104 Sentences With "chloral hydrate" | Random Sentence Generator

Loaded on booze, morphine, chloral hydrate, and vitamin B12, Williams crawled into the back seat, wrapped a blanket around himself, and laid down.

In retrospect, opting to stick with his liquor/morphine/chloral hydrate/vitamin B12 cocktail might have been the best move for his legacy, if not for his health.

Recently discovered letters suggest that Lincoln may have been taking too much chloral hydrate for sleep problems, which could account for some of her mental problems, Baker said.

Dressed in a Japanese kimono she bought on a bucket-list trip she took after being diagnosed in 2013, she swallowed a combination of morphine, pentobarbital and chloral hydrate prescribed by her doctor at 6:45 p.m.

Acetylglycinamide chloral hydrate is a hypnotic/sedative. It is a combination of acetylglycinamide and chloral hydrate.

Deuterochloroform can be prepared by the reaction of sodium deuteroxide with chloral hydrate.

Petrichloral (Pentaerythritol chloral) is a sedative and hypnotic chloral hydrate prodrug. It is a Schedule IV drug in the USA.

In 1977 she married Wayne Arthur Garland. In 1979, Smith committed suicide by swallowing chloral hydrate and paracetamol with salicylic acid.

Other relatives of ethanol with similar effects include chloral hydrate, paraldehyde, and many volatile and inhalational anesthetics (e.g., chloroform, diethyl ether, and isoflurane).

Tyndall died in 1940 at the age of 95. She outlived John by 47 years and throughout their time together, they had no children. John died from being accidentally given the wrong amount of medicine by Tyndall, which caused him to overdose on chloral hydrate. John had been using chloral hydrate to treat his insomnia for some time before the incident.

Some, such as sodium pentobarbitone, can kill animals humanely, but others such as chloral hydrate, methylated spirits, and nicotine-based poisons have been condemned by veterinarians.

She discovers that the victim, whose last meal had been pizza, was incapacitated with chloral hydrate. She returns to the motel room and orders a pizza, but Mulder soon appears and sends her back to autopsy another body. She leaves him just as her food is delivered. When she finds that the second victim had also ingested chloral hydrate in a pizza, she realizes Mulder is in danger and returns to the motel room.

The drug has been off the market and unavailable for decades. This combination anesthetic agent contains 42.5 mg chloral hydrate, 21.2 mg magnesium sulfate and 8.86 mg pentobarbital per milliliter.

The Swiss memorial to John Tyndall, with the Aletsch Glacier in the background Tyndall's grave in St Bartholomew's churchyard, Haslemere, Surrey U.K. In his last years Tyndall often took chloral hydrate to treat his insomnia. When bedridden and ailing, he died from an accidental overdoseIn late years he was taking magnesia for dyspepsia and chloral hydrate for insomnia. His wife, who administered the drugs, accidentally gave him none of the former and a lethal overdose of the latter. A newspaper report of Mrs.

Side effects of chloral hydrate include vomiting, nausea, gastric irritation, delirium, disorientation, allergic reactions and occasionally excitement – a high level of activity rather than becoming tired and falling asleep. Chloral Hydrate is readily available in three forms – syrup, capsule and suppository. Syrup is most successful for those 4 months and older, proper dosage is poured in an oral syringe or cup. The syringe is used to squirt in the back of the mouth and then the child is encouraged to swallow.

In slang, a Mickey Finn—or simply a Mickey—is a drink laced with a psychoactive drug or incapacitating agent (especially chloral hydrate) given to someone without their knowledge, with intent to incapacitate them.

Perper oversaw as Gertrude M. Juste and Stephen Cina examined and autopsied the body of Anna Nicole Smith in 2007. He also had significant involvement in the hearing deciding the fate of her body and has made numerous TV appearances on Nancy Grace and various other shows in relation to this. Perper revealed his findings that Smith's death was due to an accidental lethal combination of therapeutic levels of 3 benzodiazepines and chloral hydrate. Chloral hydrate was believed to be the major contributing factor.

Aldehydes can react with water to form hydrates, R−CH(OH)2. These diols are stable when strong electron withdrawing groups are present, as in chloral hydrate. The mechanism of formation is identical to hemiacetal formation.

Online product catalog page at Merck website. Accessed on 2020-07-11. The pharmacological effects of this compound in humans are similar to those of its prodrug chloral hydrate, and of chlorobutanol. Historically, it has been used as a sedative hypnotic.

The full investigative report has been made public and can be found online. Additionally, an official copy of the autopsy report was publicly released on March 26, 2007, and can be found online. Smith's death was ultimately ruled an accidental drug overdose of the sedative chloral hydrate that became increasingly lethal when combined with other prescription drugs in her system, specifically four benzodiazepines: Klonopin (clonazepam), Ativan (lorazepam), Serax (oxazepam) and Valium (diazepam). Furthermore, she had taken Benadryl (diphenhydramine) and Topamax (topiramate), both of which block sodium channels likely intensifying the sedative effects of the chloral hydrate and benzodiazepines.

The medical examiner stated that while Eagels had not consumed alcohol in the two days preceding her death, she had been "acting strangely" and suffering from hallucinations three or four days before she died. Toxicology reports revealed that Eagels still had alcohol in her organs when she died in addition to heroin and chloral hydrate (a sedative that Eagels regularly took to sleep). Her death was attributed to an overdose of the chloral hydrate. After services in New York at the Frank E. Campbell Funeral Chapel, Eagels received a second funeral service when her body was returned to Kansas City on October 7, where she was buried in Calvary Cemetery.

