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341 Sentences With "contraindications"

How to use contraindications in a sentence? Find typical usage patterns (collocations)/phrases/context for "contraindications" and check conjugation/comparative form for "contraindications". Mastering all the usages of "contraindications" from sentence examples published by news publications.

Perhaps there were no contraindications between it and vodka martinis?
"Medical contraindications to breastfeeding are rare," the policy's abstract states.
Other contraindications for medication abortion include having blood disorders or taking blood thinners.
We tried one another's benzos and antivirals, Restoril, Avodart, Yaz, and Dexedrine, looking for contraindications.
The annual flu vaccine is now available for anyone over six months old without contraindications.
In government, immediate needs and instantaneous gratification by way of spreadsheets seldom fully consider the contraindications of policy decisions.
Automated checklists used by online vendors greatly reduce the chances of prescribing the pills in case of contraindications, Mehrotra said.
Check with your doctor to understand the source of your back pain and any associated contraindications before beginning this or any exercise program.
"There can be poor understanding of the side effects profile of the meds, poor dosing, failure to understand any contraindications and dependency from excess usage," Barkley said.
Safely prescribing medication—including screening patients for any contraindications, counseling them about their options, and looking out for medication interactions—are typical responsibilities for primary care physicians.
Australia's Department of Social Services here indicates that there are still a number of reasons for a child to be exempted from vaccination, including medical contraindications or natural immunity.
If you are still considering an aspirin preventive for a flight, discuss this with your doctor first to be sure there are no contraindications based on your personal medical history.
"If no contraindications, hormone therapy given until the average age of menopause will decrease those health risks to those of women going through menopause at a normal age," Pinkerton said.
"Before using a new essential oil, become familiar with its properties, methods of application, toxicity, precautions, and contraindications," Stephanie Tourles, author of Stephanie Tourles's Essential Oils: A Beginner's Guide, previously told Refinery29.
Among the few medical contraindications to breast-feeding are infections in the mother – H.I.V., untreated tuberculosis, chickenpox or a herpes lesion on the nipple – and mothers being treated with cell-killing cancer drugs.
Young people also consider issues like protection against sexually transmitted infections, medical contraindications, ability to easily discontinue use, and our country's history of forced sterilization and testing of I.U.D.s on communities of color.
They can advise patients about certain contraindications: Estrogen-based birth control, for instance, poses an elevated risk of blood clots, particularly to people who are older, obese, heavy smokers, or otherwise predisposed to them.
Drug manufacturers will be required to update their package inserts to reflect the new contraindications, the strongest kind of warning, to alert doctors and parents that children can have trouble breathing or die after taking these drugs.
While certain conditions are widely agreed to be contraindications for home birth—like having a placenta that covers the cervix, for example—many of the worst-case scenarios are difficult to predict prior to the onset of labor.
In girls who can't take hormonal contraceptives because of medical contraindications, or whose families don't want them to, Provera, another form of female hormone that helps regulate menstruation, is sometimes used to induce what is called a "withdrawal bleed" if they go for more than three months without a period.
Contraindications are circumstances that indicate the treatment or operation should not be provided due to potential harm. Contraindications for cranioplasty include the presence of bacterial infection, brain swelling, and hydrocephalus. Cranioplasty is withheld until all contraindications are cleared.
While no firmly established absolute contraindications exist for lymphatic techniques, the following cases are examples of relative contraindications: bone fractures, bacterial infections with fever, abscesses, and cancer.
Contraindications to chest tube placement include refractory coagulopathy and presence of a diaphragmatic hernia, as well as hepatic hydrothorax. Additional contraindications include scarring in the pleural space (adhesions).
There are no specific contraindications for sofosbuvir when used alone. However, when used in combination with ribavirin or peginterferon alfa/ribavirin, or others, the contraindications applicable to these agents are applied.
There are no known absolute contraindications for the use of pralidoxime. Relative contraindications include known hypersensitivity to the drug and other situations in which the risk of its use clearly outweighs possible benefit.
Risks and contraindications are the same of any MR exam.
Oral ketoconazole has various contraindications, such as concomitant use with certain other drugs due to known drug interactions. Other contraindications of oral ketoconazole include liver disease, adrenal insufficiency, and known hypersensitivity to oral ketoconazole.
These would be same as the contraindications for any other surgery.
Adverse effects, contraindications and interactions are similar to other beta blockers.
General contraindications of estrogens include breast cancer, endometrial cancer, and others.
No clinically relevant contraindications or interactions with other drugs are known.
All treatments need a thorough medical history, diagnosis and plan of management. Chiropractors must rule out contraindications to any treatments, including adverse events. Relative contraindications, such as osteoporosis are conditions where increased risk is acceptable in some situations and where mobilization and soft-tissue techniques may be treatments of choice. Most contraindications apply to the manipulation of the affected region.
See leflunomide for information on pharmacokinetics, side effects, contraindications and other data.
There are no contraindications to the use of benzydamine except for known hypersensitivity.
Contraindications of apalutamide include pregnancy and a history of or susceptibility to seizures.
There are no absolute contraindications to thoracostomy. There are relative contraindications (such as coagulopathies); however, in an emergency setting these are outweighed by the necessity to re- inflate a collapsed lung by draining fluid/air from the space around the lung.
Contraindications and risk include cerebral aneurysms, heart attack, emphysema, multiple sclerosis, and muscular dystrophy.
Contraindications of CEEs include breast cancer and a history of venous thromboembolism, among others.
Bosutinib has two known absolute contraindications, which are: known hypersensitivity to bosutinib and liver impairment.
Side effects, interactions, and contraindications have only been evaluated in the drug combination lopinavir/ritonavir.
Contraindications of progestogens may include breast cancer and a history of venous thromboembolism among others.
Contraindications are severe obstructive cardiomyopathy, hypovolemia, tachycardia, and ventricular aneurysm. Breast feeding is prohibited during treatment.
Chiropractic adjustment on children The World Health Organization found chiropractic care in general is safe when employed skillfully and appropriately. There is not sufficient data to establish the safety of chiropractic manipulations. Manipulation is regarded as relatively safe but complications can arise, and it has known adverse effects, risks and contraindications. Absolute contraindications to spinal manipulative therapy are conditions that should not be manipulated; these contraindications include rheumatoid arthritis and conditions known to result in unstable joints.
Contraindications for the procedure are based on the patient’s physiologic condition of the CBD and the duodenum.
Interactions, adverse effects and contraindications are described in more detail in the articles about pseudoephedrine and loratadine.
Contraindications to receiving amifostine include hypersensitivity to amifostine and aminothiol compounds like WR-1065. Ethyol contains mannitol.
Contraindications to facelift surgery include severe concomitant medical problems, both physical and psychological. While not absolute contraindications, the risk of postoperative complications is increased in cigarette smokers and patients with hypertension and diabetes. These strong relative contraindications consist primarily of diseases predisposing to poor wound healing. Patients are typically asked to abstain from taking aspirin or other blood thinners for at least one week prior to surgery. Patients motivations and expectations are an important factor in order to determine the patient’s medical status.
Contraindications to the ultrasound contrast include allergy, heart failure, acute coronary syndrome, endocarditis, ventricular arrhythmia, and unstable respiration.
Contraindications are peptic ulcers, acute bleeding, recent heart attack, acute decompensated heart failure, and severe chronic kidney disease.
Advancements have been made to improve the design of the implants. Also, choosing the best-suited people was emphasized to ensure that surgeons followed the indications and contraindications for partial replacement. Proper selection, following the indications/contraindications, and performing the surgery well are key factors for the success of UKA.
Conditions that are absolute contraindications despite bladder adequacy include duplication of the penis or scrotum and significant bilateral hydronephrosis.
Contraindications of OHPC include previous or current thrombosis or thromboembolic disease, known or suspected breast cancer, past or present history of other hormone-sensitive cancer, undiagnosed abnormal vaginal bleeding unrelated to pregnancy, cholestatic jaundice of pregnancy, liver tumors or active liver disease, and uncontrolled hypertension. A few relative contraindications also exist for OHPC.
Additional contraindications for the children's formulation are hereditary fructose intolerance, glucose-galactose malabsorption and saccharase deficiency, as it contains sugar.
Eylea is contraindicated in patients with infections or active inflammations of or near the eye, while Zaltrap has no contraindications.
Similarly, a person with hemochromatosis should not be administered iron preparations. Relative contraindications are contraindications for circumstances in which the patient is at higher risk of complications from treatment, but these risks may be outweighed by other considerations or mitigated by other measures. For example, a pregnant woman should normally avoid getting X-rays, but the risk may be outweighed by the benefit of diagnosing (and then treating) a serious condition such as tuberculosis. Relative contraindications may also be referred to as cautions, such as in the British National Formulary.
A DT vaccine is available for children under the ages of seven who have contraindications or precautions to pertussis-containing vaccines.
General contraindications of estrogens include breast cancer, endometrial cancer, and others. In animals, estriol is contraindicated during pregnancy and in ferrets.
Contraindications for riluzole include: known prior hypersensitivity to riluzole or any of the excipients inside the preparations, liver disease, pregnancy or lactation.
The PDR Electronic Library provides access to FDA approved drug information to include drug interactions, side effects, recommended dosages, contraindications, and more.
When medical contraindications to beta-blockers exist, such as significant reactive airway disease, then treatment with prophylactic endoscopic variceal ligation is often performed.
A few contraindications should be taken into account for atomoxetine. The first one is hypersensitivity but patients known to be hypersensitive to atomoxetine or other constituents of the product should avoid using it. MAO inhibitor (MAOI) should also be taken into account for contraindications. Atomoxetine should not be taken within 2 weeks after discontinuing an MAOI or completely avoid taking MAOI.
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or significant self-neglect or other symptoms.
HBOT is considered very safe, with few contraindications, although its cost and availability make it less widely used than most other forms of treatment.
Contraindications of estrogens include coagulation problems, cardiovascular diseases, liver disease, and certain hormone-sensitive cancers such as breast cancer and endometrial cancer, among others.
Contraindications of estrogens include coagulation problems, cardiovascular diseases, liver disease, and certain hormone-sensitive cancers such as breast cancer and endometrial cancer, among others.
Contraindications of estrogens include coagulation problems, cardiovascular diseases, liver disease, and certain hormone- sensitive cancers such as breast cancer and endometrial cancer, among others.
Contraindications of estrogens include coagulation problems, cardiovascular diseases, liver disease, and certain hormone-sensitive cancers such as breast cancer and endometrial cancer, among others.
Contraindications of estrogens include coagulation problems, cardiovascular diseases, liver disease, and certain hormone- sensitive cancers such as breast cancer and endometrial cancer, among others.
Absolute contraindications to taking perindopril/indapamide include a known allergy to perindopril, indapamide, or sulfonamides; history of Quincke's edema linked to previous ACE inhibitor therapy; end-stage kidney disease; serious liver disease; high levels of potassium in the blood; pregnancy; and lactation. Relative contraindications to using this medication include combination therapy with lithium, potassium salts, potassium-sparing diuretics, and certain medicines which can cause abnormal heart rhythms.
Most contraindications are relative, balancing the risks of the procedure versus the potential benefits. The relative contraindications are: # Conditions incompatible with normal life if the person recovers # Preexisting conditions that affect the quality of life (CNS status, end-stage malignancy, risk of systemic bleeding with anticoagulation) # Age and size # Futility: those who are too sick, have been on conventional therapy too long, or have a fatal diagnosis.
Small to medium-sized breasts. Primary bilateral reconstruction after skin sparing mastectomy. ;Contraindications Large sized breasts. Patients with inadequate thigh tissue or after previous thigh lift.
Intact D&E; is more feasible among women with higher parity, at higher gestational ages, and when cervical dilation is greater. There are no absolute contraindications.
It is also used in patients with contraindications for surgery. It has also been used as a reversible test to confirm whether a surgical intervention would help.
Contraindications for macrogol taken orally as a laxative are intestinal perforation, bowel obstruction, ileus, inflammatory bowel diseases, and toxic megacolon. The doses of macrogol as an excipient are too low to have relevant contraindications. Allergy to macrogol is rare, and usually appears as an allergy to an increasing number of seemingly unrelated products, including cosmetics, drugs that use it as an excipient, and peri-procedural substances such as ultrasound gel.
Contraindications for treatment with olmesartan include biliary obstruction. Another major contraindication is pregnancy; reports in the scientific literature reveal fetal malformations for pregnant women taking sartan-derived drugs.
In life saving situations with the consent of the surgeon, autotransfusion can be utilized in the presence of the previous stated contraindications i.e. sepsis, bowel contamination and malignancy.
Other contraindications for partial cystectomy include severely diminished bladder capacity or cancer in very close proximity to the bladder trigone, where the urethra and ureters connect to the bladder.
Contraindications of anastrozole include hypersensitivity to anastrozole or any other component of anastrozole formulations, pregnancy, and breastfeeding. Hypersensitivity reactions to anastrozole including anaphylaxis, angioedema, and urticaria have been observed.
The few contraindications to surgery include inoperable tumor, massive obesity, a particularly high-risk operation, or a desire to preserve fertility. These contraindications happen in about 5–10% of cases. Women who wish to preserve their fertility and have low-grade stage I cancer can be treated with progestins, with or without concurrent tamoxifen therapy. This therapy can be continued until the cancer does not respond to treatment or until childbearing is done.
A person with any infection should not use biologics. Other contraindications for biologics include cancer, certain neurologic disorders, being pregnant or breastfeeding, history of heart failure, or history of tuberculosis.
Acute intermittent porphyria, hypersensitivity to any barbiturate, prior dependence on barbiturates, severe respiratory insufficiency (as with chronic obstructive pulmonary disease), severe liver failure, pregnancy, and breastfeeding are contraindications for phenobarbital use.
Other contraindications are severe liver disease and concomitant use of isotretinoin or other retinoids, as both tetracyclines and retinoids can cause intracranial hypertension (increased pressure around the brain) in rare cases.
Field tests to date have not uncovered specific contraindications of ambroxol; however, caution is suggested for patients with gastric ulceration, and usage during the first trimester of pregnancy is not recommended.
Darolutamide has no contraindications in men. However, the medication may have teratogenic effects in male fetuses due to its antiandrogenic effects and hence should not be used by women who are pregnant.
In 2012, the American College of Chest Physicians recommended IVC filters for those with contraindications to anticoagulation who either have acute PE or acute proximal (above the knee) deep vein thrombosis (DVT).
Contraindications for parenteral or oral administration include benign prostatic hyperplasia, peptic ulcer, pyloric and duodenal stenosis, uncontrolled glaucoma, pregnancy and breast-feeding. It is not intended for the management of acute bronchospasm.
There are several contraindications for air polishing. These include: sodium restricted diet, hypertension, respiratory illnesses, infectious diseases, chronic kidney disease, Addison's or Cushing's disease, and some medications (mineralocorticoid steroids, anti-diuretics, potassium supplements).
The study also concluded that it would be impossible to eliminate absolutely all minor contraindications of Scuba diving, as this would result in overwhelming bureaucracy and would bring all diving to a halt.
The decision to use postural drainage therapy requires assessment of potential benefits versus potential risks. Therapy should be provided for no longer than necessary to obtain the desired therapeutic results. Some of the contraindications include an increased intracranial pressure (>20 mmHg), any spinal injury acute or otherwise, active hemoptysis, pulmonary embolism, pulmonary edema with congestive heart failure and an open or healing wound in the area where chest physiotherapy is otherwise indicated. Medication contraindications vary depending on the medication being delivered.
