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"heritable" Definitions
  1. (of property) that can be passed from one member of a family to another
"heritable" Antonyms

181 Sentences With "heritable"

How to use heritable in a sentence? Find typical usage patterns (collocations)/phrases/context for "heritable" and check conjugation/comparative form for "heritable". Mastering all the usages of "heritable" from sentence examples published by news publications.

These characterological attitudes are highly heritable — about 50 percent heritable.
By definition the gene was the carrier of any trait that is heritable or partly heritable.
These observations do not undermine the conclusion that intelligence is heritable, but rather the naive assumption that heritable traits cannot be changed via environmental mechanisms.
It's just that nothing that complex is 250 percent heritable.
Both cases involve Huntington's disease (HD), a heritable neurodegenerative disorder.
"We have to know if the trait is heritable," Susan replies.
Intelligence is highly heritable and perhaps the best predictor of success.
Like mental illness, the talent for magic is a heritable quality.
The societal risks of heritable genome editing, while often downplayed, are grave.
Bowman is also worried because the genetic changes in the monkeys were heritable.
Less severe nausea and vomiting has also been shown to be strongly heritable.
The personality that they inherited, you'd be surprised how heritable personality traits are.
The consensus, he says, is that IQ exists; that it is extraordinarily important to life outcomes of all sorts; that it is largely heritable; and that we don't know of any interventions that can improve the part that is not heritable.
"Eating lots of sugar speeds up the loss of your heritable microbes," Dupont said.
Dr. Zaidi and his colleagues also demonstrated that nose shape is a heritable trait.
Importantly, these modifications were made to germline cells, which means this trait is now heritable.
This means the genetic changes can be introduced later in life, and they aren't heritable.
Even someone's likelihood of being religious (103-40%) or of getting divorced (13%) is heritable.
Some proponents of heritable genome editing argue that "safe" application is just around the corner.
In other words, does the study give us a reason to oppose heritable genome modification?
Indeed, a 2015 study of twins found that wakefulness is significantly heritable, especially in women.
No common psychiatric condition is fully heritable, meaning that the environment always plays a role.
That goes against international paradigms for not engaging in the manipulation of heritable genomic data.
He believed this was a heritable trait, and he helped launch the American eugenics movement.
How can we understand how a trait can be both heritable and influenced by environment?
Among the prominent issues: the argument for the technique's medical necessity is shaky since alternatives exist; the risks to any resulting children are significant; and the likelihood that allowing heritable mitochondrial changes will be leveraged to open the door to all heritable modifications is great.
Brother, sister, or cousin pairs can lead to heritable diseases and other problems with genetic diversity.
Here the author again parallels Kraepelin, who stressed the contribution of heritable "degeneracy" to mental disorders.
There are still too many risks, too many unknowns, about tinkering with our heritable genetic blueprints.
Skin color is a heritable condition, meaning it is trait passed down to you by your parents.
" Later, the recommendations suggest that "genetic screening for heritable diseases should be performed in potential sperm donors.
"The risk for this is heritable, but why and when it starts is not really understood," she said.
The technology is seen as potentially useful for removing heritable diseases or for reducing genetic predispositions to cancer.
Charles Murray has famously (and for many, infamously) argued that disparities in wealth reflect heritable differences in intelligence.
These traits could be made heritable, such that Martian colonists could pass down the characteristics to their offspring.
Heritability is not unique to IQ; in fact, virtually all differences among individual human beings are somewhat heritable.
Dr. Lea said that declining sperm motility, the most pronounced effect, does not have a strong heritable association.
This is true but irrelevant: It is merely evidence that IQ is partly heritable, which no one disputes.
In The Bell Curve, race — that is, racial differences tied to heritable genetic traits — serves the same function.
R. Alta Charo, a leading American bioethicist and the co-chair of the report, insisted during the report's release panel today that genome editing, both somatic (non-heritable changes to genes) and germline (changes that are heritable) should be used for the treatment and prevention of disease and disability only.
In particular, the study raises the stakes for those who wish to make heritable changes to the human genome.
Oxitec's GM mosquitos carry a heritable genetic trait which renders any offspring unable to survive without the antibiotic tetracycline.
But Congress has banned the agency from reviewing any proposal that involves making heritable genetic modifications in an embryo.