In the late 19th and early 20th centuries, acetophenone was used in medicine. It was marketed as a hypnotic and anticonvulsant under brand name Hypnone. The typical dosage was 0.12 to 0.3 milliliters. It was considered to have superior sedative effects to both paraldehyde and chloral hydrate.

Perper announced that Smith died of "combined drug intoxication" with the sleeping medication chloral hydrate as the "major component." No illegal drugs were found in her system. The official report states that her death was not considered to be due to homicide, suicide or natural causes.

In medicine, loss of normal thermoregulation in humans is referred to as "poikilothermia". This is usually seen with sedative and hypnotic drugs or in 'compartment syndrome'. For example, barbiturates, ethanol, and chloral hydrate may precipitate this effect. REM sleep is also considered a poikilothermic state in humans.

Drug treatment is indicated for patients with severe disabling chorea. It is treated with haloperidol, chlorpromazine alone or in combination with diazepam, and also pimozide, which is another neuroleptic drug which may have fewer adverse effects than haloperidol. Valproic acid, chloral hydrate, risperidone, or phenobarbital can also be used.

He gives Poirot detailed notes. Poirot accepts, then instructs Colin to talk further with the neighbours. At the inquest, the medical examiner explains that chloral hydrate was given to the victim before he was murdered. After the inquest, Edna Brent, one of the secretaries, expresses confusion at something said in evidence.

Under the name of Dr. C. W. Lemon he prescribed Williams with amphetamines, Seconal, chloral hydrate, and morphine.Koon, George William; p.74 Williams was scheduled to perform at the Municipal Auditorium in Charleston, West Virginia on Wednesday, December 31 (New Year's Eve), 1952. Advance ticket sales totaled US$3,500 (equivalent to US$ in 2011).

Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lends long term stability to multi- ingredient formulations. However, it retains antimicrobial activity at 0.05% in water.

At the trial the defense attorneys tried to blame her death on the absinthe and not the overdose of chloral hydrate. The jury rejected that the death was from the absinthe and that the murder was premeditated. In January 1902 Walter McAlister's attempt at pardon was denied by the New Jersey Board of Pardons.

It condenses readily with aldehydes, yielding with formaldehyde, on the addition of catalytic hydrochloric acid, methylene diresorcin [(HO)C6H3(O)]2•CH2. Reaction with chloral hydrate in the presence of potassium bisulfate yields the lactone of tetra-oxydiphenyl methane carboxylic acid.J. T. Hewitt and F. G. Pope, Jour. C/tern. Soc., 1897, 75, p.

Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses. It is administered intravenously to effect. For many years, it was the most commonly used injectable anesthetic in horses. Newer anesthetic agents such as injectable barbiturates, alpha-2 agonists, cyclohexylamines, and inhalants gradually replaced Equithesin.

192 — drowning in the bathtub. It seems likely that she knelt over the bathtub, took chloral hydrate, and plunged her head into the water.Bird and Sherwin, American Prometheus, p. 253. There has been, at times, speculation by historians and her brother Hugh as to whether her death was truly a suicide, as there were some suspicious circumstances.

Eric V. Anslyn, Dennis A. Dougherty (2006), Modern physical organic chemistry. University Science Books. . 1095 pages For conversion of hexafluoroacetone =O to the diol , the constant is about 10+6, due to the electron withdrawing effect of the trifluoromethyl groups. Similarly, the conversion of chloral =O to chloral hydrate is strongly favored by influence of the trichloromethyl group.

The 1800s brought increased technical sophistication. By the late 1880s, German dye manufacturers had perfected the purification of individual organic compounds from tar and other mineral sources and had also established rudimentary methods in organic chemical synthesis. thumb Chloral hydrate was introduced as a sleeping aid and sedative in 1869. Chloroform was first used as an anesthetic in 1847.

The Sandmeyer methodology is the oldest and straightforward way for the synthesis of isatin. The method involves the condensation between chloral hydrate and a primary arylamine (e.g. aniline), in the presence of hydroxylamine hydrochloride, in aqueous sodium sulfate to form an α‐isonitrosoacetanilide. Isolation of this intermediate and subsequent electrophilic cyclization promoted by strong acids (e.g.

It was reported that eight of the 11 drugs in Smith's system, including the chloral hydrate, were prescribed to Stern, not Smith. Additionally, two of the prescriptions were written for Alex Katz and one was written for Smith's friend and psychiatrist, Dr. Khristine Eroshevich. Perper acknowledged that all 11 prescriptions were written by Dr. Eroshevich. Smith's funeral took place on March 2, 2007.

The film was initially shot with British actor Anthony Bushell as Pierre, but he was replaced by March at Eagels' insistence.Films in Review Vol. 8, No. 8 (October 1957) page 412 Supporting actress Hilda Moore died before Jealousy was released, while the film's star, Jeanne Eagels, died of an overdose of chloral hydrate one month after the film was released.

In transtympanic recordings, a sedative can be used when time-consuming events need to take place. Most patients (especially infants) are given light anesthesia when test transtympanically. Chloral Hydrate is a commonly prescribed sedative, and most common for inducing sleep in young children and infants for AEP recordings. It uses alcohol to depress the central nervous system, specifically the cerebral cortex.