Relative contraindications are conditions where increased risk is acceptable in some situations and where low-force and soft- tissue techniques are treatments of choice; these contraindications include osteoporosis. Although most contraindications apply only to manipulation of the affected region, some neurological signs indicate referral to emergency medical services; these include sudden and severe headache or neck pain unlike that previously experienced. • Indirect risks of chiropractic involve delayed or missed diagnoses through consulting a chiropractor. Spinal manipulation is associated with frequent, mild and temporary adverse effects, including new or worsening pain or stiffness in the affected region. They have been estimated to occur in 33% to 61% of patients, and frequently occur within an hour of treatment and disappear within 24 to 48 hours; adverse reactions appear to be more common following manipulation than mobilization.
It was outlawed in many countries due to its adverse effects on poor metabolisers (PM). The product has been reintroduced for patients who have contraindications, or have not responded to other treatments for angina.
Tamoxifen has a number of contraindications, including known hypersensitivity to tamoxifen or other ingredients, individuals taking concomitant coumarin-type anticoagulant therapy, and women with a history of venous thromboembolism (deep vein thrombosis or pulmonary embolism).
Additionally, patients who have an inadequate predicted FLR post PVE should not be considered. Other contraindications include any conditions that make a patient unfit for surgery or intervention (poor cardiopulmonary status, sepsis, kidney failure, etc).
Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. MedicineNet: Cevimeline. Accessed 10/12/2007 Contraindications include asthma and angle closure glaucoma.
In some countries these may be considered absolute contraindications, while in others the severity may be taken into consideration. Asthmatics with a mild and well controlled condition may be permitted to dive under restricted circumstances.
Contraindications include an allergy to the medication, pregnancy, prior liver problems, abnormal vaginal bleeding of unclear cause, ovarian cysts other than those due to polycystic ovarian syndrome, unmanaged adrenal or thyroid problems, and pituitary tumors.
Absolute contraindications of testosterone include prostate cancer, elevated hematocrit (>54%), uncontrolled congestive heart failure, various other cardiovascular diseases, and uncontrolled obstructive sleep apnea. Breast cancer is said by some sources to be an absolute contraindication of testosterone therapy, but androgens including testosterone have also actually been used to treat breast cancer. Relative contraindications of testosterone include elevated prostate-specific antigen (PSA) in men with a high risk of prostate cancer due to ethnicity or family history, severe lower urinary tract symptoms, and elevated hematocrit (>50%).
The main contraindication for inhaled ipratropium is hypersensitivity to atropine and related substances. For oral administration, contraindications are similar to other anticholinergics; they include narrow angle glaucoma and obstructions in the gastrointestinal tract and urinary system.
Contraindications are hypersensitivity against ACE inhibitors, especially if it has resulted in angioedema; idiopathic or hereditary angioedema; kidney failure; the second and third trimesters in pregnancy; and combination with the drug aliskiren in people with diabetes.
Contraindications to ticagrelor are active bleeding, increased risk of bradycardia, concomitant therapy of ticagrelor and strong cytochrome P-450 3A (CYP3A4) inhibitors and moderate or severe hepatic impairment due to the risk of increased exposure to ticagrelor.
There are no contraindications for the use of valbenazine according to the prescribing information. Valbenazine has not been effectively studied in pregnancy, and it is recommended that women who are pregnant or breastfeeding avoid use of valbenazine.
When considering the use of a local anaesthesia there are many factors which should be considered. In terms of contraindications associated with LA there are “absolute” and “relative” contraindications. When something is said to have an “absolute” contraindication this underlines that under no circumstance would that LA be selected to administer to that specific patient as it poses a potential life-threatening risk e.g. allergy. When the LA has a “relative” contraindication the administration of the LA is not preferable and should be avoided, but does not pose a life-threatening risk.
An uncooperative patient or a coagulation disorder that cannot be corrected are relative contraindications. Routine measurement of coagulation profiles is generally not indicated, however; when performed by an experienced operator "hemorrhagic complications are infrequent after ultrasound-guided thoracentesis, and attempting to correct an abnormal INR or platelet level before the procedure is unlikely to confer any benefit." Relative contraindications include cases in which the site of insertion has known bullous disease (e.g. emphysema), use of positive end-expiratory pressure (PEEP, see mechanical ventilation) and only one functioning lung (due to diminished reserve).
A study in 2011 came to the result that categories most frequently absent in Wikipedia's drug articles are those of drug interactions and medication use in breastfeeding. Other categories with incomplete coverage were descriptions of off-label indications, contraindications and precautions, adverse drug events and dosing. Information most frequently deviating from other sources used in the study were that of contraindications and precautions, drug absorption and adverse drug events. A 2012 study reported that Wikipedia articles about pediatric otolaryngology contained twice as many errors and omissions as the medical database eMedicine.
It is a good alternative to the DIEAP flap. ;Disadvantages The same as for the DIEAP flap. ;Indications When a DIEAP flap is not possible because of unsuitable or insufficient perforators. ;Contraindications Analogue to the DIEAP flap technique.
Asanas have, or are claimed to have, multiple effects on the body, both beneficial and harmful. These include the conscious usage of groups of muscles, effects on health, and possible injury especially in the presence of known contraindications.
Most contraindications are relative, such as nausea, hemodynamic instability, tracheal fistula, singulation and hemoptysis. Untreated tension pneumothorax is an absolute contraindication. IMPLEMENTATION When treating atelectasis - # Therapy should be volume-oriented 2\. Tidal volumes(VT) must be measured 3\.
Racecadotril has no contraindications apart from known hypersensitivity to the substance.Mediq.ch: racecadotril. Accessed 2019-12-30. There is insufficient data for the therapy of chronic diarrhea, for patients with renal or hepatic failure, and for children under three months.
In the US the only contraindication for tetracosactide for diagnostic use is hypersensitivity to ADCH but in the UK, regulators placed contraindications for hypersensitivity to ADCH and additionally, for people with allergic disorders including asthma, acute psychosis, infectious diseases, peptic ulcer, refractory heart failure, Cushing's syndrome, treatment of primary adrenocortical insufficiency and adrenocongenital syndrome. The same contraindications that were applied in the UK for diagnostic use of tetracosactide, apply for therapeutic use of both tetracosactide and corticotropin in the US and UK. In addition, the US label for corticotropin for therapeutic uses includes contraindications for people who have recently had surgery, and people with scleroderma, osteoporosis, uncontrolled hypertension, or sensitivity to proteins of porcine origin; in addition the infection diseases systemic fungal infection, ocular herpes simplex, and infants who have congenital infections are specified. The label also notes that people taking corticotropin for immunosuppression should not be given live vaccines.
No contraindications are known for this examination. Ultrasonography does not involve the use of ionizing radiation, and the procedure is harmless and can be safely used on anybody of any age. A World Health Organization report published in 1998 supports this.
The DSM-IV itself states that in rare instances, gender dysphoria may co-exist with schizophrenia, and that psychiatric disorders are not generally considered contraindications to sex reassignment therapy unless they are the primary cause of the patient's gender dysphoria.
Long abdominal donor site scar. ;Indications The same as for DIEAP flap, and the presence of a superficial inferior epigastric artery with an adequate diameter. ;Contraindications The same as for DIEAP flap, and an absent or inadequate superficial inferior epigastric artery.
Contraindications include: atherosclerosis, Buerger's syndrome, coronary artery disease, hepatic disease, pregnancy, pruritus, Raynaud's syndrome, and renal disease. It's also contraindicated if patient is taking macrolide antibiotics (e.g., erythromycin), certain HIV protease inhibitors (e.g., ritonavir, nelfinavir, indinavir), certain azole antifungals (e.g.
Anticholinergic agents reduce the action of itopride. It is worth noting that itopride is a relatively new drug and that it is, therefore, possible that other drugs may interact with itopride, rendering contraindications or side effects that are not currently known.
Contraindications are basically the same as with other NSAIDs: hypersensitivity reactions to NSAIDs in the past (typically asthma or skin reactions), gastrointestinal or cerebral bleeding, peptic ulcer, haematopoietic disorders (anaemia, leukopenia), and during the third trimester of pregnancy. on Emflex.
The drug label advises that hydroxychloroquine should not be prescribed to individuals with known hypersensitivity to 4-aminoquinoline compounds. There are several other contraindications, and caution is required if the person considered for treatment has certain heart conditions, diabetes, or psoriasis.
AG should not be used in people with known hypersensitivity to AG. It should not be used in women who are pregnant or breastfeeding. Other potential contraindications include chicken pox, shingles (herpes zoster), infection, kidney disease, liver disease, and hypothyroidism.
In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment. Absolute contraindications are contraindications for which there are no reasonable circumstances for undertaking a course of action. For example, children and teenagers with viral infections should not be given aspirin because of the risk of Reye's syndrome, and a person with an anaphylactic food allergy should never eat the food to which they are allergic.
Contraindications include small and medium breeds of dogs that are less than 8 months old; large breeds less than 12 months old; giant breeds less than 18 months old; those with suspected CNS disorders; and hypersensitivity to difloxacin or any other fluoroquinolone.
However, lisinopril is dosed once a day, whereas captopril may be dosed 2-3 times a day. Assuming that there are no contraindications or potential for drug interactions, using lisinopril instead of captopril may be an appropriate way to limit pill burden.
There are certain criteria for an amniotomy to be performed: 1\. The mother should have no contraindications for vaginal delivery. 2\. The mother should be in labor or have an indication for delivery. 3\. The head should be engaged (0 station or more).
Artesunate is typically a well tolerated medicine. Known contraindications include a previous severe allergic reaction to artesunate. Drugs that should be avoided while on artesunate are the drugs that inhibit the liver enzyme CYP2A6. These drugs include amiodarone, desipramine, isoniazid, ketoconazole, letrozole, methoxsalen, tranylcypromine.
Contraindications often depend on the substance in question. Documented hypersensitivity to any ingredients and anemias without proper work-up (i.e., documentation of iron deficiency) is true of all preparations. Some can be used in iron deficiency, others require iron deficiency anaemia to be present.
Contraindications are hypersensitivity to phenazone, propyphenazone, aminophenazone, metamizol, phenylbutazone, paracetamol, acetylsalicylic acid, or caffeine; bone marrow deficiencies; glucose-6-phosphate dehydrogenase deficiency; acute hepatic porphyria; alcoholism; gastrointestinal ulcers or bleeding; pregnancy and lactation; infants and children under 6 to 12 years (varying by country).
A therapy or medical treatment (often abbreviated tx, Tx, or Tx) is the attempted remediation of a health problem, usually following a diagnosis. As a rule, each therapy has indications and contraindications. There are many different types of therapy. Not all therapies are effective.
In 1962, the United States Congress gave the FDA the authority to regulate prescription drug labeling and advertising, but the FDA did not establish regulations until 1969. These required that ads for prescriptions include information on their major side effects and contraindications, and unless they have "adequate provision" via different outlets, a "brief summary" of all side effects and contraindications. Pharmaceutical companies shifted the focus of their marketing efforts to licensed medical doctors in the 1970s, as the FDA mandated that only doctors could prescribe medicine. However, a larger movement towards autonomy in health care decisions prompted the first prominent examples of direct-to- consumer advertising.
It does not cure HIV/AIDS or hepatitis B. It is available by mouth as a tablet or powder. Common side effects include nausea, rash, diarrhea, headache, pain, depression, and weakness. Severe side effects include high blood lactate and an enlarged liver. There are no absolute contraindications.
The apparatus is moved slowly across the surface of the part being treated. Ultrasound is a very effective agent for the application of heat, but it should be used only by a therapist who is fully aware of its potential hazards and the contraindications for its use.
Side effects are the same as per the individual components, with stomach or bowel upset from the flucloxacillin being the most common. Both parts are members of the penicillin family of antibiotics, so should not be taken by patients allergic to penicillin. See flucloxacillin for additional contraindications.
Once documented the benign nature of the nodule, the selection criteria for treatment with the laser concern injuries sufficiently massive to create cosmetic damages or local compressive symptoms and those patients who have contraindications at surgery or anesthesia or will not, for aesthetic reasons, to undergo surgery.
Generally, the use of acetazolamide is preferred, but dexamethasone can be used for prevention if there are side effects or contraindications. Some individuals are more susceptible to HACE than others, and physical fitness is not preventive. Age and sex do not by themselves affect vulnerability to HACE.
SCS may be contraindicated in people who have coagulation related disorders, or are on anticoagulant therapy. Other contraindications include local and systemic infection, pacemakers, or those people for whom pre-surgical imaging studies show have anatomy that makes placement difficult, or if concerns arise during psychological evaluation.
Contraindications of Combigan include the following: reactive airway disease including bronchial asthma, a history of bronchial asthma, severe chronic obstructive pulmonary disease, sinus bradycardia, secondary or third degree atrioventricular block, overt cardiac failure, cardiogenic shock, age less than 2 years, and hypersensitivity to any component of Combigan.
Short term use is not encouraged. Contraindications for the device are certain eating disorders (i.e. bulimia), certain types of previous abdominal surgery, pregnancy, stomach ulcers and inflammatory bowel disease. Side effects reported are local skin irritation at the port site and abdominal discomfort, nausea, vomiting, constipation, and diarrhea.
95% of patients report dry-eye symptoms after LASIK. Although it is usually temporary, it can develop into chronic and severe dry eye syndrome. Quality of life can be severely affected by dry-eye syndrome. Underlying conditions with dry eye such as Sjögren's syndrome are considered contraindications to Lasik.
Glucocorticoids have been found to be as effective as NSAIDs and may be used if contraindications exist for NSAIDs. They also lead to improvement when injected into the joint. A joint infection must be excluded, however, as steroids worsen this condition. There were no short-term adverse effects reported.
A radical mastectomy defect (hole) requiring a great volume of replacement tissue. A medical history of radiation to the chest wall. A large opposite breast, which is difficult to match with a pectoral implant; and a previous, failed reconstruction with a breast implant. ;Contraindications The woman is not a suitable patient for a free-flap breast reconstruction surgical procedure if she has any of the following symptoms, or a combination of these symptoms: ASA III or an ASA IV surgical-health grade, a blood coagulation disorder, an unstable psychiatric disease, a BMI > 35 obesity grade, a previous surgery that interrupted the blood supply to the DIEAP free flap, or contraindications to anticoagulation therapy.
Flumazenil (Romazicon) is a competitive benzodiazepine receptor antagonist that can be used as an antidote for benzodiazepine overdose. Its use, however, is controversial as it has numerous contraindications. It is contraindicated in patients who are on long-term benzodiazepines, those who have ingested a substance that lowers the seizure threshold, or in patients who have tachycardia, widened QRS complex on ECG, anticholinergic signs, or a history of seizures. Due to these contraindications and the possibility of it causing severe adverse effects including seizures, adverse cardiac effects, and death, in the majority of cases there is no indication for the use of flumazenil in the management of benzodiazepine overdose as the risks in general outweigh any potential benefit of administration.
Contraindications for surgery are severe pressure sores, severe spasticity, inability to stabilize the trunk. Spasticity, if present, can be very important. It is not a contraindication per se, but severe spasticity must be treated first depending in which muscle groups it is present. Spascticity can be treated with botox or myotomies.
