The chimeric creatures have remained more or less a mystery.
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In both cases the chimeric animals were not brought to term.
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Both the paintings and the rooms conjure a chimeric, visionary state.
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Rosenberg's chimeric prose prevents all of this from feeling too pedantic.
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JCAR015 is an experimental chimeric antigen receptor T-Cell (CAR-T) therapy.
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Does Synthesis depict the plumage of a peacock or chimeric alien foliage?
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The treatment is a CAR-T — for chimeric antigen receptor T-cell therapy.
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Martha's Vineyard's ponds are chimeric; not quite the sea, not quite not the sea.
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A chimeric shimmer of how it felt to be carried from place to place.
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ND: Can we talk about the Chimera room [Saya Woolfalk "ChimaTEK: Virtual Chimeric Space" (2015)]?
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Tisagenlecleucel is a type of immunotherapy called chimeric antigen receptor T-cell therapy, or CAR-T.
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SMS, Skype, and a few other chat apps will get folded into one big chimeric messaging center.
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The modified cells, called chimeric antigen receptor T-cells, or CAR-T, are infused into the patient.
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The agreement also covers the supply of vectors for other undisclosed Chimeric Antigen Receptor T cell (CART) products.
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The modified cells, called chimeric antigen receptor T-cells, or CAR-T, are then infused into the patient.
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This chimeric nightmare was posted earlier this week to obtuse, anti-humorous Facebook group Wet and Soggy Memes.
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Titled New Path, their latest record was conceptually inspired by Phillip K. Dick's chimeric masterwork A Scanner Darkly.
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Why must "what is real and possible" be continuously rejected "in favor of what is imaginary and chimeric"?
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The technology along these lines that has got furthest is called CAR-T, where CAR stands for "Chimeric antigen receptor".
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At UC Davis, the Guardian reports, researchers have created chimeric embryos that carry both human stem cells and pig DNA.
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Kymriah was the first so-called chimeric antigen T-cell therapy (CAR-T) to be approved in the United States.
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In 2015, the organization said that it wouldn't be funding new chimeric research until any new guidelines were taken under review.
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Netflix has popped off 20133 by loading a ton of high-octane sci-fi and dreamy fantasy into its chimeric catalog.
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Chimeric antigen receptor T-cell therapy, or CAR T, harnesses the body's own immune cells to recognize and attack malignant cells.
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Chimeric antigen receptor T-cell therapy, known as CAR-T, harnesses the body's own immune cells to recognize and attack malignant cells.
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Companies like Bluebird and Juno work with what is known as chimeric antigen receptor T-cell immunotherapy, also known as CAR-T.
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It's Callichimaera perplexa, a thoroughly weird Cretaceous species named after the chimeric combination of features that make it such a unique find.
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Researchers at the University of Pennsylvania's Abramson Cancer Center started activating cells with chimeric antigen receptors in the early 2000s, Grupp says.
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Specifically, JW is focused on the next-generation of cell-based immunotherapy cancer treatments using chimeric antigen receptor T-cell (CAR-T) technologies.
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Just days before its chimeric folding phone was supposed to go on sale, Samsung yanked the Galaxy Fold off the market (for now).
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Xyphos' proprietary molecules can be delivered to natural immune cells or to engineered Chimeric Antigen Receptor (CAR) cells to generate immunotherapies for oncology.
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But the reveal of Prey's Talos 1's is not a vision of its imposing shape, its blacks and golds, or its chimeric gargoyles.
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Both are chimeric antigen receptor T-cell therapies, or CAR-Ts, which reprogram the body's own immune cells to recognize and attack malignant cells.
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Both Yescarta and Kymriah are chimeric antigen receptor T-cell therapies, or CAR-Ts, which reprogram the body's own immune cells to attack malignant cells.
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Eventually, Oregon State University biologist George Poinar deemed the chimeric monster to be some kind of Hymenoptera, the insect order comprising wasps, bees, and ants.
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There's particular concern that the genetic material from humans might cause the chimeric pigs to develop human-like brains, but experts believe this is unlikely.
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A subset of immunotherapy, CAR-T stands for chimeric antigen receptor T-cell therapy, and it's the focus of a handful of companies' development programs.
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The resultant works, however, are chimeric and alive—far from the dystopian future so popular in media and the rote cleanliness of a Silicon Valley.
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Kymriah and Gilead's Yescarta are chimeric antigen receptor T-cell therapies, or CAR-Ts, which reprogramme the body's own immune cells to attack malignant cells.