In a state of despondency over the loss of his love, he suffered a nervous breakdown and spent some time in the . After his release, he attempted suicide by gun. The shot barely missed his heart and left him permanently injured. In January 1891, unable to work and apparently suffering from persecution mania, he committed suicide with an overdose of chloral hydrate.

Hemorrhagic cystitis is rare when ifosfamide is given with mesna. A common and dose-limiting side effect is encephalopathy (brain dysfunction). It occurs in some form in up to 50% of people receiving the agent. The reaction is probably mediated by chloroacetaldehyde, one of the breakdown products of the ifosfamide molecule, which has chemical properties similar to acetaldehyde and chloral hydrate.

Bligh remained as a police magistrate in Gympie until his death in 1880 at the relatively young age of 46. He married and had several children. As a result of the kick to the face from the horse in Rockhampton, Bligh lost the sight in one eye and had chronic insomnia issues. He died of an overdose of chloral hydrate at his home in Gympie.

Drugs administered to a spider affect its ability to build a web. Webs produced under the influence of LSD (omitted in this image) show increased regularity. Caffeine has a significant effect on spiders, which is reflected in the construction of their webs. Psychoactive drugs, such as caffeine, amphetamine, mescaline, LSD, marijuana, chloral hydrate, theophylline, IBMX and others, can have strong effects on certain animals.

This time, attempts to induce vomiting were unsuccessful. Robert Cutler, a retired Stanford neurologist, recounted in The Mysterious Death of Jane Stanford what took place upon the arrival of Francis Howard Humphris, the hotel physician: > As Humphris tried to administer a solution of bromine and chloral hydrate, > Mrs. Stanford, now in anguish, exclaimed, 'My jaws are stiff. This is a > horrible death to die.

It has a taste resembling that of chloral hydrate and leaves a sharp irritation for some time. Cinnoline derivatives are obtained from oxycinnoline carboxylic acid, which is formed by digesting orthophenyl propiolic acid diazo chloride with water. Oxycinnoline carboxylic acid on heating gives oxycinnoline, melting at 225 °C, which with phosphorus pentachloride gives chlorcinnoline. This substance is reduced by iron filings and sulfuric acid to dihydrocinnoline.

On August 9, 1890, O'Reilly took an early boat to his residence in Hull, Massachusetts. He had been suffering from bouts of insomnia during this time. That evening he took a long walk with his brother-in-law John R. Murphy hoping that physical fatigue would induce the needed sleep. Later on that night he took some of his wife's sleeping medicine, which contained chloral hydrate.

Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and tension headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.

In February 2007, five months after her son Daniel Wayne Smith was found dead from CDI with methadone, sertraline, and escitalopram in his system, Anna Nicole Smith also died from CDI/MDI. Her two autopsies detected more than 11 drugs in her bloodstream, including chloral hydrate, clonazepam, lorazepam, oxazepam, diazepam, diphenhydramine, topiramate, oseltamivir, ciprofloxacin, methocarbamol, carisoprodol and others. The deaths of Daniel Smith and Anna Nicole Smith were declared as Combined Drug Intoxication.

Bird and Sherwin, American Prometheus, p. 251. In his report, the coroner found that Tatlock had eaten a full meal shortly before her death. She had taken some barbiturates, but not a fatal dose. Traces of chloral hydrate were found, a drug normally associated with a "Mickey Finn" when combined with alcohol, but there was no alcohol in her blood, despite damage to her pancreas that indicated she was a heavy drinker.

For agricultural research purposes, assessing the viability of pollen grains can be necessary and illuminating. A very common, efficient method to do so is known as Alexander's stain. This differential stain consists of ethanol, malachite green, distilled water, glycerol, phenol, chloral hydrate, acid fuchsin, orange G, and glacial acetic acid. In angiosperms and gymnosperms non-aborted pollen grain will appear red or pink, and aborted pollen grains will appear blue or slightly green.

Also chloral hydrate and guanethidine have been observed to increase BUN values. The 1886 Jaffé reaction, in which creatinine is treated with an alkaline picrate solution to yield a red complex, is still the basis of most commonly used methods for measuring creatinine. This reaction is nonspecific and subject to interference from many noncreatinine chromogens, including acetone, acetoacetate, pyruvate, ascorbic acid, glucose, cephalosporins, barbiturates, and protein. It is also sensitive to pH and temperature changes.

DCA has been shown to occur in nature in at least one seaweed, Asparagopsis taxiformis. It is a trace product of the chlorination of drinking water and is produced by the metabolism of various chlorine-containing drugs or chemicals. DCA is typically prepared by the reduction of trichloroacetic acid (TCA). DCA is prepared from chloral hydrate also by the reaction with calcium carbonate and sodium cyanide in water followed by acidifying with hydrochloric acid.

She obtains a job as personal secretary of Mrs. Hatch, a disreputable woman who very nearly succeeds in marrying a wealthy young man in Lily's former social circle. It is during this occupation she is introduced to the use of chloral hydrate, sold in drugstores, as a remedy for malaise. She resigns her position after Lawrence Selden returns to warn her of the danger, but not in time to avoid being blamed for the crisis.

For qualitative studies, a well-defined volume of solution was administered through a fine syringe. The webs were photographed for the same spider before and after drugging. Witt's research was discontinued, but it became reinvigorated in 1984 after a paper by J.A. Nathanson in the journal Science, which is discussed below. In 1995, a NASA research group repeated Witt's experiments on the effect of caffeine, benzedrine, marijuana and chloral hydrate on European garden spiders.