But the use of heritable genetic alterations to reduce or eliminate genetic diseases will not and cannot end there.
So there's a chance that Harper does actually have a mutation, or some other heritable factor of heart disease.
To put it simply, the marks can either turn "on" or "off" certain heritable traits in children since birth.
Studies of twins have backed this up: they suggest that vulnerability to P.T.S.D. is thirty to forty percent heritable.
The effects of the disease are heritable, suggesting the virus encodes its DNA into the germline cells of its hosts.
A study of twins suggested that a liking for meat is highly heritable, so there could be a genetic element.
Even one of the most heritable disorders, schizophrenia, appears linked to small variations in more than a hundred genetic regions.
Biomedical research that marries family trees with genetic and health information could lead to new discoveries about heritable disease risk.
What I've been really vocal about avoiding is the former situation where you would use CRISPR to create heritable changes.
In parallel, scores of studies identified heritable gene sequences that seemed to be associated with an increased risk for addiction.
The experiment was deemed unethical owing to the nascent state of CRISPR technology, and also because the unproven modifications are heritable.
How can this be, given that intelligence is highly heritable, and clever folk breed no more prolifically than less gifted ones?
We'll deploy gene editing tools far more precise than today's CRISPR systems to make heritable genetic changes to our future offspring.
He said he and some colleagues had recently conducted a study that suggested postpartum depression was more heritable than general depression.
There's no one who's arguing that any of these traits — forget about intelligence, anything we care about — is 503 percent heritable.
The laws of genetics, as laid out by Gregor Mendel, dictate that genes pass between generations in heritable and predictable ways.
"Twin studies show it's about 25 percent heritable, but that means it's 75 percent social circumstances or under our own control."
Trump himself is a "good genes" guy, espousing — in his own anti-intellectual, offhand way — a genetic theory of heritable superiority.
A huge issue with this form of gene-editing is that it's done on germline cells, which means introduced traits are heritable.
The other strains are less strongly heritable, meaning family history is a useful part of a diagnosis, but not more than that.
A central registry for both somatic (non-heritable) and germline genetic cell research is key for transparency and increasing accountability, Hamburg says.
Similar surprisingly heritable traits include a child's tendency to be bullied at school (more than 70%) or to be accident-prone (51%).
"One of the things that's really interesting about psychiatric disease is that it's more heritable than many other diseases," Dr. Gerstein said.
As a result, the best place for biological scientists to find traction is with individuals who have highly heritable, narrowly defined problems.
Conceptually, a key element of classical Darwinian evolution is that genes do not retain an organism's experiences in a permanently heritable manner.
Before even running the races, Winchell developed a way to show that the changes had a genetic component and were therefore heritable.
Block's point, and this is important, is not that IQ isn't heritable, or even that it's impossible to imagine it differing among groups.
By inserting a snippet of the LD gene into yeast, Lindquist created a protein that misfolds, and spreads misfolding in a heritable manner.
More important, there was an expectation that the heritable causes of things like heart disease might be pinned down to such genetic handfuls.
The same framework has since been used to understand other heritable forms of cancer, such as the BRCA1 gene associated with breast cancer.
We also already have good reason to conclude that heritable genome modification is unacceptably risky and that medical justifications for it are tenuous.
And Dr. Tatonetti was surprised to learn during the research that runny noses are highly heritable — a trait confirmed by his data set.
Scientists in the US may be fiddling with similar sorts of heritable modifications in mice but have no plans to do so in people.
On Thursday, the FDA approved genetic testing company 23andMe to sell customers foreshadowing about their susceptibility to these, and seven other heritable genetic traits.
The Food and Drug Administration told 23andMe to stop offering information on potentially heritable diseases in 2013, before partially reversing that decision last year.
"Our results provide compelling evidence that all human traits are heritable: not one trait had a weighted heritability estimate of zero," the paper concluded.
It is used for cousin and distant relative matching as well as ethnic mixture percentages and genetic traits like heritable diseases and eye color.
DNA damage is worse: Cells attempt to repair their own wreckage, but mis-repairs accumulate, leading to mutations that cause cancer and heritable diseases.
In her report, Lipner describes this as a "relatively common physical examination finding" that has been linked to infections, medications, autoimmune and heritable conditions.