A contraindication specifically for posterior deltoid to triceps transfer is a flexion contracture of the elbow, biceps to triceps transfer might then be a possible transfer for elbow extension reconstruction. The contraindications for biceps-to-triceps transfer relate to the muscle balance surrounding the elbow. The m. supinator and m.
It is contraindicated with herpetic and other viral eye infections. Other contraindications include fungal and mycobacterial infections because tobramycin is inactive against those, and the corticoid acts as an immunosuppressive agent, preventing the body's immune system from dealing with the infection. The drops are also contraindicated in patients with corneal lesions.
In the absence of compelling indications or contraindications, patients should take alpha blockers as a step 4 therapy to reduce blood pressure, but only if the use of ACE inhibitors, angiotensin-II receptor blockers, calcium channel blockers, or thazide diuretics (in full dose or in combinations) have not been efficacious.
Although chemotherapy can shrink germinomas, it is not generally recommended alone unless radiation has contraindications. In a study in the early 1990s, carboplatinum, etoposide, and bleomycin were given to 45 germinoma patients, and about half the patients relapsed. Most of these relapsed patients were then recovered with radiation or additional chemotherapy.
People with serious spinal disease, such as cancer or infection, are not good candidates for acupuncture. Contraindications to acupuncture (conditions that should not be treated with acupuncture) include coagulopathy disorders (e.g. hemophilia and advanced liver disease), warfarin use, severe psychiatric disorders (e.g. psychosis), and skin infections or skin trauma (e.g. burns).
Contraindications include known allergies to cefovecin or antibiotics containing β-lactam rings such as penicillin or cephalosporins. Adverse reactions can include anaphylaxis. It is not for use in humans and should be kept out of reach of children. People with similar known allergies should avoid dermal contact when handling cefovecin.
The use of blood recovered from the operative field is contraindicated in the presence of bacterial contamination or malignancy. The use of autotransfusion in the presence of such contamination may result in the dissemination of pathologic microorganisms or malignant cells. The following statements reflect current clinical concerns involving autotransfusion contraindications.
Many forms of female-controlled contraception rely on suppression of the menstrual cycle using progesterones and/or estrogens. For patients who wish to avoid hormonal medications because of personal medical contraindications such as breast cancer, unacceptable side effects, or personal preference, tubal ligation offers highly effective birth control without the use of hormones.
Contraindications are severe respiratory or liver impairment and acute alcoholism. There are limited accounts of cross-reactivity with opioids, but there is a possibility. Serious central nervous system (CNS) and respiratory depression may also occur with concurrent use of CNS depressants, ingesting alcohol, or other CNS depressing factors while on buprenorphine/naloxone.
Manufacturers are obligated to report documented adverse effects to the FDA. The FDA recommends speaking with a healthcare professional before using dietary supplements. Ingredients in pre-workout can have negative side effects or contraindications with other medications. Taking dietary supplements may have life-threatening consequences if taken with pre-existing health conditions.
Gynatren is contraindicated in patients with a history of allergic reaction to the bacterial antigens or phenol contained in the vaccine. Further contraindications are acute fever, active tuberculosis, severe hematopoietic disorders, decompensated cardiac or renal insufficiency, autoimmune and immunoproliferative diseases. Gynevac is additionally contraindicated in arthritides affecting several joints, under immunosuppressive- or radiotherapy.
For patients who require high dose of corticosteroids for clearing or maintenance, glucocorticoid sparing agents such as immunosuppressive drugs and anti-inflammatory drugs can be used as an adjunct therapy to reduce the systemic side effects of corticosteroids. Patients who have comorbidities and contraindications for corticosteroids may also consider these glucocorticoid sparing agents.
Endovascular repair is the current gold standard due to increased success rates and lower complications. Patients that are able to undergo endovascular repair without contraindications should proceed with it. Repair should be delayed if there is life-threatening intra- abdominal or intracranial bleeding or if the patient is at risk for infection.
People with potential for large amputations and who present within 24 hours of injury can be given TPA with heparin. These medications should be withheld if there are any contraindications. Bone scans or CT angiography can be done to assess damage. Blood vessel dilating medications such as iloprost may prevent blood vessel blockage.
Common side effects are belching, bloating, stomach discomfort or upset, nausea, vomiting, indigestion, dizziness, and flushing. Uncommon and rare side effects include angina, palpitations, hypersensitivity, itchiness, rash, hives, bleeding, hallucinations, arrhythmias, and aseptic meningitis. Contraindications include intolerance to pentoxifylline or other xanthine derivatives, recent retinal or cerebral haemorrhage, and risk factors for haemorrhage.
The indications for the operation in general are as follow: # patients with primary or posttraumatic osteoarthritis with relatively low functional demand; # patients with severe ankle rheumatoid arthritis but not severe osteoporosis of the ankle; # patients suitable for arthrodesis but rejecting it. The general contraindications are: # varus or valgus deformity greater than 15 degrees, severe bony erosion, severe talus subluxation; # substantial osteoporosis or osteonecrosis particularly affecting the talus; # previous or current infections of the foot; # vascular disease or severe neurologic disorders; # previous arthrodesis of the ipsilateral hip or knee or severe deformities of these joints. Other potential contraindications such as capsuloligamentous instability and hindfoot or forefoot deformities affecting correct posture, are not considered relevant if resolved before or during this surgery.
Other side-effects are: gastrointestinal upset, headache and hypersensitivity reactions. The safety of sulfonylurea therapy in pregnancy is unestablished. Prolonged hypoglycemia (4 to 10 days) has been reported in children borne to mothers taking sulfonylureas at the time of delivery. Impairment of liver or kidney function increase the risk of hypoglycemia, and are contraindications.
Women with "undiagnosed abnormal genital bleeding; known or suspected estrogen-dependent neoplasia; active or history of deep vein thrombosis; pulmonary embolism; arterial thromboembolic disease; and are or may become pregnant" or "with known or suspected breast cancer or those with extreme hepatic impairment" should not take ospemifene. This is not a full list of contraindications.
Some medical conditions may temporarily or permanently disqualify a person from diving depending on severity and the specific requirements of the registration body. These conditions may also require the diver to restrict the scope of activities or take specific additional precautions. They are also referred to as relative contraindications, and may be acute or chronic.
Nausea is a common side effect of IV administration and less common in other modes. Antiemetics can be given prior to DHE to counteract the nausea. Risks and contraindications are similar to the triptans. DHE and triptans should never be taken within 24 hours of each other due to the potential for coronary artery vasospasm.
"Yin deficiency, deficiency of essence, and external asthenia and sweating" (due to Wei Qi deficiency) are traditional contraindications. It has been noted to interfere with drugs for diabetes. It can cause allergic reactions in those who are allergic to ragweed, marigolds, daisies, or related herbs (Asteraceae). It should not be used by pregnant women or women who are breastfeeding.
Tenofovir disoproxil is generally well tolerated with low discontinuation rates among the HIV and chronic hepatitis B population. There are no contraindications for use of this drug. The most commonly reported side effects due to use of tenofovir disoproxil were dizziness, nausea, and diarrhea. Other adverse effects include depression, sleep disturbances, headache, itching, rash, and fever.
Veneer placement should be limited to individuals with significant aesthetic problems, such as badly cracked or broken teeth, that do not meet the requirements for a crown or full replacement. Additional contraindications include but are not limited to the following: poor oral hygiene, uncontrolled gingival disease, high caries rate, parafunction, no enamel, unreasonable patient expectations, large existing restorations.
Despite such concerns, no immediate or delayed adverse effects have been reported with routine NCS.. No known contraindications exist from performing needle EMG or NCS on pregnant patients. In addition, no complications from these procedures have been reported in the literature. Evoked potential testing, likewise, has not been reported to cause any problems when it is performed during pregnancy.
His works have been lost, though some are reflected in the writings of Oribasius and Paul of Aegina. He developed specific instructions for a number of operations. He also listed the indications and contraindications and described the complications that could arise from the operations. His operation for aneurysm remained the standard procedure until the 19th century.
It is recommended that medical treatment for missed abortion with misoprostol should only be considered in people without the following contraindications: suspected ectopic pregnancy, use of non-steroidal drugs, signs of pelvic infections or sepsis, unstable hemodynamics, known allergy to misoprostol, previous caesarean section, mitral stenosis, hypertension, glaucoma, bronchial asthma, and remote areas without a hospital nearby.
Treatment is largely symptomatic. Oprelvekin also has caused quite often fluid retention, ranging from peripheral edema (approximately 40% of patients) to dyspnea and full developed lung edema with or without cardiac decompensation (see contraindications and precautions). These symptoms have led to some deaths. Fluid retention may also lead to dilutional anemia (in 10 to 15% of patients).
It further recommends the use of bupivacaine and fentanyl to establish the block. Cautions and contraindications are very similar to those for epidural anaesthesia. Practitioners who make frequent use of the CSE technique for labour analgesia may note unexpected benefits. One example is in the event that the epidural catheter is unintentionally placed into a blood vessel.
The preferred modality is a multi-phasic computed topography (CT) urography. This is a three-phase study that includes a non-contrast phase, an arterial phase, and an excretory phase. The study should sufficiently evaluate the kidney and the urothelium lining the upper urinary tracts. If there are contraindications to this study then alternative studies can be used.
Specialists developed indications and contraindications to the medical treatment in the region of the Caucasian Mineral Waters – for adults, teenagers, and children. These indicators are developed in consideration of the character of natural medicinal properties available in the resorts as well as climatic and geographical features of the region and its influence on the health and illness of people.
Contraindications, conditions that warrant withholding treatment with lovastatin, include pregnancy, breast feeding, and liver disease. Lovastatin is contraindicated during pregnancy (Pregnancy Category X); it may cause birth defects such as skeletal deformities or learning disabilities. Due to its potential to disrupt infant lipid metabolism, lovastatin should not be taken while breastfeeding. Patients with liver disease should not take lovastatin.
This "stress test" is usually not performed if there are any signs of premature birth, placenta praevia, vasa praevia, cervical incompetence, multiple gestation, previous classic caesarian section. Other contraindications include but are not limited to previous uterine incision with scarring, previous myomectomy entering the uterine cavity, and PROM. Any contraindication to labor is contraindication to CST.
Intravenous and oral atropine may be used to treat pyloric stenosis. It has a success rate of 85-89% compared to nearly 100% for pyloromyotomy, however it requires prolonged hospitalization, skilled nursing and careful follow up during treatment. It might be an alternative to surgery in children who have contraindications for anesthesia or surgery, or in children whose parents do not want surgery.
General contraindications to radiosurgery include excessively large size of the target lesion, or lesions too numerous for practical treatment. Patients can be treated within one to five days as outpatients. By comparison, the average hospital stay for a craniotomy (conventional neurosurgery, requiring the opening of the skull) is about 15 days. The radiosurgery outcome may not be evident until months after the treatment.
Other than the overall health of the patients, there are no absolute contraindications. In some lung-disease patients, the lung will not expand after removal of the pleural peel, rendering the surgery futile. Other diseases that render decortication futile are narrowing of the large airway stenosis and uncontrolled pleural infection. With these conditions, the lung will not expand to fill the thorax space.
Citalopram and escitalopram: QT interval prolongation—new maximum daily dose restrictions (including in elderly patients), contraindications, and warnings. From Medicines and Healthcare products Regulatory Agency. Article date: December 2011 In overdose, fluoxetine has been reported to cause sinus tachycardia, myocardial infarction, junctional rhythms and trigeminy. Some authors have suggested electrocardiographic monitoring in patients with severe pre-existing cardiovascular disease who are taking SSRIs.
This technique shares the contraindications and complications of both epidural and spinal anaesthesia. CSE in labouring women is associated with more pruritus if fentanyl (25μg) is given intrathecally, than low-dose epidural analgesia. However, no difference has been found in the incidence of post dural puncture headache, requirement for epidural blood patch or maternal hypotension.Simmons SW, Cyna AM, Dennis AT et al.
During the procedure, delivery of focused ultrasound energy is guided and controlled using MR thermal imaging. Patients who have symptomatic fibroids, who desire a non-invasive treatment option and who do not have contraindications for MRI are candidates for MRgFUS. About 60% of patients qualify. It is an outpatient procedure and takes one to three hours depending on the size of the fibroids.
After appraising the evidence, it is necessary to integrate it with the provider's expertise and patient's preferences. The patient is encouraged to practice autonomy and participate in the decision-making process. Therefore, even if the study had successful outcomes, the patient may refuse to receive a treatment. Assessment findings and patient history may reveal further contraindications to a certain evidence-based treatment.
The "nonlifting sign" and complaints of pain when the snare strangulates the lesion are contraindications to doing the procedure. When perforation is recognized immediately afterwards, the perforation should be closed by clips. Surgery should be considered in cases of endoscopic closure failure. The incidence of complications ranges from 0–50% and recurrence of esophageal squamous cell carcinoma range from 0–8%.
Nicotine use for tobacco cessation has few contraindications. It is not known whether nicotine replacement therapy is effective for smoking cessation in adolescents, as of 2014. It is therefore not recommended to adolescents. It is not safe to use nicotine during pregnancy or breastfeeding, although it is safer than smoking; the desirability of NRT use in pregnancy is therefore debated.
Liver transplantation is a potential treatment for acute or chronic conditions which cause irreversible and severe ("end-stage") liver dysfunction. Since the procedure carries relatively high risks, is resource-intensive, and requires major life-modifications after surgery, it is reserved for dire circumstances. Judging the appropriateness/effectiveness of liver transplant on case-by-case basis is critically important (see Contraindications), as outcomes are highly variable.
The correct use and properly fitted graded compression stockings can reduce the rate of thrombosis by 50%. Contraindications for the use of antiembolism stockings include the presence of advanced peripheral and obstructive arterial disease, septic phlebitis, heart failure, open wounds, dermatitis and peripheral neuropathy. Differences between the use of thigh-high compression stockings and shorter types to prevent blood clots exist, but remain inconsistent.
Some websites offer medications without a prescription or a doctor review. This practice has been criticized as potentially dangerous, especially by those who feel that only doctors can reliably assess contraindications, risk/benefit, and the suitability of a medication for a specific individual. Pharmacies offering medication without requiring a prescription, doctor review, or supervision are sometimes fraudulent and may supply counterfeit, ineffective, and possibly dangerous medicines.
There are no absolute contraindications to cardiopulmonary bypass. However, there are several factors that need to be considered by the care team when planning an operation. Heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia and thrombosis (HITT) are potentially life-threatening conditions associated with the administration of heparin. In HIT or HITT, antibodies against heparin are formed which causes platelet activation and the formation of blood clots.
Patients who are Rh-negative are usually given anti-D immune globulin to prevent RhD isoimmunization. The fetal heart rate can also be checked to assess the need for delivery. Ectopic pregnancy is treated with methotrexate therapy or surgery. Surgery is required for patients who have failed or have contraindications to methotrexate therapy, are experiencing significant blood loss, or have signs of ectopic rupture.
To prevent complications, individuals should not use pessaries if they have characteristics that exclude them from this method of therapy. Contraindications to pessary use include current infections in the pelvis or vagina, or allergies to the material of the pessary (which can be silicone or latex). In addition, individuals should not be fitted for a pessary if they are less likely to properly maintain their pessary.
Science and medicine are areas where accuracy is of high importance and peer review is the norm. While some of Wikipedia's content has passed a form of peer review, most has not. A 2008 study examined 80 Wikipedia drug entries. The researchers found few factual errors in this set of articles, but determined that these articles were often missing important information, like contraindications and drug interactions.
