29 Sentences With "be deleterious to" | Random Sentence Generator

That kind of intensity could be deleterious to the songwriting process.

" But the former president said that he is afraid Bolton's "influence on President Trump will be deleterious to our country.

Both mutations are predicted to be deleterious to protein function.

Additionally, induced mutations in these -35 and -10 promoter sequences have proven to be deleterious to transcription.

Thus, outcrossing, promoted by the necessity for union of opposite mating types, likely provides the benefit of masking recessive mutations that would otherwise be deleterious to sexual spore formation (see Complementation (genetics)).

In addition, the operating room environment must be monitored for ambient temperature and humidity, as well as for accumulation of exhaled inhalational anesthetic agents, which might be deleterious to the health of operating room personnel.

The underwater sound pressure caused by pile-driving may be deleterious to nearby fish.Halvorsen, M. B., Casper, B. M., Woodley, C. M., Carlson, T. J., & Popper, A. N. (2012). Threshold for onset of injury in Chinook salmon from exposure to impulsive pile driving sounds. PLoS ONE, 7(6), e38968.

Various types of prepared fish food In the wild, the diet of goldfish consists of crustaceans, insects, and various plant matter. Like most fish, they are opportunistic feeders and do not stop eating on their own accord. Overfeeding can be deleterious to their health, typically by blocking the intestines. This happens most often with selectively bred goldfish, which have a convoluted intestinal tract.

This has prompted many ISPs to offer DSL services without phone service. A new wire is simply run to the premises requiring the service, bypassing the need for any further local loop unbundling agreements. Despite the improvement of the internet in Thailand, there are still network issues, mostly concerning network latency. The delay on the network itself proved to be deleterious to competitive online gaming.

Six microsatellites were examined looking at the current population in 2008 as well as museum samples from 1895 to 1989. One of the microsatellite alleles examined has fixed within the population prior to 1895. For the current population all six microsatellites as well as all sixteen alloenzymes analyzed were fixed. Fixed alleles can often be deleterious to populations, especially when there is a small population size and low genetic variability.

There are reports that indicate amyloid polymers (such as those of huntingtin, associated with Huntington's disease) can induce the polymerization of essential amyloidogenic proteins, which should be deleterious to cells. Also, interaction partners of these essential proteins can also be sequestered. All these mechanisms of toxicity are likely to play a role. In fact, the aggregation of a protein generates a variety of aggregates, all of which are likely to be toxic to some degree.

He subsequently operated a lucrative parking lot across the street from the Forum, home of the Montreal Canadiens hockey club, in downtown Montreal. He also participated in many maverick campaigns and was an outspoken crusader against the marketing of cow's milk, which he believed to be deleterious to human health. He died at his home at 1430 Chomedey St., Montreal, on August 25, 1993. He is the father of Montreal journalists JD Gravenor and Kristian Gravenor.

Of the four DNA damage checkpoints, two have an additional process for monitoring DNA damage other than activating p53. Before entry into S phase and during S phase, ATM/R also activates Chk1/2 that inhibits Cdc25A, a protein responsible for activating cyclin-Cdk dimers. Without cyclin dimer activation, the cell cannot transition through the cycle. These two checkpoints have additional processes for regulation because replicating damaged DNA in S phase can be deleterious to the cell and more importantly, the organism.

Professor Farnsworth assembles the Applied Physics Department faculty of Mars University and Amy explains her idea, demonstrating that the reverse rotation will not be deleterious to Earth. The plan works and the machine reclaims Earth's rotational energy from Thuban 9, now spinning in the opposite direction. In recognition of her achievement, Amy receives her doctorate in applied physics, now "Doctor Wong". However, she remains with Planet Express because the job market is poor while Nibbler reconciles with Leela, appreciating that she cares for him.

Several intronic variants have been associated with addiction and were found to alter the function of brain regions responsible for reward anticipation. This link to addiction is supported by animal models, where loss of kalirin results in altered cocaine self-administration and synaptic and expression changes in response to cocaine. Perhaps the most compelling genetic links are between kalirin and schizophrenia. Numerous missense mutations in KALRN have been identified in exome sequencing studies of schizophrenia cohorts that are predicted to be deleterious to protein function.

In the contest, Bradford was supported by Democrat James Michael Curley, who was contesting with Tobin for control of the state Democratic party apparatus. As governor, Bradford governed in the fashion of his mentor, Leverett Saltonstall, with an emphasis on fiscal conservatism and social liberalism. During his administration, he advanced balanced budgets and intervened to prevent protracted strikes, which would be deleterious to the interests of business and the broader public. His administration worked to promote public housing for veterans and prevent alcoholism through treatment and prevention programs.

The crab may be immune to or able to tolerate the jellyfish stings. It is thought that the crab benefits from using the jellyfish as a nursery because free-living, young crabs are eaten by predatory fish. Other benefits of this arrangement to the crab are a potential increase in food supply and transport to new locations. There do not seem to be any benefits to the jellyfish and the arrangement may be deleterious to it if the crab nibbles its interior tissues, as happens in some other crab/jellyfish relationships.

For instance, in People v. Melvin, cordwainers were again convicted of a conspiracy to raise wages. Unlike in Pullis, however, the court held that the combination's existence itself was not unlawful, but nevertheless reached a conviction because the cordwainers had refused to work for any master who paid lower wages, or with any laborer who accepted lower wages, than what the combination had stipulated. The court held that methods used to obtain higher wages would be unlawful if they were judged to be deleterious to the general welfare of the community.

