, ecchymoses or haematomas (especially around needle injection sites). Bleeding into the whites of the eyes may also occur. Heavy bleeding is uncommon; if it occurs, it is usually in the gastrointestinal tract.
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Clinical signs only occur in chicks less than three weeks of age. During outbreaks of CAV, up to 10% of chicks can die. Signs include a pale comb, wattle, eyelids, legs and carcass, anorexia, weakness, stunting, unthriftiness, weight loss, cyanosis, petechiation and ecchymoses, lethargy, and sudden death. Neurological signs include dullness, depression and paresis.
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Classical-like EDS is characterized by skin hyperextensibility with velvety skin texture and absence of atrophic scarring, generalized joint hypermobility with or without recurrent dislocations (most often shoulder and ankle), and easily bruised skin or spontaneous ecchymoses (discolorations of the skin resulting from bleeding underneath). It can be caused by variations in the TNXB gene.
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They can occur anywhere on the body. A person with this disease may also complain of malaise, fatigue, and general weakness (with or without accompanying blood loss). Acquired thrombocytopenia may be associated with the use of certain drugs. Inspection typically reveals evidence of bleeding (petechiae or ecchymoses), along with slow, continuous bleeding from any injuries or wounds.
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Adverse events are not extensively reported in the literature. They are usually mild and self-limiting; however, it may partly account for lack of patient compliance with penile traction therapy (PTT). The most commonly reported symptoms with PTT include pain, erythema, ecchymoses and pruritus. There has also been a case report of pubic bone edema associated with vigorous usage.
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Their liver may be enlarged with areas of cell death. Petechiae and ecchymoses may be found in various organs. Inflammation of the blood vessels, inflammation of the heart, meningeal layers covering the brain and spinal cord, and uveitis are also possible. Equine recurrent uveitis (ERU) is the most common disease associated with Leptospira infection in horses in North America and may lead to blindness.
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Solar purpura (also known as "Actinic purpura," and "Senile purpura") is a skin condition characterized by large, sharply outlined, 1- to 5-cm, dark purplish-red ecchymoses appearing on the dorsa of the forearms and less often the hands. The condition is most common in elderly people of European descent. It is caused by sun-induced damage to the connective tissue of the skin.Scheinfeld NS (2009).
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Recipients in this category include those undergoing chemotherapy, those with myelophthisic anemia, AIDS, or with aplastic anemia. If indicated, transfusions (one thrombapheresis concentrate) should be given until recovery of platelet function, generally approximately twice weekly. Surgical bleeding due solely to thrombocytopenia occurs when platelets < 50,000/µL while spontaneous bleeding occurs when platelets < 10,000/µL. Thrombocytopenic patients can develop "dry" bleeding, that is, petechiae and ecchymoses only.
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According to Hartung "If this were the case of St. Francis, he would have been afflicted by ecchymoses, an exceedingly large purpura. The purple spots of blood may have been punctured while in the wilderness and there appear as an open wound like that of Christ." A later medical hypothesis was proposed in 1987 to explain the wounds, it claimed that St. Francis may have contracted leprosy.Schazlein, Joanne; Sulmasy, Daniel P. (1987).
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Horses that develop purpura hemorrhagica usually have a recent history of strangles (infection with Streptococcus equi subsp. equi) or vaccination (intramuscular or intranasal) for strangles. It is thought to be caused by an auto-immune reaction where antibodies against the S. equi M- or R-protein cross-react with proteins on endothelial cells. This results in vasculitis, leading to subsequent severe peripheral edema in the legs and ventral abdomen, as well as petechiation or ecchymoses over the mucous membranes.
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While rare, skin lesions may occur in the acquired form of the disease, including roseola and erythema multiforme-like eruptions, prurigo-like nodules, urticaria, and maculopapular lesions. Newborns may have punctate macules, ecchymoses, or "blueberry muffin" lesions. Diagnosis of cutaneous toxoplasmosis is based on the tachyzoite form of T. gondii being found in the epidermis. It is found in all levels of the epidermis, is about 6 by 2 μm and bow-shaped, with the nucleus being one-third of its size.
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The skin can show the effects of vascular damage often coupled with depletion of coagulation factors in the form of petechiae, purpura and ecchymoses. The limbs can also be affected, sometimes with devastating consequences such as the development of gangrene, requiring subsequent amputation. Loss of function of the adrenal glands can cause adrenal insufficiency and additional hemorrhage into the adrenals causes Waterhouse-Friderichsen syndrome, both of which can be life-threatening. It has also been reported that gonococcal LOS can cause damage to human fallopian tubes.
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The most detailed study on the frequency, onset, and duration of MVD clinical signs and symptoms was performed during the 1998–2000 mixed MARV/RAVV disease outbreak. A maculopapular rash, petechiae, purpura, ecchymoses, and hematomas (especially around needle injection sites) are typical hemorrhagic manifestations. However, contrary to popular belief, hemorrhage does not lead to hypovolemia and is not the cause of death (total blood loss is minimal except during labor). Instead, death occurs due to multiple organ dysfunction syndrome (MODS) due to fluid redistribution, hypotension, disseminated intravascular coagulation, and focal tissue necroses.
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Painful bruising syndrome (also known as "autoerythrocyte sensitization", "Gardner–Diamond syndrome", and "psychogenic purpura") is an idiopathic trauma-induced condition seen in young to middle-aged women who sometimes manifest personality disorders. It is characterized by a distinctive localized purpuric reaction occurring primarily on the legs, face and trunk, with recurring painful ecchymoses variably accompanied by syncope, nausea, vomiting, gastrointestinal and intracranial bleeding. Patients with this condition can suffer frequent painful bruising around joints and muscles. Because of the rarity of the disorder, there are few methods of support in place for patients.