Intelligence is heritable, and for a long time, researchers assumed that people with high IQ scores would have kids who also scored above average.
Mutations like these happen to be heritable, which would conceivably allow scientists to create stocks of mutant wasps should they require lots of them.
Research shows that, while heritable, highly polygenic traits — those determined by multiple genes—are often determined by the collective contribution of hundreds of genes.
They analyzed heritable and environmental factors across 25 common conditions and diseases spanning 260 categories, ranging from cardiovascular illness and neuromuscular diseases to skeletal conditions.
The symptoms are thought to be that of epidermodysplasia verruciformis, a rare, heritable disease; there have only been a handful cases reported around the world.
The UK is the first country to legalize the use of MRT, but only for women with heritable mitochondrial disease, and only under strict oversight.
Dead or poorly functioning cells cause heart disease or cognitive decline; if cells cannot repair DNA damage, mutations accumulate that cause cancer and heritable diseases.
While the levels of heritability for addiction are different for each substance in question, "all addictions have at least some heritable component," explains Dr. Bryant.
Some research indicates that people with a certain variation of a heritable enzyme called COMT learn more rapidly from their mistakes and weigh potential rewards better.
Statistical research on Swedish twins by Tove Fall of Uppsala University and others suggests that more than half of the propensity to own dogs is heritable.
These policy decisions were motivated in large part by concerns that heritable genome modification would exacerbate inequality and discrimination, and enable a new market-based eugenics.
Her studies revealed particular individuals, such as those with the CD83 genotype (a variation of heritable genetic identity) are less receptive to the hormone than others.
But to the extent that these traits arise from brain processes (and there's a lot of evidence that they do), there may be a heritable component.
Again, because all human traits are in part heritable, scientists and the media need to be careful when they claim research has found the "gene for" anything.
That provided justification for professional analysis of Yuna's gene to determine if there was a heritable mutation the Lees could have also transmitted to their second child.
It's important to note that in UPenn's proposed experiment, the gene therapy is somatic, not germline, which means that whatever genetic alterations are made won't be heritable.
This delayed sleep phase is believed to be partly heritable, and one recent study even claimed that it can be the result of a specific genetic mutation.
But, if epigenetic information can be transmitted through sperm and eggs, an organism would seem to have a direct conduit to the heritable features of its progeny.
Damore argues that "highly heritable" personality traits (including higher "agreeableness" and a preference for "artistic" jobs among women) are responsible for gender gaps in tech, ignoring cultural explanations.
It is used for cousin and distant relative matching as well as mixture percentages, or your ethnic mix, plus common genetic traits, like heritable diseases and eye colour.
Long-term positives could include the reduction of risk factors for chronic disease and an increase of awareness for the heritable and environmental factors to dangerous eating behaviors.
Churchland and I recently talked about how brain differences, which are underwritten by differences in our genes, shape our moral attitudes — and how those can be highly heritable.
Many Hispanics in the region share a gene mutation with other Jews around the world that causes heritable breast cancer, confirming whispers in some families about Jewish ancestry.
But new studies have indicated that although prosopagnosia can result from a stroke or traumatic brain injury, it is a heritable condition that is sometimes present from birth.
An identical and fraternal twin study published in Behavior Genetics suggests that 60 percent of differences in men's desire for new, unusual, and risky experiences ("sensation seeking") is heritable.
Why it matters: The global scientific and ethical community continues to be divided on whether there should be a complete moratorium on editing germline, or heritable, cells for now.
When we think about CRISPR/Cas9 we tend to think of it as a tool to eliminate heritable genetic diseases, or as a way to introduce new genes altogether.
But the really big question — the stuff of sci-fi — is whether we'll use genome-editing tools on people to wipe out heritable diseases or to enhance human capabilities.
Psychopathy is heritable, at least in part, as revealed by analysis of identical twins -- however, keep in mind that most mental issues are a combination of nature and nurture.
The stakes of each game session are nothing less than the stakes of empires; you can watch your heritable line fizzle into nothing or bloom into a powerful dynasty.
And even if we could understand all the physiological and health effects that heritable genome modification would produce, we would still need to consider its unacceptably dangerous social consequences.