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Kymriah and Gilead's Yescarta are chimeric antigen receptor T-cell therapies, or CAR-Ts, which reprogram the body's own immune cells to attack malignant cells.
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First, doctors take the patient's white blood cells, or T cells, out of the body and add a special receptor called a chimeric antigen receptor (CAR).
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Engineered T cell therapies, such as CAR-T therapy (or chimeric antigen receptor T cell therapy), can produce long-lasting remission in patients with blood cancers.
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What is called CAR-T therapy starts with the gene for a chimeric antigen receptor (CAR), a protein which sits on the surface of a cell.
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Both said they could receive initial regulatory approvals next year for a type of immunotherapy treatment known as chimeric antigen receptor T-cell (CAR-T) therapies.
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Kymriah, a chimeric antigen receptor T cell (CAR-T) therapy, in August won FDA approval against acute lymphoblastic leukemia in patients up to 25 years old.
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But given the uncanny dada combinations of incongruous elements found here, this connection is historically chimeric: There isn't a scintilla of evidence to support such speculation.
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Juno focuses on chimeric antigen receptor T-cell therapy, known as CAR-T, which harnesses the body's own immune cells to recognize and attack malignant cells.
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In the new therapy, a subset of T cells were armed with chimeric antigen receptors, or CARs, using gene transfer, making them better at targeting cancer cells.
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Both Kymriah and Yescarta are chimeric antigen receptor T-cell therapies, or CAR-Ts, which reprogram the body's own immune cells to recognize and attack malignant cells.
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This therapy -- known as chimeric antigen receptor T-cell therapy, or CAR-T -- gives the cells the ability to recognize and kill the source of the cancer.
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O both said they could receive initial regulatory approvals next year for a type of immunotherapy treatment known as chimeric antigen receptor T-cell (CAR-T) therapies.
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The therapy is part of a new class known as chimeric antigen receptor T-cells (CAR-T) designed to reprogram immune system cells to attack cancer cells.
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"Fresh human tissues are required for implantation into severely immune-compromised mice to create chimeric animals that have a human immune system," FDA said at the time.
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The biopharmaceutical company has been developing chimeric antigen receptor technology, a line of therapies that would teach certain white blood cells how to recognize and kill cancer cells.
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The story comes to a head when Gon joins up with his father's protégé Kite to hunt down chimeric ants, which take on characteristics of whatever they eat.
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Kymriah, a chimeric antigen receptor T cell (CAR-T) therapy, in August won FDA approval for treatment of acute lymphoblastic leukemia in patients up to 25 years old.
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The drugs use a new technology known as CAR-T, or chimeric antigen receptor T-cell therapy, which harnesses the body's own immune cells to recognize and attack malignant cells.
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The agreement will accelerate the development of Pfizer's chimeric antigen receptor T cell (CAR T) therapy, an investigational immune cell therapy for treating cancer, the company said in a statement.
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Santa Monica, California-based Kite is developing a CAR-T, or chimeric antigen receptor T-cell therapy, which harnesses the body's own immune cells to recognize and attack malignant cells.
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The chimeric antigen receptor therapy developed by Novartis, called CAR-T, is poised to become the first of its kind to secure FDA approval, ahead of Kite Pharma and Juno Therapeutics.
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Santa Monica, California-based Kite is developing chimeric antigen receptor T-cell therapy, known as a CAR T, which harnesses the body's own immune cells to recognize and attack malignant cells.
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"However, uncertainty about the effects of human cells on off-target organs and tissues in the chimeric animals, particularly in the nervous system, raises ethical and animal welfare concerns," she added.
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Kymriah is a chimeric antigen receptor T cell (CAR-T) therapy in which patients' immune cells are taken from their bodies, genetically re-engineered to fight their cancer and then reinfused.
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Experimental chimeric antigen receptor T-cells, or CAR-Ts, are made by genetically altering a patients' own T-cells in the lab to help the immune system find and kill cancer cells.
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In 2017, the Food and Drug Administration approved the first chimeric antigen receptor T cell (CAR-T) therapies, enabling doctors to use a patient's own immune system cells to fight cancer cells.
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In August, Novartis disbanded its stand-alone Cell and Gene Therapy unit, eliminating 120 mostly U.S. jobs while inserting promising programs such as chimeric antigen replacement therapy, or CART, into its oncology business.