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Over his 23-year career, Tardieu participated as a forensic expert in 5,238 cases, including many famous and notorious historical crimes. Using his cases as a statistical base, Tardieu wrote over a dozen volumes of forensic analysis, covering such diverse areas as abortion, drowning, hanging, insanity, homosexuality, poisoning, suffocation, syphilis, and tattoos. In recognition of his first clinical descriptions of battered children, battered child syndrome is also known as Tardieu's syndrome. Tardieu's ecchymoses, subpleural spots of ecchymosis that follow the death of a newborn child by strangulation or suffocation, were first described by Tardieu in 1859, and were so named in his honor.
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Patients with bleeding disorders show a higher incidence of periodontal disease as well as dental caries, concerning the fear of bleeding which leads to a lack of oral hygiene and oral health care. The most prominent oral manifestation of a mild haemophilia B would be gingival bleeding during exfoliation of primary dentition, or prolonged bleeding after an invasive procedure/tooth extraction; In severe haemophilia, there may be spontaneous bleeding from the oral tissues (eg. soft palate, tongue, buccal mucosa), lips and gingiva, with ecchymoses. In rare cases, hemarthrosis (bleeding into joint space) of the temporomandibular joint (TMJ) may be observed.
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Mass casualties occurred in the Soviet Union in the 1930s and 1940s when Fusarium-contaminated wheat flour was baked into bread, causing alimentary toxic aleukia with a 60% mortality rate. Symptoms began with abdominal pain, diarrhea, vomiting, and prostration, and within days, fever, chills, myalgias and bone marrow depression with granulocytopenia and secondary sepsis occurred. Further symptoms included pharyngeal or laryngeal ulceration and diffuse bleeding into the skin (petechiae and ecchymoses), melena, bloody diarrhea, hematuria, hematemesis, epistaxis, vaginal bleeding, pancytopenia and gastrointestinal ulceration. Fusarium sporotrichoides contamination was found in affected grain in 1932, spurring research for medical purposes and for use in biological warfare.
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Close-up view of an actinic keratosis lesion Multiple lesions of actinic keratosis on the scalp. Actinic keratoses (AKs) most commonly present as a white, scaly plaque of variable thickness with surrounding redness; they are most notable for having a sandpaper-like texture when felt with a gloved hand. Skin nearby the lesion often shows evidence of solar damage characterized by notable pigmentary alterations, being yellow or pale in color with areas of hyperpigmentation; deep wrinkles, coarse texture, purpura and ecchymoses, dry skin, and scattered telangiectasias are also characteristic. Photoaging leads to an accumulation of oncogenic changes, resulting in a proliferation of mutated keratinocytes that can manifest as AKs or other neoplastic growths.
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Although patients at high risk of bleeding were excluded from the phase III clinical study (PROWESS), 25% of patients treated with drotrecogin and 18% of those receiving placebo experienced at least one bleeding event (principally ecchymoses or GI bleeding) during the 28-day study period. During treatment serious bleeding events (e.g., intracranial hemorrhage, any life-threatening bleeding event, any bleeding event requiring administration of at least 3 units of packed red blood cells daily for 2 consecutive days) occurred in 2.4% of patients treated with drotrecogin and in 1% of those receiving placebo. No significant differences between geriatric patients and younger patients regarding bleeding events in the drotrecogin group have been found.
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Spontaneous and excessive bleeding can occur because of platelet disorders. This bleeding can be caused by deficient numbers of platelets, dysfunctional platelets, or very excessive numbers of platelets: over 1.0 million/microliter. (The excessive numbers create a relative von Willebrand factor deficiency due to sequestration.) One can get a clue as to whether bleeding is due to a platelet disorder or a coagulation factor disorder by the characteristics and location of the bleeding. All of the following suggest platelet bleeding, not coagulation bleeding: the bleeding from a skin cut such as a razor nick is prompt and excessive, but can be controlled by pressure; spontaneous bleeding into the skin which causes a purplish stain named by its size: petechiae, purpura, ecchymoses; bleeding into mucous membranes causing bleeding gums, nose bleed, and gastrointestinal bleeding; menorrhagia; and intraretinal and intracranial bleeding.
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This Second issue is more experimental with Marcel Duchamp, Nicolas Calas, Bruce Conner, Marcia Herscovitz, Alain Jacquet, Ray Johnson, Lee Lozano, Meret Oppenheim, Bernard Pfreim, George Reavevy, Clovis Trouille. The cover, designed by Marcel Duchamp, is a white folder with a playable record album attached to the front. Printed on the record itself is ESQUIVONS LES ECCHYMOSES DES ESQUIMAUX AUX MOTS EXQUIS, which roughly translates to “dodge the Eskimo bruises with exquisite words,” but functions as a sort of French tongue twister. Duchamp seems to be playfully addressing the restrictions inherent in more traditional portfolio design in order to redefine this practice. The record has aesthetic appeal, but it similarly has far greater use value than the first issue’s front cover, which was a reproduction of a painting. Another particularly provocative work in Shit Must Stop N°2 is Bruce Connor’s Legal Tender. Connor mimics the design of American currency with his stack of eighteen “dollar bills,” which seem more reminiscent of Monopoly money than American legal tender. This element allows for the whole issue to feel like a game, as if you could trade Connor’s money for something more valuable.
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