In the southwestern part of modern China, tribal elders were granted the new title of tusi — literally, earth lords — an official and heritable status recognized by the Chinese bureaucracy.
The study sought to correct a mutated version of the MYBPC3 gene, which causes hypertrophic cardiomyopathy, a heritable disease that leads to sudden cardiac failure, often in young athletes.
Because with such fine-tuned command of the genetic code, prime editing could, according to Liu's calculations, correct around 89 percent of the mutations that cause heritable human diseases.
Fox's research has isolated some of the brain functions tied to "heritable" anxiety, and he says about a third of anxiety variation across individuals is attributable to their DNA.
It's time to step back from the brink, and to deliberate carefully and collectively about whether the future to which we aspire should include any form of heritable genome modification.
Studies of twins suggest that our pain response is, in part, heritable, but there are close correlations between chronic pain and many other factors—gender, age, stress, poverty, and depression.
She says the use of the term "heritable" in the bill's language that refers to the genetic modification being banned could prove important to the fate of mitochondrial replacement therapy.
Others have suggested that it comes down to heritable traits that could confer an evolutionary advantage on one sex, but not the other, when it's time for offspring to reproduce.
That means changing DNA in the cells of an individual, not in a way that becomes heritable by future generations, but just in a way that affects that individual patient.
Germline changes to mitochondrial DNA are not heritable via the male line, which is why girls are being excluded (actually, males can pass the trait down one generation, but no further).
First of all, when someone hears the term heritability estimate, or how heritable something is, people assume that means that is how much their genes determine the outcome of that trait.
If the FDA were to move forward with clinical testing involving male embryos only, the mitochondrial replacement "would not be heritable because it would stop with that first generation," she says.
So if we go in and we edit embryos and the heritable traits; if we start to see that happen on a large scale, we can change the human genetic pool.
Somatic gene editing, on the other hand, in which a living person's DNA is altered to treat various maladies, from cancer through to hemophilia, results in genetic changes that are not heritable.
He has proposed a "500-year plan" for space colonization, whose most radical suggestion is adding, deleting, or modifying genes to create permanent, heritable changes in a new species of spacefaring hominins.
Aside from the fact that the title of chief executive, the highest office in Hong Kong today, is not heritable, Leung Chun-ying, the city's outgoing leader, is a modern-day tusi.
The discovery of ABO blood types at the turn of the century led, in the nineteen-tens, to research by the Polish microbiologist Ludwik Hirszfeld which showed that blood groups were heritable.
As for gene editing, we are already beginning to use that in non-germ-line cells, where such changes are not heritable, in order to treat blood, neurological, and other types of diseases.
These types of heritable pain conditions are extremely rare and, arguably, these studies of profound genetic variations reveal little about more subtle variations that may contribute to individual differences in the normal population.
The new DNA-based science has also led to an ironic discovery: Virtually none of the complex human qualities that have been shown to be heritable are associated with a single determinative gene!
The federal Advisory Committee on Heritable Disorders in Newborns and Children makes recommendations on what conditions should be added to newborn screenings, which are then passed onto the Recommended Uniform Screening Panel (RUSP).
Lydia is relieved to hear she has little chance of developing her mother's cancer, but expresses exactly zero interest in knowing more about her father's early Alzheimer's disease, a far more heritable condition.
If qualities like ignorance and vice were heritable, the long-term solution was not better schools and better jails — though progressives wanted those, too — but rather a tidying up of the gene pool.
In 2001, Fisher, then at Oxford, was part of a team that discovered the FOXP2 gene and identified a single, heritable mutation of it that is responsible for verbal dyspraxia, a severe language disorder.
While there's the potential to eliminate certain heritable genetic diseases in the future, there's also broad acceptance that it's simply too early to experiment with germline editing that would lead to genetically modified children.
The use of CRISPR in modifying human embryos with certain heritable diseases was just approved this week by a science advisory panel formed by the National Academy of Sciences and the National Academy of Medicine.
While this behaviour is still rare, they argue that if the tendency is driven by heritable genes (which it may well be) then a succession of early springs could make the strategy much more common.
"Funny as it may sound, heritable cancer was hardly discussed in the 2000s and 22004s," Dr. Albert de la Chapelle, a professor in the human genetics program at Ohio State University, said in an email.