Daudet records observations, experiences, and aphorisms related to his intense suffering over the course of many years. He describes his symptoms in graphic detail and charts their progression. This begins with isolated attacks of agonising nerve pain, and eventually becomes a daily litany of pain and use of drugs like opium and chloral hydrate to fight it. He comments on the effect of his illness on family and friends, and on his outlook on life.

Amfecloral (INN), also known as amphecloral (USAN), is a stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It was classified as an anorectic drug with little to no stimulant activity in a 1970 review. The British Pharmacopoeia Commission approved the name in 1970. The raw ingredients used in manufacturing it were d-amphetamine and chloral hydrate.

Carr requested a doctor for Williams, who was feeling the combination of the chloral hydrate and alcohol he consumed on the way from Montgomery. A doctor injected Williams with two shots of vitamin B12 that contained morphine. Carr talked to Williams for the last time when they stopped at a restaurant in Bristol, Virginia. Carr later kept driving until he reached a gas station in Oak Hill, West Virginia, where Williams was discovered unresponsive in the back seat.

Peter Paul Pugin was only a year old when his father died. He later began practice as the junior partner in Pugin & Pugin, the family architectural firm. The senior partner was his half-brother Edward Welby Pugin. Pugin in 'The Dictionary of Scottish Architects When Edward Welby Pugin died suddenly on 5 June 1875 as a result of overwork and 'injudicious use of chloral hydrate', the main responsibility for the practice passed to Peter Paul Pugin.

When a patient was admitted to the hospital while intoxicated or at the end of a spree, the first thing that was done was to put the patient to sleep. The only medication given prior to the hypnotic was the four CC pills. The hypnotic Lambert found best contained chloral hydrate and morphine along with one or two grams of paraldehyde. If the patient went to sleep easily on this hypnotic it was safe to wake him every hour for his belladonna regimen.

As Murphy was leaving O'Reilly said to him "Be sure and be over early in the morning, Jack, so that you can go with me and the children to Mass at Nantasket". O'Reilly died later that morning on August 10, of a chloral hydrate overdose. While not the last person to see him alive, Murphy was one of the last people to see him before he overdosed. Murphy, along with his niece Mary, accompanied O'Reilly's body on a Boston steamer to Charlestown.

She attended John Bartram High School in Philadelphia, but had difficulty with her schoolwork due to emotional issues. She was institutionalized for one month during her childhood after attempting to commit suicide by overdosing on chloral hydrate. Shortly afterward, Fonder dropped out of high school and found social interactions increasingly difficult. Fonder worked various jobs during her early adulthood, including at a ceramics studio, a department store, various knitting factories, and the J.P. Lippincott publishing company, where she was a punchcard operator.

To ensure Cyril's victory, he spikes his opponents' water bottles with chloral hydrate. Cyril beats James Robson in the first round. As a result, Ryan wins money in the bets and the Aryans leave Cyril alone for good. From there, Ryan then spikes Miguel Alvarez's water and tells Alvarez's opponent, gay inmate Jason Cramer, that the Latinos will rape his lover if he loses the fight. Alvarez loses, the Latinos look worse, and Carmen Guerra grows suspicious of O’Reily's winning streak.

The use of iodine-containing solutions as an aid to describing and identifying fungi dates back to the mid-19th century. Melzer's reagent was first described in 1924 and takes its name from its inventor, the mycologist Václav Melzer, who modified an older chloral hydrate-containing IKI solution developed by botanist Arthur Meyer. Melzer was a specialist in Russula, a genus in which the amyloidy on the spore ornamentation or entire spore is of great taxonomic significance.The Russulales News Team. 2007.

In 1883, while staying in Nice, he was writing out his own prescriptions for the sedative chloral hydrate, signing them "Dr. Nietzsche". After severing his philosophical ties with Schopenhauer (who was long dead and never met Nietzsche) and his social ties with Wagner, Nietzsche had few remaining friends. Now, with the new style of Zarathustra, his work became even more alienating, and the market received it only to the degree required by politeness. Nietzsche recognized this and maintained his solitude, though he often complained.

A molecule of water may be eliminated, for example, by the action of sulfuric acid. Another example is chloral hydrate, CCl3−CH(OH)2, which can be formed by reaction of water with chloral, CCl3−CH=O. Many organic molecules, as well as inorganic molecules, form crystals that incorporate water into the crystalline structure without chemical alteration of the organic molecule (water of crystallization). The sugar trehalose, for example, exists in both an anhydrous form (melting point 203 °C) and as a dihydrate (melting point 97 °C).

Eventually, Lily Bart receives a ten-thousand-dollar inheritance from her Aunt Peniston, which she arranges to use to repay Gus Trenor. Distraught by her misfortunes, Lily has by this time begun regularly using a sleeping draught of chloral hydrate to escape the pain of poverty and social ostracism. Once she has repaid all her debts, Lily takes an overdose of the sleeping draught and dies; perhaps it is suicide, perhaps an accident. As she is dying, she hallucinates cradling Nettie's baby in her arms.

The toxicological analysis concluded that the cause of death was acute barbiturate poisoning; she had 8 mg% (mg/dl) of chloral hydrate and 4.5 mg% of pentobarbital (Nembutal) in her blood and a further 13 mg% of pentobarbital in her liver. The police found empty bottles of these medicines next to her bed. There were no signs of external wounds or bruises on the body. The findings of the inquest were published on August 17; Chief Coroner Theodore Curphey classified Monroe's death a "probable suicide".