Contraindications for nandrolone decanoate include pregnancy, breastfeeding, prostate cancer, male breast cancer, breast cancer in women with hypercalcemia, hypersensitivity (to nandrolone decanoate or excipients such as arachis (peanut) oil; includes those with peanut and soy allergies), nephrosis or nephritis, liver disease with impaired bilirubin excretion, and heart failure. High dosages may also be considered contraindicated in women due to their high potential for virilization.
Pregnancy is considered a relative contraindication, similarly to many forms of medical imaging in pregnancy. The potential harms to a fetus include the application of X-rays in addition to radiocontrast. Since an iodine-containing contrast agent is used, severe contrast agent allergy, uncontrolled hyperthyroidism or renal function impairment are also relative contraindications. Cardiac arrhythmias, coronary artery stents and tachycardia may result in a reduced image quality.
The general principles for disqualification are that diving causes a deterioration in the medical condition and the medical condition presents an excessive risk for a diving injury to both the individual and the diving partner. There are some conditions that are considered absolute contraindications for diving. Details vary between recreational and professional diving and in different parts of the world. Those listed below are widely recognised.
Contraindications of combined birth control pills, such as those containing EE and CMA, include known or suspected pregnancy, lactation and breastfeeding, a history of or known susceptibility to thromboembolism, cholestasis (but not liver cirrhosis or chronic hepatitis), and breast cancer among others. CMA is a teratogen in animals and may have the potential to cause fetal harm, such as feminization of male fetuses among other defects.
Devocalization is usually performed at the request of an animal owner (where the procedure is legally permitted). The procedure may be forcefully requested as a result of a court order. Owners or breeders generally request the procedure because of excessive animal vocalizations, complaining neighbors, or as an alternative to euthanasia due to a court order. Contraindications include negative reaction to anesthesia, infection, bleeding, and pain.
The procedure is contraindicated in pregnancy. Therefore, women in the reproductive years may need a pregnancy test before a biopsy is taken to assure that the test is not done during a pregnancy. Other contraindications are pelvic inflammatory disease and coagulopathies. An endometrial biopsy usually cannot be done as an office procedure in children, young women, women with vaginismus, or women with cervical stenosis.
Also Beta-receptor antagonists should be avoided in patients with AV node dysfunction and/or patients on other medications which might cause bradycardia (i.e. calcium channel blockers). The potential for these contraindications and drug-drug interaction could lead to asystole and cardiac arrest. Certain calcium channel blocker should be avoided with some beta-receptor blockers since they may cause severe bradycardia and other potential side effects.
Stenting, as well as the insertion of coils by means of angiography, may be performed if there is an aneurysm and/or extension of the dissection into the V4 section of the artery. Surgery carries a high risk of complications, and is typically only offered in case of inexorable deterioration or contraindications to any of the other treatments. Various arterial repair procedures have been described.
The US approval lists the thyroid C cell cancers medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia type 2 (MEN 2) as contraindications because other GLP-1 agonists are known to cause such cancers in rodents. Albiglutide causes immunogenicity in rodents, so its cancer risk could not be assessed.Drugs.com: on Tanzeum. The European approval mentions the uncertainty about C cell cancers, but not as a contraindication.
Contraindications of spironolactone include hyperkalemia (high potassium levels), severe and end-stage kidney disease (due to high hyperkalemia risk, except possibly in those on dialysis), Addison's disease (adrenal insufficiency and low aldosterone levels), and concomitant use of eplerenone. It should also be used with caution in people with some neurological disorders, no urine production, acute kidney injury, or significant impairment of kidney excretory function with risk of hyperkalemia.
Iodinated contrast agents may cause allergic reactions, contrast-induced nephropathy, hyperthyroidism and possibly metformin accumulation. However, there are no absolute contraindications to iodinated contrast, so the benefits needs to be weighted against the risks. Page last modified on 26/7/2017 In people with myasthenia gravis, older forms of iodinated contrast have caused an increased risk of exacerbation of the disease, but modern forms have no immediate increased risk.
The main professionals that provide therapeutic massage are massage therapists, athletic trainers, physical therapists and practitioners of many traditional Chinese and other eastern medicines. Massage practitioners work in a variety of medical settings and may travel to private residences or businesses. Contraindications to massage include deep vein thrombosis, bleeding disorders or taking blood thinners such as Warfarin, damaged blood vessels, weakened bones from cancer, osteoporosis, or fractures, and fever.
In 2013, the company purchased the Epocrates mobile brand, and continued to occupy Epocrates's offices in Princeton, New Jersey and San Francisco, California. As an athenahealth service, Epocrates aggregates treatment information, including dosing and contraindications, to provide clinical decision support in the prescribing moments of care. Epocrates drug monographs have also been embedded into the athenaClinicals EHR system to enhance productivity and reduce time not spent on patients.
CEPP is an acronym for the name of a chemotherapy regimen that is intended for treatment of aggressive non-Hodgkin lymphomas. Unlike CHOP, this chemotherapy regimen does not contain doxorubicin or any other anthracycline. Thus, it can be used in patients with severe cardiovascular diseases and contraindications for doxorubicin-containing regimens. There are 2 modifications of CEPP - with the addition of bleomycin, called CEPP (B), and without bleomycin - ordinary CEPP.
Lymphatic pump treatment (LPT) is a manual technique intended to encourage lymph flow in a person's lymphatic system. The first modern lymphatic pump technique was developed in 1920, although osteopathic physicians used various forms of lymphatic techniques as early as the late 19th century. Relative contraindications for the use of lymphatic pump treatments include fractures, abscesses or localized infections, and severe bacterial infections with body temperature elevated higher than .
In the US, daclizumab is contraindicated in people with liver impairment, including significantly elevated liver enzymes (ALT, AST) and autoimmune hepatitis. for Zinbryta. The European Medicines Agency (EMA) originally approved the drug without any contraindications apart from known hypersensitivity, but required Biogen to implement a hepatic risk management guide for physicians. In July 2017, the EMA has issued a provisional contraindication for patients with pre-existing liver disease or liver impairment.
As with other triptans, almotriptan should not be used in patients with a history, symptoms or signs of ischaemic heart disease (myocardial infarction, angina pectoris, documented silent ischaemia, Prinzmetal’s angina) or severe hypertension and uncontrolled mild or moderate hypertension. Other contraindications are previous cerebrovascular accident (CVA) or transient ischaemic attack (TIA), peripheral vascular disease, severe hepatic impairment, concomitant administration of ergotamine, ergotamine derivatives (including methysergide) and other 5-HT1B/D agonists.
Any contraindications that apply to peg-IFN and RBV apply to simeprevir since they must be used in combination during treatment of CHC. For example, people with sickle cell anemia are contraindicated to RBV therapy and are therefore contraindicated to simeprevir and peg-IFN combination therapy. Pregnant women and men whose female partners are pregnant are contraindicated for simeprevir since peg-IFN and RBV are known to cause birth defects.
There are no specific contraindications for cholecystectomy, and in general it is considered a low- risk surgery. However, anyone who cannot tolerate surgery under general anesthesia should not undergo cholecystectomy. People can be split into high and low risk groups using a tool such as the ASA physical status classification system. In this system, people who are ASA categories III, IV, and V are considered high risk for cholecystectomy.
Women who are known to be pregnant should not take COCPs. Postpartum women who are breastfeeding are also advised not to start COCPs until 4 weeks after birth due to increased risk of blood clots. Severe hypercholesterolemia and hypertriglyceridemia are also currently contraindications, but the evidence showing that COCP's lead to worse outcomes in this population is weak. Obesity is not considered to be a contraindication to taking COCPs.
Since glycylcyclines are similar to tetracyclines, they share many of the same side effects and contraindications as tetracyclines. These side effects may include nausea/vomiting, headache, photosensitivity, discoloration of growing teeth, and fetal damage. These antibiotics should not be given to pregnant women due to risk of fetal harm. Additionally, these drugs should not be administered during periods of tooth development because of the risk of tooth discoloration.
Benzodiazepines themselves can trigger or worsen delirium, and there is no reliable evidence for use in non-alcohol-related delirium. If the delirium involves alcohol withdrawal, benzodiazepine withdrawal, or contraindications to antipsychotics (e.g. in Parkinson's disease or neuroleptic malignant syndrome), then benzodiazepines are recommended. Similarly, people with dementia with Lewy bodies may have significant side effects to antipsychotics, and should either be treated with a none or small doses of benzodiazepines.
The two contraindications to taking ezetimibe are a previous allergic reaction to it, including symptoms of rash, angioedema, and anaphylaxis, and severe liver disease, especially when taken with a statin.U.S. National Library of Medicine, National Institutes of Health, U.S. Department of Health and Human Services. Page last updated: 27 October 2014 Medline Plus: Ezetimibe Ezetimibe may have significant medication interactions with ciclosporin and with fibrates other than fenofibrate.Zetia label, Rev 23.
Breastfeeding research continues to assess prevalence, HIV transmission, pharmacology, costs, benefits, immunology, contraindications, and comparisons to synthetic breast milk substitutes. Factors related to the mental health of the nursing mother in the perinatal period have been studied. While cognitive behavior therapy may be the treatment of choice, medications are sometimes used. The use of therapy rather than medication reduces the infant's exposure to medication that may be transmitted through the milk.
Contraindications include hypersensitivity to abiraterone acetate. Although documents state that it should not be taken by women who are or who may become pregnant, there is no medical reason that any woman should take it. Women who are pregnant should not even touch the pills unless they are wearing gloves. Other cautions include severe baseline hepatic impairment, mineralocorticoid excess, cardiovascular disease including heart failure and hypertension, uncorrected hypokalemia, and adrenocorticoid insufficiency.
Ongoing trials compare various combinations of chemotherapy; the phase II/III REAL-2 trial – for example – compares four regimens containing epirubicin and either cisplatin or oxaliplatin, and either continuously infused fluorouracil or capecitabine. Radiotherapy is given before, during, or after chemotherapy or surgery, and sometimes on its own to control symptoms. In patients with localised disease but contraindications to surgery, "radical radiotherapy" may be used with curative intent.
Generally, there are no specific contraindications to having a cystectomy. However, cystectomy should not be performed in individuals who are not healthy enough to undergo a major surgical procedure. This includes individuals who cannot tolerate general anesthesia or those with severe or inadequately managed co-morbidities such as diabetes, heart, lung, kidney, or liver disease. This also includes individuals who are severely malnourished, have problems with blood clotting, or severe laboratory abnormalities.
In addition, in older patients and in patients with heart failure, a slow heart rate, underlying cardiac disease, and those with renal impairment, monitoring with electrocardiography is indicated when this drug is used. Congenital long- QT syndrome and drugs that prolong the PR or QRS interval are contraindications to dolasetron therapy. Dolasetron injection may still be used for the prevention and treatment of postoperative nausea and vomiting, per Food and Drug Administration guidelines.
Aside from effects in the brain, the general physical risks of ECT are similar to those of brief general anesthesia; the U.S. Surgeon General's report says that there are "no absolute health contraindications" to its use. Immediately following treatment, the most common adverse effects are confusion and memory loss. Some patients experience muscle soreness after ECT. This is invariably due to the muscle relaxants given during the procedure, rather than caused by muscle activity.
Other absolute contraindications to receiving an intestinal transplant include the presence of systemic and untreated local infections, malignant cancer, severe neurological impairment, and severe cardiac and/or pulmonary disease. These criteria are similar to established guidelines for transplants of other organ types. HIV infection is a relative contraindication for intestine transplantation; desperate terminal patients may accept a transplant from a HIV-positive donor if they are willing to expose themselves to HIV.
A woman may not be a good candidate for the procedure. Contraindications for this treatment are having a current urinary tract infection, having difficulty emptying the bladder, having a urethral stricture, having a urethral obstruction or having fragile or sensitive tissue where the injections are to be placed. In some women, cancer treatments may have created changes in the urethra, bladder and sphincter muscles which would prevent the success of the treatment.
In 2015, flibanserin was approved in the US to treat decreased sexual desire in women. While it's effective for some women, it has been criticized for its limited efficacy, and many warnings and contraindications that limit its use. name=WebMD Women experiencing pain with intercourse are often prescribed pain relievers or desensitizing agents; others can be prescribed vaginal lubricants. Many women with sexual dysfunction are also referred to a counselor or sex therapist.
One of the safety concerns identified before approval was fluid retention. Moreover, the combination of rosiglitazone with insulin resulted in a higher rate of congestive heart failure. In Europe there were contraindications for use in heart failure and combination with insulin. A meta analysis of all trials from 2010 and 2019 confirmed a higher risk of heart failure and a double risk when rosiglitazone was administered as add-on therapy to insulin.
Contraindications to its use include renovascular disease (impaired blood flow in the kidneys), severe kidney impairment (especially in patients with one kidney or with bilateral renal artery stenosis), volume-depleted patients, a history of angioedema while on an ACE inhibitors, pregnancy and hypotension. People should not take ramipril (or any ACE inhibitors) if they have hyperkalemia. It is also recommended to avoid using salt-substitutes as this can further increase potassium levels in the blood.
Hypokalemia may also result. Symptoms of fluid retention have been observed more often in patients following myeloablative chemotherapy (see contraindications). Severe arrhythmias (atrial flutter and atrial fibrillation) as well as fatal cardiac arrest have also been seen which may or may be not attributed to fluid retention/increased volume. Isolated cases of stroke have been noted, those patients with previous transient ischemic attacks or partial/minor strokes may be at particular risk.
Most people develop symptoms of estrogen deficiency, including vasomotor flushes and vaginal dryness, both of which respond to hormone replacement therapy. There are several contraindications of estrogen supplement, including smokers over 35 years of age, uncontrolled hypertension, uncontrolled diabetes mellitus, or history of thromboemboli events. Women younger than 40 year with POI benefit from physiologic replacement of hormones. Most authorities recommend that this hormone replacement continue until age 50 years, the normal age of menopause.
Typically, tissue plasminogen activator may be administered within 3 to 4.5 hours of stroke onset if the patient is without contraindications (i.e. a bleeding diathesis such as recent major surgery or cancer with brain metastases). High dose aspirin can be given within 48 hours. For long term prevention of recurrence, medical regimens are typically aimed towards correcting the underlying risk factors for lacunar infarcts such as hypertension, diabetes mellitus and cigarette smoking.
Some cases of acute kidney injury either requiring dialysis or having a fatal outcome following Reclast use have been reported to the U.S. Food and Drug Administration (FDA). This assessment was confirmed by the European Medicines Agency (EMA), whose Committee for Medicinal Products for Human Use (CHMP) specified new contraindications for the medication on 15 December 2011, which include hypocalcaemia and severe renal impairment with a creatinine clearance of less than 35 ml/min.
For a small number of people, taking aspirin can result in symptoms including hives, swelling, and headache. Aspirin can exacerbate symptoms among those with chronic hives, or create acute symptoms of hives. These responses can be due to allergic reactions to aspirin, or more often due to its effect of inhibiting the COX-1 enzyme. Skin reactions may also tie to systemic contraindications, seen with NSAID-precipitated bronchospasm, or those with atopy.
Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, in alcohol- or other drug- dependent individuals or those with comorbid psychiatric disorders. Additional caution is required in critically ill patients, as accumulation of midazolam and its active metabolites may occur. Kidney or liver impairments may slow down the elimination of midazolam leading to prolonged and enhanced effects. Contraindications include hypersensitivity, acute narrow-angle glaucoma, shock, hypotension, or head injury.
Retrograde pyelography is generally done when an intravenous excretory study (intravenous pyelogram or contrast CT scan) cannot be done because of renal disease or allergy to intravenous contrast. Relative contraindications include the presence of infected urine, pregnancy (because of radiation), or allergy to the contrast. Because a pyelogram involves cystoscopy, it may cause sepsis, infection or bleeding, and may also cause nausea and vomiting. The dye may also be toxic to the kidneys.
Intrahepatic cholestasis of pregnancy (acute or in history), vaginal bleeding of unknown origin, and severe diseases of the liver such as tumors are absolute contraindications for medrogestone, as are thrombotic events such as thrombophlebitis or stroke. Medrogestone is contraindicated during pregnancy because progestogens are associated with risks for the fetus in animals and humans. It is not known whether medrogestone passes into breast milk, but it is to be expected given its lipophilicity and studies with structurally related progestins.
If another episode of PE occurs under warfarin treatment, the INR window may be increased to e.g. 2.5–3.5 (unless there are contraindications) or anticoagulation may be changed to a different anticoagulant e.g. LMWH. In recent years, a number of anticoagulants have been introduced that offer similar to warfarin but without a need for titration to the INR. Known as the directly acting oral anticoagulants, these treatments are now preferred over vitamin K antagonists by American professional guidelines.
For individuals with few symptoms, or those with contraindications to surgery, options exist for medical treatment in both mitral insufficiency and mitral valve stenosis, although they won't cure the conditions. Such medical treatments include diuretics,VOC=VITIUM ORGANICUM CORDIS, a compendium of the Department of Cardiology at Uppsala Academic Hospital. By Per Kvidal September 1999, with revision by Erik Björklund May 2008 Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease vasodilators, and ACE inhibitors.
In this select population who are naive to and overdose solely on a benzodiazepine, it can be considered. Due to its short half life, the duration of action of flumazenil is usually less than 1 hour, and multiple doses may be needed. When flumazenil is indicated the risks can be reduced or avoided by slow dose titration of flumazenil. Due to risks and its many contraindications, flumazenil should be administered only after discussion with a medical toxicologist.
A medical and dental history is obtained for completeness. The medical history includes questions on the general health of the patient, to assess contraindications to treatment of jaw abnormality. Special emphasis is placed on diseases and medication which cause altered metabolism, that may affect growth and tissue reactions. Allergies are checked (specifically nickel allergies), so that treatment appliances with nickel-containing materials like stainless steel can be replaced with other materials to avoid the risk of allergic reactions.
Lung transplantation is an option if the ILD progresses despite therapy in appropriately selected patients with no other contraindications. On October 16, 2014, the Food and Drug Administration approved a new drug for the treatment of Idiopathic Pulmonary Fibrosis (IPF). This drug, Ofev (nintedanib), is marketed by Boehringer Ingelheim Pharmaceuticals, Inc. This drug has been shown to slow the decline of lung function although the drug has not been shown to reduce mortality or improve lung function.
Information is easily accessed via drop-down menus.STFM: Child Immunization schedule Shots contains the unified, ACIP-approved childhood, adolescent, adult, catch-up and medical indications schedules for the United States. Drop- down menus provide details about every vaccine and include: Basics, High Risk Indications, Adverse Reactions, Contraindications, Catch-Up, Administration, Risk Communications, Brand Names, Epidemiology and Pictures of Vaccine Preventable Diseases. As new vaccines become available and recommendations are made, they are added to the applications.
Regular aerobic exercise during pregnancy appears to improve (or maintain) physical fitness. Physical exercise during pregnancy does appear to decrease the need for C-section. Bed rest, outside of research studies, is not recommended as there is no evidence of benefit and potential harm. The Clinical Practice Obstetrics Committee of Canada recommends that "All women without contraindications should be encouraged to participate in aerobic and strength-conditioning exercises as part of a healthy lifestyle during their pregnancy".
Improvement of GERD symptoms is similar to those of the Nissen fundoplication, although there is no data regarding long-term effects. Compared to Nissen fundoplication procedures, the procedure has shown a reduction in complications such as gas bloat syndrome that commonly occur. Adverse responses include difficulty swallowing, chest pain, vomiting, and nausea. Contraindications that would advise against use of the device are patients who are or may be allergic to titanium, stainless steel, nickel, or ferrous iron materials.
Clinical studies showed that this mechanism is irrelevant for practical purposes. In November 2009, the U.S. Food and Drug Administration (FDA) announced that clopidogrel should be used with caution in people using the proton-pump inhibitors omeprazole or esomeprazole, but pantoprazole appears to be safe. The newer antiplatelet agent prasugrel has minimal interaction with , hence might be a better antiplatelet agent (if no other contraindications are present) in people who are on these proton-pump inhibitors.
Medical MRI scanner Magnetic resonance imaging (MRI) is in general a safe technique, although injuries may occur as a result of failed safety procedures or human error. During the last 150 years, thousands of papers focusing on the effects or side effects of magnetic or radiofrequency fields have been published. They can be categorized as incidental and physiological. Contraindications to MRI include most cochlear implants and cardiac pacemakers, shrapnel and metallic foreign bodies in the eyes.
Anxiolytic medication aids a patient to handle social or professional situations before more lasting treatment has had an effect and therefore it is a provider of short term relief, but anxiolytics have a risk of dependence. Beta-adrenergic antagonists help to control palpitations and tremors unresponsive to the treatment of anxiolytic medication. One must read the precautions of these drugs outlined in the manufacturer's literature and be careful to watch out for the contraindications of these drugs.
A pharmacist can use both open-ended questions (that start with the word who, what, how, why or where) as well as close-ended questions (that start with the word will, can, do or did) which are to be used only if the former do not get the appropriate response in order to obtain relevant information about a patient's potential needs for treatment or potential drug-therapy problems. Pharmacists ask patients about comorbidities to avoid any drug-disease state contraindications.
Contraindications of elagolix include pregnancy, known osteoporosis, severe hepatic impairment, and concomitant use with strong organic anion-transporting polypeptide (OATP) 1B1 inhibitors such as ciclosporin and gemfibrozil. Elagolix may increase the risk of miscarriage in early pregnancy. Women should avoid pregnancy while taking elagolix, for instance by using birth control, and should discontinue the medication if they become or wish to become pregnant. Elagolix should not be used in women with osteoporosis because it may increase the risk of further bone loss.
According to the FDA-approved prescribing information leaflet, "Common adverse events include inoculation site signs and symptoms, lymphadenitis, and constitutional symptoms, such as malaise, fatigue, fever, myalgia, and headache." These reactions are less frequent in people being revaccinated than those receiving the vaccine for the first time. As far as pregnancy goes, it is recommended that the vaccine should be given to pregnant women who have been exposed to smallpox. No contraindications exist to receiving the vaccine in case of an outbreak emergency.
Eligibility and absolute and relative contraindications should undergo rapid assessment. Randomized controlled trials have shown that intravenous administration of recombinant tissue plasminogen activator (alteplase) decrease functional disability with an absolute reduction risk of 7%-13% relative to placebo.[21] Unfortunately, over half of patients arrive after this time window has closed and are not eligible for thrombolysis. Treatment delays may result from failure to ascribe a patient's symptoms to stroke, and furthermore, the risk of harm increases with time elapsed from symptom onset.
Estrogens like estradiol have a number of contraindications. Estradiol should be avoided when there is undiagnosed abnormal vaginal bleeding, known, suspected or a history of breast cancer, current treatment for metastatic disease, known or suspected estrogen- dependent neoplasia, deep vein thrombosis, pulmonary embolism or history of these conditions, active or recent arterial thromboembolic disease such as stroke, myocardial infarction, liver dysfunction or disease. Estradiol should not be taken by people with a hypersensitivity/allergy or those who are pregnant or are suspected pregnant.
Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening circumstances in the mother. Additional relative contraindications to the use of cyclophosphamide include lactation, active infection, neutropenia or bladder toxicity. Cyclophosphamide is a pregnancy category D drug and causes birth defects. First trimester exposure to cyclophosphamide for the treatment of cancer or lupus displays a pattern of anomalies labeled "cyclophosphamide embryopathy," including growth restriction, ear and facial abnormalities, absence of digits and hypoplastic limbs.
Special diets for dissolution also have reduced protein, phosphorus, and magnesium, as well as increased salt to increase water consumption and dilute the urine. The diet needs to be fed exclusively, but it can only be fed for a few months total due to potential side effects. Contraindications to this diet include heart failure, liver failure, kidney failure, pancreatitis, hypertension (high blood pressure), and hypoalbuminemia (low serum albumin). Prevention of struvite stones is with a similar diet with milder restrictions.
More recent reports have shown that bubbles from even a small amount of sclerosant foam injected into the veins quickly appear in the heart, lung and brain. The significance of this is not fully understood at this point and large studies show that foam sclerotherapy is safe. Sclerotherapy is fully FDA approved in the USA. Contraindications include: bed rest, severe systemic diseases, poor patient understanding, needle phobia, short life expectancy, late stage cancer, known allergy to the sclerosing agent, and treatment with tamoxifen.
MRI is in general a safe technique, although injuries may occur as a result of failed safety procedures or human error. Contraindications to MRI include most cochlear implants and cardiac pacemakers, shrapnel, and metallic foreign bodies in the eyes. Magnetic resonance imaging in pregnancy appears to be safe at least during the second and third trimesters if done without contrast agents. Since MRI does not use any ionizing radiation, its use is generally favored in preference to CT when either modality could yield the same information.
Absolute contraindications, which are reasons why the procedure absolutely cannot be done, include: # Pregnancy is an absolute contraindication to the use of breast irradiation. In some cases, it may be possible to perform breast-conserving surgery in the third trimester and treat the patient with radiation after delivery. # Two or more primary tumors in separate quadrants of the breast or with diffuse malignant-appearing microcalcifications. # A history of prior therapeutic irradiation to the breast that would require re-treatment to an excessively high total dose.
There are physical, physiological, or mental differences in the geriatric population that could potentially lead to poor nutrient intake that would require them to have nutrition therapy. Geriatric patients are more inclined to have delayed muscle restoration compared to the younger population. Additionally, older patients are observed to have greater cardiac and renal impairment, insulin resistance, and to have deficiencies in vitamins and crucial elements. Patients that require nutrition therapy but have contraindications for or cannot tolerate enteral nutrition are appropriate candidates for parenteral nutrition.
Many orthopaedists have challenged these contraindications and have advocated meniscal transplantation, in conjunction with cartilage repair, ACL reconstruction or osteotomy in patients with evidence of arthritic deterioration, instability or malalignment. One paper demonstrated that results of meniscus transplantation in patients with arthritic changes were similar to that of previous reports of meniscus transplantation in patients without arthritic changes, so long as articular cartilage defects were addressed at the time of surgery. In the same paper, the success of meniscus transplantation was not affected by mal-alignment.
During the Islamic Golden Age, the use of opium was discussed in detail by Avicenna (c. 980 – June 1037 AD) in The Canon of Medicine. The book's five volumes include information on opium's preparation, an array of physical effects, its use to treat a variety of illness, contraindications for its use, its potential danger as a poison and its potential for addiction. Avicenna discouraged opium's use except as a last resort, preferring to address the causes of pain rather than trying to minimize it with analgesics.
While there are no absolute contraindications to socket preservation, many of the same cautions that apply to surgery on the jaws still apply to this procedure. Significant caution is required in an area previously exposed to radiation treatment, or in an area that has previously had osteomyelitis. Other considerations to bone healing include the concurrent use of bisphosphonate, and denosumab, smoking, diabetes, immunocompromise, and infection. Another consideration is the risk of bone and soft tissue loss on the subsequent implant in the long-term.
Patients who are candidates for stimulator placement should be screened for contraindications and comorbidities. The following should be considered prior to stimulator trial: Risk of Bleeding – Spinal cord stimulator trial and implant have been identified as procedures with high risk of serious intraspinal bleeding, which can cause permanent neurologic damage. Appropriate planning for discontinuation and reinstitution of anti-platelet and anticoagulant medications is necessary prior to placement of a stimulator. Psychological evaluation – Depression, anxiety, somatization, and hypochondriasis are associated with worse outcomes for Spinal Cord Stimulators.
Use of tPA in the United States in treatment of patients who are eligible for its use, have no contraindications, and arrival at the treating facility less than 3 hours after onset of symptoms, is reported to have doubled from 2003 to 2011. Use on patients with mild deficits, of nonwhite race/ethnicity, and oldest old age increased. However, many patients who were eligible for treatment were not treated. tPA has also been given to patients with acute ischemic stroke above age 90 years old.
Estradiol should not be used in women who are pregnant or breastfeeding or who have breast cancer, among other contraindications. Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men. Estradiol differs from non- bioidentical estrogens like conjugated estrogens and ethinylestradiol in various ways, with implications for tolerability and safety.
Vaginal ultrasound is inexpensive, easily accessible, has no contraindications and requires no preparation. Healthcare professionals conducting ultrasound examinations need to be experienced. By extending the ultrasound assessment into the posterior and anterior pelvic compartments the sonographer is able to evaluate structural mobility and look for deep infiltrating endometriotic nodules noting the size, location and distance from the anus if applicable. An improvement in sonographic detection of deep infiltrating endometriosis will not only reduce the number of diagnostic laparoscopies, it will guide management and enhance quality of life.
A frequently used test for lung function for divers is spirometry, which measures the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled. Spirometry is an important tool used for generating pneumotachographs, which are helpful in assessing conditions such as asthma, pulmonary fibrosis, cystic fibrosis, and COPD, all of which are contraindications for diving. Sometimes only peak expiratory flow (PEF) is measured, which uses a much simpler apparatus, but is still useful to give an indication of lung overpressure risk.
Before placement of an IUD, a medical history and physical examination by a medical professional is useful to check for any contraindications or concerns.Birth Control Intrauterine Devices (IUDs) Author: Omnia M Samra. Last Editorial Review: 5/18/2006 It is also recommended by some clinicians that patients be tested for gonorrhea and chlamydia, as these two infections increase the risk of contracting pelvic inflammatory disease shortly after insertion. Immediately prior to insertion, the clinician will perform a pelvic exam to determine the position of the uterus. p.
Laboratory monitoring is recommended due to potential changes in lymphocytes, neutrophils, hemoglobin, liver enzymes, and lipids. Tofacitinib claims to have no contraindications, but doctors are advised to reduce the patient's dosage when combined with "potent inhibitors of cytochrome P450 3A4 (CYP3A4)," such as ketoconazole, or one or more combined medications that result in both moderate inhibition of CYP3A4 and potent inhibition of CYP2C19 such as fluconazole. Furthermore, immunizations with live vaccines should be avoided by tofacitinib users. According to postmarketing research, tofacitinib may also increase the risk for pulmonary embolism.
Some physical and psychological conditions are known or suspected to increase the risk of injury or death in the underwater environment, or to increase the risk of a stressful incident developing into a serious incident culminating in injury or death. Conditions which significantly compromise the cardiovascular system, respiratory system or central nervous system may be considered absolute or relative contraindications for diving, as are psychological conditions which impair judgement or compromise the ability to deal calmly and systematically with deteriorating conditions which a competent diver should be able to manage.