Peterson says that IQ is a single, irreducible heritable trait, and then argues that smart people have more cognitively difficult, higher-paying jobs, while people with IQs below 83 have no place in modern society.
Giraffes, he proposed, arose through heritable variation and natural selection—a tall-necked specimen appears in an ancestral tree-grazing animal, and, perhaps during a period of famine, this mutant survives and is naturally selected.
There does seem to be at least some genetic component to perfectionism, but to what extent it's an innate, heritable disposition versus something that's learned or provoked by one's environment isn't completely clear, Flett explained.
" According to the Canadian Journal of Plastic Surgery, the condition "is a rare, heritable disease characterized by an unusual susceptibility to infection with specific types of human papillomavirus and a propensity for developing malignant skin tumors.
Since certain mental conditions also tend to run in families, Fair's mission to detect heritable connections might eventually help discern the parts of the brain and genes that increase a person's risk of developing specific disorders.
Liberals need not deny that intelligence is a real thing or that IQ tests measure something real about intelligence, that individuals and groups differ in measured IQ, or that individual differences are heritable in complex ways.
The classic example is height, which is strongly heritable (33 to 90 percent), yet the average height of 11-year-old boys in Japan has increased by more than 5 inches in the past 50 years.
According to the authors of the Nature Genetics study, fathers with a heritable mental illness may simply be more likely to have children at the extremes of age -- perhaps because they socialize or take risks differently.
It is used for cousin and distant relative matching as well as mixture percentages, or your ethnic mix (as shown in those fancy pie charts from the commercials), plus common genetic traits, like heritable diseases and eye color.
An influential national advisory panel said on Tuesday that such heritable changes should be allowed only in the narrowest of circumstances, to prevent infants from acquiring genes that would cause serious diseases, and only when there was no alternative.
A survey of physicians conducted for STAT News found that 23 percent of doctors think analyzing a patient's family medical history will offer them and their patients better clues than genome sequencing in gauging the likelihood of a heritable cancer.
National Institutes of Health director Francis Collins and top science and ethics experts in the U.S. and 6 other countries today called for an international 5-year moratorium on editing human germlines, or the type of genes that are heritable.
Mukherjee's readers would have been capable of understanding that a methyl group is added to C, one of the four bases that encode DNA, but only at very specific sites, to silence gene expression in a way that is heritable.
It will be some time before CRISPR will safely be used to alter the heritable traits of humans, but that day will come because, like embryo selection, precision gene editing will help us fight disease and live healthier and longer.
Large scale twin studies have shown that conditions like severe depression are at least partly heritable—meaning that genes are one of many factors that can influence these conditions—but scientists have struggled to connect that influence with specific genes.
He had also reportedly been trying to convince the government of the southern province of Hainan to launch IVF clinics that specialized in germline editing — which involves tinkering with the DNA in embryos, eggs, and sperm to alter heritable traits.
"We were able to calculate for the first time that there is a heritable component to age at first sex, and the heritability is about 25 percent, so one quarter nature, three quarters nurture," lead study author John Perry told the Guardian.
This study was a big deal because while we've known intelligence is largely heritable, we haven't understood the specifics of the biology of IQ — why it can be so different between people, and why we can lose it near the end of life.
Despite an independent bioethics committee finding that the FDA should approve clinical trials for MRT, if only with male embryos (which would not be able to pass on a heritable mitochondrial illness, should something go wrong), the FDA chose to reject the idea.
To say that intelligence is heritable means that, in general, people who are more similar genetically are also more similar in their IQ. Identical twins, who share all their DNA, have more similar IQs than fraternal twins or siblings, who only share half.
Once scientists and regulators are confident they have minimized the potential risks of IVG, we could easily make heritable changes to germ cells like eggs, sperm, or early-stage embryos, and with those changes, we'd be altering the germ line, our shared human inheritance.
In its new report, "Genome Editing and Human Reproduction: Social and Ethical Issues," the Nuffield Council has concluded that it is "morally permissible" to edit the DNA of a human embryo, sperm, or egg to alter a future person's characteristics, such as eliminating heritable diseases.
Its three main components are expanding our knowledge of genomics, including determining which genes should wear a "do-not-disturb sign," because their alteration would kill or disable us; engineering microbes; and adding, deleting, and modifying genes to create permanent, heritable changes in a population.