In order to monitor her drug use, they had agreed to never prescribe her anything without first consulting with each other. Monroe was able to persuade Engelberg to break his promise by lying to him that Greenson had agreed to it. She took several Nembutals on August 4, but did not tell this to Greenson, who prescribed her a chloral hydrate enema; the combination of these two drugs killed her. Afraid of the consequences, the doctors and Monroe's housekeeper then staged the death as a suicide.

Kit is summoned to the Bank of Prussia where he learns he's been financially cut off from the Vibes. Yashmeen offers to help him find a position with T.W.I.T. Kit encounters Foley Walker, “the angel, if not of death at least of deep shit,” and decides he needs to leave Göttingen soon. He attends a chloral hydrate party and is pursued by Walker until taking refuge in a hospital. Kit is moved to a mental hospital where the patients await the arrival of a Dirigible.

Marshall admitted that he had also prescribed chloral hydrate to his recently deceased wife, Faye, as a headache medicine. He denied any responsibility in both deaths. On March 21, Robert Travis of the State Crime Bureau determined that Marshall's handwriting corresponded to that of Dr. Cecil W. Lemmon on six prescriptions written for Williams. The same day, the District Attorney's office declared that after a new review of the autopsy report of Faye Marshall, toxicological and microscopic tests confirmed that her death on March 3 was not related to the medication prescribed by her husband.

Two of her protegees, Albert Ives and Robert Sherrod, killed Leland Cash during a mugging (when he reached into his pocket to turn up his hearing aid, Ives assumed he was reaching for a gun and shot Cash in the stomach). Fearing Sherrord would confess to the police, Spinelli gave him whiskey that she had laced with chloral hydrate. The gang then beat him up whilst he was unconscious. To make his death appear accidental, they threw him off the Clarksburg bridge on the Sacramento River, just south of Sacramento, wearing only swimming trunks.

In the apartment, police found empty beer bottles, a bottle with chloral hydrate crystals in it, a carving knife with blood on it, and blood on bedsheets, in a closet, under the kitchen sink, and on the floor and walls. The words "blood atonement" were scrawled in a notebook, and underneath were several references to verses in the Bible that discuss atonement for crime. It was determined that Pulitzer had died of a drug overdose from chloral poisoning and that the head bruising and abdomen stabbing occurred after her death.

The brand was acquired by GlaxoSmithKline.GlaxoSmithKline: Synthol Liquid – for dermal use and mouth wash (450 ml) Synthol Liquid is recommended for application to the skin, or as a supplementary treatment for mild traumas (such as cuts and bruises) or insect bites and stings. Suitable for adults and children over 7 years Formerly the formula consisted of chloral hydrate, menthol, veratrol, resorcinol and salicylic acid. Sold mainly as a mouthwash in a distinctive black carton, it is also packaged as a gel and spray for the treatment of muscular pain(s).

Marshall had been previously convicted for forgery, and had been paroled and released from the Oklahoma State Penitentiary in 1951. Among other fake titles, he said that he was a Doctor of Science. He purchased the DSC title for $25 from the Chicago School of Applied Science; in the diploma, he requested that the DSC be spelled out as "Doctor of Science and Psychology". Under the name of Dr. C. W. Lemon he prescribed Williams with amphetamines, Seconal, chloral hydrate, and morphine, which made his heart problems worse.

A search of the home revealed a large cache of weapons and illegal drugs. Police confiscated several pipe bombs, handguns, rifles, shotguns, a machine gun, Rohypnol, chloral hydrate, marijuana, a live puff adder, venom collecting apparatus, and floor plans for several area notable residences and businesses. During questioning, Fitzgerald told police of a third body, that of a young woman, that Biegenwald had shown him hidden in his garage. This victim was driven to the rear of Burger King in Ocean Township, and dumped in the wooded area behind.

When Augustus Hill testifies against Malcolm Coyle for murdering an innocent family, Saïd asks Schillinger, among other inmates, to help protect him. Schillinger agrees because he also is a family man and respects the fact that one member of the family died while serving in Vietnam. CO Sean Murphy starts a boxing tournament in Emerald City, to which Robson agrees to compete for the Aryans. Schillinger taunts Cyril about the gang rape before he fights Robson, but Ryan pours chloral hydrate in Robson's water, thus allowing his brother to win the match.

790 Apart from some minor medical applications, the first commercial use was the daguerreotype. In 1840, bromine was discovered to have some advantages over the previously used iodine vapor to create the light sensitive silver halide layer in daguerreotypy. Potassium bromide and sodium bromide were used as anticonvulsants and sedatives in the late 19th and early 20th centuries, but were gradually superseded by chloral hydrate and then by the barbiturates. In the early years of the First World War, bromine compounds such as xylyl bromide were used as poison gas.

85 Lansdowne met both the Munshi and Waziruddin privately, and Lady Lansdowne met his wife and mother-in-law, who were smuggled into the Viceroy's camp in secrecy to comply with rules of purdah.Basu, pp. 86–87 In 1891, after Karim's return to Britain, he asked Reid to send his father a large quantity of medicinal compounds, which included strychnine, chloral hydrate, morphine, and many other poisons. Reid calculated that the amount requested was "amply sufficient to kill 12,000 to 15,000 full grown men or an enormously large number of children" and consequently refused.