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In August, Novartis disbanded its stand-alone Cell and Gene Therapy unit, eliminating 120 mostly U.S. jobs while inserting promising programmes such as chimeric antigen replacement therapy, or CART, into its oncology business.
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Chimeric antigen receptor T-cell therapy, known as CAR-T, involves drawing white blood cells from a patient, processing them in the lab to target cancer, and infusing the cells back into the patient.
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Gilead is betting that the money-losing Kite Pharma will receive FDA approval for its CAR-T, or chimeric antigen receptor T-cell, therapy, which would advance a much sought-after cancer-fighting treatment.
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Here's how the researchers created the chimeric human-monkey embryos, as El País reported: First, the researchers created genetically modified monkey embryos in which the genes responsible for the normal formation of organs were disabled.
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So Rochester 585/716 doesn't read like a polyphonic visual story, but rather like some big photographic experiment, one that treats the medium's somewhat chimeric promises — to represent, to capture — as hypotheses to be tested.
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Projects like Leonce Raphael Abgodjélou's documentary photographs of egungun dancers in Benin and Saya Woolfalk's "ChimaTEK Virtual Chimeric Space" (2012) show how performance traditions incorporating African masks endure today and may be adapted in the future.
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Airbus unveiled the concept at the Royal International Air Tattoo air show in the UK. The French aerospace giant thankfully has no plans to build or manufacture this chimeric monstrosity, which is probably for the best.
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Chimeric antigen receptor T-cell, or CAR-T, therapies extract immune system T-cells from an individual patient, alter their DNA to better spot and kill cancer cells, and infuse them back into the same patient.
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The drug, Yescarta, is the second in a new class of cancer treatments known as chimeric antigen receptor T-cell therapy, or CAR-T, which reprograms the body's own immune cells to recognize and attack malignant cells.
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This would be the second indication for the first-ever chimeric antigen receptor T cell (CAR-T) therapy that was approved by the FDA in August against acute lymphoblastic leukemia in patients up to 25 years old.
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Chimeric antigen receptor T-cell, or CAR-T, therapies are made by extracting a patient's immune system T cells, altering their DNA to sharpen their ability to spot and kill cancer cells, and infusing them back into the same patient.
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You could go for long stretches without seeing any action at all; suddenly you'd see a stampede of people chasing a lone actor down a hallway, as if he were a chimeric forest creature leading the way to an elusive treasure.
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The same technique — injecting pluripotent stem cells into early embryos — failed with other combinations: The scientists couldn't create rat-pig chimeras, and although they produced human-cow chimeric embryos, they did not transfer them into cows to develop into fetuses.
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When I first heard the music of Best Coast—chimeric as Fleetwood Mac, slightly nostalgic in a Beach Boys way, bad-ass and lo-fi too—I was living in New York City, thousands of miles from Venice Beach where I live now.
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Yescarta, approved by the U.S. Food and Drug Administration in October 2017 for aggressive large B-cell lymphoma that has not responded to other treatments, is part of a new class known as chimeric antigen receptor T-cell therapies, or CAR-Ts.
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The chimeric Sherman probably is the central artist of the exhibition, with 23 of her works included, which may have been too long a march through the female unconscious, considering there are none by Carolee Schneemann or the great hybrid poseur Pierre Molinier.
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After a long period in the doldrums, shares in the group are up 112 percent this year, buoyed by rising optimism for CTL019, which represents the first in a new class of medicines known as CAR-T, or chimeric antigen receptor T-cell therapy.
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The therapy belongs to a class of drugs known as chimeric antigen receptor T-cell therapy or CAR-T, which involves drawing white blood cells from a patient, processing them in the lab to target cancer, and infusing the cells back into the patient.
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The FDA is also taking steps to streamline and standardize the review of manufacturing processes for gene therapies and cell based products, such as new chimeric antigen receptor T-cell therapies, or CAR-Ts, which involve removing and altering patients' immune cells to recognize and attack cancer.
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Few details are known, but the experiment, in which the researchers created chimeric, or hybridized, human-monkey embryos using human stem cells, is "an important step towards [Izpisúa Belmonte's] final goal of converting animals of other species into factories of organs for transplants," reports El País.
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CAR-T therapies, shorthand for chimeric antigen receptor T-cell, are part of a hot new approach to fighting cancer in which doctors remove infection-fighting immune cells known as T-cells, genetically engineer them to recognize and attack cancer, and infuse them back into the patient.