"The genetic component is estimated to account for 50 to 70 percent of the risk of developing an eating disorder, which is fairly substantial, making it one of the most heritable psychiatric disorders," said Michael Lutter, a psychiatrist at the Eating Recovery Center in Dallas.
"There is potential for heritable genome editing interventions to be used at some point in the future in assisted human reproduction, as a means for people to secure certain characteristics in their children," said Karen Yeung, the chair of the Nuffield Council working party, in a statement.
With all this very heritable variation at play between penis length and flirting style in male swordtails, researchers at the Instituto de Ecología, A.C. in Veracruz, México investigated how female fish navigate a chaotic medley of dicks and flashy performances, judging and choosing their preferred partners.
The U.K.-based bioscience company makes DNA modification analysis tools for epigenetics researchers — an emerging field of study which looks at how environmental factors and other dynamic/behavioral elements can have a heritable impact, based on how they regulate gene expression rather than changing the underlying DNA.
Top global scientists declined to declare the moratorium on gene editing heritable genes in humans called for by some experts, but warned it would be "irresponsible" to allow this in clinical practice and recommended initial steps for a global regulatory framework under the World Health Organization.
However, before routine genetic screening of infants even approaches reality, many questions need answers, including whether genetic sequencing can accurately identify babies who will develop a disease, according to Dr. Joseph A. Bocchini Jr., chairman of the Advisory Committee on Heritable Disorders in Newborns and Children.
Dr. Fox believes that this kind of legal action in American courts could helped aggrieved clients fight a litany of actions and inaction committed by clinics — failing to test sperm donors for serious and highly heritable conditions, for example, or neglecting reliable methods to label sperm samples.
Based on the results of a genetic test, patients may be faced with serious decisions—like say, whether or not to have children if they have certain heritable conditions, or whether to take preventative health measures like a mastectomy for women that test positive for harmful mutations of the BRCA genes.
To be deemed ethical, the council said heritable genome editing interventions must adhere to two overarching principles: They "must be intended to secure, and be consistent with, the welfare of the future person," and "they should not increase disadvantage, discrimination or division in society," write the authors of the report.
As powerful as the gene-editing technique Crispr is turning out to be—researchers are using it to make malaria-proof mosquitoes, disease-resistant tomatoes, live bacteria thumb drives, and all kinds of other crazy stuff—so far US scientists have had one bright line: no heritable modifications of human beings.
The problem of unpredictable effects is especially acute with some energy and all geoengineering technologies; with biotechnologies such as gene drives that can force a genetic modification through an entire population in a few generations; with artificial eggs and sperm that might allow parents to augment their offspring with heritable traits.
British law bans this at the moment, but the Nuffield panel of experts said it could, in time, become available as an option for parents wanting to influence the genetic characteristics of their future child - for example, to "edit out" a heritable disease or a predisposition to cancer in later life.
Congress began looking into gene editing last year with hearings led by House Science, Space and Technology committee Chair Lamar Smith (R-TX), who believes that the US should proceed with severe caution when it comes to genetically altering embryos with heritable changes, even if it means putting off curing diseases. Rep.
The various states that are carriers for college basketball's particular heritable madnesses had their local heroes and made those teenagers into little gods in all the usual ways, but those big programs also imported sinewy point guards and bowling ball power forwards from those Jesuit basketball academies and concrete-town public schools.
Murray and Herrnstein's book, The Bell Curve, was published in 211, generating immediate controversy for its arguments that IQ was heritable, to a significant degree, and unchangeable to that extent; that it was correlated to both race and to negative social behaviors; and that social policy should take those correlations into account.
We start by noting that we accepted as facts many claims that are controversial in the academy, if not in psychology — that IQ exists; that it predicts many life outcomes; that there is a gap between black IQ scores and white IQ scores; that IQ is at least partly heritable (as is almost every human trait).
They lie at the core of what divides America: These reflect some of the fundamental fault lines of human conflict and are unlikely ever to be resolved or settled because we can't just be socialized or educated out of our stances on these issues, as they are the product of deep-seated, largely heritable predispositions that cause us to vary in our preference for and in our ability to cope with freedom and diversity, novelty and complexity, vs oneness and sameness.

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