Ms Blood was identified as Linda Woolard. In an effort to find out who breached the file that corroborated the attempted frame up of Klemesrud, Scientology enlisted the Los Angeles Police Department to seek help from Interpol, alleging that it was a hacker. (See Second compromise) Klemesrud wrote a letter to the LAPD that Scientology already knew and silenced the anonymous poster. In 2002, Keith Henson compiled what was known of the story to that time, and a year later Tom Klemesrud executed a declaration about being dosed with chloral hydrate.

By 1874, the Chicago Tribune published a story about abuse, neglect and government corruption with the facility. In an 1886 state investigation, one of the sedatives used at Dunning was a mixture containing chloral hydrate as well as cannabis, hops and potash. The investigation also found that Dunning was apparently serving two kegs of beer daily to both patients and employees. A lack of fruit and fresh vegetables had caused an epidemic of scurvy, with about 200 patients suffering from the illness, according to the same investigation. “The cooking, we are convinced, was bad,” the investigators said.

Wynekoop then sent a boarder, Enid Hennessey, a school teacher, on an errand to buy some chloral hydrate. When Hennessey returned, the two had supper together. Rheta was not at supper, Wynekoop said, and when she was still missing a few hours later, Wynekoop became concerned and began searching the house, finally finding her daughter-in-law's body on the table in her surgery. Wynekoop immediately phoned two of her children, Catherine and Walker, and then summoned the undertaker, who realized two hours later that Wynekoop had failed to notify the police and did so himself.

Their romantic relationship is reputed to have started in 1865 and lasted, on differing levels, until his death in 1882. They shared a deep emotional connection, and she inspired Rossetti to write poetry and create some of his best paintings. Her discovery of his dependence on the drug, chloral hydrate, which was taken for insomnia, eventually led her to distance herself from him, although they stayed in touch until he died in 1882. In 1883, Jane Morris met the poet and political activist Wilfrid Scawen Blunt at a house party given by her close friend, Rosalind Howard (later Countess of Carlisle).

Karl Koller (December 3, 1857 – March 21, 1944) was an Austrian ophthalmologist who began his medical career as a surgeon at the Vienna General Hospital and a colleague of Sigmund Freud. Koller introduced cocaine as a local anaesthetic for eye surgery. Prior to this discovery, he had tested solutions such as chloral hydrate and morphine as anaesthetics in the eyes of laboratory animals without success. Freud was fully aware of the pain-killing properties of cocaine, but Koller recognized its tissue-numbing capabilities, and in 1884 demonstrated its potential as a local anaesthetic to the medical community.

Alcohol, consumed voluntarily, is the most commonly used drug involved in sexual assaults. Since the mid-1990s, the media and researchers have also documented an increased use of drugs such as flunitrazepam and ketamine to facilitate sexual assaults in the context of dating. Other drugs that have been used include hypnotics such as zopiclone, methaqualone and the widely available zolpidem (Ambien), sedatives such as neuroleptics (anti-psychotics), chloral hydrate and some histamine H1 antagonists, common recreational drugs such as ethanol, cocaine, and less common anticholinergics, barbiturates, opioids, PCP, scopolamine, nasal spray ingredient oxymetazoline, and certain solvents like GHB, GBL, and BD.

"Drinking the Kool- Aid" is a phrase suggesting that one has mindlessly adopted a dogma of a group or a (cult) leader without fully understanding the ramifications or implications. The backdrop of this are events culminating in the 1978 Jonestown Massacre. At Jonestown, Guyana, followers of Jim Jones' Temple drank from a metal vat containing a mixture of "Kool Aid", cyanide, and prescription drugs Valium, Phenergan, and chloral hydrate. Present-day descriptions of the event sometimes claim the beverage was not as Kool-Aid but Flavor Aid, a less- expensive product from Jel Sert reportedly found at the site.

Although sailors' homes and crimp houses had previously been using "knock-out drops" and "slipping mickeys" to shanghai sailors, Sawyer was the first to make effective use for armed robbery. At first, Sawyer used simple snuff which he dropped into the victim's alcohol but perfected the practice later on with chloral hydrate. This was the drug of choice, with exception to the occasional use of morphine, preferred by those who followed Sawyer in similar robberies. Indeed, the practice became so common in the city that these men were referred to as "Peter Players" by the police and underworld alike.

Robson reappears, this time as a full-fledged member of the Aryan Brotherhood inside of Oz. He serves little purpose in season 3 other than following Schillinger's schemes and encouraging him to do whatever he needs to do to maintain the power of the Brotherhood. He also participates in Oz's boxing tournament, as the Aryans' representative. He faced Cyril O'Reily, but unbeknownst to him, Cyril's older brother Ryan had spiked Robson's drinking water with chloral hydrate (stolen and smuggled from the prison hospital) to make sure Cyril wouldn't lose. Robson, incapacitated by the drug, loses the fight.

On 11 July 1998, three years after her release, Wistrich and Bindel found Humphreys dead in bed at her home from an apparently accidental overdose of chloral hydrate. In September 2000, Humphreys' family doctor told the inquest, at St Pancras Coroner's Court, that Humphreys was first prescribed the drug in Holloway prison because she had had difficulty sleeping. According to a friend, she had taken too much of the drug several times since her release, and seemed to be addicted to it. When she died, she weighed just 70 lbs (five stone) and had 20 times the recommended dose in her blood.