Justice Frankfurter, a former professor at Harvard Law School, wrote a concurrence that centered on the principles of academic freedom, and how they would be affected by governmental interference. Joined by Justice Harlan, Frankfurter noted that "a free society [depends] on free universities", and that institutions of higher education were shielded, in part, from the intervention of governmental authorities, which would be deleterious to the "intellectual life" of the university. He ultimately concluded that: "In the political realm, as in the academic, thought and action are presumptively immune from inquisition by political authority." Justice Tom C. Clark dissented, joined by Justice Burton.

Mitochondrial damage is not caused solely by oxidative stress or disease processes; normal mitochondria will eventually accumulate oxidative damage hallmarks overtime, which can be deleterious to mitochondria as well as to the cell. These faulty mitochondria can further deplete the cell of ATP, increase production of ROS, and release proapoptopic proteins such as caspases. Because of the danger of having damaged mitochondria in the cell, the timely elimination of damaged and aged mitochondria is essential for maintaining the integrity of the cell. This turnover process consists of the sequestration and hydrolytic degradation by the lysosome, a process also known as mitophagy.

J.,5,147-162 Metabolic engineering continues to evolve in efficiency and processes aided by breakthroughs in the field of synthetic biology and progress in understanding metabolite damage and its repair or preemption. Early metabolic engineering experiments showed that accumulation of reactive intermediates can limit flux in engineered pathways and be deleterious to host cells if matching damage control systems are missing or inadequate. Researchers in synthetic biology optimize genetic pathways, which in turn influence cellular metabolic outputs. Recent decreases in cost of synthesized DNA and developments in genetic circuits help to influence the ability of metabolic engineering to produce desired outputs.

At approximately 9 months gestation, the fetus's energy needs surpasses the mother's energy limitation, correlating with the average time of birth. The newly born infant can then be sustained on breast milk, which is a more efficient, less energy demanding mechanism of nutrient transfer between mother and child. Additionally, this hypothesis demonstrates that, contrary to the obstetrical dilemma, an increased pelvic size would not be deleterious to bipedalism. Studying the running mechanics of males and females, it was shown that an increased pelvic size related to neither an increased metabolic nor structural demand on a woman.

As mentioned above, aryl and alkenyl nonaflates are useful as electrophiles in palladium catalyzed cross coupling reactions. Their reactivity generally mirrors that of the more commonly encountered triflate electrophiles, but nonaflates tend to be less prone to hydrolysis to ketones (in the case of alkenyl sulfonates) and phenols (in the case of aryl sulfonates). Their resistance to hydrolysis makes nonaflates superior electrophiles in Buchwald-Hartwig couplings, where this side reaction can be deleterious to yields of the desired product. The sodium enolates of β-ketoesters react with 1.15 equivalents of NfF to give the corresponding alkenyl nonaflates in high yield.

Upon establishing "Forough's School", some religious extremists threatened to set fire to this school, which was held at her private home. To counter this threat, she, along with her children and members of her extended family, protected the school by the force of arms, a measure that was kept in place for two years. The problem was ultimately resolved as a result of Forough's discussions with the religious leaders of Mashhad, who at first had considered presence of girls in a school environment as being against religious teachings. Having convinced the citizens that studying would not be deleterious to women, the School for Women (مدرسه بانوان) in Mashhad was formally inaugurated.

The state's policy was to house death row prisoners in solitary confinement, but lengthy appeals have created new harsh conditions of extended solitary. Convicts and their defense counsels have challenged such lengthy stays in solitary confinement, which has been shown to be deleterious to both mental and physical health, and has been considered to be "cruel and unusual punishment" under the US Constitution. In March 2019, seven members of staff at the facility were arrested for rape, smuggling items to inmates and maintaining personal relationships with prisoners. In 2020 the COVID-19 pandemic in Louisiana affected Angola, with ProPublica stating that deliberate low testing rates masked an epidemic in the prison.

Amotz Zahavi used the excessive tail plumes of male peafowls as evidence for his "handicap principle". Since these trains are likely to be deleterious to an individual's survival (as their brilliance makes them more visible to predators and their length hinders escape from danger), Zahavi argued that only the fittest males could survive the handicap of a large train. Thus, a brilliant train serves as an honest indicator for females that these highly ornamented males are good at surviving for other reasons, so are preferable mates. This theory may be contrasted with Ronald Fisher's theory (and Darwin's hypothesis) that male sexual traits are the result of initially arbitrary aesthetic selection by females.

Environmental impact assessments found that this dam would be deleterious to a variety of large game animals, including big-horned sheep and elk. While the Libby Dam opened the possibilities of downstream irrigation, scientists determined that it would also destroy valuable wetland ecosystems and alter the river hydrology throughout the area of its extent, in the reservoir and far downstream. Under pressure from environmental activist groups, the Army Corps of Engineers developed a mitigation plan that represents a major departure from the previous treaty dams. This plan addressed concerns about fish by building hatcheries, acquired land to serve as grazing areas for animals whose normal ranges were submerged, and implemented a technological fix as part of the dam project that enabled control of the temperature of water released from the dam.

Sprung and unsprung mass are shown Sprung mass (or sprung weight), in a vehicle with a suspension, such as an automobile, motorcycle, or a tank, is the portion of the vehicle's total mass that is supported by the suspension, including in most applications approximately half of the weight of the suspension itself. The sprung mass typically includes the body, frame, the internal components, passengers, and cargo, but does not include the mass of the components at the other end of the suspension components (including the wheels, wheel bearings, brake rotors, calipers, and/or continuous tracks (also called caterpillar tracks), if any), which are part of the vehicle's unsprung mass. The larger the ratio of sprung mass to unsprung mass, the less the body and vehicle occupants are affected by bumps, dips, and other surface imperfections such as small bridges. However, a large sprung mass to unsprung mass ratio can also be deleterious to vehicle control.