The most common adverse effect is otic barotrauma, trauma to the inner ear due to pressure not being released on descent. Since hyperbaric oxygen therapy is usually administered daily for a set number of treatments, adverse effects must be prevented in order for the patient to receive all prescribed treatments. The hyperbaric nurse will collaborate with the patient's physician to determine if hyperbaric oxygen therapy is the right treatment. The nurse must know all approved indications that warrant hyperbaric oxygen therapy treatments, along with contraindications to the treatment.
Underdosing of stimulants can occur and result in a lack of response or later loss of effectiveness. This is particularly common in adolescents and adults as approved dosing is based on school-aged children, causing some practitioners to use weight based or benefit based off-label dosing instead. While stimulants and atomoxetine are usually safe, there are side-effects and contraindications to their use. There is low quality evidence of an association between methylphenidate and both serious and non-serious harmful side effects when taken by children and adolescents.
While there are no absolute contraindications to atipamezole, it is recommended against being given with anticholinergics, as both can cause dramatic increases in heart rate. Atipamezole should also not be given too soon after an animal has been given dexmedetomidine mixed with ketamine or telazol(tiletamine); because it reverses only the dexmedetomidine, the ketamine or telazol will still be active, and the animal can wake up excited, delirious, and with muscle contractions. Some recommend not using it in dogs sedated with ketamine at all, since they can convulse due to the excitement effect.
In a double-blind, placebo-controlled trial of 326 people, 4 people had serious adverse events and 61% became resedated following the use of flumazenil. Numerous contraindications to its use exist. It is contraindicated in people with a history of long-term use of benzodiazepines, those having ingested a substance that lowers the seizure threshold or may cause an arrhythmia, and in those with abnormal vital signs. One study found that only 10% of the people presenting with a benzodiazepine overdose are suitable candidates for treatment with flumazenil.
To that end, the program will issue reminders to both the family of the child and the practicing physician to alert of upcoming vaccination appointments. Because the system is integrated statewide, it reduces the chances of over-immunization and reduces missed opportunities when children attend different physicians within a vaccination series. This promises to have a profound impact in Alaska given the state's enormous geographic diversity and rather mobile population. In each record, VacTrAK also stores contraindications, allergies, and other information which a physician will take into account when administering a vaccine.
The Advisory Committee on Immunization Practices (ACIP), is a committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control of vaccine-preventable diseases in the U.S. civilian population. The ACIP develops written recommendations for routine administration of vaccines to the pediatric and adult populations, along with vaccination schedules regarding appropriate timing, dosage, and contraindications of vaccines. ACIP statements are official federal recommendations for the use of vaccines and immune globulins in the U.S., and are published by the CDC.
Ten to forty percent of people will experience nausea, vomiting, abdominal pain, itching skin, increased body temperature, trembling and weakness. One to five percent of peoples may experience back and chest pain, dizziness, anemia, chills and sweating, metallic taste, tachycardia and respiratory distress. Contraindications for the use of carbetocin include inappropriate timing during labor and delivery (such as before parturition or to induce labor) or allergic reactions to carbetocin or other oxytocin homologues. Additionally, carbetocin should not be used if a person has high blood pressure or cardiovascular problems.
The enamel margin of a composite resin preparation should be beveled in order to improve the appearance and expose the ends of the enamel rods for acid attack. The correct technique of enamel etching prior to placement of a composite resin restoration includes etching with 30%-50% phosphoric acid and rinsing thoroughly with water and drying with air only. In preparing a cavity for restoration with composite resin combined with an acid etch technique, all enamel cavosurface angles should be obtuse angles. Contraindications for composite include varnish and zinc oxide-eugenol.
As all techniques, cricoid pressure has indications, contraindications and side effects. It is associated with nausea/vomiting and it may cause esophageal rupture and also may make tracheal intubation and make ventilation difficult or impossible. Cricoid force greater than 40 N can compromise airway patency and make tracheal intubation difficult. Cricoid pressure may displace the esophagus, make ventilation with a facemask or with a laryngeal mask airway (LMA) more difficult, interfere with LMA placement and advancement of a tracheal tube and alter laryngeal visualization by a flexible bronchoscope.
Vaccine contraindications may prevent certain individuals from being vaccinated. In addition to not being immune, individuals in one of these groups may be at a greater risk of developing complications from infection because of their medical status, but they may still be protected if a large enough percentage of the population is immune. High levels of immunity in one age group can create herd immunity for other age groups. Vaccinating adults against pertussis reduces pertussis incidence in infants too young to be vaccinated, who are at the greatest risk of complications from the disease.
For hemodialysis patients, it is important to determine the treatment schedule. Dental treatment should be started on the day after hemodialysis due to several reasons: there is no accumulation of uremic toxins in the blood, and circulating heparin is absent. Treatment should not commence on the same day as hemodialysis as patients usually feel unwell and their blood is heparinized, which might cause excessive bleeding. For patients undergoing peritoneal dialysis, there are no contraindications to dental treatment except in cases of acute peritoneal infections, where elective procedure should be deferred.
The higher level of copper improved the setting reaction of amalgam, giving greater corrosion resistance and early strength after setting. Possible indications for amalgam are for load-bearing restorations in medium to large sized cavities in posterior teeth, and in core build-ups when a definitive restoration will be an indirect cast restoration such as a crown or bridge retainer. Contraindications for amalgam are if aesthetics are paramount to patient due to the colour of the material. Amalgams should be avoided if the patient has a history of sensitivity to mercury or other amalgam components.
Topical cyanoacrylate adhesives (closely related to super glue), have been used in combination with, or as an alternative to, sutures in wound closure. The adhesive remains liquid until exposed to water or water-containing substances/tissue, after which it cures (polymerizes) and forms a bond to the underlying surface. The tissue adhesive has been shown to act as a barrier to microbial penetration as long as the adhesive film remains intact. Limitations of tissue adhesives include contraindications to use near the eyes and a mild learning curve on correct usage.
First and foremost, the cat must be kept well hydrated with wet food/soups/broth/increased water intake. This keeps the urine dilute, reducing pain and inflammation, as well as encouraging urination to keep the bladder clear of debris thereby reducing the risk of a § mechanical blockage (dry food must therefore be avoided). Since the underlying process is inflammation of the bladder, one of the most frequent pharmacological treatments is to administer anti-inflammatory medication. NSAIDs such as meloxicam or robenacoxib are commonly prescribed to control this (provided there are no renal or gastric contraindications).
The IO site can be used for 24 hours and should be removed as soon as intravenous access has been gained. Prolonged use of an IO site, lasting longer than 24 hours, is associated with osteomyelitis (an infection in the bone).NIO IO deviceIntraosseous infusions have several contraindications, including sites that have known, or suspected fracture, appear to be infected, or where the skin is burned. Medical conditions that might also preclude the use of intraosseous infusion include osteopenia, osteopetrosis, and osteogenesis imperfecta as fractures are more likely to occur.
Epidemiological studies have shown that oral contraceptives that contain desogestrel can increase the risk of blood clots (venous thrombosis) by 1.5 to 2.4 times the risk of second-generation oral contraceptives. Second-generation oral contraceptives do not contain desogestrel. Hormones are released continuously from NuvaRing, thus peak and total estrogen and progestin doses are lower than with combined oral contraceptives, but what effect this has on the risk of blood clots has not been established. NuvaRing also has the cardiovascular contraindications associated with combined oral contraceptives, such as stroke and heart attack.
Tea tree oil has been promoted as a treatment for head lice; however, there is no clear evidence of its effectiveness. A 2012 review of head lice treatment recommended against the use of tea tree oil for children because it could cause skin irritation or allergic reactions, because of contraindications, and because of a lack of knowledge about the oil's safety and effectiveness. Other home remedies, such as putting vinegar, isopropyl alcohol, olive oil, mayonnaise, or melted butter under a shower cap, have been disproven. The CDC states that swimming has no effect on lice, and can decrease the effectiveness of some treatments.
It may be better than rocuronium in people without contraindications due to its faster onset of action and shorter duration of action. Suxamethonium is also commonly used as the sole muscle relaxant during electroconvulsive therapy, favoured for its short duration of action. Suxamethonium is quickly degraded by plasma butyrylcholinesterase and the duration of effect is usually in the range of a few minutes. When plasma levels of butyrylcholinesterase are greatly diminished or an atypical form is present (an otherwise harmless inherited disorder), paralysis may last much longer, as is the case in liver failure or in neonates.
She worked as a general practitioner in Sheffield, setting up a Family planning clinic, known as the 408 Clinic, in the city's east end. The clinic attracted controversy as it provided contraception to unmarried women. After moving to Glasgow she worked in the Family Planning Association advising women, particularly those from deprived areas, on sexual health, contraception and abortion. On a visit to Hong Kong, she witnessed the effectiveness of the contraceptive medroxyprogesterone acetate, and on her return to Glasgow, she reviewed the benefits and contraindications of the drug, and began offering it in her clinics.
Oclacitinib is not labeled for use in dogs younger than one due to reports of it causing demodicosis. It should also be avoided in dogs less than . Most of the other contraindications are avoiding cases where a potential side effect exacerbates a pre-existing condition: for example, because oclacitinib can cause lumps or tumors, it should not be used in dogs with cancer or a history of it; because it is an immune system suppressant, it should not be used in dogs with serious infections. Oclacitinib, by virtue of its low plasma protein binding, has little chance of reacting with other drugs.
Early treatment of an ectopic pregnancy with methotrexate is a viable alternative to surgical treatment which was developed in the 1980s."History, Diagnosis and Management of Ectopic Pregnancy" If administered early in the pregnancy, methotrexate terminates the growth of the developing embryo; this may cause an abortion, or the developing embryo may then be either resorbed by the woman's body or pass with a menstrual period. Contraindications include liver, kidney, or blood disease, as well as an ectopic embryonic mass > 3.5 cm. Also, it may lead to the inadvertent termination of an undetected intrauterine pregnancy, or severe abnormality in any surviving pregnancy.
Nolte, 2012 Electrophysial functional mapping, a tool used in both methods to verify the target nuclei, has come under scrutiny due to its associated risks of hemorrhages, dysarthria or tetanic contractions. Recently, susceptibility-weighted imaging, a type of MRI, has shown incredible power in its ability to distinguish these deep brain nuclei and is being used in DBS to reduce the overuse of EFM.Abosch, 2010 DBS is recommended to PD patients without important neuropsychiatric contraindications who suffer motor fluctuations and tremor badly controlled by medication, or to those who are intolerant to medication. DBS is effective in suppressing symptoms of PD, especially tremor.
No one has exclusive rights to the formula. Instead, "patent" refers to the standardization of the formula. In China, all Chinese patent medicines of the same name have the same proportions of ingredients, and are manufactured in accordance with the PRC Pharmacopoeia's monograph on that particular formula, which is mandated by Chinese law. Each monograph details the exact herbal ingredients that make up the patent formula, usually accompanied by the specific tests that should be used for correct herb identification, such as thin layer chromatography (TLC) or high performance liquid chromatography (HPLC), the percentage of each ingredient, and specific cautions and contraindications.
This drug is contraindicated in people with cancers that secrete catecholamines (for example epinephrine), such as phaeochromocytoma or paraganglioma, because as a COMT inhibitor it blocks catecholamine degradation. Other contraindications are a history of neuroleptic malignant syndrome (NMS) or non-traumatic rhabdomyolysis, and combination with monoamine oxidase inhibitors that are not used as antiparkinsonians, because of possible drug interactions. NMS and associated rhabdomyolysis have been rarely observed under the older COMT inhibitors tolcapone and entacapone. This typically occurs shortly after the beginning of a COMT inhibitor add-on therapy when the levodopa dose has been reduced, or after discontinuation of a COMT inhibitor.
Its third indication is to assess left ventricular function (ejection fraction) in patients thought to have heart disease. No contraindications are known for use of Tc-99m tetrofosmin, but care should be taken to constantly monitor the cardiac function in patients with known or suspected coronary artery disease. Patients should be encouraged to void their bladders as soon as the images are gathered, and as often as possible after the tests to decrease their radiation doses, since the majority of elimination is renal. The recommended dose of Tc-99m tetrofosmin is between 5 and 33 millicuries (185-1221 megabecquerels).
Requests have been raised in scientific literature for an improved Cardiac contractility modulation algorithm which would allow the therapy to be delivered independently from any atrial signal. A pioneering study had shown that an improved Cardiac contractility modulation algorithm could make the therapy an effective treatment for patients with persistent atrial fibrillation. Following these study results the new generation was developed and can now offer Cardiac contractility modulation therapy also for patients with atrial fibrillation. Other irregular rhythms, including frequent premature ventricular contractions (ventricular extra systoles) or a distinct signal transduction disorder in the heart (untreated AV block of more than 300 ms), may represent contraindications.
Several DTC ads have faced criticism or FDA warnings over containing depictions of activities that are part of a prescription's contraindications, such as an advertisement for the blood thinner Xarelto which featured scenes of a patient spokesperson among motorcycles (despite a disclaimer stating that the spokespatient had to stop riding her motorcycle whilst taking the medication), and a print ad for the Factor IX treatment Idelvion containing an image of a soccer player (with the FDA warning that soccer was a "moderate to dangerous high-risk activity for hemophilic patients", and that the ad falsely implied patients could engage in such activity without consequences).
Under the regulations of the Food and Drug Administration (FDA), direct-to-consumer "product claim" advertisements for a prescription medication must include information on their major side effects and contraindications in the main body, with a "fair balance" in its coverage of benefits to risks. Unless they are given "adequate provision" via a variety of different outlets, ads must also include a "brief summary" of all risks associated with the medication. In print ads within magazines, this summary is typically given on a second page. Print ads must contain a standard notice that instructs patients to report negative side effects to the FDA's MedWatch program.
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS). Information within the BNF includes indication(s), contraindications, side effects, doses, legal classification, names and prices of available proprietary and generic formulations, and any other notable points. Though it is a national formulary, it nevertheless also includes entries for some medicines which are not available under the NHS, and must be prescribed and/or purchased privately. A symbol clearly denotes such drugs in their entry.
While polypharmacy is typically regarded as undesirable, prescription of multiple medications can be appropriate and therapeutically beneficial in some circumstances. “Appropriate polypharmacy” is described as prescribing for complex or multiple conditions in such a way that necessary medicines are used according to best evidence to preserve safety and well-being. Polypharmacy is clinically indicated in some conditions, including diabetes mellitus, but should be discontinued when evidence of benefit from the prescribed drugs no longer outweighs potential for harm (described below in Contraindications). Often certain medications can interact with others in a positive way specifically intended when prescribed together, to achieve a greater effect than any of the single agents alone.
In the United States, the Advisory Committee on Immunization Practices makes scientific recommendations regarding vaccines and vaccination schedules that the federal government, state governments, and private health insurance companies generally follow. See Vaccination schedule for the schedule recommended in the United States. All 50 states in the U.S. mandate immunizations for children in order to enroll in public school, but various exemptions are available depending on the state. All states have exemptions for people who have medical contraindications to vaccines, and all states except for California, Maine, Mississippi, New York, and West Virginia allow religious exemptions, while sixteen states allow parents to cite personal, conscientious, philosophical, or other objections.