Séducteur by . (A corrupt old man tries to seduce a woman by urging her to take a hypnotic draught in her drink) Hypnotica was a class of somniferous drugs and substances tested in medicine of the 1890s and later, including: Urethan, Acetal, Methylal, Sulfonal, paraldehyde, Amylenhydrate, Hypnon, Chloralurethan and Ohloralamid or Chloralimid.Pacific Record of Medicine and Surgery - Volume 5 - Page 36 1890 Research about using medications to treat insomnia evolved throughout the last half of the 20th century. Treatment for insomnia in psychiatry dates back to 1869 when chloral hydrate was first used as a soporific.

On May 9, 1961, while campaigning as a candidate for sheriff of Campbell County, Kentucky, he was drugged with chloral hydrate and put in bed with stripper April Flowers in an attempt to blackmail him and force him to drop from the race. The plot was uncovered, and publicity from the botched frame-up attempt catapulted him and his party to victory in the election. While sheriff, with cooperation from federal agents and personal interest of then-U.S. Attorney General Robert F. Kennedy, he was able to rid the county, and particularly the city of Newport, of gambling, prostitution and vice businesses that had dominated the area since the Civil War.

After a failed attempt the previous evening, Realf killed himself by taking chloral/chloral hydrate and laudanum at the Windsor House in Oakland, California on October 28, 1878. He committed suicide in consequence of an unfortunate marriage and an imperfect divorce. He appointed as his literary executor Colonel Richard J. Hinton, who, after an initial gathering of the poet's scattered fragments performed by Ina Coolbrith, completed the collection of Realf's poems for publication, together with a biographical sketch, in 1888. Realf is buried in Section OSA, Row 72, Grave #4 of the San Francisco National Cemetery located in the Presidio of San Francisco, California.

Liebreich introduced the method of phaneroscopic illumination for the study of lupus; showed the value of cantharidin in tuberculosis, of mercuric formamide and of lanolin in syphilis, of butylchloral hydrate and of ethylene chloride The modern chemical which has anesthetic properties which is referred to as ethylene chloride is vinyl chloride, which is toxic. as anesthetics. In 1865, he gave the name "protagon" to a proximate principle discovered in the brain and in blood corpuscles. He is well known for his investigations pertaining to the sedative and hypnotic properties of chloral hydrate (1869), and was an important factor in the drugs' popularity during the latter half of the 19th century.

The type and severity of symptoms displayed vary among patients and even at different ages on the same patients so patients should have specialized individual treatment plans. Medications are used to control vomiting, eye dryness, and abnormal blood pressure. Common management strategies include: artificial tears, appropriate feeding strategy (maintenance of adequate nutrition, avoidance of aspiration (thickened formula and different shaped nipples for infants)), daily chest physiotherapy (nebulization, bronchodilators, and postural drainage) for chronic pulmonary disease, pharmaceutical management of autonomic features (e.g. intravenous or rectal diazepam, or rectal chloral hydrate), preventing accidental injury, prevention of orthostatic hypotension (hydration, leg exercise, frequent small meals, a high-salt diet, and medication (e.g.

Many sedative/hypnotic drugs act by binding to and potentiating GABA-A receptors. These include older drugs such as ethanol, chloral hydrate and barbiturates, as well as newer benzodiazepines and "non-benzodiazepine" drugs (such as zolpidem, which bind to the same receptor but have a different chemical configuration), and even anesthetics such as propofol and isoflurane. As the VLPO inputs to the arousal system use this same receptor, these drugs at low doses essentially act by potentiating the VLPO, producing a sleepy state. Animal studies show that VLPO neurons show cFos activation after sedative doses of these drugs, and that VLPO lesions produce resistance to their sedative effects.

However, at high doses that produce a surgical plane of anesthesia, these drugs have much more widespread inhibitory effects, that do not depend upon the VLPO. Studies have shown that multiple sedative/hypnotic drugs that act by potentiating GABA-A receptors, including ethanol, chloral hydrate, propofol and gas anesthetics such as isoflurane, at sedative doses increase the activity of the VLPO neurons in mice. This finding suggests that at relatively low sedative doses, these medications may have a common mechanism of action, which includes potentiating the firing of VLPO neurons. High doses used in surgical anesthesia, however, reduce activity of neurons throughout the nervous system.

They arrived at the Andrew Johnson Hotel in Knoxville, Tennessee, where Carr requested a doctor for Williams, as he was feeling the combination of the chloral hydrate and alcohol he had drunk on the way from Montgomery to Knoxville. Dr. P. H. Cardwell injected Williams with two shots of vitamin B12 that also contained a quarter-grain of morphine. Carr and Williams checked out of the hotel; the porters had to carry Williams to the car, as he was coughing and hiccuping. At around midnight on Thursday, January 1, 1953, when they crossed the Tennessee state line and arrived in Bristol, Virginia, Carr stopped at a small all-night restaurant and asked Williams if he wanted to eat.

Aside from employment within the hospital and social activities, such as dances and concerts, which often were led by the staff but also involved visits from or to external organisations, treatment was initially limited to sedation using chloral hydrate and, from 1871, Turkish baths. It seems from the comments of the Medical Superintendent of the time that the baths were intended to treat the body odours that he thought to be a symptom of insanity. The hospital spent more on alcohol than on drugs until the early 1900s. It was from around the same time, with the arrival of a new Assistant Medical Officer, that social events expanded to include sports such as tennis and football.