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It's chimeric: a meditation on the construction of masculinity, masochism, the psychology of desire, queerness, as well as the simultaneous erasure and development of the feminine in men loving and desiring each other; it also meditates on the fine lines between love, being loved, fucking, and being fucked.
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The new drug class, known as chimeric antigen receptor T-cell or CAR-T, involves a complicated process of extracting immune system T-cells from an individual patient, altering the cell DNA to sharpen their ability to spot and kill cancer cells, and infusing them back into the patient.
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The question of how long patients will benefit from Yescarta and other therapies in an expensive new class known as chimeric antigen receptor T-cell therapies, or CAR-Ts, has been a key topic at the annual meeting of the American Society of Hematology (ASH) in San Diego.
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Both companies are developing drugs in a new class called chimeric antigen receptor T-cells (CAR-T) using a complicated process of extracting immune system T-cells from an individual patient, altering their DNA to sharpen their ability to spot and kill cancer cells, and infusing them back into the patient.
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Axi-cel belongs to a new class of therapies called chimeric antigen receptor T-cells (CAR-T) using a complicated process of extracting immune system T cells from an individual patient, altering their DNA to sharpen their ability to spot and kill cancer cells, and infusing them back into the patient.
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" Scientists have been studying the chimeric behavior of cephalopods since at least the fourth century BCE, when Aristotle described the octopus in Historia animalium, remarking that that it "seeks its prey by so changing its colour as to render it like the colour of the stones adjacent to it; it does so also when alarmed.
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Because each of these reengineered cells is a monstrous robocop-like assemblage of immune cell parts, researchers had given their invention the equally monstrous name of "Chimeric Antigen Receptor T cell" (in Greek mythology, the chimera is a patchwork monster combining aspects of a lion, goat, and serpent), but "CAR-T" sounds much better.
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Yescarta, approved by the U.S. Food and Drug Administration in October for aggressive large B-cell lymphoma that did not respond to other treatments, is part of a new class known as chimeric antigen receptor T-cell therapies, or CAR-Ts, designed to reprogram the body's own immune cells to recognize and attack malignant cells.
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CMS, which runs the federal government's healthcare plan for seniors, will cover the therapies when provided in certain healthcare facilities, the regulator said here Chimeric antigen receptor T-cell therapy, known as CAR-T, involves drawing white blood cells from a patient, processing them in the lab to target cancer, and infusing the cells back into the patient.
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The value of breakthrough therapies, such as Kymriah, the first approved Chimeric Antigen Receptor Therapy (CAR-T) should be evaluated with the following filters: Are these therapies providing incremental and meaningful benefit versus the available 'standard of care' and with a risk profile that is manageable for most of the patient population it will be used in?
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After being briefed about a recent chimeric incursion, you explore your HQ, upgrading your equipment, completing some fetch quests, and trying to squeeze any bit of charm you can out of the game's mostly one dimensional supporting cast—a too-large crew featuring your standard archetypes, like suspicious scientist, hard-assed mentor, and naive do-gooder.
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SIGNS BINDING LETTER OF INTENT FOR DEVELOPMENT OF NEW CAR-T TECHNOLOGIES * SAYS IMMEDIATE FOCUS WILL INVOLVE PRECLINICAL WORK IN SUPPORT OF A NEW IND APPLICATION OF A CAR-T FOR HEMATOLOGICAL MALIGNANCIES * SAYS FINALIZATION OF COLLABORATIVE BINDING LOI WITH PROMAB BIOTECHNOLOGIES TO DEVELOP CHIMERIC ANTIGEN RECEPTOR CAR-T FOR HEMATOLOGICAL MALIGNANCES AND SOLID TUMOURS * SAYS UNDER AGREEMENT,CO RETAINS EXCLUSIVE LICENSE FOR COMMERCIALIZATION OF PRODUCT CANDIDATES DEVELOPED ALONE OR IN COMBINATION WITH DOS47 Source text for Eikon: Further company coverage:
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This daily medication is the difference between life and death for so many people, but only if they can afford the $97 per pill for the name-brand version or the at least $49 for the generic option in the U.S. Additionally, the pharmaceutical industry takes all the credit for developing the breakthrough gene-altering chimeric antigen receptor T-cell (CAR T) therapy — a therapy that can cost patients $475,000 — even though the first two CAR T treatments for multiple myeloma came out of NIH-funded research.
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