The rationale for radioactive iodine is that it accumulates in the thyroid and irradiates the gland with its beta and gamma radiations, about 90% of the total radiation being emitted by the beta (electron) particles. The most common method of iodine-131 treatment is to administer a specified amount in microcuries per gram of thyroid gland based on palpation or radiodiagnostic imaging of the gland over 24 hours. Patients who receive the therapy must be monitored regularly with thyroid blood tests to ensure they are treated with thyroid hormone before they become symptomatically hypothyroid. Contraindications to RAI are pregnancy (absolute), ophthalmopathy (relative; it can aggravate thyroid eye disease), or solitary nodules.
Contraindications of progesterone include hypersensitivity to progesterone or progestogens, prevention of cardiovascular disease (a Black Box warning), thrombophlebitis, thromboembolic disorder, cerebral hemorrhage, impaired liver function or disease, breast cancer, reproductive organ cancers, undiagnosed vaginal bleeding, missed menstruations, miscarriage, or a history of these conditions. Progesterone should be used with caution in people with conditions that may be adversely affected by fluid retention such as epilepsy, migraine headaches, asthma, cardiac dysfunction, and renal dysfunction. It should also be used with caution in patients with anemia, diabetes mellitus, a history of depression, previous ectopic pregnancy, venereal disease, and unresolved abnormal Pap smear. Use of progesterone is not recommended during pregnancy and breastfeeding.
The lack of an adequate venous conduit is a relative contraindication to bypass surgery, and depending on the area of disease, alternatives may be used. Medical conditions such as ischemic heart disease or chronic obstructive pulmonary disease that increase the risk of surgery are also relative contraindications. For coronary and peripheral vascular disease, lack of "runoff" to the distal area is also a contraindication because a vascular bypass around one diseased artery to another diseased area does not solve the vascular problem. If a patient is deemed to be too high-risk to undergo a bypass, he or she may be a candidate for angioplasty or stenting of the relevant vessel.
The yoga scholar Andrea Jain describes these claims of Iyengar's in terms of "elaborating and fortifying his yoga brand" and "mass-marketing", calling Iyengar's 1966 book Light on Yoga "arguably the most significant event in the process of elaborating the brand". The yoga teacher Bernie Gourley notes that the book neither describes contraindications systematically, nor provides evidence for the claimed benefits. Jain suggests that "Its biomedical dialect was attractive to many." For example, in the book, Iyengar claims that the asanas of the Eka Pada Sirsasana cycle The history of such claims was reviewed by William J. Broad in his 2012 book The Science of Yoga.
The body of the policy statement notes and cites literature indicating that, in addition to the importance of mother's milk, the manner of the food delivery has implications: that "breastfed infants self-regulate intake volume", whereas bottle-fed infants receiving expressed breast milk or formula have "increased bottle emptying, poorer self-regulation, and excessive weight gain in late infancy", and that such early practice of self-regulation correlate with adult patterns of weight gain (ibid.). The AAP policy notes that "[m]edical contraindications to breastfeeding are rare". The transmission of some viral diseases through breastfeeding is reportedly preventable, e.g., by expressing breast milk and subjecting it to Holder pasteurization.
Light therapy is a mood altering treatment, and just as with drug treatments, there is a possibility of triggering a manic state from a depressive state, causing anxiety and other side effects. While these side effects are usually controllable, it is recommended that patients undertake light therapy under the supervision of an experienced clinician, rather than attempting to self-medicate. Contraindications to light therapy for seasonal affective disorder include conditions that might render the eyes more vulnerable to phototoxicity, tendency toward mania, photosensitive skin conditions, or use of a photosensitizing herb (such as St. John's wort) or medication. Patients with porphyria should avoid most forms of light therapy.
The treatment for acute hypercapnic respiratory failure depends on the underlying cause, but may include medications and mechanical respiratory support. In those without contraindications, non-invasive ventilation (NIV) is often used in preference to invasive mechanical ventilation. In the past, the drug doxapram (a respiratory stimulant), was used for hypercapnia in acute exacerbation of chronic obstructive pulmonary disease but there is little evidence to support its use compared to NIV, and it does not feature in recent professional guidelines. Very severe respiratory failure, in which hypercapnia may also be present, is often treated with extracorporeal membrane oxygenation (ECMO), in which oxygen is added to and carbon dioxide removed directly from the blood.
Repeated doses of activated charcoal have been proposed to be beneficial in cases of salicylate poisoning, especially in ingestion of enteric coated and extended release salicylic acid formulations which are able to remain in the gastrointestinal (GI) tract for longer periods of time. Repeated doses of activated charcoal are also useful to re-adsorb salicylates in the GI tract that may have desorbed from the previous administration of activated charcoal. The initial dose of activated charcoal is most useful if given within 2 hours of initial ingestion. Contraindications to the use of activated charcoal include altered mental status (due to the risk of aspiration), GI bleeding (often due to salicylates) or poor gastric motility.
In general, the simultaneous use of multiple drugs should be carefully monitored by a qualified individual such as board certified and licensed medical doctor, either an MD or DO. Close association between prescribing physicians and pharmacies, along with the computerization of prescriptions and patients' medical histories, aim to avoid the occurrence of dangerous drug interactions. Lists of contraindications for a drug are usually provided with it, either in monographs, package inserts (accompanying prescribed medications), or in warning labels (for OTC drugs). CDI/MDI might also be avoided by physicians requiring their patients to return any unused prescriptions. Patients should ask their doctors and pharmacists if there are any interactions between the drugs they are taking.
Alveoloplasty is contraindicated in situations whereby vital structures such as nerve bundle, blood vessel and/or vital tooth will be harmed during removal of bone structure. Nerve injury is unfavourable as there will be a risk of complications such as paraesthesia, neuropathic pain, allodynia and others. In addition to this, if there is existing diminished volume or atypical architecture of bone; alveoloplasty is not a recommended procedure as well. Some important points to be included as contraindications of alveoloplasty consist of individuals who have undergone head and neck radiation therapy or individuals with medical condition which will result in certain medical complications such as uncontrolled or excessive bleeding, poor healing response or immunocompromised.
The time-course of an immune response begins with the initial pathogen encounter, (or initial vaccination) and leads to the formation and maintenance of active immunological memory. Vaccine-naive is a lack of immunity, or immunologic memory, to a disease because the person has not been vaccinated. There are a variety of reasons why a person may not have received a vaccination, including contraindications due to preexisting medical conditions, lack of resources, previous vaccination failure, religious beliefs, personal beliefs, fear of side-effects, phobias to needles, lack of information, vaccine shortages, physician knowledge and beliefs, social pressure, and natural resistance.Wallace, H. Shortages require practices to take extra measures to keep patients up-to-date on vaccines: Calling the shots.
The rule regarding patients providing their own medications does not apply to the "drugs" oral glucose, activated charcoal, aspirin, or oxygen as the first two are not pharmacologically active; aspirin and oxygen have very few contraindications; they are not prescription controlled (except medical oxygen, which is not prescribed per patient, but rather per institution); and none are typically carried by patients. Thus, the OEC technician typically has access to these four interventions and may assist in their administration as warranted. Technicians must attend annual OEC refresher courses in order to maintain their certification. The OEC refreshers cover 1/3 of the OEC curriculum each year which cycles through the entire course every three years.
In the UK, official guidelines state that women should be permitted and encouraged to have one asymptomatic birth partner present with them during their labour and birth. There is no evidence regarding if there is vaginal shedding of the virus, so the mode of birth (vaginal or caesarean) should be discussed with the woman in labour and take into consideration her preferences if there are no other contraindications. If a patient has a scheduled elective caesarean birth or a planned induction of labour, an individual assessment should consider whether it is safe to delay the procedure to minimise the risk of infecting others. Products of conception, such as the placenta, amnion etc.
Chloroquine was initially recommended by Indian, Chinese, South Korean and Italian health authorities for the treatment of COVID‑19, although these agencies and the US CDC noted contraindications for people with heart disease or diabetes. In February 2020, both drugs were shown to effectively reduce COVID‑19 illness, but a further study concluded that hydroxychloroquine was more potent than chloroquine and had a more tolerable safety profile. On 18 March, the WHO announced that chloroquine and the related hydroxychloroquine would be among the four drugs studied as part of the Solidarity clinical trial. Hydroxychloroquine and chloroquine have numerous, potentially serious, side effects, such as retinopathy, hypoglycemia, or life-threatening arrhythmia and cardiomyopathy.
However, under the direction of an expert, participation in physical activity can be safe and has been proven beneficial for persons with MS. Research has supported the rehabilitative role of physical activity in improving muscle power, mobility, mood, bowel health, general conditioning and quality of life. The effectiveness of interventions, including exercise, specifically for the prevention of falls in people with MS is uncertain, while there is some evidence of an effect on balance function and mobility. Depending on the person, activities may include resistance training, walking, swimming, yoga, tai chi, and others. Determining an appropriate and safe exercise program is challenging and must be carefully individualized to each person being sure to account for all contraindications and precautions.
Physical screening standards which take into account anticipated work demands are commonly used by commercial and military divers, and detailed lists of physical contraindications to diving have been published. These standards can vary widely, but the need for physical screening is generally accepted. Behavioral problems may be more important than physical problems because 'no amount of physical screening can protect a diver from his own stupidity' and 'the majority of diving accidents are caused by poor judgment or inattention to the basic rules of diving safety... ' Mental fitness may be at least as important as physical fitness for divers. and maturity and responsibility should be evaluated as carefully as physical health and fitness.
In essence, ultrasonic waves are focused on specific areas of the prostate to eliminate the prostate cancer, with minimal risks of affecting other tissue or organs. Temperatures at the focal point of the sound waves can exceed 100 °C (212 °F). However, many studies of HIFU were performed by manufacturers of HIFU devices, or members of manufacturers' advisory panels. Contraindications to HIFU for prostate cancer include a prostate volume larger than 40 grams, which can prevent targeted HIFU waves from reaching the anterior and anterobasal regions of the prostate, anatomic or pathologic conditions that may interfere with the introduction or displacement of the HIFU probe into the rectum, and high- volume calcification within the prostate, which can lead to HIFU scattering and transmission impairment.
There is limited evidence on the use of chloroquine in people with COVID-19. Chloroquine has been approved by Chinese, South Korean and Italian health authorities for the experimental treatment of COVID-19. These agencies noted contraindications for people with heart disease or diabetes. However, use of chloroquine is only recommended in the setting of an approved trial or under the details outlined by Monitored Emergency Use of Unregistered Interventions. On 1 April 2020, the European Medicines Agency (EMA) issued guidance that chloroquine and hydroxychloroquine are only to be used in clinical trials or emergency use programs. On 29 May 2020, the EMA stated that patients already taking chloroquine for unrelated conditions, should continue to do so, always under the supervision of their doctor.
Direct-to-consumer advertising (DTCA) refers to the marketing and advertising of pharmaceutical products directly to consumers as patients, as opposed to specifically targeting health professionals. The term is synonymous primarily with the advertising of prescription medicines via mass media platforms—most commonly on television and in magazines, but also via online platforms. Direct-to-consumer advertising is only completely legal in New Zealand and the United States, but are subject to regulations regarding the balanced disclosure of a prescription's benefits in comparison to its risks (including but not limited to side effects and contraindications), among other factors. Regulations regarding DTCA are typically applied to advertising materials that describe a prescription's indications and benefits, and may be more lenient to advertising materials which do not discuss uses.
Anatomical considerations may also dictate preference for surgical or non- surgical approaches. For instance trismus, a bulky tongue, limited extension of the neck, prominent teeth, torus mandibularis (a bony growth on the mandible) or limited width of the mandible would all be relative contraindications to surgery. Tumour related considerations include invasion of the mandible, base of skull and extensive involvement of the larynx or more than half of the base of tongue. Technical considerations in offering surgery as a primary modality include the presumed ability to achieve adequate margins in the resected specimen and the degree of resulting defect, since close or positive margins are likely to result in subsequent adjuvant therapy to achieve disease control, with resultant increased morbidity.
Ulcerative colitis and familial adenomatous polyposis are the two main health conditions that lead to removal of the entire colon (large intestine) and rectum, which leads to the need for an ileostomy. Candidates for BCIR include: people who are dissatisfied with the results of an alternate procedure (whether a conventional Brooke ileostomy or another procedure); patients with a malfunctioning/failed Kock pouch or IPAA/J-pouch; and individuals with poor internal/external anal sphincter control who either elect not to have the J-pouch (IPAA) or are not a good candidate for IPAA. There are, however, some contraindications for having the BCIR surgery. BCIR is not for people who have or need a colostomy, people with [active] Crohn's disease, mesenteric desmoids, obesity, advanced age, or poor motivation.
Various studies have shown that insertion and use of the standard tracheal tube is easy, providing a clear airway in the majority of cases. Comparative studies indicate that the standard laryngeal tube is generally as effective as the laryngeal mask airway, while some studies indicate that the Pro-seal laryngeal mask may be more effective than the standard laryngeal tube under controlled ventilation conditions in general anaesthesia. The indications and contraindications for use of the laryngeal tube are similar to those of the laryngeal mask airway and include the use in general anaesthesia for minor surgical operations. Several studies describe the usefulness of the device in securing a difficult airway, even in cases where insertion of the laryngeal mask had failed.
Contraindications include prior treatment (within the past 5–6 weeks, depending on the dose) with MAOIs such as phenelzine and tranylcypromine, due to the potential for serotonin syndrome. Its use should also be avoided in those with known hypersensitivities to fluoxetine or any of the other ingredients in the formulation used. Its use in those concurrently receiving pimozide or thioridazine is also advised against. In some cases, use of dextromethorphan-containing cold and cough medications with fluoxetine is advised against, due to fluoxetine increasing serotonin levels, as well as the fact that fluoxetine is a cytochrome P450 2D6 inhibitor, which causes dextromethorphan to not be metabolized at a normal rate, thus increasing the risk of serotonin syndrome and other potential side effects of dextromethorphan.
In 2017, a review of watchful waiting vs the early birth strategy was conducted to ascertain which was associated with a lower overall risk. Focusing on the 24–37-week range, the review analysed twelve randomised controlled trials from the "Cochrane Pregnancy and Childbirth's Trials Register", concluding that "In women with PPROM before 37 weeks' gestation with no contraindications to continuing the pregnancy, a policy of expectant management with careful monitoring was associated with better outcomes for the mother and baby." There is believed to be a correlation between volume of amniotic fluid retained and neonatal outcomes before 26 weeks' gestation. Amniotic fluid levels are an important consideration when debating expectant management vs clinical intervention, as low levels, or oligohydramnios, can result in lung and limb abnormalities.
Using a catheter that is directed through the blood vessels in the arm or leg up to the brain, the interventionalist can remove the thrombus or deliver drugs to dissolve the thrombus. These procedures are referred to as mechanical thrombectomy or thrombolysis, and several factors are considered before the procedure is completed. People who may be eligible for endovascular treatment have a large vessel occlusion, which means the thrombus is in an artery that is large enough to reach and there are no contraindications such as, a hemorrhagic stroke (bleeding in the brain), greater than six hours since onset of symptoms, or greater than 24 hours in special cases. Hospitals with comprehensive stroke centers are equipped to treat patients with endovascular care.
Because the risks of warfarin – which is used to treat blood clots – in a relatively young and otherwise healthy population are low, while the risk of adverse physical and psychological outcomes for untreated transgender patients is high, prothrombotic mutations (such as factor V Leiden, antithrombin III, and protein C or S deficiency) are not absolute contraindications for hormonal therapy. A 2018 cohort study of 2842 transfeminine individuals in the United States treated with a mean follow-up of 4.0 years observed an increased risk of VTE, stroke, and heart attack relative to a cisgender reference population. The estrogens used included oral estradiol (1 to 10 mg/day) and other estrogen formulations. Other medications such as antiandrogens like spironolactone were also used.