They did not want him admitted officially, as his drug addiction would become public and they would fall under suspicion, although some of them admitted that any ordinary person in his condition would have been admitted immediately. On Vysotsky's death his associates and relatives put in much effort to prevent a post-mortem being carried out. This despite the fairly unusual circumstances: he died aged 42 under heavy sedation with an improvised cocktail of sedatives and stimulants, including the toxic chloral hydrate, provided by his personal doctor who had been supplying him with narcotics the previous three years. This doctor, being the only one present at his side when death occurred, had a few days earlier been seen to display elementary negligence in treating the sedated Vysotsky.

Three weeks before the litigation against Klemesrud in February 1995, an incident occurred as a result of an intelligence breach of a file from the internal Scientology computer system, known as INCOMM, or the International Network of Computer Organized Management.List of trademarks owned by the Church of Scientology and its affiliates The incident presented evidence of Fair Game by Scientology, as they tried to frame Klemesrud for attacking a female in his apartment who had drugged him with chloral hydrate on January 14, 1995. Klemesrud was arrested on a charge of assault with a deadly weapon and released on $30,000 bail the next morning, while the woman was allowed to leave the scene without any examination. A police detective was subsequently unable to contact her.

Very limited evidence indicates that topiramate or pregabalin may be useful in the treatment of alcohol withdrawal syndrome. Limited evidence supports the use of gabapentin or carbamazepine for the treatment of mild or moderate alcohol withdrawal as the sole treatment or as combination therapy with other medications; however, gabapentin does not appear to be effective for treatment of severe alcohol withdrawal and is therefore not recommended for use in this setting. A 2010 Cochrane review similarly reported that the evidence to support the role of anticonvulsants over benzodiazepines in the treatment of alcohol withdrawal is not supported. Paraldehyde combined with chloral hydrate showed superiority over chlordiazepoxide with regard to life-threatening side effects and carbamazepine may have advantages for certain symptoms.

There, he helped Pasteur and Emile Roux in their classic experiments of vaccination of animals against anthrax at Pouilly-le-Fort. In 1883, he traveled to Egypt with Roux, Straus, and Thuiller, in order to study an outbreak of cholera there, but they were unable to isolate the germ responsible for the disease. He returned on the same year to Alfort, and established a well-equipped research laboratory, in close liaison with Pasteur's. In the next three years, Nocard demonstrated his great skills in laboratory work in the new science of bacteriology by developing a number of new techniques, such as methods of harvesting blood serum, new culture media for the bacillus of tuberculosis, the introduction of anesthesia of large animals with intravenous chloral hydrate, as well as for controlling tetanic convulsions.

He became a surgeon in the Confederate army, and was president of the board for the admission of surgeons, and chief officer on the medical staff of Gen. Joseph E. Johnston, and served with him until the battle of Seven Pines. He was then ordered to build and organize the hospitals at Danville, Virginia, and afterward had charge of the military hospital at Staunton, Virginia, until the war ended. He remained and practised at Staunton after the war, and was for several years superintendent of the lunatic asylum at that place. His contributions to medical literature include papers on potassium bromide, chloral hydrate, the use of chloroform in obstetrical practice, and a “Report upon Advance in Therapeutics,” which was printed in the Transactions of the Virginia Medical Society.

When Lady Shrewsbury (Roger Shrewsbury's domineering mother), dies soon after a violent argument with Charlotte's older sister, Olivia, Charlotte becomes alarmed that "Livia" or her parents will be suspected in the death. "Sherlock Holmes" writes a letter to Scotland Yard, suggesting a connection between Lady Shrewsbury's death, and the deaths, occurring within weeks of each other, of Lady Amelia Drummond and The Honourable Harrington Sackville. All three victims were connected by family or marriage ties, and all three appeared to have died from an accidental overdose of chloral hydrate. Inspector Treadles, a firm believer in "Sherlock Holmes"' abilities, investigates Sackville's death more closely, but does not find any definite proof of foul play until a consultation with "Holmes" via Charlotte, leads him to discover that the local doctor's supply of strychnine – the most effective antidote for an overdose of chloral – was removed before the night of Mr. Sackville's death.

It has been our practice with similar > information collected in other cases in the past to recommend a > certification for such deaths as probable suicide. Additional clews for > suicide provided by the physical evidence are the high level of barbiturates > and chloral hydrate in the blood which, with other evidence from the > autopsy, indicates the probable ingestion of a large amount of drugs within > a short period of time: the completely empty bottle of Nembutal, the > prescription for which (25 capsules) was filled the day before the > ingestion, and the locked door to the bedroom, which was unusual. In the 1970s, claims surfaced that Monroe's death was a murder and not suicide. Due to these claims, Los Angeles County District Attorney John Van de Kamp assigned his colleague Ronald H. "Mike" Carroll to conduct a 1982 "threshold investigation" to see whether a criminal investigation should be opened.

In addition to this list of some of the new substances he prepared, reference may be made to his work on abnormal vapor densities. While working on the olefins he noticed that a change takes place in the density of the vapor of amylene hydrochloride, hydrobromide, &c;, as the temperature is increased, and in the gradual passage from a gas of approximately normal density to one of half-normal density he saw a powerful argument in favor of the view that abnormal vapor densities, such as are exhibited by sal-ammoniac or phosphorus pentachloride. are to be explained by dissociation. From 1865 onwards he treated this question in several papers, and in particular maintained the dissociation of vapor of chloral hydrate, in opposition to Etienne Henri Sainte-Claire Deville and Marcellin Berthelot. For twenty-one years (1852–1872) Wurtz published in the Annales de chimie et de physique abstracts of chemical work done out of France.