The Montreal Criteria are a set of criteria deemed to be required for the ethical execution of the uterine transplant in humans. These findings were presented at the International Federation of Gynecology and Obstetrics' 20th World Congress in Rome in October 2012. In 2013 an update to "The Montreal Criteria for the Ethical Feasibility of Uterine Transplantation" was published in Fertility and Sterility and has been proposed as the international standard for the ethical execution of the procedure. The criteria set conditions for the recipient, the donor, and the health care team, specifically: # The recipient is a cisgender female with no medical contraindications to transplantation, has uterine disease that has failed other therapy, and has "a personal or legal contraindication" to other options (surrogacy, adoption).
A nail technician will often complete a consultation with the client to check for any signs of skin problems, deformities or nail disease before treatment and give clients advice about looking after their hands and nails, and recommend nail care products. Training to become a nail technician involves doing a professional course that normally takes at least a year to complete. Courses will more than likely cover anatomy and physiology of the nails, hands, arms, feet and legs, contraindications that may arise, identifying diseases and disorders, proper sanitation and sterilizing techniques, how to perform nail services safely, gel polish application, liquid and powder enhancements and hard gel enhancements. The work itself tends to take place in a beauty salon although some nail technicians will make house calls to clients.
Oxford: Oxford University Press There is evidence and rationale to support giving low doses of benzodiazepines or otherwise low doses of general anesthetics, which induce sedation but not anesthesia, to patients to reduce adverse effects of ECT. While there are no absolute contraindications for ECT, there is increased risk for patients who have unstable or severe cardiovascular conditions or aneurysms; who have recently had a stroke; who have increased intracranial pressure (for instance, due to a solid brain tumor), or who have severe pulmonary conditions, or who are generally at high risk for receiving anesthesia. In adolescents, ECT is highly efficient for several psychiatric disorders, with few and relatively benign adverse effects.Neera Ghaziuddin, Garry Walter (eds.): Electroconvulsive Therapy in Children and Adolescents, Oxford University Press, 2013, , p. 161-280.
The Advisory Committee on Immunization Practices makes scientific recommendations which are generally followed by the federal government, state governments, and private health insurance companies. All 50 states in the U.S. mandate immunizations for children in order to enroll in public school, but various exemptions are available depending on the state. All states have exemptions for people who have medical contraindications to vaccines, and all states except for California, Maine, Mississippi, New York, and West Virginia allow religious exemptions, while sixteen states allow parents to cite personal, conscientious, philosophical, or other objections. An increasing number of parents are using religious and philosophical exemptions: researchers have cited this increased use of exemptions as contributing to loss of herd immunity within these communities, and hence an increasing number of disease outbreaks.
There is no reliable way to determine who will have an intracranial bleed post-treatment versus who will not. In those with findings of savable tissue on medical imaging between 4.5 hours and 9 hours or who wake up with a stroke, alteplase results in some benefit. Its use is endorsed by the American Heart Association, the American College of Emergency Physicians and the American Academy of Neurology as the recommended treatment for acute stroke within three hours of onset of symptoms as long as there are no other contraindications (such as abnormal lab values, high blood pressure, or recent surgery). This position for tPA is based upon the findings of two studies by one group of investigators which showed that tPA improves the chances for a good neurological outcome.
Giving an influenza vaccination The influenza vaccine is recommended by the World Health Organization (WHO) for high-risk groups, such as pregnant women, children aged less than five years, the elderly, health care workers, and people who have chronic illnesses such as HIV/AIDS, asthma, diabetes, heart disease, or are immunocompromised among others. The United States Centers for Disease Control and Prevention (CDC) recommends the influenza vaccine for those aged six months or older who do not have contraindications. In healthy adults it is modestly effective in decreasing the amount of influenza-like symptoms in a population. In healthy children over the age of two years, the vaccine reduces the chances of getting influenza by around two-thirds, while it has not been well studied in children under two years.
The contraindications for mastopexy are few: aspirin use, tobacco smoking, diabetes, and obesity are medical and health conditions associated with increased incidences of nipple necrosis. In resolving the perceived ptosis of a woman with encapsulated breast implants, the surgeon determines her suitability for a breast lift procedure after explantation, which facilitates assessment of the true degree of ptosis present in the explanted breasts; likewise the assessment of the effects of a combined breast-lift and revision-augmentation procedure, featuring the removal and the replacement of breast implants. For the woman who is at high risk for developing breast cancer (primary or recurrent), the mastopexy might alter the histologic architecture of the breasts, which tissue change might interfere with the accurate MRI detection and subsequent treatment of cancer; the risks and benefits will be discussed in that setting.
Massive PE causing hemodynamic instability (shock and/or low blood pressure, defined as a systolic blood pressure <90 mmHg or a pressure drop of 40 mmHg for >15 min if not caused by new-onset arrhythmia, hypovolemia or sepsis) is an indication for thrombolysis, the enzymatic destruction of the clot with medication. In this situation, it is the best available treatment in those without contraindications and is supported by clinical guidelines. It is also recommended in those in cardiac arrest with a known PE. Catheter-directed thrombolysis (CDT) is a new technique found to be relatively safe and effective for massive PEs. This involves accessing the venous system by placing a catheter into a vein in the groin and guiding it through the veins by using fluoroscopic imaging until it is located next to the PE in the lung circulation.
In the article he explained the technique he had developed in order to be able to inject the anesthetics in the lumbar region, leaving the spinal canal untouched and without the need to reach complete anesthesia. The article explained how Pagés, who had frequently performed spinal anesthesias, developed the idea of injecting the anesthetics through the lumbar space between the 4th and 5th vertebrae, described 43 operations using this technique, provided details on each step and advised on the right dose of anaesthetics (twice as much as was previously recommended in similar techniques). It also explained the effects of gradual insensibility and motor paralysis, the indications and contraindications and concluded recommending the use of this technique for surgical interventions. The technique was widely put into practice in the following months during the Spanish campaign in the Rif.
Suspicion of fetal infections, such as rubella and toxoplasmosis, as well as the need to supply medicine or blood transfusions to the fetus are indications for the use of PUBS. Due to its invasive nature, the contraindications of PUBS, reasons to not undergo the procedure, must be taken into account in order to ensure the safety of the fetus and the mother. During the first 18 weeks of pregnancy, the umbilical vein from which the blood sample is taken is not very stable, which could lead to excessive bleeding; therefore, PUBS is contraindicated in any fetus under the age of 18 weeks old. While blood gas levels and pH values are able to give parents and medical professionals a snapshot of fetal status, these fetuses can be monitored with less invasive procedures and equipment, such as ultrasounds, cardiotocography, or maternal blood tests.
Over the past several years assessment of small bowel diseases was performed by Barium follow through, or upper and lower gastrointestinal series, that provided plan film of bowel loop lumen, thanks to the swallowing or instillation of radiopaque agents mixed with water or other neutral contrast media. Gastrointestinal series allow to depict lumen caliber, gross mucosal alterations and wide fistulous tract, but were poorly diagnostic for submucosal or extraluminal features. CT scan instead provides cross sectional and multiplanar images of intraluminal and extra-mucosal, extra-luminal or even extra-enteric features, but costing higher radiation dose. The spread of MR technique has revolutionized the diagnostic imaging of the small bowel loop, restricting CT scan to particular situations, such as emergency or MR contraindications like patients with pacemaker implant, recently implanted vascular/bilious stent or other ferromagnetic prosthesis/devices.
The psychic driving procedure was a chronological precursor to Cameron's depatterning, the latter involving massive doses of electroconvulsive therapy (ECT) combined with similarly large doses of psychedelic drugs (such as LSD). The intent was to break down the subject's personality—theoretically psychic driving could then be used with some efficacy in establishing a new personality. In Cameron's depatterning, the ECT would often continue to be administered despite the manifestation of convulsive fits, which were consensually considered to be contraindications to normal and safe ECT procedure. Such biologically and psychologically devastating procedures, adopted internationally by the psychiatric establishment, were largely abolished by the time the CIA was brought before a Senate Hearing (1977)Transcript of the 1977 Senate Hearing can be found here , here or here for its involvement and funding of Cameron's experimental activities--as part of the MKULTRA program.
Therefore, is indicated in cases of a suspected central suppression scotoma as it can be used to detect where the lights may not be appreciated from the eye with the scotoma though in some cases of minimal deviation in the eye as demonstrated in a microtropic deviation a normal response of 4 lights may be reported. Though it can be used in these patients to prove the presence of peripheral fusion and that they have bi-foveal fixation. Other indications for the test include establishing an individual's dominant eye dominant eye compared to the other and when evaluating reduced monocular visual acuity which shows no improve on pinhole testing. Whilst there are no contraindications of the W4LT there needs to be caution in interpreting the results of individuals with BSV in natural conditions as they may show a diplopic response under the dissociation of the test.
The Advisory Committee on Immunization Practices makes scientific recommendations which are generally followed by the federal government, state governments, and private health insurance companies, including making recommendations for the vaccination schedule used in the United States. All 50 states in the U.S. mandate immunizations for children in order to enroll in public school, but the specific vaccines required differ from state to state and various exemptions are available depending on the state. All states have exemptions for people who have medical contraindications to vaccines, and all states except for California, Maine, Mississippi, New York, and West Virginia allow religious exemptions, while sixteen states allow parents to cite personal, conscientious, philosophical, or other objections. An increasing number of parents are using religious and philosophical exemptions: researchers have cited this increased use of exemptions as contributing to loss of herd immunity within these communities, and hence an increasing number of disease outbreaks.
The primary purpose of NITAG is to provide technical resources, supplying guidance and recommendations to national policy makers and programme managers to enable them to make evidence-based immunization related policy and program decisions. This may also include vaccination schedules regarding appropriate timing, dosage, and contraindications of vaccines. To ensure that the government gives proper attention to NITAG recommendations, NITAG usually report to high level officials of the Ministry of Health. NITAG are considered to be functional when they meet six defined process indicators agreed upon by the World Health Organization (WHO), which are: # having a legislative or administrative basis, # having formal terms of reference, # having at least five areas of expertise represented among its membership, # having at least one meeting per year, # distribution of the agenda and background documents at least one week prior to meetings, and # having mandatory disclosure of conflict of interests.
In the European Union, sertindole was approved and marketed in 19 countries from 1996, but its marketing authorization was suspended by the European Medicines Agency in 1998EU CHMP recommends lifting ban on atypical antipsychotic Serdolect (sertindole) - National electronic Library for Medicines, NHS and the drug was withdrawn from the market. In 2002, based on new data, the EMA's CHMP suggested that Sertindole could be reintroduced for restricted use in clinical trials, with strong safeguards including extensive contraindications and warnings for patients at risk of cardiac dysrhythmias, a recommended reduction in maximum dose from 24 mg to 20 mg in all but exceptional cases, and extensive ECG monitoring requirement before and during treatment.COMMITTEE FOR PROPRIETARY MEDICINAL PRODUCTS OPINION FOLLOWING AN ARTICLE 36 REFERRAL: SERTINDOLE - European Medicines Agency, 13 Sep 2002Restricted re-introduction of the atypical antipsychotic sertindole (Serdolect) - MHRA, 2002 , sertindole is authorized in several states of the European Union.
Each test has its own indications and contraindications, but in a simplified fashion, how much a test is indicated for an individual depends largely on its net benefit for that individual, which largely depends on the absolute difference between pre- and post-test probability of conditions (such as diseases) that the test is expected to achieve. Additional factors that influence a decision whether a medical test should be performed or not include: cost of the test, time taken for the test or other practical or administrative aspects. The possible benefits of a diagnostic test may also be weighed against the costs of unnecessary tests and resulting unnecessary follow-up and possibly even unnecessary treatment of incidental findings. Also, even if not beneficial for the individual being tested, the results may be useful for the establishment of statistics in order to improve health care for other individuals.
It found that 41% of these pages were updated within two weeks after the warning, 23% were updated more than two weeks later, and the remaining 36% had not been updated to include the warning as of more than 1 year later as of January 2014. A 2014 study in the Journal of the American Pharmacists Association examined 19 Wikipedia articles about herbal supplements, and concluded that all of these articles contained information about their "therapeutic uses and adverse effects", but also concluded that "several lacked information on drug interactions, pregnancy, and contraindications". The study's authors therefore recommended that patients not rely solely on Wikipedia as a source for information about the herbal supplements in question. Another study published in 2014 in PLOS ONE found that Wikipedia's information about pharmacology was 99.7% accurate when compared to a pharmacology textbook, and that the completeness of such information on Wikipedia was 83.8%.
Only 4.46% of the recreational diving fatalities in a 1997 study were attributable to a single contributory cause. The remaining fatalities probably arose as a result of a progressive sequence of events involving two or more procedural errors or equipment failures, and since procedural errors are generally avoidable by a well-trained, intelligent and alert diver, working in an organised structure, and not under excessive stress, it was concluded that the low accident rate in professional scuba diving is due to this factor. The study also concluded that it would be impossible to completely eliminate all minor contraindications of scuba diving, as this would result in overwhelming bureaucracy and bring all diving to a halt. Human factors in diving equipment design is the influence of the interaction between the diver and the equipment on the design of the equipment on which the diver relies to stay alive and in reasonable comfort, and to perform the planned tasks during a dive.
Other contraindications include the administration of hydroxyzine alongside depressants and other compounds which affect the central nervous system; if absolutely necessary, it should only be administered concomitantly in small doses. If administered in small doses with other substances, such as mentioned, then patients should refrain from using dangerous machinery, motor vehicles or any other practice requiring absolute concentration, in accordance with safety law. Studies have also been conducted which show that long-term prescription of hydroxyzine can lead to tardive dyskinesia after years of use, but effects related to dyskinesia have also anecdotally been reported after periods of 7.5 months, such as continual head rolling, lip licking and other forms of athetoid movement. In certain cases, elderly patients' previous interactions with phenothiazine derivatives or pre-existing neuroleptic treatment may have had some contribution towards dyskinesia at the administration of hydroxyzine due to hypersensitivity caused due to the prolonged treatment, and therefore some contraindication is given to the short-term administration of hydroxyzine to those with previous phenothiazine use.
Related CBS news item 19 November 2004. Between January 2003 and November 2005, a large randomized-controlled "Sibutramine Cardiovascular OUTcomes" (SCOUT) study with 10,742 patients examined whether or not sibutramine administered within a weight management program reduces the risk for cardiovascular complications in people at high risk for heart disease and concluded that use of silbutramine had a RR 1.16 for the primary outcome (composit of nonfatal MI, nonfatal CVA, cardiac arrest, and CV death). In a dissenting article, "Sibutramine: gone, but not forgotten", David Haslam (chairman of the National Obesity Forum) says that the SCOUT study is flawed as it only covered high-risk patients and did not consider obese patients who do not have cardiovascular complications or similar contraindications On January 21, 2010, the European Medicines Agency recommended suspension of marketing authorizations for sibutramine based on the SCOUT study results. In August 2010 the FDA added a new contraindication for patients over 65 years of age due to the fact that clinical studies of sibutramine did not include sufficient numbers of such patients.

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